5D9FA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 5d9fA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 5d9fA01
4YQ9A 4MCDA 4YQOA 4YQLA 5GMCA 3OIIA 4YQKA 4CNDA 3N4KA 3KY7A 1MXIA 3DCMX 5GM8A 4YQSA 1NS5A 2V3JA 4H3YA 4YPXA 1O6DA 2QMMA 4CNEA 4YQ2A 2I6DA 4YQ0A 4YQ4A 1UAJA 2HA8A 2QWVA 3NK7A 5CO4A 4YVIA 2O3AA 3IC6A 4MCBA 1GZ0A 3OINA 4YVHA 1K3RA 3AI9X 3O7BA 4X3MA 4YPZA 3BBHA 4CNGA 3ONPA 3KTYA 3IEFA 4YQRA 4YQNA 4YVKA 3L8UA 4YQJA 4XBOA 4PZKA 5D9FA 4YQ6A 1V2XA 1J85A 4MCCA 1P9PA 1UALA 3AIAA 5GMBA 4E8BA 4YQGA 3QUVA 1OY5A 4YQTA 1NXZA 4YQAA 1VH0A 3OIJA 2Z0YA 2CX8A 3BBDA 1TO0A 4YQBA 4YQQA 2EGWA 2YY8A 4YQPA 3N4JA 4JAKA 3AXZA 2EGVA 3E5YA 4YQCA 3BBEA 4YQ7A 4X3LA 4IG6A 4YVJA 4YVGA 4YPYA 1ZJRA 4RG1A 4YQ8A 4JALA 1VHKA 1V6ZA 1VHYA 3NK6A 4YQ5A 5FAIA 1UAMA 4YQ3A 3ILKA 4L69A 1X7OA 1X7PA 4YQDA 1IPAA 4J3CA 4FAKA 3GYQA 4KGNA 2V3KA 4KDZA 4YPWA 3KW2A 1UAKA 4YQ1A 4H3ZA 3KNUA 4CNFA 4YQIA 1Z85A
chains in the Genus database with same CATH superfamily
4YQ9A 4MCDA 4YQOA 3SSWN 4YQLA 5GMCA 3OIIA 4YQKA 4CNDA 3N4KA 3SSXN 3KY7A 1MXIA 3DCMX 5GM8A 1WRPR 1WRTR 3FRWA 4YQSA 3WRPA 1NS5A 2V3JA 4H3YA 4YPXA 1TROA 1JHGA 1O6DA 2QMMA 4CNEA 4YQ2A 2I6DA 4YQ0A 4YQ4A 1UAJA 1MI7R 2HA8A 2QWVA 3NK7A 5CO4A 4YVIA 2O3AA 3IC6A 4MCBA 1GZ0A 3OINA 4YVHA 1K3RA 3AI9X 3O7BA 4X3MA 4YPZA 4JWGA 3BBHA 4CNGA 3ONPA 3KTYA 3IEFA 4YQRA 4YQNA 4YVKA 3L8UA 4YQJA 4XBOA 4PZKA 5D9FA 4YQ6A 1V2XA 1J85A 1ZT9A 4MCCA 1P9PA 1UALA 4JWJA 3AIAA 5GMBA 4E8BA 4YQGA 1WRSR 4JWHA 3QUVA 2XDIA 1OY5A 4YQTA 1NXZA 4YQAA 1VH0A 3OIJA 2Z0YA 2CX8A 3BBDA 1TO0A 4YQBA 2OZ9R 4YQQA 1RCSA 2EGWA 2YY8A 4YQPA 3N4JA 4JAKA 3AXZA 3KORA 2EGVA 1TRRA 3E5YA 4YQCA 3BBEA 4YQ7A 4X3LA 4IG6A 1CO0A 4YVJA 4YVGA 3G1CA 4YPYA 1ZJRA 4RG1A 4YQ8A 4JALA 1VHKA 1V6ZA 1VHYA 3NK6A 4YQ5A 5FAIA 1UAMA 4YQ3A 3ILKA 4L69A 1X7OA 1X7PA 4YQDA 4JWFA 1IPAA 4FMWA 4J3CA 4FAKA 3GYQA 4KGNA 2V3KA 4KDZA 4YPWA 3KW2A 1UAKA 4YQ1A 4H3ZA 3KNUA 4CNFA 4YQIA 1Z85A
chains in the Genus database with same CATH topology
