4YQPA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 66
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqpA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqpA01
3OINA 4YQKA 4YPZA 4YVHA 1VH0A 1VHYA 4YQ3A 1UAMA 4YQAA 3OIIA 3DCMX 1X7OA 3GYQA 4YQBA 4CNEA 4YQCA 4YQQA 3E5YA 3NK6A 4H3ZA 4PZKA 1K3RA 3AI9X 1MXIA 4YQLA 4YQ1A 3OIJA 4X3LA 2CX8A 3AIAA 1UAKA 4YQTA 4IG6A 3L8UA 4JAKA 5CO4A 3KNUA 1P9PA 4JALA 4XBOA 3BBHA 3NK7A 4CNGA 2Z0YA 4YVJA 4FAKA 4H3YA 4L69A 4YQ0A 2HA8A 4YQSA 3O7BA 3N4KA 1TO0A 5GMCA 3KY7A 4YVIA 5D9FA 4YQNA 1UALA 4YPYA 4YQ7A 1NS5A 4YQ6A 1X7PA 1ZJRA 3IC6A 4YPWA 5FAIA 1UAJA 4YQRA 2QMMA 1V6ZA 4YQPA 4YVKA 1IPAA 4MCBA 1NXZA 4YQGA 4YQ8A 4YQ9A 1OY5A 4YQIA 2QWVA 4KGNA 2V3KA 3KTYA 4YQ4A 4YQ5A 4MCCA 3ONPA 3N4JA 4KDZA 4YQDA 4CNDA 3IEFA 3BBEA 4CNFA 2EGVA 2O3AA 4YQJA 3ILKA 1VHKA 2I6DA 4YPXA 2EGWA 4J3CA 1V2XA 3AXZA 4E8BA 4YQOA 4YVGA 2V3JA 1Z85A 3KW2A 3BBDA 4YQ2A 4X3MA 5GM8A 5GMBA 1J85A 3QUVA 4MCDA 4RG1A 1O6DA 2YY8A 1GZ0A
chains in the Genus database with same CATH superfamily
3OINA 4YQKA 4YPZA 3G1CA 4YVHA 1VH0A 1VHYA 4JWHA 4YQ3A 1UAMA 4YQAA 3OIIA 3DCMX 2OZ9R 1X7OA 3GYQA 4YQBA 4CNEA 4YQCA 4YQQA 3E5YA 3NK6A 2XDIA 1JHGA 4H3ZA 4PZKA 1K3RA 3AI9X 1MXIA 4JWGA 4YQLA 4YQ1A 3OIJA 4X3LA 2CX8A 3AIAA 1UAKA 4YQTA 4IG6A 3L8UA 4JAKA 5CO4A 3KNUA 3SSWN 1P9PA 4JALA 4XBOA 3BBHA 3NK7A 1RCSA 4CNGA 2Z0YA 4YVJA 3FRWA 4FAKA 4H3YA 4L69A 4YQ0A 2HA8A 4YQSA 3O7BA 3N4KA 1TO0A 5GMCA 3KY7A 4YVIA 5D9FA 4YQNA 1UALA 3SSXN 1WRPR 1WRTR 4YPYA 4YQ7A 1NS5A 4YQ6A 1X7PA 1ZJRA 3IC6A 4YPWA 5FAIA 4JWJA 1UAJA 4YQRA 2QMMA 1V6ZA 4YQPA 1ZT9A 4YVKA 1IPAA 4MCBA 1NXZA 4YQGA 4YQ8A 4YQ9A 3WRPA 1MI7R 1OY5A 4YQIA 2QWVA 4KGNA 2V3KA 4FMWA 3KTYA 4YQ4A 1TRRA 3KORA 4YQ5A 4MCCA 3ONPA 1CO0A 3N4JA 4KDZA 4YQDA 4CNDA 3IEFA 3BBEA 4CNFA 2EGVA 1WRSR 2O3AA 4YQJA 3ILKA 1VHKA 2I6DA 4YPXA 2EGWA 4J3CA 1V2XA 3AXZA 1TROA 4E8BA 4YQOA 4YVGA 2V3JA 1Z85A 3KW2A 4JWFA 3BBDA 4YQ2A 4X3MA 5GM8A 5GMBA 1J85A 3QUVA 4MCDA 4RG1A 1O6DA 2YY8A 1GZ0A
chains in the Genus database with same CATH topology
