1CEVA

Arginase from bacillus caldovelox, native structure at ph 5.6
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
299
structure length
299
Chain Sequence
MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 113
structure length 299
sequence length 299
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1cevA00
1HQHA 1WOGA 3E6VA 4I06A 1P8SA 3E8ZA 3THJA 4RHIA 4Q40A 4Q3VA 3GN0A 2PHAA 1CEVA 4IU5A 1ZPEA 2AEBA 3TH7A 1T4PA 1HQ5A 4HWWA 3THEA 3THHA 1RLAA 2EF5A 4IE2A 2PLLA 1P8OA 1T4SA 1T4RA 3M1RA 1HQFA 5HJ9A 4GSZA 4FCKA 2A0MA 3MFVA 3MFWA 3NIOA 1P8MA 4Q3QA 3DJ8A 1WVBA 4CEVA 3MMRA 4MYFA 4Q3SA 4RLAA 3LHLA 4IU4A 3GMZA 1T5FA 1ZPGA 4GSMA 3F80A 4MYKA 2ZAVA 1XFKA 1P8RA 1P8QA 3RLAA 4Q42A 1TBJA 1WOIA 4IE3A 2EIVA 4MXRA 3SKKA 1WVAA 4GWCA 4Q3RA 5RLAA 4ITYA 1T4TA 3NIPA 3TF3A 4HZEA 3LP7A 1GQ7A 3LP4A 3NIQA 4FCIA 4IE1A 1HQGA 1GQ6A 1D3VA 4RHMA 4Q3UA 2RLAA 3CEVA 4Q3TA 4IXVA 3MJLA 4Q41A 4GWDA 1TBLA 2EF4A 1T5GA 1HQXA 4Q3PA 3E6KA 1P8NA 1WOHA 4HXQA 1TBHA 5HJAA 1P8PA 5CEVA 3SL0A 4RHJA 4RHQA 3E9BA 4MYNA 3SJTA 1PQ3A 4DZ4A 2CEVA 2PHOA 3PZLA 4IXUA 4Q3RC 3KV2A 4IU0A 4RHKA 4GSVA 1TA1A 4MYLA 4G3HA 4IU1A 4RHLA 1R1OA 3E8QA 3SL1A
chains in the Genus database with same CATH superfamily
1HQHA 1WOGA 1C3PA 5G0IA 5EF8A 5DC5A 3E6VA 4I06A 5G13A 5EFKB 5EFHA 1P8SA 3E8ZA 5FUEA 3THJA 4RHIA 4Q40A 4Q3VA 3GN0A 2VQVA 2PHAA 1CEVA 4IU5A 1T69A 1ZPEA 2AEBA 5JI5A 5EFBD 2V5WA 3TH7A 5BWZA 4ZUQA 1T4PA 4QA4A 1HQ5A 4A69A 5G17A 4HWWA 5EFGA 3THEA 1T67A 5G0HA 3THHA 1RLAA 2EF5A 4IE2A 5THSA 3ZNRA 2PLLA 1P8OA 5EEKA 4CBYA 2VQWG 3Q9BA 1T4SA 1T4RA 3F0RA 3M1RA 5EEIA 1HQFA 3MZ6A 5HJ9A 4GSZA 2A0MA 4FCKA 3MFVA 5G1AA 5THVA 2VQJA 3MFWA 4BZ6A 5EEMA 3NIOA 1P8MA 3Q9FA 4QA6A 4Q3QA 4BZ9A 3DJ8A 1WVBA 4CEVA 3MMRA 4QA2A 4RN1A 2VQQA 2VQMA 4BZ7A 4MYFA 2VCGA 4Q3SA 4RN0A 4CQFA 4RLAA 4BKXB 3LHLA 5D1CA 4IU4A 5EEFA 3GMZA 3F07A 5A2SA 5DC8A 1T5FA 3RQDA 4QA0A 1ZPGA 1ZZ3A 4GSMA 2GH6A 3EW8A 3F80A 4MYKA 5D1DA 2ZAVA 5EFNA 5G0XA 1W22A 5G3WA 2V5XA 1XFKA 1P8RA 1P8QA 2VQOA 1VKGA 5G0YA 3RLAA 4Q42A 5D1BA 1TBJA 4ZUNA 1WOIA 4IE3A 2EIVA 5FCWA 3MZ3A 1ZZ1A 5G0GA 3Q9EA 4MXRA 3SKKA 5LI3A 1WVAA 4GWCA 4Q3RA 3C10A 5IWGA 3C0ZA 5G1CA 5RLAA 4ITYA 5DC7A 1T4TA 3NIPA 3EZPA 3MAXA 5THUA 3TF3A 4HZEA 