3E6KA

X-ray structure of human arginase i: the mutant d183a in complex with abh
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
308
structure length
308
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVAPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the specificity determinants of amino acid recognition by arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 106
structure length 308
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3e6kA00
4GWDA 3THJA 1ZPGA 1T4TA 1R1OA 3LHLA 4FCKA 4HZEA 4HWWA 3MFVA 1T4PA 2ZAVA 4IE2A 2EIVA 1XFKA 4Q3VA 2PHAA 1HQXA 4RHMA 3SL0A 3E8ZA 4IE1A 4MYNA 4Q40A 3NIOA 4HXQA 3CEVA 3E6VA 1HQ5A 4IXUA 3LP4A 3NIPA 3SL1A 4GSZA 1P8SA 5CEVA 1CEVA 4RHIA 4MYKA 3SKKA 4IE3A 4GSMA 4Q3TA 3NIQA 1P8QA 1T4SA 4RHQA 3MJLA 4IU5A 3KV2A 3LP7A 2AEBA 1GQ6A 3GN0A 3M1RA 1P8RA 1TBLA 1WOGA 1P8OA 4IU0A 2EF4A 4RHJA 4Q41A 2PLLA 5HJ9A 1WOIA 4IU1A 3E9BA 2CEVA 4RLAA 4Q3UA 4MXRA 4Q3PA 4Q3QA 4RHLA 3TH7A 1TA1A 1WOHA 3RLAA 3MFWA 1T5GA 4IXVA 1GQ7A 1P8PA 4ITYA 1HQHA 3TF3A 1T5FA 1HQFA 3F80A 2EF5A 2PHOA 3SJTA 5HJAA 4MYFA 4GSVA 1T4RA 1PQ3A 5RLAA 1P8MA 1TBHA 3E8QA 4G3HA 1WVAA 4Q3RC 3THHA 4CEVA 4RHKA 3GMZA 3MMRA 4IU4A 1WVBA 1D3VA 1HQGA 2A0MA 3DJ8A 1P8NA 3E6KA 1RLAA 4GWCA 4I06A 4FCIA 2RLAA 4Q3RA 4MYLA 4Q42A 1TBJA 4Q3SA 1ZPEA 4DZ4A 3THEA 3PZLA
chains in the Genus database with same CATH superfamily
4GWDA 3THJA 1ZPGA 2V5XA 1T4TA 1R1OA 3LHLA 4FCKA 4HZEA 1ZZ3A 4HWWA 3MFVA 5EEFA 1T4PA 2ZAVA 4IE2A 5A2SA 2EIVA 1XFKA 4Q3VA 3EZPA 4RN0A 2PHAA 1HQXA 3C0YA 2GH6A 4RHMA 5BWZA 5EFHA 5G1BA 3SL0A 3E8ZA 4IE1A 4MYNA 3F06A 4Q40A 3NIOA 4HXQA 1T67A 3CEVA 3E6VA 1HQ5A 4IXUA 4QA1A 5DC8A 4BKXB 3LP4A 3NIPA 1T64A 3SL1A 4GSZA 5D1BA 5THUA 1P8SA 5CEVA 5G0YA 3MZ4A 4BZ8A 4QA0A 1CEVA 4RHIA 1C3RA 4MYKA 3EW8A 3SKKA 4IE3A 1C3PA 3MZ3A 4GSMA 4QA5A 4Q3TA 5G11A 5THTA 5ICNB 4RN1A 3MZ6A 3NIQA 1P8QA 1T4SA 4RHQA 3MJLA 4A69A 4IU5A 3KV2A 3ZNRA 3LP7A 5G13A 5DC5A 3C10A 5EFBD 3F07A 4QA4A 5EEIA 1ZZ1A 3Q9CA 5FCWA 2AEBA 4QA2A 1GQ6A 3GN0A 5DC7A 3C0ZA 2VQWG 3M1RA 1P8RA 1TBLA 3F0RA 1WOGA 5IX0A 2VQQA 1P8OA 3MENA 4IU0A 5EF7A 1W22A 2EF4A 5EEKA 4RHJA 4Q41A 3SFHA 2PLLA 5HJ9A 5FUEA 1WOIA 4ZUNA 5EEMA 5G1AA 5THVA 5EFNA 4LXZA 4RN2A 4IU1A 3E9BA 2CEVA 4RLAA 2VQOA 4Q3UA 4MXRA 2VQJA 4Q3PA 