2PLLA

Crystal structure of perdeuterated human arginase i
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
314
structure length
314
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Expression, purification, assay, and crystal structure of perdeuterated human arginase I
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords arginase-1
total genus 112
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2007-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 2pllA00
4Q3RC 1R1OA 1T4PA 1T5FA 1HQGA 1CEVA 3M1RA 3LHLA 4HWWA 1RLAA 2EF4A 1HQHA 5RLAA 4RHIA 4RHMA 4Q3TA 3MFWA 5HJAA 1TBLA 3DJ8A 3LP4A 4Q42A 4MYLA 4FCKA 1GQ7A 4RHLA 3PZLA 3TF3A 1T4SA 3E9BA 3SL0A 2CEVA 1ZPEA 2RLAA 4IXUA 3SJTA 2EF5A 1P8OA 2A0MA 2ZAVA 1T5GA 1HQ5A 1HQXA 3NIOA 3THHA 1TBHA 2PHOA 4RHQA 1WVBA 3E8QA 3MMRA 1PQ3A 4ITYA 4IE1A 4Q3PA 4IU1A 4GSVA 4HZEA 4MYFA 1P8QA 4IE2A 3THEA 4MYKA 4GSZA 5CEVA 4Q3RA 1D3VA 1WVAA 5HJ9A 3F80A 4IU4A 1ZPGA 4MXRA 4GWDA 4Q41A 1TA1A 1HQFA 1P8MA 1P8RA 2PHAA 1TBJA 3NIQA 4I06A 4HXQA 4Q40A 3THJA 3SKKA 4Q3VA 1WOIA 3SL1A 1T4RA 1GQ6A 4Q3SA 3E8ZA 4DZ4A 4GWCA 1WOHA 3MJLA 4IE3A 3MFVA 3RLAA 4RHKA 4Q3QA 3CEVA 3E6VA 4CEVA 4IU0A 2EIVA 3E6KA 1T4TA 1XFKA 4FCIA 4RHJA 4Q3UA 3NIPA 4GSMA 3GMZA 1WOGA 4G3HA 2AEBA 4MYNA 3TH7A 1P8PA 4RLAA 2PLLA 3GN0A 1P8NA 3KV2A 1P8SA 3LP7A 4IU5A 4IXVA
chains in the Genus database with same CATH superfamily
1T67A 2VQVA 5G0JA 4Q3RC 4CQFA 1R1OA 4LY1A 1T4PA 4ZUNA 1T5FA 4ZUOA 1W22A 1HQGA 1T69A 1CEVA 3M1RA 3LHLA 4HWWA 5EENA 4BZ7A 1RLAA 5G3WA 2EF4A 5EF8A 3ZNSA 1HQHA 5RLAA 5DC8A 5D1CA 4RHIA 4CBYA 3C0YA 3EWFA 4Q3TA 3MFWA 4RHMA 5EFNA 5HJAA 1C3PA 1TBLA 3DJ8A 3LP4A 3Q9CA 5ICNB 5EFJD 4Q42A 4MYLA 3MZ4A 4FCKA 1GQ7A 4BZ6A 3Q9FA 5EF7A 4A69A 4RHLA 2VCGA 3F0RA 3PZLA 4BZ5A 3MAXA 3TF3A 1T4SA 4RN2A 3ZNRA 5G0GA 3E9BA 3SL0A 2CEVA 4QA3A 2VQMA 5IWGA 5IX0A 2VQQA 3MENA 4BZ8A 1ZPEA 2RLAA 3MZ3A 4IXUA 5FUEA 3SJTA 5EFKB 2EF5A 5JI5A 1P8OA 2A0MA 2ZAVA 1T5GA 1HQ5A 1HQXA 3NIOA 3THHA 1TBHA 3C0ZA 3EZTA 2PHOA 4RHQA 1WVBA 3E8QA 1ZZ1A 4RN1A 5G0YA 3SFFA 5G12A 5BWZA 3MMRA 1PQ3A 4ITYA 4IE1A 4Q3PA 4IU1A 4GSVA 4HZEA 4QA7A 4MYFA 1P8QA 4IE2A 4ZUMA 4MYKA 3THEA 5A2SA 5G17A 3MZ6A 5EFHA 4GSZA 5CEVA 3Q9BA 5EFGA 5G0XA 5THTA 4Q3RA 5DC7A 2GH6A 5DC6A 1D3VA 1WVAA 5G1AA 5HJ9A 