4YQSA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
248
structure length
237
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 237
sequence length 248
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqsA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqsA01
1VH0A 3AI9X 4YPYA 4YQCA 4MCCA 4YQSA 4YQTA 3KW2A 3KNUA 1O6DA 4YQJA 4YQ1A 3ONPA 4PZKA 4YQ8A 4YQAA 3GYQA 4CNEA 4YQGA 4YQ5A 1MXIA 3E5YA 4CNGA 3OINA 1VHKA 4YPZA 1ZJRA 3N4JA 2V3KA 5GMCA 3IEFA 4KDZA 1GZ0A 4E8BA 4YQKA 3DCMX 3AIAA 4YQQA 5D9FA 4YQDA 2QWVA 4YVJA 1J85A 3QUVA 4YQ2A 3L8UA 1V2XA 4YQ4A 3KTYA 4YVIA 1P9PA 4YVGA 3BBDA 3OIJA 1UAMA 4YVHA 4YQ6A 2YY8A 4YQ0A 3OIIA 2Z0YA 4XBOA 1X7PA 4MCBA 4YVKA 1V6ZA 3BBHA 4KGNA 3NK6A 2EGWA 4YPXA 4YQ9A 4CNFA 4X3LA 2CX8A 1Z85A 2O3AA 1UAJA 5GM8A 4FAKA 1NS5A 5GMBA 4YQBA 4J3CA 4H3YA 4YQPA 5CO4A 4YQ7A 2I6DA 4H3ZA 1OY5A 2V3JA 3AXZA 4RG1A 1NXZA 4L69A 4YQNA 3O7BA 4YQOA 4IG6A 4YQIA 2HA8A 4YQLA 1IPAA 1VHYA 3KY7A 3N4KA 4X3MA 4YQ3A 3ILKA 2QMMA 1K3RA 4YQRA 1X7OA 4JALA 4JAKA 1TO0A 4MCDA 3NK7A 1UALA 2EGVA 1UAKA 4CNDA 5FAIA 4YPWA 3BBEA 3IC6A
chains in the Genus database with same CATH superfamily
1VH0A 1CO0A 3AI9X 4YPYA 4YQCA 4MCCA 4YQSA 4YQTA 3KW2A 3KNUA 1O6DA 4YQJA 4JWFA 4YQ1A 3ONPA 4PZKA 2XDIA 4YQ8A 4YQAA 3GYQA 4JWJA 4CNEA 4YQGA 4YQ5A 1MXIA 3E5YA 4CNGA 3OINA 1VHKA 4YPZA 1ZJRA 3N4JA 2V3KA 5GMCA 3IEFA 4KDZA 1GZ0A 4E8BA 4YQKA 3DCMX 3SSXN 3AIAA 4YQQA 5D9FA 4YQDA 2QWVA 4YVJA 1J85A 3QUVA 4YQ2A 3L8UA 1V2XA 4YQ4A 1RCSA 3KTYA 4JWHA 4YVIA 1P9PA 4YVGA 3BBDA 3OIJA 1WRPR 1UAMA 4YVHA 4YQ6A 2YY8A 4YQ0A 3OIIA 2Z0YA 4XBOA 1X7PA 4MCBA 4YVKA 1V6ZA 3BBHA 4KGNA 3NK6A 2EGWA 4YPXA 4YQ9A 4CNFA 4X3LA 2CX8A 1Z85A 2O3AA 1UAJA 5GM8A 4FAKA 1NS5A 5GMBA 4YQBA 1ZT9A 4J3CA 4H3YA 4YQPA 1TRRA 5CO4A 4YQ7A 2I6DA 3FRWA 3WRPA 4H3ZA 1OY5A 2V3JA 3AXZA 4RG1A 1NXZA 4L69A 4YQNA 3O7BA 4YQOA 4IG6A 4YQIA 2HA8A 4YQLA 1IPAA 1VHYA 3KY7A 3SSWN 4JWGA 3N4KA 4X3MA 4YQ3A 3ILKA 3G1CA 3KORA 2QMMA 1K3RA 4YQRA 1X7OA 4JALA 4JAKA 1TO0A 4MCDA 1JHGA 1WRTR 1MI7R 4FMWA 3NK7A 1UALA 2EGVA 1UAKA 4CNDA 5FAIA 4YPWA 3BBEA 1WRSR 1TROA 2OZ9R 3IC6A
chains in the Genus database with same CATH topology
