1ZPGA

Arginase i covalently modified with propylamine at q19c
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
314
structure length
313
Chain Sequence
KPIEIIGAPFSKGPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLAVIWVDAHTDINTPLTTSSGNLAGQPVAFLLKELKGKFPDVPGFSWVTPAISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSAFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the role of the hyper-reactive histidine residue of arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase 1
total genus 114
structure length 313
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2005-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1zpgA00
4I06A 3PZLA 1D3VA 4HXQA 1PQ3A 3E6KA 2PHAA 4RHJA 4DZ4A 1P8PA 4MYNA 4FCKA 4MYLA 1ZPEA 3LP4A 2CEVA 1RLAA 2RLAA 3NIQA 4Q3QA 1HQXA 1P8SA 3LHLA 2ZAVA 4MYFA 1CEVA 4HWWA 3MMRA 4RHMA 3CEVA 4Q3SA 4IE2A 3TH7A 3THEA 3SJTA 1T5GA 3THHA 1P8NA 5CEVA 1GQ7A 4Q3RA 4Q42A 1P8MA 2EF4A 1TBJA 3RLAA 4GWCA 3NIOA 4Q3VA 4IU5A 4RLAA 4RHIA 4Q3TA 3F80A 1WOGA 4MYKA 2EF5A 4GSMA 1HQFA 4GSVA 3MJLA 2PLLA 4HZEA 3KV2A 3E8ZA 3TF3A 1P8QA 4IXVA 4IU1A 3GMZA 1WVBA 1HQHA 1T4PA 4Q3RC 4MXRA 1T5FA 4IXUA 3E9BA 1T4TA 4FCIA 4RHLA 4IE1A 3THJA 1T4SA 4IE3A 4ITYA 2PHOA 4RHKA 4GWDA 4CEVA 3LP7A 1R1OA 4IU4A 4Q3UA 1XFKA 3SKKA 2EIVA 1TA1A 1ZPGA 3NIPA 1WVAA 5HJAA 3SL1A 1P8RA 4G3HA 5RLAA 3E6VA 1P8OA 3MFWA 4Q3PA 4Q40A 2A0MA 4GSZA 1WOHA 3GN0A 4IU0A 1HQ5A 1HQGA 1TBLA 3SL0A 3DJ8A 2AEBA 4RHQA 1TBHA 4Q41A 3MFVA 1GQ6A 1WOIA 3M1RA 5HJ9A 1T4RA 3E8QA
chains in the Genus database with same CATH superfamily
4I06A 2VCGA 5G11A 3PZLA 4CBYA 1D3VA 4HXQA 1PQ3A 3E6KA 2PHAA 5DC7A 5FCWA 4RHJA 4DZ4A 3Q9CA 1P8PA 4MYNA 4FCKA 4MYLA 1ZPEA 2V5WA 3LP4A 3EWFA 2CEVA 1RLAA 2RLAA 3EZPA 5EF7A 3NIQA 4Q3QA 3MZ3A 1HQXA 1P8SA 4BZ5A 3SFHA 3Q9EA 3LHLA 5THTA 2ZAVA 4MYFA 1CEVA 4ZUOA 4HWWA 3MMRA 5D1BA 4RHMA 3CEVA 5FUEA 2VQOA 4Q3SA 4IE2A 5EEMA 5G1AA 4QA2A 3SJTA 1T5GA 3TH7A 3THEA 3THHA 1P8NA 1W22A 5CEVA 1GQ7A 4Q3RA 5EF8A 5G1CA 5EEKA 3F06A 3MAXA 4Q42A 1T67A 1C3SA 1P8MA 2EF4A 5G1BA 5THUA 1TBJA 2GH6A 3RLAA 4GWCA 5IX0A 1C3RA 3NIOA 4Q3VA 4IU5A 4RLAA 2VQWG 4RHIA 5EFNA 4Q3TA 3F80A 5D1DA 1WOGA 4MYKA 4BZ9A 2EF5A 3C0YA 3Q9BA 4BKXB 4GSMA 1HQFA 4GSVA 4ZUNA 5G0GA 4BZ7A 3C10A 5IWGA 1T64A 1VKGA 3MJLA 3Q9FA 5G0YA 2PLLA 5G0JA 5EFJD 4HZEA 3KV2A 