4YVKA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna variant (g36c)
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 68
structure length 239
sequence length 248
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvkA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvkA01
1V6ZA 4YQ0A 1VHKA 5D9FA 4YQLA 2QWVA 3N4KA 4H3YA 3IC6A 5GMCA 3AIAA 4YVIA 2QMMA 3ONPA 2V3KA 4KDZA 4YQTA 4X3MA 3ILKA 1NXZA 4YQAA 1UAKA 1UAMA 4YPYA 3GYQA 4YPXA 2HA8A 1IPAA 4YQJA 2O3AA 2I6DA 4J3CA 4YQ4A 1MXIA 1VHYA 3KTYA 5GMBA 4YQKA 4YQ6A 3KY7A 1V2XA 4YQGA 4YPZA 4YQPA 4YVHA 4L69A 4CNFA 4YPWA 4YQRA 1Z85A 3KNUA 2EGWA 1TO0A 2EGVA 1ZJRA 1X7PA 4CNDA 5FAIA 3DCMX 4YVKA 4JAKA 4YQSA 5CO4A 4YQCA 4YQ1A 1O6DA 4YQQA 3KW2A 3IEFA 4YVGA 2CX8A 4YQDA 4YQOA 3E5YA 4YQ3A 1K3RA 4MCBA 1GZ0A 3OINA 3BBDA 2Z0YA 4RG1A 4YQ2A 4XBOA 3AXZA 4MCDA 4KGNA 4YQ8A 5GM8A 4CNGA 3NK6A 3OIIA 3QUVA 1J85A 1NS5A 3BBHA 4YQBA 4E8BA 4YQ7A 4MCCA 2V3JA 2YY8A 1X7OA 4PZKA 4FAKA 4YQ5A 4YQ9A 4X3LA 4H3ZA 4YQNA 4IG6A 3NK7A 4JALA 3L8UA 3N4JA 1UALA 4YQIA 3OIJA 3O7BA 1UAJA 1VH0A 4CNEA 1OY5A 4YVJA 3AI9X 3BBEA 1P9PA
chains in the Genus database with same CATH superfamily
1V6ZA 4YQ0A 1VHKA 5D9FA 4YQLA 1JHGA 2QWVA 3N4KA 4H3YA 3IC6A 5GMCA 3AIAA 4YVIA 2QMMA 3ONPA 2V3KA 4KDZA 4YQTA 4X3MA 4JWHA 3ILKA 1NXZA 4YQAA 1UAKA 1UAMA 4YPYA 2OZ9R 3GYQA 4YPXA 2HA8A 1IPAA 4YQJA 2O3AA 2I6DA 4J3CA 3G1CA 4YQ4A 1MXIA 1VHYA 3KTYA 5GMBA 4YQKA 4YQ6A 3KY7A 1V2XA 4YQGA 4YPZA 4YQPA 4YVHA 4L69A 3KORA 4CNFA 3FRWA 4YPWA 4YQRA 1CO0A 1Z85A 3KNUA 2EGWA 1TO0A 2EGVA 1ZJRA 1X7PA 4CNDA 3SSWN 5FAIA 3DCMX 4YVKA 4JAKA 4YQSA 5CO4A 4YQCA 4YQ1A 4YQQA 1O6DA 3KW2A 3IEFA 1RCSA 4YVGA 2CX8A 4YQDA 4YQOA 3E5YA 4YQ3A 1K3RA 4MCBA 1GZ0A 3OINA 3WRPA 3BBDA 2Z0YA 4RG1A 4YQ2A 4XBOA 3AXZA 4MCDA 4KGNA 2XDIA 4YQ8A 5GM8A 4CNGA 3NK6A 1WRTR 3OIIA 4FMWA 3QUVA 1J85A 1NS5A 3BBHA 4YQBA 4E8BA 4YQ7A 4MCCA 4JWJA 2V3JA 3SSXN 1MI7R 2YY8A 1X7OA 4PZKA 1WRSR 4YQ5A 4YQ9A 4FAKA 4X3LA 4H3ZA 4YQNA 4IG6A 3NK7A 4JWFA 4JALA 3L8UA 3N4JA 1UALA 4YQIA 3OIJA 3O7BA 1TRRA 1UAJA 1VH0A 1WRPR 1TROA 4CNEA 1OY5A 4YVJA 3AI9X 1ZT9A 4JWGA 3BBEA 1P9PA
chains in the Genus database with same CATH topology
