4Q42A

Crystal structure of schistosoma mansoni arginase in complex with l-ornithine
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
345
structure length
336
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Hydrolase
total genus 129
structure length 336
sequence length 345
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q42A00
2EF4A 1TBLA 4CEVA 4RHQA 3E9BA 4Q3RC 2EF5A 4FCIA 4GWCA 3F80A 1GQ7A 1ZPEA 4Q3RA 1PQ3A 4IE2A 4Q3PA 1CEVA 4RHJA 3TH7A 5RLAA 4MYLA 1ZPGA 1P8PA 3THHA 3SL1A 4GWDA 4GSMA 4IU1A 1T4SA 3SL0A 4G3HA 1P8QA 2RLAA 1T5GA 1RLAA 4IU5A 3E6KA 4MXRA 1T4RA 3M1RA 1WVAA 3GN0A 4HWWA 3E8QA 3GMZA 1WOIA 4ITYA 3MMRA 3E8ZA 1D3VA 1P8MA 1P8RA 2PHOA 3DJ8A 4GSVA 1T4TA 2AEBA 4IXVA 1P8SA 3TF3A 1P8OA 1GQ6A 4HXQA 4IE1A 3E6VA 4Q3TA 1HQXA 3NIOA 4Q40A 3RLAA 4IU4A 1HQHA 4GSZA 4RLAA 3SJTA 3KV2A 3LP4A 1T5FA 4MYNA 1XFKA 4RHLA 3THJA 4HZEA 4Q42A 4RHMA 1TA1A 3LP7A 4DZ4A 1TBJA 3PZLA 5HJAA 3LHLA 4IE3A 4MYKA 3THEA 3SKKA 4MYFA 2PLLA 1TBHA 4IU0A 1T4PA 1WOHA 2A0MA 4Q41A 1HQFA 3CEVA 1WOGA 2ZAVA 4RHKA 4Q3SA 2CEVA 2PHAA 3NIPA 1WVBA 5CEVA 3MFVA 3NIQA 4Q3VA 1R1OA 5HJ9A 4RHIA 4I06A 1HQ5A 4FCKA 4Q3QA 2EIVA 3MFWA 3MJLA 1HQGA 1P8NA 4Q3UA 4IXUA
chains in the Genus database with same CATH superfamily
3C10A 4ZURA 2EF4A 4RN0A 1TBLA 4QA2A 5G0YA 4CEVA 4RHQA 3F07A 3E9BA 5EF7A 4Q3RC 5G1AA 2EF5A 4FCIA 4GWCA 3F80A 5THSA 1GQ7A 1ZPEA 1W22A 5EFHA 4QA5A 4Q3RA 1PQ3A 4IE2A 3F0RA 4Q3PA 1CEVA 5G0IA 5IWGA 4RHJA 2V5WA 4BZ8A 3TH7A 5DC5A 5RLAA 4MYLA 1ZPGA 5DC6A 1P8PA 4LXZA 3THHA 2VQVA 5EEIA 3SL1A 4GWDA 3MZ7A 4GSMA 5G10A 5G0GA 4IU1A 1T4SA 3SL0A 4QA4A 5G17A 4G3HA 4ZUQA 1C3RA 4ZUPA 1P8QA 2RLAA 1T5GA 2VQOA 5EEKA 1RLAA 4IU5A 3E6KA 4MXRA 1T4RA 3M1RA 4CBTA 3RQDA 5EFGA 5IX0A 1WVAA 3GN0A 4HWWA 3E8QA 3GMZA 3C0ZA 1WOIA 4ITYA 4RN1A 5THUA 5THVA 3MMRA 3C0YA 3E8ZA 5ICNB 1ZZ1A 1D3VA 1P8MA 4ZUOA 3SFHA 5EFNA 1P8RA 4BZ5A 3MZ4A 4QA3A 2PHOA 1C3PA 3Q9CA 3ZNRA 1T67A 3DJ8A 2VQMA 4GSVA 5G1CA 1T4TA 4BZ6A 2AEBA 1C3SA 5G12A 3EWFA 4A69A 4IXVA 1P8SA 3TF3A 5EFJD 4BZ9A 1P8OA 1GQ6A 1VKGA 4HXQA 4IE1A 3E6VA 4Q3TA 5G13A 1HQXA 3EW8A 3MENA 2VQJA 3NIOA 4Q40A 5G1BA 4IU4A 3RLAA 1HQHA 4GSZA 4RLAA 5LI3A 3SJTA 3KV2A 3LP4A 1T5FA 2VQQA 4MYNA 1XFKA 5THTA 4RHLA 5EEMA 3SFFA 4HZEA 