4YVKA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna variant (g36c)
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 68
structure length 239
sequence length 248
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvkA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvkA01
1UALA 4YQGA 2EGVA 3E5YA 3ILKA 4YQSA 4YPYA 4YQ2A 3L8UA 5FAIA 2CX8A 4YPXA 4KDZA 4E8BA 3DCMX 1V2XA 3QUVA 1VH0A 3IC6A 1TO0A 4L69A 4JAKA 4YQ9A 4YQ0A 4YPZA 4YQOA 4YQIA 4YQ8A 4H3YA 4YVGA 3BBDA 4JALA 5D9FA 2V3JA 3GYQA 1O6DA 4H3ZA 3O7BA 4CNFA 4YQ4A 1MXIA 3OINA 4FAKA 1VHYA 1ZJRA 2QWVA 2YY8A 3OIIA 4MCBA 4CNEA 4IG6A 1X7OA 1NS5A 4YQCA 3BBHA 4X3LA 4XBOA 3AIAA 3KY7A 4YVHA 3AI9X 4RG1A 4YQ1A 3IEFA 1GZ0A 5CO4A 4CNDA 4YQKA 1Z85A 4YQTA 3KNUA 1OY5A 4CNGA 1UAMA 4YQQA 3NK6A 4KGNA 5GMBA 1J85A 4YPWA 3ONPA 4YQBA 4J3CA 4X3MA 4YQJA 4YVIA 4YQAA 4YQPA 2V3KA 3OIJA 1UAKA 3BBEA 3N4KA 3N4JA 4YVJA 2EGWA 2Z0YA 4YQ5A 2HA8A 4YQ7A 1K3RA 5GM8A 4YQNA 1UAJA 4YQLA 3KTYA 4YQ6A 5GMCA 1NXZA 1P9PA 2QMMA 4YQRA 2O3AA 2I6DA 4YQDA 1X7PA 4YQ3A 4YVKA 4MCDA 1VHKA 3KW2A 3AXZA 4PZKA 3NK7A 1V6ZA 1IPAA 4MCCA
chains in the Genus database with same CATH superfamily
1UALA 4YQGA 2EGVA 3E5YA 3ILKA 4YQSA 4YPYA 4YQ2A 3L8UA 5FAIA 2CX8A 4YPXA 4KDZA 4E8BA 3DCMX 1V2XA 3QUVA 1ZT9A 1VH0A 4JWHA 1WRPR 3IC6A 1TO0A 4L69A 4JAKA 4YQ9A 4YQ0A 4YPZA 4YQOA 1TROA 4YQIA 4YQ8A 4H3YA 4YVGA 3BBDA 1JHGA 4JALA 1TRRA 1CO0A 5D9FA 3FRWA 4JWJA 2V3JA 3GYQA 1O6DA 4FMWA 3SSXN 4H3ZA 3O7BA 4CNFA 4YQ4A 1MXIA 3OINA 4FAKA 1VHYA 3KORA 1ZJRA 2QWVA 2YY8A 3OIIA 4MCBA 4CNEA 4IG6A 1X7OA 1NS5A 4YQCA 3BBHA 4X3LA 4XBOA 3AIAA 3KY7A 4YVHA 3AI9X 4RG1A 4YQ1A 3IEFA 1WRSR 1GZ0A 5CO4A 4CNDA 4YQKA 1Z85A 1RCSA 4YQTA 4JWGA 3KNUA 1OY5A 4CNGA 1UAMA 4YQQA 3WRPA 3NK6A 4KGNA 5GMBA 1J85A 4YPWA 3ONPA 4YQBA 4J3CA 2OZ9R 4X3MA 3SSWN 1MI7R 4YQJA 4YVIA 4YQAA 4YQPA 2V3KA 3OIJA 1UAKA 3BBEA 3N4KA 3N4JA 4YVJA 2EGWA 2Z0YA 4YQ5A 2HA8A 4YQ7A 1K3RA 5GM8A 4YQNA 1UAJA 4YQLA 3KTYA 1WRTR 4YQ6A 5GMCA 1NXZA 1P9PA 2QMMA 2XDIA 4YQRA 2O3AA 2I6DA 4JWFA 4YQDA 1X7PA 4YQ3A 4YVKA 4MCDA 1VHKA 3KW2A 3AXZA 3G1CA 4PZKA 3NK7A 1V6ZA 1IPAA 4MCCA
chains in the Genus database with same CATH topology
