1HQHA

Crystal structure of the binuclear manganese metalloenzyme arginase complexed with nor-n-hydroxy-l-arginine
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords ARGINASE 1
total genus 106
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2000-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1hqhA00
3DJ8A 3LHLA 4MYKA 2EF5A 4FCKA 2EF4A 3NIPA 4Q3RC 4IE1A 4RHKA 1P8MA 1T5FA 3NIOA 5HJ9A 1WVAA 2PHAA 4IE2A 2RLAA 4MYFA 1HQ5A 4RHMA 3E8QA 1GQ6A 4G3HA 4IXVA 4MYLA 3TH7A 3SL0A 1WOHA 1HQXA 2A0MA 3E8ZA 1WOIA 3SJTA 4Q41A 1P8RA 4HZEA 4CEVA 1GQ7A 3GN0A 4IU5A 4GSZA 4I06A 1TBHA 4IE3A 1T4RA 5CEVA 1T5GA 3E6VA 4IXUA 1ZPEA 3NIQA 3LP7A 4Q3UA 4RLAA 2ZAVA 4FCIA 1P8OA 4GWCA 4RHJA 4Q40A 3KV2A 2PHOA 3CEVA 1P8QA 4IU0A 3RLAA 3MFVA 1WVBA 4ITYA 1D3VA 2AEBA 3THJA 1R1OA 1P8SA 3GMZA 4RHIA 3MJLA 4Q3PA 1WOGA 1XFKA 3F80A 4HWWA 3MMRA 1RLAA 4RHLA 5RLAA 4Q3TA 4Q3SA 3THEA 4IU1A 3E9BA 3M1RA 2PLLA 4GSMA 4Q3RA 1PQ3A 4DZ4A 4MYNA 3SL1A 3MFWA 1TBJA 1HQGA 4Q3VA 3TF3A 1TBLA 2CEVA 4Q3QA 4RHQA 4GWDA 3LP4A 4Q42A 3THHA 1TA1A 2EIVA 1T4SA 4GSVA 3PZLA 1CEVA 1HQFA 1P8NA 5HJAA 4HXQA 1T4PA 1ZPGA 3SKKA 1HQHA 3E6KA 1T4TA 4MXRA 1P8PA 4IU4A
chains in the Genus database with same CATH superfamily
5G0HA 3DJ8A 4BZ6A 5EEKA 3LHLA 3MZ6A 4MYKA 5THUA 2EF5A 3RQDA 3SFFA 4FCKA 5G0JA 2EF4A 1ZZ0A 3EZTA 3NIPA 4IE1A 4Q3RC 1P8MA 2VCGA 1T5FA 3NIOA 3Q9BA 1WVAA 4QA1A 2PHAA 4RHKA 5HJ9A 1ZZ1A 5EENA 2VQQA 3ZNSA 4IE2A 4BZ9A 2RLAA 5G10A 4MYFA 5G17A 1HQ5A 3F0RA 4QA4A 3E8QA 4QA6A 4LY1A 2V5XA 4RHMA 4BZ8A 1GQ6A 4BZ5A 4G3HA 5JI5A 4IXVA 4MYLA 5G1BA 1C3SA 3TH7A 3SL0A 1WOHA 1HQXA 1W22A 5DC8A 2A0MA 5FUEA 5G1AA 3E8ZA 1WOIA 3SJTA 4BZ7A 4Q41A 1P8RA 4HZEA 5EFJD 4BKXB 4CEVA 5A2SA 1GQ7A 3GN0A 4IU5A 4GSZA 4ZUPA 5G11A 4I06A 3SFHA 5LI3A 5EFBD 1TBHA 5D1BA 4QA2A 1C3RA 5EF8A 2VQWG 3EZPA 4IE3A 1T4RA 5IX0A 5CEVA 1T5GA 5G1CA 3E6VA 4IXUA 4RN1A 1ZPEA 5D1DA 3NIQA 4CBTA 3LP7A 5EFHA 4Q3UA 4RLAA 2ZAVA 4FCIA 1C3PA 4ZUNA 5G0XA 1P8OA 4GWCA 4RHJA 4Q40A 3CEVA 2PHOA 3KV2A 5D1CA 1P8QA 4IU0A 3RLAA 3MFVA 4QA5A 5G3WA 4ZUOA 3Q9CA 1WVBA 4ITYA 1D3VA 2AEBA 4RN0A 3THJA 1ZZ3A 1R1OA 1P8SA 5G0IA 3MZ4A 5BWZA 3GMZA 4RHIA 4CBYA 5G13A 5ICNB 3MJLA 4Q3PA 4CQFA 1WOGA 1XFKA 4RN2A 3F06A 4ZUQA 3F80A 4HWWA 3MMRA 