4YVJA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna variant (g36u)
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 68
structure length 239
sequence length 248
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvjA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvjA01
3QUVA 4YQTA 4CNFA 2V3JA 4CNEA 5GMCA 3IC6A 2EGVA 3NK7A 2V3KA 1UAKA 1UAMA 3ONPA 4YQLA 4YQ9A 2HA8A 4XBOA 5FAIA 4YQNA 4YQKA 4E8BA 1P9PA 4L69A 4YQ7A 4RG1A 1UALA 3L8UA 3OINA 4KDZA 1VHYA 3ILKA 3DCMX 4J3CA 4JALA 1GZ0A 4YPYA 4YQOA 1K3RA 4MCCA 3AI9X 4JAKA 4YPXA 1NS5A 4YQ4A 4CNDA 5CO4A 1X7OA 4YQ2A 3BBHA 3BBDA 4YQJA 1VHKA 4X3MA 3KTYA 3KNUA 4YQ0A 1V6ZA 3E5YA 1IPAA 4YPWA 4IG6A 3N4JA 4YQ8A 3AXZA 3AIAA 4MCDA 4YVGA 1UAJA 2O3AA 5GMBA 1MXIA 1NXZA 2CX8A 5D9FA 3N4KA 3KW2A 4YQ1A 1Z85A 4YQGA 4YVJA 4YQCA 4YQ3A 5GM8A 4YQ6A 4YQBA 4YQDA 3NK6A 4YQAA 4YQIA 4KGNA 4CNGA 1X7PA 4YVIA 3OIJA 3IEFA 4X3LA 3KY7A 4YVKA 1ZJRA 4YQ5A 2I6DA 1O6DA 4YQPA 4YQQA 4H3ZA 4H3YA 3O7BA 3OIIA 4YVHA 4YPZA 4YQRA 4YQSA 1J85A 1TO0A 4MCBA 3GYQA 3BBEA 1OY5A 1VH0A 1V2XA 2YY8A 2QWVA 4PZKA 2Z0YA 2QMMA 4FAKA 2EGWA
chains in the Genus database with same CATH superfamily
3QUVA 4YQTA 4CNFA 2V3JA 4CNEA 5GMCA 3IC6A 1WRSR 2EGVA 3NK7A 2V3KA 1UAKA 1UAMA 3ONPA 4YQLA 4YQ9A 2HA8A 4XBOA 5FAIA 1WRTR 4YQNA 4YQKA 3KORA 4E8BA 1P9PA 4L69A 4YQ7A 4RG1A 1UALA 3L8UA 3OINA 1RCSA 1CO0A 1VHYA 4KDZA 3ILKA 3DCMX 4J3CA 4JALA 1GZ0A 4JWGA 4YPYA 4YQOA 1K3RA 4MCCA 3AI9X 4JAKA 4YPXA 1NS5A 4YQ4A 4CNDA 5CO4A 4JWFA 1X7OA 1MI7R 4YQ2A 3BBHA 3BBDA 1JHGA 4YQJA 1VHKA 4X3MA 3KTYA 3KNUA 4YQ0A 1V6ZA 3E5YA 1IPAA 4YPWA 4IG6A 3N4JA 2OZ9R 3SSWN 1TROA 4YQ8A 3AXZA 3AIAA 4MCDA 4YVGA 1ZT9A 1UAJA 2O3AA 5GMBA 1MXIA 1NXZA 5D9FA 2CX8A 3FRWA 3N4KA 3KW2A 4JWJA 4YQ1A 1Z85A 4YQGA 4YVJA 4YQCA 1TRRA 4YQ3A 4JWHA 5GM8A 4YQ6A 4YQBA 3SSXN 4YQDA 3NK6A 4YQAA 3WRPA 4YQIA 4KGNA 4CNGA 1X7PA 4YVIA 3OIJA 3IEFA 4X3LA 3KY7A 4YVKA 1ZJRA 4YQ5A 2I6DA 1O6DA 3G1CA 4YQPA 4YQQA 4H3ZA 4FMWA 4H3YA 3O7BA 3OIIA 1WRPR 4YVHA 4YPZA 4YQRA 4YQSA 1J85A 1TO0A 4MCBA 3GYQA 3BBEA 1OY5A 1VH0A 1V2XA 2XDIA 2YY8A 2QWVA 4PZKA 2Z0YA 2QMMA 4FAKA 2EGWA
chains in the Genus database with same CATH topology
