2CEVA

Arginase from bacillus caldevelox, native structure at ph 8.5
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
298
structure length
298
Chain Sequence
KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 117
structure length 298
sequence length 298
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 2cevA00
3THEA 1WOGA 1HQXA 3NIPA 3LHLA 4RHQA 1T4SA 1P8MA 4Q42A 1T5FA 4GSVA 3E6VA 3SJTA 4IE1A 4MXRA 3M1RA 4Q40A 4DZ4A 5HJAA 1WVAA 3CEVA 3F80A 1GQ7A 3TH7A 1RLAA 1HQ5A 3GMZA 4IU4A 4RHKA 1HQHA 2PLLA 3MJLA 4MYLA 4RHIA 3MFWA 3THJA 5HJ9A 1T4TA 4RHJA 4GWDA 4MYNA 4HZEA 3KV2A 1TBJA 2PHOA 4Q3RA 4RHLA 1P8NA 4IU1A 2EF4A 1ZPGA 4FCKA 1GQ6A 1WOIA 4HXQA 4MYKA 1WOHA 4Q3VA 1ZPEA 4IE3A 3MFVA 4HWWA 1TBHA 4G3HA 1P8OA 1P8RA 3NIOA 1HQFA 4IXVA 4Q3TA 3E6KA 3LP7A 4IU5A 5CEVA 4IXUA 4Q3UA 1R1OA 4Q41A 1T4PA 1T4RA 4ITYA 1T5GA 2EF5A 4GSZA 3RLAA 4I06A 4Q3PA 2PHAA 1TBLA 3PZLA 4RLAA 4CEVA 3THHA 3SKKA 1XFKA 3E8QA 4RHMA 3SL0A 1D3VA 1P8PA 1P8QA 4IU0A 3E8ZA 2ZAVA 3GN0A 1P8SA 3MMRA 4GWCA 1TA1A 2EIVA 1CEVA 3SL1A 4GSMA 4Q3SA 2CEVA 3DJ8A 3TF3A 1PQ3A 1HQGA 5RLAA 3NIQA 2AEBA 4Q3QA 2A0MA 1WVBA 4MYFA 3LP4A 4IE2A 2RLAA 4Q3RC 3E9BA 4FCIA
chains in the Genus database with same CATH superfamily
4RN1A 3THEA 1WOGA 3MAXA 1HQXA 3NIPA 3LHLA 5EF8A 5EENA 4RHQA 1T4SA 5EFGA 1P8MA 4Q42A 4CQFA 1T5FA 5THVA 5G12A 5DC7A 5BWZA 5FCWA 4GSVA 3E6VA 3SJTA 3EWFA 4IE1A 4MXRA 3M1RA 4Q40A 4DZ4A 3MZ3A 5EFKB 5HJAA 1WVAA 2VQQA 5DC8A 3EZPA 3Q9FA 4BZ5A 3CEVA 3F80A 5EEKA 4ZURA 1GQ7A 3TH7A 1RLAA 3SFHA 1HQ5A 3GMZA 4IU4A 4QA3A 4RHKA 1T64A 4BZ6A 5A2SA 1HQHA 2PLLA 3MJLA 4MYLA 4RHIA 3MFWA 3MZ6A 3THJA 3F06A 3C10A 5HJ9A 1VKGA 1T4TA 4RHJA 2VQMA 4GWDA 2GH6A 4MYNA 2V5WA 4HZEA 5G1AA 5G0YA 2VCGA 3KV2A 5G0XA 1C3SA 1TBJA 2PHOA 4LXZA 4Q3RA 4RHLA 1P8NA 5G1BA 5EEMA 4IU1A 5G0JA 3SFFA 3ZNRA 4BZ7A 2EF4A 1ZPGA 4FCKA 1GQ6A 1WOIA 4HXQA 5G0HA 4QA4A 5EEFA 5G1CA 4MYKA 1WOHA 4Q3VA 1ZPEA 4IE3A 3MFVA 4HWWA 3C0ZA 1TBHA 4G3HA 5EEIA 1P8OA 5G0IA 1P8RA 3NIOA 1HQFA 5JI5A 1ZZ0A 4IXVA 4QA0A 5EFNA 4Q3TA 3E6KA 3LP7A 3Q9EA 3Q9CA 4IU5A 5CEVA 4IXUA 4Q3UA 1R1OA 5G10A 4Q41A 4QA2A 1T4PA 1T4RA 5D1CA 4ZUMA 1ZZ1A 4ITYA 3C0YA 1T5GA 2VQVA 1C3RA 5EF7A 4CBYA 2EF5A 4GSZA 3RLAA 3MZ4A 5G17A 4ZUQA 5EFJD 4I06A 