4YQ9A 4MCDA 4YQOA 4YQLA 5GMCA 3OIIA 4YQKA 4CNDA 3N4KA 3KY7A 1MXIA 3DCMX 5GM8A 4YQSA 1NS5A 2V3JA 4H3YA 4YPXA 1O6DA 2QMMA 4CNEA 4YQ2A 2I6DA 4YQ0A 4YQ4A 1UAJA 2HA8A 2QWVA 3NK7A 5CO4A 4YVIA 2O3AA 3IC6A 4MCBA 1GZ0A 3OINA 4YVHA 1K3RA 3AI9X 3O7BA 4X3MA 4YPZA 4JWGA 3BBHA 4CNGA 3ONPA 3KTYA 3IEFA 4YQRA 4YQNA 4YVKA 3L8UA 4YQJA 4XBOA 4PZKA 5D9FA 4YQ6A 1V2XA 1J85A 4MCCA 1P9PA 1UALA 4JWJA 3AIAA 5GMBA 4E8BA 4YQGA 4JWHA 3QUVA 1OY5A 4YQTA 1NXZA 4YQAA 1VH0A 3OIJA 2Z0YA 2CX8A 3BBDA 1TO0A 4YQBA 4YQQA 2EGWA 2YY8A 4YQPA 3N4JA 4JAKA 3AXZA 2EGVA 3E5YA 4YQCA 3BBEA 4YQ7A 4X3LA 4IG6A 4YVJA 4YVGA 4YPYA 1ZJRA 4RG1A 4YQ8A 4JALA 1VHKA 1V6ZA 1VHYA 3NK6A 4YQ5A 5FAIA 1UAMA 4YQ3A 3ILKA 4L69A 1X7OA 1X7PA 4YQDA 4JWFA 1IPAA 4FMWA 4J3CA 4FAKA 3GYQA 4KGNA 2V3KA 4KDZA 4YPWA 3KW2A 1UAKA 4YQ1A 4H3ZA 3KNUA 4CNFA 4YQIA 1Z85A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ9 A;  4MCD A;  4YQO A;  4YQL A;  5GMC A;  3OII A;  4YQK A;  4CND A;  3N4K A;  3KY7 A;  1MXI A;  3DCM X;  5GM8 A;  4YQS A;  1NS5 A;  2V3J A;  4H3Y A;  4YPX A;  1O6D A;  2QMM A;  4CNE A;  4YQ2 A;  2I6D A;  4YQ0 A;  4YQ4 A;  1UAJ A;  2HA8 A;  2QWV A;  3NK7 A;  5CO4 A;  4YVI A;  2O3A A;  3IC6 A;  4MCB A;  1GZ0 A;  3OIN A;  4YVH A;  1K3R A;  3AI9 X;  3O7B A;  4X3M A;  4YPZ A;  3BBH A;  4CNG A;  3ONP A;  3KTY A;  3IEF A;  4YQR A;  4YQN A;  4YVK A;  3L8U A;  4YQJ A;  4XBO A;  4PZK A;  5D9F A;  4YQ6 A;  1V2X A;  1J85 A;  4MCC A;  1P9P A;  1UAL A;  3AIA A;  5GMB A;  4E8B A;  4YQG A;  3QUV A;  1OY5 A;  4YQT A;  1NXZ A;  4YQA A;  1VH0 A;  3OIJ A;  2Z0Y A;  2CX8 A;  3BBD A;  1TO0 A;  4YQB A;  4YQQ A;  2EGW A;  2YY8 A;  4YQP A;  3N4J A;  4JAK A;  3AXZ A;  2EGV A;  3E5Y A;  4YQC A;  3BBE A;  4YQ7 A;  4X3L A;  4IG6 A;  4YVJ A;  4YVG A;  4YPY A;  1ZJR A;  4RG1 A;  4YQ8 A;  4JAL A;  1VHK A;  1V6Z A;  1VHY A;  3NK6 A;  4YQ5 A;  5FAI A;  1UAM A;  4YQ3 A;  3ILK A;  4L69 A;  1X7O A;  1X7P A;  4YQD A;  1IPA A;  4J3C A;  4FAK A;  3GYQ A;  4KGN A;  2V3K A;  4KDZ A;  4YPW A;  3KW2 A;  1UAK A;  4YQ1 A;  4H3Z A;  3KNU A;  4CNF A;  4YQI A;  1Z85 A; 
#chains in the Genus database with same CATH topology
 4YQ9 A;  4MCD A;  4YQO A;  3SSW N;  4YQL A;  5GMC A;  3OII A;  4YQK A;  4CND A;  3N4K A;  3SSX N;  3KY7 A;  1MXI A;  3DCM X;  5GM8 A;  1WRP R;  1WRT R;  3FRW A;  4YQS A;  3WRP A;  1NS5 A;  2V3J A;  4H3Y A;  4YPX A;  1TRO A;  1JHG A;  1O6D A;  2QMM A;  4CNE A;  4YQ2 A;  2I6D A;  4YQ0 A;  4YQ4 A;  1UAJ A;  1MI7 R;  2HA8 A;  2QWV A;  3NK7 A;  5CO4 A;  4YVI A;  2O3A A;  3IC6 A;  4MCB A;  1GZ0 A;  3OIN A;  4YVH A;  1K3R A;  3AI9 X;  3O7B A;  4X3M A;  4YPZ A;  4JWG A;  3BBH A;  4CNG A;  