1TBHA

H141d mutant of rat liver arginase i
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLDGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the role of the hyper-reactive histidine residue of arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase 1
total genus 101
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2004-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1tbhA00
4Q40A 1P8MA 2EIVA 2PHOA 4Q42A 3TH7A 1T4TA 3LP4A 4MYKA 1TBLA 3SL1A 1ZPEA 4MXRA 1P8PA 3THEA 4MYFA 3SKKA 1HQXA 4Q3UA 1WVAA 4Q3SA 3NIPA 4RHKA 4RLAA 3MMRA 4DZ4A 4MYLA 1TA1A 4Q3PA 4Q3RA 1RLAA 3PZLA 3F80A 4Q3TA 1P8SA 1TBHA 3E8ZA 1GQ7A 1TBJA 2EF5A 2CEVA 2RLAA 4IU4A 1T4SA 3GMZA 1WOGA 1D3VA 3E9BA 3MFVA 4FCKA 2PHAA 1WOIA 4IE1A 4Q3VA 3LP7A 4CEVA 3LHLA 2A0MA 3E6VA 2PLLA 4ITYA 4FCIA 1P8RA 4RHQA 4IE2A 1P8QA 1HQ5A 4RHLA 4RHMA 4GWCA 3TF3A 4IU1A 1P8OA 4RHJA 5CEVA 3MFWA 4IXUA 1WOHA 1HQFA 3E8QA 1R1OA 4HWWA 1GQ6A 5HJAA 1XFKA 5RLAA 4RHIA 3SJTA 1T5FA 4GSVA 3SL0A 2AEBA 4IXVA 3RLAA 3NIQA 1HQHA 4Q3QA 3M1RA 3KV2A 3NIOA 4HZEA 1CEVA 3GN0A 4GSMA 4HXQA 4G3HA 1P8NA 2EF4A 2ZAVA 3THJA 4IU0A 3CEVA 4GWDA 3E6KA 1T4RA 1WVBA 1T4PA 4IU5A 3DJ8A 1HQGA 3THHA 1ZPGA 4I06A 4IE3A 4Q3RC 1T5GA 5HJ9A 1PQ3A 4Q41A 4GSZA 4MYNA 3MJLA
chains in the Genus database with same CATH superfamily
3ZNSA 4Q40A 1C3PA 4QA2A 3SFHA 1P8MA 2EIVA 2PHOA 4Q42A 3MZ7A 3MENA 5D1CA 1ZZ3A 3TH7A 3Q9BA 5THSA 1T4TA 3LP4A 5EF8A 4MYKA 5BWZA 3MZ4A 4ZUOA 3MZ3A 1TBLA 4QA4A 4CQFA 4QA0A 3SL1A 2V5XA 5G0YA 1ZPEA 3C0ZA 1C3SA 4LY1A 3F0RA 4MXRA 1P8PA 1C3RA 3THEA 5A2SA 5G11A 5THTA 4MYFA 3SKKA 1HQXA 4Q3UA 3EWFA 1T64A 1WVAA 3NIPA 4Q3SA 5EFJD 4BZ5A 4RHKA 3F07A 3MMRA 4RN1A 4RLAA 4DZ4A 4MYLA 1TA1A 4Q3PA 4Q3RA 3Q9EA 1RLAA 2VQQA 2VQWG 3PZLA 3F80A 4Q3TA 4QA7A 3MAXA 4ZUMA 1P8SA 4A69A 1TBHA 1W22A 4BZ7A 3E8ZA 1GQ7A 5EEMA 5DC8A 5D1DA 5EFNA 1TBJA 5FCWA 5G0GA 2EF5A 5G12A 2CEVA 1ZZ0A 5EF7A 2RLAA 2VQOA 3MZ6A 1T4SA 3GMZA 4IU4A 3EZTA 1WOGA 4CBTA 1D3VA 3E9BA 5G17A 3MFVA 4FCKA 2PHAA 4BZ6A 1WOIA 4IE1A 3EZPA 3LP7A 4Q3VA 4QA6A 5G0XA 5DC7A 3LHLA 2A0MA 3E6VA 2PLLA 4ITYA 4RN0A 5ICNB 2GH6A 4FCIA 1P8RA 5EEFA 4RHQA 5G0IA 4IE2A 4LXZA 1P8QA 1HQ5A 5G1AA 5EENA 4RHLA 5G10A 4RHMA 2VQJA 4GWCA 3ZNRA 3TF3A 4ZURA 3SFFA 4IU1A 1P8OA 4RHJA 