1P8PA

Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase i.
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDNSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase 1
total genus 105
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2003-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1p8pA00
4IE3A 3RLAA 3E6KA 2EF5A 4DZ4A 5CEVA 3E8ZA 1P8MA 2PHOA 1R1OA 1P8RA 2EF4A 1WOGA 4RLAA 3LHLA 2AEBA 4IU0A 1WOHA 1XFKA 5HJ9A 3DJ8A 1HQHA 4FCIA 4Q3QA 4CEVA 3TH7A 4MYKA 1HQXA 4Q42A 3F80A 3NIQA 4IU5A 2EIVA 3SJTA 1RLAA 3GN0A 4RHLA 3SKKA 4RHQA 1GQ6A 4GSMA 4GWCA 4RHJA 4GSZA 1HQ5A 4RHKA 2PLLA 3M1RA 4IE2A 1P8SA 1T5FA 1CEVA 4IU4A 4MYNA 4Q3PA 1GQ7A 3PZLA 4Q3RC 4Q3TA 1WOIA 4HWWA 3NIPA 1TA1A 1HQFA 2CEVA 4Q40A 3SL1A 4FCKA 1ZPGA 1D3VA 3SL0A 4IU1A 1P8QA 1T4PA 3GMZA 3THJA 5HJAA 2A0MA 1P8OA 1T4TA 4Q3VA 4Q3UA 4IXUA 4ITYA 1P8PA 2PHAA 3MFVA 1T5GA 4Q3SA 5RLAA 1T4SA 3MFWA 1TBJA 3E6VA 1TBLA 4MYFA 2RLAA 4HXQA 4MXRA 3THHA 1P8NA 3THEA 3MJLA 1T4RA 4RHMA 3CEVA 4I06A 4HZEA 4Q3RA 4IE1A 1WVBA 1ZPEA 3NIOA 3KV2A 3E8QA 1TBHA 3TF3A 4Q41A 4IXVA 3E9BA 4GWDA 2ZAVA 4MYLA 1WVAA 3LP7A 4GSVA 3LP4A 4RHIA 4G3HA 1PQ3A 1HQGA 3MMRA
chains in the Genus database with same CATH superfamily
4IE3A 4QA1A 5EFBD 3ZNRA 4RN0A 3RLAA 5FCWA 5G1AA 5G10A 3SFHA 5THSA 3E6KA 2EF5A 5EFKB 4DZ4A 5EF8A 5CEVA 3EW8A 3E8ZA 1P8MA 2PHOA 1R1OA 1P8RA 2EF4A 1WOGA 4RLAA 3LHLA 3Q9EA 2AEBA 4IU0A 1WOHA 1XFKA 5HJ9A 3SFFA 3DJ8A 1HQHA 4FCIA 4Q3QA 5G1CA 5G11A 4CEVA 3Q9FA 3TH7A 5G0HA 5G0YA 4QA7A 4ZUNA 4MYKA 1HQXA 1ZZ3A 5EENA 4Q42A 5THUA 3F80A 3NIQA 4IU5A 5EFGA 2VQJA 2EIVA 5IX0A 3Q9CA 3SJTA 1RLAA 3GN0A 5G12A 3MZ6A 4RHLA 3SKKA 4RHQA 1GQ6A 4CQFA 4GSMA 4QA3A 1C3RA 4GWCA 5G0GA 5G3WA 4RHJA 4GSZA 4ZUQA 1HQ5A 4RHKA 2PLLA 3M1RA 4IE2A 1P8SA 5EFHA 5D1DA 1T5FA 1CEVA 5EEIA 5BWZA 5IWGA 3C10A 4IU4A 5EEKA 5EF7A 4ZUOA 4MYNA 1VKGA 5G0JA 4Q3PA 5JI5A 5DC8A 1GQ7A 3MZ4A 3PZLA 2VQOA 4Q3RC 4Q3TA 1WOIA 3ZNSA 3F06A 4HWWA 3NIPA 1TA1A 1HQFA 3EZPA 5EFNA 5D1CA 2CEVA 2VQMA 2VQQA 4Q40A 4ZUMA 4FCKA 5EEMA 3SL1A 1ZPGA 1D3VA 4BZ9A 3SL0A 1W22A 1T69A 5LI3A 2VQWG 4IU1A 1P8QA 4BKXB 2VCGA 1T4PA 4QA5A 3MZ3A 1T67A 3GMZA 3MAXA 4RN1A 3THJA 5HJAA 4QA4A 5EFJD 2A0MA 1P8OA 5A2SA 4CBTA 1T4TA 4Q3VA 4Q3UA 4QA6A 