3MMRA

Structure of plasmodium falciparum arginase in complex with abh
Total Genus 118
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
390
structure length
308
Chain Sequence
KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSENLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
pubmed doi rcsb
molecule tags Hydrolase
source organism Plasmodium falciparum 3d7
molecule keywords Arginase
total genus 118
structure length 308
sequence length 390
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2010-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3mmrA00
3RLAA 1WVBA 3KV2A 1GQ7A 4HXQA 2PHAA 4DZ4A 1T4TA 5HJ9A 4IE1A 1T5FA 3MMRA 4RHKA 4Q3RC 3PZLA 1P8NA 4ITYA 4Q3SA 3M1RA 4Q40A 1ZPEA 1TA1A 3E8ZA 1ZPGA 1HQXA 1P8MA 1XFKA 4Q3PA 4Q42A 4RHJA 4RHIA 2PLLA 4I06A 3NIPA 3NIQA 4MXRA 3CEVA 4G3HA 1P8SA 3THEA 5HJAA 1GQ6A 1T5GA 4IXVA 1R1OA 3SJTA 2EIVA 3LP7A 3DJ8A 4GWDA 1T4SA 1HQ5A 4IXUA 4MYFA 1RLAA 4IU1A 2CEVA 4GSMA 4RHQA 1P8PA 1WOHA 1P8QA 4HWWA 3THHA 3SKKA 1WVAA 2EF5A 4FCIA 3TF3A 3E8QA 3MFWA 3MFVA 3E6VA 4CEVA 5CEVA 2ZAVA 3E6KA 4FCKA 1D3VA 3LHLA 4IE2A 4RHLA 1HQHA 4IE3A 4Q3UA 1CEVA 3GMZA 4Q3TA 4GSVA 4GWCA 1T4PA 1P8OA 2RLAA 3TH7A 4IU0A 2PHOA 3GN0A 4Q3RA 3THJA 4MYNA 1HQFA 3F80A 1T4RA 4GSZA 1TBJA 1PQ3A 1HQGA 1TBHA 4IU5A 1P8RA 4Q41A 4IU4A 2AEBA 2EF4A 4MYLA 4MYKA 3LP4A 3E9BA 4RHMA 3SL0A 1WOGA 4Q3QA 4Q3VA 3SL1A 5RLAA 1WOIA 3NIOA 1TBLA 2A0MA 3MJLA 4RLAA 4HZEA
chains in the Genus database with same CATH superfamily
3RLAA 1WVBA 3MENA 4LY1A 3KV2A 1GQ7A 5G1BA 4HXQA 2PHAA 4DZ4A 1T4TA 1T69A 5HJ9A 5EFHA 2VQMA 4IE1A 1T5FA 3MMRA 4QA2A 5EFNA 4RHKA 4RN2A 4Q3RC 3EZPA 3PZLA 1P8NA 4ITYA 4Q3SA 3M1RA 3EW8A 1ZPEA 4Q40A 2VQOA 1ZZ1A 1TA1A 3EZTA 3E8ZA 1ZPGA 3MZ4A 1HQXA 5G17A 3C10A 2VQVA 1P8MA 5G0GA 1XFKA 4QA7A 3RQDA 3Q9CA 4Q3PA 5THUA 3Q9EA 1ZZ0A 4Q42A 4ZUPA 3SFHA 4RHJA 5LI3A 5THVA 4RHIA 5G0HA 2PLLA 4I06A 5G10A 3NIPA 3NIQA 4MXRA 5G0IA 5BWZA 3CEVA 4G3HA 5G0YA 2V5XA 1P8SA 5DC5A 3THEA 5HJAA 5A2SA 1GQ6A 1T5GA 4IXVA 4QA1A 1R1OA 5G13A 3C0ZA 3SJTA 2EIVA 3LP7A 4QA6A 1ZZ3A 3DJ8A 3F06A 4GWDA 5G3WA 2V5WA 1T4SA 5EFJD 1HQ5A 4IXUA 4MYFA 1RLAA 4BZ6A 4A69A 4IU1A 5G11A 4BZ5A 2CEVA 4GSMA 4RHQA 3SFFA 1P8PA 1WOHA 2VQQA 4ZUNA 5EFBD 1P8QA 4HWWA 3THHA 3SKKA 1WVAA 2EF5A 5DC8A 4FCIA 5DC6A 5EFGA 3TF3A 