1D3VA

Crystal structure of the binuclear manganese metalloenzyme arginase complexed with 2(s)-amino-6-boronohexanoic acid, an l-arginine analog
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
308
structure length
308
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arginase-boronic acid complex highlights a physiological role in erectile function.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords PROTEIN (ARGINASE)
total genus 108
structure length 308
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1d3vA00
4Q3RA 3THJA 3NIOA 5RLAA 3NIPA 4IU0A 2EF4A 3GN0A 4RHJA 4IXUA 4MYKA 3MMRA 3SJTA 1WVAA 2RLAA 4G3HA 4MXRA 1WOHA 1R1OA 4IE1A 5HJ9A 2AEBA 4IU1A 3TH7A 1HQHA 1P8QA 1T5GA 3LHLA 2EIVA 3MJLA 3SL1A 4RHKA 1HQ5A 2A0MA 4HZEA 4Q3TA 3GMZA 4Q3PA 5HJAA 3E6KA 3MFWA 4GSZA 4FCIA 4Q3QA 1RLAA 1T4PA 4HWWA 1PQ3A 3E9BA 4I06A 4IE3A 3TF3A 1GQ7A 4Q3SA 4MYLA 1P8NA 1TA1A 1TBJA 2PLLA 3THEA 3E6VA 1P8OA 4Q3VA 3LP7A 3PZLA 4RLAA 3RLAA 4FCKA 3E8QA 3SL0A 4DZ4A 1P8SA 1ZPGA 3SKKA 2ZAVA 1ZPEA 5CEVA 1P8RA 4Q3RC 4MYNA 1T4TA 4MYFA 1T4SA 1T4RA 4IXVA 4GWCA 1TBHA 1D3VA 3NIQA 2PHAA 4Q40A 1WOIA 1HQGA 1WOGA 1WVBA 1P8MA 1T5FA 4IU5A 4GSMA 1TBLA 4RHLA 1HQFA 4Q3UA 4IE2A 4RHMA 1XFKA 4RHQA 3THHA 4GWDA 3MFVA 4Q41A 3DJ8A 4CEVA 3E8ZA 4GSVA 1GQ6A 1CEVA 3LP4A 2EF5A 2PHOA 3CEVA 4IU4A 4RHIA 1HQXA 4Q42A 4HXQA 4ITYA 1P8PA 3F80A 2CEVA 3M1RA 3KV2A
chains in the Genus database with same CATH superfamily
3MZ4A 4Q3RA 3THJA 3NIOA 2VQVA 5RLAA 5G10A 1ZZ0A 5A2SA 3Q9CA 4ZURA 3NIPA 4IU0A 5G0YA 5D1DA 2EF4A 3GN0A 4QA3A 3F0RA 4ZUQA 4QA1A 4RN0A 4RHJA 5IX0A 4IXUA 4MYKA 3MMRA 3Q9BA 3SJTA 1WVAA 2RLAA 4G3HA 4MXRA 3MZ3A 4ZUOA 5G12A 1WOHA 5EEIA 1R1OA 4IE1A 5HJ9A 2AEBA 4IU1A 3TH7A 1HQHA 1P8QA 1T64A 1T5GA 4LXZA 3LHLA 2EIVA 3Q9EA 5EFBD 3MJLA 3SL1A 4RHKA 3EW8A 3SFHA 1HQ5A 2A0MA 1ZZ1A 5DC8A 4HZEA 4Q3TA 3GMZA 4Q3PA 1VKGA 5G1BA 3F07A 4QA2A 5HJAA 4ZUNA 3E6KA 3MFWA 5ICNB 4GSZA 2VQWG 1W22A 4FCIA 5DC7A 5G13A 4Q3QA 1RLAA 1T4PA 3MZ6A 1PQ3A 3E9BA 4HWWA 4I06A 4IE3A 5EFHA 4CBTA 1GQ7A 4Q3SA 5G0XA 4ZUPA 4MYLA 1P8NA 5G1CA 1TA1A 1TBJA 4BZ5A 5THVA 2PLLA 4BZ6A 5G11A 4RN2A 5EFGA 3THEA 5EF7A 3E6VA 5THUA 1P8OA 2VCGA 2GH6A 3C0YA 4Q3VA 3LP7A 3PZLA 4QA4A 4RLAA 3MZ7A 1T69A 4FCKA 3Q9FA 3RLAA 3E8QA 5EFJD 3SL0A 4DZ4A 1P8SA 1ZPGA 