3QUVA 4YQTA 4CNFA 2V3JA 4CNEA 5GMCA 3IC6A 2EGVA 3NK7A 2V3KA 1UAKA 1UAMA 3ONPA 4YQLA 4YQ9A 2HA8A 4XBOA 5FAIA 4YQNA 4YQKA 4E8BA 1P9PA 4L69A 4YQ7A 4RG1A 1UALA 3L8UA 3OINA 4KDZA 1VHYA 3ILKA 3DCMX 4J3CA 4JALA 1GZ0A 4JWGA 4YPYA 4YQOA 1K3RA 4MCCA 3AI9X 4JAKA 4YPXA 1NS5A 4YQ4A 4CNDA 5CO4A 4JWFA 1X7OA 4YQ2A 3BBHA 3BBDA 4YQJA 1VHKA 4X3MA 3KTYA 3KNUA 4YQ0A 1V6ZA 3E5YA 1IPAA 4YPWA 4IG6A 3N4JA 4YQ8A 3AXZA 3AIAA 4MCDA 4YVGA 1UAJA 2O3AA 5GMBA 1MXIA 1NXZA 2CX8A 5D9FA 3N4KA 3KW2A 4JWJA 4YQ1A 1Z85A 4YQGA 4YVJA 4YQCA 4YQ3A 4JWHA 5GM8A 4YQ6A 4YQBA 4YQDA 3NK6A 4YQAA 4YQIA 4KGNA 4CNGA 1X7PA 4YVIA 3OIJA 3IEFA 4X3LA 3KY7A 4YVKA 1ZJRA 4YQ5A 2I6DA 1O6DA 4YQPA 4YQQA 4H3ZA 4FMWA 4H3YA 3O7BA 3OIIA 4YVHA 4YPZA 4YQRA 4YQSA 1J85A 1TO0A 4MCBA 3GYQA 3BBEA 1OY5A 1VH0A 1V2XA 2YY8A 2QWVA 4PZKA 2Z0YA 2QMMA 4FAKA 2EGWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QUV A;  4YQT A;  4CNF A;  2V3J A;  4CNE A;  5GMC A;  3IC6 A;  2EGV A;  3NK7 A;  2V3K A;  1UAK A;  1UAM A;  3ONP A;  4YQL A;  4YQ9 A;  2HA8 A;  4XBO A;  5FAI A;  4YQN A;  4YQK A;  4E8B A;  1P9P A;  4L69 A;  4YQ7 A;  4RG1 A;  1UAL A;  3L8U A;  3OIN A;  4KDZ A;  1VHY A;  3ILK A;  3DCM X;  4J3C A;  4JAL A;  1GZ0 A;  4YPY A;  4YQO A;  1K3R A;  4MCC A;  3AI9 X;  4JAK A;  4YPX A;  1NS5 A;  4YQ4 A;  4CND A;  5CO4 A;  1X7O A;  4YQ2 A;  3BBH A;  3BBD A;  4YQJ A;  1VHK A;  4X3M A;  3KTY A;  3KNU A;  4YQ0 A;  1V6Z A;  3E5Y A;  1IPA A;  4YPW A;  4IG6 A;  3N4J A;  4YQ8 A;  3AXZ A;  3AIA A;  4MCD A;  4YVG A;  1UAJ A;  2O3A A;  5GMB A;  1MXI A;  1NXZ A;  2CX8 A;  5D9F A;  3N4K A;  3KW2 A;  4YQ1 A;  1Z85 A;  4YQG A;  4YVJ A;  4YQC A;  4YQ3 A;  5GM8 A;  4YQ6 A;  4YQB A;  4YQD A;  3NK6 A;  4YQA A;  4YQI A;  4KGN A;  4CNG A;  1X7P A;  4YVI A;  3OIJ A;  3IEF A;  4X3L A;  3KY7 A;  4YVK A;  1ZJR A;  4YQ5 A;  2I6D A;  1O6D A;  4YQP A;  4YQQ A;  4H3Z A;  4H3Y A;  3O7B A;  3OII A;  4YVH A;  4YPZ A;  4YQR A;  4YQS A;  1J85 A;  1TO0 A;  4MCB A;  3GYQ A;  3BBE A;  1OY5 A;  1VH0 A;  1V2X A;  2YY8 A;  2QWV A;  4PZK A;  2Z0Y A;  2QMM A;  4FAK A;  2EGW A; 
#chains in the Genus database with same CATH topology
 3QUV A;  4YQT A;  4CNF A;  2V3J A;  4CNE A;  5GMC A;  3IC6 A;  1WRS R;  2EGV A;  3NK7 A;  2V3K A;  1UAK A;  1UAM A;  3ONP A;  4YQL A;  4YQ9 A;  2HA8 A;  4XBO A;  5FAI A;  1WRT R;  4YQN A;  4YQK A;  3KOR A;  4E8B A;  1P9P A;  4L69 A;  4YQ7 A;  4RG1 A;  1UAL A;  3L8U A;  3OIN A;  1RCS A;  1CO0 A;  1VHY A;  4KDZ A;  3ILK A;  3DCM X;  4J3C A;  4JAL A;  1GZ0 A;  4JWG A;  4YPY A;  4YQO A;  1K3R A;  4MCC A;  3AI9 X;  4JAK A;  4YPX