1HQGA

Crystal structure of the h141c arginase variant complexed with products ornithine and urea
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
314
structure length
313
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords ARGINASE 1
total genus 113
structure length 313
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2000-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1hqgA00
4RHQA 4IE3A 3THEA 1GQ7A 4HXQA 4IE1A 3TH7A 4MYNA 3LP7A 5HJ9A 5HJAA 1PQ3A 4GSMA 2AEBA 1GQ6A 1R1OA 4IU1A 3E8ZA 4IU5A 4MYFA 4RLAA 4Q3RA 1HQXA 3SKKA 4GWCA 4IU0A 4I06A 1WVAA 1P8PA 3MFWA 4G3HA 3GN0A 2PLLA 1TBLA 1HQ5A 1WVBA 2PHOA 1CEVA 4HWWA 1WOIA 3MMRA 3RLAA 4IXUA 4DZ4A 1T4PA 2PHAA 1T5FA 1T4TA 1XFKA 4CEVA 5RLAA 1P8QA 3GMZA 3SJTA 3NIPA 4GSZA 4Q41A 1ZPGA 4MXRA 2CEVA 1P8OA 2EIVA 3THHA 1TA1A 1P8NA 2A0MA 1WOGA 4RHMA 4IXVA 4Q3SA 1T4RA 4ITYA 2ZAVA 3NIOA 4GSVA 4IE2A 4Q3UA 1P8SA 4FCKA 4Q3RC 3KV2A 2EF5A 4RHIA 3F80A 2EF4A 3NIQA 4IU4A 3TF3A 4RHJA 5CEVA 1P8RA 1HQGA 4Q42A 3LHLA 1T4SA 4GWDA 4RHKA 1ZPEA 1P8MA 1WOHA 4Q3TA 1HQHA 4Q40A 2RLAA 3M1RA 4HZEA 1HQFA 3SL1A 3CEVA 4Q3VA 4MYLA 3E9BA 3MFVA 1TBJA 3MJLA 3DJ8A 4MYKA 4Q3QA 4Q3PA 1T5GA 3E6VA 4RHLA 1TBHA 1D3VA 3E6KA 1RLAA 3LP4A 4FCIA 3SL0A 3E8QA 3PZLA 3THJA
chains in the Genus database with same CATH superfamily
1C3PA 1T69A 4RHQA 4BKXB 4BZ5A 3C10A 4IE3A 3THEA 1GQ7A 2V5XA 1T64A 3EWFA 4CQFA 4HXQA 1W22A 3SFHA 4IE1A 5EFHA 3TH7A 4MYNA 5DC6A 3LP7A 5HJ9A 5EFJD 5HJAA 3F06A 1PQ3A 4GSMA 2AEBA 1GQ6A 1R1OA 4IU1A 3E8ZA 3EW8A 4IU5A 4MYFA 3C0ZA 4RLAA 3F07A 4RN0A 4Q3RA 5DC8A 1HQXA 5G17A 5G0YA 3SKKA 5EEIA 4GWCA 4IU0A 4I06A 1WVAA 5DC7A 1P8PA 3MFWA 2VQVA 4G3HA 4QA6A 3GN0A 2PLLA 1TBLA 4CBTA 5ICNB 4RN1A 1HQ5A 1WVBA 2PHOA 4A69A 2V5WA 3SFFA 1CEVA 4HWWA 1WOIA 2VQOA 3MMRA 4ZUNA 3RLAA 4ZUQA 3Q9BA 4IXUA 4DZ4A 5G0IA 4LY1A 1T4PA 2PHAA 5G3WA 1T5FA 1T4TA 3EZTA 1XFKA 4ZUPA 4CEVA 5RLAA 5EEFA 5G0JA 1P8QA 3EZPA 3GMZA 3MZ3A 2VQWG 3NIPA 3SJTA 5EFKB 5EFNA 4GSZA 5D1CA 5FCWA 4Q41A 1ZPGA 2VQQA 5D1BA 5FUEA 4MXRA 2CEVA 1P8OA 3MZ7A 2EIVA 3THHA 1TA1A 1P8NA 2A0MA 3Q9FA 1WOGA 4RHMA 5A2SA 4IXVA 4Q3SA 2VQMA 1T4RA 4QA1A 4ITYA 5IX0A 4ZUMA 1C3SA 3MZ4A 2ZAVA 3NIOA 4GSVA 4IE2A 5EF7A 5D1DA 4CBYA 4Q3UA 5THVA 1P8SA 4FCKA 4Q3RC 3KV2A 4QA3A 