1RLAA 2VQMA 3Q9EA 4RHLA 5RLAA 2VQJA 4Q3TA 4Q3SA 4ZUMA 5DC5A 5G0YA 5EFKB 3THEA 2GH6A 3Q9FA 3E9BA 4IU1A 5IWGA 4QA7A 5G12A 3M1RA 2PLLA 4GSMA 4Q3RA 5DC7A 1PQ3A 4DZ4A 4MYNA 3SL1A 1T67A 4QA0A 3MFWA 1TBJA 1HQGA 4QA3A 5THVA 4Q3VA 5EF7A 4ZURA 3TF3A 1TBLA 2CEVA 4Q3QA 3MZ3A 5THTA 4RHQA 4GWDA 3LP4A 3ZNRA 4Q42A 3C0ZA 5EEFA 5G0GA 5DC6A 3MENA 3THHA 1TA1A 5EFNA 3MAXA 2EIVA 1T4SA 3MZ7A 1VKGA 4GSVA 1T69A 1T64A 3EW8A 3PZLA 1CEVA 3C0YA 1HQFA 2V5WA 5THSA 5EEIA 1P8NA 2VQVA 5HJAA 4HXQA 4LXZA 1T4PA 1ZPGA 3C10A 3SKKA 4A69A 1HQHA 5FCWA 3E6KA 1T4TA 4MXRA 5EFGA 1P8PA 3F07A 5EEMA 2VQOA 3EWFA 4IU4A
chains in the Genus database with same CATH topology
3DJ8A 3LHLA 4MYKA 2EF5A 4FCKA 2EF4A 3NIPA 4Q3RC 4IE1A 4RHKA 1P8MA 1T5FA 3NIOA 5HJ9A 1WVAA 2PHAA 4IE2A 2RLAA 4MYFA 1HQ5A 4RHMA 3E8QA 1GQ6A 4G3HA 4IXVA 4MYLA 3TH7A 3SL0A 1WOHA 1HQXA 2A0MA 3E8ZA 1WOIA 3SJTA 4Q41A 1P8RA 4HZEA 4CEVA 1GQ7A 3GN0A 4IU5A 4GSZA 4I06A 1TBHA 4IE3A 1T4RA 5CEVA 1T5GA 3E6VA 4IXUA 1ZPEA 3NIQA 3LP7A 4Q3UA 4RLAA 2ZAVA 4FCIA 1P8OA 4GWCA 4RHJA 4Q40A 3KV2A 2PHOA 3CEVA 1P8QA 4IU0A 3RLAA 3MFVA 1WVBA 4ITYA 1D3VA 2AEBA 3THJA 1R1OA 1P8SA 3GMZA 4RHIA 3MJLA 4Q3PA 1WOGA 1XFKA 3F80A 4HWWA 3MMRA 1RLAA 4RHLA 5RLAA 4Q3TA 4Q3SA 3THEA 4IU1A 3E9BA 3M1RA 2PLLA 4GSMA 4Q3RA 1PQ3A 4DZ4A 4MYNA 3SL1A 3MFWA 1TBJA 1HQGA 4Q3VA 3TF3A 1TBLA 2CEVA 4Q3QA 4RHQA 4GWDA 3LP4A 4Q42A 3THHA 1TA1A 2EIVA 1T4SA 4GSVA 3PZLA 1CEVA 1HQFA 1P8NA 5HJAA 4HXQA 1T4PA 1ZPGA 3SKKA 1HQHA 3E6KA 1T4TA 4MXRA 1P8PA 4IU4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DJ8 A;  3LHL A;  4MYK A;  2EF5 A;  4FCK A;  2EF4 A;  3NIP A;  4Q3R C;  4IE1 A;  4RHK A;  1P8M A;  1T5F A;  3NIO A;  5HJ9 A;  1WVA A;  2PHA A;  4IE2 A;  2RLA A;  4MYF A;  1HQ5 A;  4RHM A;  3E8Q A;  1GQ6 A;  4G3H A;  4IXV A;  4MYL A;  3TH7 A;  3SL0 A;  1WOH A;  1HQX A;  2A0M A;  3E8Z A;  1WOI A;  3SJT A;  4Q41 A;  1P8R A;  4HZE A;  4CEV A;  1GQ7 A;  3GN0 A;  4IU5 A;  4GSZ A;  4I06 A;  1TBH A;  4IE3 A;  1T4R A;  5CEV A;  1T5G A;  3E6V A;  4IXU A;  1ZPE A;  3NIQ A;  3LP7 A;  4Q3U A;  4RLA A;  2ZAV A;  4FCI A;  1P8O A;  4GWC A;  4RHJ A;  4Q40 A;  3KV2 A;  2PHO A;  3CEV A;  1P8Q A;  4IU0 A;  3RLA A;  3MFV A;  1WVB A;  4ITY A;  1D3V A;  2AEB