4YQQA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
236
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqqA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqqA01
4YQ3A 2I6DA 3NK7A 4YQ8A 2V3KA 4YPYA 2V3JA 4KGNA 4YQ9A 4YQLA 1Z85A 3KTYA 4YQ7A 5GMBA 1X7PA 4H3ZA 4CNGA 1VHKA 4YQ6A 3KW2A 5GMCA 4L69A 4YQQA 3N4JA 4YVKA 4YVIA 3IEFA 4YQAA 4X3LA 3AIAA 4YQOA 1ZJRA 4YQCA 4FAKA 1UALA 2HA8A 4XBOA 2YY8A 4JALA 4YVJA 4YQ5A 3IC6A 1NS5A 4YPZA 5CO4A 4YVHA 4YQ2A 1GZ0A 2EGVA 5D9FA 4YQ0A 4YQDA 4YQIA 4KDZA 3GYQA 3KNUA 3AI9X 2QWVA 3BBHA 3O7BA 1UAJA 2EGWA 4MCDA 4YQ4A 4MCCA 1J85A 1K3RA 3OIIA 4RG1A 3BBEA 3BBDA 1OY5A 1NXZA 4J3CA 1UAMA 1O6DA 1V6ZA 4CNDA 4YQRA 4YQNA 3KY7A 3OINA 3AXZA 1VHYA 4YQKA 3QUVA 4CNFA 4YQTA 1TO0A 4YQBA 4MCBA 2CX8A 1IPAA 4YQGA 1P9PA 3ONPA 3ILKA 2Z0YA 2O3AA 3L8UA 1UAKA 4CNEA 3N4KA 4YPWA 1V2XA 4YQ1A 4H3YA 5FAIA 3NK6A 4YQSA 1MXIA 5GM8A 4YPXA 4PZKA 4X3MA 4YQJA 1X7OA 2QMMA 4YVGA 4JAKA 3E5YA 1VH0A 4YQPA 4E8BA 3OIJA 3DCMX 4IG6A
chains in the Genus database with same CATH superfamily
4YQ3A 2I6DA 3NK7A 4YQ8A 2V3KA 4YPYA 2V3JA 4KGNA 4YQ9A 4YQLA 1Z85A 3KTYA 4YQ7A 5GMBA 1TROA 1X7PA 4H3ZA 4CNGA 1VHKA 4YQ6A 1JHGA 3KW2A 5GMCA 4JWFA 4L69A 4YQQA 3N4JA 4YVKA 4YVIA 3IEFA 4YQAA 4X3LA 3AIAA 4YQOA 1ZJRA 1WRSR 4YQCA 4FAKA 1UALA 2HA8A 4XBOA 2YY8A 3SSWN 4FMWA 4JALA 4YVJA 2OZ9R 3G1CA 4YQ5A 3IC6A 1NS5A 4JWJA 3KORA 4YPZA 5CO4A 4YVHA 4YQ2A 1GZ0A 2EGVA 4JWGA 5D9FA 4YQ0A 1WRTR 4YQDA 4YQIA 4KDZA 3GYQA 3KNUA 3AI9X 2QWVA 3BBHA 3O7BA 3FRWA 1UAJA 2EGWA 4MCDA 4YQ4A 4MCCA 1J85A 1MI7R 1K3RA 3OIIA 4RG1A 3BBEA 4JWHA 3SSXN 3BBDA 1OY5A 1NXZA 4J3CA 1UAMA 1O6DA 1V6ZA 1RCSA 1TRRA 4CNDA 4YQRA 4YQNA 3KY7A 3OINA 3AXZA 1VHYA 2XDIA 1ZT9A 4YQKA 3QUVA 4CNFA 4YQTA 1TO0A 4YQBA 4MCBA 2CX8A 1IPAA 4YQGA 1P9PA 3ONPA 3ILKA 2Z0YA 3WRPA 2O3AA 3L8UA 1UAKA 4CNEA 3N4KA 4YPWA 1V2XA 4YQ1A 4H3YA 5FAIA 3NK6A 1WRPR 4YQSA 1MXIA 5GM8A 4YPXA 1CO0A 4PZKA 4X3MA 4YQJA 1X7OA 2QMMA 4YVGA 4JAKA 3E5YA 1VH0A 4YQPA 4E8BA 3OIJA 3DCMX 4IG6A
chains in the Genus database with same CATH topology