5EEKA 5THUA 3MZ6A 5G11A 5G1AA 3F0RA 2VQJA 2EF5A 4RHIA 5THSA 3Q9CA 3F80A 5G1CA 4LXZA 5LI3A 5EENA 1C3RA 2EF4A 3NIQA 4QA0A 3MAXA 1T67A 4IU4A 3TF3A 4RHJA 3ZNSA 3C0YA 1P8RA 5CEVA 1HQGA 4QA4A 3RQDA 3Q9EA 5G0XA 5JI5A 5DC5A 4Q42A 4BZ6A 3LHLA 1T4SA 5G13A 5IWGA 4GWDA 5G12A 5EEMA 4RHKA 4QA5A 1ZPEA 1P8MA 1WOHA 4BZ7A 1ZZ1A 3ZNRA 4BZ9A 5G0HA 4ZUOA 4BZ8A 4QA7A 4RN2A 3MENA 4Q3TA 1HQHA 4Q40A 2RLAA 3M1RA 4HZEA 5G0GA 4QA2A 1HQFA 2GH6A 3SL1A 5EFGA 3CEVA 4Q3VA 4MYLA 3E9BA 3MFVA 1TBJA 5EF8A 5EFBD 1ZZ0A 5BWZA 3MJLA 3DJ8A 4MYKA 4Q3QA 4Q3PA 1T5GA 3E6VA 4RHLA 1ZZ3A 2VCGA 1TBHA 1D3VA 3E6KA 1RLAA 1VKGA 3LP4A 4FCIA 5G10A 5THTA 3E8QA 3SL0A 4ZURA 5G1BA 3PZLA 3THJA
chains in the Genus database with same CATH topology
4RHQA 4IE3A 3THEA 1GQ7A 4HXQA 4IE1A 3TH7A 4MYNA 3LP7A 5HJ9A 5HJAA 1PQ3A 4GSMA 2AEBA 1GQ6A 1R1OA 4IU1A 3E8ZA 4IU5A 4MYFA 4RLAA 4Q3RA 1HQXA 3SKKA 4GWCA 4IU0A 4I06A 1WVAA 1P8PA 3MFWA 4G3HA 3GN0A 2PLLA 1TBLA 1HQ5A 1WVBA 2PHOA 1CEVA 4HWWA 1WOIA 3MMRA 3RLAA 4IXUA 4DZ4A 1T4PA 2PHAA 1T5FA 1T4TA 1XFKA 4CEVA 5RLAA 1P8QA 3GMZA 3SJTA 3NIPA 4GSZA 4Q41A 1ZPGA 4MXRA 2CEVA 1P8OA 2EIVA 3THHA 1TA1A 1P8NA 2A0MA 1WOGA 4RHMA 4IXVA 4Q3SA 1T4RA 4ITYA 2ZAVA 3NIOA 4GSVA 4IE2A 4Q3UA 1P8SA 4FCKA 4Q3RC 3KV2A 2EF5A 4RHIA 3F80A 2EF4A 3NIQA 4IU4A 3TF3A 4RHJA 5CEVA 1P8RA 1HQGA 4Q42A 3LHLA 1T4SA 4GWDA 4RHKA 1ZPEA 1P8MA 1WOHA 4Q3TA 1HQHA 4Q40A 2RLAA 3M1RA 4HZEA 1HQFA 3SL1A 3CEVA 4Q3VA 4MYLA 3E9BA 3MFVA 1TBJA 3MJLA 3DJ8A 4MYKA 4Q3QA 4Q3PA 1T5GA 3E6VA 4RHLA 1TBHA 1D3VA 3E6KA 1RLAA 3LP4A 4FCIA 3SL0A 3E8QA 3PZLA 3THJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RHQ A;  4IE3 A;  3THE A;  1GQ7 A;  4HXQ A;  4IE1 A;  3TH7 A;  4MYN A;  3LP7 A;  5HJ9 A;  5HJA A;  1PQ3 A;  4GSM A;  2AEB A;  1GQ6 A;  1R1O A;  4IU1 A;  3E8Z A;  4IU5 A;  4MYF A;  4RLA A;  4Q3R A;  1HQX A;  3SKK A;  4GWC A;  4IU0 A;  4I06 A;  1WVA A;  1P8P A;  3MFW A;  4G3H A;  3GN0 A;  2PLL A;  1TBL A;  1HQ5 A;  1WVB A;  2PHO A;  1CEV A;  4HWW A;  1WOI A;  3MMR A;  3RLA A;  4IXU A;  4DZ4 A;  1T4P A;  2PHA A;  1T5F A;  1T4T A;  1XFK A;  4CEV A;  5RLA A;  1P8Q A;  3GMZ A;  3SJT A;  3NIP A;  4GSZ A;  4Q41 A;  1ZPG A;  4MXR A;  2CEV A;  1P8O A;  2EIV A;  3THH A;  1TA1 A;  1P8N A;  2A0M A;  1WOG A;  