3ONP A;  3KTY A;  3IEF A;  4YQR A;  4YQN A;  4YVK A;  3L8U A;  4YQJ A;  4XBO A;  4PZK A;  5D9F A;  4YQ6 A;  1V2X A;  1J85 A;  1ZT9 A;  4MCC A;  1P9P A;  1UAL A;  4JWJ A;  3AIA A;  5GMB A;  4E8B A;  4YQG A;  1WRS R;  4JWH A;  3QUV A;  2XDI A;  1OY5 A;  4YQT A;  1NXZ A;  4YQA A;  1VH0 A;  3OIJ A;  2Z0Y A;  2CX8 A;  3BBD A;  1TO0 A;  4YQB A;  2OZ9 R;  4YQQ A;  1RCS A;  2EGW A;  2YY8 A;  4YQP A;  3N4J A;  4JAK A;  3AXZ A;  3KOR A;  2EGV A;  1TRR A;  3E5Y A;  4YQC A;  3BBE A;  4YQ7 A;  4X3L A;  4IG6 A;  1CO0 A;  4YVJ A;  4YVG A;  3G1C A;  4YPY A;  1ZJR A;  4RG1 A;  4YQ8 A;  4JAL A;  1VHK A;  1V6Z A;  1VHY A;  3NK6 A;  4YQ5 A;  5FAI A;  1UAM A;  4YQ3 A;  3ILK A;  4L69 A;  1X7O A;  1X7P A;  4YQD A;  4JWF A;  1IPA A;  4FMW A;  4J3C A;  4FAK A;  3GYQ A;  4KGN A;  2V3K A;  4KDZ A;  4YPW A;  3KW2 A;  1UAK A;  4YQ1 A;  4H3Z A;  3KNU A;  4CNF A;  4YQI A;  1Z85 A; 
#chains in the Genus database with same CATH homology
 4YQ9 A;  4MCD A;  4YQO A;  4YQL A;  5GMC A;  3OII A;  4YQK A;  4CND A;  3N4K A;  3KY7 A;  1MXI A;  3DCM X;  5GM8 A;  4YQS A;  1NS5 A;  2V3J A;  4H3Y A;  4YPX A;  1O6D A;  2QMM A;  4CNE A;  4YQ2 A;  2I6D A;  4YQ0 A;  4YQ4 A;  1UAJ A;  2HA8 A;  2QWV A;  3NK7 A;  5CO4 A;  4YVI A;  2O3A A;  3IC6 A;  4MCB A;  1GZ0 A;  3OIN A;  4YVH A;  1K3R A;  3AI9 X;  3O7B A;  4X3M A;  4YPZ A;  4JWG A;  3BBH A;  4CNG A;  3ONP A;  3KTY A;  3IEF A;  4YQR A;  4YQN A;  4YVK A;  3L8U A;  4YQJ A;  4XBO A;  4PZK A;  5D9F A;  4YQ6 A;  1V2X A;  1J85 A;  4MCC A;  1P9P A;  1UAL A;  4JWJ A;  3AIA A;  5GMB A;  4E8B A;  4YQG A;  4JWH A;  3QUV A;  1OY5 A;  4YQT A;  1NXZ A;  4YQA A;  1VH0 A;  3OIJ A;  2Z0Y A;  2CX8 A;  3BBD A;  1TO0 A;  4YQB A;  4YQQ A;  2EGW A;  2YY8 A;  4YQP A;  3N4J A;  4JAK A;  3AXZ A;  2EGV A;  3E5Y A;  4YQC A;  3BBE A;  4YQ7 A;  4X3L A;  4IG6 A;  4YVJ A;  4YVG A;  4YPY A;  1ZJR A;  4RG1 A;  4YQ8 A;  4JAL A;  1VHK A;  1V6Z A;  1VHY A;  3NK6 A;  4YQ5 A;  5FAI A;  1UAM A;  4YQ3 A;  3ILK A;  4L69 A;  1X7O A;  1X7P A;  4YQD A;  4JWF A;  1IPA A;  4FMW A;  4J3C A;  4FAK A;  3GYQ A;  4KGN A;  2V3K A;  4KDZ A;  4YPW A;  3KW2 A;  1UAK A;  4YQ1 A;  4H3Z A;  3KNU A;  4CNF A;  4YQI A;  1Z85 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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