3E8QA 4CQFA 4QA5A 3MFWA 3E6VA 3MFVA 4CEVA 5CEVA 2ZAVA 5EEKA 5FCWA 3E6KA 4FCKA 1C3SA 1D3VA 4RN0A 3LHLA 4IE2A 4RHLA 1HQHA 4BZ7A 5G0JA 3MZ7A 4IE3A 2VQJA 3EWFA 4Q3UA 2VCGA 1CEVA 4ZURA 5FUEA 4QA3A 3GMZA 4BZ8A 4Q3TA 4GSVA 4GWCA 4BZ9A 1T4PA 1P8OA 2RLAA 3TH7A 4IU0A 5EEFA 2PHOA 3GN0A 4Q3RA 4QA0A 5EEMA 2VQWG 3THJA 3ZNRA 5D1DA 4MYNA 1VKGA 3MZ6A 4LXZA 5EF8A 4ZUQA 1HQFA 3F80A 1T4RA 4GSZA 5EFKB 3F0RA 1TBJA 5D1BA 5G0XA 4ZUOA 1T64A 1PQ3A 1HQGA 3MZ3A 5ICNB 1TBHA 4IU5A 5EENA 5G12A 3Q9FA 5EEIA 1P8RA 4Q41A 1T67A 5THSA 5G1AA 4IU4A 2AEBA 3ZNSA 2EF4A 4MYLA 4MYKA 4ZUMA 5JI5A 3LP4A 3E9BA 4RN1A 5G1CA 4RHMA 4BKXB 4QA4A 3MAXA 1C3PA 3C0YA 3SL0A 5EF7A 4CBTA 1W22A 1WOGA 4Q3QA 4Q3VA 5D1CA 5THTA 5IX0A 3SL1A 5IWGA 5RLAA 4CBYA 1C3RA 2GH6A 1WOIA 3F07A 3NIOA 1TBLA 2A0MA 5DC7A 3MJLA 3Q9BA 4RLAA 4HZEA
chains in the Genus database with same CATH topology
3RLAA 1WVBA 3KV2A 1GQ7A 4HXQA 2PHAA 4DZ4A 1T4TA 5HJ9A 4IE1A 1T5FA 3MMRA 4RHKA 4Q3RC 3PZLA 1P8NA 4ITYA 4Q3SA 3M1RA 4Q40A 1ZPEA 1TA1A 3E8ZA 1ZPGA 1HQXA 1P8MA 1XFKA 4Q3PA 4Q42A 4RHJA 4RHIA 2PLLA 4I06A 3NIPA 3NIQA 4MXRA 3CEVA 4G3HA 1P8SA 3THEA 5HJAA 1GQ6A 1T5GA 4IXVA 1R1OA 3SJTA 2EIVA 3LP7A 3DJ8A 4GWDA 1T4SA 1HQ5A 4IXUA 4MYFA 1RLAA 4IU1A 2CEVA 4GSMA 4RHQA 1P8PA 1WOHA 1P8QA 4HWWA 3THHA 3SKKA 1WVAA 2EF5A 4FCIA 3TF3A 3E8QA 3MFWA 3MFVA 3E6VA 4CEVA 5CEVA 2ZAVA 3E6KA 4FCKA 1D3VA 3LHLA 4IE2A 4RHLA 1HQHA 4IE3A 4Q3UA 1CEVA 3GMZA 4Q3TA 4GSVA 4GWCA 1T4PA 1P8OA 2RLAA 3TH7A 4IU0A 2PHOA 3GN0A 4Q3RA 3THJA 4MYNA 1HQFA 3F80A 1T4RA 4GSZA 1TBJA 1PQ3A 1HQGA 1TBHA 4IU5A 1P8RA 4Q41A 4IU4A 2AEBA 2EF4A 4MYLA 4MYKA 3LP4A 3E9BA 4RHMA 3SL0A 1WOGA 4Q3QA 4Q3VA 3SL1A 5RLAA 1WOIA 3NIOA 1TBLA 2A0MA 3MJLA 4RLAA 4HZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RLA A;  1WVB A;  3KV2 A;  1GQ7 A;  4HXQ A;  2PHA A;  4DZ4 A;  1T4T A;  5HJ9 A;  4IE1 A;  1T5F A;  3MMR A;  4RHK A;  4Q3R C;  3PZL A;  1P8N A;  4ITY A;  4Q3S A;  3M1R A;  4Q40 A;  1ZPE A;  1TA1 A;  3E8Z A;  1ZPG A;  1HQX A;  1P8M A;  1XFK A;  4Q3P A;  4Q42 A;  4RHJ A;  4RHI A;  2PLL A;  4I06 A;  3NIP A;  3NIQ A;  4MXR A;  3CEV A;  4G3H A;  1P8S A;  3THE A;  5HJA A;  1GQ6 A;  1T5G A;  4IXV A;  1R1O A;  3SJT A;  2EIV A;  3LP7 A;  3DJ8 A;  4GWD A;  1T4S A;  1HQ5 A;  4IXU A;  4MYF A;  1RLA A;  4IU1 A;  2CEV A;  