2A0MA

Arginase superfamily protein from trypanosoma cruzi
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
298
structure length
298
Chain Sequence
TDDPRLLSLFSAQREEDADIVIIGFPYDEGCVRNGGRAGAKKGPAAFRFFLQRLGSVNNLELNVDASHLKLYDAGDITASTLEEAHEKLESKVFTVLARGAFPFVIGGGNDQSAPNGRAMLRAFPGDVGVINVDSHLDVRPPLQDGRVHSGTPFRQLLEESSFSGKRFVEFACQGSQCGALHAQYVRDHQGHLMWLSEVRKKGAVAALEDAFGLTGKNTFFSFDVDSLKSSDMPGVSCPAAVGLSAQEAFDMCFLAGKTPTVMMMDMSELNPLVEEYRSPRVAVYMFYHFVLGFATRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of pathogenic protozoa: an overview.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords ARGINASE SUPERFAMILY PROTEIN
total genus 120
structure length 298
sequence length 298
ec nomenclature ec 3.5.3.8: Formimidoylglutamase.
pdb deposition date 2005-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 2a0mA00
4MYFA 2EF5A 1P8MA 2AEBA 3SL0A 1HQXA 2ZAVA 5RLAA 3TF3A 5HJ9A 3E6KA 1XFKA 4ITYA 1D3VA 4Q3UA 3CEVA 4IU1A 1P8NA 3THEA 1R1OA 4Q3RC 4MYLA 1GQ6A 2CEVA 4Q3VA 4HWWA 4RHKA 1WOGA 3NIQA 4Q3SA 1P8PA 1P8QA 3LP7A 4GSVA 3SKKA 4IU5A 3LP4A 3E8ZA 1HQHA 4Q3QA 3M1RA 3RLAA 3GMZA 4IXUA 4GSZA 1TBJA 3MFVA 1HQ5A 2EIVA 2EF4A 1HQFA 4Q3PA 2A0MA 4G3HA 4IE3A 1CEVA 1P8RA 4RHQA 1ZPGA 1T4SA 1RLAA 3E6VA 2PLLA 1ZPEA 3GN0A 1P8OA 4HXQA 4RHJA 1T4PA 1T5FA 3THHA 4Q41A 1WOIA 3SL1A 4RLAA 3TH7A 3MMRA 4HZEA 3MJLA 1PQ3A 1P8SA 2PHOA 4MYNA 4FCKA 3SJTA 2PHAA 3DJ8A 1GQ7A 4GWDA 4GSMA 1HQGA 4RHIA 3E8QA 1T5GA 4MYKA 4IE2A 4IXVA 1WOHA 4IU0A 5CEVA 4RHMA 1T4TA 3F80A 1T4RA 4CEVA 4IU4A 3NIPA 2RLAA 3NIOA 4FCIA 4Q3RA 1TA1A 4GWCA 4MXRA 4DZ4A 4IE1A 4Q40A 1WVBA 4Q42A 1WVAA 4RHLA 3THJA 3KV2A 4I06A 1TBLA 3MFWA 3PZLA 3E9BA 1TBHA 3LHLA 4Q3TA 5HJAA
chains in the Genus database with same CATH superfamily
1VKGA 4MYFA 4BZ8A 5DC6A 2EF5A 1P8MA 4CBTA 3F0RA 2AEBA 5D1DA 3C10A 5EEFA 3SL0A 1HQXA 2ZAVA 5RLAA 5G1BA 5G12A 3F06A 3TF3A 5HJ9A 3E6KA 5G0GA 3ZNRA 1XFKA 3Q9FA 5IX0A 4ITYA 1D3VA 3EWFA 3MZ3A 4Q3UA 3CEVA 4QA7A 5DC8A 2VQOA 1P8NA 4IU1A 5G1CA 3THEA 5G11A 4BZ5A 1R1OA 3MZ7A 1ZZ0A 4A69A 5EENA 4Q3RC 1W22A 4MYLA 4QA2A 4RN2A 5DC5A 3MAXA 4QA1A 5FCWA 1GQ6A 2VQWG 5G10A 2VQJA 2CEVA 5G0HA 5JI5A 4Q3VA 4HWWA 4RHKA 5D1BA 5IWGA 3Q9BA 1WOGA 3NIQA 4Q3SA 1P8PA 1P8QA 3LP7A 5G3WA 2GH6A 4GSVA 3MENA 4QA0A 3SKKA 5G1AA 4IU5A 3LP4A 1C3SA 1T67A 3E8ZA 5EEIA 4CQFA 2V5XA 1HQHA 4RN0A 4BZ6A 4LXZA 3MZ6A 5D1CA 