4BZ9A 4Q3QA 5JI5A 4RHLA 5G0XA 3TH7A 1TA1A 1WOHA 2VQMA 3MAXA 4CQFA 3SFFA 5THSA 3RLAA 4ZUQA 3MFWA 3Q9FA 1T5GA 3EZTA 1C3SA 5G0IA 5EF8A 4IXVA 5EFJD 4CBYA 1GQ7A 1P8PA 4ITYA 5G0JA 2V5WA 1HQHA 3TF3A 1T5FA 4QA7A 5LI3A 1HQFA 3F80A 5EENA 2EF5A 3RQDA 5D1CA 3Q9BA 4QA6A 5G17A 1VKGA 2PHOA 3MZ7A 3SJTA 4BZ5A 5G0GA 5HJAA 4MYFA 5EFKB 1ZZ0A 2VQVA 1T4RA 4GSVA 4LY1A 4QA3A 3Q9EA 5EFGA 4ZUOA 1PQ3A 5RLAA 1P8MA 1TBHA 3E8QA 4G3HA 1WVAA 4Q3RC 3THHA 3ZNSA 4CEVA 4RHKA 5G0HA 5G10A 1T69A 3GMZA 4ZUPA 3MMRA 4IU4A 1WVBA 4BZ6A 4BZ7A 1D3VA 4ZUMA 1HQGA 2A0MA 3DJ8A 1P8NA 3E6KA 5G3WA 1RLAA 4GWCA 5D1DA 5DC6A 4CBTA 4I06A 4FCIA 2RLAA 5IWGA 4Q3RA 3EWFA 4MYLA 4Q42A 1TBJA 4Q3SA 4ZURA 5G1CA 1ZPEA 5G12A 4DZ4A 3THEA 3PZLA 2VCGA
chains in the Genus database with same CATH topology
4GWDA 3THJA 1ZPGA 1T4TA 1R1OA 3LHLA 4FCKA 4HZEA 4HWWA 3MFVA 1T4PA 2ZAVA 4IE2A 2EIVA 1XFKA 4Q3VA 2PHAA 1HQXA 4RHMA 3SL0A 3E8ZA 4IE1A 4MYNA 4Q40A 3NIOA 4HXQA 3CEVA 3E6VA 1HQ5A 4IXUA 3LP4A 3NIPA 3SL1A 4GSZA 1P8SA 5CEVA 1CEVA 4RHIA 4MYKA 3SKKA 4IE3A 4GSMA 4Q3TA 3NIQA 1P8QA 1T4SA 4RHQA 3MJLA 4IU5A 3KV2A 3LP7A 2AEBA 1GQ6A 3GN0A 3M1RA 1P8RA 1TBLA 1WOGA 1P8OA 4IU0A 2EF4A 4RHJA 4Q41A 2PLLA 5HJ9A 1WOIA 4IU1A 3E9BA 2CEVA 4RLAA 4Q3UA 4MXRA 4Q3PA 4Q3QA 4RHLA 3TH7A 1TA1A 1WOHA 3RLAA 3MFWA 1T5GA 4IXVA 1GQ7A 1P8PA 4ITYA 1HQHA 3TF3A 1T5FA 1HQFA 3F80A 2EF5A 2PHOA 3SJTA 5HJAA 4MYFA 4GSVA 1T4RA 1PQ3A 5RLAA 1P8MA 1TBHA 3E8QA 4G3HA 1WVAA 4Q3RC 3THHA 4CEVA 4RHKA 3GMZA 3MMRA 4IU4A 1WVBA 1D3VA 1HQGA 2A0MA 3DJ8A 1P8NA 3E6KA 1RLAA 4GWCA 4I06A 4FCIA 2RLAA 4Q3RA 4MYLA 4Q42A 1TBJA 4Q3SA 1ZPEA 4DZ4A 3THEA 3PZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GWD A;  3THJ A;  1ZPG A;  1T4T A;  1R1O A;  3LHL A;  4FCK A;  4HZE A;  4HWW A;  3MFV A;  1T4P A;  2ZAV A;  4IE2 A;  2EIV A;  1XFK A;  4Q3V A;  2PHA A;  1HQX A;  4RHM A;  3SL0 A;  3E8Z A;  4IE1 A;  4MYN A;  4Q40 A;  3NIO A;  4HXQ A;  3CEV A;  3E6V A;  1HQ5 A;  4IXU A;  3LP4 A;  3NIP A;  3SL1 A;  4GSZ A;  1P8S A;  5CEV A;  1CEV A;  4RHI A;  4MYK A;  3SKK A;  4IE3 A;  4GSM A;  4Q3T A;  3NIQ A;  1P8Q A;  1T4S A;  4RHQ A;  3MJL A;  4IU5 A;  3KV2 A;  3LP7 A;  2AEB A;  1GQ6 A;  3GN0 A;  3M1R A;  1P8R A;  1TBL A;  1WOG A;  1P8O A;  4IU0 A;  2EF4 A;  4RHJ A;  4Q41 A;  2PLL