3LP7A 1GQ7A 3LP4A 4QA1A 3NIQA 4FCIA 5EFJD 4ZUOA 4IE1A 1HQGA 1GQ6A 1D3VA 4LY1A 3SFHA 4RHMA 4Q3UA 2RLAA 3CEVA 3EWFA 4Q3TA 4RN2A 4IXVA 3MJLA 4Q41A 4GWDA 1TBLA 5G0JA 2EF4A 3EZTA 1T5GA 1HQXA 4QA7A 4Q3PA 3E6KA 5EENA 1P8NA 1WOHA 3MZ7A 4HXQA 4LXZA 1TBHA 3MENA 4QA3A 5HJAA 3MZ4A 1P8PA 3ZNSA 4CBTA 5CEVA 3SL0A 4ZUPA 4RHJA 4RHQA 5G1BA 3E9BA 1ZZ0A 4MYNA 3SFFA 3SJTA 1PQ3A 4DZ4A 1T64A 5EF7A 4ZUMA 1C3SA 2CEVA 2PHOA 4QA5A 5G10A 3PZLA 4IXUA 4Q3RC 4BZ8A 3KV2A 4IU0A 5IX0A 4RHKA 5ICNB 5G11A 4GSVA 5G12A 1TA1A 3C0YA 4MYLA 1C3RA 5THTA 4G3HA 4IU1A 3F06A 5DC6A 4ZURA 4BZ5A 4RHLA 1R1OA 3E8QA 3Q9CA 3SL1A
chains in the Genus database with same CATH topology
1HQHA 1WOGA 3E6VA 4I06A 1P8SA 3E8ZA 3THJA 4RHIA 4Q40A 4Q3VA 3GN0A 2PHAA 1CEVA 4IU5A 1ZPEA 2AEBA 3TH7A 1T4PA 1HQ5A 4HWWA 3THEA 3THHA 1RLAA 2EF5A 4IE2A 2PLLA 1P8OA 1T4SA 1T4RA 3M1RA 1HQFA 5HJ9A 4GSZA 4FCKA 2A0MA 3MFVA 3MFWA 3NIOA 1P8MA 4Q3QA 3DJ8A 1WVBA 4CEVA 3MMRA 4MYFA 4Q3SA 4RLAA 3LHLA 4IU4A 3GMZA 1T5FA 1ZPGA 4GSMA 3F80A 4MYKA 2ZAVA 1XFKA 1P8RA 1P8QA 3RLAA 4Q42A 1TBJA 1WOIA 4IE3A 2EIVA 4MXRA 3SKKA 1WVAA 4GWCA 4Q3RA 5RLAA 4ITYA 1T4TA 3NIPA 3TF3A 4HZEA 3LP7A 1GQ7A 3LP4A 3NIQA 4FCIA 4IE1A 1HQGA 1GQ6A 1D3VA 4RHMA 4Q3UA 2RLAA 3CEVA 4Q3TA 4IXVA 3MJLA 4Q41A 4GWDA 1TBLA 2EF4A 1T5GA 1HQXA 4Q3PA 3E6KA 1P8NA 1WOHA 4HXQA 1TBHA 5HJAA 1P8PA 5CEVA 3SL0A 4RHJA 4RHQA 3E9BA 4MYNA 3SJTA 1PQ3A 4DZ4A 2CEVA 2PHOA 3PZLA 4IXUA 4Q3RC 3KV2A 4IU0A 4RHKA 4GSVA 1TA1A 4MYLA 4G3HA 4IU1A 4RHLA 1R1OA 3E8QA 3SL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HQH A;  1WOG A;  3E6V A;  4I06 A;  1P8S A;  3E8Z A;  3THJ A;  4RHI A;  4Q40 A;  4Q3V A;  3GN0 A;  2PHA A;  1CEV A;  4IU5 A;  1ZPE A;  2AEB A;  3TH7 A;  1T4P A;  1HQ5 A;  4HWW A;  3THE A;  3THH A;  1RLA A;  2EF5 A;  4IE2 A;  2PLL A;  1P8O A;  1T4S A;  1T4R A;  3M1R A;  1HQF A;  5HJ9 A;  4GSZ A;  4FCK A;  2A0M A;  3MFV A;  3MFW A;  3NIO A;  1P8M A;  4Q3Q A;  3DJ8 A;  1WVB A;  4CEV A;  3MMR A;  4MYF A;  4Q3S A;  4RLA A;  3LHL A;  4IU4 A;  3GMZ A;  1T5F A;  1ZPG A;  4GSM A;  3F80 A;  4MYK A;  2ZAV A;  1XFK A;  1P8R A;  1P8Q A;  3RLA A;  4Q42 A;  1TBJ A;  1WOI A;  4IE3 A;  2EIV A;  4MXR A;  3SKK A;  1WVA A;  4GWC A;  4Q3R A;  5RLA A;  4ITY