4YQOA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
254
structure length
242
Chain Sequence
GLVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 242
sequence length 254
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqoA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqoA01
4YQBA 4CNDA 4YQ7A 2O3AA 3L8UA 3KY7A 4YQSA 4YQLA 1MXIA 3KW2A 4MCDA 1VHYA 1UAJA 3IEFA 2EGVA 3N4JA 3OIJA 1VH0A 3KTYA 4KGNA 2I6DA 4MCCA 4H3YA 1K3RA 4YVJA 2QMMA 4YQJA 3BBHA 5FAIA 4YQGA 3NK7A 1X7PA 4MCBA 2Z0YA 4CNFA 3OINA 4E8BA 3BBDA 3AIAA 2QWVA 4L69A 2HA8A 5CO4A 1Z85A 4YVGA 4IG6A 4YPZA 2V3JA 1V6ZA 4YPWA 4CNEA 4X3LA 3NK6A 4YQ8A 4YQPA 4YQ0A 4X3MA 2V3KA 4YQ4A 4YQ6A 1TO0A 1VHKA 1NXZA 1O6DA 4RG1A 4YQ3A 3BBEA 3E5YA 4H3ZA 4YQDA 4JAKA 3IC6A 3QUVA 3KNUA 4KDZA 4YQ1A 1V2XA 3GYQA 4YPYA 4PZKA 4YQNA 4J3CA 4CNGA 3DCMX 4YQRA 3O7BA 4JALA 4YQKA 4YQ5A 2CX8A 3N4KA 3ILKA 1P9PA 4YQOA 3AXZA 1UAMA 4YQ2A 1J85A 5D9FA 4YVKA 2YY8A 4YQCA 4YPXA 1ZJRA 4YVIA 3AI9X 1X7OA 1OY5A 5GM8A 1NS5A 4XBOA 4YQIA 1GZ0A 4YVHA 4FAKA 4YQTA 4YQ9A 3ONPA 1IPAA 2EGWA 4YQAA 5GMBA 4YQQA 1UAKA 1UALA 3OIIA 5GMCA
chains in the Genus database with same CATH superfamily
4YQBA 3SSXN 4CNDA 4YQ7A 2O3AA 3L8UA 3KY7A 3SSWN 4YQSA 1TROA 4YQLA 1WRTR 1MXIA 3KW2A 4MCDA 1VHYA 1UAJA 3IEFA 2EGVA 3N4JA 1TRRA 3OIJA 1ZT9A 1VH0A 1MI7R 3KTYA 4KGNA 3KORA 2I6DA 1WRPR 4MCCA 4H3YA 1K3RA 4YVJA 2QMMA 4YQJA 3BBHA 5FAIA 4YQGA 3NK7A 1X7PA 4MCBA 2Z0YA 1WRSR 4CNFA 4E8BA 3OINA 3BBDA 3AIAA 2QWVA 4L69A 2HA8A 4JWFA 5CO4A 1Z85A 4YVGA 4IG6A 4YPZA 2V3JA 4JWGA 1V6ZA 4YPWA 4CNEA 4X3LA 3NK6A 4YQ8A 2XDIA 4YQPA 4YQ0A 4X3MA 2V3KA 4YQ4A 4YQ6A 1TO0A 1VHKA 1NXZA 1O6DA 4RG1A 4YQ3A 3BBEA 3E5YA 4H3ZA 4JWJA 3FRWA 4YQDA 4JAKA 3WRPA 3IC6A 3QUVA 3KNUA 4KDZA 3G1CA 4YQ1A 1V2XA 4YPYA 3GYQA 4PZKA 4YQNA 4J3CA 4CNGA 1RCSA 4YQRA 3DCMX 3O7BA 4JALA 4YQKA 4YQ5A 2CX8A 2OZ9R 3N4KA 3ILKA 1P9PA 4YQOA 3AXZA 1UAMA 4YQ2A 1J85A 1CO0A 5D9FA 4YVKA 4JWHA 2YY8A 4YQCA 4YPXA 1ZJRA 4YVIA 3AI9X 1X7OA 1OY5A 1JHGA 5GM8A 1NS5A 4XBOA 4YQIA 1GZ0A 4YVHA 4FAKA 4YQTA 4YQ9A 3ONPA 1IPAA 2EGWA 4YQAA 5GMBA 4FMWA 4YQQA 1UAKA 1UALA 3OIIA 5GMCA
chains in the Genus database with same CATH topology