3F80A 4IU4A 1ZPGA 4MXRA 2V5XA 4GWDA 4Q41A 1TA1A 1HQFA 1P8MA 1P8RA 5G13A 2VQJA 5EEKA 4QA5A 2PHAA 5G1BA 1TBJA 4QA6A 4RN0A 4ZUQA 3NIQA 4I06A 4HXQA 5EFBD 4Q40A 3THJA 4QA1A 3SKKA 2V5WA 5G0IA 5LI3A 4Q3VA 1WOIA 4QA2A 4ZURA 3SL1A 1T4RA 1GQ6A 4Q3SA 1C3SA 3E8ZA 4QA4A 5EEMA 1C3RA 5THSA 4DZ4A 3Q9EA 4GWCA 5EEIA 1WOHA 4CBTA 3MJLA 4IE3A 3MFVA 3MZ7A 5DC5A 3RLAA 5D1BA 4RHKA 4Q3QA 5THVA 3CEVA 3E6VA 4CEVA 5G1CA 5THUA 4IU0A 2EIVA 2VQWG 3E6KA 4QA0A 3SFHA 4BZ9A 1T4TA 1XFKA 3F06A 4ZUPA 4FCIA 3F07A 4RHJA 4Q3UA 3NIPA 4GSMA 3GMZA 4LXZA 5G11A 4BKXB 5G0HA 1WOGA 4G3HA 3C10A 2VQOA 2AEBA 4MYNA 3TH7A 1ZZ3A 1P8PA 4RLAA 2PLLA 3GN0A 1T64A 5D1DA 1P8NA 3KV2A 3EW8A 3EZPA 1ZZ0A 5FCWA 1P8SA 1VKGA 5G10A 3LP7A 5EEFA 3RQDA 4IU5A 4IXVA
chains in the Genus database with same CATH topology
4Q3RC 1R1OA 1T4PA 1T5FA 1HQGA 1CEVA 3M1RA 3LHLA 4HWWA 1RLAA 2EF4A 1HQHA 5RLAA 4RHIA 4RHMA 4Q3TA 3MFWA 5HJAA 1TBLA 3DJ8A 3LP4A 4Q42A 4MYLA 4FCKA 1GQ7A 4RHLA 3PZLA 3TF3A 1T4SA 3E9BA 3SL0A 2CEVA 1ZPEA 2RLAA 4IXUA 3SJTA 2EF5A 1P8OA 2A0MA 2ZAVA 1T5GA 1HQ5A 1HQXA 3NIOA 3THHA 1TBHA 2PHOA 4RHQA 1WVBA 3E8QA 3MMRA 1PQ3A 4ITYA 4IE1A 4Q3PA 4IU1A 4GSVA 4HZEA 4MYFA 1P8QA 4IE2A 3THEA 4MYKA 4GSZA 5CEVA 4Q3RA 1D3VA 1WVAA 5HJ9A 3F80A 4IU4A 1ZPGA 4MXRA 4GWDA 4Q41A 1TA1A 1HQFA 1P8MA 1P8RA 2PHAA 1TBJA 3NIQA 4I06A 4HXQA 4Q40A 3THJA 3SKKA 4Q3VA 1WOIA 3SL1A 1T4RA 1GQ6A 4Q3SA 3E8ZA 4DZ4A 4GWCA 1WOHA 3MJLA 4IE3A 3MFVA 3RLAA 4RHKA 4Q3QA 3CEVA 3E6VA 4CEVA 4IU0A 2EIVA 3E6KA 1T4TA 1XFKA 4FCIA 4RHJA 4Q3UA 3NIPA 4GSMA 3GMZA 1WOGA 4G3HA 2AEBA 4MYNA 3TH7A 1P8PA 4RLAA 2PLLA 3GN0A 1P8NA 3KV2A 1P8SA 3LP7A 4IU5A 4IXVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q3R C;  1R1O A;  1T4P A;  1T5F A;  1HQG A;  1CEV A;  3M1R A;  3LHL A;  4HWW A;  1RLA A;  2EF4 A;  1HQH A;  5RLA A;  4RHI A;  4RHM A;  4Q3T A;  3MFW A;  5HJA A;  1TBL A;  3DJ8 A;  3LP4 A;  4Q42 A;  4MYL A;  4FCK A;  1GQ7 A;  4RHL A;  3PZL A;  3TF3 A;  1T4S A;  3E9B A;  3SL0 A;  2CEV A;  1ZPE A;  2RLA A;  4IXU A;  3SJT A;  2EF5 A;  1P8O A;  2A0M A;  2ZAV A;  1T5G A;  1HQ5 A;  1HQX A;  3NIO A;  3THH A;  1TBH A;  2PHO A;  4RHQ A;  1WVB A;  3E8Q A;  3MMR A;  1PQ3 A;  4ITY A;  4IE1 A;  4Q3P A;  4IU1 A;  4GSV A;  4HZE A;  4MYF A;  1P8Q A;  4IE2 A;  3THE A;  4MYK