1P8MA

Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase i.
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
314
structure length
314
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTEINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase 1
total genus 114
structure length 314
sequence length 314
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2003-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1p8mA00
4RHQA 2EF4A 4HZEA 2A0MA 4MXRA 3THEA 3E6VA 4FCKA 1CEVA 1T5GA 5HJ9A 4CEVA 1GQ6A 2EIVA 1P8RA 1P8QA 3SKKA 1P8PA 4IU0A 3PZLA 1HQXA 1HQGA 2EF5A 1RLAA 2PHAA 4RHJA 1TA1A 2AEBA 4GWDA 1HQHA 4DZ4A 1R1OA 3LHLA 4IXVA 1TBJA 4Q3TA 4Q41A 1ZPGA 1T4TA 4RLAA 4Q3RC 3LP7A 2CEVA 2PHOA 2RLAA 4Q42A 3MFVA 4MYKA 1WVAA 4I06A 3E6KA 4ITYA 4GSZA 2ZAVA 3LP4A 4RHMA 5HJAA 1P8SA 3SJTA 3NIOA 4MYNA 5RLAA 1T4RA 4Q3SA 3NIPA 1T4SA 4IU5A 3CEVA 1D3VA 4Q3QA 3E8QA 1P8NA 4IU1A 4IE3A 4GSMA 3M1RA 1WOIA 3SL0A 3TF3A 2PLLA 4HWWA 3RLAA 1TBLA 5CEVA 3GMZA 1T4PA 4Q3VA 3SL1A 3MJLA 3KV2A 4IE2A 1WOGA 3MMRA 3NIQA 3MFWA 1P8OA 4FCIA 3DJ8A 4RHIA 3THHA 1ZPEA 3F80A 4MYLA 4IU4A 4G3HA 3GN0A 4HXQA 4IE1A 4Q3PA 4IXUA 4Q40A 1XFKA 4Q3RA 4GSVA 3E9BA 3TH7A 1HQFA 3E8ZA 4Q3UA 4MYFA 1P8MA 4GWCA 4RHKA 1TBHA 1GQ7A 1HQ5A 1T5FA 4RHLA 3THJA 1WVBA 1PQ3A 1WOHA
chains in the Genus database with same CATH superfamily
3C0YA 4QA5A 2EF4A 4RHQA 4HZEA 2A0MA 4MXRA 5G1AA 5G0IA 3THEA 3E6VA 4FCKA 1CEVA 1T5GA 4QA1A 5HJ9A 5G1BA 4CBYA 3F0RA 1GQ6A 2EIVA 5D1BA 5D1CA 4BKXB 1P8RA 1P8QA 4BZ8A 1ZZ0A 3SKKA 1P8PA 4IU0A 3PZLA 4LY1A 2VQWG 5G0HA 4ZUNA 1HQXA 1HQGA 4RN1A 2EF5A 5G10A 3EWFA 4BZ6A 1RLAA 2PHAA 5G0GA 3MAXA 4RHJA 3SFHA 5EENA 1TA1A 5EFHA 2AEBA 4GWDA 1HQHA 4DZ4A 1R1OA 1T64A 5EEMA 2VQJA 3LHLA 2GH6A 3Q9BA 4IXVA 1TBJA 5FUEA 5LI3A 5IWGA 5THVA 4Q3TA 4Q41A 5G0YA 5EEFA 1ZPGA 1T4TA 4RLAA 4Q3RC 3LP7A 5DC5A 5EFGA 4CEVA 4BZ9A 3ZNRA 2CEVA 2PHOA 2RLAA 5DC6A 5IX0A 4Q42A 5THUA 3MFVA 3MZ7A 4QA3A 5DC7A 4MYKA 4BZ5A 1WVAA 4I06A 3E6KA 3EZTA 4ITYA 5EFNA 3Q9EA 2VQMA 4GSZA 2ZAVA 4A69A 4CBTA 3LP4A 4RHMA 3C0ZA 5HJAA 1P8SA 3MZ6A 1T67A 1VKGA 3SJTA 3NIOA 3F06A 4MYNA 5RLAA 1T4RA 5THTA 4Q3SA 3NIPA 1T4SA 2V5WA 4IU5A 3CEVA 5THSA 1D3VA 4Q3QA 5G3WA 4CQFA 4ZUQA 2VCGA 4QA0A 3E8QA 1P8NA 5G1CA 4IU1A 4ZUMA 3ZNSA 5EFBD 