3CEVA

Arginase from bacillus caldevelox, complexed with l-arginine
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
298
structure length
298
Chain Sequence
KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 117
structure length 298
sequence length 298
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3cevA00
4GWDA 4Q41A 4RHJA 3SJTA 1WOHA 3DJ8A 4G3HA 3SL0A 2CEVA 3LHLA 4IU5A 3E9BA 1P8OA 3E6VA 1TBHA 4GSZA 4RLAA 3F80A 3GN0A 1WOGA 1GQ7A 4MYKA 3TH7A 1WVBA 4HXQA 4RHKA 3NIOA 4Q40A 1WOIA 1T5FA 1T4RA 3MJLA 4RHMA 3KV2A 1HQFA 3SKKA 1P8NA 4Q3TA 1T4PA 2EF4A 4IU0A 3LP4A 4I06A 3CEVA 5HJ9A 1CEVA 1WVAA 3THEA 1P8MA 1PQ3A 1T4SA 1P8QA 1TBJA 4MXRA 4Q3QA 4RHQA 3M1RA 3THHA 4Q42A 4HZEA 4FCIA 4GSMA 1HQGA 2PLLA 2A0MA 2EF5A 3PZLA 1D3VA 1TBLA 4RHLA 1P8RA 2ZAVA 3THJA 1T5GA 3E8ZA 4IE2A 4IE3A 4GWCA 4MYFA 1P8SA 1P8PA 4IU4A 4GSVA 2EIVA 4IXVA 1HQHA 3MMRA 3E8QA 1RLAA 4FCKA 3LP7A 1HQ5A 4IE1A 1ZPGA 3RLAA 2PHAA 4DZ4A 3TF3A 2RLAA 4Q3PA 3MFWA 1GQ6A 4MYNA 1XFKA 3SL1A 1HQXA 1R1OA 4ITYA 3GMZA 3E6KA 5HJAA 1TA1A 1T4TA 4IXUA 1ZPEA 4HWWA 3NIQA 4MYLA 5CEVA 2AEBA 4IU1A 4Q3RA 2PHOA 5RLAA 4CEVA 4Q3SA 4Q3UA 4Q3RC 4RHIA 3MFVA 3NIPA 4Q3VA
chains in the Genus database with same CATH superfamily
3EWFA 4GWDA 4Q41A 4RHJA 4ZUOA 4QA6A 3SJTA 1WOHA 3DJ8A 4G3HA 2VQWG 2GH6A 5D1CA 3SL0A 5THTA 5FCWA 3Q9CA 2CEVA 3LHLA 4IU5A 4QA0A 4BZ9A 3E9BA 5G12A 1P8OA 3E6VA 1TBHA 4GSZA 4RLAA 3F80A 5EFGA 2V5XA 3GN0A 1WOGA 1GQ7A 4MYKA 3F06A 5FUEA 5G0YA 5EEIA 3TH7A 1VKGA 5EFBD 1WVBA 1ZZ1A 4HXQA 4RHKA 3NIOA 4Q40A 5G1CA 1WOIA 1T5FA 1T4RA 3MAXA 5EF8A 3MJLA 4RHMA 5EFNA 5EFJD 5IWGA 3SFHA 4ZUQA 3KV2A 1HQFA 3SKKA 3Q9BA 1P8NA 2VQOA 1T4PA 4Q3TA 2EF4A 4RN1A 4IU0A 3LP4A 4QA3A 5DC6A 5A2SA 4I06A 3CEVA 5EENA 5HJ9A 1C3PA 5DC7A 1CEVA 1C3RA 1WVAA 3C10A 4RN0A 4ZUNA 3EW8A 3MENA 3ZNSA 3THEA 4A69A 1P8MA 1PQ3A 1T4SA 1P8QA 1TBJA 4MXRA 4Q3QA 4RHQA 4BZ5A 3M1RA 3THHA 4Q42A 4CQFA 4HZEA 4RN2A 4FCIA 4LY1A 5JI5A 5DC5A 4GSMA 3SFFA 3F0RA 2V5WA 1HQGA 5G0GA 5THVA 2PLLA 2A0MA 5G11A 2EF5A 3PZLA 3Q9EA 1D3VA 1TBLA 4BZ7A 5THSA 4RHLA 1ZZ3A 1P8RA 5D1DA 2ZAVA 3THJA 3MZ7A 4QA2A 1T5GA 4ZUPA 5EFKB 3E8ZA 4IE2A 4IE3A 3MZ4A 4GWCA 4MYFA 5DC8A 4ZUMA 1P8SA 1P8PA 4IU4A 4GSVA 2EIVA 3EZTA 1W22A 5EF7A 4BKXB 