A;  5HJ9 A;  1WOI A;  4IU1 A;  3E9B A;  2CEV A;  4RLA A;  4Q3U A;  4MXR A;  4Q3P A;  4Q3Q A;  4RHL A;  3TH7 A;  1TA1 A;  1WOH A;  3RLA A;  3MFW A;  1T5G A;  4IXV A;  1GQ7 A;  1P8P A;  4ITY A;  1HQH A;  3TF3 A;  1T5F A;  1HQF A;  3F80 A;  2EF5 A;  2PHO A;  3SJT A;  5HJA A;  4MYF A;  4GSV A;  1T4R A;  1PQ3 A;  5RLA A;  1P8M A;  1TBH A;  3E8Q A;  4G3H A;  1WVA A;  4Q3R C;  3THH A;  4CEV A;  4RHK A;  3GMZ A;  3MMR A;  4IU4 A;  1WVB A;  1D3V A;  1HQG A;  2A0M A;  3DJ8 A;  1P8N A;  3E6K A;  1RLA A;  4GWC A;  4I06 A;  4FCI A;  2RLA A;  4Q3R A;  4MYL A;  4Q42 A;  1TBJ A;  4Q3S A;  1ZPE A;  4DZ4 A;  3THE A;  3PZL A; 
#chains in the Genus database with same CATH topology
 4GWD A;  3THJ A;  1ZPG A;  2V5X A;  1T4T A;  1R1O A;  3LHL A;  4FCK A;  4HZE A;  1ZZ3 A;  4HWW A;  3MFV A;  5EEF A;  1T4P A;  2ZAV A;  4IE2 A;  5A2S A;  2EIV A;  1XFK A;  4Q3V A;  3EZP A;  4RN0 A;  2PHA A;  1HQX A;  3C0Y A;  2GH6 A;  4RHM A;  5BWZ A;  5EFH A;  5G1B A;  3SL0 A;  3E8Z A;  4IE1 A;  4MYN A;  3F06 A;  4Q40 A;  3NIO A;  4HXQ A;  1T67 A;  3CEV A;  3E6V A;  1HQ5 A;  4IXU A;  4QA1 A;  5DC8 A;  4BKX B;  3LP4 A;  3NIP A;  1T64 A;  3SL1 A;  4GSZ A;  5D1B A;  5THU A;  1P8S A;  5CEV A;  5G0Y A;  3MZ4 A;  4BZ8 A;  4QA0 A;  1CEV A;  4RHI A;  1C3R A;  4MYK A;  3EW8 A;  3SKK A;  4IE3 A;  1C3P A;  3MZ3 A;  4GSM A;  4QA5 A;  4Q3T A;  5G11 A;  5THT A;  5ICN B;  4RN1 A;  3MZ6 A;  3NIQ A;  1P8Q A;  1T4S A;  4RHQ A;  3MJL A;  4A69 A;  4IU5 A;  3KV2 A;  3ZNR A;  3LP7 A;  5G13 A;  5DC5 A;  3C10 A;  5EFB D;  3F07 A;  4QA4 A;  5EEI A;  1ZZ1 A;  3Q9C A;  5FCW A;  2AEB A;  4QA2 A;  1GQ6 A;  3GN0 A;  5DC7 A;  3C0Z A;  2VQW G;  3M1R A;  1P8R A;  1TBL A;  3F0R A;  1WOG A;  5IX0 A;  2VQQ A;  1P8O A;  3MEN A;  4IU0 A;  5EF7 A;  1W22 A;  2EF4 A;  5EEK A;  4RHJ A;  4Q41 A;  3SFH A;  2PLL A;  5HJ9 A;  5FUE A;  1WOI A;  4ZUN A;  5EEM A;  5G1A A;  5THV A;  5EFN A;  4LXZ A;  4RN2 A;  4IU1 A;  3E9B A;  2CEV A;  4RLA A;  2VQO A;  4Q3U A;  4MXR A;  2VQJ A;  4Q3P A;  4BZ9 A;  4Q3Q A;  5JI5 A;  4RHL A;  5G0X A;  3TH7 A;  1TA1 A;  1WOH A;  2VQM A;  3MAX A;  4CQF A;  3SFF A;  5THS A;  3RLA A;  4ZUQ A;  3MFW A;  3Q9F A;  1T5G A;  3EZT A;  1C3S A;  5G0I A;  5EF8 A;  4IXV A;  5EFJ D;  4CBY A;  