3SL1A

Crystal structure of p. falciparum arginase complexed with 2-amino-6-borono-2-methylhexanoic acid
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
390
structure length
308
Chain Sequence
b'KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSENLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
pubmed doi rcsb
source organism Plasmodium falciparum
molecule tags Hydrolase/hydrolase inhibitor
total genus 119
structure length 308
sequence length 390
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2011-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3sl1A00
4IU4A 1T5GA 1P8PA 1P8SA 3MMRA 4GWDA 3TF3A 4GSVA 1PQ3A 3E8QA 4GSMA 4Q3PA 4Q3SA 3NIPA 3SJTA 4FCIA 4Q3VA 4Q3RA 5HJAA 3MFVA 4Q3UA 1ZPGA 1P8MA 3THHA 4HXQA 1P8RA 4Q41A 1HQFA 3GMZA 4RLAA 3KV2A 1D3VA 4IU0A 1P8NA 3DJ8A 3NIOA 3F80A 1TBHA 2RLAA 4Q42A 2PLLA 1HQXA 1P8OA 1TBJA 3E6VA 2EF5A 1T5FA 1P8QA 2EIVA 4ITYA 1T4TA 3SL1A 1T4RA 5CEVA 2PHOA 2ZAVA 1RLAA 4IXUA 4Q3QA 2PHAA 3RLAA 1T4SA 3THEA 1XFKA 3M1RA 4IE3A 3SL0A 4G3HA 3NIQA 3TH7A 1WOGA 3LP7A 4RHIA 4IXVA 3GN0A 4I06A 1WOIA 3SKKA 1T4PA 1TBLA 1GQ6A 1WOHA 1ZPEA 1TA1A 2CEVA 5HJ9A 1CEVA 4MYLA 1HQ5A 2AEBA 4MYFA 1R1OA 3MJLA 2EF4A 2A0MA 4Q40A 1GQ7A 4MYKA 4GSZA 4Q3TA 4IE1A 4DZ4A 4HZEA 4IU1A 3THJA 3CEVA 3MFWA 1HQGA 1WVBA 3E9BA 3E6KA 3PZLA 4HWWA 3E8ZA 4Q3RC 4CEVA 4FCKA 4MXRA 4RHJA 4RHQA 3LP4A 4MYNA 1HQHA 4IE2A 4IU5A 3LHLA 4RHLA 5RLAA 4RHKA 4RHMA 1WVAA 4GWCA
chains in the Genus database with same CATH superfamily
4IU4A 1T5GA 5EFBD 5THSA 3ZNSA 1P8PA 4RN2A 1P8SA 3MMRA 4GWDA 5DC5A 5G0YA 5G17A 3EZTA 4GSVA 4LY1A 3F0RA 1PQ3A 3TF3A 4BZ9A 4CBTA 3Q9EA 3E8QA 5A2SA 4GSMA 4Q3PA 4QA0A 5D1BA 3SFFA 5G0GA 4Q3SA 3MZ3A 5EFKB 3NIPA 3C10A 3SJTA 4FCIA 5D1DA 4Q3VA 4Q3RA 5HJAA 5DC6A 4QA2A 3MFVA 4Q3UA 1ZPGA 5G11A 4BZ5A 1P8MA 5BWZA 5JI5A 5G13A 3THHA 4HXQA 1P8RA 4ZUMA 2VCGA 4LXZA 4Q41A 1HQFA 1VKGA 3GMZA 4RLAA 3KV2A 1D3VA 4IU0A 1C3SA 5G1BA 1P8NA 3EZPA 5G12A 2VQWG 3DJ8A 4ZUQA 3NIOA 3SFHA 3F80A 1TBHA 2RLAA 4Q42A 4BKXB 2PLLA 1HQXA 1P8OA 1TBJA 3E6VA 2EF5A 1W22A 5EFNA 1T5FA 5IX0A 2VQJA 3Q9FA 5DC8A 1P8QA 1T67A 2EIVA 4QA7A 4ITYA 5EEMA 1T4TA 4BZ6A 5G0JA 3SL1A 1T4RA 4QA5A 5CEVA 2PHOA 5G10A 2ZAVA 1RLAA 3F07A 3MZ4A 4IXUA 4Q3QA 5THVA 2PHAA 3RLAA 5FCWA 4QA4A 1ZZ3A 5G0IA 1T4SA 3EWFA 5IWGA 