4RHM A;  4IXV A;  4Q3S A;  1T4R A;  4ITY A;  2ZAV A;  3NIO A;  4GSV A;  4IE2 A;  4Q3U A;  1P8S A;  4FCK A;  4Q3R C;  3KV2 A;  2EF5 A;  4RHI A;  3F80 A;  2EF4 A;  3NIQ A;  4IU4 A;  3TF3 A;  4RHJ A;  5CEV A;  1P8R A;  1HQG A;  4Q42 A;  3LHL A;  1T4S A;  4GWD A;  4RHK A;  1ZPE A;  1P8M A;  1WOH A;  4Q3T A;  1HQH A;  4Q40 A;  2RLA A;  3M1R A;  4HZE A;  1HQF A;  3SL1 A;  3CEV A;  4Q3V A;  4MYL A;  3E9B A;  3MFV A;  1TBJ A;  3MJL A;  3DJ8 A;  4MYK A;  4Q3Q A;  4Q3P A;  1T5G A;  3E6V A;  4RHL A;  1TBH A;  1D3V A;  3E6K A;  1RLA A;  3LP4 A;  4FCI A;  3SL0 A;  3E8Q A;  3PZL A;  3THJ A; 
#chains in the Genus database with same CATH topology
 1C3P A;  1T69 A;  4RHQ A;  4BKX B;  4BZ5 A;  3C10 A;  4IE3 A;  3THE A;  1GQ7 A;  2V5X A;  1T64 A;  3EWF A;  4CQF A;  4HXQ A;  1W22 A;  3SFH A;  4IE1 A;  5EFH A;  3TH7 A;  4MYN A;  5DC6 A;  3LP7 A;  5HJ9 A;  5EFJ D;  5HJA A;  3F06 A;  1PQ3 A;  4GSM A;  2AEB A;  1GQ6 A;  1R1O A;  4IU1 A;  3E8Z A;  3EW8 A;  4IU5 A;  4MYF A;  3C0Z A;  4RLA A;  3F07 A;  4RN0 A;  4Q3R A;  5DC8 A;  1HQX A;  5G17 A;  5G0Y A;  3SKK A;  5EEI A;  4GWC A;  4IU0 A;  4I06 A;  1WVA A;  5DC7 A;  1P8P A;  3MFW A;  2VQV A;  4G3H A;  4QA6 A;  3GN0 A;  2PLL A;  1TBL A;  4CBT A;  5ICN B;  4RN1 A;  1HQ5 A;  1WVB A;  2PHO A;  4A69 A;  2V5W A;  3SFF A;  1CEV A;  4HWW A;  1WOI A;  2VQO A;  3MMR A;  4ZUN A;  3RLA A;  4ZUQ A;  3Q9B A;  4IXU A;  4DZ4 A;  5G0I A;  4LY1 A;  1T4P A;  2PHA A;  5G3W A;  1T5F A;  1T4T A;  3EZT A;  1XFK A;  4ZUP A;  4CEV A;  5RLA A;  5EEF A;  5G0J A;  1P8Q A;  3EZP A;  3GMZ A;  3MZ3 A;  2VQW G;  3NIP A;  3SJT A;  5EFK B;  5EFN A;  4GSZ A;  5D1C A;  5FCW A;  4Q41 A;  1ZPG A;  2VQQ A;  5D1B A;  5FUE A;  4MXR A;  2CEV A;  1P8O A;  3MZ7 A;  2EIV A;  3THH A;  1TA1 A;  1P8N A;  2A0M A;  3Q9F A;  1WOG A;  4RHM A;  5A2S A;  4IXV A;  4Q3S A;  2VQM A;  1T4R A;  4QA1 A;  4ITY A;  5IX0 A;  4ZUM A;  1C3S A;  3MZ4 A;  2ZAV A;  3NIO A;  4GSV A;  4IE2 A;  5EF7 A;  5D1D A;  4CBY A;  4Q3U A;  5THV A;  1P8S A;  4FCK A;  4Q3R C;  3KV2 A;  4QA3 A;  5EEK A;  5THU A;  3MZ6 A;  5G11 A;  5G1A A;  3F0R A;  2VQJ A;  2EF5 A;  4RHI A;  5THS A;  3Q9C A;  3F80 A;  5G1C A;  4LXZ A;  5LI3 A;  5EEN A;  1C3R A;  2EF4 A;  3NIQ A;  4QA0 A;  3MAX A;  1T67 A;  4IU4 A;  3TF3 A;  4RHJ A;  3ZNS A;  3C0Y A;  1P8R A;  5CEV A;  1HQG A;  4QA4 A;  3RQD A;  3Q9E A;  5G0X A;  5JI5 A;  5DC5 A;  4Q42 A;  4BZ6 A;  3LHL A;  1T4S A;  5G13 A;  5IWG A;  4GWD A;  5G12 A;  5EEM A;  4RHK A;  4QA5 A;  1ZPE A;  1P8M A;  1WOH A;  4BZ7 A;  1ZZ1 A;  3ZNR A;  4BZ9 A;  5G0H A;  4ZUO A;  4BZ8 A;  4QA7 A;  4RN2 A;  3MEN A;  4Q3T A;  1HQH A;  4Q40 A;  2RLA A;  3M1R A;  4HZE A;  5G0G A;  4QA2 A;  1HQF A;  2GH6 A;  3SL1 A;  5EFG A;  3CEV A;  4Q3V A;  4MYL A;  3E9B A;  3MFV A;  1TBJ A;  5EF8 A;  5EFB D;  1ZZ0 A;  5BWZ A;  3MJL A;  3DJ8 A;  4MYK A;  4Q3Q A;  4Q3P A;  1T5G A;  3E6V A;  4RHL A;  1ZZ3 A;  2VCG A;  1TBH A;  1D3V A;  3E6K A;  1RLA A;  1VKG A;  3LP4 A;  4FCI A;  5G10 A;  5THT A;  3E8Q A;  3SL0 A;  4ZUR A;  5G1B A;  3PZL A;  3THJ A; 
#chains in the Genus database with same CATH homology
 4RHQ A;  4IE3 A;  3THE A;  1GQ7 A;  4HXQ A;  4IE1 A;  3TH7 A;  4MYN A;  3LP7 A;  5HJ9 A;  5HJA A;  1PQ3 A;  4GSM A;  2AEB A;  1GQ6 A;  1R1O A;  4IU1 A;  3E8Z A;  4IU5 A;  4MYF A;  4RLA A;  4Q3R A;  1HQX A;  3SKK A;  4GWC A;  4IU0 A;  4I06 A;  1WVA A;  1P8P A;  3MFW A;  4G3H A;  3GN0 A;  2PLL A;  1TBL A;  1HQ5 A;  1WVB A;  2PHO A;  1CEV A;  4HWW A;  1WOI A;  3MMR A;  3RLA A;  4IXU A;  4DZ4 A;  1T4P A;  2PHA A;  1T5F A;  1T4T A;  1XFK A;  4CEV A;  5RLA A;  1P8Q A;  3GMZ A;  3SJT A;  3NIP A;  4GSZ A;  4Q41 A;  1ZPG A;  4MXR A;  2CEV A;  1P8O A;  2EIV A;  3THH A;  1TA1 A;  1P8N A;  2A0M A;  1WOG A;  4RHM A;  4IXV A;  4Q3S A;  1T4R A;  4ITY A;  2ZAV A;  3NIO A;  4GSV A;  4IE2 A;  4Q3U A;  1P8S A;  4FCK A;  4Q3R C;  3KV2 A;  2EF5 A;  4RHI A;  3F80 A;  2EF4 A;  3NIQ A;  4IU4 A;  3TF3 A;  4RHJ A;  5CEV A;  1P8R A;  1HQG A;  4Q42 A;  3LHL A;  1T4S A;  4GWD A;  4RHK A;  1ZPE A;  1P8M A;  1WOH A;  4Q3T A;  1HQH A;  4Q40 A;  2RLA A;  3M1R A;  4HZE A;  1HQF A;  3SL1 A;  3CEV A;  4Q3V A;  4MYL A;  3E9B A;  3MFV A;  1TBJ A;  3MJL A;  3DJ8 A;  4MYK A;  4Q3Q A;  4Q3P A;  1T5G A;  3E6V A;  4RHL A;  1TBH A;  1D3V A;  3E6K A;  1RLA A;  3LP4 A;  4FCI A;  3SL0 A;  3E8Q A;  3PZL A;  3THJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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