4YVIA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
Knots found
sequence length
247
structure length
239
Chain Sequence
HMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 65
structure length 239
sequence length 247
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yviA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yviA01
4YQ1A 2V3KA 4KDZA 1V2XA 3IC6A 4CNGA 2YY8A 3E5YA 1UAKA 3BBHA 4YQJA 2QWVA 4YQ0A 3BBEA 1NS5A 4FAKA 4YQ8A 4JALA 3GYQA 3KNUA 4YQ5A 1K3RA 5GMBA 4YQNA 4YPXA 5GM8A 2CX8A 2EGWA 1ZJRA 4CNFA 3AI9X 1OY5A 4YQ2A 4YQPA 4YQ7A 3IEFA 4MCCA 4YQ4A 4YVHA 2EGVA 5FAIA 4YQ6A 4X3MA 4L69A 2HA8A 4YVGA 4YQSA 4YQTA 3NK7A 4YQKA 3L8UA 4E8BA 4MCBA 5CO4A 4H3ZA 1IPAA 4YVKA 4YPYA 2O3AA 3O7BA 1VHYA 4XBOA 4JAKA 1O6DA 3OIJA 3KTYA 5GMCA 1VHKA 3BBDA 3N4JA 4YQQA 4IG6A 3ONPA 3KW2A 4YPZA 3ILKA 4YQOA 3OINA 1MXIA 1TO0A 4RG1A 4X3LA 4CNEA 4J3CA 1Z85A 4KGNA 1P9PA 2Z0YA 4YQLA 4YQAA 1J85A 3QUVA 3NK6A 4YQ3A 4YPWA 1VH0A 3OIIA 2V3JA 3N4KA 4PZKA 4YVIA 1UAMA 1X7OA 2I6DA 1X7PA 4YVJA 4MCDA 3KY7A 1NXZA 4CNDA 4YQ9A 4YQBA 5D9FA 4YQGA 4H3YA 1GZ0A 2QMMA 3AXZA 4YQDA 4YQCA 4YQIA 1UALA 3DCMX 4YQRA 1V6ZA 3AIAA 1UAJA
chains in the Genus database with same CATH superfamily
4YQ1A 2V3KA 4JWJA 1V2XA 3IC6A 4KDZA 4CNGA 2YY8A 3E5YA 1UAKA 3BBHA 4YQJA 1CO0A 1WRPR 2QWVA 1ZT9A 4YQ0A 3BBEA 4FMWA 1NS5A 4FAKA 4YQ8A 4JALA 3GYQA 3KNUA 4YQ5A 1K3RA 5GMBA 1WRTR 4YQNA 4YPXA 5GM8A 2CX8A 2EGWA 1ZJRA 4CNFA 3AI9X 1OY5A 4YQ2A 4YQPA 4YQ7A 4MCCA 3IEFA 4YQ4A 4YVHA 1TRRA 1WRSR 2EGVA 5FAIA 4JWHA 4YQ6A 4X3MA 3WRPA 4JWFA 4L69A 3G1CA 1UAJA 2HA8A 4YVGA 4YQSA 4YQTA 3NK7A 4YQKA 3L8UA 3FRWA 4E8BA 4MCBA 3KORA 5CO4A 4H3ZA 1IPAA 4YVKA 4YPYA 2O3AA 3O7BA 2OZ9R 1VHYA 4XBOA 4JAKA 3SSXN 1O6DA 2XDIA 3OIJA 3KTYA 5GMCA 1VHKA 3BBDA 3N4JA 4YQQA 4IG6A 3ONPA 3KW2A 4YPZA 3ILKA 4YQOA 3OINA 1MXIA 1TO0A 4RG1A 4X3LA 4CNEA 4J3CA 1Z85A 4KGNA 1P9PA 2Z0YA 4YQLA 4YQAA 1J85A 1MI7R 3QUVA 3NK6A 4YQ3A 4YPWA 1VH0A 3OIIA 2V3JA 3N4KA 4PZKA 4YVIA 1UAMA 1X7OA 2I6DA 4JWGA 1X7PA 4YVJA 4MCDA 1TROA 3KY7A 1NXZA 4CNDA 4YQ9A 4YQBA 5D9FA 4YQGA 4H3YA 1GZ0A 2QMMA 3AXZA 4YQDA 4YQCA 4YQIA 1JHGA 3SSWN 1UALA 3DCMX 4YQRA 1V6ZA 3AIAA 1RCSA
chains in the Genus database with same CATH topology