3F07A 4BZ6A 5DC7A 4IXUA 1ZZ0A 5EEFA 4ZUPA 4ITYA 3C0YA 1P8PA 2GH6A 2PHAA 1ZZ1A 1T64A 3MFVA 1T5GA 4Q3SA 4QA0A 5RLAA 1T4SA 5ICNB 3MFWA 1TBJA 3E6VA 4BZ8A 1TBLA 3RQDA 4MYFA 2RLAA 5G17A 4HXQA 4MXRA 5D1BA 2VQVA 3THHA 5G0IA 5THTA 1P8NA 3THEA 5DC6A 3MJLA 1T4RA 4RHMA 3CEVA 4I06A 4HZEA 4Q3RA 2V5WA 4A69A 4IE1A 3EWFA 1WVBA 3EZTA 4LXZA 5G1BA 1C3PA 1ZPEA 3MZ7A 3NIOA 3Q9BA 3KV2A 3E8QA 3MENA 3F0RA 1TBHA 3TF3A 4Q41A 4IXVA 5G13A 3C0ZA 5DC5A 3E9BA 4BZ5A 4GWDA 2ZAVA 4MYLA 4QA2A 1WVAA 3LP7A 4RN2A 5FUEA 4GSVA 3LP4A 4RHIA 4CBYA 4G3HA 4LY1A 4ZURA 1C3SA 1HQGA 1PQ3A 4BZ7A 5THVA 5G0XA 3MMRA 2V5XA
chains in the Genus database with same CATH topology
4IE3A 3RLAA 3E6KA 2EF5A 4DZ4A 5CEVA 3E8ZA 1P8MA 2PHOA 1R1OA 1P8RA 2EF4A 1WOGA 4RLAA 3LHLA 2AEBA 4IU0A 1WOHA 1XFKA 5HJ9A 3DJ8A 1HQHA 4FCIA 4Q3QA 4CEVA 3TH7A 4MYKA 1HQXA 4Q42A 3F80A 3NIQA 4IU5A 2EIVA 3SJTA 1RLAA 3GN0A 4RHLA 3SKKA 4RHQA 1GQ6A 4GSMA 4GWCA 4RHJA 4GSZA 1HQ5A 4RHKA 2PLLA 3M1RA 4IE2A 1P8SA 1T5FA 1CEVA 4IU4A 4MYNA 4Q3PA 1GQ7A 3PZLA 4Q3RC 4Q3TA 1WOIA 4HWWA 3NIPA 1TA1A 1HQFA 2CEVA 4Q40A 3SL1A 4FCKA 1ZPGA 1D3VA 3SL0A 4IU1A 1P8QA 1T4PA 3GMZA 3THJA 5HJAA 2A0MA 1P8OA 1T4TA 4Q3VA 4Q3UA 4IXUA 4ITYA 1P8PA 2PHAA 3MFVA 1T5GA 4Q3SA 5RLAA 1T4SA 3MFWA 1TBJA 3E6VA 1TBLA 4MYFA 2RLAA 4HXQA 4MXRA 3THHA 1P8NA 3THEA 3MJLA 1T4RA 4RHMA 3CEVA 4I06A 4HZEA 4Q3RA 4IE1A 1WVBA 1ZPEA 3NIOA 3KV2A 3E8QA 1TBHA 3TF3A 4Q41A 4IXVA 3E9BA 4GWDA 2ZAVA 4MYLA 1WVAA 3LP7A 4GSVA 3LP4A 4RHIA 4G3HA 1PQ3A 1HQGA 3MMRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IE3 A;  3RLA A;  3E6K A;  2EF5 A;  4DZ4 A;  5CEV A;  3E8Z A;  1P8M A;  2PHO A;  1R1O A;  1P8R A;  2EF4 A;  1WOG A;  4RLA A;  3LHL A;  2AEB A;  4IU0 A;  1WOH A;  1XFK A;  5HJ9 A;  3DJ8 A;  1HQH A;  4FCI A;  4Q3Q A;  4CEV A;  3TH7 A;  4MYK A;  1HQX A;  4Q42 A;  3F80 A;  3NIQ A;  4IU5 A;  2EIV A;  3SJT A;  1RLA A;  3GN0 A;  4RHL A;  3SKK A;  4RHQ A;  1GQ6 A;  4GSM A;  4GWC A;  4RHJ A;  4GSZ A;  1HQ5 A;  4RHK A;  2PLL A;  3M1R A;  4IE2 A;  1P8S A;  1T5F A;  1CEV A;  4IU4 A;  4MYN A;  4Q3P A;  1GQ7 A;  3PZL A;  4Q3R C;  4Q3T A;  1WOI A;  4HWW A;  3NIP A;  1TA1 A;  1HQF A;  2CEV A;  4Q40 A;  3SL1 A;  4FCK A;  1ZPG A;  1D3V A;  3SL0 A;  4IU1 