1P8RA

Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase i.
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
308
structure length
308
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDESMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase 1
total genus 105
structure length 308
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2003-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1p8rA00
4DZ4A 1WOHA 3SKKA 1TBLA 4Q40A 1ZPEA 3E6VA 2EIVA 3E6KA 1GQ6A 3GN0A 3SJTA 4Q3RC 1T5GA 4Q42A 4RLAA 4GWCA 4HXQA 3MFWA 1T5FA 1T4SA 2ZAVA 4Q3VA 3E9BA 3NIQA 1R1OA 4ITYA 4IE1A 1HQ5A 2PHOA 3NIOA 5CEVA 2EF4A 1TA1A 4Q3UA 1XFKA 1RLAA 4Q3TA 1WOGA 3GMZA 4Q41A 1WVAA 4FCIA 1T4PA 4Q3PA 1CEVA 2EF5A 4RHMA 3M1RA 1TBJA 4MXRA 3PZLA 5HJAA 4GSVA 4IE2A 4IU5A 4GSMA 3F80A 3THHA 4Q3SA 2CEVA 3LP4A 4HWWA 4RHIA 4CEVA 3RLAA 4RHKA 4IU1A 3LHLA 3LP7A 4IE3A 1P8OA 2RLAA 1P8PA 4IU4A 3DJ8A 3E8QA 4G3HA 4IXVA 4I06A 3E8ZA 3THEA 4MYLA 1WVBA 1HQXA 4Q3QA 4GSZA 1P8RA 4IU0A 4MYNA 3THJA 2A0MA 1P8SA 1HQGA 4IXUA 5HJ9A 3TH7A 1TBHA 2PLLA 3SL0A 3CEVA 1HQHA 4HZEA 3TF3A 1P8QA 3KV2A 4RHQA 1PQ3A 3MMRA 4GWDA 4FCKA 1D3VA 1T4RA 4RHJA 2AEBA 1P8NA 3SL1A 1T4TA 4RHLA 4Q3RA 3NIPA 1ZPGA 1HQFA 1P8MA 3MJLA 1GQ7A 1WOIA 2PHAA 3MFVA 5RLAA 4MYFA 4MYKA
chains in the Genus database with same CATH superfamily
5THSA 4DZ4A 4ZUOA 3EZPA 3MZ3A 2VQJA 1WOHA 5EEFA 1TBLA 4QA7A 3SKKA 4Q40A 1ZPEA 3F06A 5ICNB 1C3RA 3E6VA 2EIVA 3MAXA 3E6KA 5G0GA 3ZNSA 1GQ6A 3SFHA 3GN0A 3SJTA 4QA6A 3Q9BA 4Q3RC 5G0JA 1T5GA 4Q42A 4RLAA 4GWCA 2VQQA 3MZ4A 4HXQA 5G0IA 3MFWA 1T5FA 1C3SA 1T4SA 3F0RA 2VQVA 4RN1A 2ZAVA 3Q9EA 4Q3VA 3MZ7A 1T69A 3E9BA 3NIQA 1R1OA 5EFKB 4ITYA 4IE1A 1HQ5A 5FCWA 5BWZA 2PHOA 3NIOA 5CEVA 2EF4A 1TA1A 5LI3A 5G3WA 4LXZA 4Q3UA 1XFKA 1RLAA 2VQOA 4Q3TA 1ZZ1A 5EEMA 1WOGA 3C10A 5EFJD 5G13A 3GMZA 3MENA 4Q41A 1WVAA 4FCIA 1T4PA 4Q3PA 1CEVA 2VQWG 2EF5A 4BZ6A 4RHMA 3M1RA 4BZ7A 1TBJA 4MXRA 4BZ9A 3PZLA 5HJAA 5G12A 3EW8A 4GSVA 5IWGA 4IE2A 4CBTA 4IU5A 4ZUPA 5DC6A 4GSMA 3F80A 3THHA 1T67A 4Q3SA 2CEVA 3LP4A 4HWWA 4RHIA 4CEVA 3RLAA 5G17A 4RHKA 5EFHA 5G1BA 4A69A 4BZ8A 4IU1A 3LHLA 5DC8A 3LP7A 4IE3A 1P8OA 2RLAA 5G1CA 4QA5A 5EF7A 1P8PA 4QA1A 2VQMA 4IU4A 5G0XA 5G1AA 4CQFA 2V5XA 3C0ZA 3DJ8A 2V5WA 3E8QA 5IX0A 