1V6ZA 4YQ0A 1VHKA 5D9FA 4YQLA 2QWVA 3N4KA 4H3YA 3IC6A 5GMCA 3AIAA 4YVIA 2QMMA 3ONPA 2V3KA 4KDZA 4YQTA 4X3MA 4JWHA 3ILKA 1NXZA 4YQAA 1UAKA 1UAMA 4YPYA 3GYQA 4YPXA 2HA8A 1IPAA 4YQJA 2O3AA 2I6DA 4J3CA 4YQ4A 1MXIA 1VHYA 3KTYA 5GMBA 4YQKA 4YQ6A 3KY7A 1V2XA 4YQGA 4YPZA 4YQPA 4YVHA 4L69A 4CNFA 4YPWA 4YQRA 1Z85A 3KNUA 2EGWA 1TO0A 2EGVA 1ZJRA 1X7PA 4CNDA 5FAIA 3DCMX 4YVKA 4JAKA 4YQSA 5CO4A 4YQCA 4YQ1A 1O6DA 4YQQA 3KW2A 3IEFA 4YVGA 2CX8A 4YQDA 4YQOA 3E5YA 4YQ3A 1K3RA 4MCBA 1GZ0A 3OINA 3BBDA 2Z0YA 4RG1A 4YQ2A 4XBOA 3AXZA 4MCDA 4KGNA 4YQ8A 5GM8A 4CNGA 3NK6A 3OIIA 4FMWA 3QUVA 1J85A 1NS5A 3BBHA 4YQBA 4E8BA 4YQ7A 4MCCA 4JWJA 2V3JA 2YY8A 1X7OA 4PZKA 4FAKA 4YQ5A 4YQ9A 4X3LA 4H3ZA 4YQNA 4IG6A 3NK7A 4JWFA 4JALA 3L8UA 3N4JA 1UALA 4YQIA 3OIJA 3O7BA 1UAJA 1VH0A 4CNEA 1OY5A 4YVJA 3AI9X 4JWGA 3BBEA 1P9PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V6Z A;  4YQ0 A;  1VHK A;  5D9F A;  4YQL A;  2QWV A;  3N4K A;  4H3Y A;  3IC6 A;  5GMC A;  3AIA A;  4YVI A;  2QMM A;  3ONP A;  2V3K A;  4KDZ A;  4YQT A;  4X3M A;  3ILK A;  1NXZ A;  4YQA A;  1UAK A;  1UAM A;  4YPY A;  3GYQ A;  4YPX A;  2HA8 A;  1IPA A;  4YQJ A;  2O3A A;  2I6D A;  4J3C A;  4YQ4 A;  1MXI A;  1VHY A;  3KTY A;  5GMB A;  4YQK A;  4YQ6 A;  3KY7 A;  1V2X A;  4YQG A;  4YPZ A;  4YQP A;  4YVH A;  4L69 A;  4CNF A;  4YPW A;  4YQR A;  1Z85 A;  3KNU A;  2EGW A;  1TO0 A;  2EGV A;  1ZJR A;  1X7P A;  4CND A;  5FAI A;  3DCM X;  4YVK A;  4JAK A;  4YQS A;  5CO4 A;  4YQC A;  4YQ1 A;  1O6D A;  4YQQ A;  3KW2 A;  3IEF A;  4YVG A;  2CX8 A;  4YQD A;  4YQO A;  3E5Y A;  4YQ3 A;  1K3R A;  4MCB A;  1GZ0 A;  3OIN A;  3BBD A;  2Z0Y A;  4RG1 A;  4YQ2 A;  4XBO A;  3AXZ A;  4MCD A;  4KGN A;  4YQ8 A;  5GM8 A;  4CNG A;  3NK6 A;  3OII A;  3QUV A;  1J85 A;  1NS5 A;  3BBH A;  4YQB A;  4E8B A;  4YQ7 A;  4MCC A;  2V3J A;  2YY8 A;  1X7O A;  4PZK A;  4FAK A;  4YQ5 A;  4YQ9 A;  4X3L A;  4H3Z A;  4YQN A;  4IG6 A;  3NK7 A;  4JAL A;  3L8U A;  3N4J A;  1UAL A;  4YQI A;  3OIJ A;  3O7B A;  1UAJ A;  1VH0 A;  4CNE A;  1OY5 A;  4YVJ A;  3AI9 X;  3BBE A;  1P9P A; 
#chains in the Genus database with same CATH topology
 1V6Z A;  4YQ0 A;  1VHK A;  5D9F A;  4YQL A;  1JHG A;  2QWV A;  3N4K A;  4H3Y A;  3IC6 A;  5GMC A;  3AIA A;  4YVI A;  2QMM A;  3ONP A;  2V3K A;  4KDZ A;  4YQT A;  4X3M A;  4JWH A;  3ILK A;  1NXZ A;  4YQA A;  1UAK A;  1UAM A;  4YPY A;  2OZ9 R;  3GYQ A;  4YPX A;  2HA8 A;  1IPA A;  4YQJ A;  2O3A A;  2I6D A;  4J3C A;  3G1C A;  4YQ4 A;  1MXI A;  1VHY A;  3KTY A;  5GMB A;  4YQK A;  4YQ6 A;  3KY7 A;  