1UALA 4YQGA 2EGVA 3E5YA 3ILKA 4YQSA 4YPYA 4YQ2A 3L8UA 5FAIA 2CX8A 4YPXA 4KDZA 4E8BA 3DCMX 1V2XA 3QUVA 1VH0A 4JWHA 3IC6A 1TO0A 4L69A 4JAKA 4YQ9A 4YQ0A 4YPZA 4YQOA 4YQIA 4YQ8A 4H3YA 4YVGA 3BBDA 4JALA 5D9FA 4JWJA 2V3JA 3GYQA 1O6DA 4FMWA 4H3ZA 3O7BA 4CNFA 4YQ4A 1MXIA 3OINA 4FAKA 1VHYA 1ZJRA 2QWVA 2YY8A 3OIIA 4MCBA 4CNEA 4IG6A 1X7OA 1NS5A 4YQCA 3BBHA 4X3LA 4XBOA 3AIAA 3KY7A 4YVHA 3AI9X 4RG1A 4YQ1A 3IEFA 1GZ0A 5CO4A 4CNDA 4YQKA 1Z85A 4YQTA 4JWGA 3KNUA 1OY5A 4CNGA 1UAMA 4YQQA 3NK6A 4KGNA 5GMBA 1J85A 4YPWA 3ONPA 4YQBA 4J3CA 4X3MA 4YQJA 4YVIA 4YQAA 4YQPA 2V3KA 3OIJA 1UAKA 3BBEA 3N4KA 3N4JA 4YVJA 2EGWA 2Z0YA 4YQ5A 2HA8A 4YQ7A 1K3RA 5GM8A 4YQNA 1UAJA 4YQLA 3KTYA 4YQ6A 5GMCA 1NXZA 1P9PA 2QMMA 4YQRA 2O3AA 2I6DA 4JWFA 4YQDA 1X7PA 4YQ3A 4YVKA 4MCDA 1VHKA 3KW2A 3AXZA 4PZKA 3NK7A 1V6ZA 1IPAA 4MCCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UAL A;  4YQG A;  2EGV A;  3E5Y A;  3ILK A;  4YQS A;  4YPY A;  4YQ2 A;  3L8U A;  5FAI A;  2CX8 A;  4YPX A;  4KDZ A;  4E8B A;  3DCM X;  1V2X A;  3QUV A;  1VH0 A;  3IC6 A;  1TO0 A;  4L69 A;  4JAK A;  4YQ9 A;  4YQ0 A;  4YPZ A;  4YQO A;  4YQI A;  4YQ8 A;  4H3Y A;  4YVG A;  3BBD A;  4JAL A;  5D9F A;  2V3J A;  3GYQ A;  1O6D A;  4H3Z A;  3O7B A;  4CNF A;  4YQ4 A;  1MXI A;  3OIN A;  4FAK A;  1VHY A;  1ZJR A;  2QWV A;  2YY8 A;  3OII A;  4MCB A;  4CNE A;  4IG6 A;  1X7O A;  1NS5 A;  4YQC A;  3BBH A;  4X3L A;  4XBO A;  3AIA A;  3KY7 A;  4YVH A;  3AI9 X;  4RG1 A;  4YQ1 A;  3IEF A;  1GZ0 A;  5CO4 A;  4CND A;  4YQK A;  1Z85 A;  4YQT A;  3KNU A;  1OY5 A;  4CNG A;  1UAM A;  4YQQ A;  3NK6 A;  4KGN A;  5GMB A;  1J85 A;  4YPW A;  3ONP A;  4YQB A;  4J3C A;  4X3M A;  4YQJ A;  4YVI A;  4YQA A;  4YQP A;  2V3K A;  3OIJ A;  1UAK A;  3BBE A;  3N4K A;  3N4J A;  4YVJ A;  2EGW A;  2Z0Y A;  4YQ5 A;  2HA8 A;  4YQ7 A;  1K3R A;  5GM8 A;  4YQN A;  1UAJ A;  4YQL A;  3KTY A;  4YQ6 A;  5GMC A;  1NXZ A;  1P9P A;  2QMM A;  4YQR A;  2O3A A;  2I6D A;  4YQD A;  1X7P A;  4YQ3 A;  4YVK A;  4MCD A;  1VHK A;  3KW2 A;  3AXZ A;  4PZK A;  3NK7 A;  1V6Z A;  1IPA A;  4MCC A; 
#chains in the Genus database with same CATH topology
 1UAL A;  4YQG A;  2EGV A;  3E5Y A;  3ILK A;  4YQS A;  4YPY A;  4YQ2 A;  3L8U A;  5FAI A;  2CX8 A;  4YPX A;  4KDZ A;  4E8B A;  3DCM X;  1V2X A;  3QUV A;  1ZT9 A;  1VH0 A;  4JWH A;  1WRP R;  3IC6 A;  1TO0 A;  4L69 A;  4JAK A;  4YQ9 A;  4YQ0 A;  4YPZ A;  4YQO A;  1TRO A;  4YQI A;  4YQ8 A;  4H3Y A;  4YVG A;  3BBD A;  1JHG A;  4JAL A;  1TRR A;  1CO0 A;  5D9F A;  3FRW A;  4JWJ A;  2V3J A;  3GYQ A;  1O6D A;  4FMW A;  3SSX N;  4H3Z