4YQ3A 2I6DA 3NK7A 4YQ8A 2V3KA 4YPYA 2V3JA 4KGNA 4YQ9A 4YQLA 1Z85A 3KTYA 4YQ7A 5GMBA 1X7PA 4H3ZA 4CNGA 1VHKA 4YQ6A 3KW2A 5GMCA 4JWFA 4L69A 4YQQA 3N4JA 4YVKA 4YVIA 3IEFA 4YQAA 4X3LA 3AIAA 4YQOA 1ZJRA 4YQCA 4FAKA 1UALA 2HA8A 4XBOA 2YY8A 4FMWA 4JALA 4YVJA 4YQ5A 3IC6A 1NS5A 4JWJA 4YPZA 5CO4A 4YVHA 4YQ2A 1GZ0A 2EGVA 4JWGA 5D9FA 4YQ0A 4YQDA 4YQIA 4KDZA 3GYQA 3KNUA 3AI9X 2QWVA 3BBHA 3O7BA 1UAJA 2EGWA 4MCDA 4YQ4A 4MCCA 1J85A 1K3RA 3OIIA 4RG1A 3BBEA 4JWHA 3BBDA 1OY5A 1NXZA 4J3CA 1UAMA 1O6DA 1V6ZA 4CNDA 4YQRA 4YQNA 3KY7A 3OINA 3AXZA 1VHYA 4YQKA 3QUVA 4CNFA 4YQTA 1TO0A 4YQBA 4MCBA 2CX8A 1IPAA 4YQGA 1P9PA 3ONPA 3ILKA 2Z0YA 2O3AA 3L8UA 1UAKA 4CNEA 3N4KA 4YPWA 1V2XA 4YQ1A 4H3YA 5FAIA 3NK6A 4YQSA 1MXIA 5GM8A 4YPXA 4PZKA 4X3MA 4YQJA 1X7OA 2QMMA 4YVGA 4JAKA 3E5YA 1VH0A 4YQPA 4E8BA 3OIJA 3DCMX 4IG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ3 A;  2I6D A;  3NK7 A;  4YQ8 A;  2V3K A;  4YPY A;  2V3J A;  4KGN A;  4YQ9 A;  4YQL A;  1Z85 A;  3KTY A;  4YQ7 A;  5GMB A;  1X7P A;  4H3Z A;  4CNG A;  1VHK A;  4YQ6 A;  3KW2 A;  5GMC A;  4L69 A;  4YQQ A;  3N4J A;  4YVK A;  4YVI A;  3IEF A;  4YQA A;  4X3L A;  3AIA A;  4YQO A;  1ZJR A;  4YQC A;  4FAK A;  1UAL A;  2HA8 A;  4XBO A;  2YY8 A;  4JAL A;  4YVJ A;  4YQ5 A;  3IC6 A;  1NS5 A;  4YPZ A;  5CO4 A;  4YVH A;  4YQ2 A;  1GZ0 A;  2EGV A;  5D9F A;  4YQ0 A;  4YQD A;  4YQI A;  4KDZ A;  3GYQ A;  3KNU A;  3AI9 X;  2QWV A;  3BBH A;  3O7B A;  1UAJ A;  2EGW A;  4MCD A;  4YQ4 A;  4MCC A;  1J85 A;  1K3R A;  3OII A;  4RG1 A;  3BBE A;  3BBD A;  1OY5 A;  1NXZ A;  4J3C A;  1UAM A;  1O6D A;  1V6Z A;  4CND A;  4YQR A;  4YQN A;  3KY7 A;  3OIN A;  3AXZ A;  1VHY A;  4YQK A;  3QUV A;  4CNF A;  4YQT A;  1TO0 A;  4YQB A;  4MCB A;  2CX8 A;  1IPA A;  4YQG A;  1P9P A;  3ONP A;  3ILK A;  2Z0Y A;  2O3A A;  3L8U A;  1UAK A;  4CNE A;  3N4K A;  4YPW A;  1V2X A;  4YQ1 A;  4H3Y A;  5FAI A;  3NK6 A;  4YQS A;  1MXI A;  5GM8 A;  4YPX A;  4PZK A;  4X3M A;  4YQJ A;  1X7O A;  2QMM A;  4YVG A;  4JAK A;  3E5Y A;  1VH0 A;  4YQP A;  4E8B A;  3OIJ A;  3DCM X;  4IG6 A; 
#chains in the Genus database with same CATH topology
 4YQ3 A;  2I6D A;  3NK7 A;  4YQ8 A;  2V3K A;  4YPY A;  2V3J A;  4KGN A;  4YQ9 A;  4YQL A;  1Z85 A;  3KTY A;  4YQ7 A;  5GMB A;  1TRO A;  1X7P A;  4H3Z A;  4CNG A;  1VHK A;  4YQ6 A;  1JHG A;  3KW2 A;  5GMC A;  4JWF A;  4L69 A;  4YQQ A;  3N4J A;  4YVK A;  4YVI A;  3IEF A;  4YQA A;  4X3L A;  3AIA A;  4YQO A;  1ZJR A;  1WRS R;  4YQC A;  4FAK A;  1UAL A;  2HA8 A;  4XBO A;  2YY8 A;  3SSW N;  4FMW A;  4JAL A;  4YVJ A;  2OZ9 R;  3G1C A;  4YQ5 A;  3IC6 A;  1NS5 A;  4JWJ A;  