5G3WA 4Q3PA 3F07A 2PHAA 1TBLA 3PZLA 4RLAA 4ZUPA 5THUA 5D1DA 4CEVA 3F0RA 3THHA 3RQDA 3SKKA 1XFKA 3E8QA 5D1BA 5G11A 4RHMA 3MZ7A 5EFHA 5EFBD 4QA7A 1C3PA 3SL0A 5THTA 3ZNSA 1D3VA 1P8PA 4BZ9A 1P8QA 4ZUOA 5FUEA 4CBTA 2VQOA 4IU0A 3E8ZA 2ZAVA 3GN0A 1P8SA 3MMRA 5G0GA 1ZZ3A 1TA1A 2EIVA 4GWCA 4QA6A 4ZUNA 5IX0A 1CEVA 5THSA 5G13A 5DC5A 5IWGA 3SL1A 3EW8A 2VQJA 4GSMA 4Q3SA 2CEVA 4RN2A 3DJ8A 4BKXB 3TF3A 1PQ3A 4LY1A 1HQGA 5RLAA 3NIQA 1T69A 5LI3A 4A69A 5ICNB 2AEBA 1T67A 4Q3QA 5DC6A 2A0MA 3MENA 1WVBA 4MYFA 3LP4A 2V5XA 1W22A 2RLAA 3EZTA 4IE2A 4Q3RC 4QA1A 3E9BA 2VQWG 3Q9BA 4FCIA 4RN0A 4QA5A 4BZ8A
chains in the Genus database with same CATH topology
3THEA 1WOGA 1HQXA 3NIPA 3LHLA 4RHQA 1T4SA 1P8MA 4Q42A 1T5FA 4GSVA 3E6VA 3SJTA 4IE1A 4MXRA 3M1RA 4Q40A 4DZ4A 5HJAA 1WVAA 3CEVA 3F80A 1GQ7A 3TH7A 1RLAA 1HQ5A 3GMZA 4IU4A 4RHKA 1HQHA 2PLLA 3MJLA 4MYLA 4RHIA 3MFWA 3THJA 5HJ9A 1T4TA 4RHJA 4GWDA 4MYNA 4HZEA 3KV2A 1TBJA 2PHOA 4Q3RA 4RHLA 1P8NA 4IU1A 2EF4A 1ZPGA 4FCKA 1GQ6A 1WOIA 4HXQA 4MYKA 1WOHA 4Q3VA 1ZPEA 4IE3A 3MFVA 4HWWA 1TBHA 4G3HA 1P8OA 1P8RA 3NIOA 1HQFA 4IXVA 4Q3TA 3E6KA 3LP7A 4IU5A 5CEVA 4IXUA 4Q3UA 1R1OA 4Q41A 1T4PA 1T4RA 4ITYA 1T5GA 2EF5A 4GSZA 3RLAA 4I06A 4Q3PA 2PHAA 1TBLA 3PZLA 4RLAA 4CEVA 3THHA 3SKKA 1XFKA 3E8QA 4RHMA 3SL0A 1D3VA 1P8PA 1P8QA 4IU0A 3E8ZA 2ZAVA 3GN0A 1P8SA 3MMRA 4GWCA 1TA1A 2EIVA 1CEVA 3SL1A 4GSMA 4Q3SA 2CEVA 3DJ8A 3TF3A 1PQ3A 1HQGA 5RLAA 3NIQA 2AEBA 4Q3QA 2A0MA 1WVBA 4MYFA 3LP4A 4IE2A 2RLAA 4Q3RC 3E9BA 4FCIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3THE A;  1WOG A;  1HQX A;  3NIP A;  3LHL A;  4RHQ A;  1T4S A;  1P8M A;  4Q42 A;  1T5F A;  4GSV A;  3E6V A;  3SJT A;  4IE1 A;  4MXR A;  3M1R A;  4Q40 A;  4DZ4 A;  5HJA A;  1WVA A;  3CEV A;  3F80 A;  1GQ7 A;  3TH7 A;  1RLA A;  1HQ5 A;  3GMZ A;  4IU4 A;  4RHK A;  1HQH A;  2PLL A;  3MJL A;  4MYL A;  4RHI A;  3MFW A;  3THJ A;  5HJ9 A;  1T4T A;  4RHJ A;  4GWD A;  4MYN A;  4HZE A;  3KV2 A;  1TBJ A;  2PHO A;  4Q3R A;  4RHL A;  1P8N A;  4IU1 A;  2EF4 A;  1ZPG A;  4FCK A;  1GQ6 A;  1WOI A;  4HXQ A;  4MYK A;  1WOH A;  4Q3V A;  1ZPE A;  4IE3 A;  3MFV A;  4HWW A;  1TBH A;  4G3H A;  1P8O A;  1P8R A;  3NIO A;  1HQF A;  4IXV A;  4Q3T A;  3E6K A;  