3THJA 5DC8A 4Q42A 4BKXB 3MZ3A 4RHMA 1TA1A 3LP7A 4CQFA 4DZ4A 1TBJA 2VQWG 5EF8A 4ZUNA 3EZTA 3PZLA 5HJAA 4QA7A 3LHLA 4IE3A 4MYKA 2VCGA 4QA1A 3THEA 3SKKA 4MYFA 2PLLA 1TBHA 4IU0A 1T4PA 1WOHA 3Q9EA 2A0MA 4Q41A 1HQFA 1T64A 3CEVA 1WOGA 2ZAVA 3ZNSA 4RHKA 5G11A 4Q3SA 2CEVA 2PHAA 3NIPA 1WVBA 5FCWA 4ZUMA 4BZ7A 5CEVA 5JI5A 5D1DA 4LY1A 2GH6A 5FUEA 5DC7A 3MFVA 3NIQA 1ZZ0A 3MZ6A 5A2SA 4Q3VA 1R1OA 5HJ9A 1ZZ3A 1T69A 4QA6A 4RHIA 5D1CA 4I06A 1HQ5A 3EZPA 4FCKA 5EFBD 5G0JA 4RN2A 5G0XA 5G0HA 4Q3QA 2EIVA 3MFWA 3Q9BA 4CBYA 3MJLA 5BWZA 5EENA 5G3WA 3MAXA 3Q9FA 5D1BA 2V5XA 3F06A 1HQGA 1P8NA 5EFKB 4QA0A 5EEFA 4Q3UA 4IXUA
chains in the Genus database with same CATH topology
2EF4A 1TBLA 4CEVA 4RHQA 3E9BA 4Q3RC 2EF5A 4FCIA 4GWCA 3F80A 1GQ7A 1ZPEA 4Q3RA 1PQ3A 4IE2A 4Q3PA 1CEVA 4RHJA 3TH7A 5RLAA 4MYLA 1ZPGA 1P8PA 3THHA 3SL1A 4GWDA 4GSMA 4IU1A 1T4SA 3SL0A 4G3HA 1P8QA 2RLAA 1T5GA 1RLAA 4IU5A 3E6KA 4MXRA 1T4RA 3M1RA 1WVAA 3GN0A 4HWWA 3E8QA 3GMZA 1WOIA 4ITYA 3MMRA 3E8ZA 1D3VA 1P8MA 1P8RA 2PHOA 3DJ8A 4GSVA 1T4TA 2AEBA 4IXVA 1P8SA 3TF3A 1P8OA 1GQ6A 4HXQA 4IE1A 3E6VA 4Q3TA 1HQXA 3NIOA 4Q40A 3RLAA 4IU4A 1HQHA 4GSZA 4RLAA 3SJTA 3KV2A 3LP4A 1T5FA 4MYNA 1XFKA 4RHLA 3THJA 4HZEA 4Q42A 4RHMA 1TA1A 3LP7A 4DZ4A 1TBJA 3PZLA 5HJAA 3LHLA 4IE3A 4MYKA 3THEA 3SKKA 4MYFA 2PLLA 1TBHA 4IU0A 1T4PA 1WOHA 2A0MA 4Q41A 1HQFA 3CEVA 1WOGA 2ZAVA 4RHKA 4Q3SA 2CEVA 2PHAA 3NIPA 1WVBA 5CEVA 3MFVA 3NIQA 4Q3VA 1R1OA 5HJ9A 4RHIA 4I06A 1HQ5A 4FCKA 4Q3QA 2EIVA 3MFWA 3MJLA 1HQGA 1P8NA 4Q3UA 4IXUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EF4 A;  1TBL A;  4CEV A;  4RHQ A;  3E9B A;  4Q3R C;  2EF5 A;  4FCI A;  4GWC A;  3F80 A;  1GQ7 A;  1ZPE A;  4Q3R A;  1PQ3 A;  4IE2 A;  4Q3P A;  1CEV A;  4RHJ A;  3TH7 A;  5RLA A;  4MYL A;  1ZPG A;  1P8P A;  3THH A;  3SL1 A;  4GWD A;  4GSM A;  4IU1 A;  1T4S A;  3SL0 A;  4G3H A;  1P8Q A;  2RLA A;  1T5G A;  1RLA A;  4IU5 A;  3E6K A;  4MXR A;  1T4R A;  3M1R A;  1WVA A;  3GN0 A;  4HWW A;  3E8Q A;  3GMZ A;  1WOI A;  4ITY A;  3MMR A;  3E8Z A;  1D3V A;  1P8M A;  1P8R A;  2PHO A;  3DJ8 A;  4GSV A;  1T4T A;  2AEB A;  4IXV A;  1P8S A;  3TF3 A;  1P8O A;  1GQ6 A;  4HXQ A;  4IE1 A;  3E6V A;  4Q3T A;  1HQX A;  3NIO A;  4Q40 A;  3RLA A;  