2ZAVA

Arginase i (homo sapiens): native and unliganded structure at 1.70 a resolution
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 117
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2007-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 2zavA00
3E8QA 1WOGA 1R1OA 1CEVA 1TA1A 2CEVA 4I06A 3THJA 1ZPGA 3LHLA 3NIQA 3MJLA 1HQFA 3LP7A 4GWDA 2EF4A 3THEA 4FCIA 3TF3A 4Q3SA 3THHA 3PZLA 3SL1A 4RHLA 1P8SA 4Q42A 2EIVA 3TH7A 1PQ3A 3MFWA 4MYNA 4MXRA 1T4SA 4RHKA 4HXQA 2AEBA 1HQHA 1WVAA 4HWWA 1ZPEA 1WVBA 1XFKA 4RHIA 4FCKA 4RHMA 1P8MA 3E6VA 3E9BA 3GN0A 4CEVA 4Q41A 4Q3RC 1P8PA 1T4RA 4RHQA 1RLAA 2EF5A 4IE3A 4IXUA 4MYFA 1T4TA 2RLAA 4G3HA 3NIOA 4Q3VA 1HQGA 3RLAA 1TBLA 3KV2A 4IU0A 4RHJA 1P8RA 1WOHA 4ITYA 3SJTA 4DZ4A 4GSVA 4Q3QA 3MFVA 4IU1A 3M1RA 1HQ5A 4IU5A 4GWCA 1TBJA 3E6KA 4Q3UA 4Q3RA 5CEVA 4GSMA 1D3VA 1T4PA 1HQXA 1WOIA 4Q40A 2A0MA 3SKKA 1TBHA 4MYLA 5HJ9A 1T5GA 1T5FA 3DJ8A 3CEVA 3E8ZA 4Q3TA 4Q3PA 3SL0A 3LP4A 4IU4A 2ZAVA 2PLLA 1P8NA 5HJAA 1P8OA 3F80A 4IE1A 4IXVA 3GMZA 4HZEA 4MYKA 5RLAA 1GQ7A 4RLAA 3NIPA 2PHAA 2PHOA 3MMRA 1P8QA 4GSZA 4IE2A 1GQ6A
chains in the Genus database with same CATH superfamily
5G3WA 3E8QA 1WOGA 1R1OA 1CEVA 4BKXB 1TA1A 2CEVA 4I06A 3F0RA 4QA3A 5EF8A 3SFHA 3THJA 1ZPGA 3LHLA 3NIQA 3MJLA 4ZUQA 4LY1A 5EEMA 4LXZA 1HQFA 3F06A 3LP7A 5EENA 5G0GA 4GWDA 2EF4A 4QA5A 4BZ9A 3MZ7A 1VKGA 5G0YA 4FCIA 3THEA 4QA1A 3TF3A 4Q3SA 3THHA 3PZLA 3SL1A 4RHLA 1P8SA 3MZ3A 4Q42A 2EIVA 5G1AA 5G1BA 3TH7A 1PQ3A 3MFWA 3Q9FA 4MYNA 4MXRA 5G1CA 1T4SA 4RHKA 4HXQA 2AEBA 1HQHA 1WVAA 5JI5A 3Q9CA 4HWWA 1ZPEA 4CBYA 1WVBA 5G12A 1XFKA 4RHIA 4FCKA 5EEKA 1T64A 3EW8A 3EZPA 3F07A 4RHMA 5G13A 4BZ8A 1P8MA 3C10A 3E6VA 3E9BA 3GN0A 2VQMA 3EZTA 5G0XA 5IWGA 4CEVA 4Q41A 4Q3RC 1P8PA 1T4RA 1ZZ3A 4RHQA 1RLAA 4RN2A 5THSA 4ZUPA 5THUA 5D1BA 5G0IA 2EF5A 4IE3A 4CBTA 2V5XA 4IXUA 4MYFA 3C0ZA 5D1DA 1T4TA 3Q9BA 5G0HA 3ZNRA 1ZZ0A 2RLAA 4G3HA 3NIOA 4CQFA 4Q3VA 2GH6A 1HQGA 3MZ4A 3MAXA 1C3SA 3RLAA 4ZUNA 1TBLA 3KV2A 4IU0A 5EEIA 5G10A 1ZZ1A 3C0YA 5THVA 4QA6A 5EF7A 4RHJA 4QA0A 1P8RA 1WOHA 3EWFA 4ITYA 2VCGA 5DC5A 4ZUOA 4RN1A 3SJTA 4BZ7A 5A2SA 5EFGA 3MZ6A 5LI3A 5EEFA 4DZ4A 4GSVA 4Q3QA 4RN0A 3MFVA 4IU1A 3M1RA 1HQ5A 5EFHA 4IU5A 