5BWZA 3SKKA 3ZNRA 2ZAVA 5G17A 3SFFA 1ZPEA 1C3SA 3MENA 4BZ8A 5CEVA 3MAXA 5G3WA 5G0JA 4BKXB 1P8RA 1C3RA 3EZTA 4Q3RC 3F06A 2V5XA 1C3PA 4MYNA 5G0HA 3EZPA 1T4TA 5THTA 4MYFA 4RN1A 1T4SA 4QA5A 5G0GA 3RQDA 5EF8A 1T4RA 4IXVA 3ZNSA 5JI5A 5EEMA 4GWCA 4QA6A 1TBHA 5EENA 1D3VA 4CBYA 3NIQA 2PHAA 3C10A 4Q40A 1WOIA 2VQOA 5THSA 1HQGA 1WOGA 1WVBA 1P8MA 5LI3A 1T5FA 4IU5A 5FCWA 4GSMA 4A69A 1TBLA 4RHLA 1HQFA 4Q3UA 5FUEA 4IE2A 4RHMA 5D1CA 1XFKA 4LY1A 4QA7A 4RHQA 3THHA 4GWDA 5G1AA 5EEFA 3MFVA 4BZ7A 4Q41A 3DJ8A 3TF3A 2V5WA 3EWFA 4ZUMA 5DC6A 4QA0A 4CEVA 3E8ZA 4GSVA 1GQ6A 2VQMA 3C0ZA 1CEVA 3LP4A 5EFKB 2EF5A 2PHOA 3CEVA 5DC5A 5G0IA 2VQJA 4IU4A 2VQQA 5D1BA 4BZ9A 4CQFA 4RHIA 1ZZ3A 1HQXA 4Q42A 5IWGA 4HXQA 4ITYA 5EEKA 1P8PA 3F80A 2CEVA 5EFNA 3M1RA 1T67A 3KV2A
chains in the Genus database with same CATH topology
4Q3RA 3THJA 3NIOA 5RLAA 3NIPA 4IU0A 2EF4A 3GN0A 4RHJA 4IXUA 4MYKA 3MMRA 3SJTA 1WVAA 2RLAA 4G3HA 4MXRA 1WOHA 1R1OA 4IE1A 5HJ9A 2AEBA 4IU1A 3TH7A 1HQHA 1P8QA 1T5GA 3LHLA 2EIVA 3MJLA 3SL1A 4RHKA 1HQ5A 2A0MA 4HZEA 4Q3TA 3GMZA 4Q3PA 5HJAA 3E6KA 3MFWA 4GSZA 4FCIA 4Q3QA 1RLAA 1T4PA 4HWWA 1PQ3A 3E9BA 4I06A 4IE3A 3TF3A 1GQ7A 4Q3SA 4MYLA 1P8NA 1TA1A 1TBJA 2PLLA 3THEA 3E6VA 1P8OA 4Q3VA 3LP7A 3PZLA 4RLAA 3RLAA 4FCKA 3E8QA 3SL0A 4DZ4A 1P8SA 1ZPGA 3SKKA 2ZAVA 1ZPEA 5CEVA 1P8RA 4Q3RC 4MYNA 1T4TA 4MYFA 1T4SA 1T4RA 4IXVA 4GWCA 1TBHA 1D3VA 3NIQA 2PHAA 4Q40A 1WOIA 1HQGA 1WOGA 1WVBA 1P8MA 1T5FA 4IU5A 4GSMA 1TBLA 4RHLA 1HQFA 4Q3UA 4IE2A 4RHMA 1XFKA 4RHQA 3THHA 4GWDA 3MFVA 4Q41A 3DJ8A 4CEVA 3E8ZA 4GSVA 1GQ6A 1CEVA 3LP4A 2EF5A 2PHOA 3CEVA 4IU4A 4RHIA 1HQXA 4Q42A 4HXQA 4ITYA 1P8PA 3F80A 2CEVA 3M1RA 3KV2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q3R A;  3THJ A;  3NIO A;  5RLA A;  3NIP A;  4IU0 A;  2EF4 A;  3GN0 A;  4RHJ A;  4IXU A;  4MYK A;  3MMR A;  3SJT A;  1WVA A;  2RLA A;  4G3H A;  4MXR A;  1WOH A;  1R1O A;  4IE1 A;  5HJ9 A;  2AEB A;  4IU1 A;  3TH7 A;  1HQH A;  1P8Q A;  1T5G A;  3LHL A;  2EIV A;  3MJL A;  3SL1 A;  4RHK A;  1HQ5 A;  2A0M A;  4HZE A;  4Q3T A;  3GMZ A;  4Q3P A;  5HJA A;  3E6K A;  3MFW A;  4GSZ A;  4FCI A;  4Q3Q A;  1RLA A;  1T4P A;  4HWW A;  1PQ3 A;  3E9B A;  4I06 A;  4IE3 A;  3TF3 A;  1GQ7 A;  4Q3S A;  4MYL A;  1P8N A;  1TA1 A;  1TBJ A;  2PLL A;  3THE