4G3HA 4IXVA 4I06A 3E8ZA 5THTA 4MYLA 3C0YA 5G0HA 4LY1A 5G0YA 3THEA 5D1DA 4ZUQA 3RQDA 1WVBA 3EZTA 5JI5A 1HQXA 4Q3QA 4QA3A 4GSZA 1P8RA 1ZZ3A 4IU0A 4CBYA 5DC5A 5D1CA 4BZ5A 3F07A 4MYNA 3THJA 5EFBD 3MZ6A 2A0MA 1P8SA 1W22A 5EEKA 1HQGA 1T64A 4IXUA 1ZZ0A 5HJ9A 5THVA 4QA4A 3TH7A 1TBHA 2PLLA 3SL0A 3CEVA 4QA2A 5EFNA 4RN0A 1HQHA 1C3PA 4HZEA 5EFGA 3TF3A 4ZUMA 1P8QA 3KV2A 4RHQA 1PQ3A 3MMRA 5THUA 4RN2A 5A2SA 3Q9FA 4GWDA 4QA0A 3EWFA 4FCKA 1D3VA 1T4RA 4RHJA 2AEBA 5EENA 5D1BA 1P8NA 1VKGA 3Q9CA 4ZUNA 4ZURA 5FUEA 3SL1A 3ZNRA 5EF8A 1T4TA 4BKXB 4RHLA 5EEIA 5G11A 5G10A 4Q3RA 3SFFA 3NIPA 1ZPGA 1HQFA 1P8MA 3MJLA 1GQ7A 1WOIA 2PHAA 5DC7A 3MFVA 2GH6A 4MYKA 5RLAA 4MYFA 2VCGA
chains in the Genus database with same CATH topology
4DZ4A 1WOHA 3SKKA 1TBLA 4Q40A 1ZPEA 3E6VA 2EIVA 3E6KA 1GQ6A 3GN0A 3SJTA 4Q3RC 1T5GA 4Q42A 4RLAA 4GWCA 4HXQA 3MFWA 1T5FA 1T4SA 2ZAVA 4Q3VA 3E9BA 3NIQA 1R1OA 4ITYA 4IE1A 1HQ5A 2PHOA 3NIOA 5CEVA 2EF4A 1TA1A 4Q3UA 1XFKA 1RLAA 4Q3TA 1WOGA 3GMZA 4Q41A 1WVAA 4FCIA 1T4PA 4Q3PA 1CEVA 2EF5A 4RHMA 3M1RA 1TBJA 4MXRA 3PZLA 5HJAA 4GSVA 4IE2A 4IU5A 4GSMA 3F80A 3THHA 4Q3SA 2CEVA 3LP4A 4HWWA 4RHIA 4CEVA 3RLAA 4RHKA 4IU1A 3LHLA 3LP7A 4IE3A 1P8OA 2RLAA 1P8PA 4IU4A 3DJ8A 3E8QA 4G3HA 4IXVA 4I06A 3E8ZA 3THEA 4MYLA 1WVBA 1HQXA 4Q3QA 4GSZA 1P8RA 4IU0A 4MYNA 3THJA 2A0MA 1P8SA 1HQGA 4IXUA 5HJ9A 3TH7A 1TBHA 2PLLA 3SL0A 3CEVA 1HQHA 4HZEA 3TF3A 1P8QA 3KV2A 4RHQA 1PQ3A 3MMRA 4GWDA 4FCKA 1D3VA 1T4RA 4RHJA 2AEBA 1P8NA 3SL1A 1T4TA 4RHLA 4Q3RA 3NIPA 1ZPGA 1HQFA 1P8MA 3MJLA 1GQ7A 1WOIA 2PHAA 3MFVA 5RLAA 4MYFA 4MYKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DZ4 A;  1WOH A;  3SKK A;  1TBL A;  4Q40 A;  1ZPE A;  3E6V A;  2EIV A;  3E6K A;  1GQ6 A;  3GN0 A;  3SJT A;  4Q3R C;  1T5G A;  4Q42 A;  4RLA A;  4GWC A;  4HXQ A;  3MFW A;  1T5F A;  1T4S A;  2ZAV A;  4Q3V A;  3E9B A;  3NIQ A;  1R1O A;  4ITY A;  4IE1 A;  1HQ5 A;  2PHO A;  3NIO A;  5CEV A;  2EF4 A;  1TA1 A;  4Q3U A;  1XFK A;  1RLA A;  4Q3T A;  1WOG A;  3GMZ A;  4Q41 A;  1WVA A;  4FCI A;  1T4P A;  4Q3P A;  1CEV A;  2EF5 A;  4RHM A;  3M1R A;  1TBJ A;  4MXR A;  3PZL A;  5HJA A;  4GSV A;  4IE2 A;  4IU5 A;  4GSM A;  3F80 A;  3THH A;  4Q3S A;  2CEV A;  3LP4 A;  4HWW A;  4RHI A;  4CEV A;  3RLA A;  