1D3VA

Crystal structure of the binuclear manganese metalloenzyme arginase complexed with 2(s)-amino-6-boronohexanoic acid, an l-arginine analog
Total Genus 108
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
308
structure length
308
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Arginase-boronic acid complex highlights a physiological role in erectile function.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords PROTEIN (ARGINASE)
total genus 108
structure length 308
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1d3vA00
3MFVA 3E9BA 3MJLA 4I06A 2PHAA 1T4PA 3LP4A 1TBJA 1RLAA 1ZPEA 3MMRA 3M1RA 2EF5A 1HQGA 4MYLA 3E8ZA 1P8NA 4MYKA 2PHOA 1T4RA 1CEVA 3LHLA 4FCKA 4RLAA 4MYFA 1R1OA 3LP7A 3KV2A 1PQ3A 4HWWA 5CEVA 4IU4A 5RLAA 1T5GA 4GSZA 2CEVA 4DZ4A 1GQ6A 1TA1A 1HQFA 4Q3RA 4RHIA 4IE1A 3TF3A 1T5FA 3GMZA 3NIPA 4Q42A 3SKKA 4GSMA 3SJTA 4IU0A 2ZAVA 2EF4A 5HJAA 1WVAA 3NIQA 3E6VA 4ITYA 4Q3QA 4FCIA 3THEA 3SL0A 4IXUA 1XFKA 3SL1A 4CEVA 2PLLA 5HJ9A 1P8OA 1HQHA 4Q41A 3GN0A 1P8QA 4Q3VA 1GQ7A 4GWCA 1TBHA 1WOHA 2AEBA 3E6KA 4G3HA 4IE3A 2A0MA 4Q3PA 3E8QA 4HZEA 1ZPGA 4IU5A 4IU1A 4Q3RC 3RLAA 1P8MA 1TBLA 4RHLA 4RHKA 1P8SA 3TH7A 3F80A 3MFWA 4Q3UA 4IE2A 4MXRA 3THJA 1D3VA 4MYNA 3THHA 1P8RA 2RLAA 4HXQA 4IXVA 3DJ8A 4RHQA 1HQ5A 1WOGA 1WVBA 4RHMA 4Q3TA 4Q40A 1HQXA 4RHJA 4GSVA 2EIVA 4GWDA 3PZLA 3NIOA 1T4TA 1T4SA 1WOIA 3CEVA 1P8PA 4Q3SA
chains in the Genus database with same CATH superfamily
3MFVA 3E9BA 4ZUOA 2V5WA 3MJLA 4I06A 2PHAA 1T4PA 3LP4A 1TBJA 4CBYA 3EZPA 1RLAA 1ZPEA 3MMRA 3SFHA 1T69A 2EF5A 1HQGA 3M1RA 4MYLA 5THSA 3E8ZA 2VQQA 5EFGA 1P8NA 4MYKA 3F07A 4BZ6A 2PHOA 1T4RA 1C3SA 1CEVA 3Q9FA 3C10A 3LHLA 4FCKA 1C3PA 2GH6A 2VCGA 4QA4A 4MYFA 4RLAA 4ZUNA 1R1OA 3LP7A 4QA1A 3MZ7A 5FCWA 3KV2A 3RQDA 4ZUQA 1PQ3A 3MENA 2VQVA 3Q9BA 4HWWA 3F0RA 5CEVA 1C3RA 4IU4A 2VQMA 5LI3A 5RLAA 5D1CA 4RN0A 1T5GA 5JI5A 2CEVA 4GSZA 5EEMA 4DZ4A 5G0YA 1GQ6A 5EEIA 5EFKB 3F06A 1TA1A 1HQFA 4Q3RA 4RHIA 5FUEA 4RN1A 5D1DA 4IE1A 5G0HA 5EENA 5G3WA 3C0ZA 5G10A 3TF3A 1T5FA 3GMZA 5G1CA 3NIPA 1ZZ0A 4Q42A 3SKKA 4GSMA 3SJTA 4IU0A 2ZAVA 5G1AA 3SFFA 4BZ7A 3EW8A 2EF4A 5EEFA 1WVAA 5HJAA 3EWFA 3NIQA 3E6VA 4ITYA 5EFHA 2VQJA 4Q3QA 4FCIA 4QA5A 5D1BA 5EEKA 4ZURA 5THUA 3THEA 5G0IA 5G12A 3SL0A 4IXUA 