2VQVA 4GWCA 1T67A 1TBJA 3E6KA 4Q3UA 4Q3RA 5CEVA 5THTA 3ZNSA 2VQQA 5DC7A 3Q9EA 4GSMA 1D3VA 4ZUMA 2VQOA 5DC6A 1T4PA 5IX0A 1C3PA 1HQXA 1WOIA 4Q40A 5FCWA 2A0MA 5G17A 5G0JA 1TBHA 3SFFA 3SKKA 4MYLA 5HJ9A 1T5GA 1T5FA 3DJ8A 3CEVA 3E8ZA 4Q3TA 4Q3PA 5EFJD 3SL0A 3LP4A 5D1CA 4IU4A 2ZAVA 5EFBD 3RQDA 5ICNB 2PLLA 1P8NA 5HJAA 1P8OA 5DC8A 1W22A 4ZURA 3F80A 4IE1A 4IXVA 3GMZA 2V5WA 4HZEA 4MYKA 2VQJA 5FUEA 1T69A 4BZ5A 5G11A 5EFNA 5RLAA 5BWZA 1GQ7A 2VQWG 4RLAA 3NIPA 4QA7A 4QA2A 5EFKB 4BZ6A 2PHAA 2PHOA 3MMRA 1P8QA 4A69A 4GSZA 4IE2A 1GQ6A 3MENA 4QA4A 1C3RA
chains in the Genus database with same CATH topology
3E8QA 1WOGA 1R1OA 1CEVA 1TA1A 2CEVA 4I06A 3THJA 1ZPGA 3LHLA 3NIQA 3MJLA 1HQFA 3LP7A 4GWDA 2EF4A 3THEA 4FCIA 3TF3A 4Q3SA 3THHA 3PZLA 3SL1A 4RHLA 1P8SA 4Q42A 2EIVA 3TH7A 1PQ3A 3MFWA 4MYNA 4MXRA 1T4SA 4RHKA 4HXQA 2AEBA 1HQHA 1WVAA 4HWWA 1ZPEA 1WVBA 1XFKA 4RHIA 4FCKA 4RHMA 1P8MA 3E6VA 3E9BA 3GN0A 4CEVA 4Q41A 4Q3RC 1P8PA 1T4RA 4RHQA 1RLAA 2EF5A 4IE3A 4IXUA 4MYFA 1T4TA 2RLAA 4G3HA 3NIOA 4Q3VA 1HQGA 3RLAA 1TBLA 3KV2A 4IU0A 4RHJA 1P8RA 1WOHA 4ITYA 3SJTA 4DZ4A 4GSVA 4Q3QA 3MFVA 4IU1A 3M1RA 1HQ5A 4IU5A 4GWCA 1TBJA 3E6KA 4Q3UA 4Q3RA 5CEVA 4GSMA 1D3VA 1T4PA 1HQXA 1WOIA 4Q40A 2A0MA 3SKKA 1TBHA 4MYLA 5HJ9A 1T5GA 1T5FA 3DJ8A 3CEVA 3E8ZA 4Q3TA 4Q3PA 3SL0A 3LP4A 4IU4A 2ZAVA 2PLLA 1P8NA 5HJAA 1P8OA 3F80A 4IE1A 4IXVA 3GMZA 4HZEA 4MYKA 5RLAA 1GQ7A 4RLAA 3NIPA 2PHAA 2PHOA 3MMRA 1P8QA 4GSZA 4IE2A 1GQ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E8Q A;  1WOG A;  1R1O A;  1CEV A;  1TA1 A;  2CEV A;  4I06 A;  3THJ A;  1ZPG A;  3LHL A;  3NIQ A;  3MJL A;  1HQF A;  3LP7 A;  4GWD A;  2EF4 A;  3THE A;  4FCI A;  3TF3 A;  4Q3S A;  3THH A;  3PZL A;  3SL1 A;  4RHL A;  1P8S A;  4Q42 A;  2EIV A;  3TH7 A;  1PQ3 A;  3MFW A;  4MYN A;  4MXR A;  1T4S A;  4RHK A;  4HXQ A;  2AEB A;  1HQH A;  1WVA A;  4HWW A;  1ZPE A;  1WVB A;  1XFK A;  4RHI A;  4FCK A;  4RHM A;  1P8M A;  3E6V A;  3E9B A;  3GN0 A;  4CEV A;  4Q41 A;  4Q3R C;  1P8P A;  1T4R A;  4RHQ A;  1RLA A;  2EF5 A;  4IE3 A;  4IXU A;  4MYF A;  1T4T A;  2RLA A;  4G3H A;  3NIO A;  4Q3V A;  1HQG A;  3RLA A;  1TBL A;  3KV2 A;  4IU0 A;  4RHJ A;  1P8R A;  1WOH A;  4ITY A;  3SJT