3LP7 A;  4IU5 A;  5CEV A;  4IXU A;  4Q3U A;  1R1O A;  4Q41 A;  1T4P A;  1T4R A;  4ITY A;  1T5G A;  2EF5 A;  4GSZ A;  3RLA A;  4I06 A;  4Q3P A;  2PHA A;  1TBL A;  3PZL A;  4RLA A;  4CEV A;  3THH A;  3SKK A;  1XFK A;  3E8Q A;  4RHM A;  3SL0 A;  1D3V A;  1P8P A;  1P8Q A;  4IU0 A;  3E8Z A;  2ZAV A;  3GN0 A;  1P8S A;  3MMR A;  4GWC A;  1TA1 A;  2EIV A;  1CEV A;  3SL1 A;  4GSM A;  4Q3S A;  2CEV A;  3DJ8 A;  3TF3 A;  1PQ3 A;  1HQG A;  5RLA A;  3NIQ A;  2AEB A;  4Q3Q A;  2A0M A;  1WVB A;  4MYF A;  3LP4 A;  4IE2 A;  2RLA A;  4Q3R C;  3E9B A;  4FCI A; 
#chains in the Genus database with same CATH topology
 4RN1 A;  3THE A;  1WOG A;  3MAX A;  1HQX A;  3NIP A;  3LHL A;  5EF8 A;  5EEN A;  4RHQ A;  1T4S A;  5EFG A;  1P8M A;  4Q42 A;  4CQF A;  1T5F A;  5THV A;  5G12 A;  5DC7 A;  5BWZ A;  5FCW A;  4GSV A;  3E6V A;  3SJT A;  3EWF A;  4IE1 A;  4MXR A;  3M1R A;  4Q40 A;  4DZ4 A;  3MZ3 A;  5EFK B;  5HJA A;  1WVA A;  2VQQ A;  5DC8 A;  3EZP A;  3Q9F A;  4BZ5 A;  3CEV A;  3F80 A;  5EEK A;  4ZUR A;  1GQ7 A;  3TH7 A;  1RLA A;  3SFH A;  1HQ5 A;  3GMZ A;  4IU4 A;  4QA3 A;  4RHK A;  1T64 A;  4BZ6 A;  5A2S A;  1HQH A;  2PLL A;  3MJL A;  4MYL A;  4RHI A;  3MFW A;  3MZ6 A;  3THJ A;  3F06 A;  3C10 A;  5HJ9 A;  1VKG A;  1T4T A;  4RHJ A;  2VQM A;  4GWD A;  2GH6 A;  4MYN A;  2V5W A;  4HZE A;  5G1A A;  5G0Y A;  2VCG A;  3KV2 A;  5G0X A;  1C3S A;  1TBJ A;  2PHO A;  4LXZ A;  4Q3R A;  4RHL A;  1P8N A;  5G1B A;  5EEM A;  4IU1 A;  5G0J A;  3SFF A;  3ZNR A;  4BZ7 A;  2EF4 A;  1ZPG A;  4FCK A;  1GQ6 A;  1WOI A;  4HXQ A;  5G0H A;  4QA4 A;  5EEF A;  5G1C A;  4MYK A;  1WOH A;  4Q3V A;  1ZPE A;  4IE3 A;  3MFV A;  4HWW A;  3C0Z A;  1TBH A;  4G3H A;  5EEI A;  1P8O A;  5G0I A;  1P8R A;  3NIO A;  1HQF A;  5JI5 A;  1ZZ0 A;  4IXV A;  4QA0 A;  5EFN A;  4Q3T A;  3E6K A;  3LP7 A;  3Q9E A;  3Q9C A;  4IU5 A;  5CEV A;  4IXU A;  4Q3U A;  1R1O A;  5G10 A;  4Q41 A;  4QA2 A;  1T4P A;  1T4R A;  5D1C A;  4ZUM A;  1ZZ1 A;  4ITY A;  3C0Y A;  1T5G A;  2VQV A;  1C3R A;  5EF7 A;  4CBY A;  2EF5 A;  4GSZ A;  3RLA A;  3MZ4 A;  5G17 A;  4ZUQ A;  5EFJ D;  4I06 A;  5G3W A;  4Q3P A;  3F07 A;  2PHA A;  1TBL A;  3PZL A;  4RLA A;  4ZUP A;  5THU A;  5D1D A;  4CEV