A;  3O7B A;  4CNF A;  4YQ4 A;  1MXI A;  3OIN A;  4FAK A;  1VHY A;  3KOR A;  1ZJR A;  2QWV A;  2YY8 A;  3OII A;  4MCB A;  4CNE A;  4IG6 A;  1X7O A;  1NS5 A;  4YQC A;  3BBH A;  4X3L A;  4XBO A;  3AIA A;  3KY7 A;  4YVH A;  3AI9 X;  4RG1 A;  4YQ1 A;  3IEF A;  1WRS R;  1GZ0 A;  5CO4 A;  4CND A;  4YQK A;  1Z85 A;  1RCS A;  4YQT A;  4JWG A;  3KNU A;  1OY5 A;  4CNG A;  1UAM A;  4YQQ A;  3WRP A;  3NK6 A;  4KGN A;  5GMB A;  1J85 A;  4YPW A;  3ONP A;  4YQB A;  4J3C A;  2OZ9 R;  4X3M A;  3SSW N;  1MI7 R;  4YQJ A;  4YVI A;  4YQA A;  4YQP A;  2V3K A;  3OIJ A;  1UAK A;  3BBE A;  3N4K A;  3N4J A;  4YVJ A;  2EGW A;  2Z0Y A;  4YQ5 A;  2HA8 A;  4YQ7 A;  1K3R A;  5GM8 A;  4YQN A;  1UAJ A;  4YQL A;  3KTY A;  1WRT R;  4YQ6 A;  5GMC A;  1NXZ A;  1P9P A;  2QMM A;  2XDI A;  4YQR A;  2O3A A;  2I6D A;  4JWF A;  4YQD A;  1X7P A;  4YQ3 A;  4YVK A;  4MCD A;  1VHK A;  3KW2 A;  3AXZ A;  3G1C A;  4PZK A;  3NK7 A;  1V6Z A;  1IPA A;  4MCC A; 
#chains in the Genus database with same CATH homology
 1UAL A;  4YQG A;  2EGV A;  3E5Y A;  3ILK A;  4YQS A;  4YPY A;  4YQ2 A;  3L8U A;  5FAI A;  2CX8 A;  4YPX A;  4KDZ A;  4E8B A;  3DCM X;  1V2X A;  3QUV A;  1VH0 A;  4JWH A;  3IC6 A;  1TO0 A;  4L69 A;  4JAK A;  4YQ9 A;  4YQ0 A;  4YPZ A;  4YQO A;  4YQI A;  4YQ8 A;  4H3Y A;  4YVG A;  3BBD A;  4JAL A;  5D9F A;  4JWJ A;  2V3J A;  3GYQ A;  1O6D A;  4FMW A;  4H3Z A;  3O7B A;  4CNF A;  4YQ4 A;  1MXI A;  3OIN A;  4FAK A;  1VHY A;  1ZJR A;  2QWV A;  2YY8 A;  3OII A;  4MCB A;  4CNE A;  4IG6 A;  1X7O A;  1NS5 A;  4YQC A;  3BBH A;  4X3L A;  4XBO A;  3AIA A;  3KY7 A;  4YVH A;  3AI9 X;  4RG1 A;  4YQ1 A;  3IEF A;  1GZ0 A;  5CO4 A;  4CND A;  4YQK A;  1Z85 A;  4YQT A;  4JWG A;  3KNU A;  1OY5 A;  4CNG A;  1UAM A;  4YQQ A;  3NK6 A;  4KGN A;  5GMB A;  1J85 A;  4YPW A;  3ONP A;  4YQB A;  4J3C A;  4X3M A;  4YQJ A;  4YVI A;  4YQA A;  4YQP A;  2V3K A;  3OIJ A;  1UAK A;  3BBE A;  3N4K A;  3N4J A;  4YVJ A;  2EGW A;  2Z0Y A;  4YQ5 A;  2HA8 A;  4YQ7 A;  1K3R A;  5GM8 A;  4YQN A;  1UAJ A;  4YQL A;  3KTY A;  4YQ6 A;  5GMC A;  1NXZ A;  1P9P A;  2QMM A;  4YQR A;  2O3A A;  2I6D A;  4JWF A;  4YQD A;  1X7P A;  4YQ3 A;  4YVK A;  4MCD A;  1VHK A;  3KW2 A;  3AXZ A;  4PZK A;  3NK7 A;  1V6Z A;  1IPA A;  4MCC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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