1GQ7 A;  1P8P A;  4ITY A;  5G0J A;  2V5W A;  1HQH A;  3TF3 A;  1T5F A;  4QA7 A;  5LI3 A;  1HQF A;  3F80 A;  5EEN A;  2EF5 A;  3RQD A;  5D1C A;  3Q9B A;  4QA6 A;  5G17 A;  1VKG A;  2PHO A;  3MZ7 A;  3SJT A;  4BZ5 A;  5G0G A;  5HJA A;  4MYF A;  5EFK B;  1ZZ0 A;  2VQV A;  1T4R A;  4GSV A;  4LY1 A;  4QA3 A;  3Q9E A;  5EFG A;  4ZUO A;  1PQ3 A;  5RLA A;  1P8M A;  1TBH A;  3E8Q A;  4G3H A;  1WVA A;  4Q3R C;  3THH A;  3ZNS A;  4CEV A;  4RHK A;  5G0H A;  5G10 A;  1T69 A;  3GMZ A;  4ZUP A;  3MMR A;  4IU4 A;  1WVB A;  4BZ6 A;  4BZ7 A;  1D3V A;  4ZUM A;  1HQG A;  2A0M A;  3DJ8 A;  1P8N A;  3E6K A;  5G3W A;  1RLA A;  4GWC A;  5D1D A;  5DC6 A;  4CBT A;  4I06 A;  4FCI A;  2RLA A;  5IWG A;  4Q3R A;  3EWF A;  4MYL A;  4Q42 A;  1TBJ A;  4Q3S A;  4ZUR A;  5G1C A;  1ZPE A;  5G12 A;  4DZ4 A;  3THE A;  3PZL A;  2VCG A; 
#chains in the Genus database with same CATH homology
 4GWD A;  3THJ A;  1ZPG A;  1T4T A;  1R1O A;  3LHL A;  4FCK A;  4HZE A;  4HWW A;  3MFV A;  1T4P A;  2ZAV A;  4IE2 A;  2EIV A;  1XFK A;  4Q3V A;  2PHA A;  1HQX A;  4RHM A;  3SL0 A;  3E8Z A;  4IE1 A;  4MYN A;  4Q40 A;  3NIO A;  4HXQ A;  3CEV A;  3E6V A;  1HQ5 A;  4IXU A;  3LP4 A;  3NIP A;  3SL1 A;  4GSZ A;  1P8S A;  5CEV A;  1CEV A;  4RHI A;  4MYK A;  3SKK A;  4IE3 A;  4GSM A;  4Q3T A;  3NIQ A;  1P8Q A;  1T4S A;  4RHQ A;  3MJL A;  4IU5 A;  3KV2 A;  3LP7 A;  2AEB A;  1GQ6 A;  3GN0 A;  3M1R A;  1P8R A;  1TBL A;  1WOG A;  1P8O A;  4IU0 A;  2EF4 A;  4RHJ A;  4Q41 A;  2PLL A;  5HJ9 A;  1WOI A;  4IU1 A;  3E9B A;  2CEV A;  4RLA A;  4Q3U A;  4MXR A;  4Q3P A;  4Q3Q A;  4RHL A;  3TH7 A;  1TA1 A;  1WOH A;  3RLA A;  3MFW A;  1T5G A;  4IXV A;  1GQ7 A;  1P8P A;  4ITY A;  1HQH A;  3TF3 A;  1T5F A;  1HQF A;  3F80 A;  2EF5 A;  2PHO A;  3SJT A;  5HJA A;  4MYF A;  4GSV A;  1T4R A;  1PQ3 A;  5RLA A;  1P8M A;  1TBH A;  3E8Q A;  4G3H A;  1WVA A;  4Q3R C;  3THH A;  4CEV A;  4RHK A;  3GMZ A;  3MMR A;  4IU4 A;  1WVB A;  1D3V A;  1HQG A;  2A0M A;  3DJ8 A;  1P8N A;  3E6K A;  1RLA A;  4GWC A;  4I06 A;  4FCI A;  2RLA A;  4Q3R A;  4MYL A;  4Q42 A;  1TBJ A;  4Q3S A;  1ZPE A;  4DZ4 A;  3THE A;  3PZL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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