5G0HA 5CEVA 5D1BA 3C10A 3MFWA 5FUEA 4IXUA 1WOHA 1HQFA 3E8QA 1R1OA 4ZUNA 4BZ9A 1ZZ1A 4HWWA 5DC5A 4CBYA 4ZUPA 1GQ6A 5HJAA 1XFKA 4RN2A 5RLAA 4BZ8A 4RHIA 1T69A 5G1BA 3SJTA 1T5FA 4GSVA 3SL0A 5DC6A 2AEBA 4QA1A 4IXVA 2VQMA 3Q9CA 4QA5A 5G0JA 3RLAA 3NIQA 1HQHA 4Q3QA 3M1RA 3KV2A 3NIOA 1VKGA 1CEVA 3GN0A 4HZEA 4BKXB 4GSMA 4HXQA 5EEKA 3RQDA 4G3HA 1P8NA 1T67A 2EF4A 2ZAVA 5THUA 3THJA 2VQVA 4IU0A 5EFBD 3CEVA 4GWDA 5EEIA 3C0YA 5THVA 4ZUQA 5IWGA 3E6KA 1T4RA 1WVBA 3F06A 5LI3A 1T4PA 5G3WA 5G13A 5JI5A 4QA3A 5EFHA 5IX0A 4IU5A 3DJ8A 1HQGA 2VCGA 3EW8A 3THHA 5EFGA 1ZPGA 4I06A 4IE3A 4Q3RC 1T5GA 5HJ9A 3Q9FA 1PQ3A 2V5WA 5EFKB 5G1CA 4GSZA 4Q41A 4MYNA 3MJLA 4CEVA
chains in the Genus database with same CATH topology
4Q40A 1P8MA 2EIVA 2PHOA 4Q42A 3TH7A 1T4TA 3LP4A 4MYKA 1TBLA 3SL1A 1ZPEA 4MXRA 1P8PA 3THEA 4MYFA 3SKKA 1HQXA 4Q3UA 1WVAA 4Q3SA 3NIPA 4RHKA 4RLAA 3MMRA 4DZ4A 4MYLA 1TA1A 4Q3PA 4Q3RA 1RLAA 3PZLA 3F80A 4Q3TA 1P8SA 1TBHA 3E8ZA 1GQ7A 1TBJA 2EF5A 2CEVA 2RLAA 4IU4A 1T4SA 3GMZA 1WOGA 1D3VA 3E9BA 3MFVA 4FCKA 2PHAA 1WOIA 4IE1A 4Q3VA 3LP7A 4CEVA 3LHLA 2A0MA 3E6VA 2PLLA 4ITYA 4FCIA 1P8RA 4RHQA 4IE2A 1P8QA 1HQ5A 4RHLA 4RHMA 4GWCA 3TF3A 4IU1A 1P8OA 4RHJA 5CEVA 3MFWA 4IXUA 1WOHA 1HQFA 3E8QA 1R1OA 4HWWA 1GQ6A 5HJAA 1XFKA 5RLAA 4RHIA 3SJTA 1T5FA 4GSVA 3SL0A 2AEBA 4IXVA 3RLAA 3NIQA 1HQHA 4Q3QA 3M1RA 3KV2A 3NIOA 4HZEA 1CEVA 3GN0A 4GSMA 4HXQA 4G3HA 1P8NA 2EF4A 2ZAVA 3THJA 4IU0A 3CEVA 4GWDA 3E6KA 1T4RA 1WVBA 1T4PA 4IU5A 3DJ8A 1HQGA 3THHA 1ZPGA 4I06A 4IE3A 4Q3RC 1T5GA 5HJ9A 1PQ3A 4Q41A 4GSZA 4MYNA 3MJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q40 A;  1P8M A;  2EIV A;  2PHO A;  4Q42 A;  3TH7 A;  1T4T A;  3LP4 A;  4MYK A;  1TBL A;  3SL1 A;  1ZPE A;  4MXR A;  1P8P A;  3THE A;  4MYF A;  3SKK A;  1HQX A;  4Q3U A;  1WVA A;  4Q3S A;  3NIP A;  4RHK A;  4RLA A;  3MMR A;  4DZ4 A;  4MYL A;  1TA1 A;  4Q3P A;  4Q3R A;  1RLA A;  3PZL A;  3F80 A;  4Q3T A;  1P8S A;  1TBH A;  3E8Z A;  1GQ7 A;  1TBJ A;  2EF5 A;  2CEV A;  2RLA A;  4IU4 A;  1T4S A;  3GMZ A;  1WOG A;  1D3V A;  3E9B A;  3MFV A;  4FCK A;  2PHA A;  1WOI A;  4IE1 A;  4Q3V A;  3LP7 A;  4CEV A;  3LHL A;  2A0M A;  3E6V A;  2PLL A;  4ITY A;  4FCI A;  1P8R A;  4RHQ A;  4IE2 A;  1P8Q A;  1HQ5 A;  