3C0ZA 4IXVA 3C0YA 1HQHA 3MZ6A 3MMRA 2VQMA 3E8QA 5THUA 5IX0A 2VCGA 5EFHA 1RLAA 4FCKA 3LP7A 3RQDA 4CBYA 1HQ5A 4IE1A 5EEMA 5LI3A 1ZPGA 3RLAA 5G10A 2PHAA 4DZ4A 3TF3A 5G17A 5EEKA 2RLAA 2VQVA 4Q3PA 1GQ6A 3MFWA 4MYNA 1XFKA 5G0IA 4QA1A 5G0JA 3SL1A 1HQXA 5BWZA 5ICNB 1R1OA 4ITYA 1T64A 3GMZA 3E6KA 4LXZA 4ZURA 4QA5A 1T67A 1ZZ0A 5G0XA 5G0HA 3ZNRA 5HJAA 1TA1A 1T4TA 5G1AA 5G1BA 4IXUA 1ZPEA 3Q9FA 3F07A 4HWWA 1T69A 3EZPA 3NIQA 4BZ6A 4QA4A 4MYLA 5CEVA 4CBTA 2AEBA 5G13A 4IU1A 4Q3RA 5EEFA 2PHOA 5RLAA 4QA7A 4CEVA 5G3WA 4Q3SA 1C3SA 4Q3UA 5D1BA 4Q3RC 2VQQA 3MFVA 4RHIA 3MZ3A 3NIPA 4Q3VA 2VQJA 4BZ8A
chains in the Genus database with same CATH topology
4GWDA 4Q41A 4RHJA 3SJTA 1WOHA 3DJ8A 4G3HA 3SL0A 2CEVA 3LHLA 4IU5A 3E9BA 1P8OA 3E6VA 1TBHA 4GSZA 4RLAA 3F80A 3GN0A 1WOGA 1GQ7A 4MYKA 3TH7A 1WVBA 4HXQA 4RHKA 3NIOA 4Q40A 1WOIA 1T5FA 1T4RA 3MJLA 4RHMA 3KV2A 1HQFA 3SKKA 1P8NA 4Q3TA 1T4PA 2EF4A 4IU0A 3LP4A 4I06A 3CEVA 5HJ9A 1CEVA 1WVAA 3THEA 1P8MA 1PQ3A 1T4SA 1P8QA 1TBJA 4MXRA 4Q3QA 4RHQA 3M1RA 3THHA 4Q42A 4HZEA 4FCIA 4GSMA 1HQGA 2PLLA 2A0MA 2EF5A 3PZLA 1D3VA 1TBLA 4RHLA 1P8RA 2ZAVA 3THJA 1T5GA 3E8ZA 4IE2A 4IE3A 4GWCA 4MYFA 1P8SA 1P8PA 4IU4A 4GSVA 2EIVA 4IXVA 1HQHA 3MMRA 3E8QA 1RLAA 4FCKA 3LP7A 1HQ5A 4IE1A 1ZPGA 3RLAA 2PHAA 4DZ4A 3TF3A 2RLAA 4Q3PA 3MFWA 1GQ6A 4MYNA 1XFKA 3SL1A 1HQXA 1R1OA 4ITYA 3GMZA 3E6KA 5HJAA 1TA1A 1T4TA 4IXUA 1ZPEA 4HWWA 3NIQA 4MYLA 5CEVA 2AEBA 4IU1A 4Q3RA 2PHOA 5RLAA 4CEVA 4Q3SA 4Q3UA 4Q3RC 4RHIA 3MFVA 3NIPA 4Q3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GWD A;  4Q41 A;  4RHJ A;  3SJT A;  1WOH A;  3DJ8 A;  4G3H A;  3SL0 A;  2CEV A;  3LHL A;  4IU5 A;  3E9B A;  1P8O A;  3E6V A;  1TBH A;  4GSZ A;  4RLA A;  3F80 A;  3GN0 A;  1WOG A;  1GQ7 A;  4MYK A;  3TH7 A;  1WVB A;  4HXQ A;  4RHK A;  3NIO A;  4Q40 A;  1WOI A;  1T5F A;  1T4R A;  3MJL A;  4RHM A;  3KV2 A;  1HQF A;  3SKK A;  1P8N A;  4Q3T A;  1T4P A;  2EF4 A;  4IU0 A;  3LP4 A;  4I06 A;  3CEV A;  5HJ9 A;  1CEV A;  1WVA A;  3THE A;  1P8M A;  1PQ3 A;  1T4S A;  1P8Q A;  1TBJ A;  4MXR A;  4Q3Q A;  4RHQ A;  3M1R A;  3THH A;  4Q42 A;  4HZE A;  4FCI A;  4GSM A;  1HQG A;  2PLL A;  2A0M A;  2EF5 A;  3PZL A;  1D3V A;  1TBL A;  4RHL A;  1P8R A;  2ZAV