3ZNRA 4BZ8A 3THEA 1XFKA 2GH6A 4QA3A 3M1RA 4IE3A 3SL0A 4G3HA 3NIQA 3TH7A 1WOGA 3LP7A 4RHIA 4IXVA 5EF7A 3GN0A 2V5XA 4I06A 4BZ7A 1WOIA 3MZ7A 4CQFA 3SKKA 3C0YA 1T4PA 1T69A 1TBLA 1GQ6A 1WOHA 5EEFA 1ZPEA 1TA1A 2CEVA 5THUA 5HJ9A 1CEVA 4MYLA 5THTA 1HQ5A 2AEBA 1C3PA 5EF8A 2V5WA 4MYFA 1R1OA 3F06A 3MJLA 2EF4A 1T64A 3Q9CA 2A0MA 4Q40A 3Q9BA 4QA6A 5G0HA 3RQDA 5ICNB 5EEKA 1GQ7A 2VQMA 4MYKA 2VQOA 5EENA 4GSZA 4Q3TA 4ZURA 4IE1A 5G0XA 4DZ4A 3C0ZA 4HZEA 1ZZ1A 4IU1A 5EFGA 5LI3A 5G1CA 5D1CA 3CEVA 3THJA 3MFWA 5EFJD 1HQGA 3MENA 1WVBA 3MAXA 3E9BA 4CBYA 3EW8A 4ZUNA 3E6KA 3PZLA 4HWWA 3E8ZA 3MZ6A 4Q3RC 5EFHA 4CEVA 4FCKA 4MXRA 5G1AA 1ZZ0A 4A69A 5EEIA 4RHJA 1C3RA 4RHQA 3LP4A 5FUEA 4ZUOA 2VQQA 4MYNA 1HQHA 4IE2A 4RN1A 5DC7A 4IU5A 3LHLA 4RHLA 5RLAA 4QA1A 4ZUPA 4RHKA 4RN0A 4RHMA 1WVAA 2VQVA 5G3WA 4GWCA
chains in the Genus database with same CATH topology
4IU4A 1T5GA 1P8PA 1P8SA 3MMRA 4GWDA 3TF3A 4GSVA 1PQ3A 3E8QA 4GSMA 4Q3PA 4Q3SA 3NIPA 3SJTA 4FCIA 4Q3VA 4Q3RA 5HJAA 3MFVA 4Q3UA 1ZPGA 1P8MA 3THHA 4HXQA 1P8RA 4Q41A 1HQFA 3GMZA 4RLAA 3KV2A 1D3VA 4IU0A 1P8NA 3DJ8A 3NIOA 3F80A 1TBHA 2RLAA 4Q42A 2PLLA 1HQXA 1P8OA 1TBJA 3E6VA 2EF5A 1T5FA 1P8QA 2EIVA 4ITYA 1T4TA 3SL1A 1T4RA 5CEVA 2PHOA 2ZAVA 1RLAA 4IXUA 4Q3QA 2PHAA 3RLAA 1T4SA 3THEA 1XFKA 3M1RA 4IE3A 3SL0A 4G3HA 3NIQA 3TH7A 1WOGA 3LP7A 4RHIA 4IXVA 3GN0A 4I06A 1WOIA 3SKKA 1T4PA 1TBLA 1GQ6A 1WOHA 1ZPEA 1TA1A 2CEVA 5HJ9A 1CEVA 4MYLA 1HQ5A 2AEBA 4MYFA 1R1OA 3MJLA 2EF4A 2A0MA 4Q40A 1GQ7A 4MYKA 4GSZA 4Q3TA 4IE1A 4DZ4A 4HZEA 4IU1A 3THJA 3CEVA 3MFWA 1HQGA 1WVBA 3E9BA 3E6KA 3PZLA 4HWWA 3E8ZA 4Q3RC 4CEVA 4FCKA 4MXRA 4RHJA 4RHQA 3LP4A 4MYNA 1HQHA 4IE2A 4IU5A 3LHLA 4RHLA 5RLAA 4RHKA 4RHMA 1WVAA 4GWCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IU4 A;  1T5G A;  1P8P A;  1P8S A;  3MMR A;  4GWD A;  3TF3 A;  4GSV A;  1PQ3 A;  3E8Q A;  4GSM A;  4Q3P A;  4Q3S A;  3NIP A;  3SJT A;  4FCI A;  4Q3V A;  4Q3R A;  5HJA A;  3MFV A;  4Q3U A;  1ZPG A;  1P8M A;  3THH A;  4HXQ A;  1P8R A;  4Q41 A;  1HQF A;  3GMZ A;  4RLA A;  3KV2 A;  1D3V A;  4IU0 A;  1P8N A;  3DJ8 A;  3NIO A;  3F80 A;  1TBH A;  2RLA A;  4Q42 A;  2PLL A;  1HQX A;  1P8O A;  1TBJ A;  3E6V A;  2EF5 A;  1T5F A;  1P8Q A;  2EIV A;  4ITY A;  1T4T A;  3SL1 A;  1T4R A;  5CEV A;  2PHO A;  2ZAV A;  1RLA