3OINA 4YQKA 4YPZA 4YVHA 1VH0A 1VHYA 4JWHA 4YQ3A 1UAMA 4YQAA 3OIIA 3DCMX 1X7OA 3GYQA 4YQBA 4CNEA 4YQCA 4YQQA 3E5YA 3NK6A 4H3ZA 4PZKA 1K3RA 3AI9X 1MXIA 4JWGA 4YQLA 4YQ1A 3OIJA 4X3LA 2CX8A 3AIAA 1UAKA 4YQTA 4IG6A 3L8UA 4JAKA 5CO4A 3KNUA 1P9PA 4JALA 4XBOA 3BBHA 3NK7A 4CNGA 2Z0YA 4YVJA 4FAKA 4H3YA 4L69A 4YQ0A 2HA8A 4YQSA 3O7BA 3N4KA 1TO0A 5GMCA 3KY7A 4YVIA 5D9FA 4YQNA 1UALA 4YPYA 4YQ7A 1NS5A 4YQ6A 1X7PA 1ZJRA 3IC6A 4YPWA 5FAIA 4JWJA 1UAJA 4YQRA 2QMMA 1V6ZA 4YQPA 4YVKA 1IPAA 4MCBA 1NXZA 4YQGA 4YQ8A 4YQ9A 1OY5A 4YQIA 2QWVA 4KGNA 2V3KA 4FMWA 3KTYA 4YQ4A 4YQ5A 4MCCA 3ONPA 3N4JA 4KDZA 4YQDA 4CNDA 3IEFA 3BBEA 4CNFA 2EGVA 2O3AA 4YQJA 3ILKA 1VHKA 2I6DA 4YPXA 2EGWA 4J3CA 1V2XA 3AXZA 4E8BA 4YQOA 4YVGA 2V3JA 1Z85A 3KW2A 4JWFA 3BBDA 4YQ2A 4X3MA 5GM8A 5GMBA 1J85A 3QUVA 4MCDA 4RG1A 1O6DA 2YY8A 1GZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OIN A;  4YQK A;  4YPZ A;  4YVH A;  1VH0 A;  1VHY A;  4YQ3 A;  1UAM A;  4YQA A;  3OII A;  3DCM X;  1X7O A;  3GYQ A;  4YQB A;  4CNE A;  4YQC A;  4YQQ A;  3E5Y A;  3NK6 A;  4H3Z A;  4PZK A;  1K3R A;  3AI9 X;  1MXI A;  4YQL A;  4YQ1 A;  3OIJ A;  4X3L A;  2CX8 A;  3AIA A;  1UAK A;  4YQT A;  4IG6 A;  3L8U A;  4JAK A;  5CO4 A;  3KNU A;  1P9P A;  4JAL A;  4XBO A;  3BBH A;  3NK7 A;  4CNG A;  2Z0Y A;  4YVJ A;  4FAK A;  4H3Y A;  4L69 A;  4YQ0 A;  2HA8 A;  4YQS A;  3O7B A;  3N4K A;  1TO0 A;  5GMC A;  3KY7 A;  4YVI A;  5D9F A;  4YQN A;  1UAL A;  4YPY A;  4YQ7 A;  1NS5 A;  4YQ6 A;  1X7P A;  1ZJR A;  3IC6 A;  4YPW A;  5FAI A;  1UAJ A;  4YQR A;  2QMM A;  1V6Z A;  4YQP A;  4YVK A;  1IPA A;  4MCB A;  1NXZ A;  4YQG A;  4YQ8 A;  4YQ9 A;  1OY5 A;  4YQI A;  2QWV A;  4KGN A;  2V3K A;  3KTY A;  4YQ4 A;  4YQ5 A;  4MCC A;  3ONP A;  3N4J A;  4KDZ A;  4YQD A;  4CND A;  3IEF A;  3BBE A;  4CNF A;  2EGV A;  2O3A A;  4YQJ A;  3ILK A;  1VHK A;  2I6D A;  4YPX A;  2EGW A;  4J3C A;  1V2X A;  3AXZ A;  4E8B A;  4YQO A;  4YVG A;  2V3J A;  1Z85 A;  3KW2 A;  3BBD A;  4YQ2 A;  4X3M A;  5GM8 A;  5GMB A;  1J85 A;  3QUV A;  4MCD A;  4RG1 A;  1O6D A;  2YY8 A;  1GZ0 A; 
#chains in the Genus database with same CATH topology
 3OIN A;  4YQK A;  4YPZ A;  3G1C A;  4YVH A;  1VH0 A;  1VHY A;  4JWH A;  4YQ3 A;  1UAM A;  4YQA A;  3OII A;  3DCM X;  2OZ9 R;  1X7O A;  3GYQ A;  4YQB A;  4CNE A;  4YQC A;  4YQQ A;  3E5Y A;  3NK6 A;  2XDI A;  1JHG A;  4H3Z A;  4PZK A;  1K3R A;  3AI9 X;  1MXI A;  4JWG A;  4YQL A;  4YQ1 A;  3OIJ A;  4X3L A;  2CX8 A;  3AIA A;  1UAK A;  4YQT A;  4IG6 A;  3L8U A;  4JAK A;  5CO4 A;  3KNU A;  3SSW N;  1P9P A;  4JAL A;  4XBO A;  3BBH A;  3NK7 A;  1RCS A;  4CNG A;  2Z0Y A;  