3TH7A

Crystal structure of unliganded co2+2-hai (ph 7.0)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of complexes with cobalt-reconstituted human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 114
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2011-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3th7A00
1P8RA 3RLAA 3THEA 3MJLA 3SKKA 4GWCA 1T5FA 4MYLA 1PQ3A 4Q40A 4IXUA 4HWWA 1XFKA 4Q42A 4RHKA 2EIVA 1P8MA 3E9BA 1T4TA 4IU0A 4DZ4A 5HJ9A 5HJAA 1P8PA 4GSVA 4RHJA 3MFWA 2PLLA 3NIOA 3SL0A 2ZAVA 5RLAA 1GQ6A 3KV2A 1R1OA 2RLAA 3TH7A 3E8ZA 4IE3A 3SJTA 4G3HA 4GSZA 4RHLA 1TBJA 1P8QA 1ZPGA 4RHQA 4IU1A 3LHLA 4Q41A 3GMZA 1HQFA 3CEVA 4FCIA 1WVBA 4IU5A 1T4SA 3DJ8A 3E6VA 4RHMA 3E8QA 1TBHA 4ITYA 4FCKA 1P8NA 4GSMA 3TF3A 1P8OA 4Q3RA 1HQ5A 4MXRA 4Q3VA 2AEBA 4IXVA 5CEVA 1GQ7A 1CEVA 4Q3SA 1T4PA 1P8SA 4IE1A 3NIPA 1T4RA 4MYNA 4IU4A 3LP4A 4Q3TA 2PHOA 1TBLA 3THJA 1ZPEA 1HQHA 4Q3QA 3LP7A 4CEVA 4MYFA 4Q3PA 4GWDA 1T5GA 2CEVA 3F80A 1D3VA 4HXQA 1WOGA 4Q3UA 1WVAA 4I06A 3GN0A 1HQXA 1WOIA 4HZEA 4MYKA 4RLAA 2EF4A 4IE2A 1HQGA 1TA1A 3M1RA 3MFVA 3PZLA 1RLAA 3NIQA 2PHAA 3MMRA 4Q3RC 3SL1A 2EF5A 2A0MA 3THHA 3E6KA 4RHIA 1WOHA
chains in the Genus database with same CATH superfamily
1P8RA 4QA1A 5G3WA 3RLAA 3THEA 3Q9CA 3MJLA 5G0HA 4RN0A 3SKKA 4GWCA 1T5FA 4MYLA 1PQ3A 4Q40A 4IXUA 4RN2A 4HWWA 1XFKA 5IWGA 3EWFA 3MZ4A 4ZUQA 4Q42A 4RHKA 4QA4A 2EIVA 2VCGA 1P8MA 3E9BA 1T4TA 3F07A 3EZTA 4IU0A 4ZUMA 5G17A 5HJ9A 4DZ4A 2GH6A 5HJAA 1P8PA 5G1AA 2VQQA 4GSVA 4RHJA 3MFWA 4ZUOA 5DC7A 4A69A 2PLLA 3NIOA 3SL0A 4LXZA 2ZAVA 5RLAA 1GQ6A 3KV2A 5D1DA 1R1OA 2RLAA 4RN1A 5EFKB 5EFJD 4ZUNA 3E8ZA 5G11A 4IE3A 3MZ3A 3SJTA 3TH7A 5EEFA 4G3HA 4CBYA 1T67A 4GSZA 4RHLA 1TBJA 4CQFA 1P8QA 1ZPGA 5BWZA 5G12A 5IX0A 4RHQA 5EFNA 4IU1A 3C0ZA 3LHLA 4QA5A 4QA3A 3GMZA 4Q41A 1HQFA 3CEVA 4FCIA 1WVBA 2V5XA 5LI3A 5G0XA 4IU5A 1T4SA 3DJ8A 3EZPA 4CBTA 4BZ9A 3E6VA 5D1BA 4RHMA 5THUA 3E8QA 1TBHA 4LY1A 5EEMA 5FCWA 4BZ8A 2V5WA 2VQOA 4ITYA 4FCKA 1P8NA 4QA0A 4QA6A 2VQVA 4GSMA 3SFHA 3RQDA 1T69A 1P8OA 5G1CA 1C3PA 5ICNB 4Q3RA 3TF3A 1HQ5A 3SFFA 4QA2A 1C3SA 3F0RA 4MXRA 4Q3VA 2AEBA 4IXVA 5EFGA 5G0IA 5CEVA 5EEKA 1GQ7A 3EW8A 1CEVA 4Q3SA 4QA7A 3MZ6A 1T4PA 3Q9FA 1P8SA 4IE1A 3NIPA 