A;  3THJ A;  1T5G A;  3E8Z A;  4IE2 A;  4IE3 A;  4GWC A;  4MYF A;  1P8S A;  1P8P A;  4IU4 A;  4GSV A;  2EIV A;  4IXV A;  1HQH A;  3MMR A;  3E8Q A;  1RLA A;  4FCK A;  3LP7 A;  1HQ5 A;  4IE1 A;  1ZPG A;  3RLA A;  2PHA A;  4DZ4 A;  3TF3 A;  2RLA A;  4Q3P A;  3MFW A;  1GQ6 A;  4MYN A;  1XFK A;  3SL1 A;  1HQX A;  1R1O A;  4ITY A;  3GMZ A;  3E6K A;  5HJA A;  1TA1 A;  1T4T A;  4IXU A;  1ZPE A;  4HWW A;  3NIQ A;  4MYL A;  5CEV A;  2AEB A;  4IU1 A;  4Q3R A;  2PHO A;  5RLA A;  4CEV A;  4Q3S A;  4Q3U A;  4Q3R C;  4RHI A;  3MFV A;  3NIP A;  4Q3V A; 
#chains in the Genus database with same CATH topology
 3EWF A;  4GWD A;  4Q41 A;  4RHJ A;  4ZUO A;  4QA6 A;  3SJT A;  1WOH A;  3DJ8 A;  4G3H A;  2VQW G;  2GH6 A;  5D1C A;  3SL0 A;  5THT A;  5FCW A;  3Q9C A;  2CEV A;  3LHL A;  4IU5 A;  4QA0 A;  4BZ9 A;  3E9B A;  5G12 A;  1P8O A;  3E6V A;  1TBH A;  4GSZ A;  4RLA A;  3F80 A;  5EFG A;  2V5X A;  3GN0 A;  1WOG A;  1GQ7 A;  4MYK A;  3F06 A;  5FUE A;  5G0Y A;  5EEI A;  3TH7 A;  1VKG A;  5EFB D;  1WVB A;  1ZZ1 A;  4HXQ A;  4RHK A;  3NIO A;  4Q40 A;  5G1C A;  1WOI A;  1T5F A;  1T4R A;  3MAX A;  5EF8 A;  3MJL A;  4RHM A;  5EFN A;  5EFJ D;  5IWG A;  3SFH A;  4ZUQ A;  3KV2 A;  1HQF A;  3SKK A;  3Q9B A;  1P8N A;  2VQO A;  1T4P A;  4Q3T A;  2EF4 A;  4RN1 A;  4IU0 A;  3LP4 A;  4QA3 A;  5DC6 A;  5A2S A;  4I06 A;  3CEV A;  5EEN A;  5HJ9 A;  1C3P A;  5DC7 A;  1CEV A;  1C3R A;  1WVA A;  3C10 A;  4RN0 A;  4ZUN A;  3EW8 A;  3MEN A;  3ZNS A;  3THE A;  4A69 A;  1P8M A;  1PQ3 A;  1T4S A;  1P8Q A;  1TBJ A;  4MXR A;  4Q3Q A;  4RHQ A;  4BZ5 A;  3M1R A;  3THH A;  4Q42 A;  4CQF A;  4HZE A;  4RN2 A;  4FCI A;  4LY1 A;  5JI5 A;  5DC5 A;  4GSM A;  3SFF A;  3F0R A;  2V5W A;  1HQG A;  5G0G A;  5THV A;  2PLL A;  2A0M A;  5G11 A;  2EF5 A;  3PZL A;  3Q9E A;  1D3V A;  1TBL A;  4BZ7 A;  5THS A;  4RHL A;  1ZZ3 A;  1P8R A;  5D1D A;  2ZAV A;  3THJ A;  3MZ7 A;  4QA2 A;  1T5G A;  4ZUP A;  5EFK B;  3E8Z A;  4IE2 A;  4IE3 A;  3MZ4 A;  4GWC A;  4MYF A;  5DC8 A;  4ZUM A;  1P8S A;  1P8P A;  4IU4 A;  4GSV A;  2EIV A;  3EZT A;  1W22 A;  5EF7 A;  4BKX B;  3C0Z A;  4IXV A;  3C0Y A;  1HQH A;  3MZ6 A;  3MMR A;  2VQM A;  3E8Q A;  5THU A;  5IX0 A;  2VCG