3DJ8A

Synthesis of (2s)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase i
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
313
structure length
313
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 113
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3dj8A00
3LP7A 3NIOA 4GSVA 4GWCA 1ZPGA 3GN0A 4Q3VA 1HQHA 1PQ3A 1T4SA 1P8SA 3TH7A 5HJAA 2PHOA 3F80A 4I06A 4RHMA 2ZAVA 4IXVA 4Q3PA 4IE2A 1HQGA 1XFKA 3SL1A 4MYNA 3THHA 1T4PA 1WOHA 4DZ4A 4MYFA 5HJ9A 4FCIA 1T5FA 2PLLA 1WOGA 4Q40A 3CEVA 3NIQA 3E8ZA 3E6VA 2PHAA 3E8QA 3E6KA 4GSMA 4Q3RA 4HXQA 1P8MA 3SKKA 4RHJA 1WOIA 3TF3A 4GWDA 4RHLA 3KV2A 4IXUA 4Q3SA 1TBJA 3SL0A 1P8NA 1TA1A 1WVBA 1TBHA 3E9BA 1HQFA 4Q41A 1HQ5A 3MFVA 5RLAA 1TBLA 4IE3A 4RHKA 3LP4A 1T4RA 1GQ7A 3RLAA 3LHLA 4Q3RC 4Q3TA 1P8OA 2EF5A 2RLAA 1CEVA 4RHIA 3NIPA 2EF4A 3DJ8A 4IU5A 3THEA 4RLAA 1GQ6A 2AEBA 4IU4A 4HZEA 4MYKA 1T4TA 4Q42A 4Q3UA 4Q3QA 4IU0A 1T5GA 3MJLA 3MFWA 3MMRA 3THJA 4GSZA 5CEVA 3M1RA 4CEVA 1D3VA 3PZLA 1HQXA 4ITYA 4MXRA 4IE1A 3GMZA 1P8PA 2EIVA 4FCKA 2CEVA 4HWWA 4IU1A 1P8QA 1R1OA 3SJTA 1ZPEA 4G3HA 4RHQA 1WVAA 2A0MA 4MYLA 1RLAA 1P8RA
chains in the Genus database with same CATH superfamily
3LP7A 3NIOA 4GSVA 4GWCA 1ZPGA 3F06A 5EFJD 3MZ6A 3GN0A 3MAXA 5G0JA 4Q3VA 1HQHA 5G1CA 5EEKA 1ZZ1A 1PQ3A 1T4SA 1P8SA 4RN2A 5IWGA 3TH7A 5DC5A 2PHOA 4ZUOA 5G0HA 4BKXB 3F80A 5HJAA 4I06A 4RHMA 2ZAVA 5EFHA 4QA6A 4IXVA 4Q3PA 4IE2A 4QA2A 1HQGA 5A2SA 1XFKA 3SL1A 4MYNA 4BZ7A 3THHA 1T4PA 1WOHA 4DZ4A 2VQQA 4MYFA 2GH6A 5G0GA 5HJ9A 4A69A 4QA5A 4FCIA 1T5FA 4QA7A 3F0RA 2PLLA 1WOGA 5G3WA 5THTA 2VQVA 4ZUQA 2VQJA 4Q40A 4RN1A 3CEVA 3NIQA 3E8ZA 3E6VA 2PHAA 3MENA 5EEIA 5EFBD 3E8QA 3E6KA 4GSMA 5DC8A 4Q3RA 4HXQA 1P8MA 3SKKA 4RHJA 1WOIA 4ZURA 3F07A 3TF3A 4GWDA 4RHLA 5EEFA 5THVA 3KV2A 4IXUA 4Q3SA 1TBJA 3SL0A 5EEMA 5G11A 3C10A 1P8NA 3SFFA 1TA1A 1WVBA 3Q9FA 4LXZA 1TBHA 1T69A 2VQWG 3EZPA 3E9BA 5D1CA 1HQFA 3EWFA 4ZUMA 5G1AA 5D1DA 3MZ4A 3RQDA 1HQ5A 3MFVA 4Q41A 5G10A 5RLAA 3MZ7A 1TBLA 1VKGA 4IE3A 5DC6A 4QA0A 4RHKA 3LP4A 1T4RA 5EF8A 