5EFKB 1T69A 3EZTA 4Q3QA 3M1RA 3RLAA 3GMZA 4IXUA 4GSZA 1TBJA 4QA5A 3MFVA 1HQ5A 2EIVA 5G0IA 3ZNSA 2EF4A 1HQFA 3SFFA 4Q3PA 2VQQA 2A0MA 5G13A 4G3HA 5EFGA 5EFBD 4IE3A 1ZZ1A 1CEVA 1P8RA 5EFHA 4RHQA 1ZPGA 1T4SA 1RLAA 3Q9EA 3SFHA 3E6VA 2PLLA 1ZPEA 3GN0A 1P8OA 3Q9CA 4HXQA 4LY1A 4RHJA 4RN1A 5THTA 5FUEA 1T4PA 1T5FA 3THHA 4Q41A 1WOIA 5THVA 1C3PA 4CBYA 1C3RA 3SL1A 2V5WA 3EZPA 2VQVA 5G17A 4RLAA 3TH7A 3MMRA 5BWZA 5THSA 4HZEA 4ZUMA 3MJLA 1PQ3A 4QA4A 3RQDA 1P8SA 5G0XA 2PHOA 4MYNA 4QA6A 4FCKA 4BKXB 3SJTA 2PHAA 3DJ8A 1GQ7A 4GWDA 4GSMA 1HQGA 2VQMA 4RHIA 3E8QA 1T5GA 5ICNB 4MYKA 4IE2A 4IXVA 4ZUPA 1WOHA 5EEMA 4IU0A 5CEVA 4RHMA 1T4TA 3C0YA 2VCGA 5EFNA 3F80A 1T4RA 4CEVA 4IU4A 4ZUOA 5THUA 5EFJD 3NIPA 1T64A 2RLAA 3NIOA 4ZUNA 4ZUQA 4FCIA 4Q3RA 5DC7A 5A2SA 5EF7A 1TA1A 4GWCA 5G0JA 4MXRA 4BZ9A 4DZ4A 4IE1A 4Q40A 1WVBA 5EEKA 1ZZ3A 4Q42A 1WVAA 4RHLA 4ZURA 3EW8A 3MZ4A 3THJA 3KV2A 4I06A 1TBLA 5LI3A 4BZ7A 3F07A 5G0YA 3MFWA 3PZLA 3E9BA 1TBHA 3C0ZA 3LHLA 5EF8A 4Q3TA 4QA3A 5HJAA
chains in the Genus database with same CATH topology
4MYFA 2EF5A 1P8MA 2AEBA 3SL0A 1HQXA 2ZAVA 5RLAA 3TF3A 5HJ9A 3E6KA 1XFKA 4ITYA 1D3VA 4Q3UA 3CEVA 4IU1A 1P8NA 3THEA 1R1OA 4Q3RC 4MYLA 1GQ6A 2CEVA 4Q3VA 4HWWA 4RHKA 1WOGA 3NIQA 4Q3SA 1P8PA 1P8QA 3LP7A 4GSVA 3SKKA 4IU5A 3LP4A 3E8ZA 1HQHA 4Q3QA 3M1RA 3RLAA 3GMZA 4IXUA 4GSZA 1TBJA 3MFVA 1HQ5A 2EIVA 2EF4A 1HQFA 4Q3PA 2A0MA 4G3HA 4IE3A 1CEVA 1P8RA 4RHQA 1ZPGA 1T4SA 1RLAA 3E6VA 2PLLA 1ZPEA 3GN0A 1P8OA 4HXQA 4RHJA 1T4PA 1T5FA 3THHA 4Q41A 1WOIA 3SL1A 4RLAA 3TH7A 3MMRA 4HZEA 3MJLA 1PQ3A 1P8SA 2PHOA 4MYNA 4FCKA 3SJTA 2PHAA 3DJ8A 1GQ7A 4GWDA 4GSMA 1HQGA 4RHIA 3E8QA 1T5GA 4MYKA 4IE2A 4IXVA 1WOHA 4IU0A 5CEVA 4RHMA 1T4TA 3F80A 1T4RA 4CEVA 4IU4A 3NIPA 2RLAA 3NIOA 4FCIA 4Q3RA 1TA1A 4GWCA 4MXRA 4DZ4A 4IE1A 4Q40A 1WVBA 4Q42A 1WVAA 4RHLA 3THJA 3KV2A 4I06A 1TBLA 3MFWA 3PZLA 3E9BA 1TBHA 3LHLA 4Q3TA 5HJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MYF A;  2EF5 A;  1P8M A;  2AEB A;  3SL0 A;  1HQX A;  2ZAV A;  5RLA A;  3TF3 A;  5HJ9 A;  3E6K A;  1XFK A;  4ITY A;  1D3V A;  4Q3U A;  3CEV A;  4IU1 A;  1P8N A;  3THE A;  1R1O A;  4Q3R C;  4MYL A;  1GQ6 A;  2CEV A;  4Q3V A;  4HWW A;  4RHK A;  1WOG A;  3NIQ A;  4Q3S A;  1P8P A;  1P8Q A;  3LP7 A;  4GSV A;  3SKK A;  4IU5 A;  3LP4 A;  3E8Z A;  1HQH A;  4Q3Q A;  3M1R A;  3RLA A;  3GMZ A;  4IXU A;  