A;  3E6V A;  1P8O A;  4Q3V A;  3LP7 A;  3PZL A;  4RLA A;  3RLA A;  4FCK A;  3E8Q A;  3SL0 A;  4DZ4 A;  1P8S A;  1ZPG A;  3SKK A;  2ZAV A;  1ZPE A;  5CEV A;  1P8R A;  4Q3R C;  4MYN A;  1T4T A;  4MYF A;  1T4S A;  1T4R A;  4IXV A;  4GWC A;  1TBH A;  1D3V A;  3NIQ A;  2PHA A;  4Q40 A;  1WOI A;  1HQG A;  1WOG A;  1WVB A;  1P8M A;  1T5F A;  4IU5 A;  4GSM A;  1TBL A;  4RHL A;  1HQF A;  4Q3U A;  4IE2 A;  4RHM A;  1XFK A;  4RHQ A;  3THH A;  4GWD A;  3MFV A;  4Q41 A;  3DJ8 A;  4CEV A;  3E8Z A;  4GSV A;  1GQ6 A;  1CEV A;  3LP4 A;  2EF5 A;  2PHO A;  3CEV A;  4IU4 A;  4RHI A;  1HQX A;  4Q42 A;  4HXQ A;  4ITY A;  1P8P A;  3F80 A;  2CEV A;  3M1R A;  3KV2 A; 
#chains in the Genus database with same CATH topology
 3MZ4 A;  4Q3R A;  3THJ A;  3NIO A;  2VQV A;  5RLA A;  5G10 A;  1ZZ0 A;  5A2S A;  3Q9C A;  4ZUR A;  3NIP A;  4IU0 A;  5G0Y A;  5D1D A;  2EF4 A;  3GN0 A;  4QA3 A;  3F0R A;  4ZUQ A;  4QA1 A;  4RN0 A;  4RHJ A;  5IX0 A;  4IXU A;  4MYK A;  3MMR A;  3Q9B A;  3SJT A;  1WVA A;  2RLA A;  4G3H A;  4MXR A;  3MZ3 A;  4ZUO A;  5G12 A;  1WOH A;  5EEI A;  1R1O A;  4IE1 A;  5HJ9 A;  2AEB A;  4IU1 A;  3TH7 A;  1HQH A;  1P8Q A;  1T64 A;  1T5G A;  4LXZ A;  3LHL A;  2EIV A;  3Q9E A;  5EFB D;  3MJL A;  3SL1 A;  4RHK A;  3EW8 A;  3SFH A;  1HQ5 A;  2A0M A;  1ZZ1 A;  5DC8 A;  4HZE A;  4Q3T A;  3GMZ A;  4Q3P A;  1VKG A;  5G1B A;  3F07 A;  4QA2 A;  5HJA A;  4ZUN A;  3E6K A;  3MFW A;  5ICN B;  4GSZ A;  2VQW G;  1W22 A;  4FCI A;  5DC7 A;  5G13 A;  4Q3Q A;  1RLA A;  1T4P A;  3MZ6 A;  1PQ3 A;  3E9B A;  4HWW A;  4I06 A;  4IE3 A;  5EFH A;  4CBT A;  1GQ7 A;  4Q3S A;  5G0X A;  4ZUP A;  4MYL A;  1P8N A;  5G1C A;  1TA1 A;  1TBJ A;  4BZ5 A;  5THV A;  2PLL A;  4BZ6 A;  5G11 A;  4RN2 A;  5EFG A;  3THE A;  5EF7 A;  3E6V A;  5THU A;  1P8O A;  2VCG A;  2GH6 A;  3C0Y A;  4Q3V A;  3LP7 A;  3PZL A;  4QA4 A;  4RLA A;  3MZ7 A;  1T69 A;  4FCK A;  3Q9F A;  3RLA A;  3E8Q A;  5EFJ D;  3SL0 A;  4DZ4 A;  1P8S A;  1ZPG A;  5BWZ A;  3SKK A;  3ZNR A;  2ZAV A;  5G17 A;  3SFF A;  1ZPE A;  1C3S A;  3MEN A;  4BZ8 A;  5CEV A;  3MAX A;  5G3W A;  5G0J A;  4BKX B;  1P8R A;  1C3R A;  3EZT A;  4Q3R C;  3F06 A;  2V5X A;  1C3P A;  4MYN A;  5G0H A;  3EZP A;  1T4T A;  5THT A;  4MYF A;  4RN1 A;  1T4S A;  4QA5 A;  