1ZZ0A

Crystal structure of a hdac-like protein with acetate bound
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
367
structure length
367
Chain Sequence
AIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLPALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a bacterial class 2 histone deacetylase homologue
pubmed doi rcsb
molecule tags Hydrolase
source organism Alcaligenaceae bacterium
molecule keywords Histone deacetylase-like amidohydrolase
total genus 136
structure length 367
sequence length 367
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.-:
pdb deposition date 2005-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00850 Hist_deacetyl Histone deacetylase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.20 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Histone deacetylase domain 1zz0A00
3C0ZA 5EF8A 4A69A 5G1BA 4ZUNA 4RN1A 5G10A 3EWFA 5D1DA 5THTA 3MZ3A 3EZPA 5G13A 5JI5A 3Q9BA 1C3RA 3C0YA 5G12A 1W22A 5THSA 5DC5A 3C10A 2V5WA 5FCWA 3MZ7A 3ZNRA 5THUA 5IWGA 4ZUMA 4CQFA 1ZZ3A 5FUEA 4RN2A 5G0HA 4CBTA 4CBYA 5G11A 3MZ6A 5EFJD 2VQJA 5LI3A 1C3SA 1T69A 3SFHA 4QA0A 5DC7A 4BZ5A 1VKGA 5THVA 3ZNSA 5G17A 5G1CA 2GH6A 5D1CA 4RN0A 4BZ8A 5G0GA 1T67A 2VQWG 2VQOA 5EFNA 5EFKB 5ICNB 3F06A 4LY1A 4LXZA 2V5XA 4QA6A 5EENA 4QA4A 4QA5A 3Q9CA 1T64A 3SFFA 5G0JA 5G0IA 5G1AA 2VQQA 5A2SA 1C3PA 4QA3A 4ZUPA 3Q9EA 4BKXB 5EEMA 4ZUQA 1ZZ0A 3Q9FA 3RQDA 3MZ4A 5D1BA 3EW8A 5BWZA 3F0RA 5EFBD 4ZURA 5DC8A 4BZ6A 3MAXA 4QA1A 2VCGA 5EEIA 5EEFA 5EFGA 5G0YA 2VQVA 3MENA 5G3WA 5DC6A 5EF7A 3F07A 4QA2A 4BZ7A 4QA7A 5EFHA 1ZZ1A 2VQMA 4BZ9A 5EEKA 3EZTA 4ZUOA 5IX0A 5G0XA
chains in the Genus database with same CATH superfamily
3C0ZA 5EF8A 4A69A 1TBLA 3RLAA 5G1BA 4ZUNA 4RN1A 1TA1A 3EWFA 4RHKA 5D1DA 5G10A 5CEVA 4RHQA 4GWCA 5THTA 1WVBA 3MZ3A 4GSVA 1XFKA 4IE2A 3E6KA 3SL0A 1T4SA 2RLAA 3EZPA 5G13A 3THEA 5JI5A 3Q9BA 1WVAA 3E8ZA 1C3RA 3C0YA 4Q41A 4MXRA 2EIVA 5G12A 1GQ7A 1W22A 5THSA 1T5FA 4Q3RA 5DC5A 3C10A 4ITYA 2V5WA 5FCWA 2PHOA 4GSMA 3MZ7A 3ZNRA 4GWDA 5THUA 4HWWA 4RHMA 1T4PA 5IWGA 4ZUMA 4MYNA 3LP7A 4CQFA 1ZZ3A 3GMZA 5FUEA 3LP4A 3SKKA 4RN2A 5G0HA 4MYFA 4CBTA 2CEVA 4CBYA 1WOHA 3CEVA 3TF3A 5G11A 4IE3A 3MZ6A 4IE1A 4FCIA 1TBJA 4Q3TA 5EFJD 4CEVA 4RHJA 5HJ9A 4RHLA 2VQJA 1WOGA 