A;  1NS5 A;  4YQ4 A;  4CND A;  5CO4 A;  4JWF A;  1X7O A;  1MI7 R;  4YQ2 A;  3BBH A;  3BBD A;  1JHG A;  4YQJ A;  1VHK A;  4X3M A;  3KTY A;  3KNU A;  4YQ0 A;  1V6Z A;  3E5Y A;  1IPA A;  4YPW A;  4IG6 A;  3N4J A;  2OZ9 R;  3SSW N;  1TRO A;  4YQ8 A;  3AXZ A;  3AIA A;  4MCD A;  4YVG A;  1ZT9 A;  1UAJ A;  2O3A A;  5GMB A;  1MXI A;  1NXZ A;  5D9F A;  2CX8 A;  3FRW A;  3N4K A;  3KW2 A;  4JWJ A;  4YQ1 A;  1Z85 A;  4YQG A;  4YVJ A;  4YQC A;  1TRR A;  4YQ3 A;  4JWH A;  5GM8 A;  4YQ6 A;  4YQB A;  3SSX N;  4YQD A;  3NK6 A;  4YQA A;  3WRP A;  4YQI A;  4KGN A;  4CNG A;  1X7P A;  4YVI A;  3OIJ A;  3IEF A;  4X3L A;  3KY7 A;  4YVK A;  1ZJR A;  4YQ5 A;  2I6D A;  1O6D A;  3G1C A;  4YQP A;  4YQQ A;  4H3Z A;  4FMW A;  4H3Y A;  3O7B A;  3OII A;  1WRP R;  4YVH A;  4YPZ A;  4YQR A;  4YQS A;  1J85 A;  1TO0 A;  4MCB A;  3GYQ A;  3BBE A;  1OY5 A;  1VH0 A;  1V2X A;  2XDI A;  2YY8 A;  2QWV A;  4PZK A;  2Z0Y A;  2QMM A;  4FAK A;  2EGW A; 
#chains in the Genus database with same CATH homology
 3QUV A;  4YQT A;  4CNF A;  2V3J A;  4CNE A;  5GMC A;  3IC6 A;  2EGV A;  3NK7 A;  2V3K A;  1UAK A;  1UAM A;  3ONP A;  4YQL A;  4YQ9 A;  2HA8 A;  4XBO A;  5FAI A;  4YQN A;  4YQK A;  4E8B A;  1P9P A;  4L69 A;  4YQ7 A;  4RG1 A;  1UAL A;  3L8U A;  3OIN A;  4KDZ A;  1VHY A;  3ILK A;  3DCM X;  4J3C A;  4JAL A;  1GZ0 A;  4JWG A;  4YPY A;  4YQO A;  1K3R A;  4MCC A;  3AI9 X;  4JAK A;  4YPX A;  1NS5 A;  4YQ4 A;  4CND A;  5CO4 A;  4JWF A;  1X7O A;  4YQ2 A;  3BBH A;  3BBD A;  4YQJ A;  1VHK A;  4X3M A;  3KTY A;  3KNU A;  4YQ0 A;  1V6Z A;  3E5Y A;  1IPA A;  4YPW A;  4IG6 A;  3N4J A;  4YQ8 A;  3AXZ A;  3AIA A;  4MCD A;  4YVG A;  1UAJ A;  2O3A A;  5GMB A;  1MXI A;  1NXZ A;  2CX8 A;  5D9F A;  3N4K A;  3KW2 A;  4JWJ A;  4YQ1 A;  1Z85 A;  4YQG A;  4YVJ A;  4YQC A;  4YQ3 A;  4JWH A;  5GM8 A;  4YQ6 A;  4YQB A;  4YQD A;  3NK6 A;  4YQA A;  4YQI A;  4KGN A;  4CNG A;  1X7P A;  4YVI A;  3OIJ A;  3IEF A;  4X3L A;  3KY7 A;  4YVK A;  1ZJR A;  4YQ5 A;  2I6D A;  1O6D A;  4YQP A;  4YQQ A;  4H3Z A;  4FMW A;  4H3Y A;  3O7B A;  3OII A;  4YVH A;  4YPZ A;  4YQR A;  4YQS A;  1J85 A;  1TO0 A;  4MCB A;  3GYQ A;  3BBE A;  1OY5 A;  1VH0 A;  1V2X A;  2YY8 A;  2QWV A;  4PZK A;  2Z0Y A;  2QMM A;  4FAK A;  2EGW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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