4YQQA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
236
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 236
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqqA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqqA01
4H3YA 4YVHA 4YPXA 3KTYA 1VHYA 3KY7A 1UAJA 4YQKA 4YPZA 2QMMA 1UAKA 4H3ZA 4YQ8A 2QWVA 3ILKA 4YQGA 4YQ4A 4YQNA 4YQAA 4XBOA 4YQ9A 3BBHA 4YQQA 3IEFA 3AXZA 1O6DA 1V2XA 2O3AA 3OIJA 4YQJA 4YQLA 5D9FA 4YVIA 2CX8A 3N4JA 4YQ6A 4J3CA 3BBDA 3IC6A 4IG6A 4YQ0A 4YQ7A 4YQ1A 4FAKA 3KNUA 1GZ0A 1TO0A 1V6ZA 1X7OA 3OIIA 4PZKA 4JAKA 4KDZA 2Z0YA 4CNFA 4X3MA 2I6DA 4MCCA 5GMBA 3GYQA 3NK6A 5GM8A 1J85A 4RG1A 1MXIA 4YPWA 4YQ2A 2HA8A 4MCBA 4MCDA 4YQPA 3KW2A 5CO4A 4X3LA 4YPYA 4YQBA 5FAIA 3ONPA 2EGVA 4L69A 4YQ5A 1ZJRA 4YQIA 4YVGA 3OINA 3L8UA 1VH0A 3N4KA 3NK7A 1OY5A 1VHKA 3BBEA 4E8BA 4CNDA 4YVJA 5GMCA 1P9PA 4YQCA 1IPAA 3QUVA 4YQSA 3O7BA 4YQTA 1NXZA 1K3RA 1X7PA 4CNGA 3AI9X 4YVKA 4YQ3A 3AIAA 1UALA 1Z85A 2YY8A 2V3KA 3E5YA 3DCMX 1UAMA 4YQRA 2EGWA 4KGNA 4JALA 1NS5A 4YQOA 2V3JA 4YQDA 4CNEA
chains in the Genus database with same CATH superfamily
4H3YA 1TROA 4JWFA 4YVHA 4JWGA 4YPXA 3KTYA 3WRPA 1VHYA 3KY7A 1UAJA 4YQKA 4YPZA 2QMMA 1UAKA 4H3ZA 4YQ8A 1WRPR 2QWVA 3ILKA 4YQGA 4YQ4A 4YQNA 4YQAA 4FMWA 4XBOA 4YQ9A 3BBHA 1RCSA 4YQQA 3IEFA 3AXZA 1O6DA 1V2XA 2O3AA 3OIJA 3FRWA 4YQJA 4YQLA 5D9FA 4YVIA 2CX8A 3N4JA 2OZ9R 1CO0A 4YQ6A 4J3CA 3BBDA 3IC6A 4IG6A 4YQ0A 3KORA 4YQ7A 1WRSR 4YQ1A 4FAKA 1TRRA 3KNUA 1GZ0A 1TO0A 1V6ZA 1X7OA 3OIIA 4PZKA 4JAKA 4KDZA 2Z0YA 4CNFA 4X3MA 2I6DA 4MCCA 5GMBA 3GYQA 3NK6A 5GM8A 1J85A 4RG1A 1MXIA 4YPWA 4YQ2A 2HA8A 1WRTR 4MCBA 4MCDA 2XDIA 4YQPA 3KW2A 5CO4A 4JWHA 4X3LA 4YPYA 4YQBA 5FAIA 3ONPA 2EGVA 4L69A 4YQ5A 1ZJRA 4YQIA 1MI7R 4YVGA 3OINA 3L8UA 1VH0A 3N4KA 3NK7A 4JWJA 1OY5A 1VHKA 3BBEA 4E8BA 4CNDA 4YVJA 1JHGA 5GMCA 1P9PA 4YQCA 1IPAA 3QUVA 4YQSA 3SSWN 3O7BA 4YQTA 3SSXN 1NXZA 1K3RA 1X7PA 4CNGA 3AI9X 4YVKA 4YQ3A 3AIAA 1ZT9A 1UALA 1Z85A 2YY8A 2V3KA 3E5YA 3DCMX 1UAMA 4YQRA 2EGWA 4KGNA 4JALA 3G1CA 1NS5A 4YQOA 2V3JA 4YQDA 4CNEA
chains in the Genus database with same CATH topology
