3F80A

(s)-2-amino-6-nitrohexanoic acid binds to human arginase i through multiple nitro-metal coordination interactions in the binuclear manganese cluster. resolution 1.60 a.
Total Genus 114
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
313
structure length
313
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title (S)-2-Amino-6-nitrohexanoic Acid Binds to Human Arginase I through Multiple Nitro-Metal Coordination Interactions in the Binuclear Manganese Cluster.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 114
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3f80A00
2A0MA 1XFKA 4MYNA 3NIPA 1WVBA 4I06A 1T4PA 4RHQA 1P8RA 5HJAA 3THJA 1WOHA 4FCIA 3MMRA 3PZLA 1P8PA 2CEVA 4HZEA 1HQ5A 3DJ8A 2PHOA 4RHMA 1T4RA 2PLLA 5CEVA 3MFWA 3NIQA 4RHLA 3MFVA 1WOIA 1TBLA 4Q3RA 4RHKA 3RLAA 4GSVA 3E9BA 3THEA 2AEBA 4IU4A 3SL1A 2ZAVA 4IU5A 4Q3VA 3MJLA 2RLAA 1T5GA 4Q3UA 1P8QA 4DZ4A 3SJTA 4IXUA 4FCKA 1GQ6A 4IU0A 1P8OA 4IE1A 4Q41A 3SL0A 4MYLA 4IU1A 3SKKA 1HQFA 3THHA 3E6KA 3TH7A 4GWDA 1CEVA 1P8NA 4Q3RC 4IXVA 4Q42A 4RHIA 3E8ZA 3LHLA 4G3HA 1R1OA 1T5FA 1D3VA 1T4TA 4Q3TA 4ITYA 2EF5A 2PHAA 3GN0A 4HXQA 4GSMA 1RLAA 3TF3A 4Q40A 4Q3QA 2EIVA 1HQXA 3F80A 4HWWA 4IE3A 1P8SA 3GMZA 4RLAA 1TA1A 3E8QA 1PQ3A 1ZPGA 1T4SA 4MYFA 4CEVA 3LP4A 3E6VA 4Q3PA 5HJ9A 1WVAA 1P8MA 1HQGA 4IE2A 4GSZA 3NIOA 4RHJA 1WOGA 3CEVA 1TBHA 3M1RA 4GWCA 3KV2A 2EF4A 4MYKA 4MXRA 4Q3SA 3LP7A 1ZPEA 1TBJA 5RLAA 1HQHA 1GQ7A
chains in the Genus database with same CATH superfamily
2VQOA 2A0MA 1XFKA 4MYNA 3NIPA 5FUEA 5EEKA 1WVBA 5THUA 4ZURA 3Q9FA 4I06A 1T4PA 1W22A 4RHQA 1P8RA 3RQDA 5HJAA 3THJA 1WOHA 5EENA 3EZTA 4FCIA 4RN0A 4QA3A 5THSA 4CBTA 5THTA 3MMRA 3PZLA 5EFBD 1P8PA 2CEVA 3Q9EA 4HZEA 4ZUQA 1HQ5A 3DJ8A 2PHOA 5G0JA 4QA7A 4RHMA 2VQQA 4BKXB 5DC7A 1T4RA 2PLLA 4QA2A 3SFFA 3MZ3A 5CEVA 3MFWA 3NIQA 4RHLA 3MFVA 5EEMA 5JI5A 4BZ6A 1C3RA 1WOIA 5EFHA 3F0RA 1VKGA 3MENA 1TBLA 5G1BA 4Q3RA 4RHKA 5EF7A 4ZUPA 3RLAA 4GSVA 3E9BA 3MZ4A 3THEA 2AEBA 4IU4A 3SL1A 3EWFA 2ZAVA 4IU5A 4Q3VA 3MJLA 2RLAA 1T67A 1T5GA 1ZZ1A 2VQMA 1ZZ3A 1P8QA 4Q3UA 5EF8A 2VQWG 4DZ4A 3SJTA 4IXUA 4FCKA 4QA5A 1GQ6A 2VQVA 4IU0A 1P8OA 5BWZA 5G17A 1C3SA 4IE1A 4Q41A 5G0XA 3SFHA 3SL0A 3C0YA 2VQJA 4MYLA 3F07A 4IU1A 5G12A 2GH6A 5A2SA 3SKKA 1HQFA 3THHA 5G0HA 