2VQVA 4IE3A 1C3SA 4GSMA 5FCWA 5EFKB 3M1RA 1WOIA 3SL0A 4BZ7A 3TF3A 2PLLA 4HWWA 3RLAA 4ZUPA 1C3PA 1ZZ1A 4QA6A 1TBLA 5G0JA 2V5XA 3GMZA 5CEVA 1T4PA 4Q3VA 5EF8A 3SL1A 3MJLA 5A2SA 3KV2A 4IE2A 1WOGA 3MMRA 3NIQA 1P8OA 3MFWA 3DJ8A 4FCIA 4RHIA 5DC8A 3THHA 1ZPEA 3F80A 3EZPA 4MYLA 4IU4A 5D1DA 3Q9CA 4G3HA 3SFFA 3GN0A 3RQDA 3MENA 4HXQA 4RN0A 4IE1A 4Q3PA 4IXUA 5EF7A 5EEKA 5G12A 5BWZA 4Q40A 1XFKA 4Q3RA 4GSVA 3Q9FA 3F07A 4LXZA 1T69A 3E9BA 4QA2A 5G13A 3TH7A 4ZURA 1HQFA 4RN2A 2VQOA 3E8ZA 5EEIA 4Q3UA 3MZ4A 1P8MA 4MYFA 4GWCA 4RHKA 4ZUOA 3C10A 2VQQA 1TBHA 1GQ7A 5JI5A 3MZ3A 5EFJD 1HQ5A 5G0XA 1T5FA 4RHLA 3THJA 1WVBA 1W22A 1PQ3A 4QA7A 1C3RA 5G11A 5ICNB 1ZZ3A 4QA4A 1WOHA 3EW8A 5G17A
chains in the Genus database with same CATH topology
4RHQA 2EF4A 4HZEA 2A0MA 4MXRA 3THEA 3E6VA 4FCKA 1CEVA 1T5GA 5HJ9A 4CEVA 1GQ6A 2EIVA 1P8RA 1P8QA 3SKKA 1P8PA 4IU0A 3PZLA 1HQXA 1HQGA 2EF5A 1RLAA 2PHAA 4RHJA 1TA1A 2AEBA 4GWDA 1HQHA 4DZ4A 1R1OA 3LHLA 4IXVA 1TBJA 4Q3TA 4Q41A 1ZPGA 1T4TA 4RLAA 4Q3RC 3LP7A 2CEVA 2PHOA 2RLAA 4Q42A 3MFVA 4MYKA 1WVAA 4I06A 3E6KA 4ITYA 4GSZA 2ZAVA 3LP4A 4RHMA 5HJAA 1P8SA 3SJTA 3NIOA 4MYNA 5RLAA 1T4RA 4Q3SA 3NIPA 1T4SA 4IU5A 3CEVA 1D3VA 4Q3QA 3E8QA 1P8NA 4IU1A 4IE3A 4GSMA 3M1RA 1WOIA 3SL0A 3TF3A 2PLLA 4HWWA 3RLAA 1TBLA 5CEVA 3GMZA 1T4PA 4Q3VA 3SL1A 3MJLA 3KV2A 4IE2A 1WOGA 3MMRA 3NIQA 3MFWA 1P8OA 4FCIA 3DJ8A 4RHIA 3THHA 1ZPEA 3F80A 4MYLA 4IU4A 4G3HA 3GN0A 4HXQA 4IE1A 4Q3PA 4IXUA 4Q40A 1XFKA 4Q3RA 4GSVA 3E9BA 3TH7A 1HQFA 3E8ZA 4Q3UA 4MYFA 1P8MA 4GWCA 4RHKA 1TBHA 1GQ7A 1HQ5A 1T5FA 4RHLA 3THJA 1WVBA 1PQ3A 1WOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RHQ A;  2EF4 A;  4HZE A;  2A0M A;  4MXR A;  3THE A;  3E6V A;  4FCK A;  1CEV A;  1T5G A;  5HJ9 A;  4CEV A;  1GQ6 A;  2EIV A;  1P8R A;  1P8Q A;  3SKK A;  1P8P A;  4IU0 A;  3PZL A;  1HQX A;  1HQG A;  2EF5 A;  1RLA A;  2PHA A;  4RHJ A;  1TA1 A;  2AEB A;  4GWD A;  1HQH A;  4DZ4 A;  1R1O A;  3LHL A;  4IXV A;  1TBJ A;  4Q3T A;  4Q41 A;  1ZPG A;  1T4T A;  4RLA A;  4Q3R C;  3LP7 A;  2CEV A;  2PHO A;  2RLA A;  4Q42 A;  3MFV A;  4MYK A;  1WVA A;  4I06 A;  3E6K A;  4ITY A;  4GSZ A;  2ZAV A;  3LP4 A;  4RHM A;  5HJA A;  1P8S A;  3SJT A;  3NIO A;  4MYN A;  5RLA A;  1T4R A;  4Q3S A;  3NIP A;  