1C3SA 3DJ8A 5LI3A 1T69A 3GN0A 4QA0A 1GQ6A 5DC7A 3SFHA 4BZ5A 4HZEA 1HQ5A 4IU1A 1D3VA 1PQ3A 1VKGA 5THVA 3ZNSA 1HQXA 5G17A 1HQHA 3LHLA 2GH6A 5G1CA 1WOIA 5G0XA 1CEVA 3MFVA 1P8PA 4RN0A 1TBHA 4Q42A 4Q40A 5D1CA 3SL1A 4BZ8A 5G0GA 3E8QA 5HJAA 1T67A 2VQWG 4FCKA 2VQOA 5RLAA 4IU5A 5EFNA 5EFKB 2A0MA 1RLAA 1P8SA 1P8NA 5ICNB 3E9BA 3F06A 4RHIA 1T4TA 4LY1A 3NIQA 4Q3QA 1P8QA 3MFWA 4Q3UA 3KV2A 4Q3SA 4LXZA 2V5XA 4QA6A 5EENA 4HXQA 4QA4A 3E6VA 4QA5A 4MYKA 3Q9CA 1T64A 4I06A 1ZPEA 3SFFA 5G0JA 5G0IA 1T4RA 5G1AA 3THJA 2VQQA 4Q3VA 2ZAVA 5A2SA 1C3PA 4QA3A 4ZUPA 3Q9EA 4BKXB 5EEMA 4ZUQA 1ZZ0A 3MJLA 3Q9FA 4RLAA 3F80A 4Q3RC 2EF5A 2AEBA 3MMRA 4MYLA 3RQDA 3MZ4A 4IU0A 5D1BA 3EW8A 5BWZA 1P8OA 1ZPGA 4Q3PA 3F0RA 2PLLA 5EFBD 1HQGA 4ZURA 5DC8A 4IXUA 4BZ6A 3MAXA 4QA1A 2VCGA 5EEIA 5EEFA 5EFGA 1P8RA 4G3HA 5G0YA 2VQVA 3MENA 4DZ4A 5G3WA 5DC6A 5EF7A 3F07A 4IXVA 4QA2A 4BZ7A 4QA7A 3M1RA 5EFHA 1ZZ1A 3NIOA 4GSZA 2VQMA 3THHA 4BZ9A 5EEKA 1P8MA 4IU4A 3SJTA 3EZTA 4ZUOA 5IX0A 1T5GA 2EF4A 2PHAA 3PZLA 3NIPA 1HQFA 3TH7A 1R1OA
chains in the Genus database with same CATH topology
3C0ZA 5EF8A 4A69A 5G1BA 4ZUNA 4RN1A 5G10A 3EWFA 5D1DA 5THTA 3MZ3A 3EZPA 5G13A 5JI5A 3Q9BA 1C3RA 3C0YA 5G12A 1W22A 5THSA 5DC5A 3C10A 2V5WA 5FCWA 3MZ7A 3ZNRA 5THUA 5IWGA 4ZUMA 4CQFA 1ZZ3A 5FUEA 4RN2A 5G0HA 4CBTA 4CBYA 5G11A 3MZ6A 5EFJD 2VQJA 5LI3A 1C3SA 1T69A 3SFHA 4QA0A 5DC7A 4BZ5A 1VKGA 5THVA 3ZNSA 5G17A 5G1CA 2GH6A 5D1CA 4RN0A 4BZ8A 5G0GA 1T67A 2VQWG 2VQOA 5EFNA 5EFKB 5ICNB 3F06A 4LY1A 4LXZA 2V5XA 4QA6A 5EENA 4QA4A 4QA5A 3Q9CA 1T64A 3SFFA 5G0JA 5G0IA 5G1AA 2VQQA 5A2SA 1C3PA 4QA3A 4ZUPA 3Q9EA 4BKXB 5EEMA 4ZUQA 1ZZ0A 3Q9FA 3RQDA 3MZ4A 5D1BA 3EW8A 5BWZA 3F0RA 5EFBD 4ZURA 5DC8A 4BZ6A 3MAXA 4QA1A 2VCGA 5EEIA 5EEFA 5EFGA 5G0YA 2VQVA 3MENA 5G3WA 5DC6A 5EF7A 3F07A 4QA2A 4BZ7A 4QA7A 5EFHA 1ZZ1A 2VQMA 4BZ9A 5EEKA 3EZTA 4ZUOA 5IX0A 5G0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C0Z A;  5EF8 A;  4A69 A;  5G1B A;  4ZUN A;  4RN1 A;  5G10 A;  3EWF A;  5D1D A;  5THT A;  3MZ3 A;  3EZP A;  5G13 A;  5JI5 A;  3Q9B A;  1C3R A;  3C0Y A;  5G12 A;  1W22 A;  5THS A;  5DC5 A;  3C10 A;  2V5W A;  5FCW A;  3MZ7 A;  3ZNR A;  5THU A;  5IWG A;  4ZUM A;  4CQF A;  1ZZ3 A;  5FUE A;  4RN2 A;  5G0H A;  4CBT A;  4CBY A;  5G11 A;  3MZ6 A;  5EFJ D;  2VQJ A;  