4YQOA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
254
structure length
242
Chain Sequence
GLVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 242
sequence length 254
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqoA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqoA01
1V6ZA 4YQ2A 4YVJA 3AXZA 4YVGA 2YY8A 3ILKA 4YVIA 3GYQA 4YQNA 4JAKA 5D9FA 3DCMX 4H3YA 4YQCA 2EGWA 4YQJA 3OIIA 3KNUA 1OY5A 3IEFA 3BBEA 1MXIA 2CX8A 4L69A 1V2XA 4YQAA 4X3MA 4XBOA 3KY7A 4YQOA 1GZ0A 4YPWA 4CNDA 4YQSA 2O3AA 4YQDA 4YQ6A 4YQPA 1X7OA 4FAKA 3BBHA 1UAKA 4YQTA 2QWVA 4H3ZA 4YQ9A 3ONPA 5GM8A 4RG1A 4CNFA 4YQGA 4YQ8A 2V3KA 3N4JA 1IPAA 1UAJA 2Z0YA 3E5YA 4YPYA 1ZJRA 1NXZA 3NK6A 1VHKA 1J85A 4YQ4A 3AIAA 4YQLA 3BBDA 4KGNA 5GMCA 3IC6A 4YQ0A 2I6DA 4PZKA 3AI9X 4KDZA 1X7PA 5FAIA 3L8UA 3KTYA 4YPXA 4YVHA 4MCDA 4IG6A 4YQBA 1O6DA 4MCCA 4CNEA 3N4KA 4X3LA 4YQQA 5CO4A 4YPZA 3KW2A 3QUVA 2EGVA 4J3CA 4YVKA 4MCBA 1TO0A 4YQKA 4YQ3A 1NS5A 3O7BA 1Z85A 3OINA 2QMMA 1K3RA 4JALA 1VH0A 2V3JA 4YQ5A 1P9PA 1UAMA 4YQ7A 1UALA 5GMBA 4E8BA 4YQIA 3NK7A 1VHYA 4YQRA 3OIJA 4CNGA 2HA8A 4YQ1A
chains in the Genus database with same CATH superfamily
1V6ZA 4YQ2A 4YVJA 3AXZA 4YVGA 2YY8A 3ILKA 4YVIA 3GYQA 3SSXN 4YQNA 4JAKA 5D9FA 1RCSA 3DCMX 4H3YA 2XDIA 4YQCA 2EGWA 4YQJA 3OIIA 3KNUA 1OY5A 3IEFA 2OZ9R 3BBEA 1MXIA 2CX8A 4FMWA 4L69A 1WRPR 3WRPA 1V2XA 1WRSR 4YQAA 1TRRA 4X3MA 4XBOA 3KY7A 4YQOA 1GZ0A 4JWJA 4YPWA 1JHGA 4CNDA 4YQSA 2O3AA 4YQDA 1CO0A 4YQ6A 3SSWN 4YQPA 1X7OA 4JWFA 4FAKA 3BBHA 1UAKA 4YQTA 2QWVA 4H3ZA 4YQ9A 3ONPA 1ZT9A 5GM8A 4RG1A 4CNFA 4YQGA 3FRWA 4YQ8A 2V3KA 3N4JA 1IPAA 1UAJA 2Z0YA 3E5YA 4YPYA 1ZJRA 3KORA 1NXZA 3NK6A 4JWHA 1VHKA 1J85A 4YQ4A 3AIAA 4YQLA 3BBDA 4KGNA 5GMCA 3IC6A 4YQ0A 2I6DA 4PZKA 1WRTR 3AI9X 1MI7R 4KDZA 1X7PA 5FAIA 3L8UA 3KTYA 4YPXA 4YVHA 4MCDA 4IG6A 3G1CA 4YQBA 1O6DA 4MCCA 4CNEA 3N4KA 4X3LA 4YQQA 1TROA 5CO4A 4YPZA 3KW2A 3QUVA 2EGVA 4J3CA 4YVKA 4MCBA 1TO0A 4YQKA 4YQ3A 1NS5A 3O7BA 1Z85A 3OINA 2QMMA 1K3RA 4JALA 1VH0A 2V3JA 4YQ5A 1P9PA 1UAMA 4YQ7A 1UALA 5GMBA 4E8BA 4YQIA 3NK7A 1VHYA 4YQRA 3OIJA 4CNGA 2HA8A 4JWGA 4YQ1A
chains in the Genus database with same CATH topology