1T4S A;  4IU5 A;  3CEV A;  1D3V A;  4Q3Q A;  3E8Q A;  1P8N A;  4IU1 A;  4IE3 A;  4GSM A;  3M1R A;  1WOI A;  3SL0 A;  3TF3 A;  2PLL A;  4HWW A;  3RLA A;  1TBL A;  5CEV A;  3GMZ A;  1T4P A;  4Q3V A;  3SL1 A;  3MJL A;  3KV2 A;  4IE2 A;  1WOG A;  3MMR A;  3NIQ A;  3MFW A;  1P8O A;  4FCI A;  3DJ8 A;  4RHI A;  3THH A;  1ZPE A;  3F80 A;  4MYL A;  4IU4 A;  4G3H A;  3GN0 A;  4HXQ A;  4IE1 A;  4Q3P A;  4IXU A;  4Q40 A;  1XFK A;  4Q3R A;  4GSV A;  3E9B A;  3TH7 A;  1HQF A;  3E8Z A;  4Q3U A;  4MYF A;  1P8M A;  4GWC A;  4RHK A;  1TBH A;  1GQ7 A;  1HQ5 A;  1T5F A;  4RHL A;  3THJ A;  1WVB A;  1PQ3 A;  1WOH A; 
#chains in the Genus database with same CATH topology
 3C0Y A;  4QA5 A;  2EF4 A;  4RHQ A;  4HZE A;  2A0M A;  4MXR A;  5G1A A;  5G0I A;  3THE A;  3E6V A;  4FCK A;  1CEV A;  1T5G A;  4QA1 A;  5HJ9 A;  5G1B A;  4CBY A;  3F0R A;  1GQ6 A;  2EIV A;  5D1B A;  5D1C A;  4BKX B;  1P8R A;  1P8Q A;  4BZ8 A;  1ZZ0 A;  3SKK A;  1P8P A;  4IU0 A;  3PZL A;  4LY1 A;  2VQW G;  5G0H A;  4ZUN A;  1HQX A;  1HQG A;  4RN1 A;  2EF5 A;  5G10 A;  3EWF A;  4BZ6 A;  1RLA A;  2PHA A;  5G0G A;  3MAX A;  4RHJ A;  3SFH A;  5EEN A;  1TA1 A;  5EFH A;  2AEB A;  4GWD A;  1HQH A;  4DZ4 A;  1R1O A;  1T64 A;  5EEM A;  2VQJ A;  3LHL A;  2GH6 A;  3Q9B A;  4IXV A;  1TBJ A;  5FUE A;  5LI3 A;  5IWG A;  5THV A;  4Q3T A;  4Q41 A;  5G0Y A;  5EEF A;  1ZPG A;  1T4T A;  4RLA A;  4Q3R C;  3LP7 A;  5DC5 A;  5EFG A;  4CEV A;  4BZ9 A;  3ZNR A;  2CEV A;  2PHO A;  2RLA A;  5DC6 A;  5IX0 A;  4Q42 A;  5THU A;  3MFV A;  3MZ7 A;  4QA3 A;  5DC7 A;  4MYK A;  4BZ5 A;  1WVA A;  4I06 A;  3E6K A;  3EZT A;  4ITY A;  5EFN A;  3Q9E A;  2VQM A;  4GSZ A;  2ZAV A;  4A69 A;  4CBT A;  3LP4 A;  4RHM A;  3C0Z A;  5HJA A;  1P8S A;  3MZ6 A;  1T67 A;  1VKG A;  3SJT A;  3NIO A;  3F06 A;  4MYN A;  5RLA A;  1T4R A;  5THT A;  4Q3S A;  3NIP A;  1T4S A;  2V5W A;  4IU5 A;  3CEV A;  5THS A;  1D3V A;  4Q3Q A;  5G3W A;  4CQF A;  4ZUQ A;  2VCG A;  4QA0 A;  3E8Q A;  1P8N A;  5G1C A;  4IU1 A;  4ZUM A;  3ZNS A;  5EFB D;  2VQV A;  4IE3 A;  1C3S A;  4GSM A;  5FCW A;  5EFK B;  3M1R A;  1WOI A;  3SL0 A;  4BZ7 A;  3TF3 A;  2PLL A;  4HWW A;  3RLA A;  4ZUP A;  1C3P A;  1ZZ1 A;  4QA6 A;  1TBL A;  5G0J A;  2V5X A;  3GMZ A;  5CEV A;  1T4P A;  4Q3V A;  5EF8 A;  3SL1 A;  3MJL A;  5A2S A;  3KV2 A;  4IE2 A;  1WOG A;  3MMR A;  3NIQ A;  1P8O A;  3MFW A;  3DJ8 A;  4FCI A;  4RHI A;  5DC8 A;  3THH A;  1ZPE A;  3F80 A;  3EZP A;  4MYL A;  4IU4 A;  5D1D A;  3Q9C A;  4G3H A;  3SFF A;  3GN0 A;  3RQD A;  3MEN A;  4HXQ A;  4RN0 A;  4IE1 A;  4Q3P A;  4IXU A;  5EF7 A;  5EEK A;  5G12 A;  5BWZ A;  4Q40 A;  1XFK A;  4Q3R A;  4GSV A;  3Q9F A;  3F07 A;  4LXZ A;  1T69 A;  3E9B A;  4QA2 A;  5G13 A;  3TH7 A;  4ZUR A;  1HQF A;  4RN2 A;  2VQO A;  3E8Z A;  5EEI A;  4Q3U A;  3MZ4 A;  1P8M A;  4MYF A;  4GWC A;  4RHK A;  4ZUO A;  3C10 A;  2VQQ A;  1TBH A;  1GQ7 A;  5JI5 A;  3MZ3 A;  5EFJ D;  1HQ5 A;  5G0X A;  1T5F A;  4RHL A;  3THJ A;  1WVB A;  1W22 A;  1PQ3 A;  4QA7 A;  1C3R A;  5G11 A;  5ICN B;  1ZZ3 A;  4QA4 A;  1WOH A;  3EW8 A;  5G17 A; 
#chains in the Genus database with same CATH homology
 4RHQ A;  2EF4 A;  4HZE A;  2A0M A;  4MXR A;  3THE A;  3E6V A;  4FCK A;  1CEV A;  1T5G A;  5HJ9 A;  4CEV A;  1GQ6 A;  2EIV A;  1P8R A;  1P8Q A;  3SKK A;  1P8P A;  4IU0 A;  3PZL A;  1HQX A;  1HQG A;  2EF5 A;  1RLA A;  2PHA A;  4RHJ A;  1TA1 A;  2AEB A;  4GWD A;  1HQH A;  4DZ4 A;  1R1O A;  3LHL A;  4IXV A;  1TBJ A;  4Q3T A;  4Q41 A;  1ZPG A;  1T4T A;  4RLA A;  4Q3R C;  3LP7 A;  2CEV A;  2PHO A;  2RLA A;  4Q42 A;  3MFV A;  4MYK A;  1WVA A;  4I06 A;  3E6K A;  4ITY A;  4GSZ A;  2ZAV A;  3LP4 A;  4RHM A;  5HJA A;  1P8S A;  3SJT A;  3NIO A;  4MYN A;  5RLA A;  1T4R A;  4Q3S A;  3NIP A;  1T4S A;  4IU5 A;  3CEV A;  1D3V A;  4Q3Q A;  3E8Q A;  1P8N A;  4IU1 A;  4IE3 A;  4GSM A;  3M1R A;  1WOI A;  3SL0 A;  3TF3 A;  2PLL A;  4HWW A;  3RLA A;  1TBL A;  5CEV A;  3GMZ A;  1T4P A;  4Q3V A;  3SL1 A;  3MJL A;  3KV2 A;  4IE2 A;  1WOG A;  3MMR A;  3NIQ A;  3MFW A;  1P8O A;  4FCI A;  3DJ8 A;  4RHI A;  3THH A;  1ZPE A;  3F80 A;  4MYL A;  4IU4 A;  4G3H A;  3GN0 A;  4HXQ A;  4IE1 A;  4Q3P A;  4IXU A;  4Q40 A;  1XFK A;  4Q3R A;  4GSV A;  3E9B A;  3TH7 A;  1HQF A;  3E8Z A;  4Q3U A;  4MYF A;  1P8M A;  4GWC A;  4RHK A;  1TBH A;  1GQ7 A;  1HQ5 A;  1T5F A;  4RHL A;  3THJ A;  1WVB A;  1PQ3 A;  1WOH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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