5LI3 A;  1C3S A;  1T69 A;  3SFH A;  4QA0 A;  5DC7 A;  4BZ5 A;  1VKG A;  5THV A;  3ZNS A;  5G17 A;  5G1C A;  2GH6 A;  5D1C A;  4RN0 A;  4BZ8 A;  5G0G A;  1T67 A;  2VQW G;  2VQO A;  5EFN A;  5EFK B;  5ICN B;  3F06 A;  4LY1 A;  4LXZ A;  2V5X A;  4QA6 A;  5EEN A;  4QA4 A;  4QA5 A;  3Q9C A;  1T64 A;  3SFF A;  5G0J A;  5G0I A;  5G1A A;  2VQQ A;  5A2S A;  1C3P A;  4QA3 A;  4ZUP A;  3Q9E A;  4BKX B;  5EEM A;  4ZUQ A;  1ZZ0 A;  3Q9F A;  3RQD A;  3MZ4 A;  5D1B A;  3EW8 A;  5BWZ A;  3F0R A;  5EFB D;  4ZUR A;  5DC8 A;  4BZ6 A;  3MAX A;  4QA1 A;  2VCG A;  5EEI A;  5EEF A;  5EFG A;  5G0Y A;  2VQV A;  3MEN A;  5G3W A;  5DC6 A;  5EF7 A;  3F07 A;  4QA2 A;  4BZ7 A;  4QA7 A;  5EFH A;  1ZZ1 A;  2VQM A;  4BZ9 A;  5EEK A;  3EZT A;  4ZUO A;  5IX0 A;  5G0X A; 
#chains in the Genus database with same CATH topology
 3C0Z A;  5EF8 A;  4A69 A;  1TBL A;  3RLA A;  5G1B A;  4ZUN A;  4RN1 A;  1TA1 A;  3EWF A;  4RHK A;  5D1D A;  5G10 A;  5CEV A;  4RHQ A;  4GWC A;  5THT A;  1WVB A;  3MZ3 A;  4GSV A;  1XFK A;  4IE2 A;  3E6K A;  3SL0 A;  1T4S A;  2RLA A;  3EZP A;  5G13 A;  3THE A;  5JI5 A;  3Q9B A;  1WVA A;  3E8Z A;  1C3R A;  3C0Y A;  4Q41 A;  4MXR A;  2EIV A;  5G12 A;  1GQ7 A;  1W22 A;  5THS A;  1T5F A;  4Q3R A;  5DC5 A;  3C10 A;  4ITY A;  2V5W A;  5FCW A;  2PHO A;  4GSM A;  3MZ7 A;  3ZNR A;  4GWD A;  5THU A;  4HWW A;  4RHM A;  1T4P A;  5IWG A;  4ZUM A;  4MYN A;  3LP7 A;  4CQF A;  1ZZ3 A;  3GMZ A;  5FUE A;  3LP4 A;  3SKK A;  4RN2 A;  5G0H A;  4MYF A;  4CBT A;  2CEV A;  4CBY A;  1WOH A;  3CEV A;  3TF3 A;  5G11 A;  4IE3 A;  3MZ6 A;  4IE1 A;  4FCI A;  1TBJ A;  4Q3T A;  5EFJ D;  4CEV A;  4RHJ A;  5HJ9 A;  4RHL A;  2VQJ A;  1WOG A;  1C3S A;  3DJ8 A;  5LI3 A;  1T69 A;  3GN0 A;  4QA0 A;  1GQ6 A;  5DC7 A;  3SFH A;  4BZ5 A;  4HZE A;  1HQ5 A;  4IU1 A;  1D3V A;  1PQ3 A;  1VKG A;  5THV A;  3ZNS A;  1HQX A;  5G17 A;  1HQH A;  3LHL A;  2GH6 A;  5G1C A;  1WOI A;  5G0X A;  1CEV A;  3MFV A;  1P8P A;  4RN0 A;  1TBH A;  4Q42 A;  4Q40 A;  5D1C A;  3SL1 A;  4BZ8 A;  5G0G A;  3E8Q A;  5HJA A;  1T67 A;  2VQW G;  4FCK A;  2VQO A;  5RLA A;  4IU5 A;  5EFN A;  5EFK B;  2A0M A;  1RLA A;  1P8S A;  1P8N A;  5ICN B;  3E9B A;  3F06 A;  4RHI A;  1T4T A;  4LY1 A;  3NIQ A;  4Q3Q A;  1P8Q A;  3MFW A;  4Q3U A;  