4RHK A;  4IU1 A;  3LHL A;  3LP7 A;  4IE3 A;  1P8O A;  2RLA A;  1P8P A;  4IU4 A;  3DJ8 A;  3E8Q A;  4G3H A;  4IXV A;  4I06 A;  3E8Z A;  3THE A;  4MYL A;  1WVB A;  1HQX A;  4Q3Q A;  4GSZ A;  1P8R A;  4IU0 A;  4MYN A;  3THJ A;  2A0M A;  1P8S A;  1HQG A;  4IXU A;  5HJ9 A;  3TH7 A;  1TBH A;  2PLL A;  3SL0 A;  3CEV A;  1HQH A;  4HZE A;  3TF3 A;  1P8Q A;  3KV2 A;  4RHQ A;  1PQ3 A;  3MMR A;  4GWD A;  4FCK A;  1D3V A;  1T4R A;  4RHJ A;  2AEB A;  1P8N A;  3SL1 A;  1T4T A;  4RHL A;  4Q3R A;  3NIP A;  1ZPG A;  1HQF A;  1P8M A;  3MJL A;  1GQ7 A;  1WOI A;  2PHA A;  3MFV A;  5RLA A;  4MYF A;  4MYK A; 
#chains in the Genus database with same CATH topology
 5THS A;  4DZ4 A;  4ZUO A;  3EZP A;  3MZ3 A;  2VQJ A;  1WOH A;  5EEF A;  1TBL A;  4QA7 A;  3SKK A;  4Q40 A;  1ZPE A;  3F06 A;  5ICN B;  1C3R A;  3E6V A;  2EIV A;  3MAX A;  3E6K A;  5G0G A;  3ZNS A;  1GQ6 A;  3SFH A;  3GN0 A;  3SJT A;  4QA6 A;  3Q9B A;  4Q3R C;  5G0J A;  1T5G A;  4Q42 A;  4RLA A;  4GWC A;  2VQQ A;  3MZ4 A;  4HXQ A;  5G0I A;  3MFW A;  1T5F A;  1C3S A;  1T4S A;  3F0R A;  2VQV A;  4RN1 A;  2ZAV A;  3Q9E A;  4Q3V A;  3MZ7 A;  1T69 A;  3E9B A;  3NIQ A;  1R1O A;  5EFK B;  4ITY A;  4IE1 A;  1HQ5 A;  5FCW A;  5BWZ A;  2PHO A;  3NIO A;  5CEV A;  2EF4 A;  1TA1 A;  5LI3 A;  5G3W A;  4LXZ A;  4Q3U A;  1XFK A;  1RLA A;  2VQO A;  4Q3T A;  1ZZ1 A;  5EEM A;  1WOG A;  3C10 A;  5EFJ D;  5G13 A;  3GMZ A;  3MEN A;  4Q41 A;  1WVA A;  4FCI A;  1T4P A;  4Q3P A;  1CEV A;  2VQW G;  2EF5 A;  4BZ6 A;  4RHM A;  3M1R A;  4BZ7 A;  1TBJ A;  4MXR A;  4BZ9 A;  3PZL A;  5HJA A;  5G12 A;  3EW8 A;  4GSV A;  5IWG A;  4IE2 A;  4CBT A;  4IU5 A;  4ZUP A;  5DC6 A;  4GSM A;  3F80 A;  3THH A;  1T67 A;  4Q3S A;  2CEV A;  3LP4 A;  4HWW A;  4RHI A;  4CEV A;  3RLA A;  5G17 A;  4RHK A;  5EFH A;  5G1B A;  4A69 A;  4BZ8 A;  4IU1 A;  3LHL A;  5DC8 A;  3LP7 A;  4IE3 A;  1P8O A;  2RLA A;  5G1C A;  4QA5 A;  5EF7 A;  1P8P A;  4QA1 A;  2VQM A;  4IU4 A;  5G0X A;  5G1A A;  4CQF A;  2V5X A;  3C0Z A;  3DJ8 A;  2V5W A;  3E8Q A;  5IX0 A;  4G3H A;  4IXV A;  4I06 A;  3E8Z A;  5THT A;  4MYL A;  3C0Y A;  5G0H A;  4LY1 A;  5G0Y A;  3THE A;  5D1D A;  4ZUQ A;  3RQD A;  1WVB A;  3EZT A;  5JI5 A;  1HQX A;  4Q3Q A;  4QA3 A;  