3E8ZA 3ZNSA 3TF3A 5G0IA 1P8QA 1T69A 4IXVA 5G0XA 4QA4A 4IU1A 3GMZA 3EW8A 4QA5A 4RN0A 4RN2A 1WVBA 3MZ4A 1HQHA 1T4PA 2VQVA 5D1CA 4Q3RC 4ZUPA 4BZ8A 5LI3A 2V5XA 1T5FA 4MXRA 4A69A 5EFGA 5G12A 4IXUA 5G13A 5JI5A 3F0RA 3E9BA 2VQQA 5ICNB 3SFFA 5DC6A 1T4TA 4FCIA 5G0HA 4RHLA 4QA0A 4ZUQA 2VQJA 4IE1A 3THJA 1ZZ0A 1T4SA 4IE3A 2VQMA 4ITYA 2PHOA 4RHKA 5EEIA 4GWDA 4LXZA 3LP7A 1R1OA 4IU4A 4Q3UA 4CEVA 1XFKA 3SKKA 2EIVA 4LY1A 5DC8A 3ZNRA 1TA1A 1ZPGA 3NIPA 4QA7A 4RN1A 4CBTA 5DC5A 1WVAA 5HJAA 3SL1A 5A2SA 3F07A 4QA1A 1P8RA 1ZZ1A 4G3HA 5RLAA 5EFKB 4QA3A 5G10A 5THSA 4ZURA 5BWZA 3E6VA 1P8OA 3MFWA 4Q3PA 1ZZ3A 2A0MA 3MZ7A 4GSZA 4Q40A 5EEFA 4ZUMA 4CQFA 1WOHA 3GN0A 4IU0A 5EFHA 1HQ5A 1HQGA 1TBLA 5G17A 3SL0A 3DJ8A 1C3PA 5EFBD 5EENA 2AEBA 3EZTA 4RHQA 3MZ6A 1TBHA 5G3WA 4Q41A 3MFVA 1GQ6A 3MENA 1WOIA 4QA6A 5THVA 3M1RA 5HJ9A 4BZ6A 3RQDA 1T4RA 3C0ZA 3E8QA
chains in the Genus database with same CATH topology
4I06A 3PZLA 1D3VA 4HXQA 1PQ3A 3E6KA 2PHAA 4RHJA 4DZ4A 1P8PA 4MYNA 4FCKA 4MYLA 1ZPEA 3LP4A 2CEVA 1RLAA 2RLAA 3NIQA 4Q3QA 1HQXA 1P8SA 3LHLA 2ZAVA 4MYFA 1CEVA 4HWWA 3MMRA 4RHMA 3CEVA 4Q3SA 4IE2A 3TH7A 3THEA 3SJTA 1T5GA 3THHA 1P8NA 5CEVA 1GQ7A 4Q3RA 4Q42A 1P8MA 2EF4A 1TBJA 3RLAA 4GWCA 3NIOA 4Q3VA 4IU5A 4RLAA 4RHIA 4Q3TA 3F80A 1WOGA 4MYKA 2EF5A 4GSMA 1HQFA 4GSVA 3MJLA 2PLLA 4HZEA 3KV2A 3E8ZA 3TF3A 1P8QA 4IXVA 4IU1A 3GMZA 1WVBA 1HQHA 1T4PA 4Q3RC 4MXRA 1T5FA 4IXUA 3E9BA 1T4TA 4FCIA 4RHLA 4IE1A 3THJA 1T4SA 4IE3A 4ITYA 2PHOA 4RHKA 4GWDA 4CEVA 3LP7A 1R1OA 4IU4A 4Q3UA 1XFKA 3SKKA 2EIVA 1TA1A 1ZPGA 3NIPA 1WVAA 5HJAA 3SL1A 1P8RA 4G3HA 5RLAA 3E6VA 1P8OA 3MFWA 4Q3PA 4Q40A 2A0MA 4GSZA 1WOHA 3GN0A 4IU0A 1HQ5A 1HQGA 1TBLA 3SL0A 3DJ8A 2AEBA 4RHQA 1TBHA 4Q41A 3MFVA 1GQ6A 1WOIA 3M1RA 5HJ9A 1T4RA 3E8QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I06 A;  3PZL A;  1D3V A;  4HXQ A;  1PQ3 A;  3E6K A;  2PHA A;  4RHJ A;  4DZ4 A;  1P8P A;  4MYN A;  4FCK A;  4MYL A;  1ZPE A;  3LP4 A;  2CEV A;  1RLA A;  2RLA A;  3NIQ A;  4Q3Q A;  1HQX A;  1P8S A;  3LHL A;  2ZAV A;  4MYF A;  1CEV A;  4HWW A;  3MMR A;  4RHM A;  3CEV A;  4Q3S A;  4IE2 A;  3TH7 A;  3THE A;  3SJT A;  1T5G A;  3THH A;  1P8N A;  5CEV A;  1GQ7 A;  4Q3R A;  4Q42 A;  1P8M A;  2EF4 A;  1TBJ A;  3RLA A;  4GWC A;  3NIO A;  4Q3V A;  4IU5 A;  4RLA A;  4RHI A;  4Q3T A;  