4YQ1A 2V3KA 4JWJA 1V2XA 3IC6A 4KDZA 4CNGA 2YY8A 3E5YA 1UAKA 3BBHA 4YQJA 2QWVA 4YQ0A 3BBEA 4FMWA 1NS5A 4FAKA 4YQ8A 4JALA 3GYQA 3KNUA 4YQ5A 1K3RA 5GMBA 4YQNA 4YPXA 5GM8A 2CX8A 2EGWA 1ZJRA 4CNFA 3AI9X 1OY5A 4YQ2A 4YQPA 4YQ7A 3IEFA 4MCCA 4YQ4A 4YVHA 2EGVA 5FAIA 4JWHA 4YQ6A 4X3MA 4JWFA 4L69A 2HA8A 4YVGA 4YQSA 4YQTA 3NK7A 4YQKA 3L8UA 4E8BA 4MCBA 5CO4A 4H3ZA 1IPAA 4YVKA 4YPYA 2O3AA 3O7BA 1VHYA 4XBOA 4JAKA 1O6DA 3OIJA 3KTYA 5GMCA 1VHKA 3BBDA 3N4JA 4YQQA 4IG6A 3ONPA 3KW2A 4YPZA 3ILKA 4YQOA 3OINA 1MXIA 1TO0A 4RG1A 4X3LA 4CNEA 4J3CA 1Z85A 4KGNA 1P9PA 2Z0YA 4YQLA 4YQAA 1J85A 3QUVA 3NK6A 4YQ3A 4YPWA 1VH0A 3OIIA 2V3JA 3N4KA 4PZKA 4YVIA 1UAMA 1X7OA 2I6DA 4JWGA 1X7PA 4YVJA 4MCDA 3KY7A 1NXZA 4CNDA 4YQ9A 4YQBA 5D9FA 4YQGA 4H3YA 1GZ0A 2QMMA 3AXZA 4YQDA 4YQCA 4YQIA 1UALA 3DCMX 4YQRA 1V6ZA 3AIAA 1UAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ1 A;  2V3K A;  4KDZ A;  1V2X A;  3IC6 A;  4CNG A;  2YY8 A;  3E5Y A;  1UAK A;  3BBH A;  4YQJ A;  2QWV A;  4YQ0 A;  3BBE A;  1NS5 A;  4FAK A;  4YQ8 A;  4JAL A;  3GYQ A;  3KNU A;  4YQ5 A;  1K3R A;  5GMB A;  4YQN A;  4YPX A;  5GM8 A;  2CX8 A;  2EGW A;  1ZJR A;  4CNF A;  3AI9 X;  1OY5 A;  4YQ2 A;  4YQP A;  4YQ7 A;  3IEF A;  4MCC A;  4YQ4 A;  4YVH A;  2EGV A;  5FAI A;  4YQ6 A;  4X3M A;  4L69 A;  2HA8 A;  4YVG A;  4YQS A;  4YQT A;  3NK7 A;  4YQK A;  3L8U A;  4E8B A;  4MCB A;  5CO4 A;  4H3Z A;  1IPA A;  4YVK A;  4YPY A;  2O3A A;  3O7B A;  1VHY A;  4XBO A;  4JAK A;  1O6D A;  3OIJ A;  3KTY A;  5GMC A;  1VHK A;  3BBD A;  3N4J A;  4YQQ A;  4IG6 A;  3ONP A;  3KW2 A;  4YPZ A;  3ILK A;  4YQO A;  3OIN A;  1MXI A;  1TO0 A;  4RG1 A;  4X3L A;  4CNE A;  4J3C A;  1Z85 A;  4KGN A;  1P9P A;  2Z0Y A;  4YQL A;  4YQA A;  1J85 A;  3QUV A;  3NK6 A;  4YQ3 A;  4YPW A;  1VH0 A;  3OII A;  2V3J A;  3N4K A;  4PZK A;  4YVI A;  1UAM A;  1X7O A;  2I6D A;  1X7P A;  4YVJ A;  4MCD A;  3KY7 A;  1NXZ A;  4CND A;  4YQ9 A;  4YQB A;  5D9F A;  4YQG A;  4H3Y A;  1GZ0 A;  2QMM A;  3AXZ A;  4YQD A;  4YQC A;  4YQI A;  1UAL A;  3DCM X;  4YQR A;  1V6Z A;  3AIA A;  1UAJ A; 
#chains in the Genus database with same CATH topology
 4YQ1 A;  2V3K A;  4JWJ A;  1V2X A;  3IC6 A;  4KDZ A;  4CNG A;  2YY8 A;  3E5Y A;  1UAK A;  3BBH A;  4YQJ A;  1CO0 A;  1WRP R;  2QWV A;  1ZT9 A;  4YQ0 A;  3BBE A;  4FMW A;  1NS5 A;  4FAK A;  4YQ8 A;  4JAL A;  3GYQ A;  3KNU A;  4YQ5 A;  1K3R A;  5GMB A;  1WRT R;  4YQN A;  4YPX A;  5GM8 A;  2CX8 A;  2EGW A;  1ZJR A;  4CNF A;  3AI9 X;  1OY5 A;  4YQ2 A;  4YQP A;  4YQ7 A;  4MCC A;  3IEF A;  4YQ4 A;  4YVH A;  1TRR