4H3YA 4JWFA 4YVHA 4JWGA 4YPXA 3KTYA 1VHYA 3KY7A 1UAJA 4YQKA 4YPZA 2QMMA 1UAKA 4H3ZA 4YQ8A 2QWVA 3ILKA 4YQGA 4YQ4A 4YQNA 4YQAA 4FMWA 4XBOA 4YQ9A 3BBHA 4YQQA 3IEFA 3AXZA 1O6DA 1V2XA 2O3AA 3OIJA 4YQJA 4YQLA 5D9FA 4YVIA 2CX8A 3N4JA 4YQ6A 4J3CA 3BBDA 3IC6A 4IG6A 4YQ0A 4YQ7A 4YQ1A 4FAKA 3KNUA 1GZ0A 1TO0A 1V6ZA 1X7OA 3OIIA 4PZKA 4JAKA 4KDZA 2Z0YA 4CNFA 4X3MA 2I6DA 4MCCA 5GMBA 3GYQA 3NK6A 5GM8A 1J85A 4RG1A 1MXIA 4YPWA 4YQ2A 2HA8A 4MCBA 4MCDA 4YQPA 3KW2A 5CO4A 4JWHA 4X3LA 4YPYA 4YQBA 5FAIA 3ONPA 2EGVA 4L69A 4YQ5A 1ZJRA 4YQIA 4YVGA 3OINA 3L8UA 1VH0A 3N4KA 3NK7A 4JWJA 1OY5A 1VHKA 3BBEA 4E8BA 4CNDA 4YVJA 5GMCA 1P9PA 4YQCA 1IPAA 3QUVA 4YQSA 3O7BA 4YQTA 1NXZA 1K3RA 1X7PA 4CNGA 3AI9X 4YVKA 4YQ3A 3AIAA 1UALA 1Z85A 2YY8A 2V3KA 3E5YA 3DCMX 1UAMA 4YQRA 2EGWA 4KGNA 4JALA 1NS5A 4YQOA 2V3JA 4YQDA 4CNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H3Y A;  4YVH A;  4YPX A;  3KTY A;  1VHY A;  3KY7 A;  1UAJ A;  4YQK A;  4YPZ A;  2QMM A;  1UAK A;  4H3Z A;  4YQ8 A;  2QWV A;  3ILK A;  4YQG A;  4YQ4 A;  4YQN A;  4YQA A;  4XBO A;  4YQ9 A;  3BBH A;  4YQQ A;  3IEF A;  3AXZ A;  1O6D A;  1V2X A;  2O3A A;  3OIJ A;  4YQJ A;  4YQL A;  5D9F A;  4YVI A;  2CX8 A;  3N4J A;  4YQ6 A;  4J3C A;  3BBD A;  3IC6 A;  4IG6 A;  4YQ0 A;  4YQ7 A;  4YQ1 A;  4FAK A;  3KNU A;  1GZ0 A;  1TO0 A;  1V6Z A;  1X7O A;  3OII A;  4PZK A;  4JAK A;  4KDZ A;  2Z0Y A;  4CNF A;  4X3M A;  2I6D A;  4MCC A;  5GMB A;  3GYQ A;  3NK6 A;  5GM8 A;  1J85 A;  4RG1 A;  1MXI A;  4YPW A;  4YQ2 A;  2HA8 A;  4MCB A;  4MCD A;  4YQP A;  3KW2 A;  5CO4 A;  4X3L A;  4YPY A;  4YQB A;  5FAI A;  3ONP A;  2EGV A;  4L69 A;  4YQ5 A;  1ZJR A;  4YQI A;  4YVG A;  3OIN A;  3L8U A;  1VH0 A;  3N4K A;  3NK7 A;  1OY5 A;  1VHK A;  3BBE A;  4E8B A;  4CND A;  4YVJ A;  5GMC A;  1P9P A;  4YQC A;  1IPA A;  3QUV A;  4YQS A;  3O7B A;  4YQT A;  1NXZ A;  1K3R A;  1X7P A;  4CNG A;  3AI9 X;  4YVK A;  4YQ3 A;  3AIA A;  1UAL A;  1Z85 A;  2YY8 A;  2V3K A;  3E5Y A;  3DCM X;  1UAM A;  4YQR A;  2EGW A;  4KGN A;  4JAL A;  1NS5 A;  4YQO A;  2V3J A;  4YQD A;  4CNE A; 
#chains in the Genus database with same CATH topology
 4H3Y A;  1TRO A;  4JWF A;  4YVH A;  4JWG A;  4YPX A;  3KTY A;  3WRP A;  1VHY A;  3KY7 A;  1UAJ A;  4YQK A;  4YPZ A;  2QMM A;  1UAK A;  4H3Z A;  4YQ8 A;  1WRP R;  2QWV A;  3ILK A;  4YQG A;  4YQ4 A;  4YQN A;  4YQA A;  4FMW A;  4XBO A;  4YQ9 A;  3BBH A;  1RCS A;  4YQQ A;  3IEF A;  3AXZ A;  1O6D A;  1V2X A;  2O3A A;  3OIJ A;  3FRW A;  4YQJ A;  4YQL A;  5D9F A;  4YVI A;  2CX8 A;  3N4J A;  2OZ9 R;  1CO0 A;  4YQ6 A;  4J3C A;  3BBD A;  3IC6 A;  4IG6 