A;  1P8Q A;  1T4P A;  3GMZ A;  3THJ A;  5HJA A;  2A0M A;  1P8O A;  1T4T A;  4Q3V A;  4Q3U A;  4IXU A;  4ITY A;  1P8P A;  2PHA A;  3MFV A;  1T5G A;  4Q3S A;  5RLA A;  1T4S A;  3MFW A;  1TBJ A;  3E6V A;  1TBL A;  4MYF A;  2RLA A;  4HXQ A;  4MXR A;  3THH A;  1P8N A;  3THE A;  3MJL A;  1T4R A;  4RHM A;  3CEV A;  4I06 A;  4HZE A;  4Q3R A;  4IE1 A;  1WVB A;  1ZPE A;  3NIO A;  3KV2 A;  3E8Q A;  1TBH A;  3TF3 A;  4Q41 A;  4IXV A;  3E9B A;  4GWD A;  2ZAV A;  4MYL A;  1WVA A;  3LP7 A;  4GSV A;  3LP4 A;  4RHI A;  4G3H A;  1PQ3 A;  1HQG A;  3MMR A; 
#chains in the Genus database with same CATH topology
 4IE3 A;  4QA1 A;  5EFB D;  3ZNR A;  4RN0 A;  3RLA A;  5FCW A;  5G1A A;  5G10 A;  3SFH A;  5THS A;  3E6K A;  2EF5 A;  5EFK B;  4DZ4 A;  5EF8 A;  5CEV A;  3EW8 A;  3E8Z A;  1P8M A;  2PHO A;  1R1O A;  1P8R A;  2EF4 A;  1WOG A;  4RLA A;  3LHL A;  3Q9E A;  2AEB A;  4IU0 A;  1WOH A;  1XFK A;  5HJ9 A;  3SFF A;  3DJ8 A;  1HQH A;  4FCI A;  4Q3Q A;  5G1C A;  5G11 A;  4CEV A;  3Q9F A;  3TH7 A;  5G0H A;  5G0Y A;  4QA7 A;  4ZUN A;  4MYK A;  1HQX A;  1ZZ3 A;  5EEN A;  4Q42 A;  5THU A;  3F80 A;  3NIQ A;  4IU5 A;  5EFG A;  2VQJ A;  2EIV A;  5IX0 A;  3Q9C A;  3SJT A;  1RLA A;  3GN0 A;  5G12 A;  3MZ6 A;  4RHL A;  3SKK A;  4RHQ A;  1GQ6 A;  4CQF A;  4GSM A;  4QA3 A;  1C3R A;  4GWC A;  5G0G A;  5G3W A;  4RHJ A;  4GSZ A;  4ZUQ A;  1HQ5 A;  4RHK A;  2PLL A;  3M1R A;  4IE2 A;  1P8S A;  5EFH A;  5D1D A;  1T5F A;  1CEV A;  5EEI A;  5BWZ A;  5IWG A;  3C10 A;  4IU4 A;  5EEK A;  5EF7 A;  4ZUO A;  4MYN A;  1VKG A;  5G0J A;  4Q3P A;  5JI5 A;  5DC8 A;  1GQ7 A;  3MZ4 A;  3PZL A;  2VQO A;  4Q3R C;  4Q3T A;  1WOI A;  3ZNS A;  3F06 A;  4HWW A;  3NIP A;  1TA1 A;  1HQF A;  3EZP A;  5EFN A;  5D1C A;  2CEV A;  2VQM A;  2VQQ A;  4Q40 A;  4ZUM A;  4FCK A;  5EEM A;  3SL1 A;  1ZPG A;  1D3V A;  4BZ9 A;  3SL0 A;  1W22 A;  1T69 A;  5LI3 A;  2VQW G;  4IU1 A;  1P8Q A;  4BKX B;  2VCG A;  1T4P A;  4QA5 A;  3MZ3 A;  1T67 A;  3GMZ A;  3MAX A;  4RN1 A;  3THJ A;  5HJA A;  4QA4 A;  5EFJ D;  2A0M A;  1P8O A;  5A2S A;  4CBT A;  1T4T A;  4Q3V A;  4Q3U A;  4QA6 A;  3F07 A;  4BZ6 A;  5DC7 A;  4IXU A;  1ZZ0 A;  5EEF A;  4ZUP A;  4ITY A;  3C0Y A;  1P8P A;  