A;  3F0R A;  3THH A;  3RQD A;  3SKK A;  1XFK A;  3E8Q A;  5D1B A;  5G11 A;  4RHM A;  3MZ7 A;  5EFH A;  5EFB D;  4QA7 A;  1C3P A;  3SL0 A;  5THT A;  3ZNS A;  1D3V A;  1P8P A;  4BZ9 A;  1P8Q A;  4ZUO A;  5FUE A;  4CBT A;  2VQO A;  4IU0 A;  3E8Z A;  2ZAV A;  3GN0 A;  1P8S A;  3MMR A;  5G0G A;  1ZZ3 A;  1TA1 A;  2EIV A;  4GWC A;  4QA6 A;  4ZUN A;  5IX0 A;  1CEV A;  5THS A;  5G13 A;  5DC5 A;  5IWG A;  3SL1 A;  3EW8 A;  2VQJ A;  4GSM A;  4Q3S A;  2CEV A;  4RN2 A;  3DJ8 A;  4BKX B;  3TF3 A;  1PQ3 A;  4LY1 A;  1HQG A;  5RLA A;  3NIQ A;  1T69 A;  5LI3 A;  4A69 A;  5ICN B;  2AEB A;  1T67 A;  4Q3Q A;  5DC6 A;  2A0M A;  3MEN A;  1WVB A;  4MYF A;  3LP4 A;  2V5X A;  1W22 A;  2RLA A;  3EZT A;  4IE2 A;  4Q3R C;  4QA1 A;  3E9B A;  2VQW G;  3Q9B A;  4FCI A;  4RN0 A;  4QA5 A;  4BZ8 A; 
#chains in the Genus database with same CATH homology
 3THE A;  1WOG A;  1HQX A;  3NIP A;  3LHL A;  4RHQ A;  1T4S A;  1P8M A;  4Q42 A;  1T5F A;  4GSV A;  3E6V A;  3SJT A;  4IE1 A;  4MXR A;  3M1R A;  4Q40 A;  4DZ4 A;  5HJA A;  1WVA A;  3CEV A;  3F80 A;  1GQ7 A;  3TH7 A;  1RLA A;  1HQ5 A;  3GMZ A;  4IU4 A;  4RHK A;  1HQH A;  2PLL A;  3MJL A;  4MYL A;  4RHI A;  3MFW A;  3THJ A;  5HJ9 A;  1T4T A;  4RHJ A;  4GWD A;  4MYN A;  4HZE A;  3KV2 A;  1TBJ A;  2PHO A;  4Q3R A;  4RHL A;  1P8N A;  4IU1 A;  2EF4 A;  1ZPG A;  4FCK A;  1GQ6 A;  1WOI A;  4HXQ A;  4MYK A;  1WOH A;  4Q3V A;  1ZPE A;  4IE3 A;  3MFV A;  4HWW A;  1TBH A;  4G3H A;  1P8O A;  1P8R A;  3NIO A;  1HQF A;  4IXV A;  4Q3T A;  3E6K A;  3LP7 A;  4IU5 A;  5CEV A;  4IXU A;  4Q3U A;  1R1O A;  4Q41 A;  1T4P A;  1T4R A;  4ITY A;  1T5G A;  2EF5 A;  4GSZ A;  3RLA A;  4I06 A;  4Q3P A;  2PHA A;  1TBL A;  3PZL A;  4RLA A;  4CEV A;  3THH A;  3SKK A;  1XFK A;  3E8Q A;  4RHM A;  3SL0 A;  1D3V A;  1P8P A;  1P8Q A;  4IU0 A;  3E8Z A;  2ZAV A;  3GN0 A;  1P8S A;  3MMR A;  4GWC A;  1TA1 A;  2EIV A;  1CEV A;  3SL1 A;  4GSM A;  4Q3S A;  2CEV A;  3DJ8 A;  3TF3 A;  1PQ3 A;  1HQG A;  5RLA A;  3NIQ A;  2AEB A;  4Q3Q A;  2A0M A;  1WVB A;  4MYF A;  3LP4 A;  4IE2 A;  2RLA A;  4Q3R C;  3E9B A;  4FCI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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