A;  5EFH A;  1RLA A;  4FCK A;  3LP7 A;  3RQD A;  4CBY A;  1HQ5 A;  4IE1 A;  5EEM A;  5LI3 A;  1ZPG A;  3RLA A;  5G10 A;  2PHA A;  4DZ4 A;  3TF3 A;  5G17 A;  5EEK A;  2RLA A;  2VQV A;  4Q3P A;  1GQ6 A;  3MFW A;  4MYN A;  1XFK A;  5G0I A;  4QA1 A;  5G0J A;  3SL1 A;  1HQX A;  5BWZ A;  5ICN B;  1R1O A;  4ITY A;  1T64 A;  3GMZ A;  3E6K A;  4LXZ A;  4ZUR A;  4QA5 A;  1T67 A;  1ZZ0 A;  5G0X A;  5G0H A;  3ZNR A;  5HJA A;  1TA1 A;  1T4T A;  5G1A A;  5G1B A;  4IXU A;  1ZPE A;  3Q9F A;  3F07 A;  4HWW A;  1T69 A;  3EZP A;  3NIQ A;  4BZ6 A;  4QA4 A;  4MYL A;  5CEV A;  4CBT A;  2AEB A;  5G13 A;  4IU1 A;  4Q3R A;  5EEF A;  2PHO A;  5RLA A;  4QA7 A;  4CEV A;  5G3W A;  4Q3S A;  1C3S A;  4Q3U A;  5D1B A;  4Q3R C;  2VQQ A;  3MFV A;  4RHI A;  3MZ3 A;  3NIP A;  4Q3V A;  2VQJ A;  4BZ8 A; 
#chains in the Genus database with same CATH homology
 4GWD A;  4Q41 A;  4RHJ A;  3SJT A;  1WOH A;  3DJ8 A;  4G3H A;  3SL0 A;  2CEV A;  3LHL A;  4IU5 A;  3E9B A;  1P8O A;  3E6V A;  1TBH A;  4GSZ A;  4RLA A;  3F80 A;  3GN0 A;  1WOG A;  1GQ7 A;  4MYK A;  3TH7 A;  1WVB A;  4HXQ A;  4RHK A;  3NIO A;  4Q40 A;  1WOI A;  1T5F A;  1T4R A;  3MJL A;  4RHM A;  3KV2 A;  1HQF A;  3SKK A;  1P8N A;  4Q3T A;  1T4P A;  2EF4 A;  4IU0 A;  3LP4 A;  4I06 A;  3CEV A;  5HJ9 A;  1CEV A;  1WVA A;  3THE A;  1P8M A;  1PQ3 A;  1T4S A;  1P8Q A;  1TBJ A;  4MXR A;  4Q3Q A;  4RHQ A;  3M1R A;  3THH A;  4Q42 A;  4HZE A;  4FCI A;  4GSM A;  1HQG A;  2PLL A;  2A0M A;  2EF5 A;  3PZL A;  1D3V A;  1TBL A;  4RHL A;  1P8R A;  2ZAV A;  3THJ A;  1T5G A;  3E8Z A;  4IE2 A;  4IE3 A;  4GWC A;  4MYF A;  1P8S A;  1P8P A;  4IU4 A;  4GSV A;  2EIV A;  4IXV A;  1HQH A;  3MMR A;  3E8Q A;  1RLA A;  4FCK A;  3LP7 A;  1HQ5 A;  4IE1 A;  1ZPG A;  3RLA A;  2PHA A;  4DZ4 A;  3TF3 A;  2RLA A;  4Q3P A;  3MFW A;  1GQ6 A;  4MYN A;  1XFK A;  3SL1 A;  1HQX A;  1R1O A;  4ITY A;  3GMZ A;  3E6K A;  5HJA A;  1TA1 A;  1T4T A;  4IXU A;  1ZPE A;  4HWW A;  3NIQ A;  4MYL A;  5CEV A;  2AEB A;  4IU1 A;  4Q3R A;  2PHO A;  5RLA A;  4CEV A;  4Q3S A;  4Q3U A;  4Q3R C;  4RHI A;  3MFV A;  3NIP A;  4Q3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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