3F80 A;  1WOG A;  4MYK A;  2EF5 A;  4GSM A;  1HQF A;  4GSV A;  3MJL A;  2PLL A;  4HZE A;  3KV2 A;  3E8Z A;  3TF3 A;  1P8Q A;  4IXV A;  4IU1 A;  3GMZ A;  1WVB A;  1HQH A;  1T4P A;  4Q3R C;  4MXR A;  1T5F A;  4IXU A;  3E9B A;  1T4T A;  4FCI A;  4RHL A;  4IE1 A;  3THJ A;  1T4S A;  4IE3 A;  4ITY A;  2PHO A;  4RHK A;  4GWD A;  4CEV A;  3LP7 A;  1R1O A;  4IU4 A;  4Q3U A;  1XFK A;  3SKK A;  2EIV A;  1TA1 A;  1ZPG A;  3NIP A;  1WVA A;  5HJA A;  3SL1 A;  1P8R A;  4G3H A;  5RLA A;  3E6V A;  1P8O A;  3MFW A;  4Q3P A;  4Q40 A;  2A0M A;  4GSZ A;  1WOH A;  3GN0 A;  4IU0 A;  1HQ5 A;  1HQG A;  1TBL A;  3SL0 A;  3DJ8 A;  2AEB A;  4RHQ A;  1TBH A;  4Q41 A;  3MFV A;  1GQ6 A;  1WOI A;  3M1R A;  5HJ9 A;  1T4R A;  3E8Q A; 
#chains in the Genus database with same CATH topology
 4I06 A;  2VCG A;  5G11 A;  3PZL A;  4CBY A;  1D3V A;  4HXQ A;  1PQ3 A;  3E6K A;  2PHA A;  5DC7 A;  5FCW A;  4RHJ A;  4DZ4 A;  3Q9C A;  1P8P A;  4MYN A;  4FCK A;  4MYL A;  1ZPE A;  2V5W A;  3LP4 A;  3EWF A;  2CEV A;  1RLA A;  2RLA A;  3EZP A;  5EF7 A;  3NIQ A;  4Q3Q A;  3MZ3 A;  1HQX A;  1P8S A;  4BZ5 A;  3SFH A;  3Q9E A;  3LHL A;  5THT A;  2ZAV A;  4MYF A;  1CEV A;  4ZUO A;  4HWW A;  3MMR A;  5D1B A;  4RHM A;  3CEV A;  5FUE A;  2VQO A;  4Q3S A;  4IE2 A;  5EEM A;  5G1A A;  4QA2 A;  3SJT A;  1T5G A;  3TH7 A;  3THE A;  3THH A;  1P8N A;  1W22 A;  5CEV A;  1GQ7 A;  4Q3R A;  5EF8 A;  5G1C A;  5EEK A;  3F06 A;  3MAX A;  4Q42 A;  1T67 A;  1C3S A;  1P8M A;  2EF4 A;  5G1B A;  5THU A;  1TBJ A;  2GH6 A;  3RLA A;  4GWC A;  5IX0 A;  1C3R A;  3NIO A;  4Q3V A;  4IU5 A;  4RLA A;  2VQW G;  4RHI A;  5EFN A;  4Q3T A;  3F80 A;  5D1D A;  1WOG A;  4MYK A;  4BZ9 A;  2EF5 A;  3C0Y A;  3Q9B A;  4BKX B;  4GSM A;  1HQF A;  4GSV A;  4ZUN A;  5G0G A;  4BZ7 A;  3C10 A;  5IWG A;  1T64 A;  1VKG A;  3MJL A;  3Q9F A;  5G0Y A;  2PLL A;  5G0J A;  5EFJ D;  4HZE A;  3KV2 A;  3E8Z A;  3ZNS A;  3TF3 A;  5G0I A;  1P8Q A;  1T69 A;  4IXV A;  5G0X A;  4QA4 A;  4IU1 A;  3GMZ A;  3EW8 A;  4QA5 A;  4RN0 A;  4RN2 A;  1WVB A;  3MZ4 A;  1HQH A;  1T4P A;  2VQV A;  5D1C A;  4Q3R C;  4ZUP A;  4BZ8 A;  5LI3 A;  2V5X A;  1T5F A;  4MXR A;  4A69 A;  5EFG A;  5G12 A;  4IXU A;  5G13 A;  5JI5 A;  3F0R A;  3E9B A;  2VQQ A;  5ICN B;  3SFF A;  5DC6 A;  1T4T A;  4FCI A;  5G0H