1XFKA 3SL1A 5G17A 4LXZA 4QA2A 3Q9CA 5G13A 5IX0A 5DC8A 4BZ9A 4CBTA 3MAXA 4CQFA 4CEVA 2PLLA 2VQOA 5HJ9A 2VQWG 1P8OA 5EFNA 1HQHA 4Q41A 3GN0A 1P8QA 4Q3VA 4BZ8A 1GQ7A 3ZNRA 5EF7A 4A69A 1VKGA 4GWCA 1TBHA 1WOHA 2AEBA 4QA0A 4RN2A 3E6KA 5DC5A 4G3HA 4IE3A 4BZ5A 1ZZ1A 5EFBD 2A0MA 4Q3PA 3E8QA 3Q9EA 4HZEA 1ZPGA 4IU5A 4IU1A 1ZZ3A 5G0GA 5G1BA 2V5XA 5THVA 4Q3RC 3RLAA 4ZUPA 4LY1A 1P8MA 4ZUMA 1TBLA 4RHLA 4RHKA 1P8SA 5EFJD 3TH7A 5EF8A 5G0JA 4QA3A 3MZ3A 3F80A 3MFWA 4Q3UA 3MZ6A 4BKXB 4IE2A 3MZ4A 4MXRA 3THJA 5BWZA 3ZNSA 4QA7A 4QA6A 1D3VA 4MYNA 3C0YA 1P8RA 2RLAA 3THHA 5ICNB 1T67A 4HXQA 5G0XA 1T64A 3DJ8A 4IXVA 4RHQA 5IWGA 1HQ5A 1WOGA 1WVBA 3EZTA 4RHMA 4Q3TA 4Q40A 5G11A 1HQXA 1W22A 4RHJA 4GSVA 2EIVA 5DC6A 4GWDA 5A2SA 3PZLA 3NIOA 1T4TA 1T4SA 1WOIA 3CEVA 1P8PA 5DC7A 4Q3SA 5THTA
chains in the Genus database with same CATH topology
3MFVA 3E9BA 3MJLA 4I06A 2PHAA 1T4PA 3LP4A 1TBJA 1RLAA 1ZPEA 3MMRA 3M1RA 2EF5A 1HQGA 4MYLA 3E8ZA 1P8NA 4MYKA 2PHOA 1T4RA 1CEVA 3LHLA 4FCKA 4RLAA 4MYFA 1R1OA 3LP7A 3KV2A 1PQ3A 4HWWA 5CEVA 4IU4A 5RLAA 1T5GA 4GSZA 2CEVA 4DZ4A 1GQ6A 1TA1A 1HQFA 4Q3RA 4RHIA 4IE1A 3TF3A 1T5FA 3GMZA 3NIPA 4Q42A 3SKKA 4GSMA 3SJTA 4IU0A 2ZAVA 2EF4A 5HJAA 1WVAA 3NIQA 3E6VA 4ITYA 4Q3QA 4FCIA 3THEA 3SL0A 4IXUA 1XFKA 3SL1A 4CEVA 2PLLA 5HJ9A 1P8OA 1HQHA 4Q41A 3GN0A 1P8QA 4Q3VA 1GQ7A 4GWCA 1TBHA 1WOHA 2AEBA 3E6KA 4G3HA 4IE3A 2A0MA 4Q3PA 3E8QA 4HZEA 1ZPGA 4IU5A 4IU1A 4Q3RC 3RLAA 1P8MA 1TBLA 4RHLA 4RHKA 1P8SA 3TH7A 3F80A 3MFWA 4Q3UA 4IE2A 4MXRA 3THJA 1D3VA 4MYNA 3THHA 1P8RA 2RLAA 4HXQA 4IXVA 3DJ8A 4RHQA 1HQ5A 1WOGA 1WVBA 4RHMA 4Q3TA 4Q40A 1HQXA 4RHJA 4GSVA 2EIVA 4GWDA 3PZLA 3NIOA 1T4TA 1T4SA 1WOIA 3CEVA 1P8PA 4Q3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MFV A;  3E9B A;  3MJL A;  4I06 A;  2PHA A;  1T4P A;  3LP4 A;  1TBJ A;  1RLA A;  1ZPE A;  3MMR A;  3M1R A;  2EF5 A;  1HQG A;  4MYL A;  3E8Z A;  1P8N A;  4MYK A;  2PHO A;  1T4R A;  1CEV A;  3LHL A;  4FCK A;  4RLA A;  4MYF A;  1R1O A;  3LP7 A;  3KV2 A;  1PQ3 A;  4HWW A;  5CEV A;  4IU4 A;  5RLA A;  1T5G A;  4GSZ A;  2CEV A;  4DZ4 A;  1GQ6 A;  1TA1 A;  1HQF A;  4Q3R A;  4RHI A;  4IE1 A;  3TF3 A;  1T5F A;  3GMZ A;  3NIP A;  4Q42 A;  3SKK A;  4GSM A;  3SJT A;  4IU0 A;  2ZAV A;  2EF4 A;  5HJA A;  1WVA A;  