1V6ZA 4YQ2A 4YVJA 3AXZA 4YVGA 2YY8A 3ILKA 4YVIA 3GYQA 4YQNA 4JAKA 5D9FA 3DCMX 4H3YA 4YQCA 2EGWA 4YQJA 3OIIA 3KNUA 1OY5A 3IEFA 3BBEA 1MXIA 2CX8A 4FMWA 4L69A 1V2XA 4YQAA 4X3MA 4XBOA 3KY7A 4YQOA 1GZ0A 4JWJA 4YPWA 4CNDA 4YQSA 2O3AA 4YQDA 4YQ6A 4YQPA 1X7OA 4JWFA 4FAKA 3BBHA 1UAKA 4YQTA 2QWVA 4H3ZA 4YQ9A 3ONPA 5GM8A 4RG1A 4CNFA 4YQGA 4YQ8A 2V3KA 3N4JA 1IPAA 1UAJA 2Z0YA 3E5YA 4YPYA 1ZJRA 1NXZA 3NK6A 4JWHA 1VHKA 1J85A 4YQ4A 3AIAA 4YQLA 3BBDA 4KGNA 5GMCA 3IC6A 4YQ0A 2I6DA 4PZKA 3AI9X 4KDZA 1X7PA 5FAIA 3L8UA 3KTYA 4YPXA 4YVHA 4MCDA 4IG6A 4YQBA 1O6DA 4MCCA 4CNEA 3N4KA 4X3LA 4YQQA 5CO4A 4YPZA 3KW2A 3QUVA 2EGVA 4J3CA 4YVKA 4MCBA 1TO0A 4YQKA 4YQ3A 1NS5A 3O7BA 1Z85A 3OINA 2QMMA 1K3RA 4JALA 1VH0A 2V3JA 4YQ5A 1P9PA 1UAMA 4YQ7A 1UALA 5GMBA 4E8BA 4YQIA 3NK7A 1VHYA 4YQRA 3OIJA 4CNGA 2HA8A 4JWGA 4YQ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V6Z A;  4YQ2 A;  4YVJ A;  3AXZ A;  4YVG A;  2YY8 A;  3ILK A;  4YVI A;  3GYQ A;  4YQN A;  4JAK A;  5D9F A;  3DCM X;  4H3Y A;  4YQC A;  2EGW A;  4YQJ A;  3OII A;  3KNU A;  1OY5 A;  3IEF A;  3BBE A;  1MXI A;  2CX8 A;  4L69 A;  1V2X A;  4YQA A;  4X3M A;  4XBO A;  3KY7 A;  4YQO A;  1GZ0 A;  4YPW A;  4CND A;  4YQS A;  2O3A A;  4YQD A;  4YQ6 A;  4YQP A;  1X7O A;  4FAK A;  3BBH A;  1UAK A;  4YQT A;  2QWV A;  4H3Z A;  4YQ9 A;  3ONP A;  5GM8 A;  4RG1 A;  4CNF A;  4YQG A;  4YQ8 A;  2V3K A;  3N4J A;  1IPA A;  1UAJ A;  2Z0Y A;  3E5Y A;  4YPY A;  1ZJR A;  1NXZ A;  3NK6 A;  1VHK A;  1J85 A;  4YQ4 A;  3AIA A;  4YQL A;  3BBD A;  4KGN A;  5GMC A;  3IC6 A;  4YQ0 A;  2I6D A;  4PZK A;  3AI9 X;  4KDZ A;  1X7P A;  5FAI A;  3L8U A;  3KTY A;  4YPX A;  4YVH A;  4MCD A;  4IG6 A;  4YQB A;  1O6D A;  4MCC A;  4CNE A;  3N4K A;  4X3L A;  4YQQ A;  5CO4 A;  4YPZ A;  3KW2 A;  3QUV A;  2EGV A;  4J3C A;  4YVK A;  4MCB A;  1TO0 A;  4YQK A;  4YQ3 A;  1NS5 A;  3O7B A;  1Z85 A;  3OIN A;  2QMM A;  1K3R A;  4JAL A;  1VH0 A;  2V3J A;  4YQ5 A;  1P9P A;  1UAM A;  4YQ7 A;  1UAL A;  5GMB A;  4E8B A;  4YQI A;  3NK7 A;  1VHY A;  4YQR A;  3OIJ A;  4CNG A;  2HA8 A;  4YQ1 A; 
#chains in the Genus database with same CATH topology
 1V6Z A;  4YQ2 A;  4YVJ A;  3AXZ A;  4YVG A;  2YY8 A;  3ILK A;  4YVI A;  3GYQ A;  3SSX N;  4YQN A;  4JAK A;  5D9F A;  1RCS A;  3DCM X;  4H3Y A;  2XDI A;  4YQC A;  2EGW A;  4YQJ A;  3OII A;  3KNU A;  1OY5 A;  3IEF A;  2OZ9 R;  3BBE A;  1MXI A;  2CX8 A;  4FMW A;  4L69 A;  1WRP R;  3WRP A;  1V2X A;  1WRS R;  4YQA A;  1TRR A;  4X3M A;  4XBO A;  3KY7 A;  4YQO A;  1GZ0 A;  4JWJ A;  4YPW A;  1JHG A;  4CND A;  4YQS A;  2O3A A;  4YQD