3E6VA

X-ray structure of human arginase i-d183n mutant: the complex with abh
Total Genus 115
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVNPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Probing the specificity determinants of amino acid recognition by arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 115
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3e6vA00
1GQ7A 3MFWA 5RLAA 1WOHA 4IE1A 1P8OA 2PLLA 4RHJA 1T4SA 4IU1A 4IU0A 4FCIA 4Q3RA 3GMZA 2PHAA 4HXQA 1XFKA 4IXVA 1HQXA 4Q3UA 4RHQA 3SJTA 1P8QA 4MYNA 4G3HA 3E6KA 3NIOA 1WVBA 3TH7A 1P8NA 2CEVA 3M1RA 4Q3VA 5HJAA 3GN0A 3E9BA 4FCKA 1P8RA 2EIVA 2EF5A 1ZPEA 1WVAA 4Q3QA 1HQFA 3MMRA 3E6VA 2ZAVA 4Q40A 1D3VA 2PHOA 4RHMA 3MJLA 3E8ZA 4IXUA 1HQHA 1T4TA 4RLAA 3CEVA 4HWWA 1TBJA 3THHA 1ZPGA 1WOGA 4Q3PA 4DZ4A 4Q3TA 4RHLA 2AEBA 1R1OA 3PZLA 3NIQA 4I06A 3SL0A 3DJ8A 4MXRA 1P8PA 1T5FA 2EF4A 3SKKA 1T4RA 1P8MA 4RHKA 3LP7A 1P8SA 3MFVA 4GWDA 4IE2A 1CEVA 4GSVA 2RLAA 4HZEA 4IE3A 3TF3A 3E8QA 4MYKA 3F80A 4GSMA 1T5GA 4MYFA 4GSZA 3RLAA 4ITYA 5CEVA 2A0MA 4IU4A 5HJ9A 3THEA 4CEVA 1TBLA 1TBHA 3KV2A 4Q42A 4GWCA 3SL1A 1WOIA 1HQGA 4MYLA 3THJA 4Q41A 1GQ6A 1HQ5A 4Q3RC 1T4PA 4IU5A 1RLAA 3LP4A 3NIPA 1PQ3A 3LHLA 4RHIA 1TA1A 4Q3SA
chains in the Genus database with same CATH superfamily
1GQ7A 3MFWA 5FCWA 5G0GA 5RLAA 5BWZA 1W22A 1WOHA 4IE1A 4BZ6A 1P8OA 2PLLA 5THTA 2GH6A 4RHJA 5G10A 5EEMA 1T4SA 3MZ4A 4IU1A 4IU0A 3MENA 4FCIA 5G17A 5THVA 3C10A 4Q3RA 3GMZA 3ZNRA 5A2SA 2PHAA 4HXQA 5FUEA 4QA7A 4QA0A 4QA1A 1XFKA 5EENA 4IXVA 1HQXA 3C0YA 5G1CA 5DC5A 5EFNA 5IX0A 4Q3UA 4A69A 4BZ8A 4ZUPA 4RHQA 2VQMA 1T69A 5IWGA 3SJTA 1P8QA 5EEIA 5G1AA 4MYNA 1VKGA 4G3HA 3E6KA 3NIOA 5EFJD 1WVBA 2VQQA 3TH7A 1P8NA 3SFHA 2CEVA 3M1RA 5D1BA 4Q3VA 5EF8A 5ICNB 4QA6A 5HJAA 3GN0A 4RN2A 3E9BA 4FCKA 1P8RA 2EIVA 2EF5A 5EFHA 1ZPEA 1WVAA 2VQVA 4Q3QA 1HQFA 5THUA 2VCGA 3MMRA 3E6VA 2ZAVA 4RN0A 4Q40A 1C3RA 1D3VA 2PHOA 1ZZ1A 5G11A 4RHMA 4ZUQA 1T67A 5D1DA 3MJLA 3F06A 3E8ZA 3Q9BA 5G0IA 3EWFA 4IXUA 1HQHA 1T4TA 1C3SA 3EW8A 4RLAA 3CEVA 4HWWA 4LY1A 1TBJA 5G0HA 3THHA 1ZPGA 4CQFA 1WOGA 4Q3PA 4CBYA 4DZ4A 4Q3TA 4RHLA 2AEBA 1R1OA 1T64A 3PZLA 1ZZ0A 3NIQA 4BZ7A 4I06A 3C0ZA 3SL0A 3DJ8A 4MXRA 1P8PA 4QA2A 5G1BA 4ZUMA 3EZTA 