4YQBA 4CNDA 4YQ7A 2O3AA 3L8UA 3KY7A 4YQSA 4YQLA 1MXIA 3KW2A 4MCDA 1VHYA 1UAJA 3IEFA 2EGVA 3N4JA 3OIJA 1VH0A 3KTYA 4KGNA 2I6DA 4MCCA 4H3YA 1K3RA 4YVJA 2QMMA 4YQJA 3BBHA 5FAIA 4YQGA 3NK7A 1X7PA 4MCBA 2Z0YA 4CNFA 3OINA 4E8BA 3BBDA 3AIAA 2QWVA 4L69A 2HA8A 4JWFA 5CO4A 1Z85A 4YVGA 4IG6A 4YPZA 2V3JA 4JWGA 1V6ZA 4YPWA 4CNEA 4X3LA 3NK6A 4YQ8A 4YQPA 4YQ0A 4X3MA 2V3KA 4YQ4A 4YQ6A 1TO0A 1VHKA 1NXZA 1O6DA 4RG1A 4YQ3A 3BBEA 3E5YA 4H3ZA 4JWJA 4YQDA 4JAKA 3IC6A 3QUVA 3KNUA 4KDZA 4YQ1A 1V2XA 3GYQA 4YPYA 4PZKA 4YQNA 4J3CA 4CNGA 3DCMX 4YQRA 3O7BA 4JALA 4YQKA 4YQ5A 2CX8A 3N4KA 3ILKA 1P9PA 4YQOA 3AXZA 1UAMA 4YQ2A 1J85A 5D9FA 4YVKA 4JWHA 2YY8A 4YQCA 4YPXA 1ZJRA 4YVIA 3AI9X 1X7OA 1OY5A 5GM8A 1NS5A 4XBOA 4YQIA 1GZ0A 4YVHA 4FAKA 4YQTA 4YQ9A 3ONPA 1IPAA 2EGWA 4YQAA 5GMBA 4FMWA 4YQQA 1UAKA 1UALA 3OIIA 5GMCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQB A;  4CND A;  4YQ7 A;  2O3A A;  3L8U A;  3KY7 A;  4YQS A;  4YQL A;  1MXI A;  3KW2 A;  4MCD A;  1VHY A;  1UAJ A;  3IEF A;  2EGV A;  3N4J A;  3OIJ A;  1VH0 A;  3KTY A;  4KGN A;  2I6D A;  4MCC A;  4H3Y A;  1K3R A;  4YVJ A;  2QMM A;  4YQJ A;  3BBH A;  5FAI A;  4YQG A;  3NK7 A;  1X7P A;  4MCB A;  2Z0Y A;  4CNF A;  3OIN A;  4E8B A;  3BBD A;  3AIA A;  2QWV A;  4L69 A;  2HA8 A;  5CO4 A;  1Z85 A;  4YVG A;  4IG6 A;  4YPZ A;  2V3J A;  1V6Z A;  4YPW A;  4CNE A;  4X3L A;  3NK6 A;  4YQ8 A;  4YQP A;  4YQ0 A;  4X3M A;  2V3K A;  4YQ4 A;  4YQ6 A;  1TO0 A;  1VHK A;  1NXZ A;  1O6D A;  4RG1 A;  4YQ3 A;  3BBE A;  3E5Y A;  4H3Z A;  4YQD A;  4JAK A;  3IC6 A;  3QUV A;  3KNU A;  4KDZ A;  4YQ1 A;  1V2X A;  3GYQ A;  4YPY A;  4PZK A;  4YQN A;  4J3C A;  4CNG A;  3DCM X;  4YQR A;  3O7B A;  4JAL A;  4YQK A;  4YQ5 A;  2CX8 A;  3N4K A;  3ILK A;  1P9P A;  4YQO A;  3AXZ A;  1UAM A;  4YQ2 A;  1J85 A;  5D9F A;  4YVK A;  2YY8 A;  4YQC A;  4YPX A;  1ZJR A;  4YVI A;  3AI9 X;  1X7O A;  1OY5 A;  5GM8 A;  1NS5 A;  4XBO A;  4YQI A;  1GZ0 A;  4YVH A;  4FAK A;  4YQT A;  4YQ9 A;  3ONP A;  1IPA A;  2EGW A;  4YQA A;  5GMB A;  4YQQ A;  1UAK A;  1UAL A;  3OII A;  5GMC A; 
#chains in the Genus database with same CATH topology
 4YQB A;  3SSX N;  4CND A;  4YQ7 A;  2O3A A;  3L8U A;  3KY7 A;  3SSW N;  4YQS A;  1TRO A;  4YQL A;  1WRT R;  1MXI A;  3KW2 A;  4MCD A;  1VHY A;  1UAJ A;  3IEF A;  2EGV A;  3N4J A;  1TRR A;  3OIJ A;  1ZT9 A;  1VH0 A;  1MI7 R;  3KTY A;  4KGN A;  3KOR A;  2I6D A;  1WRP R;  4MCC A;  4H3Y A;  1K3R A;  4YVJ A;  2QMM A;  4YQJ A;  3BBH A;  5FAI A;  4YQG A;  3NK7 A;  1X7P A;  4MCB A;  2Z0Y A;  1WRS R;  4CNF A;  4E8B A;  3OIN A;  3BBD