A;  3THJ A;  1R1O A;  1P8S A;  3GMZ A;  4RHI A;  3MJL A;  4Q3P A;  1WOG A;  1XFK A;  3F80 A;  4HWW A;  3MMR A;  1RLA A;  4RHL A;  5RLA A;  4Q3T A;  4Q3S A;  3THE A;  4IU1 A;  3E9B A;  3M1R A;  2PLL A;  4GSM A;  4Q3R A;  1PQ3 A;  4DZ4 A;  4MYN A;  3SL1 A;  3MFW A;  1TBJ A;  1HQG A;  4Q3V A;  3TF3 A;  1TBL A;  2CEV A;  4Q3Q A;  4RHQ A;  4GWD A;  3LP4 A;  4Q42 A;  3THH A;  1TA1 A;  2EIV A;  1T4S A;  4GSV A;  3PZL A;  1CEV A;  1HQF A;  1P8N A;  5HJA A;  4HXQ A;  1T4P A;  1ZPG A;  3SKK A;  1HQH A;  3E6K A;  1T4T A;  4MXR A;  1P8P A;  4IU4 A; 
#chains in the Genus database with same CATH topology
 5G0H A;  3DJ8 A;  4BZ6 A;  5EEK A;  3LHL A;  3MZ6 A;  4MYK A;  5THU A;  2EF5 A;  3RQD A;  3SFF A;  4FCK A;  5G0J A;  2EF4 A;  1ZZ0 A;  3EZT A;  3NIP A;  4IE1 A;  4Q3R C;  1P8M A;  2VCG A;  1T5F A;  3NIO A;  3Q9B A;  1WVA A;  4QA1 A;  2PHA A;  4RHK A;  5HJ9 A;  1ZZ1 A;  5EEN A;  2VQQ A;  3ZNS A;  4IE2 A;  4BZ9 A;  2RLA A;  5G10 A;  4MYF A;  5G17 A;  1HQ5 A;  3F0R A;  4QA4 A;  3E8Q A;  4QA6 A;  4LY1 A;  2V5X A;  4RHM A;  4BZ8 A;  1GQ6 A;  4BZ5 A;  4G3H A;  5JI5 A;  4IXV A;  4MYL A;  5G1B A;  1C3S A;  3TH7 A;  3SL0 A;  1WOH A;  1HQX A;  1W22 A;  5DC8 A;  2A0M A;  5FUE A;  5G1A A;  3E8Z A;  1WOI A;  3SJT A;  4BZ7 A;  4Q41 A;  1P8R A;  4HZE A;  5EFJ D;  4BKX B;  4CEV A;  5A2S A;  1GQ7 A;  3GN0 A;  4IU5 A;  4GSZ A;  4ZUP A;  5G11 A;  4I06 A;  3SFH A;  5LI3 A;  5EFB D;  1TBH A;  5D1B A;  4QA2 A;  1C3R A;  5EF8 A;  2VQW G;  3EZP A;  4IE3 A;  1T4R A;  5IX0 A;  5CEV A;  1T5G A;  5G1C A;  3E6V A;  4IXU A;  4RN1 A;  1ZPE A;  5D1D A;  3NIQ A;  4CBT A;  3LP7 A;  5EFH A;  4Q3U A;  4RLA A;  2ZAV A;  4FCI A;  1C3P A;  4ZUN A;  5G0X A;  1P8O A;  4GWC A;  4RHJ A;  4Q40 A;  3CEV A;  2PHO A;  3KV2 A;  5D1C A;  1P8Q A;  4IU0 A;  3RLA A;  3MFV A;  4QA5 A;  5G3W A;  4ZUO A;  3Q9C A;  1WVB A;  4ITY A;  1D3V A;  2AEB A;  4RN0 A;  3THJ A;  1ZZ3 A;  1R1O A;  1P8S A;  5G0I A;  3MZ4 A;  5BWZ A;  3GMZ A;  4RHI A;  4CBY A;  5G13 A;  5ICN B;  3MJL A;  4Q3P A;  4CQF A;  1WOG A;  1XFK A;  4RN2 A;  3F06 A;  4ZUQ A;  3F80 A;  4HWW A;  3MMR A;  1RLA A;  2VQM A;  3Q9E A;  4RHL A;  5RLA A;  2VQJ A;  4Q3T A;  4Q3S A;  4ZUM A;  5DC5 A;  