2GH6 A;  2PHA A;  1ZZ1 A;  1T64 A;  3MFV A;  1T5G A;  4Q3S A;  4QA0 A;  5RLA A;  1T4S A;  5ICN B;  3MFW A;  1TBJ A;  3E6V A;  4BZ8 A;  1TBL A;  3RQD A;  4MYF A;  2RLA A;  5G17 A;  4HXQ A;  4MXR A;  5D1B A;  2VQV A;  3THH A;  5G0I A;  5THT A;  1P8N A;  3THE A;  5DC6 A;  3MJL A;  1T4R A;  4RHM A;  3CEV A;  4I06 A;  4HZE A;  4Q3R A;  2V5W A;  4A69 A;  4IE1 A;  3EWF A;  1WVB A;  3EZT A;  4LXZ A;  5G1B A;  1C3P A;  1ZPE A;  3MZ7 A;  3NIO A;  3Q9B A;  3KV2 A;  3E8Q A;  3MEN A;  3F0R A;  1TBH A;  3TF3 A;  4Q41 A;  4IXV A;  5G13 A;  3C0Z A;  5DC5 A;  3E9B A;  4BZ5 A;  4GWD A;  2ZAV A;  4MYL A;  4QA2 A;  1WVA A;  3LP7 A;  4RN2 A;  5FUE A;  4GSV A;  3LP4 A;  4RHI A;  4CBY A;  4G3H A;  4LY1 A;  4ZUR A;  1C3S A;  1HQG A;  1PQ3 A;  4BZ7 A;  5THV A;  5G0X A;  3MMR A;  2V5X A; 
#chains in the Genus database with same CATH homology
 4IE3 A;  3RLA A;  3E6K A;  2EF5 A;  4DZ4 A;  5CEV A;  3E8Z A;  1P8M A;  2PHO A;  1R1O A;  1P8R A;  2EF4 A;  1WOG A;  4RLA A;  3LHL A;  2AEB A;  4IU0 A;  1WOH A;  1XFK A;  5HJ9 A;  3DJ8 A;  1HQH A;  4FCI A;  4Q3Q A;  4CEV A;  3TH7 A;  4MYK A;  1HQX A;  4Q42 A;  3F80 A;  3NIQ A;  4IU5 A;  2EIV A;  3SJT A;  1RLA A;  3GN0 A;  4RHL A;  3SKK A;  4RHQ A;  1GQ6 A;  4GSM A;  4GWC A;  4RHJ A;  4GSZ A;  1HQ5 A;  4RHK A;  2PLL A;  3M1R A;  4IE2 A;  1P8S A;  1T5F A;  1CEV A;  4IU4 A;  4MYN A;  4Q3P A;  1GQ7 A;  3PZL A;  4Q3R C;  4Q3T A;  1WOI A;  4HWW A;  3NIP A;  1TA1 A;  1HQF A;  2CEV A;  4Q40 A;  3SL1 A;  4FCK A;  1ZPG A;  1D3V A;  3SL0 A;  4IU1 A;  1P8Q A;  1T4P A;  3GMZ A;  3THJ A;  5HJA A;  2A0M A;  1P8O A;  1T4T A;  4Q3V A;  4Q3U A;  4IXU A;  4ITY A;  1P8P A;  2PHA A;  3MFV A;  1T5G A;  4Q3S A;  5RLA A;  1T4S A;  3MFW A;  1TBJ A;  3E6V A;  1TBL A;  4MYF A;  2RLA A;  4HXQ A;  4MXR A;  3THH A;  1P8N A;  3THE A;  3MJL A;  1T4R A;  4RHM A;  3CEV A;  4I06 A;  4HZE A;  4Q3R A;  4IE1 A;  1WVB A;  1ZPE A;  3NIO A;  3KV2 A;  3E8Q A;  1TBH A;  3TF3 A;  4Q41 A;  4IXV A;  3E9B A;  4GWD A;  2ZAV A;  4MYL A;  1WVA A;  3LP7 A;  4GSV A;  3LP4 A;  4RHI A;  4G3H A;  1PQ3 A;  1HQG A;  3MMR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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