A;  4RHL A;  4QA0 A;  4ZUQ A;  2VQJ A;  4IE1 A;  3THJ A;  1ZZ0 A;  1T4S A;  4IE3 A;  2VQM A;  4ITY A;  2PHO A;  4RHK A;  5EEI A;  4GWD A;  4LXZ A;  3LP7 A;  1R1O A;  4IU4 A;  4Q3U A;  4CEV A;  1XFK A;  3SKK A;  2EIV A;  4LY1 A;  5DC8 A;  3ZNR A;  1TA1 A;  1ZPG A;  3NIP A;  4QA7 A;  4RN1 A;  4CBT A;  5DC5 A;  1WVA A;  5HJA A;  3SL1 A;  5A2S A;  3F07 A;  4QA1 A;  1P8R A;  1ZZ1 A;  4G3H A;  5RLA A;  5EFK B;  4QA3 A;  5G10 A;  5THS A;  4ZUR A;  5BWZ A;  3E6V A;  1P8O A;  3MFW A;  4Q3P A;  1ZZ3 A;  2A0M A;  3MZ7 A;  4GSZ A;  4Q40 A;  5EEF A;  4ZUM A;  4CQF A;  1WOH A;  3GN0 A;  4IU0 A;  5EFH A;  1HQ5 A;  1HQG A;  1TBL A;  5G17 A;  3SL0 A;  3DJ8 A;  1C3P A;  5EFB D;  5EEN A;  2AEB A;  3EZT A;  4RHQ A;  3MZ6 A;  1TBH A;  5G3W A;  4Q41 A;  3MFV A;  1GQ6 A;  3MEN A;  1WOI A;  4QA6 A;  5THV A;  3M1R A;  5HJ9 A;  4BZ6 A;  3RQD A;  1T4R A;  3C0Z A;  3E8Q A; 
#chains in the Genus database with same CATH homology
 4I06 A;  3PZL A;  1D3V A;  4HXQ A;  1PQ3 A;  3E6K A;  2PHA A;  4RHJ A;  4DZ4 A;  1P8P A;  4MYN A;  4FCK A;  4MYL A;  1ZPE A;  3LP4 A;  2CEV A;  1RLA A;  2RLA A;  3NIQ A;  4Q3Q A;  1HQX A;  1P8S A;  3LHL A;  2ZAV A;  4MYF A;  1CEV A;  4HWW A;  3MMR A;  4RHM A;  3CEV A;  4Q3S A;  4IE2 A;  3TH7 A;  3THE A;  3SJT A;  1T5G A;  3THH A;  1P8N A;  5CEV A;  1GQ7 A;  4Q3R A;  4Q42 A;  1P8M A;  2EF4 A;  1TBJ A;  3RLA A;  4GWC A;  3NIO A;  4Q3V A;  4IU5 A;  4RLA A;  4RHI A;  4Q3T A;  3F80 A;  1WOG A;  4MYK A;  2EF5 A;  4GSM A;  1HQF A;  4GSV A;  3MJL A;  2PLL A;  4HZE A;  3KV2 A;  3E8Z A;  3TF3 A;  1P8Q A;  4IXV A;  4IU1 A;  3GMZ A;  1WVB A;  1HQH A;  1T4P A;  4Q3R C;  4MXR A;  1T5F A;  4IXU A;  3E9B A;  1T4T A;  4FCI A;  4RHL A;  4IE1 A;  3THJ A;  1T4S A;  4IE3 A;  4ITY A;  2PHO A;  4RHK A;  4GWD A;  4CEV A;  3LP7 A;  1R1O A;  4IU4 A;  4Q3U A;  1XFK A;  3SKK A;  2EIV A;  1TA1 A;  1ZPG A;  3NIP A;  1WVA A;  5HJA A;  3SL1 A;  1P8R A;  4G3H A;  5RLA A;  3E6V A;  1P8O A;  3MFW A;  4Q3P A;  4Q40 A;  2A0M A;  4GSZ A;  1WOH A;  3GN0 A;  4IU0 A;  1HQ5 A;  1HQG A;  1TBL A;  3SL0 A;  3DJ8 A;  2AEB A;  4RHQ A;  1TBH A;  4Q41 A;  3MFV A;  1GQ6 A;  1WOI A;  3M1R A;  5HJ9 A;  1T4R A;  3E8Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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