4IU4 A;  1HQH A;  4GSZ A;  4RLA A;  3SJT A;  3KV2 A;  3LP4 A;  1T5F A;  4MYN A;  1XFK A;  4RHL A;  3THJ A;  4HZE A;  4Q42 A;  4RHM A;  1TA1 A;  3LP7 A;  4DZ4 A;  1TBJ A;  3PZL A;  5HJA A;  3LHL A;  4IE3 A;  4MYK A;  3THE A;  3SKK A;  4MYF A;  2PLL A;  1TBH A;  4IU0 A;  1T4P A;  1WOH A;  2A0M A;  4Q41 A;  1HQF A;  3CEV A;  1WOG A;  2ZAV A;  4RHK A;  4Q3S A;  2CEV A;  2PHA A;  3NIP A;  1WVB A;  5CEV A;  3MFV A;  3NIQ A;  4Q3V A;  1R1O A;  5HJ9 A;  4RHI A;  4I06 A;  1HQ5 A;  4FCK A;  4Q3Q A;  2EIV A;  3MFW A;  3MJL A;  1HQG A;  1P8N A;  4Q3U A;  4IXU A; 
#chains in the Genus database with same CATH topology
 3C10 A;  4ZUR A;  2EF4 A;  4RN0 A;  1TBL A;  4QA2 A;  5G0Y A;  4CEV A;  4RHQ A;  3F07 A;  3E9B A;  5EF7 A;  4Q3R C;  5G1A A;  2EF5 A;  4FCI A;  4GWC A;  3F80 A;  5THS A;  1GQ7 A;  1ZPE A;  1W22 A;  5EFH A;  4QA5 A;  4Q3R A;  1PQ3 A;  4IE2 A;  3F0R A;  4Q3P A;  1CEV A;  5G0I A;  5IWG A;  4RHJ A;  2V5W A;  4BZ8 A;  3TH7 A;  5DC5 A;  5RLA A;  4MYL A;  1ZPG A;  5DC6 A;  1P8P A;  4LXZ A;  3THH A;  2VQV A;  5EEI A;  3SL1 A;  4GWD A;  3MZ7 A;  4GSM A;  5G10 A;  5G0G A;  4IU1 A;  1T4S A;  3SL0 A;  4QA4 A;  5G17 A;  4G3H A;  4ZUQ A;  1C3R A;  4ZUP A;  1P8Q A;  2RLA A;  1T5G A;  2VQO A;  5EEK A;  1RLA A;  4IU5 A;  3E6K A;  4MXR A;  1T4R A;  3M1R A;  4CBT A;  3RQD A;  5EFG A;  5IX0 A;  1WVA A;  3GN0 A;  4HWW A;  3E8Q A;  3GMZ A;  3C0Z A;  1WOI A;  4ITY A;  4RN1 A;  5THU A;  5THV A;  3MMR A;  3C0Y A;  3E8Z A;  5ICN B;  1ZZ1 A;  1D3V A;  1P8M A;  4ZUO A;  3SFH A;  5EFN A;  1P8R A;  4BZ5 A;  3MZ4 A;  4QA3 A;  2PHO A;  1C3P A;  3Q9C A;  3ZNR A;  1T67 A;  3DJ8 A;  2VQM A;  4GSV A;  5G1C A;  1T4T A;  4BZ6 A;  2AEB A;  1C3S A;  5G12 A;  3EWF A;  4A69 A;  4IXV A;  1P8S A;  3TF3 A;  5EFJ D;  4BZ9 A;  1P8O A;  1GQ6 A;  1VKG A;  4HXQ A;  4IE1 A;  3E6V A;  4Q3T A;  5G13 A;  1HQX A;  3EW8 A;  3MEN A;  2VQJ A;  3NIO A;  4Q40 A;  5G1B A;  4IU4 A;  3RLA A;  1HQH A;  4GSZ A;  4RLA A;  5LI3 A;  3SJT A;  3KV2 A;  3LP4 A;  1T5F A;  2VQQ A;  4MYN A;  1XFK A;  5THT A;  4RHL A;  5EEM A;  3SFF A;  4HZE A;  3THJ A;  5DC8 A;  4Q42 A;  4BKX B;  3MZ3 A;  4RHM A;  1TA1 A;  3LP7 A;  4CQF A;  4DZ4 A;  1TBJ A;  2VQW G;  5EF8 A;  