1PQ3A

Human arginase ii: crystal structure and physiological role in male and female sexual arousal
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
306
structure length
306
Chain Sequence
HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase II, mitochondrial precursor
total genus 108
structure length 306
sequence length 306
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2003-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1pq3A00
4Q3RC 1T5GA 2PHOA 5HJAA 3F80A 4DZ4A 1HQXA 4I06A 3M1RA 3MFVA 3NIOA 2A0MA 3KV2A 1T5FA 4Q41A 3SL1A 3E8QA 1CEVA 4Q3VA 4HZEA 4RHMA 4Q40A 4MYFA 1T4RA 4HXQA 3NIQA 4RHLA 1WVBA 4RHJA 3TH7A 4IE1A 4GSZA 1TBLA 1RLAA 2EF4A 2EIVA 3TF3A 5HJ9A 4Q3QA 1WOHA 4RHIA 4RHKA 3RLAA 1ZPGA 4IU5A 4MYKA 4Q3UA 3GN0A 4RLAA 4MXRA 1P8OA 3MJLA 4FCIA 3LHLA 1GQ7A 1P8MA 1T4TA 1WOIA 4Q3TA 3LP7A 3CEVA 4GWCA 3DJ8A 4GWDA 1P8SA 4IU1A 1GQ6A 4Q3PA 3E6KA 4ITYA 4CEVA 3GMZA 4Q3RA 2RLAA 5RLAA 4IXVA 3SKKA 1D3VA 3SJTA 5CEVA 2AEBA 3NIPA 4FCKA 3E9BA 2PLLA 4IXUA 4RHQA 4IU0A 1TBJA 1HQFA 1HQ5A 1R1OA 3E8ZA 1TA1A 1P8PA 4G3HA 3THHA 2PHAA 2ZAVA 1P8RA 1WVAA 4MYLA 1TBHA 1P8NA 1PQ3A 4GSVA 4Q42A 4GSMA 3E6VA 3SL0A 4Q3SA 1ZPEA 3MMRA 3MFWA 4IE3A 3PZLA 1HQHA 1T4SA 4IU4A 3THJA 4IE2A 4MYNA 1XFKA 1WOGA 2CEVA 3THEA 3LP4A 1T4PA 1P8QA 4HWWA 2EF5A 1HQGA
chains in the Genus database with same CATH superfamily
4Q3RC 3C0ZA 3MZ6A 1T5GA 2PHOA 5FCWA 5HJAA 3F80A 5G12A 1HQXA 4DZ4A 4I06A 3F07A 3M1RA 3MFVA 5EEKA 3NIOA 3EWFA 2A0MA 3KV2A 1T5FA 4QA5A 5EF7A 4Q41A 3SL1A 5EEIA 5EFNA 2VQVA 5G0HA 3SFHA 4BKXB 3E8QA 5G1BA 1CEVA 4Q3VA 4HZEA 4RHMA 4Q40A 5DC7A 3SFFA 4ZUQA 4QA2A 4RN2A 4MYFA 5EEFA 1ZZ0A 5A2SA 1T4RA 2V5WA 4HXQA 3NIQA 3F0RA 4RHLA 5D1BA 1WVBA 5D1DA 5THVA 4RHJA 3TH7A 4IE1A 5EFKB 4LY1A 4GSZA 1ZZ1A 4QA7A 1TBLA 1RLAA 3C0YA 3MAXA 4ZUNA 4QA1A 2EF4A 5IWGA 4QA4A 5G17A 4BZ9A 2EIVA 3TF3A 5HJ9A 4Q3QA 2GH6A 1WOHA 5EFBD 4RHIA 4RHKA 5EFJD 5ICNB 3RLAA 5FUEA 5G0XA 4ZUOA 1ZPGA 4IU5A 4MYKA 4Q3UA 4QA0A 3EZTA 3GN0A 4RN1A 3Q9CA 4RLAA 4ZUPA 4MXRA 5LI3A 1P8OA 3MJLA 4FCIA 3LHLA 1GQ7A 1P8MA 3MZ7A 3F06A 5EEMA 4RN0A 5D1CA 3RQDA 2VQQA 2VQJA 1T4TA 1W22A 2VQMA 3MZ4A 1WOIA 4Q3TA 3LP7A 3CEVA 5G13A 4GWCA 4CBYA 3DJ8A 4GWDA 1P8SA 1T64A 1GQ6A 4IU1A 3E6KA 4Q3PA 5THUA 5THTA 4ITYA 5DC5A 