A;  4DZ4 A;  4GSV A;  4Q3Q A;  3MFV A;  4IU1 A;  3M1R A;  1HQ5 A;  4IU5 A;  4GWC A;  1TBJ A;  3E6K A;  4Q3U A;  4Q3R A;  5CEV A;  4GSM A;  1D3V A;  1T4P A;  1HQX A;  1WOI A;  4Q40 A;  2A0M A;  3SKK A;  1TBH A;  4MYL A;  5HJ9 A;  1T5G A;  1T5F A;  3DJ8 A;  3CEV A;  3E8Z A;  4Q3T A;  4Q3P A;  3SL0 A;  3LP4 A;  4IU4 A;  2ZAV A;  2PLL A;  1P8N A;  5HJA A;  1P8O A;  3F80 A;  4IE1 A;  4IXV A;  3GMZ A;  4HZE A;  4MYK A;  5RLA A;  1GQ7 A;  4RLA A;  3NIP A;  2PHA A;  2PHO A;  3MMR A;  1P8Q A;  4GSZ A;  4IE2 A;  1GQ6 A; 
#chains in the Genus database with same CATH topology
 5G3W A;  3E8Q A;  1WOG A;  1R1O A;  1CEV A;  4BKX B;  1TA1 A;  2CEV A;  4I06 A;  3F0R A;  4QA3 A;  5EF8 A;  3SFH A;  3THJ A;  1ZPG A;  3LHL A;  3NIQ A;  3MJL A;  4ZUQ A;  4LY1 A;  5EEM A;  4LXZ A;  1HQF A;  3F06 A;  3LP7 A;  5EEN A;  5G0G A;  4GWD A;  2EF4 A;  4QA5 A;  4BZ9 A;  3MZ7 A;  1VKG A;  5G0Y A;  4FCI A;  3THE A;  4QA1 A;  3TF3 A;  4Q3S A;  3THH A;  3PZL A;  3SL1 A;  4RHL A;  1P8S A;  3MZ3 A;  4Q42 A;  2EIV A;  5G1A A;  5G1B A;  3TH7 A;  1PQ3 A;  3MFW A;  3Q9F A;  4MYN A;  4MXR A;  5G1C A;  1T4S A;  4RHK A;  4HXQ A;  2AEB A;  1HQH A;  1WVA A;  5JI5 A;  3Q9C A;  4HWW A;  1ZPE A;  4CBY A;  1WVB A;  5G12 A;  1XFK A;  4RHI A;  4FCK A;  5EEK A;  1T64 A;  3EW8 A;  3EZP A;  3F07 A;  4RHM A;  5G13 A;  4BZ8 A;  1P8M A;  3C10 A;  3E6V A;  3E9B A;  3GN0 A;  2VQM A;  3EZT A;  5G0X A;  5IWG A;  4CEV A;  4Q41 A;  4Q3R C;  1P8P A;  1T4R A;  1ZZ3 A;  4RHQ A;  1RLA A;  4RN2 A;  5THS A;  4ZUP A;  5THU A;  5D1B A;  5G0I A;  2EF5 A;  4IE3 A;  4CBT A;  2V5X A;  4IXU A;  4MYF A;  3C0Z A;  5D1D A;  1T4T A;  3Q9B A;  5G0H A;  3ZNR A;  1ZZ0 A;  2RLA A;  4G3H A;  3NIO A;  4CQF A;  4Q3V A;  2GH6 A;  1HQG A;  3MZ4 A;  3MAX A;  1C3S A;  3RLA A;  4ZUN A;  1TBL A;  3KV2 A;  4IU0 A;  5EEI A;  5G10 A;  1ZZ1 A;  3C0Y A;  5THV A;  4QA6 A;  5EF7 A;  4RHJ A;  4QA0 A;  1P8R A;  1WOH A;  3EWF A;  4ITY A;  2VCG A;  5DC5 A;  4ZUO A;  4RN1 A;  3SJT A;  4BZ7 A;  5A2S A;  5EFG A;  3MZ6 A;  5LI3 A;  5EEF A;  4DZ4 A;  4GSV A;  4Q3Q A;  4RN0 A;  3MFV A;  4IU1 A;  3M1R A;  1HQ5 A;  5EFH A;  4IU5 A;  2VQV A;  4GWC A;  1T67 A;  1TBJ A;  3E6K A;  4Q3U