3E6KA 4QA1A 3EZPA 3TH7A 4LY1A 1ZZ0A 4GWDA 2V5WA 1CEVA 1P8NA 4CBYA 4Q3RC 5ICNB 4IXVA 4Q42A 4RHIA 5D1BA 5EFGA 5IWGA 3MAXA 3E8ZA 3LHLA 4G3HA 5EEIA 1R1OA 1T5FA 4RN1A 4ZUOA 4BZ7A 1D3VA 1T4TA 4Q3TA 3Q9CA 4ITYA 2EF5A 2PHAA 3GN0A 4HXQA 4GSMA 4ZUNA 5G13A 5G1CA 1RLAA 3TF3A 4Q40A 4Q3QA 5EFKB 5G0GA 2VCGA 2EIVA 1HQXA 3F80A 3ZNRA 5IX0A 5G0YA 4QA0A 3EW8A 4HWWA 5DC6A 4A69A 4IE3A 4BZ8A 5G1AA 4BZ5A 5EFNA 5G0IA 1C3PA 1P8SA 3GMZA 3Q9BA 4RLAA 1TA1A 3E8QA 3F06A 1PQ3A 1ZPGA 5EEFA 5THVA 1T4SA 5DC5A 4MYFA 4CEVA 1T69A 1T64A 3LP4A 4QA4A 5D1CA 5DC8A 4ZUMA 3E6VA 5G10A 3ZNSA 4Q3PA 5EFJD 5HJ9A 1WVAA 1P8MA 4QA6A 1HQGA 4IE2A 4RN2A 4GSZA 3NIOA 5G11A 4RHJA 4BZ9A 5G3WA 1WOGA 2V5XA 4LXZA 5FCWA 3CEVA 1TBHA 5D1DA 4CQFA 3M1RA 4GWCA 3MZ6A 3KV2A 2EF4A 4MYKA 4MXRA 5LI3A 3C0ZA 4Q3SA 3LP7A 1ZPEA 3MZ7A 1TBJA 3C10A 5RLAA 1HQHA 1GQ7A
chains in the Genus database with same CATH topology
2A0MA 1XFKA 4MYNA 3NIPA 1WVBA 4I06A 1T4PA 4RHQA 1P8RA 5HJAA 3THJA 1WOHA 4FCIA 3MMRA 3PZLA 1P8PA 2CEVA 4HZEA 1HQ5A 3DJ8A 2PHOA 4RHMA 1T4RA 2PLLA 5CEVA 3MFWA 3NIQA 4RHLA 3MFVA 1WOIA 1TBLA 4Q3RA 4RHKA 3RLAA 4GSVA 3E9BA 3THEA 2AEBA 4IU4A 3SL1A 2ZAVA 4IU5A 4Q3VA 3MJLA 2RLAA 1T5GA 4Q3UA 1P8QA 4DZ4A 3SJTA 4IXUA 4FCKA 1GQ6A 4IU0A 1P8OA 4IE1A 4Q41A 3SL0A 4MYLA 4IU1A 3SKKA 1HQFA 3THHA 3E6KA 3TH7A 4GWDA 1CEVA 1P8NA 4Q3RC 4IXVA 4Q42A 4RHIA 3E8ZA 3LHLA 4G3HA 1R1OA 1T5FA 1D3VA 1T4TA 4Q3TA 4ITYA 2EF5A 2PHAA 3GN0A 4HXQA 4GSMA 1RLAA 3TF3A 4Q40A 4Q3QA 2EIVA 1HQXA 3F80A 4HWWA 4IE3A 1P8SA 3GMZA 4RLAA 1TA1A 3E8QA 1PQ3A 1ZPGA 1T4SA 4MYFA 4CEVA 3LP4A 3E6VA 4Q3PA 5HJ9A 1WVAA 1P8MA 1HQGA 4IE2A 4GSZA 3NIOA 4RHJA 1WOGA 3CEVA 1TBHA 3M1RA 4GWCA 3KV2A 2EF4A 4MYKA 4MXRA 4Q3SA 3LP7A 1ZPEA 1TBJA 5RLAA 1HQHA 1GQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A0M A;  1XFK A;  4MYN A;  3NIP A;  1WVB A;  4I06 A;  1T4P A;  4RHQ A;  1P8R A;  5HJA A;  3THJ A;  1WOH A;  4FCI A;  3MMR A;  3PZL A;  1P8P A;  2CEV A;  4HZE A;  1HQ5 A;  3DJ8 A;  2PHO A;  4RHM A;  1T4R A;  2PLL A;  5CEV A;  3MFW A;  3NIQ A;  4RHL A;  3MFV A;  1WOI A;  1TBL A;  4Q3R A;  4RHK A;  3RLA A;  4GSV A;  3E9B A;  3THE A;  2AEB A;  4IU4 A;  3SL1 A;  2ZAV A;  4IU5 A;  4Q3V A;  3MJL A;  2RLA A;  1T5G A;  4Q3U A;  1P8Q A;  4DZ4 A;  3SJT A;  4IXU A;  4FCK A;  1GQ6 A;  4IU0 