4QA6A 4CQFA 5DC6A 4A69A 3GMZA 3ZNRA 4BZ8A 4CEVA 4Q3RA 2RLAA 5G0JA 4IXVA 4ZUMA 1D3VA 2V5XA 5G0IA 5RLAA 3SKKA 3SJTA 5G3WA 5CEVA 5IX0A 2AEBA 3NIPA 4FCKA 3E9BA 2PLLA 4IXUA 3C10A 4RHQA 5G11A 4IU0A 1TBJA 1HQFA 3MENA 1HQ5A 3MZ3A 3ZNSA 1ZZ3A 5G1CA 1R1OA 1C3SA 3E8ZA 2VQOA 1TA1A 1P8PA 4G3HA 3THHA 3EW8A 3Q9EA 4ZURA 2PHAA 2ZAVA 5G0YA 1P8RA 1WVAA 5EF8A 4MYLA 1TBHA 1P8NA 5EFHA 1PQ3A 1T69A 3EZPA 5EENA 4GSVA 5BWZA 4Q42A 4GSMA 4QA3A 3E6VA 3SL0A 5G0GA 4Q3SA 2VQWG 1T67A 4BZ6A 1ZPEA 4LXZA 3MMRA 3MFWA 4IE3A 1VKGA 4CBTA 5DC8A 3PZLA 1HQHA 1T4SA 4IU4A 1C3PA 3Q9FA 3THJA 5JI5A 4IE2A 5G10A 4MYNA 1C3RA 1XFKA 2VCGA 1WOGA 5THSA 2CEVA 5G1AA 3THEA 4BZ5A 4BZ7A 3LP4A 1T4PA 3Q9BA 5EFGA 1P8QA 4HWWA 2EF5A 1HQGA
chains in the Genus database with same CATH topology
4Q3RC 1T5GA 2PHOA 5HJAA 3F80A 4DZ4A 1HQXA 4I06A 3M1RA 3MFVA 3NIOA 2A0MA 3KV2A 1T5FA 4Q41A 3SL1A 3E8QA 1CEVA 4Q3VA 4HZEA 4RHMA 4Q40A 4MYFA 1T4RA 4HXQA 3NIQA 4RHLA 1WVBA 4RHJA 3TH7A 4IE1A 4GSZA 1TBLA 1RLAA 2EF4A 2EIVA 3TF3A 5HJ9A 4Q3QA 1WOHA 4RHIA 4RHKA 3RLAA 1ZPGA 4IU5A 4MYKA 4Q3UA 3GN0A 4RLAA 4MXRA 1P8OA 3MJLA 4FCIA 3LHLA 1GQ7A 1P8MA 1T4TA 1WOIA 4Q3TA 3LP7A 3CEVA 4GWCA 3DJ8A 4GWDA 1P8SA 4IU1A 1GQ6A 4Q3PA 3E6KA 4ITYA 4CEVA 3GMZA 4Q3RA 2RLAA 5RLAA 4IXVA 3SKKA 1D3VA 3SJTA 5CEVA 2AEBA 3NIPA 4FCKA 3E9BA 2PLLA 4IXUA 4RHQA 4IU0A 1TBJA 1HQFA 1HQ5A 1R1OA 3E8ZA 1TA1A 1P8PA 4G3HA 3THHA 2PHAA 2ZAVA 1P8RA 1WVAA 4MYLA 1TBHA 1P8NA 1PQ3A 4GSVA 4Q42A 4GSMA 3E6VA 3SL0A 4Q3SA 1ZPEA 3MMRA 3MFWA 4IE3A 3PZLA 1HQHA 1T4SA 4IU4A 3THJA 4IE2A 4MYNA 1XFKA 1WOGA 2CEVA 3THEA 3LP4A 1T4PA 1P8QA 4HWWA 2EF5A 1HQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q3R C;  1T5G A;  2PHO A;  5HJA A;  3F80 A;  4DZ4 A;  1HQX A;  4I06 A;  3M1R A;  3MFV A;  3NIO A;  2A0M A;  3KV2 A;  1T5F A;  4Q41 A;  3SL1 A;  3E8Q A;  1CEV A;  4Q3V A;  4HZE A;  4RHM A;  4Q40 A;  4MYF A;  1T4R A;  4HXQ A;  3NIQ A;  4RHL A;  1WVB A;  4RHJ A;  3TH7 A;  4IE1 A;  4GSZ A;  1TBL A;  1RLA A;  2EF4 A;  2EIV A;  3TF3 A;  5HJ9 A;  4Q3Q A;  1WOH A;  4RHI A;  4RHK A;  3RLA A;  1ZPG A;  4IU5 A;  4MYK A;  4Q3U A;  3GN0 A;  4RLA A;  4MXR A;  1P8O A;  3MJL A;  4FCI A;  3LHL A;  1GQ7 A;  1P8M A;  1T4T A;  1WOI A;  4Q3T A;  3LP7 A;  3CEV A;  4GWC A;  3DJ8 A;  4GWD A;  