3F80A

(s)-2-amino-6-nitrohexanoic acid binds to human arginase i through multiple nitro-metal coordination interactions in the binuclear manganese cluster. resolution 1.60 a.
Total Genus 114
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
313
structure length
313
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title (S)-2-Amino-6-nitrohexanoic Acid Binds to Human Arginase I through Multiple Nitro-Metal Coordination Interactions in the Binuclear Manganese Cluster.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 114
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3f80A00
1HQFA 1GQ6A 1TBLA 5CEVA 2A0MA 3F80A 1T5FA 4IE1A 4RHQA 4GWCA 4RHLA 4FCKA 1TBHA 4RHKA 1P8MA 3LP4A 1HQXA 3THHA 3RLAA 1TA1A 4MYKA 1WVAA 3E6VA 3E6KA 1T4RA 1P8QA 1GQ7A 2PHOA 4Q40A 4HZEA 3LP7A 1P8RA 4Q41A 4HXQA 1P8NA 1WOGA 4GSZA 4RHJA 1XFKA 4IE3A 1HQGA 2CEVA 4CEVA 3SL1A 3TH7A 1HQ5A 3LHLA 3SL0A 1D3VA 4RHMA 2EIVA 3NIQA 4GSVA 2PLLA 1P8OA 1T4TA 3E8ZA 2PHAA 3CEVA 1P8SA 3M1RA 4MYLA 3THEA 4MYNA 3MMRA 4GWDA 1ZPEA 3THJA 3NIOA 3NIPA 4Q3RC 4IU1A 5HJAA 3KV2A 3SKKA 1T4PA 4I06A 5RLAA 3GN0A 1T4SA 4MYFA 4Q3SA 4DZ4A 1WVBA 2EF4A 4IU4A 4RHIA 4Q42A 4Q3QA 4ITYA 4RLAA 3MJLA 4Q3RA 4Q3VA 3SJTA 3PZLA 3MFWA 4IU5A 2EF5A 1TBJA 2RLAA 3TF3A 1RLAA 5HJ9A 1ZPGA 1T5GA 4IXUA 1CEVA 4GSMA 4FCIA 4IE2A 3E8QA 4Q3PA 4IU0A 4G3HA 3GMZA 2ZAVA 4HWWA 4Q3TA 4IXVA 1R1OA 3E9BA 4MXRA 1HQHA 1P8PA 1WOIA 3DJ8A 1PQ3A 4Q3UA 3MFVA 2AEBA 1WOHA
chains in the Genus database with same CATH superfamily
1HQFA 1GQ6A 5EFHA 1TBLA 1T69A 5EFNA 5CEVA 2A0MA 3C0ZA 4CBYA 3F80A 1ZZ1A 3EZPA 4RN0A 4RN1A 4BZ8A 1ZZ0A 4RN2A 1T5FA 4IE1A 5G0XA 4RHQA 3RQDA 4GWCA 5G13A 3EZTA 5D1BA 4RHLA 5G0IA 4FCKA 1TBHA 5JI5A 5THVA 4RHKA 1P8MA 3LP4A 1HQXA 3EW8A 3Q9EA 1TA1A 4MYKA 1WVAA 3E6VA 3RLAA 3THHA 1C3RA 5G1AA 1T4RA 5G10A 3ZNSA 1P8QA 1GQ7A 2PHOA 4Q40A 4HZEA 3LP7A 1P8RA 4Q41A 3C0YA 4BZ9A 4HXQA 5G0HA 3MZ6A 1P8NA 3F0RA 2V5WA 1WOGA 4GSZA 4BZ5A 2V5XA 3MAXA 4RHJA 1XFKA 4IE3A 5IWGA 1HQGA 5G0JA 5DC8A 5EEIA 2CEVA 3MZ3A 4QA0A 4CEVA 5D1CA 3EWFA 3SL1A 4CQFA 3TH7A 3MZ4A 1HQ5A 5EF8A 4BKXB 1VKGA 3LHLA 5THSA 3SL0A 3Q9CA 1D3VA 4RHMA 2EIVA 4ZUOA 3NIQA 3MENA 4GSVA 2PLLA 5EENA 4BZ7A 5FCWA 1P8OA 1T4TA 2VQJA 5FUEA 3E8ZA 2PHAA 4QA7A 5EF7A 4ZUQA 3CEVA 1P8SA 3F07A 3M1RA 4CBTA 