A;  4GSZ A;  5CEV A;  4Q3R A;  1D3V A;  1WVA A;  5HJ9 A;  3F80 A;  4IU4 A;  1ZPG A;  4MXR A;  4GWD A;  4Q41 A;  1TA1 A;  1HQF A;  1P8M A;  1P8R A;  2PHA A;  1TBJ A;  3NIQ A;  4I06 A;  4HXQ A;  4Q40 A;  3THJ A;  3SKK A;  4Q3V A;  1WOI A;  3SL1 A;  1T4R A;  1GQ6 A;  4Q3S A;  3E8Z A;  4DZ4 A;  4GWC A;  1WOH A;  3MJL A;  4IE3 A;  3MFV A;  3RLA A;  4RHK A;  4Q3Q A;  3CEV A;  3E6V A;  4CEV A;  4IU0 A;  2EIV A;  3E6K A;  1T4T A;  1XFK A;  4FCI A;  4RHJ A;  4Q3U A;  3NIP A;  4GSM A;  3GMZ A;  1WOG A;  4G3H A;  2AEB A;  4MYN A;  3TH7 A;  1P8P A;  4RLA A;  2PLL A;  3GN0 A;  1P8N A;  3KV2 A;  1P8S A;  3LP7 A;  4IU5 A;  4IXV A; 
#chains in the Genus database with same CATH topology
 1T67 A;  2VQV A;  5G0J A;  4Q3R C;  4CQF A;  1R1O A;  4LY1 A;  1T4P A;  4ZUN A;  1T5F A;  4ZUO A;  1W22 A;  1HQG A;  1T69 A;  1CEV A;  3M1R A;  3LHL A;  4HWW A;  5EEN A;  4BZ7 A;  1RLA A;  5G3W A;  2EF4 A;  5EF8 A;  3ZNS A;  1HQH A;  5RLA A;  5DC8 A;  5D1C A;  4RHI A;  4CBY A;  3C0Y A;  3EWF A;  4Q3T A;  3MFW A;  4RHM A;  5EFN A;  5HJA A;  1C3P A;  1TBL A;  3DJ8 A;  3LP4 A;  3Q9C A;  5ICN B;  5EFJ D;  4Q42 A;  4MYL A;  3MZ4 A;  4FCK A;  1GQ7 A;  4BZ6 A;  3Q9F A;  5EF7 A;  4A69 A;  4RHL A;  2VCG A;  3F0R A;  3PZL A;  4BZ5 A;  3MAX A;  3TF3 A;  1T4S A;  4RN2 A;  3ZNR A;  5G0G A;  3E9B A;  3SL0 A;  2CEV A;  4QA3 A;  2VQM A;  5IWG A;  5IX0 A;  2VQQ A;  3MEN A;  4BZ8 A;  1ZPE A;  2RLA A;  3MZ3 A;  4IXU A;  5FUE A;  3SJT A;  5EFK B;  2EF5 A;  5JI5 A;  1P8O A;  2A0M A;  2ZAV A;  1T5G A;  1HQ5 A;  1HQX A;  3NIO A;  3THH A;  1TBH A;  3C0Z A;  3EZT A;  2PHO A;  4RHQ A;  1WVB A;  3E8Q A;  1ZZ1 A;  4RN1 A;  5G0Y A;  3SFF A;  5G12 A;  5BWZ A;  3MMR A;  1PQ3 A;  4ITY A;  4IE1 A;  4Q3P A;  4IU1 A;  4GSV A;  4HZE A;  4QA7 A;  4MYF A;  1P8Q A;  4IE2 A;  4ZUM A;  4MYK A;  3THE A;  5A2S A;  5G17 A;  3MZ6 A;  5EFH A;  4GSZ A;  5CEV A;  3Q9B A;  5EFG A;  5G0X A;  5THT A;  4Q3R A;  5DC7 A;  2GH6 A;  5DC6 A;  1D3V A;  1WVA A;  5G1A A;  5HJ9 A;  3F80 A;  4IU4 A;  1ZPG A;  4MXR A;  2V5X A;  4GWD A;  4Q41 A;  1TA1 A;  1HQF A;  1P8M A;  1P8R A;  5G13 A;  2VQJ A;  5EEK A;  4QA5 A;  2PHA A;  5G1B A;  1TBJ A;  4QA6 A;  4RN0 A;  4ZUQ A;  3NIQ A;  4I06 A;  4HXQ A;  5EFB D;  4Q40 A;  3THJ A;  4QA1 A;  3SKK A;  2V5W A;  5G0I A;  5LI3 A;  4Q3V A;  1WOI A;  4QA2 A;  4ZUR A;  3SL1 A;  1T4R A;  1GQ6 A;  4Q3S A;  1C3S A;  3E8Z A;  4QA4 A;  5EEM A;  1C3R A;  5THS A;  4DZ4 A;  3Q9E A;  4GWC A;  5EEI A;  1WOH A;  4CBT A;  3MJL A;  4IE3 A;  3MFV A;  3MZ7 A;  5DC5 A;  3RLA A;  5D1B A;  4RHK A;  4Q3Q A;  5THV A;  3CEV A;  3E6V A;  4CEV A;  5G1C A;  5THU A;  4IU0 A;  2EIV A;  2VQW G;  3E6K A;  4QA0 A;  3SFH A;  4BZ9 A;  1T4T A;  1XFK A;  3F06 A;  4ZUP A;  4FCI A;  3F07 A;  4RHJ A;  4Q3U A;  3NIP A;  4GSM A;  3GMZ A;  4LXZ A;  5G11 A;  4BKX B;  5G0H A;  1WOG A;  4G3H A;  3C10 A;  2VQO A;  2AEB A;  4MYN A;  3TH7 A;  1ZZ3 A;  1P8P A;  4RLA A;  2PLL A;  3GN0 A;  1T64 A;  5D1D A;  1P8N A;  3KV2 A;  3EW8 A;  3EZP A;  1ZZ0 A;  5FCW A;  1P8S A;  1VKG A;  5G10 A;  3LP7 A;  5EEF A;  3RQD A;  4IU5 A;  4IXV A; 
#chains in the Genus database with same CATH homology
 4Q3R C;  1R1O A;  1T4P A;  1T5F A;  1HQG A;  1CEV A;  3M1R A;  3LHL A;  4HWW A;  1RLA A;  2EF4 A;  1HQH A;  5RLA A;  4RHI A;  4RHM A;  4Q3T A;  3MFW A;  5HJA A;  1TBL A;  3DJ8 A;  3LP4 A;  4Q42 A;  4MYL A;  4FCK A;  1GQ7 A;  4RHL A;  3PZL A;  3TF3 A;  1T4S A;  3E9B A;  3SL0 A;  2CEV A;  1ZPE A;  2RLA A;  4IXU A;  3SJT A;  2EF5 A;  1P8O A;  2A0M A;  2ZAV A;  1T5G A;  1HQ5 A;  1HQX A;  3NIO A;  3THH A;  1TBH A;  2PHO A;  4RHQ A;  1WVB A;  3E8Q A;  3MMR A;  1PQ3 A;  4ITY A;  4IE1 A;  4Q3P A;  4IU1 A;  4GSV A;  4HZE A;  4MYF A;  1P8Q A;  4IE2 A;  3THE A;  4MYK A;  4GSZ A;  5CEV A;  4Q3R A;  1D3V A;  1WVA A;  5HJ9 A;  3F80 A;  4IU4 A;  1ZPG A;  4MXR A;  4GWD A;  4Q41 A;  1TA1 A;  1HQF A;  1P8M A;  1P8R A;  2PHA A;  1TBJ A;  3NIQ A;  4I06 A;  4HXQ A;  4Q40 A;  3THJ A;  3SKK A;  4Q3V A;  1WOI A;  3SL1 A;  1T4R A;  1GQ6 A;  4Q3S A;  3E8Z A;  4DZ4 A;  4GWC A;  1WOH A;  3MJL A;  4IE3 A;  3MFV A;  3RLA A;  4RHK A;  4Q3Q A;  3CEV A;  3E6V A;  4CEV A;  4IU0 A;  2EIV A;  3E6K A;  1T4T A;  1XFK A;  4FCI A;  4RHJ A;  4Q3U A;  3NIP A;  4GSM A;  3GMZ A;  1WOG A;  4G3H A;  2AEB A;  4MYN A;  3TH7 A;  1P8P A;  4RLA A;  2PLL A;  3GN0 A;  1P8N A;  3KV2 A;  1P8S A;  3LP7 A;  4IU5 A;  4IXV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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