3KV2 A;  4Q3S A;  4LXZ A;  2V5X A;  4QA6 A;  5EEN A;  4HXQ A;  4QA4 A;  3E6V A;  4QA5 A;  4MYK A;  3Q9C A;  1T64 A;  4I06 A;  1ZPE A;  3SFF A;  5G0J A;  5G0I A;  1T4R A;  5G1A A;  3THJ A;  2VQQ A;  4Q3V A;  2ZAV A;  5A2S A;  1C3P A;  4QA3 A;  4ZUP A;  3Q9E A;  4BKX B;  5EEM A;  4ZUQ A;  1ZZ0 A;  3MJL A;  3Q9F A;  4RLA A;  3F80 A;  4Q3R C;  2EF5 A;  2AEB A;  3MMR A;  4MYL A;  3RQD A;  3MZ4 A;  4IU0 A;  5D1B A;  3EW8 A;  5BWZ A;  1P8O A;  1ZPG A;  4Q3P A;  3F0R A;  2PLL A;  5EFB D;  1HQG A;  4ZUR A;  5DC8 A;  4IXU A;  4BZ6 A;  3MAX A;  4QA1 A;  2VCG A;  5EEI A;  5EEF A;  5EFG A;  1P8R A;  4G3H A;  5G0Y A;  2VQV A;  3MEN A;  4DZ4 A;  5G3W A;  5DC6 A;  5EF7 A;  3F07 A;  4IXV A;  4QA2 A;  4BZ7 A;  4QA7 A;  3M1R A;  5EFH A;  1ZZ1 A;  3NIO A;  4GSZ A;  2VQM A;  3THH A;  4BZ9 A;  5EEK A;  1P8M A;  4IU4 A;  3SJT A;  3EZT A;  4ZUO A;  5IX0 A;  1T5G A;  2EF4 A;  2PHA A;  3PZL A;  3NIP A;  1HQF A;  3TH7 A;  1R1O A; 
#chains in the Genus database with same CATH homology
 3C0Z A;  5EF8 A;  4A69 A;  5G1B A;  4ZUN A;  4RN1 A;  5G10 A;  3EWF A;  5D1D A;  5THT A;  3MZ3 A;  3EZP A;  5G13 A;  5JI5 A;  3Q9B A;  1C3R A;  3C0Y A;  5G12 A;  1W22 A;  5THS A;  5DC5 A;  3C10 A;  2V5W A;  5FCW A;  3MZ7 A;  3ZNR A;  5THU A;  5IWG A;  4ZUM A;  4CQF A;  1ZZ3 A;  5FUE A;  4RN2 A;  5G0H A;  4CBT A;  4CBY A;  5G11 A;  3MZ6 A;  5EFJ D;  2VQJ A;  5LI3 A;  1C3S A;  1T69 A;  3SFH A;  4QA0 A;  5DC7 A;  4BZ5 A;  1VKG A;  5THV A;  3ZNS A;  5G17 A;  5G1C A;  2GH6 A;  5D1C A;  4RN0 A;  4BZ8 A;  5G0G A;  1T67 A;  2VQW G;  2VQO A;  5EFN A;  5EFK B;  5ICN B;  3F06 A;  4LY1 A;  4LXZ A;  2V5X A;  4QA6 A;  5EEN A;  4QA4 A;  4QA5 A;  3Q9C A;  1T64 A;  3SFF A;  5G0J A;  5G0I A;  5G1A A;  2VQQ A;  5A2S A;  1C3P A;  4QA3 A;  4ZUP A;  3Q9E A;  4BKX B;  5EEM A;  4ZUQ A;  1ZZ0 A;  3Q9F A;  3RQD A;  3MZ4 A;  5D1B A;  3EW8 A;  5BWZ A;  3F0R A;  5EFB D;  4ZUR A;  5DC8 A;  4BZ6 A;  3MAX A;  4QA1 A;  2VCG A;  5EEI A;  5EEF A;  5EFG A;  5G0Y A;  2VQV A;  3MEN A;  5G3W A;  5DC6 A;  5EF7 A;  3F07 A;  4QA2 A;  4BZ7 A;  4QA7 A;  5EFH A;  1ZZ1 A;  2VQM A;  4BZ9 A;  5EEK A;  3EZT A;  4ZUO A;  5IX0 A;  5G0X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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