5DC6A 5THUA 5G1CA 4MYLA 3THEA 3Q9FA 5G0GA 4MYNA 5BWZA 3MMRA 4GWDA 5G1BA 1T67A 1ZPEA 3THJA 4LXZA 3NIOA 1T64A 2GH6A 3NIPA 5EFBD 4Q3RC 3ZNRA 4BZ6A 4IU1A 5HJAA 3KV2A 3SKKA 4A69A 5EEMA 1T4PA 4I06A 5RLAA 3GN0A 1T4SA 4MYFA 5LI3A 3SFHA 5D1DA 4Q3SA 5EEKA 4DZ4A 5EFGA 2VQMA 1WVBA 3F06A 4QA3A 2EF4A 2VQWG 4IU4A 4QA5A 1C3PA 4RHIA 5EFJD 4Q42A 4Q3QA 4ITYA 4RLAA 5G3WA 3MJLA 4Q3RA 4Q3VA 3Q9BA 5G17A 4ZUPA 5IX0A 1W22A 3SJTA 3PZLA 2VCGA 3MFWA 5G11A 4ZUMA 4IU5A 5G12A 5EFKB 2EF5A 1TBJA 2RLAA 3MFVA 4ZURA 1RLAA 5HJ9A 3TF3A 1ZZ3A 1ZPGA 1T5GA 4IXUA 5THTA 1CEVA 3SFFA 3MZ7A 4QA1A 4GSMA 4FCIA 4IE2A 2VQOA 3E8QA 4Q3PA 4IU0A 4G3HA 2VQVA 3GMZA 2ZAVA 4HWWA 5DC7A 5A2SA 4Q3TA 4IXVA 1R1OA 3E9BA 4QA2A 4ZUNA 2VQQA 4MXRA 5G0YA 1HQHA 1P8PA 4LY1A 3C10A 1WOIA 1C3SA 3DJ8A 5EEFA 1PQ3A 4QA6A 5ICNB 5DC5A 4Q3UA 3E6KA 4QA4A 2AEBA 1WOHA
chains in the Genus database with same CATH topology
1HQFA 1GQ6A 1TBLA 5CEVA 2A0MA 3F80A 1T5FA 4IE1A 4RHQA 4GWCA 4RHLA 4FCKA 1TBHA 4RHKA 1P8MA 3LP4A 1HQXA 3THHA 3RLAA 1TA1A 4MYKA 1WVAA 3E6VA 3E6KA 1T4RA 1P8QA 1GQ7A 2PHOA 4Q40A 4HZEA 3LP7A 1P8RA 4Q41A 4HXQA 1P8NA 1WOGA 4GSZA 4RHJA 1XFKA 4IE3A 1HQGA 2CEVA 4CEVA 3SL1A 3TH7A 1HQ5A 3LHLA 3SL0A 1D3VA 4RHMA 2EIVA 3NIQA 4GSVA 2PLLA 1P8OA 1T4TA 3E8ZA 2PHAA 3CEVA 1P8SA 3M1RA 4MYLA 3THEA 4MYNA 3MMRA 4GWDA 1ZPEA 3THJA 3NIOA 3NIPA 4Q3RC 4IU1A 5HJAA 3KV2A 3SKKA 1T4PA 4I06A 5RLAA 3GN0A 1T4SA 4MYFA 4Q3SA 4DZ4A 1WVBA 2EF4A 4IU4A 4RHIA 4Q42A 4Q3QA 4ITYA 4RLAA 3MJLA 4Q3RA 4Q3VA 3SJTA 3PZLA 3MFWA 4IU5A 2EF5A 1TBJA 2RLAA 3TF3A 1RLAA 5HJ9A 1ZPGA 1T5GA 4IXUA 1CEVA 4GSMA 4FCIA 4IE2A 3E8QA 4Q3PA 4IU0A 4G3HA 3GMZA 2ZAVA 4HWWA 4Q3TA 4IXVA 1R1OA 3E9BA 4MXRA 1HQHA 1P8PA 1WOIA 3DJ8A 1PQ3A 4Q3UA 3MFVA 2AEBA 1WOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HQF A;  1GQ6 A;  1TBL A;  5CEV A;  2A0M A;  3F80 A;  1T5F A;  4IE1 A;  4RHQ A;  4GWC A;  4RHL A;  4FCK A;  1TBH A;  4RHK A;  1P8M A;  3LP4 A;  1HQX A;  3THH A;  3RLA A;  1TA1 A;  4MYK A;  1WVA A;  3E6V A;  3E6K A;  1T4R A;  1P8Q A;  1GQ7 A;  2PHO A;  4Q40 A;  4HZE A;  3LP7 A;  1P8R A;  4Q41 A;  4HXQ A;  1P8N A;  1WOG A;  4GSZ A;  4RHJ A;  1XFK A;  4IE3 A;  1HQG A;  2CEV A;  4CEV A;  3SL1 A;  3TH7 A;  1HQ5 A;  3LHL A;  3SL0 A;  1D3V A;  4RHM A;  2EIV A;  3NIQ A;  4GSV A;  2PLL