A;  4IXU A;  4Q3Q A;  2PHA A;  3RLA A;  1T4S A;  3THE A;  1XFK A;  3M1R A;  4IE3 A;  3SL0 A;  4G3H A;  3NIQ A;  3TH7 A;  1WOG A;  3LP7 A;  4RHI A;  4IXV A;  3GN0 A;  4I06 A;  1WOI A;  3SKK A;  1T4P A;  1TBL A;  1GQ6 A;  1WOH A;  1ZPE A;  1TA1 A;  2CEV A;  5HJ9 A;  1CEV A;  4MYL A;  1HQ5 A;  2AEB A;  4MYF A;  1R1O A;  3MJL A;  2EF4 A;  2A0M A;  4Q40 A;  1GQ7 A;  4MYK A;  4GSZ A;  4Q3T A;  4IE1 A;  4DZ4 A;  4HZE A;  4IU1 A;  3THJ A;  3CEV A;  3MFW A;  1HQG A;  1WVB A;  3E9B A;  3E6K A;  3PZL A;  4HWW A;  3E8Z A;  4Q3R C;  4CEV A;  4FCK A;  4MXR A;  4RHJ A;  4RHQ A;  3LP4 A;  4MYN A;  1HQH A;  4IE2 A;  4IU5 A;  3LHL A;  4RHL A;  5RLA A;  4RHK A;  4RHM A;  1WVA A;  4GWC A; 
#chains in the Genus database with same CATH topology
 4IU4 A;  1T5G A;  5EFB D;  5THS A;  3ZNS A;  1P8P A;  4RN2 A;  1P8S A;  3MMR A;  4GWD A;  5DC5 A;  5G0Y A;  5G17 A;  3EZT A;  4GSV A;  4LY1 A;  3F0R A;  1PQ3 A;  3TF3 A;  4BZ9 A;  4CBT A;  3Q9E A;  3E8Q A;  5A2S A;  4GSM A;  4Q3P A;  4QA0 A;  5D1B A;  3SFF A;  5G0G A;  4Q3S A;  3MZ3 A;  5EFK B;  3NIP A;  3C10 A;  3SJT A;  4FCI A;  5D1D A;  4Q3V A;  4Q3R A;  5HJA A;  5DC6 A;  4QA2 A;  3MFV A;  4Q3U A;  1ZPG A;  5G11 A;  4BZ5 A;  1P8M A;  5BWZ A;  5JI5 A;  5G13 A;  3THH A;  4HXQ A;  1P8R A;  4ZUM A;  2VCG A;  4LXZ A;  4Q41 A;  1HQF A;  1VKG A;  3GMZ A;  4RLA A;  3KV2 A;  1D3V A;  4IU0 A;  1C3S A;  5G1B A;  1P8N A;  3EZP A;  5G12 A;  2VQW G;  3DJ8 A;  4ZUQ A;  3NIO A;  3SFH A;  3F80 A;  1TBH A;  2RLA A;  4Q42 A;  4BKX B;  2PLL A;  1HQX A;  1P8O A;  1TBJ A;  3E6V A;  2EF5 A;  1W22 A;  5EFN A;  1T5F A;  5IX0 A;  2VQJ A;  3Q9F A;  5DC8 A;  1P8Q A;  1T67 A;  2EIV A;  4QA7 A;  4ITY A;  5EEM A;  1T4T A;  4BZ6 A;  5G0J A;  3SL1 A;  1T4R A;  4QA5 A;  5CEV A;  2PHO A;  5G10 A;  2ZAV A;  1RLA A;  3F07 A;  3MZ4 A;  4IXU A;  4Q3Q A;  5THV A;  2PHA A;  3RLA A;  5FCW A;  4QA4 A;  1ZZ3 A;  5G0I A;  1T4S A;  3EWF A;  5IWG A;  3ZNR A;  4BZ8 A;  3THE A;  1XFK A;  2GH6 A;  4QA3 A;  3M1R A;  4IE3 A;  3SL0 A;  4G3H A;  3NIQ A;  3TH7 A;  1WOG A;  3LP7 A;  4RHI A;  4IXV A;  5EF7 A;  3GN0 A;  2V5X A;  4I06 A;  4BZ7 A;  1WOI A;  3MZ7 A;  4CQF A;  3SKK A;  3C0Y A;  1T4P A;  1T69 A;  1TBL A;  1GQ6 A;  1WOH A;  5EEF A;  1ZPE A;  1TA1 A;  2CEV A;  5THU A;  5HJ9 A;  1CEV A;  4MYL A;  5THT A;  1HQ5 A;  2AEB A;  1C3P A;  5EF8 A;  2V5W A;  4MYF A;  1R1O A;  3F06 A;  3MJL A;  2EF4 A;  1T64 A;  3Q9C A;  2A0M A;  4Q40 A;  3Q9B A;  4QA6 A;  5G0H A;  3RQD A;  5ICN B;  5EEK A;  1GQ7 A;  2VQM A;  4MYK A;  2VQO A;  5EEN A;  4GSZ A;  4Q3T A;  4ZUR A;  4IE1 A;  5G0X A;  4DZ4 A;  3C0Z A;  4HZE A;  1ZZ1 A;  4IU1 A;  5EFG A;  5LI3 A;  5G1C A;  5D1C A;  3CEV A;  3THJ A;  3MFW A;  5EFJ D;  1HQG A;  3MEN A;  1WVB A;  3MAX A;  3E9B A;  4CBY A;  3EW8 A;  4ZUN A;  3E6K A;  3PZL A;  4HWW A;  3E8Z A;  3MZ6 A;  4Q3R C;  5EFH A;  4CEV A;  4FCK A;  4MXR A;  5G1A A;  1ZZ0 A;  4A69 A;  5EEI A;  4RHJ A;  1C3R A;  4RHQ A;  3LP4 A;  5FUE A;  4ZUO A;  2VQQ A;  4MYN A;  1HQH A;  4IE2 A;  4RN1 A;  5DC7 A;  4IU5 A;  3LHL A;  4RHL A;  5RLA A;  4QA1 A;  4ZUP A;  4RHK A;  4RN0 A;  4RHM A;  1WVA A;  2VQV A;  5G3W A;  4GWC A; 
#chains in the Genus database with same CATH homology
 4IU4 A;  1T5G A;  1P8P A;  1P8S A;  3MMR A;  4GWD A;  3TF3 A;  4GSV A;  1PQ3 A;  3E8Q A;  4GSM A;  4Q3P A;  4Q3S A;  3NIP A;  3SJT A;  4FCI A;  4Q3V A;  4Q3R A;  5HJA A;  3MFV A;  4Q3U A;  1ZPG A;  1P8M A;  3THH A;  4HXQ A;  1P8R A;  4Q41 A;  1HQF A;  3GMZ A;  4RLA A;  3KV2 A;  1D3V A;  4IU0 A;  1P8N A;  3DJ8 A;  3NIO A;  3F80 A;  1TBH A;  2RLA A;  4Q42 A;  2PLL A;  1HQX A;  1P8O A;  1TBJ A;  3E6V A;  2EF5 A;  1T5F A;  1P8Q A;  2EIV A;  4ITY A;  1T4T A;  3SL1 A;  1T4R A;  5CEV A;  2PHO A;  2ZAV A;  1RLA A;  4IXU A;  4Q3Q A;  2PHA A;  3RLA A;  1T4S A;  3THE A;  1XFK A;  3M1R A;  4IE3 A;  3SL0 A;  4G3H A;  3NIQ A;  3TH7 A;  1WOG A;  3LP7 A;  4RHI A;  4IXV A;  3GN0 A;  4I06 A;  1WOI A;  3SKK A;  1T4P A;  1TBL A;  1GQ6 A;  1WOH A;  1ZPE A;  1TA1 A;  2CEV A;  5HJ9 A;  1CEV A;  4MYL A;  1HQ5 A;  2AEB A;  4MYF A;  1R1O A;  3MJL A;  2EF4 A;  2A0M A;  4Q40 A;  1GQ7 A;  4MYK A;  4GSZ A;  4Q3T A;  4IE1 A;  4DZ4 A;  4HZE A;  4IU1 A;  3THJ A;  3CEV A;  3MFW A;  1HQG A;  1WVB A;  3E9B A;  3E6K A;  3PZL A;  4HWW A;  3E8Z A;  4Q3R C;  4CEV A;  4FCK A;  4MXR A;  4RHJ A;  4RHQ A;  3LP4 A;  4MYN A;  1HQH A;  4IE2 A;  4IU5 A;  3LHL A;  4RHL A;  5RLA A;  4RHK A;  4RHM A;  1WVA A;  4GWC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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