4GSM A;  4RHQ A;  1P8P A;  1WOH A;  1P8Q A;  4HWW A;  3THH A;  3SKK A;  1WVA A;  2EF5 A;  4FCI A;  3TF3 A;  3E8Q A;  3MFW A;  3MFV A;  3E6V A;  4CEV A;  5CEV A;  2ZAV A;  3E6K A;  4FCK A;  1D3V A;  3LHL A;  4IE2 A;  4RHL A;  1HQH A;  4IE3 A;  4Q3U A;  1CEV A;  3GMZ A;  4Q3T A;  4GSV A;  4GWC A;  1T4P A;  1P8O A;  2RLA A;  3TH7 A;  4IU0 A;  2PHO A;  3GN0 A;  4Q3R A;  3THJ A;  4MYN A;  1HQF A;  3F80 A;  1T4R A;  4GSZ A;  1TBJ A;  1PQ3 A;  1HQG A;  1TBH A;  4IU5 A;  1P8R A;  4Q41 A;  4IU4 A;  2AEB A;  2EF4 A;  4MYL A;  4MYK A;  3LP4 A;  3E9B A;  4RHM A;  3SL0 A;  1WOG A;  4Q3Q A;  4Q3V A;  3SL1 A;  5RLA A;  1WOI A;  3NIO A;  1TBL A;  2A0M A;  3MJL A;  4RLA A;  4HZE A; 
#chains in the Genus database with same CATH topology
 3RLA A;  1WVB A;  3MEN A;  4LY1 A;  3KV2 A;  1GQ7 A;  5G1B A;  4HXQ A;  2PHA A;  4DZ4 A;  1T4T A;  1T69 A;  5HJ9 A;  5EFH A;  2VQM A;  4IE1 A;  1T5F A;  3MMR A;  4QA2 A;  5EFN A;  4RHK A;  4RN2 A;  4Q3R C;  3EZP A;  3PZL A;  1P8N A;  4ITY A;  4Q3S A;  3M1R A;  3EW8 A;  1ZPE A;  4Q40 A;  2VQO A;  1ZZ1 A;  1TA1 A;  3EZT A;  3E8Z A;  1ZPG A;  3MZ4 A;  1HQX A;  5G17 A;  3C10 A;  2VQV A;  1P8M A;  5G0G A;  1XFK A;  4QA7 A;  3RQD A;  3Q9C A;  4Q3P A;  5THU A;  3Q9E A;  1ZZ0 A;  4Q42 A;  4ZUP A;  3SFH A;  4RHJ A;  5LI3 A;  5THV A;  4RHI A;  5G0H A;  2PLL A;  4I06 A;  5G10 A;  3NIP A;  3NIQ A;  4MXR A;  5G0I A;  5BWZ A;  3CEV A;  4G3H A;  5G0Y A;  2V5X A;  1P8S A;  5DC5 A;  3THE A;  5HJA A;  5A2S A;  1GQ6 A;  1T5G A;  4IXV A;  4QA1 A;  1R1O A;  5G13 A;  3C0Z A;  3SJT A;  2EIV A;  3LP7 A;  4QA6 A;  1ZZ3 A;  3DJ8 A;  3F06 A;  4GWD A;  5G3W A;  2V5W A;  1T4S A;  5EFJ D;  1HQ5 A;  4IXU A;  4MYF A;  1RLA A;  4BZ6 A;  4A69 A;  4IU1 A;  5G11 A;  4BZ5 A;  2CEV A;  4GSM A;  4RHQ A;  3SFF A;  1P8P A;  1WOH A;  2VQQ A;  4ZUN A;  5EFB D;  1P8Q A;  4HWW A;  3THH A;  3SKK A;  1WVA A;  2EF5 A;  5DC8 A;  4FCI A;  5DC6 A;  5EFG A;  3TF3 A;  3E8Q A;  4CQF A;  4QA5 A;  3MFW A;  3E6V A;  3MFV A;  4CEV A;  5CEV A;  2ZAV A;  5EEK A;  5FCW A;  3E6K A;  4FCK A;  1C3S A;  1D3V A;  4RN0 A;  3LHL A;  4IE2 A;  4RHL A;  1HQH A;  4BZ7 A;  5G0J A;  3MZ7 A;  4IE3 A;  2VQJ A;  3EWF A;  4Q3U A;  2VCG A;  1CEV A;  4ZUR A;  5FUE A;  4QA3 A;  3GMZ A;  4BZ8 A;  4Q3T A;  4GSV