3KOR A;  4YPZ A;  5CO4 A;  4YVH A;  4YQ2 A;  1GZ0 A;  2EGV A;  4JWG A;  5D9F A;  4YQ0 A;  1WRT R;  4YQD A;  4YQI A;  4KDZ A;  3GYQ A;  3KNU A;  3AI9 X;  2QWV A;  3BBH A;  3O7B A;  3FRW A;  1UAJ A;  2EGW A;  4MCD A;  4YQ4 A;  4MCC A;  1J85 A;  1MI7 R;  1K3R A;  3OII A;  4RG1 A;  3BBE A;  4JWH A;  3SSX N;  3BBD A;  1OY5 A;  1NXZ A;  4J3C A;  1UAM A;  1O6D A;  1V6Z A;  1RCS A;  1TRR A;  4CND A;  4YQR A;  4YQN A;  3KY7 A;  3OIN A;  3AXZ A;  1VHY A;  2XDI A;  1ZT9 A;  4YQK A;  3QUV A;  4CNF A;  4YQT A;  1TO0 A;  4YQB A;  4MCB A;  2CX8 A;  1IPA A;  4YQG A;  1P9P A;  3ONP A;  3ILK A;  2Z0Y A;  3WRP A;  2O3A A;  3L8U A;  1UAK A;  4CNE A;  3N4K A;  4YPW A;  1V2X A;  4YQ1 A;  4H3Y A;  5FAI A;  3NK6 A;  1WRP R;  4YQS A;  1MXI A;  5GM8 A;  4YPX A;  1CO0 A;  4PZK A;  4X3M A;  4YQJ A;  1X7O A;  2QMM A;  4YVG A;  4JAK A;  3E5Y A;  1VH0 A;  4YQP A;  4E8B A;  3OIJ A;  3DCM X;  4IG6 A; 
#chains in the Genus database with same CATH homology
 4YQ3 A;  2I6D A;  3NK7 A;  4YQ8 A;  2V3K A;  4YPY A;  2V3J A;  4KGN A;  4YQ9 A;  4YQL A;  1Z85 A;  3KTY A;  4YQ7 A;  5GMB A;  1X7P A;  4H3Z A;  4CNG A;  1VHK A;  4YQ6 A;  3KW2 A;  5GMC A;  4JWF A;  4L69 A;  4YQQ A;  3N4J A;  4YVK A;  4YVI A;  3IEF A;  4YQA A;  4X3L A;  3AIA A;  4YQO A;  1ZJR A;  4YQC A;  4FAK A;  1UAL A;  2HA8 A;  4XBO A;  2YY8 A;  4FMW A;  4JAL A;  4YVJ A;  4YQ5 A;  3IC6 A;  1NS5 A;  4JWJ A;  4YPZ A;  5CO4 A;  4YVH A;  4YQ2 A;  1GZ0 A;  2EGV A;  4JWG A;  5D9F A;  4YQ0 A;  4YQD A;  4YQI A;  4KDZ A;  3GYQ A;  3KNU A;  3AI9 X;  2QWV A;  3BBH A;  3O7B A;  1UAJ A;  2EGW A;  4MCD A;  4YQ4 A;  4MCC A;  1J85 A;  1K3R A;  3OII A;  4RG1 A;  3BBE A;  4JWH A;  3BBD A;  1OY5 A;  1NXZ A;  4J3C A;  1UAM A;  1O6D A;  1V6Z A;  4CND A;  4YQR A;  4YQN A;  3KY7 A;  3OIN A;  3AXZ A;  1VHY A;  4YQK A;  3QUV A;  4CNF A;  4YQT A;  1TO0 A;  4YQB A;  4MCB A;  2CX8 A;  1IPA A;  4YQG A;  1P9P A;  3ONP A;  3ILK A;  2Z0Y A;  2O3A A;  3L8U A;  1UAK A;  4CNE A;  3N4K A;  4YPW A;  1V2X A;  4YQ1 A;  4H3Y A;  5FAI A;  3NK6 A;  4YQS A;  1MXI A;  5GM8 A;  4YPX A;  4PZK A;  4X3M A;  4YQJ A;  1X7O A;  2QMM A;  4YVG A;  4JAK A;  3E5Y A;  1VH0 A;  4YQP A;  4E8B A;  3OIJ A;  3DCM X;  4IG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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