A;  1WRS R;  2EGV A;  5FAI A;  4JWH A;  4YQ6 A;  4X3M A;  3WRP A;  4JWF A;  4L69 A;  3G1C A;  1UAJ A;  2HA8 A;  4YVG A;  4YQS A;  4YQT A;  3NK7 A;  4YQK A;  3L8U A;  3FRW A;  4E8B A;  4MCB A;  3KOR A;  5CO4 A;  4H3Z A;  1IPA A;  4YVK A;  4YPY A;  2O3A A;  3O7B A;  2OZ9 R;  1VHY A;  4XBO A;  4JAK A;  3SSX N;  1O6D A;  2XDI A;  3OIJ A;  3KTY A;  5GMC A;  1VHK A;  3BBD A;  3N4J A;  4YQQ A;  4IG6 A;  3ONP A;  3KW2 A;  4YPZ A;  3ILK A;  4YQO A;  3OIN A;  1MXI A;  1TO0 A;  4RG1 A;  4X3L A;  4CNE A;  4J3C A;  1Z85 A;  4KGN A;  1P9P A;  2Z0Y A;  4YQL A;  4YQA A;  1J85 A;  1MI7 R;  3QUV A;  3NK6 A;  4YQ3 A;  4YPW A;  1VH0 A;  3OII A;  2V3J A;  3N4K A;  4PZK A;  4YVI A;  1UAM A;  1X7O A;  2I6D A;  4JWG A;  1X7P A;  4YVJ A;  4MCD A;  1TRO A;  3KY7 A;  1NXZ A;  4CND A;  4YQ9 A;  4YQB A;  5D9F A;  4YQG A;  4H3Y A;  1GZ0 A;  2QMM A;  3AXZ A;  4YQD A;  4YQC A;  4YQI A;  1JHG A;  3SSW N;  1UAL A;  3DCM X;  4YQR A;  1V6Z A;  3AIA A;  1RCS A; 
#chains in the Genus database with same CATH homology
 4YQ1 A;  2V3K A;  4JWJ A;  1V2X A;  3IC6 A;  4KDZ A;  4CNG A;  2YY8 A;  3E5Y A;  1UAK A;  3BBH A;  4YQJ A;  2QWV A;  4YQ0 A;  3BBE A;  4FMW A;  1NS5 A;  4FAK A;  4YQ8 A;  4JAL A;  3GYQ A;  3KNU A;  4YQ5 A;  1K3R A;  5GMB A;  4YQN A;  4YPX A;  5GM8 A;  2CX8 A;  2EGW A;  1ZJR A;  4CNF A;  3AI9 X;  1OY5 A;  4YQ2 A;  4YQP A;  4YQ7 A;  3IEF A;  4MCC A;  4YQ4 A;  4YVH A;  2EGV A;  5FAI A;  4JWH A;  4YQ6 A;  4X3M A;  4JWF A;  4L69 A;  2HA8 A;  4YVG A;  4YQS A;  4YQT A;  3NK7 A;  4YQK A;  3L8U A;  4E8B A;  4MCB A;  5CO4 A;  4H3Z A;  1IPA A;  4YVK A;  4YPY A;  2O3A A;  3O7B A;  1VHY A;  4XBO A;  4JAK A;  1O6D A;  3OIJ A;  3KTY A;  5GMC A;  1VHK A;  3BBD A;  3N4J A;  4YQQ A;  4IG6 A;  3ONP A;  3KW2 A;  4YPZ A;  3ILK A;  4YQO A;  3OIN A;  1MXI A;  1TO0 A;  4RG1 A;  4X3L A;  4CNE A;  4J3C A;  1Z85 A;  4KGN A;  1P9P A;  2Z0Y A;  4YQL A;  4YQA A;  1J85 A;  3QUV A;  3NK6 A;  4YQ3 A;  4YPW A;  1VH0 A;  3OII A;  2V3J A;  3N4K A;  4PZK A;  4YVI A;  1UAM A;  1X7O A;  2I6D A;  4JWG A;  1X7P A;  4YVJ A;  4MCD A;  3KY7 A;  1NXZ A;  4CND A;  4YQ9 A;  4YQB A;  5D9F A;  4YQG A;  4H3Y A;  1GZ0 A;  2QMM A;  3AXZ A;  4YQD A;  4YQC A;  4YQI A;  1UAL A;  3DCM X;  4YQR A;  1V6Z A;  3AIA A;  1UAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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