A;  4GWC A;  4BZ9 A;  1T4P A;  1P8O A;  2RLA A;  3TH7 A;  4IU0 A;  5EEF A;  2PHO A;  3GN0 A;  4Q3R A;  4QA0 A;  5EEM A;  2VQW G;  3THJ A;  3ZNR A;  5D1D A;  4MYN A;  1VKG A;  3MZ6 A;  4LXZ A;  5EF8 A;  4ZUQ A;  1HQF A;  3F80 A;  1T4R A;  4GSZ A;  5EFK B;  3F0R A;  1TBJ A;  5D1B A;  5G0X A;  4ZUO A;  1T64 A;  1PQ3 A;  1HQG A;  3MZ3 A;  5ICN B;  1TBH A;  4IU5 A;  5EEN A;  5G12 A;  3Q9F A;  5EEI A;  1P8R A;  4Q41 A;  1T67 A;  5THS A;  5G1A A;  4IU4 A;  2AEB A;  3ZNS A;  2EF4 A;  4MYL A;  4MYK A;  4ZUM A;  5JI5 A;  3LP4 A;  3E9B A;  4RN1 A;  5G1C A;  4RHM A;  4BKX B;  4QA4 A;  3MAX A;  1C3P A;  3C0Y A;  3SL0 A;  5EF7 A;  4CBT A;  1W22 A;  1WOG A;  4Q3Q A;  4Q3V A;  5D1C A;  5THT A;  5IX0 A;  3SL1 A;  5IWG A;  5RLA A;  4CBY A;  1C3R A;  2GH6 A;  1WOI A;  3F07 A;  3NIO A;  1TBL A;  2A0M A;  5DC7 A;  3MJL A;  3Q9B A;  4RLA A;  4HZE A; 
#chains in the Genus database with same CATH homology
 3RLA A;  1WVB A;  3KV2 A;  1GQ7 A;  4HXQ A;  2PHA A;  4DZ4 A;  1T4T A;  5HJ9 A;  4IE1 A;  1T5F A;  3MMR A;  4RHK A;  4Q3R C;  3PZL A;  1P8N A;  4ITY A;  4Q3S A;  3M1R A;  4Q40 A;  1ZPE A;  1TA1 A;  3E8Z A;  1ZPG A;  1HQX A;  1P8M A;  1XFK A;  4Q3P A;  4Q42 A;  4RHJ A;  4RHI A;  2PLL A;  4I06 A;  3NIP A;  3NIQ A;  4MXR A;  3CEV A;  4G3H A;  1P8S A;  3THE A;  5HJA A;  1GQ6 A;  1T5G A;  4IXV A;  1R1O A;  3SJT A;  2EIV A;  3LP7 A;  3DJ8 A;  4GWD A;  1T4S A;  1HQ5 A;  4IXU A;  4MYF A;  1RLA A;  4IU1 A;  2CEV A;  4GSM A;  4RHQ A;  1P8P A;  1WOH A;  1P8Q A;  4HWW A;  3THH A;  3SKK A;  1WVA A;  2EF5 A;  4FCI A;  3TF3 A;  3E8Q A;  3MFW A;  3MFV A;  3E6V A;  4CEV A;  5CEV A;  2ZAV A;  3E6K A;  4FCK A;  1D3V A;  3LHL A;  4IE2 A;  4RHL A;  1HQH A;  4IE3 A;  4Q3U A;  1CEV A;  3GMZ A;  4Q3T A;  4GSV A;  4GWC A;  1T4P A;  1P8O A;  2RLA A;  3TH7 A;  4IU0 A;  2PHO A;  3GN0 A;  4Q3R A;  3THJ A;  4MYN A;  1HQF A;  3F80 A;  1T4R A;  4GSZ A;  1TBJ A;  1PQ3 A;  1HQG A;  1TBH A;  4IU5 A;  1P8R A;  4Q41 A;  4IU4 A;  2AEB A;  2EF4 A;  4MYL A;  4MYK A;  3LP4 A;  3E9B A;  4RHM A;  3SL0 A;  1WOG A;  4Q3Q A;  4Q3V A;  3SL1 A;  5RLA A;  1WOI A;  3NIO A;  1TBL A;  2A0M A;  3MJL A;  4RLA A;  4HZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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