1P8S A;  4IU1 A;  1GQ6 A;  4Q3P A;  3E6K A;  4ITY A;  4CEV A;  3GMZ A;  4Q3R A;  2RLA A;  5RLA A;  4IXV A;  3SKK A;  1D3V A;  3SJT A;  5CEV A;  2AEB A;  3NIP A;  4FCK A;  3E9B A;  2PLL A;  4IXU A;  4RHQ A;  4IU0 A;  1TBJ A;  1HQF A;  1HQ5 A;  1R1O A;  3E8Z A;  1TA1 A;  1P8P A;  4G3H A;  3THH A;  2PHA A;  2ZAV A;  1P8R A;  1WVA A;  4MYL A;  1TBH A;  1P8N A;  1PQ3 A;  4GSV A;  4Q42 A;  4GSM A;  3E6V A;  3SL0 A;  4Q3S A;  1ZPE A;  3MMR A;  3MFW A;  4IE3 A;  3PZL A;  1HQH A;  1T4S A;  4IU4 A;  3THJ A;  4IE2 A;  4MYN A;  1XFK A;  1WOG A;  2CEV A;  3THE A;  3LP4 A;  1T4P A;  1P8Q A;  4HWW A;  2EF5 A;  1HQG A; 
#chains in the Genus database with same CATH topology
 4Q3R C;  3C0Z A;  3MZ6 A;  1T5G A;  2PHO A;  5FCW A;  5HJA A;  3F80 A;  5G12 A;  1HQX A;  4DZ4 A;  4I06 A;  3F07 A;  3M1R A;  3MFV A;  5EEK A;  3NIO A;  3EWF A;  2A0M A;  3KV2 A;  1T5F A;  4QA5 A;  5EF7 A;  4Q41 A;  3SL1 A;  5EEI A;  5EFN A;  2VQV A;  5G0H A;  3SFH A;  4BKX B;  3E8Q A;  5G1B A;  1CEV A;  4Q3V A;  4HZE A;  4RHM A;  4Q40 A;  5DC7 A;  3SFF A;  4ZUQ A;  4QA2 A;  4RN2 A;  4MYF A;  5EEF A;  1ZZ0 A;  5A2S A;  1T4R A;  2V5W A;  4HXQ A;  3NIQ A;  3F0R A;  4RHL A;  5D1B A;  1WVB A;  5D1D A;  5THV A;  4RHJ A;  3TH7 A;  4IE1 A;  5EFK B;  4LY1 A;  4GSZ A;  1ZZ1 A;  4QA7 A;  1TBL A;  1RLA A;  3C0Y A;  3MAX A;  4ZUN A;  4QA1 A;  2EF4 A;  5IWG A;  4QA4 A;  5G17 A;  4BZ9 A;  2EIV A;  3TF3 A;  5HJ9 A;  4Q3Q A;  2GH6 A;  1WOH A;  5EFB D;  4RHI A;  4RHK A;  5EFJ D;  5ICN B;  3RLA A;  5FUE A;  5G0X A;  4ZUO A;  1ZPG A;  4IU5 A;  4MYK A;  4Q3U A;  4QA0 A;  3EZT A;  3GN0 A;  4RN1 A;  3Q9C A;  4RLA A;  4ZUP A;  4MXR A;  5LI3 A;  1P8O A;  3MJL A;  4FCI A;  3LHL A;  1GQ7 A;  1P8M A;  3MZ7 A;  3F06 A;  5EEM A;  4RN0 A;  5D1C A;  3RQD A;  2VQQ A;  2VQJ A;  1T4T A;  1W22 A;  2VQM A;  3MZ4 A;  1WOI A;  4Q3T A;  3LP7 A;  3CEV A;  5G13 A;  4GWC A;  4CBY A;  3DJ8 A;  4GWD A;  1P8S A;  1T64 A;  1GQ6 A;  4IU1 A;  3E6K A;  4Q3P A;  5THU A;  5THT A;  4ITY A;  5DC5 A;  4QA6 A;  4CQF A;  5DC6 A;  4A69 A;  3GMZ A;  3ZNR A;  4BZ8 A;  4CEV A;  4Q3R A;  2RLA A;  5G0J A;  4IXV A;  4ZUM A;  1D3V A;  2V5X A;  5G0I A;  5RLA A;  3SKK A;  3SJT A;  5G3W A;  5CEV A;  5IX0 A;  2AEB A;  3NIP A;  