5G0G A;  3RQD A;  5EF8 A;  1T4R A;  4IXV A;  3ZNS A;  5JI5 A;  5EEM A;  4GWC A;  4QA6 A;  1TBH A;  5EEN A;  1D3V A;  4CBY A;  3NIQ A;  2PHA A;  3C10 A;  4Q40 A;  1WOI A;  2VQO A;  5THS A;  1HQG A;  1WOG A;  1WVB A;  1P8M A;  5LI3 A;  1T5F A;  4IU5 A;  5FCW A;  4GSM A;  4A69 A;  1TBL A;  4RHL A;  1HQF A;  4Q3U A;  5FUE A;  4IE2 A;  4RHM A;  5D1C A;  1XFK A;  4LY1 A;  4QA7 A;  4RHQ A;  3THH A;  4GWD A;  5G1A A;  5EEF A;  3MFV A;  4BZ7 A;  4Q41 A;  3DJ8 A;  3TF3 A;  2V5W A;  3EWF A;  4ZUM A;  5DC6 A;  4QA0 A;  4CEV A;  3E8Z A;  4GSV A;  1GQ6 A;  2VQM A;  3C0Z A;  1CEV A;  3LP4 A;  5EFK B;  2EF5 A;  2PHO A;  3CEV A;  5DC5 A;  5G0I A;  2VQJ A;  4IU4 A;  2VQQ A;  5D1B A;  4BZ9 A;  4CQF A;  4RHI A;  1ZZ3 A;  1HQX A;  4Q42 A;  5IWG A;  4HXQ A;  4ITY A;  5EEK A;  1P8P A;  3F80 A;  2CEV A;  5EFN A;  3M1R A;  1T67 A;  3KV2 A; 
#chains in the Genus database with same CATH homology
 4Q3R A;  3THJ A;  3NIO A;  5RLA A;  3NIP A;  4IU0 A;  2EF4 A;  3GN0 A;  4RHJ A;  4IXU A;  4MYK A;  3MMR A;  3SJT A;  1WVA A;  2RLA A;  4G3H A;  4MXR A;  1WOH A;  1R1O A;  4IE1 A;  5HJ9 A;  2AEB A;  4IU1 A;  3TH7 A;  1HQH A;  1P8Q A;  1T5G A;  3LHL A;  2EIV A;  3MJL A;  3SL1 A;  4RHK A;  1HQ5 A;  2A0M A;  4HZE A;  4Q3T A;  3GMZ A;  4Q3P A;  5HJA A;  3E6K A;  3MFW A;  4GSZ A;  4FCI A;  4Q3Q A;  1RLA A;  1T4P A;  4HWW A;  1PQ3 A;  3E9B A;  4I06 A;  4IE3 A;  3TF3 A;  1GQ7 A;  4Q3S A;  4MYL A;  1P8N A;  1TA1 A;  1TBJ A;  2PLL A;  3THE A;  3E6V A;  1P8O A;  4Q3V A;  3LP7 A;  3PZL A;  4RLA A;  3RLA A;  4FCK A;  3E8Q A;  3SL0 A;  4DZ4 A;  1P8S A;  1ZPG A;  3SKK A;  2ZAV A;  1ZPE A;  5CEV A;  1P8R A;  4Q3R C;  4MYN A;  1T4T A;  4MYF A;  1T4S A;  1T4R A;  4IXV A;  4GWC A;  1TBH A;  1D3V A;  3NIQ A;  2PHA A;  4Q40 A;  1WOI A;  1HQG A;  1WOG A;  1WVB A;  1P8M A;  1T5F A;  4IU5 A;  4GSM A;  1TBL A;  4RHL A;  1HQF A;  4Q3U A;  4IE2 A;  4RHM A;  1XFK A;  4RHQ A;  3THH A;  4GWD A;  3MFV A;  4Q41 A;  3DJ8 A;  4CEV A;  3E8Z A;  4GSV A;  1GQ6 A;  1CEV A;  3LP4 A;  2EF5 A;  2PHO A;  3CEV A;  4IU4 A;  4RHI A;  1HQX A;  4Q42 A;  4HXQ A;  4ITY A;  1P8P A;  3F80 A;  2CEV A;  3M1R A;  3KV2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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