4YVJ A;  3FRW A;  4FAK A;  4H3Y A;  4L69 A;  4YQ0 A;  2HA8 A;  4YQS A;  3O7B A;  3N4K A;  1TO0 A;  5GMC A;  3KY7 A;  4YVI A;  5D9F A;  4YQN A;  1UAL A;  3SSX N;  1WRP R;  1WRT R;  4YPY A;  4YQ7 A;  1NS5 A;  4YQ6 A;  1X7P A;  1ZJR A;  3IC6 A;  4YPW A;  5FAI A;  4JWJ A;  1UAJ A;  4YQR A;  2QMM A;  1V6Z A;  4YQP A;  1ZT9 A;  4YVK A;  1IPA A;  4MCB A;  1NXZ A;  4YQG A;  4YQ8 A;  4YQ9 A;  3WRP A;  1MI7 R;  1OY5 A;  4YQI A;  2QWV A;  4KGN A;  2V3K A;  4FMW A;  3KTY A;  4YQ4 A;  1TRR A;  3KOR A;  4YQ5 A;  4MCC A;  3ONP A;  1CO0 A;  3N4J A;  4KDZ A;  4YQD A;  4CND A;  3IEF A;  3BBE A;  4CNF A;  2EGV A;  1WRS R;  2O3A A;  4YQJ A;  3ILK A;  1VHK A;  2I6D A;  4YPX A;  2EGW A;  4J3C A;  1V2X A;  3AXZ A;  1TRO A;  4E8B A;  4YQO A;  4YVG A;  2V3J A;  1Z85 A;  3KW2 A;  4JWF A;  3BBD A;  4YQ2 A;  4X3M A;  5GM8 A;  5GMB A;  1J85 A;  3QUV A;  4MCD A;  4RG1 A;  1O6D A;  2YY8 A;  1GZ0 A; 
#chains in the Genus database with same CATH homology
 3OIN A;  4YQK A;  4YPZ A;  4YVH A;  1VH0 A;  1VHY A;  4JWH A;  4YQ3 A;  1UAM A;  4YQA A;  3OII A;  3DCM X;  1X7O A;  3GYQ A;  4YQB A;  4CNE A;  4YQC A;  4YQQ A;  3E5Y A;  3NK6 A;  4H3Z A;  4PZK A;  1K3R A;  3AI9 X;  1MXI A;  4JWG A;  4YQL A;  4YQ1 A;  3OIJ A;  4X3L A;  2CX8 A;  3AIA A;  1UAK A;  4YQT A;  4IG6 A;  3L8U A;  4JAK A;  5CO4 A;  3KNU A;  1P9P A;  4JAL A;  4XBO A;  3BBH A;  3NK7 A;  4CNG A;  2Z0Y A;  4YVJ A;  4FAK A;  4H3Y A;  4L69 A;  4YQ0 A;  2HA8 A;  4YQS A;  3O7B A;  3N4K A;  1TO0 A;  5GMC A;  3KY7 A;  4YVI A;  5D9F A;  4YQN A;  1UAL A;  4YPY A;  4YQ7 A;  1NS5 A;  4YQ6 A;  1X7P A;  1ZJR A;  3IC6 A;  4YPW A;  5FAI A;  4JWJ A;  1UAJ A;  4YQR A;  2QMM A;  1V6Z A;  4YQP A;  4YVK A;  1IPA A;  4MCB A;  1NXZ A;  4YQG A;  4YQ8 A;  4YQ9 A;  1OY5 A;  4YQI A;  2QWV A;  4KGN A;  2V3K A;  4FMW A;  3KTY A;  4YQ4 A;  4YQ5 A;  4MCC A;  3ONP A;  3N4J A;  4KDZ A;  4YQD A;  4CND A;  3IEF A;  3BBE A;  4CNF A;  2EGV A;  2O3A A;  4YQJ A;  3ILK A;  1VHK A;  2I6D A;  4YPX A;  2EGW A;  4J3C A;  1V2X A;  3AXZ A;  4E8B A;  4YQO A;  4YVG A;  2V3J A;  1Z85 A;  3KW2 A;  4JWF A;  3BBD A;  4YQ2 A;  4X3M A;  5GM8 A;  5GMB A;  1J85 A;  3QUV A;  4MCD A;  4RG1 A;  1O6D A;  2YY8 A;  1GZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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