1VH0A 3AI9X 4YPYA 4YQCA 4MCCA 4YQSA 4YQTA 3KW2A 3KNUA 1O6DA 4YQJA 4JWFA 4YQ1A 3ONPA 4PZKA 4YQ8A 4YQAA 3GYQA 4JWJA 4CNEA 4YQGA 4YQ5A 1MXIA 3E5YA 4CNGA 3OINA 1VHKA 4YPZA 1ZJRA 3N4JA 2V3KA 5GMCA 3IEFA 4KDZA 1GZ0A 4E8BA 4YQKA 3DCMX 3AIAA 4YQQA 5D9FA 4YQDA 2QWVA 4YVJA 1J85A 3QUVA 4YQ2A 3L8UA 1V2XA 4YQ4A 3KTYA 4JWHA 4YVIA 1P9PA 4YVGA 3BBDA 3OIJA 1UAMA 4YVHA 4YQ6A 2YY8A 4YQ0A 3OIIA 2Z0YA 4XBOA 1X7PA 4MCBA 4YVKA 1V6ZA 3BBHA 4KGNA 3NK6A 2EGWA 4YPXA 4YQ9A 4CNFA 4X3LA 2CX8A 1Z85A 2O3AA 1UAJA 5GM8A 4FAKA 1NS5A 5GMBA 4YQBA 4J3CA 4H3YA 4YQPA 5CO4A 4YQ7A 2I6DA 4H3ZA 1OY5A 2V3JA 3AXZA 4RG1A 1NXZA 4L69A 4YQNA 3O7BA 4YQOA 4IG6A 4YQIA 2HA8A 4YQLA 1IPAA 1VHYA 3KY7A 4JWGA 3N4KA 4X3MA 4YQ3A 3ILKA 2QMMA 1K3RA 4YQRA 1X7OA 4JALA 4JAKA 1TO0A 4MCDA 4FMWA 3NK7A 1UALA 2EGVA 1UAKA 4CNDA 5FAIA 4YPWA 3BBEA 3IC6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VH0 A;  3AI9 X;  4YPY A;  4YQC A;  4MCC A;  4YQS A;  4YQT A;  3KW2 A;  3KNU A;  1O6D A;  4YQJ A;  4YQ1 A;  3ONP A;  4PZK A;  4YQ8 A;  4YQA A;  3GYQ A;  4CNE A;  4YQG A;  4YQ5 A;  1MXI A;  3E5Y A;  4CNG A;  3OIN A;  1VHK A;  4YPZ A;  1ZJR A;  3N4J A;  2V3K A;  5GMC A;  3IEF A;  4KDZ A;  1GZ0 A;  4E8B A;  4YQK A;  3DCM X;  3AIA A;  4YQQ A;  5D9F A;  4YQD A;  2QWV A;  4YVJ A;  1J85 A;  3QUV A;  4YQ2 A;  3L8U A;  1V2X A;  4YQ4 A;  3KTY A;  4YVI A;  1P9P A;  4YVG A;  3BBD A;  3OIJ A;  1UAM A;  4YVH A;  4YQ6 A;  2YY8 A;  4YQ0 A;  3OII A;  2Z0Y A;  4XBO A;  1X7P A;  4MCB A;  4YVK A;  1V6Z A;  3BBH A;  4KGN A;  3NK6 A;  2EGW A;  4YPX A;  4YQ9 A;  4CNF A;  4X3L A;  2CX8 A;  1Z85 A;  2O3A A;  1UAJ A;  5GM8 A;  4FAK A;  1NS5 A;  5GMB A;  4YQB A;  4J3C A;  4H3Y A;  4YQP A;  5CO4 A;  4YQ7 A;  2I6D A;  4H3Z A;  1OY5 A;  2V3J A;  3AXZ A;  4RG1 A;  1NXZ A;  4L69 A;  4YQN A;  3O7B A;  4YQO A;  4IG6 A;  4YQI A;  2HA8 A;  4YQL A;  1IPA A;  1VHY A;  3KY7 A;  3N4K A;  4X3M A;  4YQ3 A;  3ILK A;  2QMM A;  1K3R A;  4YQR A;  1X7O A;  4JAL A;  4JAK A;  1TO0 A;  4MCD A;  3NK7 A;  1UAL A;  2EGV A;  1UAK A;  4CND A;  5FAI A;  4YPW A;  3BBE A;  3IC6 A; 
#chains in the Genus database with same CATH topology
 1VH0 A;  1CO0 A;  3AI9 X;  4YPY A;  4YQC A;  4MCC A;  4YQS A;  4YQT A;  3KW2 A;  3KNU A;  1O6D A;  4YQJ A;  4JWF A;  4YQ1 A;  3ONP A;  4PZK A;  2XDI A;  4YQ8 A;  4YQA A;  3GYQ A;  4JWJ A;  4CNE A;  4YQG A;  4YQ5 A;  1MXI A;  3E5Y A;  4CNG A;  3OIN A;  1VHK A;  4YPZ A;  1ZJR A;  3N4J A;  2V3K A;  5GMC A;  3IEF A;  4KDZ A;  1GZ0 A;  4E8B A;  4YQK A;  3DCM X;  3SSX N;  3AIA A;  4YQQ A;  5D9F A;  4YQD A;  2QWV A;  4YVJ A;  1J85 A;  