A;  1P8O A;  4IE1 A;  4Q41 A;  3SL0 A;  4MYL A;  4IU1 A;  3SKK A;  1HQF A;  3THH A;  3E6K A;  3TH7 A;  4GWD A;  1CEV A;  1P8N A;  4Q3R C;  4IXV A;  4Q42 A;  4RHI A;  3E8Z A;  3LHL A;  4G3H A;  1R1O A;  1T5F A;  1D3V A;  1T4T A;  4Q3T A;  4ITY A;  2EF5 A;  2PHA A;  3GN0 A;  4HXQ A;  4GSM A;  1RLA A;  3TF3 A;  4Q40 A;  4Q3Q A;  2EIV A;  1HQX A;  3F80 A;  4HWW A;  4IE3 A;  1P8S A;  3GMZ A;  4RLA A;  1TA1 A;  3E8Q A;  1PQ3 A;  1ZPG A;  1T4S A;  4MYF A;  4CEV A;  3LP4 A;  3E6V A;  4Q3P A;  5HJ9 A;  1WVA A;  1P8M A;  1HQG A;  4IE2 A;  4GSZ A;  3NIO A;  4RHJ A;  1WOG A;  3CEV A;  1TBH A;  3M1R A;  4GWC A;  3KV2 A;  2EF4 A;  4MYK A;  4MXR A;  4Q3S A;  3LP7 A;  1ZPE A;  1TBJ A;  5RLA A;  1HQH A;  1GQ7 A; 
#chains in the Genus database with same CATH topology
 2VQO A;  2A0M A;  1XFK A;  4MYN A;  3NIP A;  5FUE A;  5EEK A;  1WVB A;  5THU A;  4ZUR A;  3Q9F A;  4I06 A;  1T4P A;  1W22 A;  4RHQ A;  1P8R A;  3RQD A;  5HJA A;  3THJ A;  1WOH A;  5EEN A;  3EZT A;  4FCI A;  4RN0 A;  4QA3 A;  5THS A;  4CBT A;  5THT A;  3MMR A;  3PZL A;  5EFB D;  1P8P A;  2CEV A;  3Q9E A;  4HZE A;  4ZUQ A;  1HQ5 A;  3DJ8 A;  2PHO A;  5G0J A;  4QA7 A;  4RHM A;  2VQQ A;  4BKX B;  5DC7 A;  1T4R A;  2PLL A;  4QA2 A;  3SFF A;  3MZ3 A;  5CEV A;  3MFW A;  3NIQ A;  4RHL A;  3MFV A;  5EEM A;  5JI5 A;  4BZ6 A;  1C3R A;  1WOI A;  5EFH A;  3F0R A;  1VKG A;  3MEN A;  1TBL A;  5G1B A;  4Q3R A;  4RHK A;  5EF7 A;  4ZUP A;  3RLA A;  4GSV A;  3E9B A;  3MZ4 A;  3THE A;  2AEB A;  4IU4 A;  3SL1 A;  3EWF A;  2ZAV A;  4IU5 A;  4Q3V A;  3MJL A;  2RLA A;  1T67 A;  1T5G A;  1ZZ1 A;  2VQM A;  1ZZ3 A;  1P8Q A;  4Q3U A;  5EF8 A;  2VQW G;  4DZ4 A;  3SJT A;  4IXU A;  4FCK A;  4QA5 A;  1GQ6 A;  2VQV A;  4IU0 A;  1P8O A;  5BWZ A;  5G17 A;  1C3S A;  4IE1 A;  4Q41 A;  5G0X A;  3SFH A;  3SL0 A;  3C0Y A;  2VQJ A;  4MYL A;  3F07 A;  4IU1 A;  5G12 A;  2GH6 A;  5A2S A;  3SKK A;  1HQF A;  3THH A;  5G0H A;  3E6K A;  4QA1 A;  3EZP A;  3TH7 A;  4LY1 A;  1ZZ0 A;  4GWD A;  2V5W A;  1CEV A;  1P8N A;  4CBY A;  4Q3R C;  5ICN B;  4IXV A;  4Q42 A;  4RHI A;  5D1B A;  5EFG A;  5IWG A;  3MAX A;  3E8Z A;  3LHL A;  4G3H A;  5EEI A;  1R1O A;  1T5F A;  4RN1 A;  4ZUO A;  4BZ7 A;  1D3V A;  1T4T A;  4Q3T A;  3Q9C A;  4ITY A;  2EF5 A;  