5G0Y A;  5EFK B;  3THE A;  2GH6 A;  3Q9F A;  3E9B A;  4IU1 A;  5IWG A;  4QA7 A;  5G12 A;  3M1R A;  2PLL A;  4GSM A;  4Q3R A;  5DC7 A;  1PQ3 A;  4DZ4 A;  4MYN A;  3SL1 A;  1T67 A;  4QA0 A;  3MFW A;  1TBJ A;  1HQG A;  4QA3 A;  5THV A;  4Q3V A;  5EF7 A;  4ZUR A;  3TF3 A;  1TBL A;  2CEV A;  4Q3Q A;  3MZ3 A;  5THT A;  4RHQ A;  4GWD A;  3LP4 A;  3ZNR A;  4Q42 A;  3C0Z A;  5EEF A;  5G0G A;  5DC6 A;  3MEN A;  3THH A;  1TA1 A;  5EFN A;  3MAX A;  2EIV A;  1T4S A;  3MZ7 A;  1VKG A;  4GSV A;  1T69 A;  1T64 A;  3EW8 A;  3PZL A;  1CEV A;  3C0Y A;  1HQF A;  2V5W A;  5THS A;  5EEI A;  1P8N A;  2VQV A;  5HJA A;  4HXQ A;  4LXZ A;  1T4P A;  1ZPG A;  3C10 A;  3SKK A;  4A69 A;  1HQH A;  5FCW A;  3E6K A;  1T4T A;  4MXR A;  5EFG A;  1P8P A;  3F07 A;  5EEM A;  2VQO A;  3EWF A;  4IU4 A; 
#chains in the Genus database with same CATH homology
 3DJ8 A;  3LHL A;  4MYK A;  2EF5 A;  4FCK A;  2EF4 A;  3NIP A;  4Q3R C;  4IE1 A;  4RHK A;  1P8M A;  1T5F A;  3NIO A;  5HJ9 A;  1WVA A;  2PHA A;  4IE2 A;  2RLA A;  4MYF A;  1HQ5 A;  4RHM A;  3E8Q A;  1GQ6 A;  4G3H A;  4IXV A;  4MYL A;  3TH7 A;  3SL0 A;  1WOH A;  1HQX A;  2A0M A;  3E8Z A;  1WOI A;  3SJT A;  4Q41 A;  1P8R A;  4HZE A;  4CEV A;  1GQ7 A;  3GN0 A;  4IU5 A;  4GSZ A;  4I06 A;  1TBH A;  4IE3 A;  1T4R A;  5CEV A;  1T5G A;  3E6V A;  4IXU A;  1ZPE A;  3NIQ A;  3LP7 A;  4Q3U A;  4RLA A;  2ZAV A;  4FCI A;  1P8O A;  4GWC A;  4RHJ A;  4Q40 A;  3KV2 A;  2PHO A;  3CEV A;  1P8Q A;  4IU0 A;  3RLA A;  3MFV A;  1WVB A;  4ITY A;  1D3V A;  2AEB A;  3THJ A;  1R1O A;  1P8S A;  3GMZ A;  4RHI A;  3MJL A;  4Q3P A;  1WOG A;  1XFK A;  3F80 A;  4HWW A;  3MMR A;  1RLA A;  4RHL A;  5RLA A;  4Q3T A;  4Q3S A;  3THE A;  4IU1 A;  3E9B A;  3M1R A;  2PLL A;  4GSM A;  4Q3R A;  1PQ3 A;  4DZ4 A;  4MYN A;  3SL1 A;  3MFW A;  1TBJ A;  1HQG A;  4Q3V A;  3TF3 A;  1TBL A;  2CEV A;  4Q3Q A;  4RHQ A;  4GWD A;  3LP4 A;  4Q42 A;  3THH A;  1TA1 A;  2EIV A;  1T4S A;  4GSV A;  3PZL A;  1CEV A;  1HQF A;  1P8N A;  5HJA A;  4HXQ A;  1T4P A;  1ZPG A;  3SKK A;  1HQH A;  3E6K A;  1T4T A;  4MXR A;  1P8P A;  4IU4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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