A;  4Q3R A;  5CEV A;  5THT A;  3ZNS A;  2VQQ A;  5DC7 A;  3Q9E A;  4GSM A;  1D3V A;  4ZUM A;  2VQO A;  5DC6 A;  1T4P A;  5IX0 A;  1C3P A;  1HQX A;  1WOI A;  4Q40 A;  5FCW A;  2A0M A;  5G17 A;  5G0J A;  1TBH A;  3SFF A;  3SKK A;  4MYL A;  5HJ9 A;  1T5G A;  1T5F A;  3DJ8 A;  3CEV A;  3E8Z A;  4Q3T A;  4Q3P A;  5EFJ D;  3SL0 A;  3LP4 A;  5D1C A;  4IU4 A;  2ZAV A;  5EFB D;  3RQD A;  5ICN B;  2PLL A;  1P8N A;  5HJA A;  1P8O A;  5DC8 A;  1W22 A;  4ZUR A;  3F80 A;  4IE1 A;  4IXV A;  3GMZ A;  2V5W A;  4HZE A;  4MYK A;  2VQJ A;  5FUE A;  1T69 A;  4BZ5 A;  5G11 A;  5EFN A;  5RLA A;  5BWZ A;  1GQ7 A;  2VQW G;  4RLA A;  3NIP A;  4QA7 A;  4QA2 A;  5EFK B;  4BZ6 A;  2PHA A;  2PHO A;  3MMR A;  1P8Q A;  4A69 A;  4GSZ A;  4IE2 A;  1GQ6 A;  3MEN A;  4QA4 A;  1C3R A; 
#chains in the Genus database with same CATH homology
 3E8Q A;  1WOG A;  1R1O A;  1CEV A;  1TA1 A;  2CEV A;  4I06 A;  3THJ A;  1ZPG A;  3LHL A;  3NIQ A;  3MJL A;  1HQF A;  3LP7 A;  4GWD A;  2EF4 A;  3THE A;  4FCI A;  3TF3 A;  4Q3S A;  3THH A;  3PZL A;  3SL1 A;  4RHL A;  1P8S A;  4Q42 A;  2EIV A;  3TH7 A;  1PQ3 A;  3MFW A;  4MYN A;  4MXR A;  1T4S A;  4RHK A;  4HXQ A;  2AEB A;  1HQH A;  1WVA A;  4HWW A;  1ZPE A;  1WVB A;  1XFK A;  4RHI A;  4FCK A;  4RHM A;  1P8M A;  3E6V A;  3E9B A;  3GN0 A;  4CEV A;  4Q41 A;  4Q3R C;  1P8P A;  1T4R A;  4RHQ A;  1RLA A;  2EF5 A;  4IE3 A;  4IXU A;  4MYF A;  1T4T A;  2RLA A;  4G3H A;  3NIO A;  4Q3V A;  1HQG A;  3RLA A;  1TBL A;  3KV2 A;  4IU0 A;  4RHJ A;  1P8R A;  1WOH A;  4ITY A;  3SJT A;  4DZ4 A;  4GSV A;  4Q3Q A;  3MFV A;  4IU1 A;  3M1R A;  1HQ5 A;  4IU5 A;  4GWC A;  1TBJ A;  3E6K A;  4Q3U A;  4Q3R A;  5CEV A;  4GSM A;  1D3V A;  1T4P A;  1HQX A;  1WOI A;  4Q40 A;  2A0M A;  3SKK A;  1TBH A;  4MYL A;  5HJ9 A;  1T5G A;  1T5F A;  3DJ8 A;  3CEV A;  3E8Z A;  4Q3T A;  4Q3P A;  3SL0 A;  3LP4 A;  4IU4 A;  2ZAV A;  2PLL A;  1P8N A;  5HJA A;  1P8O A;  3F80 A;  4IE1 A;  4IXV A;  3GMZ A;  4HZE A;  4MYK A;  5RLA A;  1GQ7 A;  4RLA A;  3NIP A;  2PHA A;  2PHO A;  3MMR A;  1P8Q A;  4GSZ A;  4IE2 A;  1GQ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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