2PHA A;  3GN0 A;  4HXQ A;  4GSM A;  4ZUN A;  5G13 A;  5G1C A;  1RLA A;  3TF3 A;  4Q40 A;  4Q3Q A;  5EFK B;  5G0G A;  2VCG A;  2EIV A;  1HQX A;  3F80 A;  3ZNR A;  5IX0 A;  5G0Y A;  4QA0 A;  3EW8 A;  4HWW A;  5DC6 A;  4A69 A;  4IE3 A;  4BZ8 A;  5G1A A;  4BZ5 A;  5EFN A;  5G0I A;  1C3P A;  1P8S A;  3GMZ A;  3Q9B A;  4RLA A;  1TA1 A;  3E8Q A;  3F06 A;  1PQ3 A;  1ZPG A;  5EEF A;  5THV A;  1T4S A;  5DC5 A;  4MYF A;  4CEV A;  1T69 A;  1T64 A;  3LP4 A;  4QA4 A;  5D1C A;  5DC8 A;  4ZUM A;  3E6V A;  5G10 A;  3ZNS A;  4Q3P A;  5EFJ D;  5HJ9 A;  1WVA A;  1P8M A;  4QA6 A;  1HQG A;  4IE2 A;  4RN2 A;  4GSZ A;  3NIO A;  5G11 A;  4RHJ A;  4BZ9 A;  5G3W A;  1WOG A;  2V5X A;  4LXZ A;  5FCW A;  3CEV A;  1TBH A;  5D1D A;  4CQF A;  3M1R A;  4GWC A;  3MZ6 A;  3KV2 A;  2EF4 A;  4MYK A;  4MXR A;  5LI3 A;  3C0Z A;  4Q3S A;  3LP7 A;  1ZPE A;  3MZ7 A;  1TBJ A;  3C10 A;  5RLA A;  1HQH A;  1GQ7 A; 
#chains in the Genus database with same CATH homology
 2A0M A;  1XFK A;  4MYN A;  3NIP A;  1WVB A;  4I06 A;  1T4P A;  4RHQ A;  1P8R A;  5HJA A;  3THJ A;  1WOH A;  4FCI A;  3MMR A;  3PZL A;  1P8P A;  2CEV A;  4HZE A;  1HQ5 A;  3DJ8 A;  2PHO A;  4RHM A;  1T4R A;  2PLL A;  5CEV A;  3MFW A;  3NIQ A;  4RHL A;  3MFV A;  1WOI A;  1TBL A;  4Q3R A;  4RHK A;  3RLA A;  4GSV A;  3E9B A;  3THE A;  2AEB A;  4IU4 A;  3SL1 A;  2ZAV A;  4IU5 A;  4Q3V A;  3MJL A;  2RLA A;  1T5G A;  4Q3U A;  1P8Q A;  4DZ4 A;  3SJT A;  4IXU A;  4FCK A;  1GQ6 A;  4IU0 A;  1P8O A;  4IE1 A;  4Q41 A;  3SL0 A;  4MYL A;  4IU1 A;  3SKK A;  1HQF A;  3THH A;  3E6K A;  3TH7 A;  4GWD A;  1CEV A;  1P8N A;  4Q3R C;  4IXV A;  4Q42 A;  4RHI A;  3E8Z A;  3LHL A;  4G3H A;  1R1O A;  1T5F A;  1D3V A;  1T4T A;  4Q3T A;  4ITY A;  2EF5 A;  2PHA A;  3GN0 A;  4HXQ A;  4GSM A;  1RLA A;  3TF3 A;  4Q40 A;  4Q3Q A;  2EIV A;  1HQX A;  3F80 A;  4HWW A;  4IE3 A;  1P8S A;  3GMZ A;  4RLA A;  1TA1 A;  3E8Q A;  1PQ3 A;  1ZPG A;  1T4S A;  4MYF A;  4CEV A;  3LP4 A;  3E6V A;  4Q3P A;  5HJ9 A;  1WVA A;  1P8M A;  1HQG A;  4IE2 A;  4GSZ A;  3NIO A;  4RHJ A;  1WOG A;  3CEV A;  1TBH A;  3M1R A;  4GWC A;  3KV2 A;  2EF4 A;  4MYK A;  4MXR A;  4Q3S A;  3LP7 A;  1ZPE A;  1TBJ A;  5RLA A;  1HQH A;  1GQ7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...