1V2X A;  4YQG A;  4YPZ A;  4YQP A;  4YVH A;  4L69 A;  3KOR A;  4CNF A;  3FRW A;  4YPW A;  4YQR A;  1CO0 A;  1Z85 A;  3KNU A;  2EGW A;  1TO0 A;  2EGV A;  1ZJR A;  1X7P A;  4CND A;  3SSW N;  5FAI A;  3DCM X;  4YVK A;  4JAK A;  4YQS A;  5CO4 A;  4YQC A;  4YQ1 A;  4YQQ A;  1O6D A;  3KW2 A;  3IEF A;  1RCS A;  4YVG A;  2CX8 A;  4YQD A;  4YQO A;  3E5Y A;  4YQ3 A;  1K3R A;  4MCB A;  1GZ0 A;  3OIN A;  3WRP A;  3BBD A;  2Z0Y A;  4RG1 A;  4YQ2 A;  4XBO A;  3AXZ A;  4MCD A;  4KGN A;  2XDI A;  4YQ8 A;  5GM8 A;  4CNG A;  3NK6 A;  1WRT R;  3OII A;  4FMW A;  3QUV A;  1J85 A;  1NS5 A;  3BBH A;  4YQB A;  4E8B A;  4YQ7 A;  4MCC A;  4JWJ A;  2V3J A;  3SSX N;  1MI7 R;  2YY8 A;  1X7O A;  4PZK A;  1WRS R;  4YQ5 A;  4YQ9 A;  4FAK A;  4X3L A;  4H3Z A;  4YQN A;  4IG6 A;  3NK7 A;  4JWF A;  4JAL A;  3L8U A;  3N4J A;  1UAL A;  4YQI A;  3OIJ A;  3O7B A;  1TRR A;  1UAJ A;  1VH0 A;  1WRP R;  1TRO A;  4CNE A;  1OY5 A;  4YVJ A;  3AI9 X;  1ZT9 A;  4JWG A;  3BBE A;  1P9P A; 
#chains in the Genus database with same CATH homology
 1V6Z A;  4YQ0 A;  1VHK A;  5D9F A;  4YQL A;  2QWV A;  3N4K A;  4H3Y A;  3IC6 A;  5GMC A;  3AIA A;  4YVI A;  2QMM A;  3ONP A;  2V3K A;  4KDZ A;  4YQT A;  4X3M A;  4JWH A;  3ILK A;  1NXZ A;  4YQA A;  1UAK A;  1UAM A;  4YPY A;  3GYQ A;  4YPX A;  2HA8 A;  1IPA A;  4YQJ A;  2O3A A;  2I6D A;  4J3C A;  4YQ4 A;  1MXI A;  1VHY A;  3KTY A;  5GMB A;  4YQK A;  4YQ6 A;  3KY7 A;  1V2X A;  4YQG A;  4YPZ A;  4YQP A;  4YVH A;  4L69 A;  4CNF A;  4YPW A;  4YQR A;  1Z85 A;  3KNU A;  2EGW A;  1TO0 A;  2EGV A;  1ZJR A;  1X7P A;  4CND A;  5FAI A;  3DCM X;  4YVK A;  4JAK A;  4YQS A;  5CO4 A;  4YQC A;  4YQ1 A;  1O6D A;  4YQQ A;  3KW2 A;  3IEF A;  4YVG A;  2CX8 A;  4YQD A;  4YQO A;  3E5Y A;  4YQ3 A;  1K3R A;  4MCB A;  1GZ0 A;  3OIN A;  3BBD A;  2Z0Y A;  4RG1 A;  4YQ2 A;  4XBO A;  3AXZ A;  4MCD A;  4KGN A;  4YQ8 A;  5GM8 A;  4CNG A;  3NK6 A;  3OII A;  4FMW A;  3QUV A;  1J85 A;  1NS5 A;  3BBH A;  4YQB A;  4E8B A;  4YQ7 A;  4MCC A;  4JWJ A;  2V3J A;  2YY8 A;  1X7O A;  4PZK A;  4FAK A;  4YQ5 A;  4YQ9 A;  4X3L A;  4H3Z A;  4YQN A;  4IG6 A;  3NK7 A;  4JWF A;  4JAL A;  3L8U A;  3N4J A;  1UAL A;  4YQI A;  3OIJ A;  3O7B A;  1UAJ A;  1VH0 A;  4CNE A;  1OY5 A;  4YVJ A;  3AI9 X;  4JWG A;  3BBE A;  1P9P A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...