5DC8A 2V5XA 5DC7A 5G0YA 1T5FA 3MAXA 5EF7A 2EF4A 3SKKA 2VQWG 1T4RA 1P8MA 4RHKA 3LP7A 5EEKA 4QA4A 1P8SA 4BZ5A 5LI3A 4LXZA 3MFVA 4GWDA 4IE2A 5D1CA 1CEVA 2VQOA 4GSVA 2RLAA 5EFGA 4HZEA 4IE3A 4QA5A 3MZ7A 3TF3A 3E8QA 4MYKA 1ZZ3A 3EZPA 3F0RA 3F80A 4QA3A 4GSMA 5EFBD 4RN1A 1T5GA 4ZUNA 4ZURA 3MZ3A 5G0XA 5G3WA 3Q9EA 4MYFA 4GSZA 5EEFA 4CBTA 2VQJA 3ZNSA 3SFFA 3RLAA 4ITYA 5CEVA 2A0MA 3Q9CA 4IU4A 5HJ9A 3THEA 4BZ9A 4CEVA 1TBLA 1TBHA 3KV2A 3MZ6A 4Q42A 4BKXB 4GWCA 5DC6A 3SL1A 1WOIA 1HQGA 4MYLA 5G12A 3THJA 1C3PA 4Q41A 1GQ6A 1HQ5A 2V5WA 4ZUOA 4Q3RC 3RQDA 5JI5A 1T4PA 4IU5A 3Q9FA 1RLAA 3LP4A 3F07A 3NIPA 5THSA 5EFKB 5G13A 1PQ3A 3LHLA 4RHIA 1TA1A 4Q3SA 5G0JA
chains in the Genus database with same CATH topology
1GQ7A 3MFWA 5RLAA 1WOHA 4IE1A 1P8OA 2PLLA 4RHJA 1T4SA 4IU1A 4IU0A 4FCIA 4Q3RA 3GMZA 2PHAA 4HXQA 1XFKA 4IXVA 1HQXA 4Q3UA 4RHQA 3SJTA 1P8QA 4MYNA 4G3HA 3E6KA 3NIOA 1WVBA 3TH7A 1P8NA 2CEVA 3M1RA 4Q3VA 5HJAA 3GN0A 3E9BA 4FCKA 1P8RA 2EIVA 2EF5A 1ZPEA 1WVAA 4Q3QA 1HQFA 3MMRA 3E6VA 2ZAVA 4Q40A 1D3VA 2PHOA 4RHMA 3MJLA 3E8ZA 4IXUA 1HQHA 1T4TA 4RLAA 3CEVA 4HWWA 1TBJA 3THHA 1ZPGA 1WOGA 4Q3PA 4DZ4A 4Q3TA 4RHLA 2AEBA 1R1OA 3PZLA 3NIQA 4I06A 3SL0A 3DJ8A 4MXRA 1P8PA 1T5FA 2EF4A 3SKKA 1T4RA 1P8MA 4RHKA 3LP7A 1P8SA 3MFVA 4GWDA 4IE2A 1CEVA 4GSVA 2RLAA 4HZEA 4IE3A 3TF3A 3E8QA 4MYKA 3F80A 4GSMA 1T5GA 4MYFA 4GSZA 3RLAA 4ITYA 5CEVA 2A0MA 4IU4A 5HJ9A 3THEA 4CEVA 1TBLA 1TBHA 3KV2A 4Q42A 4GWCA 3SL1A 1WOIA 1HQGA 4MYLA 3THJA 4Q41A 1GQ6A 1HQ5A 4Q3RC 1T4PA 4IU5A 1RLAA 3LP4A 3NIPA 1PQ3A 3LHLA 4RHIA 1TA1A 4Q3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GQ7 A;  3MFW A;  5RLA A;  1WOH A;  4IE1 A;  1P8O A;  2PLL A;  4RHJ A;  1T4S A;  4IU1 A;  4IU0 A;  4FCI A;  4Q3R A;  3GMZ A;  2PHA A;  4HXQ A;  1XFK A;  4IXV A;  1HQX A;  4Q3U A;  4RHQ A;  3SJT A;  1P8Q A;  4MYN A;  4G3H A;  3E6K A;  3NIO A;  1WVB A;  3TH7 A;  1P8N A;  2CEV A;  3M1R A;  4Q3V A;  5HJA A;  3GN0 A;  3E9B A;  4FCK A;  1P8R A;  2EIV A;  2EF5 A;  1ZPE A;  1WVA A;  4Q3Q A;  1HQF A;  3MMR A;  3E6V A;  2ZAV A;  4Q40 A;  1D3V A;  2PHO A;  4RHM A;  3MJL A;  3E8Z A;  4IXU A;  1HQH A;  1T4T A;  4RLA A;  3CEV A;  4HWW A;  1TBJ A;  3THH A;  1ZPG A;  1WOG A;  4Q3P A;  4DZ4 A;  4Q3T A;  4RHL A;  2AEB A;  1R1O A;  3PZL A;  3NIQ A;  4I06 A;  3SL0 A;  3DJ8 A;  4MXR A;  1P8P A;  1T5F A;  2EF4 A;  3SKK A;  1T4R A;  1P8M A;  4RHK A;  3LP7 A;  1P8S A;  3MFV A;  4GWD A;  4IE2 A;  1CEV A;  4GSV A;  2RLA A;  4HZE A;  4IE3 A;  3TF3 A;  3E8Q A;  4MYK A;  3F80 A;  4GSM A;  1T5G A;  4MYF A;  4GSZ A;  3RLA A;  4ITY A;  5CEV A;  2A0M A;  4IU4 A;  5HJ9 A;  3THE A;  4CEV A;  1TBL A;  1TBH A;  3KV2 A;  4Q42 A;  4GWC A;  3SL1 A;  1WOI A;  1HQG A;  4MYL A;  3THJ A;  4Q41 A;  1GQ6 A;  1HQ5 A;  4Q3R C;  1T4P A;  4IU5 A;  1RLA A;  3LP4 A;  3NIP A;  1PQ3 A;  3LHL A;  4RHI A;  1TA1 A;  4Q3S A; 
#chains in the Genus database with same CATH topology
 1GQ7 A;  3MFW A;  5FCW A;  5G0G A;  5RLA A;  5BWZ A;  1W22 A;  1WOH A;  4IE1 A;  4BZ6 A;  1P8O A;  2PLL A;  5THT A;  2GH6 A;  4RHJ A;  5G10 A;  5EEM A;  1T4S A;  3MZ4 A;  4IU1 A;  4IU0 A;  3MEN A;  4FCI A;  5G17 A;  5THV A;  3C10 A;  4Q3R A;  3GMZ A;  3ZNR A;  5A2S A;  2PHA A;  4HXQ A;  5FUE A;  4QA7 A;  4QA0 A;  4QA1 A;  1XFK A;  5EEN A;  4IXV A;  1HQX A;  3C0Y A;  5G1C A;  5DC5 A;  5EFN A;  5IX0 A;  4Q3U A;  4A69 A;  4BZ8 A;  4ZUP A;  4RHQ A;  2VQM A;  1T69 A;  5IWG A;  3SJT A;  1P8Q A;  5EEI A;  5G1A A;  4MYN A;  1VKG A;  4G3H A;  3E6K A;  3NIO A;  5EFJ D;  1WVB A;  2VQQ A;  3TH7 A;  1P8N A;  3SFH A;  2CEV A;  3M1R A;  5D1B A;  4Q3V A;  5EF8 A;  5ICN B;  4QA6 A;  5HJA A;  3GN0 A;  4RN2 A;  3E9B A;  4FCK A;  1P8R A;  2EIV A;  2EF5 A;  5EFH A;  1ZPE A;  1WVA A;  2VQV A;  4Q3Q A;  1HQF A;  5THU A;  2VCG A;  3MMR A;  3E6V A;  2ZAV A;  4RN0 A;  4Q40 A;  1C3R A;  1D3V A;  2PHO A;  1ZZ1 A;  5G11 A;  4RHM A;  4ZUQ A;  1T67 A;  5D1D A;  3MJL A;  3F06 A;  3E8Z A;  3Q9B A;  5G0I A;  3EWF A;  4IXU A;  1HQH A;  1T4T A;  1C3S A;  3EW8 A;  4RLA A;  3CEV A;  4HWW A;  4LY1 A;  1TBJ A;  5G0H A;  3THH A;  1ZPG A;  4CQF A;  1WOG A;  4Q3P A;  4CBY A;  4DZ4 A;  4Q3T A;  4RHL A;  2AEB A;  1R1O A;  1T64 A;  3PZL A;  1ZZ0 A;  3NIQ A;  4BZ7 A;  4I06 A;  3C0Z A;  3SL0 A;  3DJ8 A;  4MXR A;  1P8P A;  4QA2 A;  5G1B A;  4ZUM A;  3EZT A;  5DC8 A;  2V5X A;  5DC7 A;  5G0Y A;  1T5F A;  3MAX A;  5EF7 A;  2EF4 A;  3SKK A;  2VQW G;  1T4R A;  1P8M A;  4RHK A;  3LP7 A;  5EEK A;  