1T4RA 4MYNA 4ZURA 1VKGA 4IU4A 3LP4A 5DC8A 5DC6A 4Q3TA 5G0YA 2PHOA 1TBLA 4BZ5A 3C10A 3C0YA 5JI5A 5G1BA 2VQWG 3THJA 1ZPEA 1HQHA 3F06A 4Q3QA 5G10A 4ZUPA 3LP7A 5EFBD 4CEVA 4MYFA 3MENA 4GWDA 4Q3PA 5EFHA 5THSA 4BZ6A 1T64A 1T5GA 1ZZ0A 2CEVA 2VQMA 3F80A 3MZ7A 5EENA 1D3VA 4HXQA 3Q9EA 5EF8A 1WOGA 1C3RA 4Q3UA 3ZNRA 1WVAA 5D1CA 4I06A 3GN0A 1HQXA 1WOIA 5DC5A 4HZEA 4BZ7A 4MYKA 4RLAA 5EEIA 5G13A 4BKXB 5A2SA 2VQJA 2EF4A 3Q9BA 4IE2A 5THTA 1ZZ3A 1HQGA 1TA1A 1W22A 3M1RA 3MFVA 3PZLA 1RLAA 3NIQA 2PHAA 3MMRA 4Q3RC 5THVA 3SL1A 2EF5A 5EF7A 5G0GA 2A0MA 3THHA 3ZNSA 3MAXA 5FUEA 1ZZ1A 5G0JA 3E6KA 4RHIA 1WOHA
chains in the Genus database with same CATH topology
1P8RA 3RLAA 3THEA 3MJLA 3SKKA 4GWCA 1T5FA 4MYLA 1PQ3A 4Q40A 4IXUA 4HWWA 1XFKA 4Q42A 4RHKA 2EIVA 1P8MA 3E9BA 1T4TA 4IU0A 4DZ4A 5HJ9A 5HJAA 1P8PA 4GSVA 4RHJA 3MFWA 2PLLA 3NIOA 3SL0A 2ZAVA 5RLAA 1GQ6A 3KV2A 1R1OA 2RLAA 3TH7A 3E8ZA 4IE3A 3SJTA 4G3HA 4GSZA 4RHLA 1TBJA 1P8QA 1ZPGA 4RHQA 4IU1A 3LHLA 4Q41A 3GMZA 1HQFA 3CEVA 4FCIA 1WVBA 4IU5A 1T4SA 3DJ8A 3E6VA 4RHMA 3E8QA 1TBHA 4ITYA 4FCKA 1P8NA 4GSMA 3TF3A 1P8OA 4Q3RA 1HQ5A 4MXRA 4Q3VA 2AEBA 4IXVA 5CEVA 1GQ7A 1CEVA 4Q3SA 1T4PA 1P8SA 4IE1A 3NIPA 1T4RA 4MYNA 4IU4A 3LP4A 4Q3TA 2PHOA 1TBLA 3THJA 1ZPEA 1HQHA 4Q3QA 3LP7A 4CEVA 4MYFA 4Q3PA 4GWDA 1T5GA 2CEVA 3F80A 1D3VA 4HXQA 1WOGA 4Q3UA 1WVAA 4I06A 3GN0A 1HQXA 1WOIA 4HZEA 4MYKA 4RLAA 2EF4A 4IE2A 1HQGA 1TA1A 3M1RA 3MFVA 3PZLA 1RLAA 3NIQA 2PHAA 3MMRA 4Q3RC 3SL1A 2EF5A 2A0MA 3THHA 3E6KA 4RHIA 1WOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8R A;  3RLA A;  3THE A;  3MJL A;  3SKK A;  4GWC A;  1T5F A;  4MYL A;  1PQ3 A;  4Q40 A;  4IXU A;  4HWW A;  1XFK A;  4Q42 A;  4RHK A;  2EIV A;  1P8M A;  3E9B A;  1T4T A;  4IU0 A;  4DZ4 A;  5HJ9 A;  5HJA A;  1P8P A;  4GSV A;  4RHJ A;  3MFW A;  2PLL A;  3NIO A;  3SL0 A;  2ZAV A;  5RLA A;  1GQ6 A;  3KV2 A;  1R1O A;  2RLA A;  3TH7 A;  3E8Z A;  4IE3 A;  3SJT A;  4G3H A;  4GSZ A;  4RHL A;  1TBJ A;  1P8Q A;  1ZPG A;  4RHQ A;  4IU1 A;  3LHL A;  4Q41 A;  3GMZ A;  1HQF A;  3CEV A;  4FCI A;  1WVB A;  4IU5 A;  1T4S A;  3DJ8 A;  3E6V A;  4RHM A;  3E8Q A;  1TBH A;  4ITY A;  4FCK A;  1P8N A;  4GSM A;  3TF3 A;  1P8O A;  4Q3R A;  1HQ5 A;  4MXR A;  