A;  1T4T A;  3NIP A;  3TF3 A;  4HZE A;  3LP7 A;  1GQ7 A;  3LP4 A;  3NIQ A;  4FCI A;  4IE1 A;  1HQG A;  1GQ6 A;  1D3V A;  4RHM A;  4Q3U A;  2RLA A;  3CEV A;  4Q3T A;  4IXV A;  3MJL A;  4Q41 A;  4GWD A;  1TBL A;  2EF4 A;  1T5G A;  1HQX A;  4Q3P A;  3E6K A;  1P8N A;  1WOH A;  4HXQ A;  1TBH A;  5HJA A;  1P8P A;  5CEV A;  3SL0 A;  4RHJ A;  4RHQ A;  3E9B A;  4MYN A;  3SJT A;  1PQ3 A;  4DZ4 A;  2CEV A;  2PHO A;  3PZL A;  4IXU A;  4Q3R C;  3KV2 A;  4IU0 A;  4RHK A;  4GSV A;  1TA1 A;  4MYL A;  4G3H A;  4IU1 A;  4RHL A;  1R1O A;  3E8Q A;  3SL1 A; 
#chains in the Genus database with same CATH topology
 1HQH A;  1WOG A;  1C3P A;  5G0I A;  5EF8 A;  5DC5 A;  3E6V A;  4I06 A;  5G13 A;  5EFK B;  5EFH A;  1P8S A;  3E8Z A;  5FUE A;  3THJ A;  4RHI A;  4Q40 A;  4Q3V A;  3GN0 A;  2VQV A;  2PHA A;  1CEV A;  4IU5 A;  1T69 A;  1ZPE A;  2AEB A;  5JI5 A;  5EFB D;  2V5W A;  3TH7 A;  5BWZ A;  4ZUQ A;  1T4P A;  4QA4 A;  1HQ5 A;  4A69 A;  5G17 A;  4HWW A;  5EFG A;  3THE A;  1T67 A;  5G0H A;  3THH A;  1RLA A;  2EF5 A;  4IE2 A;  5THS A;  3ZNR A;  2PLL A;  1P8O A;  5EEK A;  4CBY A;  2VQW G;  3Q9B A;  1T4S A;  1T4R A;  3F0R A;  3M1R A;  5EEI A;  1HQF A;  3MZ6 A;  5HJ9 A;  4GSZ A;  2A0M A;  4FCK A;  3MFV A;  5G1A A;  5THV A;  2VQJ A;  3MFW A;  4BZ6 A;  5EEM A;  3NIO A;  1P8M A;  3Q9F A;  4QA6 A;  4Q3Q A;  4BZ9 A;  3DJ8 A;  1WVB A;  4CEV A;  3MMR A;  4QA2 A;  4RN1 A;  2VQQ A;  2VQM A;  4BZ7 A;  4MYF A;  2VCG A;  4Q3S A;  4RN0 A;  4CQF A;  4RLA A;  4BKX B;  3LHL A;  5D1C A;  4IU4 A;  5EEF A;  3GMZ A;  3F07 A;  5A2S A;  5DC8 A;  1T5F A;  3RQD A;  4QA0 A;  1ZPG A;  1ZZ3 A;  4GSM A;  2GH6 A;  3EW8 A;  3F80 A;  4MYK A;  5D1D A;  2ZAV A;  5EFN A;  5G0X A;  1W22 A;  5G3W A;  2V5X A;  1XFK A;  1P8R A;  1P8Q A;  2VQO A;  1VKG A;  5G0Y A;  3RLA A;  4Q42 A;  5D1B A;  1TBJ A;  4ZUN A;  1WOI A;  4IE3 A;  2EIV A;  5FCW A;  3MZ3 A;  1ZZ1 A;  5G0G A;  3Q9E A;  4MXR A;  3SKK A;  5LI3 A;  1WVA A;  4GWC A;  4Q3R A;  3C10 A;  5IWG A;  3C0Z A;  5G1C A;  5RLA A;  4ITY A;  5DC7 A;  1T4T A;  3NIP A;  3EZP A;  3MAX A;  5THU A;  3TF3 A;  4HZE A;  3LP7 A;  1GQ7 A;  3LP4 A;  4QA1 A;  3NIQ A;  4FCI A;  5EFJ D;  4ZUO A;  4IE1 A;  1HQG A;  1GQ6 