4QA4 A;  1P8S A;  4BZ5 A;  5LI3 A;  4LXZ A;  3MFV A;  4GWD A;  4IE2 A;  5D1C A;  1CEV A;  2VQO A;  4GSV A;  2RLA A;  5EFG A;  4HZE A;  4IE3 A;  4QA5 A;  3MZ7 A;  3TF3 A;  3E8Q A;  4MYK A;  1ZZ3 A;  3EZP A;  3F0R A;  3F80 A;  4QA3 A;  4GSM A;  5EFB D;  4RN1 A;  1T5G A;  4ZUN A;  4ZUR A;  3MZ3 A;  5G0X A;  5G3W A;  3Q9E A;  4MYF A;  4GSZ A;  5EEF A;  4CBT A;  2VQJ A;  3ZNS A;  3SFF A;  3RLA A;  4ITY A;  5CEV A;  2A0M A;  3Q9C A;  4IU4 A;  5HJ9 A;  3THE A;  4BZ9 A;  4CEV A;  1TBL A;  1TBH A;  3KV2 A;  3MZ6 A;  4Q42 A;  4BKX B;  4GWC A;  5DC6 A;  3SL1 A;  1WOI A;  1HQG A;  4MYL A;  5G12 A;  3THJ A;  1C3P A;  4Q41 A;  1GQ6 A;  1HQ5 A;  2V5W A;  4ZUO A;  4Q3R C;  3RQD A;  5JI5 A;  1T4P A;  4IU5 A;  3Q9F A;  1RLA A;  3LP4 A;  3F07 A;  3NIP A;  5THS A;  5EFK B;  5G13 A;  1PQ3 A;  3LHL A;  4RHI A;  1TA1 A;  4Q3S A;  5G0J A; 
#chains in the Genus database with same CATH homology
 1GQ7 A;  3MFW A;  5RLA A;  1WOH A;  4IE1 A;  1P8O A;  2PLL A;  4RHJ A;  1T4S A;  4IU1 A;  4IU0 A;  4FCI A;  4Q3R A;  3GMZ A;  2PHA A;  4HXQ A;  1XFK A;  4IXV A;  1HQX A;  4Q3U A;  4RHQ A;  3SJT A;  1P8Q A;  4MYN A;  4G3H A;  3E6K A;  3NIO A;  1WVB A;  3TH7 A;  1P8N A;  2CEV A;  3M1R A;  4Q3V A;  5HJA A;  3GN0 A;  3E9B A;  4FCK A;  1P8R A;  2EIV A;  2EF5 A;  1ZPE A;  1WVA A;  4Q3Q A;  1HQF A;  3MMR A;  3E6V A;  2ZAV A;  4Q40 A;  1D3V A;  2PHO A;  4RHM A;  3MJL A;  3E8Z A;  4IXU A;  1HQH A;  1T4T A;  4RLA A;  3CEV A;  4HWW A;  1TBJ A;  3THH A;  1ZPG A;  1WOG A;  4Q3P A;  4DZ4 A;  4Q3T A;  4RHL A;  2AEB A;  1R1O A;  3PZL A;  3NIQ A;  4I06 A;  3SL0 A;  3DJ8 A;  4MXR A;  1P8P A;  1T5F A;  2EF4 A;  3SKK A;  1T4R A;  1P8M A;  4RHK A;  3LP7 A;  1P8S A;  3MFV A;  4GWD A;  4IE2 A;  1CEV A;  4GSV A;  2RLA A;  4HZE A;  4IE3 A;  3TF3 A;  3E8Q A;  4MYK A;  3F80 A;  4GSM A;  1T5G A;  4MYF A;  4GSZ A;  3RLA A;  4ITY A;  5CEV A;  2A0M A;  4IU4 A;  5HJ9 A;  3THE A;  4CEV A;  1TBL A;  1TBH A;  3KV2 A;  4Q42 A;  4GWC A;  3SL1 A;  1WOI A;  1HQG A;  4MYL A;  3THJ A;  4Q41 A;  1GQ6 A;  1HQ5 A;  4Q3R C;  1T4P A;  4IU5 A;  1RLA A;  3LP4 A;  3NIP A;  1PQ3 A;  3LHL A;  4RHI A;  1TA1 A;  4Q3S A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...