4Q3V A;  2AEB A;  4IXV A;  5CEV A;  1GQ7 A;  1CEV A;  4Q3S A;  1T4P A;  1P8S A;  4IE1 A;  3NIP A;  1T4R A;  4MYN A;  4IU4 A;  3LP4 A;  4Q3T A;  2PHO A;  1TBL A;  3THJ A;  1ZPE A;  1HQH A;  4Q3Q A;  3LP7 A;  4CEV A;  4MYF A;  4Q3P A;  4GWD A;  1T5G A;  2CEV A;  3F80 A;  1D3V A;  4HXQ A;  1WOG A;  4Q3U A;  1WVA A;  4I06 A;  3GN0 A;  1HQX A;  1WOI A;  4HZE A;  4MYK A;  4RLA A;  2EF4 A;  4IE2 A;  1HQG A;  1TA1 A;  3M1R A;  3MFV A;  3PZL A;  1RLA A;  3NIQ A;  2PHA A;  3MMR A;  4Q3R C;  3SL1 A;  2EF5 A;  2A0M A;  3THH A;  3E6K A;  4RHI A;  1WOH A; 
#chains in the Genus database with same CATH topology
 1P8R A;  4QA1 A;  5G3W A;  3RLA A;  3THE A;  3Q9C A;  3MJL A;  5G0H A;  4RN0 A;  3SKK A;  4GWC A;  1T5F A;  4MYL A;  1PQ3 A;  4Q40 A;  4IXU A;  4RN2 A;  4HWW A;  1XFK A;  5IWG A;  3EWF A;  3MZ4 A;  4ZUQ A;  4Q42 A;  4RHK A;  4QA4 A;  2EIV A;  2VCG A;  1P8M A;  3E9B A;  1T4T A;  3F07 A;  3EZT A;  4IU0 A;  4ZUM A;  5G17 A;  5HJ9 A;  4DZ4 A;  2GH6 A;  5HJA A;  1P8P A;  5G1A A;  2VQQ A;  4GSV A;  4RHJ A;  3MFW A;  4ZUO A;  5DC7 A;  4A69 A;  2PLL A;  3NIO A;  3SL0 A;  4LXZ A;  2ZAV A;  5RLA A;  1GQ6 A;  3KV2 A;  5D1D A;  1R1O A;  2RLA A;  4RN1 A;  5EFK B;  5EFJ D;  4ZUN A;  3E8Z A;  5G11 A;  4IE3 A;  3MZ3 A;  3SJT A;  3TH7 A;  5EEF A;  4G3H A;  4CBY A;  1T67 A;  4GSZ A;  4RHL A;  1TBJ A;  4CQF A;  1P8Q A;  1ZPG A;  5BWZ A;  5G12 A;  5IX0 A;  4RHQ A;  5EFN A;  4IU1 A;  3C0Z A;  3LHL A;  4QA5 A;  4QA3 A;  3GMZ A;  4Q41 A;  1HQF A;  3CEV A;  4FCI A;  1WVB A;  2V5X A;  5LI3 A;  5G0X A;  4IU5 A;  1T4S A;  3DJ8 A;  3EZP A;  4CBT A;  4BZ9 A;  3E6V A;  5D1B A;  4RHM A;  5THU A;  3E8Q A;  1TBH A;  4LY1 A;  5EEM A;  5FCW A;  4BZ8 A;  2V5W A;  2VQO A;  4ITY A;  4FCK A;  1P8N A;  4QA0 A;  4QA6 A;  2VQV A;  4GSM A;  3SFH A;  3RQD A;  1T69 A;  1P8O A;  5G1C A;  1C3P A;  5ICN B;  4Q3R A;  3TF3 A;  1HQ5 A;  3SFF A;  4QA2 A;  1C3S A;  3F0R A;  4MXR A;  4Q3V A;  2AEB A;  4IXV A;  5EFG A;  5G0I A;  5CEV A;  5EEK A;  1GQ7 A;  3EW8 A;  1CEV A;  4Q3S A;  4QA7 A;  3MZ6 A;  1T4P A;  3Q9F A;  1P8S A;  4IE1 A;  3NIP A;  1T4R A;  4MYN A;  4ZUR A;  1VKG A;  4IU4 A;  3LP4 A;  5DC8 A;  5DC6 A;  4Q3T A;  5G0Y A;  2PHO A;  1TBL