3NIQ A;  3E6V A;  4ITY A;  4Q3Q A;  4FCI A;  3THE A;  3SL0 A;  4IXU A;  1XFK A;  3SL1 A;  4CEV A;  2PLL A;  5HJ9 A;  1P8O A;  1HQH A;  4Q41 A;  3GN0 A;  1P8Q A;  4Q3V A;  1GQ7 A;  4GWC A;  1TBH A;  1WOH A;  2AEB A;  3E6K A;  4G3H A;  4IE3 A;  2A0M A;  4Q3P A;  3E8Q A;  4HZE A;  1ZPG A;  4IU5 A;  4IU1 A;  4Q3R C;  3RLA A;  1P8M A;  1TBL A;  4RHL A;  4RHK A;  1P8S A;  3TH7 A;  3F80 A;  3MFW A;  4Q3U A;  4IE2 A;  4MXR A;  3THJ A;  1D3V A;  4MYN A;  3THH A;  1P8R A;  2RLA A;  4HXQ A;  4IXV A;  3DJ8 A;  4RHQ A;  1HQ5 A;  1WOG A;  1WVB A;  4RHM A;  4Q3T A;  4Q40 A;  1HQX A;  4RHJ A;  4GSV A;  2EIV A;  4GWD A;  3PZL A;  3NIO A;  1T4T A;  1T4S A;  1WOI A;  3CEV A;  1P8P A;  4Q3S A; 
#chains in the Genus database with same CATH topology
 3MFV A;  3E9B A;  4ZUO A;  2V5W A;  3MJL A;  4I06 A;  2PHA A;  1T4P A;  3LP4 A;  1TBJ A;  4CBY A;  3EZP A;  1RLA A;  1ZPE A;  3MMR A;  3SFH A;  1T69 A;  2EF5 A;  1HQG A;  3M1R A;  4MYL A;  5THS A;  3E8Z A;  2VQQ A;  5EFG A;  1P8N A;  4MYK A;  3F07 A;  4BZ6 A;  2PHO A;  1T4R A;  1C3S A;  1CEV A;  3Q9F A;  3C10 A;  3LHL A;  4FCK A;  1C3P A;  2GH6 A;  2VCG A;  4QA4 A;  4MYF A;  4RLA A;  4ZUN A;  1R1O A;  3LP7 A;  4QA1 A;  3MZ7 A;  5FCW A;  3KV2 A;  3RQD A;  4ZUQ A;  1PQ3 A;  3MEN A;  2VQV A;  3Q9B A;  4HWW A;  3F0R A;  5CEV A;  1C3R A;  4IU4 A;  2VQM A;  5LI3 A;  5RLA A;  5D1C A;  4RN0 A;  1T5G A;  5JI5 A;  2CEV A;  4GSZ A;  5EEM A;  4DZ4 A;  5G0Y A;  1GQ6 A;  5EEI A;  5EFK B;  3F06 A;  1TA1 A;  1HQF A;  4Q3R A;  4RHI A;  5FUE A;  4RN1 A;  5D1D A;  4IE1 A;  5G0H A;  5EEN A;  5G3W A;  3C0Z A;  5G10 A;  3TF3 A;  1T5F A;  3GMZ A;  5G1C A;  3NIP A;  1ZZ0 A;  4Q42 A;  3SKK A;  4GSM A;  3SJT A;  4IU0 A;  2ZAV A;  5G1A A;  3SFF A;  4BZ7 A;  3EW8 A;  2EF4 A;  5EEF A;  1WVA A;  5HJA A;  3EWF A;  3NIQ A;  3E6V A;  4ITY A;  5EFH A;  2VQJ A;  4Q3Q A;  4FCI A;  4QA5 A;  5D1B A;  5EEK A;  4ZUR A;  5THU A;  3THE A;  5G0I A;  5G12 A;  3SL0 A;  4IXU A;  1XFK A;  3SL1 A;  5G17 A;  4LXZ A;  4QA2 A;  3Q9C A;  5G13 A;  5IX0 A;  5DC8 A;  4BZ9 A;  4CBT A;  3MAX A;  4CQF A;  4CEV A;  2PLL A;  2VQO A;  5HJ9 A;  2VQW G;  1P8O A;  5EFN A;  1HQH A;  4Q41 A;  3GN0 A;  1P8Q A;  4Q3V A;  4BZ8 A;  1GQ7 A;  3ZNR A;  5EF7 A;  4A69 A;  1VKG