4RHL A;  4RHM A;  4GWC A;  3TF3 A;  4IU1 A;  1P8O A;  4RHJ A;  5CEV A;  3MFW A;  4IXU A;  1WOH A;  1HQF A;  3E8Q A;  1R1O A;  4HWW A;  1GQ6 A;  5HJA A;  1XFK A;  5RLA A;  4RHI A;  3SJT A;  1T5F A;  4GSV A;  3SL0 A;  2AEB A;  4IXV A;  3RLA A;  3NIQ A;  1HQH A;  4Q3Q A;  3M1R A;  3KV2 A;  3NIO A;  4HZE A;  1CEV A;  3GN0 A;  4GSM A;  4HXQ A;  4G3H A;  1P8N A;  2EF4 A;  2ZAV A;  3THJ A;  4IU0 A;  3CEV A;  4GWD A;  3E6K A;  1T4R A;  1WVB A;  1T4P A;  4IU5 A;  3DJ8 A;  1HQG A;  3THH A;  1ZPG A;  4I06 A;  4IE3 A;  4Q3R C;  1T5G A;  5HJ9 A;  1PQ3 A;  4Q41 A;  4GSZ A;  4MYN A;  3MJL A; 
#chains in the Genus database with same CATH topology
 3ZNS A;  4Q40 A;  1C3P A;  4QA2 A;  3SFH A;  1P8M A;  2EIV A;  2PHO A;  4Q42 A;  3MZ7 A;  3MEN A;  5D1C A;  1ZZ3 A;  3TH7 A;  3Q9B A;  5THS A;  1T4T A;  3LP4 A;  5EF8 A;  4MYK A;  5BWZ A;  3MZ4 A;  4ZUO A;  3MZ3 A;  1TBL A;  4QA4 A;  4CQF A;  4QA0 A;  3SL1 A;  2V5X A;  5G0Y A;  1ZPE A;  3C0Z A;  1C3S A;  4LY1 A;  3F0R A;  4MXR A;  1P8P A;  1C3R A;  3THE A;  5A2S A;  5G11 A;  5THT A;  4MYF A;  3SKK A;  1HQX A;  4Q3U A;  3EWF A;  1T64 A;  1WVA A;  3NIP A;  4Q3S A;  5EFJ D;  4BZ5 A;  4RHK A;  3F07 A;  3MMR A;  4RN1 A;  4RLA A;  4DZ4 A;  4MYL A;  1TA1 A;  4Q3P A;  4Q3R A;  3Q9E A;  1RLA A;  2VQQ A;  2VQW G;  3PZL A;  3F80 A;  4Q3T A;  4QA7 A;  3MAX A;  4ZUM A;  1P8S A;  4A69 A;  1TBH A;  1W22 A;  4BZ7 A;  3E8Z A;  1GQ7 A;  5EEM A;  5DC8 A;  5D1D A;  5EFN A;  1TBJ A;  5FCW A;  5G0G A;  2EF5 A;  5G12 A;  2CEV A;  1ZZ0 A;  5EF7 A;  2RLA A;  2VQO A;  3MZ6 A;  1T4S A;  3GMZ A;  4IU4 A;  3EZT A;  1WOG A;  4CBT A;  1D3V A;  3E9B A;  5G17 A;  3MFV A;  4FCK A;  2PHA A;  4BZ6 A;  1WOI A;  4IE1 A;  3EZP A;  3LP7 A;  4Q3V A;  4QA6 A;  5G0X A;  5DC7 A;  3LHL A;  2A0M A;  3E6V A;  2PLL A;  4ITY A;  4RN0 A;  5ICN B;  2GH6 A;  4FCI A;  1P8R A;  5EEF A;  4RHQ A;  5G0I A;  4IE2 A;  4LXZ A;  1P8Q A;  1HQ5 A;  5G1A A;  5EEN A;  4RHL A;  5G10 A;  4RHM A;  2VQJ A;  4GWC A;  3ZNR A;  3TF3 A;  4ZUR A;  3SFF A;  4IU1 A;  1P8O A;  4RHJ A;  5G0H A;  5CEV A;  5D1B A;  3C10 A;  3MFW A;  5FUE A;  4IXU A;  1WOH A;  1HQF A;  3E8Q A;  1R1O A;  4ZUN A;  4BZ9 A;  1ZZ1 A;  4HWW A;  5DC5 A;  4CBY A;  4ZUP A;  1GQ6 