A;  3AIA A;  2QWV A;  4L69 A;  2HA8 A;  4JWF A;  5CO4 A;  1Z85 A;  4YVG A;  4IG6 A;  4YPZ A;  2V3J A;  4JWG A;  1V6Z A;  4YPW A;  4CNE A;  4X3L A;  3NK6 A;  4YQ8 A;  2XDI A;  4YQP A;  4YQ0 A;  4X3M A;  2V3K A;  4YQ4 A;  4YQ6 A;  1TO0 A;  1VHK A;  1NXZ A;  1O6D A;  4RG1 A;  4YQ3 A;  3BBE A;  3E5Y A;  4H3Z A;  4JWJ A;  3FRW A;  4YQD A;  4JAK A;  3WRP A;  3IC6 A;  3QUV A;  3KNU A;  4KDZ A;  3G1C A;  4YQ1 A;  1V2X A;  4YPY A;  3GYQ A;  4PZK A;  4YQN A;  4J3C A;  4CNG A;  1RCS A;  4YQR A;  3DCM X;  3O7B A;  4JAL A;  4YQK A;  4YQ5 A;  2CX8 A;  2OZ9 R;  3N4K A;  3ILK A;  1P9P A;  4YQO A;  3AXZ A;  1UAM A;  4YQ2 A;  1J85 A;  1CO0 A;  5D9F A;  4YVK A;  4JWH A;  2YY8 A;  4YQC A;  4YPX A;  1ZJR A;  4YVI A;  3AI9 X;  1X7O A;  1OY5 A;  1JHG A;  5GM8 A;  1NS5 A;  4XBO A;  4YQI A;  1GZ0 A;  4YVH A;  4FAK A;  4YQT A;  4YQ9 A;  3ONP A;  1IPA A;  2EGW A;  4YQA A;  5GMB A;  4FMW A;  4YQQ A;  1UAK A;  1UAL A;  3OII A;  5GMC A; 
#chains in the Genus database with same CATH homology
 4YQB A;  4CND A;  4YQ7 A;  2O3A A;  3L8U A;  3KY7 A;  4YQS A;  4YQL A;  1MXI A;  3KW2 A;  4MCD A;  1VHY A;  1UAJ A;  3IEF A;  2EGV A;  3N4J A;  3OIJ A;  1VH0 A;  3KTY A;  4KGN A;  2I6D A;  4MCC A;  4H3Y A;  1K3R A;  4YVJ A;  2QMM A;  4YQJ A;  3BBH A;  5FAI A;  4YQG A;  3NK7 A;  1X7P A;  4MCB A;  2Z0Y A;  4CNF A;  3OIN A;  4E8B A;  3BBD A;  3AIA A;  2QWV A;  4L69 A;  2HA8 A;  4JWF A;  5CO4 A;  1Z85 A;  4YVG A;  4IG6 A;  4YPZ A;  2V3J A;  4JWG A;  1V6Z A;  4YPW A;  4CNE A;  4X3L A;  3NK6 A;  4YQ8 A;  4YQP A;  4YQ0 A;  4X3M A;  2V3K A;  4YQ4 A;  4YQ6 A;  1TO0 A;  1VHK A;  1NXZ A;  1O6D A;  4RG1 A;  4YQ3 A;  3BBE A;  3E5Y A;  4H3Z A;  4JWJ A;  4YQD A;  4JAK A;  3IC6 A;  3QUV A;  3KNU A;  4KDZ A;  4YQ1 A;  1V2X A;  3GYQ A;  4YPY A;  4PZK A;  4YQN A;  4J3C A;  4CNG A;  3DCM X;  4YQR A;  3O7B A;  4JAL A;  4YQK A;  4YQ5 A;  2CX8 A;  3N4K A;  3ILK A;  1P9P A;  4YQO A;  3AXZ A;  1UAM A;  4YQ2 A;  1J85 A;  5D9F A;  4YVK A;  4JWH A;  2YY8 A;  4YQC A;  4YPX A;  1ZJR A;  4YVI A;  3AI9 X;  1X7O A;  1OY5 A;  5GM8 A;  1NS5 A;  4XBO A;  4YQI A;  1GZ0 A;  4YVH A;  4FAK A;  4YQT A;  4YQ9 A;  3ONP A;  1IPA A;  2EGW A;  4YQA A;  5GMB A;  4FMW A;  4YQQ A;  1UAK A;  1UAL A;  3OII A;  5GMC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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