4GSZ A;  1P8R A;  1ZZ3 A;  4IU0 A;  4CBY A;  5DC5 A;  5D1C A;  4BZ5 A;  3F07 A;  4MYN A;  3THJ A;  5EFB D;  3MZ6 A;  2A0M A;  1P8S A;  1W22 A;  5EEK A;  1HQG A;  1T64 A;  4IXU A;  1ZZ0 A;  5HJ9 A;  5THV A;  4QA4 A;  3TH7 A;  1TBH A;  2PLL A;  3SL0 A;  3CEV A;  4QA2 A;  5EFN A;  4RN0 A;  1HQH A;  1C3P A;  4HZE A;  5EFG A;  3TF3 A;  4ZUM A;  1P8Q A;  3KV2 A;  4RHQ A;  1PQ3 A;  3MMR A;  5THU A;  4RN2 A;  5A2S A;  3Q9F A;  4GWD A;  4QA0 A;  3EWF A;  4FCK A;  1D3V A;  1T4R A;  4RHJ A;  2AEB A;  5EEN A;  5D1B A;  1P8N A;  1VKG A;  3Q9C A;  4ZUN A;  4ZUR A;  5FUE A;  3SL1 A;  3ZNR A;  5EF8 A;  1T4T A;  4BKX B;  4RHL A;  5EEI A;  5G11 A;  5G10 A;  4Q3R A;  3SFF A;  3NIP A;  1ZPG A;  1HQF A;  1P8M A;  3MJL A;  1GQ7 A;  1WOI A;  2PHA A;  5DC7 A;  3MFV A;  2GH6 A;  4MYK A;  5RLA A;  4MYF A;  2VCG A; 
#chains in the Genus database with same CATH homology
 4DZ4 A;  1WOH A;  3SKK A;  1TBL A;  4Q40 A;  1ZPE A;  3E6V A;  2EIV A;  3E6K A;  1GQ6 A;  3GN0 A;  3SJT A;  4Q3R C;  1T5G A;  4Q42 A;  4RLA A;  4GWC A;  4HXQ A;  3MFW A;  1T5F A;  1T4S A;  2ZAV A;  4Q3V A;  3E9B A;  3NIQ A;  1R1O A;  4ITY A;  4IE1 A;  1HQ5 A;  2PHO A;  3NIO A;  5CEV A;  2EF4 A;  1TA1 A;  4Q3U A;  1XFK A;  1RLA A;  4Q3T A;  1WOG A;  3GMZ A;  4Q41 A;  1WVA A;  4FCI A;  1T4P A;  4Q3P A;  1CEV A;  2EF5 A;  4RHM A;  3M1R A;  1TBJ A;  4MXR A;  3PZL A;  5HJA A;  4GSV A;  4IE2 A;  4IU5 A;  4GSM A;  3F80 A;  3THH A;  4Q3S A;  2CEV A;  3LP4 A;  4HWW A;  4RHI A;  4CEV A;  3RLA A;  4RHK A;  4IU1 A;  3LHL A;  3LP7 A;  4IE3 A;  1P8O A;  2RLA A;  1P8P A;  4IU4 A;  3DJ8 A;  3E8Q A;  4G3H A;  4IXV A;  4I06 A;  3E8Z A;  3THE A;  4MYL A;  1WVB A;  1HQX A;  4Q3Q A;  4GSZ A;  1P8R A;  4IU0 A;  4MYN A;  3THJ A;  2A0M A;  1P8S A;  1HQG A;  4IXU A;  5HJ9 A;  3TH7 A;  1TBH A;  2PLL A;  3SL0 A;  3CEV A;  1HQH A;  4HZE A;  3TF3 A;  1P8Q A;  3KV2 A;  4RHQ A;  1PQ3 A;  3MMR A;  4GWD A;  4FCK A;  1D3V A;  1T4R A;  4RHJ A;  2AEB A;  1P8N A;  3SL1 A;  1T4T A;  4RHL A;  4Q3R A;  3NIP A;  1ZPG A;  1HQF A;  1P8M A;  3MJL A;  1GQ7 A;  1WOI A;  2PHA A;  3MFV A;  5RLA A;  4MYF A;  4MYK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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