A;  1CO0 A;  4YQ6 A;  3SSW N;  4YQP A;  1X7O A;  4JWF A;  4FAK A;  3BBH A;  1UAK A;  4YQT A;  2QWV A;  4H3Z A;  4YQ9 A;  3ONP A;  1ZT9 A;  5GM8 A;  4RG1 A;  4CNF A;  4YQG A;  3FRW A;  4YQ8 A;  2V3K A;  3N4J A;  1IPA A;  1UAJ A;  2Z0Y A;  3E5Y A;  4YPY A;  1ZJR A;  3KOR A;  1NXZ A;  3NK6 A;  4JWH A;  1VHK A;  1J85 A;  4YQ4 A;  3AIA A;  4YQL A;  3BBD A;  4KGN A;  5GMC A;  3IC6 A;  4YQ0 A;  2I6D A;  4PZK A;  1WRT R;  3AI9 X;  1MI7 R;  4KDZ A;  1X7P A;  5FAI A;  3L8U A;  3KTY A;  4YPX A;  4YVH A;  4MCD A;  4IG6 A;  3G1C A;  4YQB A;  1O6D A;  4MCC A;  4CNE A;  3N4K A;  4X3L A;  4YQQ A;  1TRO A;  5CO4 A;  4YPZ A;  3KW2 A;  3QUV A;  2EGV A;  4J3C A;  4YVK A;  4MCB A;  1TO0 A;  4YQK A;  4YQ3 A;  1NS5 A;  3O7B A;  1Z85 A;  3OIN A;  2QMM A;  1K3R A;  4JAL A;  1VH0 A;  2V3J A;  4YQ5 A;  1P9P A;  1UAM A;  4YQ7 A;  1UAL A;  5GMB A;  4E8B A;  4YQI A;  3NK7 A;  1VHY A;  4YQR A;  3OIJ A;  4CNG A;  2HA8 A;  4JWG A;  4YQ1 A; 
#chains in the Genus database with same CATH homology
 1V6Z A;  4YQ2 A;  4YVJ A;  3AXZ A;  4YVG A;  2YY8 A;  3ILK A;  4YVI A;  3GYQ A;  4YQN A;  4JAK A;  5D9F A;  3DCM X;  4H3Y A;  4YQC A;  2EGW A;  4YQJ A;  3OII A;  3KNU A;  1OY5 A;  3IEF A;  3BBE A;  1MXI A;  2CX8 A;  4FMW A;  4L69 A;  1V2X A;  4YQA A;  4X3M A;  4XBO A;  3KY7 A;  4YQO A;  1GZ0 A;  4JWJ A;  4YPW A;  4CND A;  4YQS A;  2O3A A;  4YQD A;  4YQ6 A;  4YQP A;  1X7O A;  4JWF A;  4FAK A;  3BBH A;  1UAK A;  4YQT A;  2QWV A;  4H3Z A;  4YQ9 A;  3ONP A;  5GM8 A;  4RG1 A;  4CNF A;  4YQG A;  4YQ8 A;  2V3K A;  3N4J A;  1IPA A;  1UAJ A;  2Z0Y A;  3E5Y A;  4YPY A;  1ZJR A;  1NXZ A;  3NK6 A;  4JWH A;  1VHK A;  1J85 A;  4YQ4 A;  3AIA A;  4YQL A;  3BBD A;  4KGN A;  5GMC A;  3IC6 A;  4YQ0 A;  2I6D A;  4PZK A;  3AI9 X;  4KDZ A;  1X7P A;  5FAI A;  3L8U A;  3KTY A;  4YPX A;  4YVH A;  4MCD A;  4IG6 A;  4YQB A;  1O6D A;  4MCC A;  4CNE A;  3N4K A;  4X3L A;  4YQQ A;  5CO4 A;  4YPZ A;  3KW2 A;  3QUV A;  2EGV A;  4J3C A;  4YVK A;  4MCB A;  1TO0 A;  4YQK A;  4YQ3 A;  1NS5 A;  3O7B A;  1Z85 A;  3OIN A;  2QMM A;  1K3R A;  4JAL A;  1VH0 A;  2V3J A;  4YQ5 A;  1P9P A;  1UAM A;  4YQ7 A;  1UAL A;  5GMB A;  4E8B A;  4YQI A;  3NK7 A;  1VHY A;  4YQR A;  3OIJ A;  4CNG A;  2HA8 A;  4JWG A;  4YQ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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