A;  4YQ0 A;  3KOR A;  4YQ7 A;  1WRS R;  4YQ1 A;  4FAK A;  1TRR A;  3KNU A;  1GZ0 A;  1TO0 A;  1V6Z A;  1X7O A;  3OII A;  4PZK A;  4JAK A;  4KDZ A;  2Z0Y A;  4CNF A;  4X3M A;  2I6D A;  4MCC A;  5GMB A;  3GYQ A;  3NK6 A;  5GM8 A;  1J85 A;  4RG1 A;  1MXI A;  4YPW A;  4YQ2 A;  2HA8 A;  1WRT R;  4MCB A;  4MCD A;  2XDI A;  4YQP A;  3KW2 A;  5CO4 A;  4JWH A;  4X3L A;  4YPY A;  4YQB A;  5FAI A;  3ONP A;  2EGV A;  4L69 A;  4YQ5 A;  1ZJR A;  4YQI A;  1MI7 R;  4YVG A;  3OIN A;  3L8U A;  1VH0 A;  3N4K A;  3NK7 A;  4JWJ A;  1OY5 A;  1VHK A;  3BBE A;  4E8B A;  4CND A;  4YVJ A;  1JHG A;  5GMC A;  1P9P A;  4YQC A;  1IPA A;  3QUV A;  4YQS A;  3SSW N;  3O7B A;  4YQT A;  3SSX N;  1NXZ A;  1K3R A;  1X7P A;  4CNG A;  3AI9 X;  4YVK A;  4YQ3 A;  3AIA A;  1ZT9 A;  1UAL A;  1Z85 A;  2YY8 A;  2V3K A;  3E5Y A;  3DCM X;  1UAM A;  4YQR A;  2EGW A;  4KGN A;  4JAL A;  3G1C A;  1NS5 A;  4YQO A;  2V3J A;  4YQD A;  4CNE A; 
#chains in the Genus database with same CATH homology
 4H3Y A;  4JWF A;  4YVH A;  4JWG A;  4YPX A;  3KTY A;  1VHY A;  3KY7 A;  1UAJ A;  4YQK A;  4YPZ A;  2QMM A;  1UAK A;  4H3Z A;  4YQ8 A;  2QWV A;  3ILK A;  4YQG A;  4YQ4 A;  4YQN A;  4YQA A;  4FMW A;  4XBO A;  4YQ9 A;  3BBH A;  4YQQ A;  3IEF A;  3AXZ A;  1O6D A;  1V2X A;  2O3A A;  3OIJ A;  4YQJ A;  4YQL A;  5D9F A;  4YVI A;  2CX8 A;  3N4J A;  4YQ6 A;  4J3C A;  3BBD A;  3IC6 A;  4IG6 A;  4YQ0 A;  4YQ7 A;  4YQ1 A;  4FAK A;  3KNU A;  1GZ0 A;  1TO0 A;  1V6Z A;  1X7O A;  3OII A;  4PZK A;  4JAK A;  4KDZ A;  2Z0Y A;  4CNF A;  4X3M A;  2I6D A;  4MCC A;  5GMB A;  3GYQ A;  3NK6 A;  5GM8 A;  1J85 A;  4RG1 A;  1MXI A;  4YPW A;  4YQ2 A;  2HA8 A;  4MCB A;  4MCD A;  4YQP A;  3KW2 A;  5CO4 A;  4JWH A;  4X3L A;  4YPY A;  4YQB A;  5FAI A;  3ONP A;  2EGV A;  4L69 A;  4YQ5 A;  1ZJR A;  4YQI A;  4YVG A;  3OIN A;  3L8U A;  1VH0 A;  3N4K A;  3NK7 A;  4JWJ A;  1OY5 A;  1VHK A;  3BBE A;  4E8B A;  4CND A;  4YVJ A;  5GMC A;  1P9P A;  4YQC A;  1IPA A;  3QUV A;  4YQS A;  3O7B A;  4YQT A;  1NXZ A;  1K3R A;  1X7P A;  4CNG A;  3AI9 X;  4YVK A;  4YQ3 A;  3AIA A;  1UAL A;  1Z85 A;  2YY8 A;  2V3K A;  3E5Y A;  3DCM X;  1UAM A;  4YQR A;  2EGW A;  4KGN A;  4JAL A;  1NS5 A;  4YQO A;  2V3J A;  4YQD A;  4CNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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