A;  5HJA A;  1XFK A;  4RN2 A;  5RLA A;  4BZ8 A;  4RHI A;  1T69 A;  5G1B A;  3SJT A;  1T5F A;  4GSV A;  3SL0 A;  5DC6 A;  2AEB A;  4QA1 A;  4IXV A;  2VQM A;  3Q9C A;  4QA5 A;  5G0J A;  3RLA A;  3NIQ A;  1HQH A;  4Q3Q A;  3M1R A;  3KV2 A;  3NIO A;  1VKG A;  1CEV A;  3GN0 A;  4HZE A;  4BKX B;  4GSM A;  4HXQ A;  5EEK A;  3RQD A;  4G3H A;  1P8N A;  1T67 A;  2EF4 A;  2ZAV A;  5THU A;  3THJ A;  2VQV A;  4IU0 A;  5EFB D;  3CEV A;  4GWD A;  5EEI A;  3C0Y A;  5THV A;  4ZUQ A;  5IWG A;  3E6K A;  1T4R A;  1WVB A;  3F06 A;  5LI3 A;  1T4P A;  5G3W A;  5G13 A;  5JI5 A;  4QA3 A;  5EFH A;  5IX0 A;  4IU5 A;  3DJ8 A;  1HQG A;  2VCG A;  3EW8 A;  3THH A;  5EFG A;  1ZPG A;  4I06 A;  4IE3 A;  4Q3R C;  1T5G A;  5HJ9 A;  3Q9F A;  1PQ3 A;  2V5W A;  5EFK B;  5G1C A;  4GSZ A;  4Q41 A;  4MYN A;  3MJL A;  4CEV A; 
#chains in the Genus database with same CATH homology
 4Q40 A;  1P8M A;  2EIV A;  2PHO A;  4Q42 A;  3TH7 A;  1T4T A;  3LP4 A;  4MYK A;  1TBL A;  3SL1 A;  1ZPE A;  4MXR A;  1P8P A;  3THE A;  4MYF A;  3SKK A;  1HQX A;  4Q3U A;  1WVA A;  4Q3S A;  3NIP A;  4RHK A;  4RLA A;  3MMR A;  4DZ4 A;  4MYL A;  1TA1 A;  4Q3P A;  4Q3R A;  1RLA A;  3PZL A;  3F80 A;  4Q3T A;  1P8S A;  1TBH A;  3E8Z A;  1GQ7 A;  1TBJ A;  2EF5 A;  2CEV A;  2RLA A;  4IU4 A;  1T4S A;  3GMZ A;  1WOG A;  1D3V A;  3E9B A;  3MFV A;  4FCK A;  2PHA A;  1WOI A;  4IE1 A;  4Q3V A;  3LP7 A;  4CEV A;  3LHL A;  2A0M A;  3E6V A;  2PLL A;  4ITY A;  4FCI A;  1P8R A;  4RHQ A;  4IE2 A;  1P8Q A;  1HQ5 A;  4RHL A;  4RHM A;  4GWC A;  3TF3 A;  4IU1 A;  1P8O A;  4RHJ A;  5CEV A;  3MFW A;  4IXU A;  1WOH A;  1HQF A;  3E8Q A;  1R1O A;  4HWW A;  1GQ6 A;  5HJA A;  1XFK A;  5RLA A;  4RHI A;  3SJT A;  1T5F A;  4GSV A;  3SL0 A;  2AEB A;  4IXV A;  3RLA A;  3NIQ A;  1HQH A;  4Q3Q A;  3M1R A;  3KV2 A;  3NIO A;  4HZE A;  1CEV A;  3GN0 A;  4GSM A;  4HXQ A;  4G3H A;  1P8N A;  2EF4 A;  2ZAV A;  3THJ A;  4IU0 A;  3CEV A;  4GWD A;  3E6K A;  1T4R A;  1WVB A;  1T4P A;  4IU5 A;  3DJ8 A;  1HQG A;  3THH A;  1ZPG A;  4I06 A;  4IE3 A;  4Q3R C;  1T5G A;  5HJ9 A;  1PQ3 A;  4Q41 A;  4GSZ A;  4MYN A;  3MJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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