3QUV A;  4YQ2 A;  3L8U A;  1V2X A;  4YQ4 A;  1RCS A;  3KTY A;  4JWH A;  4YVI A;  1P9P A;  4YVG A;  3BBD A;  3OIJ A;  1WRP R;  1UAM A;  4YVH A;  4YQ6 A;  2YY8 A;  4YQ0 A;  3OII A;  2Z0Y A;  4XBO A;  1X7P A;  4MCB A;  4YVK A;  1V6Z A;  3BBH A;  4KGN A;  3NK6 A;  2EGW A;  4YPX A;  4YQ9 A;  4CNF A;  4X3L A;  2CX8 A;  1Z85 A;  2O3A A;  1UAJ A;  5GM8 A;  4FAK A;  1NS5 A;  5GMB A;  4YQB A;  1ZT9 A;  4J3C A;  4H3Y A;  4YQP A;  1TRR A;  5CO4 A;  4YQ7 A;  2I6D A;  3FRW A;  3WRP A;  4H3Z A;  1OY5 A;  2V3J A;  3AXZ A;  4RG1 A;  1NXZ A;  4L69 A;  4YQN A;  3O7B A;  4YQO A;  4IG6 A;  4YQI A;  2HA8 A;  4YQL A;  1IPA A;  1VHY A;  3KY7 A;  3SSW N;  4JWG A;  3N4K A;  4X3M A;  4YQ3 A;  3ILK A;  3G1C A;  3KOR A;  2QMM A;  1K3R A;  4YQR A;  1X7O A;  4JAL A;  4JAK A;  1TO0 A;  4MCD A;  1JHG A;  1WRT R;  1MI7 R;  4FMW A;  3NK7 A;  1UAL A;  2EGV A;  1UAK A;  4CND A;  5FAI A;  4YPW A;  3BBE A;  1WRS R;  1TRO A;  2OZ9 R;  3IC6 A; 
#chains in the Genus database with same CATH homology
 1VH0 A;  3AI9 X;  4YPY A;  4YQC A;  4MCC A;  4YQS A;  4YQT A;  3KW2 A;  3KNU A;  1O6D A;  4YQJ A;  4JWF A;  4YQ1 A;  3ONP A;  4PZK A;  4YQ8 A;  4YQA A;  3GYQ A;  4JWJ A;  4CNE A;  4YQG A;  4YQ5 A;  1MXI A;  3E5Y A;  4CNG A;  3OIN A;  1VHK A;  4YPZ A;  1ZJR A;  3N4J A;  2V3K A;  5GMC A;  3IEF A;  4KDZ A;  1GZ0 A;  4E8B A;  4YQK A;  3DCM X;  3AIA A;  4YQQ A;  5D9F A;  4YQD A;  2QWV A;  4YVJ A;  1J85 A;  3QUV A;  4YQ2 A;  3L8U A;  1V2X A;  4YQ4 A;  3KTY A;  4JWH A;  4YVI A;  1P9P A;  4YVG A;  3BBD A;  3OIJ A;  1UAM A;  4YVH A;  4YQ6 A;  2YY8 A;  4YQ0 A;  3OII A;  2Z0Y A;  4XBO A;  1X7P A;  4MCB A;  4YVK A;  1V6Z A;  3BBH A;  4KGN A;  3NK6 A;  2EGW A;  4YPX A;  4YQ9 A;  4CNF A;  4X3L A;  2CX8 A;  1Z85 A;  2O3A A;  1UAJ A;  5GM8 A;  4FAK A;  1NS5 A;  5GMB A;  4YQB A;  4J3C A;  4H3Y A;  4YQP A;  5CO4 A;  4YQ7 A;  2I6D A;  4H3Z A;  1OY5 A;  2V3J A;  3AXZ A;  4RG1 A;  1NXZ A;  4L69 A;  4YQN A;  3O7B A;  4YQO A;  4IG6 A;  4YQI A;  2HA8 A;  4YQL A;  1IPA A;  1VHY A;  3KY7 A;  4JWG A;  3N4K A;  4X3M A;  4YQ3 A;  3ILK A;  2QMM A;  1K3R A;  4YQR A;  1X7O A;  4JAL A;  4JAK A;  1TO0 A;  4MCD A;  4FMW A;  3NK7 A;  1UAL A;  2EGV A;  1UAK A;  4CND A;  5FAI A;  4YPW A;  3BBE A;  3IC6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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