4FCK A;  3E9B A;  2PLL A;  4IXU A;  3C10 A;  4RHQ A;  5G11 A;  4IU0 A;  1TBJ A;  1HQF A;  3MEN A;  1HQ5 A;  3MZ3 A;  3ZNS A;  1ZZ3 A;  5G1C A;  1R1O A;  1C3S A;  3E8Z A;  2VQO A;  1TA1 A;  1P8P A;  4G3H A;  3THH A;  3EW8 A;  3Q9E A;  4ZUR A;  2PHA A;  2ZAV A;  5G0Y A;  1P8R A;  1WVA A;  5EF8 A;  4MYL A;  1TBH A;  1P8N A;  5EFH A;  1PQ3 A;  1T69 A;  3EZP A;  5EEN A;  4GSV A;  5BWZ A;  4Q42 A;  4GSM A;  4QA3 A;  3E6V A;  3SL0 A;  5G0G A;  4Q3S A;  2VQW G;  1T67 A;  4BZ6 A;  1ZPE A;  4LXZ A;  3MMR A;  3MFW A;  4IE3 A;  1VKG A;  4CBT A;  5DC8 A;  3PZL A;  1HQH A;  1T4S A;  4IU4 A;  1C3P A;  3Q9F A;  3THJ A;  5JI5 A;  4IE2 A;  5G10 A;  4MYN A;  1C3R A;  1XFK A;  2VCG A;  1WOG A;  5THS A;  2CEV A;  5G1A A;  3THE A;  4BZ5 A;  4BZ7 A;  3LP4 A;  1T4P A;  3Q9B A;  5EFG A;  1P8Q A;  4HWW A;  2EF5 A;  1HQG A; 
#chains in the Genus database with same CATH homology
 4Q3R C;  1T5G A;  2PHO A;  5HJA A;  3F80 A;  4DZ4 A;  1HQX A;  4I06 A;  3M1R A;  3MFV A;  3NIO A;  2A0M A;  3KV2 A;  1T5F A;  4Q41 A;  3SL1 A;  3E8Q A;  1CEV A;  4Q3V A;  4HZE A;  4RHM A;  4Q40 A;  4MYF A;  1T4R A;  4HXQ A;  3NIQ A;  4RHL A;  1WVB A;  4RHJ A;  3TH7 A;  4IE1 A;  4GSZ A;  1TBL A;  1RLA A;  2EF4 A;  2EIV A;  3TF3 A;  5HJ9 A;  4Q3Q A;  1WOH A;  4RHI A;  4RHK A;  3RLA A;  1ZPG A;  4IU5 A;  4MYK A;  4Q3U A;  3GN0 A;  4RLA A;  4MXR A;  1P8O A;  3MJL A;  4FCI A;  3LHL A;  1GQ7 A;  1P8M A;  1T4T A;  1WOI A;  4Q3T A;  3LP7 A;  3CEV A;  4GWC A;  3DJ8 A;  4GWD A;  1P8S A;  4IU1 A;  1GQ6 A;  4Q3P A;  3E6K A;  4ITY A;  4CEV A;  3GMZ A;  4Q3R A;  2RLA A;  5RLA A;  4IXV A;  3SKK A;  1D3V A;  3SJT A;  5CEV A;  2AEB A;  3NIP A;  4FCK A;  3E9B A;  2PLL A;  4IXU A;  4RHQ A;  4IU0 A;  1TBJ A;  1HQF A;  1HQ5 A;  1R1O A;  3E8Z A;  1TA1 A;  1P8P A;  4G3H A;  3THH A;  2PHA A;  2ZAV A;  1P8R A;  1WVA A;  4MYL A;  1TBH A;  1P8N A;  1PQ3 A;  4GSV A;  4Q42 A;  4GSM A;  3E6V A;  3SL0 A;  4Q3S A;  1ZPE A;  3MMR A;  3MFW A;  4IE3 A;  3PZL A;  1HQH A;  1T4S A;  4IU4 A;  3THJ A;  4IE2 A;  4MYN A;  1XFK A;  1WOG A;  2CEV A;  3THE A;  3LP4 A;  1T4P A;  1P8Q A;  4HWW A;  2EF5 A;  1HQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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