A;  1P8O A;  1T4T A;  3E8Z A;  2PHA A;  3CEV A;  1P8S A;  3M1R A;  4MYL A;  3THE A;  4MYN A;  3MMR A;  4GWD A;  1ZPE A;  3THJ A;  3NIO A;  3NIP A;  4Q3R C;  4IU1 A;  5HJA A;  3KV2 A;  3SKK A;  1T4P A;  4I06 A;  5RLA A;  3GN0 A;  1T4S A;  4MYF A;  4Q3S A;  4DZ4 A;  1WVB A;  2EF4 A;  4IU4 A;  4RHI A;  4Q42 A;  4Q3Q A;  4ITY A;  4RLA A;  3MJL A;  4Q3R A;  4Q3V A;  3SJT A;  3PZL A;  3MFW A;  4IU5 A;  2EF5 A;  1TBJ A;  2RLA A;  3TF3 A;  1RLA A;  5HJ9 A;  1ZPG A;  1T5G A;  4IXU A;  1CEV A;  4GSM A;  4FCI A;  4IE2 A;  3E8Q A;  4Q3P A;  4IU0 A;  4G3H A;  3GMZ A;  2ZAV A;  4HWW A;  4Q3T A;  4IXV A;  1R1O A;  3E9B A;  4MXR A;  1HQH A;  1P8P A;  1WOI A;  3DJ8 A;  1PQ3 A;  4Q3U A;  3MFV A;  2AEB A;  1WOH A; 
#chains in the Genus database with same CATH topology
 1HQF A;  1GQ6 A;  5EFH A;  1TBL A;  1T69 A;  5EFN A;  5CEV A;  2A0M A;  3C0Z A;  4CBY A;  3F80 A;  1ZZ1 A;  3EZP A;  4RN0 A;  4RN1 A;  4BZ8 A;  1ZZ0 A;  4RN2 A;  1T5F A;  4IE1 A;  5G0X A;  4RHQ A;  3RQD A;  4GWC A;  5G13 A;  3EZT A;  5D1B A;  4RHL A;  5G0I A;  4FCK A;  1TBH A;  5JI5 A;  5THV A;  4RHK A;  1P8M A;  3LP4 A;  1HQX A;  3EW8 A;  3Q9E A;  1TA1 A;  4MYK A;  1WVA A;  3E6V A;  3RLA A;  3THH A;  1C3R A;  5G1A A;  1T4R A;  5G10 A;  3ZNS A;  1P8Q A;  1GQ7 A;  2PHO A;  4Q40 A;  4HZE A;  3LP7 A;  1P8R A;  4Q41 A;  3C0Y A;  4BZ9 A;  4HXQ A;  5G0H A;  3MZ6 A;  1P8N A;  3F0R A;  2V5W A;  1WOG A;  4GSZ A;  4BZ5 A;  2V5X A;  3MAX A;  4RHJ A;  1XFK A;  4IE3 A;  5IWG A;  1HQG A;  5G0J A;  5DC8 A;  5EEI A;  2CEV A;  3MZ3 A;  4QA0 A;  4CEV A;  5D1C A;  3EWF A;  3SL1 A;  4CQF A;  3TH7 A;  3MZ4 A;  1HQ5 A;  5EF8 A;  4BKX B;  1VKG A;  3LHL A;  5THS A;  3SL0 A;  3Q9C A;  1D3V A;  4RHM A;  2EIV A;  4ZUO A;  3NIQ A;  3MEN A;  4GSV A;  2PLL A;  5EEN A;  4BZ7 A;  5FCW A;  1P8O A;  1T4T A;  2VQJ A;  5FUE A;  3E8Z A;  2PHA A;  4QA7 A;  5EF7 A;  4ZUQ A;  3CEV A;  1P8S A;  3F07 A;  3M1R A;  4CBT A;  5DC6 A;  5THU A;  5G1C A;  4MYL A;  3THE A;  3Q9F A;  5G0G A;  4MYN A;  5BWZ A;  3MMR A;  4GWD A;  5G1B A;  1T67 A;  1ZPE A;  3THJ A;  4LXZ A;  3NIO A;  1T64 A;  2GH6 A;  3NIP A;  5EFB D;  4Q3R C;  3ZNR A;  4BZ6 A;  4IU1 A;  5HJA A;  3KV2 A;  3SKK A;  4A69 A;  5EEM A;  1T4P A;  4I06 A;  5RLA A;  3GN0 A;  1T4S A;  