4GSZ A;  1TBJ A;  3MFV A;  1HQ5 A;  2EIV A;  2EF4 A;  1HQF A;  4Q3P A;  2A0M A;  4G3H A;  4IE3 A;  1CEV A;  1P8R A;  4RHQ A;  1ZPG A;  1T4S A;  1RLA A;  3E6V A;  2PLL A;  1ZPE A;  3GN0 A;  1P8O A;  4HXQ A;  4RHJ A;  1T4P A;  1T5F A;  3THH A;  4Q41 A;  1WOI A;  3SL1 A;  4RLA A;  3TH7 A;  3MMR A;  4HZE A;  3MJL A;  1PQ3 A;  1P8S A;  2PHO A;  4MYN A;  4FCK A;  3SJT A;  2PHA A;  3DJ8 A;  1GQ7 A;  4GWD A;  4GSM A;  1HQG A;  4RHI A;  3E8Q A;  1T5G A;  4MYK A;  4IE2 A;  4IXV A;  1WOH A;  4IU0 A;  5CEV A;  4RHM A;  1T4T A;  3F80 A;  1T4R A;  4CEV A;  4IU4 A;  3NIP A;  2RLA A;  3NIO A;  4FCI A;  4Q3R A;  1TA1 A;  4GWC A;  4MXR A;  4DZ4 A;  4IE1 A;  4Q40 A;  1WVB A;  4Q42 A;  1WVA A;  4RHL A;  3THJ A;  3KV2 A;  4I06 A;  1TBL A;  3MFW A;  3PZL A;  3E9B A;  1TBH A;  3LHL A;  4Q3T A;  5HJA A; 
#chains in the Genus database with same CATH topology
 1VKG A;  4MYF A;  4BZ8 A;  5DC6 A;  2EF5 A;  1P8M A;  4CBT A;  3F0R A;  2AEB A;  5D1D A;  3C10 A;  5EEF A;  3SL0 A;  1HQX A;  2ZAV A;  5RLA A;  5G1B A;  5G12 A;  3F06 A;  3TF3 A;  5HJ9 A;  3E6K A;  5G0G A;  3ZNR A;  1XFK A;  3Q9F A;  5IX0 A;  4ITY A;  1D3V A;  3EWF A;  3MZ3 A;  4Q3U A;  3CEV A;  4QA7 A;  5DC8 A;  2VQO A;  1P8N A;  4IU1 A;  5G1C A;  3THE A;  5G11 A;  4BZ5 A;  1R1O A;  3MZ7 A;  1ZZ0 A;  4A69 A;  5EEN A;  4Q3R C;  1W22 A;  4MYL A;  4QA2 A;  4RN2 A;  5DC5 A;  3MAX A;  4QA1 A;  5FCW A;  1GQ6 A;  2VQW G;  5G10 A;  2VQJ A;  2CEV A;  5G0H A;  5JI5 A;  4Q3V A;  4HWW A;  4RHK A;  5D1B A;  5IWG A;  3Q9B A;  1WOG A;  3NIQ A;  4Q3S A;  1P8P A;  1P8Q A;  3LP7 A;  5G3W A;  2GH6 A;  4GSV A;  3MEN A;  4QA0 A;  3SKK A;  5G1A A;  4IU5 A;  3LP4 A;  1C3S A;  1T67 A;  3E8Z A;  5EEI A;  4CQF A;  2V5X A;  1HQH A;  4RN0 A;  4BZ6 A;  4LXZ A;  3MZ6 A;  5D1C A;  5EFK B;  1T69 A;  3EZT A;  4Q3Q A;  3M1R A;  3RLA A;  3GMZ A;  4IXU A;  4GSZ A;  1TBJ A;  4QA5 A;  3MFV A;  1HQ5 A;  2EIV A;  5G0I A;  3ZNS A;  2EF4 A;  1HQF A;  3SFF A;  4Q3P A;  2VQQ A;  2A0M A;  5G13 A;  4G3H A;  5EFG A;  5EFB D;  4IE3 A;  1ZZ1 A;  1CEV A;  1P8R A;  5EFH A;  4RHQ A;  1ZPG A;  1T4S A;  1RLA A;  3Q9E A;  3SFH A;  3E6V A;  2PLL A;  1ZPE A;  3GN0 A;  1P8O A;  3Q9C A;  4HXQ A;  4LY1 A;  4RHJ A;  4RN1 A;  5THT A;  5FUE A;  1T4P A;  1T5F A;  3THH A;  4Q41 A;  1WOI A;  5THV A;  1C3P A;  4CBY A;  1C3R A;  3SL1 A;  