A;  4GWC A;  1TBH A;  1WOH A;  2AEB A;  4QA0 A;  4RN2 A;  3E6K A;  5DC5 A;  4G3H A;  4IE3 A;  4BZ5 A;  1ZZ1 A;  5EFB D;  2A0M A;  4Q3P A;  3E8Q A;  3Q9E A;  4HZE A;  1ZPG A;  4IU5 A;  4IU1 A;  1ZZ3 A;  5G0G A;  5G1B A;  2V5X A;  5THV A;  4Q3R C;  3RLA A;  4ZUP A;  4LY1 A;  1P8M A;  4ZUM A;  1TBL A;  4RHL A;  4RHK A;  1P8S A;  5EFJ D;  3TH7 A;  5EF8 A;  5G0J A;  4QA3 A;  3MZ3 A;  3F80 A;  3MFW A;  4Q3U A;  3MZ6 A;  4BKX B;  4IE2 A;  3MZ4 A;  4MXR A;  3THJ A;  5BWZ A;  3ZNS A;  4QA7 A;  4QA6 A;  1D3V A;  4MYN A;  3C0Y A;  1P8R A;  2RLA A;  3THH A;  5ICN B;  1T67 A;  4HXQ A;  5G0X A;  1T64 A;  3DJ8 A;  4IXV A;  4RHQ A;  5IWG A;  1HQ5 A;  1WOG A;  1WVB A;  3EZT A;  4RHM A;  4Q3T A;  4Q40 A;  5G11 A;  1HQX A;  1W22 A;  4RHJ A;  4GSV A;  2EIV A;  5DC6 A;  4GWD A;  5A2S A;  3PZL A;  3NIO A;  1T4T A;  1T4S A;  1WOI A;  3CEV A;  1P8P A;  5DC7 A;  4Q3S A;  5THT A; 
#chains in the Genus database with same CATH homology
 3MFV A;  3E9B A;  3MJL A;  4I06 A;  2PHA A;  1T4P A;  3LP4 A;  1TBJ A;  1RLA A;  1ZPE A;  3MMR A;  3M1R A;  2EF5 A;  1HQG A;  4MYL A;  3E8Z A;  1P8N A;  4MYK A;  2PHO A;  1T4R A;  1CEV A;  3LHL A;  4FCK A;  4RLA A;  4MYF A;  1R1O A;  3LP7 A;  3KV2 A;  1PQ3 A;  4HWW A;  5CEV A;  4IU4 A;  5RLA A;  1T5G A;  4GSZ A;  2CEV A;  4DZ4 A;  1GQ6 A;  1TA1 A;  1HQF A;  4Q3R A;  4RHI A;  4IE1 A;  3TF3 A;  1T5F A;  3GMZ A;  3NIP A;  4Q42 A;  3SKK A;  4GSM A;  3SJT A;  4IU0 A;  2ZAV A;  2EF4 A;  5HJA A;  1WVA A;  3NIQ A;  3E6V A;  4ITY A;  4Q3Q A;  4FCI A;  3THE A;  3SL0 A;  4IXU A;  1XFK A;  3SL1 A;  4CEV A;  2PLL A;  5HJ9 A;  1P8O A;  1HQH A;  4Q41 A;  3GN0 A;  1P8Q A;  4Q3V A;  1GQ7 A;  4GWC A;  1TBH A;  1WOH A;  2AEB A;  3E6K A;  4G3H A;  4IE3 A;  2A0M A;  4Q3P A;  3E8Q A;  4HZE A;  1ZPG A;  4IU5 A;  4IU1 A;  4Q3R C;  3RLA A;  1P8M A;  1TBL A;  4RHL A;  4RHK A;  1P8S A;  3TH7 A;  3F80 A;  3MFW A;  4Q3U A;  4IE2 A;  4MXR A;  3THJ A;  1D3V A;  4MYN A;  3THH A;  1P8R A;  2RLA A;  4HXQ A;  4IXV A;  3DJ8 A;  4RHQ A;  1HQ5 A;  1WOG A;  1WVB A;  4RHM A;  4Q3T A;  4Q40 A;  1HQX A;  4RHJ A;  4GSV A;  2EIV A;  4GWD A;  3PZL A;  3NIO A;  1T4T A;  1T4S A;  1WOI A;  3CEV A;  1P8P A;  4Q3S A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...