4MYF A;  5LI3 A;  3SFH A;  5D1D A;  4Q3S A;  5EEK A;  4DZ4 A;  5EFG A;  2VQM A;  1WVB A;  3F06 A;  4QA3 A;  2EF4 A;  2VQW G;  4IU4 A;  4QA5 A;  1C3P A;  4RHI A;  5EFJ D;  4Q42 A;  4Q3Q A;  4ITY A;  4RLA A;  5G3W A;  3MJL A;  4Q3R A;  4Q3V A;  3Q9B A;  5G17 A;  4ZUP A;  5IX0 A;  1W22 A;  3SJT A;  3PZL A;  2VCG A;  3MFW A;  5G11 A;  4ZUM A;  4IU5 A;  5G12 A;  5EFK B;  2EF5 A;  1TBJ A;  2RLA A;  3MFV A;  4ZUR A;  1RLA A;  5HJ9 A;  3TF3 A;  1ZZ3 A;  1ZPG A;  1T5G A;  4IXU A;  5THT A;  1CEV A;  3SFF A;  3MZ7 A;  4QA1 A;  4GSM A;  4FCI A;  4IE2 A;  2VQO A;  3E8Q A;  4Q3P A;  4IU0 A;  4G3H A;  2VQV A;  3GMZ A;  2ZAV A;  4HWW A;  5DC7 A;  5A2S A;  4Q3T A;  4IXV A;  1R1O A;  3E9B A;  4QA2 A;  4ZUN A;  2VQQ A;  4MXR A;  5G0Y A;  1HQH A;  1P8P A;  4LY1 A;  3C10 A;  1WOI A;  1C3S A;  3DJ8 A;  5EEF A;  1PQ3 A;  4QA6 A;  5ICN B;  5DC5 A;  4Q3U A;  3E6K A;  4QA4 A;  2AEB A;  1WOH A; 
#chains in the Genus database with same CATH homology
 1HQF A;  1GQ6 A;  1TBL A;  5CEV A;  2A0M A;  3F80 A;  1T5F A;  4IE1 A;  4RHQ A;  4GWC A;  4RHL A;  4FCK A;  1TBH A;  4RHK A;  1P8M A;  3LP4 A;  1HQX A;  3THH A;  3RLA A;  1TA1 A;  4MYK A;  1WVA A;  3E6V A;  3E6K A;  1T4R A;  1P8Q A;  1GQ7 A;  2PHO A;  4Q40 A;  4HZE A;  3LP7 A;  1P8R A;  4Q41 A;  4HXQ A;  1P8N A;  1WOG A;  4GSZ A;  4RHJ A;  1XFK A;  4IE3 A;  1HQG A;  2CEV A;  4CEV A;  3SL1 A;  3TH7 A;  1HQ5 A;  3LHL A;  3SL0 A;  1D3V A;  4RHM A;  2EIV A;  3NIQ A;  4GSV A;  2PLL A;  1P8O A;  1T4T A;  3E8Z A;  2PHA A;  3CEV A;  1P8S A;  3M1R A;  4MYL A;  3THE A;  4MYN A;  3MMR A;  4GWD A;  1ZPE A;  3THJ A;  3NIO A;  3NIP A;  4Q3R C;  4IU1 A;  5HJA A;  3KV2 A;  3SKK A;  1T4P A;  4I06 A;  5RLA A;  3GN0 A;  1T4S A;  4MYF A;  4Q3S A;  4DZ4 A;  1WVB A;  2EF4 A;  4IU4 A;  4RHI A;  4Q42 A;  4Q3Q A;  4ITY A;  4RLA A;  3MJL A;  4Q3R A;  4Q3V A;  3SJT A;  3PZL A;  3MFW A;  4IU5 A;  2EF5 A;  1TBJ A;  2RLA A;  3TF3 A;  1RLA A;  5HJ9 A;  1ZPG A;  1T5G A;  4IXU A;  1CEV A;  4GSM A;  4FCI A;  4IE2 A;  3E8Q A;  4Q3P A;  4IU0 A;  4G3H A;  3GMZ A;  2ZAV A;  4HWW A;  4Q3T A;  4IXV A;  1R1O A;  3E9B A;  4MXR A;  1HQH A;  1P8P A;  1WOI A;  3DJ8 A;  1PQ3 A;  4Q3U A;  3MFV A;  2AEB A;  1WOH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...