2V5W A;  3EZP A;  2VQV A;  5G17 A;  4RLA A;  3TH7 A;  3MMR A;  5BWZ A;  5THS A;  4HZE A;  4ZUM A;  3MJL A;  1PQ3 A;  4QA4 A;  3RQD A;  1P8S A;  5G0X A;  2PHO A;  4MYN A;  4QA6 A;  4FCK A;  4BKX B;  3SJT A;  2PHA A;  3DJ8 A;  1GQ7 A;  4GWD A;  4GSM A;  1HQG A;  2VQM A;  4RHI A;  3E8Q A;  1T5G A;  5ICN B;  4MYK A;  4IE2 A;  4IXV A;  4ZUP A;  1WOH A;  5EEM A;  4IU0 A;  5CEV A;  4RHM A;  1T4T A;  3C0Y A;  2VCG A;  5EFN A;  3F80 A;  1T4R A;  4CEV A;  4IU4 A;  4ZUO A;  5THU A;  5EFJ D;  3NIP A;  1T64 A;  2RLA A;  3NIO A;  4ZUN A;  4ZUQ A;  4FCI A;  4Q3R A;  5DC7 A;  5A2S A;  5EF7 A;  1TA1 A;  4GWC A;  5G0J A;  4MXR A;  4BZ9 A;  4DZ4 A;  4IE1 A;  4Q40 A;  1WVB A;  5EEK A;  1ZZ3 A;  4Q42 A;  1WVA A;  4RHL A;  4ZUR A;  3EW8 A;  3MZ4 A;  3THJ A;  3KV2 A;  4I06 A;  1TBL A;  5LI3 A;  4BZ7 A;  3F07 A;  5G0Y A;  3MFW A;  3PZL A;  3E9B A;  1TBH A;  3C0Z A;  3LHL A;  5EF8 A;  4Q3T A;  4QA3 A;  5HJA A; 
#chains in the Genus database with same CATH homology
 4MYF A;  2EF5 A;  1P8M A;  2AEB A;  3SL0 A;  1HQX A;  2ZAV A;  5RLA A;  3TF3 A;  5HJ9 A;  3E6K A;  1XFK A;  4ITY A;  1D3V A;  4Q3U A;  3CEV A;  4IU1 A;  1P8N A;  3THE A;  1R1O A;  4Q3R C;  4MYL A;  1GQ6 A;  2CEV A;  4Q3V A;  4HWW A;  4RHK A;  1WOG A;  3NIQ A;  4Q3S A;  1P8P A;  1P8Q A;  3LP7 A;  4GSV A;  3SKK A;  4IU5 A;  3LP4 A;  3E8Z A;  1HQH A;  4Q3Q A;  3M1R A;  3RLA A;  3GMZ A;  4IXU A;  4GSZ A;  1TBJ A;  3MFV A;  1HQ5 A;  2EIV A;  2EF4 A;  1HQF A;  4Q3P A;  2A0M A;  4G3H A;  4IE3 A;  1CEV A;  1P8R A;  4RHQ A;  1ZPG A;  1T4S A;  1RLA A;  3E6V A;  2PLL A;  1ZPE A;  3GN0 A;  1P8O A;  4HXQ A;  4RHJ A;  1T4P A;  1T5F A;  3THH A;  4Q41 A;  1WOI A;  3SL1 A;  4RLA A;  3TH7 A;  3MMR A;  4HZE A;  3MJL A;  1PQ3 A;  1P8S A;  2PHO A;  4MYN A;  4FCK A;  3SJT A;  2PHA A;  3DJ8 A;  1GQ7 A;  4GWD A;  4GSM A;  1HQG A;  4RHI A;  3E8Q A;  1T5G A;  4MYK A;  4IE2 A;  4IXV A;  1WOH A;  4IU0 A;  5CEV A;  4RHM A;  1T4T A;  3F80 A;  1T4R A;  4CEV A;  4IU4 A;  3NIP A;  2RLA A;  3NIO A;  4FCI A;  4Q3R A;  1TA1 A;  4GWC A;  4MXR A;  4DZ4 A;  4IE1 A;  4Q40 A;  1WVB A;  4Q42 A;  1WVA A;  4RHL A;  3THJ A;  3KV2 A;  4I06 A;  1TBL A;  3MFW A;  3PZL A;  3E9B A;  1TBH A;  3LHL A;  4Q3T A;  5HJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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