4ZUN A;  3EZT A;  3PZL A;  5HJA A;  4QA7 A;  3LHL A;  4IE3 A;  4MYK A;  2VCG A;  4QA1 A;  3THE A;  3SKK A;  4MYF A;  2PLL A;  1TBH A;  4IU0 A;  1T4P A;  1WOH A;  3Q9E A;  2A0M A;  4Q41 A;  1HQF A;  1T64 A;  3CEV A;  1WOG A;  2ZAV A;  3ZNS A;  4RHK A;  5G11 A;  4Q3S A;  2CEV A;  2PHA A;  3NIP A;  1WVB A;  5FCW A;  4ZUM A;  4BZ7 A;  5CEV A;  5JI5 A;  5D1D A;  4LY1 A;  2GH6 A;  5FUE A;  5DC7 A;  3MFV A;  3NIQ A;  1ZZ0 A;  3MZ6 A;  5A2S A;  4Q3V A;  1R1O A;  5HJ9 A;  1ZZ3 A;  1T69 A;  4QA6 A;  4RHI A;  5D1C A;  4I06 A;  1HQ5 A;  3EZP A;  4FCK A;  5EFB D;  5G0J A;  4RN2 A;  5G0X A;  5G0H A;  4Q3Q A;  2EIV A;  3MFW A;  3Q9B A;  4CBY A;  3MJL A;  5BWZ A;  5EEN A;  5G3W A;  3MAX A;  3Q9F A;  5D1B A;  2V5X A;  3F06 A;  1HQG A;  1P8N A;  5EFK B;  4QA0 A;  5EEF A;  4Q3U A;  4IXU A; 
#chains in the Genus database with same CATH homology
 2EF4 A;  1TBL A;  4CEV A;  4RHQ A;  3E9B A;  4Q3R C;  2EF5 A;  4FCI A;  4GWC A;  3F80 A;  1GQ7 A;  1ZPE A;  4Q3R A;  1PQ3 A;  4IE2 A;  4Q3P A;  1CEV A;  4RHJ A;  3TH7 A;  5RLA A;  4MYL A;  1ZPG A;  1P8P A;  3THH A;  3SL1 A;  4GWD A;  4GSM A;  4IU1 A;  1T4S A;  3SL0 A;  4G3H A;  1P8Q A;  2RLA A;  1T5G A;  1RLA A;  4IU5 A;  3E6K A;  4MXR A;  1T4R A;  3M1R A;  1WVA A;  3GN0 A;  4HWW A;  3E8Q A;  3GMZ A;  1WOI A;  4ITY A;  3MMR A;  3E8Z A;  1D3V A;  1P8M A;  1P8R A;  2PHO A;  3DJ8 A;  4GSV A;  1T4T A;  2AEB A;  4IXV A;  1P8S A;  3TF3 A;  1P8O A;  1GQ6 A;  4HXQ A;  4IE1 A;  3E6V A;  4Q3T A;  1HQX A;  3NIO A;  4Q40 A;  3RLA A;  4IU4 A;  1HQH A;  4GSZ A;  4RLA A;  3SJT A;  3KV2 A;  3LP4 A;  1T5F A;  4MYN A;  1XFK A;  4RHL A;  3THJ A;  4HZE A;  4Q42 A;  4RHM A;  1TA1 A;  3LP7 A;  4DZ4 A;  1TBJ A;  3PZL A;  5HJA A;  3LHL A;  4IE3 A;  4MYK A;  3THE A;  3SKK A;  4MYF A;  2PLL A;  1TBH A;  4IU0 A;  1T4P A;  1WOH A;  2A0M A;  4Q41 A;  1HQF A;  3CEV A;  1WOG A;  2ZAV A;  4RHK A;  4Q3S A;  2CEV A;  2PHA A;  3NIP A;  1WVB A;  5CEV A;  3MFV A;  3NIQ A;  4Q3V A;  1R1O A;  5HJ9 A;  4RHI A;  4I06 A;  1HQ5 A;  4FCK A;  4Q3Q A;  2EIV A;  3MFW A;  3MJL A;  1HQG A;  1P8N A;  4Q3U A;  4IXU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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