A;  4BZ5 A;  3C10 A;  3C0Y A;  5JI5 A;  5G1B A;  2VQW G;  3THJ A;  1ZPE A;  1HQH A;  3F06 A;  4Q3Q A;  5G10 A;  4ZUP A;  3LP7 A;  5EFB D;  4CEV A;  4MYF A;  3MEN A;  4GWD A;  4Q3P A;  5EFH A;  5THS A;  4BZ6 A;  1T64 A;  1T5G A;  1ZZ0 A;  2CEV A;  2VQM A;  3F80 A;  3MZ7 A;  5EEN A;  1D3V A;  4HXQ A;  3Q9E A;  5EF8 A;  1WOG A;  1C3R A;  4Q3U A;  3ZNR A;  1WVA A;  5D1C A;  4I06 A;  3GN0 A;  1HQX A;  1WOI A;  5DC5 A;  4HZE A;  4BZ7 A;  4MYK A;  4RLA A;  5EEI A;  5G13 A;  4BKX B;  5A2S A;  2VQJ A;  2EF4 A;  3Q9B A;  4IE2 A;  5THT A;  1ZZ3 A;  1HQG A;  1TA1 A;  1W22 A;  3M1R A;  3MFV A;  3PZL A;  1RLA A;  3NIQ A;  2PHA A;  3MMR A;  4Q3R C;  5THV A;  3SL1 A;  2EF5 A;  5EF7 A;  5G0G A;  2A0M A;  3THH A;  3ZNS A;  3MAX A;  5FUE A;  1ZZ1 A;  5G0J A;  3E6K A;  4RHI A;  1WOH A; 
#chains in the Genus database with same CATH homology
 1P8R A;  3RLA A;  3THE A;  3MJL A;  3SKK A;  4GWC A;  1T5F A;  4MYL A;  1PQ3 A;  4Q40 A;  4IXU A;  4HWW A;  1XFK A;  4Q42 A;  4RHK A;  2EIV A;  1P8M A;  3E9B A;  1T4T A;  4IU0 A;  4DZ4 A;  5HJ9 A;  5HJA A;  1P8P A;  4GSV A;  4RHJ A;  3MFW A;  2PLL A;  3NIO A;  3SL0 A;  2ZAV A;  5RLA A;  1GQ6 A;  3KV2 A;  1R1O A;  2RLA A;  3TH7 A;  3E8Z A;  4IE3 A;  3SJT A;  4G3H A;  4GSZ A;  4RHL A;  1TBJ A;  1P8Q A;  1ZPG A;  4RHQ A;  4IU1 A;  3LHL A;  4Q41 A;  3GMZ A;  1HQF A;  3CEV A;  4FCI A;  1WVB A;  4IU5 A;  1T4S A;  3DJ8 A;  3E6V A;  4RHM A;  3E8Q A;  1TBH A;  4ITY A;  4FCK A;  1P8N A;  4GSM A;  3TF3 A;  1P8O A;  4Q3R A;  1HQ5 A;  4MXR A;  4Q3V A;  2AEB A;  4IXV A;  5CEV A;  1GQ7 A;  1CEV A;  4Q3S A;  1T4P A;  1P8S A;  4IE1 A;  3NIP A;  1T4R A;  4MYN A;  4IU4 A;  3LP4 A;  4Q3T A;  2PHO A;  1TBL A;  3THJ A;  1ZPE A;  1HQH A;  4Q3Q A;  3LP7 A;  4CEV A;  4MYF A;  4Q3P A;  4GWD A;  1T5G A;  2CEV A;  3F80 A;  1D3V A;  4HXQ A;  1WOG A;  4Q3U A;  1WVA A;  4I06 A;  3GN0 A;  1HQX A;  1WOI A;  4HZE A;  4MYK A;  4RLA A;  2EF4 A;  4IE2 A;  1HQG A;  1TA1 A;  3M1R A;  3MFV A;  3PZL A;  1RLA A;  3NIQ A;  2PHA A;  3MMR A;  4Q3R C;  3SL1 A;  2EF5 A;  2A0M A;  3THH A;  3E6K A;  4RHI A;  1WOH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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