A;  1D3V A;  4LY1 A;  3SFH A;  4RHM A;  4Q3U A;  2RLA A;  3CEV A;  3EWF A;  4Q3T A;  4RN2 A;  4IXV A;  3MJL A;  4Q41 A;  4GWD A;  1TBL A;  5G0J A;  2EF4 A;  3EZT A;  1T5G A;  1HQX A;  4QA7 A;  4Q3P A;  3E6K A;  5EEN A;  1P8N A;  1WOH A;  3MZ7 A;  4HXQ A;  4LXZ A;  1TBH A;  3MEN A;  4QA3 A;  5HJA A;  3MZ4 A;  1P8P A;  3ZNS A;  4CBT A;  5CEV A;  3SL0 A;  4ZUP A;  4RHJ A;  4RHQ A;  5G1B A;  3E9B A;  1ZZ0 A;  4MYN A;  3SFF A;  3SJT A;  1PQ3 A;  4DZ4 A;  1T64 A;  5EF7 A;  4ZUM A;  1C3S A;  2CEV A;  2PHO A;  4QA5 A;  5G10 A;  3PZL A;  4IXU A;  4Q3R C;  4BZ8 A;  3KV2 A;  4IU0 A;  5IX0 A;  4RHK A;  5ICN B;  5G11 A;  4GSV A;  5G12 A;  1TA1 A;  3C0Y A;  4MYL A;  1C3R A;  5THT A;  4G3H A;  4IU1 A;  3F06 A;  5DC6 A;  4ZUR A;  4BZ5 A;  4RHL A;  1R1O A;  3E8Q A;  3Q9C A;  3SL1 A; 
#chains in the Genus database with same CATH homology
 1HQH A;  1WOG A;  3E6V A;  4I06 A;  1P8S A;  3E8Z A;  3THJ A;  4RHI A;  4Q40 A;  4Q3V A;  3GN0 A;  2PHA A;  1CEV A;  4IU5 A;  1ZPE A;  2AEB A;  3TH7 A;  1T4P A;  1HQ5 A;  4HWW A;  3THE A;  3THH A;  1RLA A;  2EF5 A;  4IE2 A;  2PLL A;  1P8O A;  1T4S A;  1T4R A;  3M1R A;  1HQF A;  5HJ9 A;  4GSZ A;  4FCK A;  2A0M A;  3MFV A;  3MFW A;  3NIO A;  1P8M A;  4Q3Q A;  3DJ8 A;  1WVB A;  4CEV A;  3MMR A;  4MYF A;  4Q3S A;  4RLA A;  3LHL A;  4IU4 A;  3GMZ A;  1T5F A;  1ZPG A;  4GSM A;  3F80 A;  4MYK A;  2ZAV A;  1XFK A;  1P8R A;  1P8Q A;  3RLA A;  4Q42 A;  1TBJ A;  1WOI A;  4IE3 A;  2EIV A;  4MXR A;  3SKK A;  1WVA A;  4GWC A;  4Q3R A;  5RLA A;  4ITY A;  1T4T A;  3NIP A;  3TF3 A;  4HZE A;  3LP7 A;  1GQ7 A;  3LP4 A;  3NIQ A;  4FCI A;  4IE1 A;  1HQG A;  1GQ6 A;  1D3V A;  4RHM A;  4Q3U A;  2RLA A;  3CEV A;  4Q3T A;  4IXV A;  3MJL A;  4Q41 A;  4GWD A;  1TBL A;  2EF4 A;  1T5G A;  1HQX A;  4Q3P A;  3E6K A;  1P8N A;  1WOH A;  4HXQ A;  1TBH A;  5HJA A;  1P8P A;  5CEV A;  3SL0 A;  4RHJ A;  4RHQ A;  3E9B A;  4MYN A;  3SJT A;  1PQ3 A;  4DZ4 A;  2CEV A;  2PHO A;  3PZL A;  4IXU A;  4Q3R C;  3KV2 A;  4IU0 A;  4RHK A;  4GSV A;  1TA1 A;  4MYL A;  4G3H A;  4IU1 A;  4RHL A;  1R1O A;  3E8Q A;  3SL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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