4CBTA 1GQ7A 4QA4A 1C3PA 5G1BA 4BZ8A 5LI3A 3ZNSA 3RLAA 3LHLA 2V5WA 4Q3RC 4Q3TA 1P8OA 2VQOA 3Q9EA 5G12A 2EF5A 5EFKB 2RLAA 1CEVA 4RHIA 5G13A 4CBYA 1C3RA 3NIPA 5D1BA 2EF4A 3DJ8A 4IU5A 5EENA 3THEA 4RLAA 1GQ6A 1ZZ3A 1T67A 4QA3A 2AEBA 5G0IA 3ZNRA 4IU4A 4HZEA 4LY1A 4MYKA 1T4TA 5THSA 5FCWA 4Q42A 3Q9BA 1T64A 4Q3UA 5G17A 4RN0A 3Q9CA 5G0YA 5ICNB 4Q3QA 2V5XA 4IU0A 5JI5A 1T5GA 3MJLA 3MFWA 4ZUNA 3C0YA 2VQMA 3MMRA 5EF7A 4BZ5A 3MZ3A 3THJA 4GSZA 5EFNA 4QA1A 3M1RA 5FUEA 5CEVA 3EW8A 4CEVA 5THUA 1D3VA 3PZLA 5DC7A 4BZ9A 5G0XA 4BZ6A 3C0ZA 3EZTA 1HQXA 4ITYA 4MXRA 1W22A 4IE1A 3GMZA 1P8PA 2EIVA 4FCKA 5EFGA 2CEVA 2VCGA 4HWWA 4ZUPA 4IU1A 1C3SA 1P8QA 1R1OA 1ZZ0A 1ZPEA 3SFHA 4G3HA 3SJTA 4RHQA 1WVAA 5IX0A 4CQFA 5BWZA 2A0MA 4MYLA 1RLAA 1P8RA
chains in the Genus database with same CATH topology
3LP7A 3NIOA 4GSVA 4GWCA 1ZPGA 3GN0A 4Q3VA 1HQHA 1PQ3A 1T4SA 1P8SA 3TH7A 5HJAA 2PHOA 3F80A 4I06A 4RHMA 2ZAVA 4IXVA 4Q3PA 4IE2A 1HQGA 1XFKA 3SL1A 4MYNA 3THHA 1T4PA 1WOHA 4DZ4A 4MYFA 5HJ9A 4FCIA 1T5FA 2PLLA 1WOGA 4Q40A 3CEVA 3NIQA 3E8ZA 3E6VA 2PHAA 3E8QA 3E6KA 4GSMA 4Q3RA 4HXQA 1P8MA 3SKKA 4RHJA 1WOIA 3TF3A 4GWDA 4RHLA 3KV2A 4IXUA 4Q3SA 1TBJA 3SL0A 1P8NA 1TA1A 1WVBA 1TBHA 3E9BA 1HQFA 4Q41A 1HQ5A 3MFVA 5RLAA 1TBLA 4IE3A 4RHKA 3LP4A 1T4RA 1GQ7A 3RLAA 3LHLA 4Q3RC 4Q3TA 1P8OA 2EF5A 2RLAA 1CEVA 4RHIA 3NIPA 2EF4A 3DJ8A 4IU5A 3THEA 4RLAA 1GQ6A 2AEBA 4IU4A 4HZEA 4MYKA 1T4TA 4Q42A 4Q3UA 4Q3QA 4IU0A 1T5GA 3MJLA 3MFWA 3MMRA 3THJA 4GSZA 5CEVA 3M1RA 4CEVA 1D3VA 3PZLA 1HQXA 4ITYA 4MXRA 4IE1A 3GMZA 1P8PA 2EIVA 4FCKA 2CEVA 4HWWA 4IU1A 1P8QA 1R1OA 3SJTA 1ZPEA 4G3HA 4RHQA 1WVAA 2A0MA 4MYLA 1RLAA 1P8RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LP7 A;  3NIO A;  4GSV A;  4GWC A;  1ZPG A;  3GN0 A;  4Q3V A;  1HQH A;  1PQ3 A;  1T4S A;  1P8S A;  3TH7 A;  5HJA A;  2PHO A;  3F80 A;  4I06 A;  4RHM A;  2ZAV A;  4IXV A;  4Q3P A;  4IE2 A;  1HQG A;  1XFK A;  3SL1 A;  4MYN A;  3THH A;  1T4P A;  1WOH A;  4DZ4 A;  4MYF A;  5HJ9 A;  4FCI A;  1T5F A;  2PLL A;  1WOG A;  4Q40 A;  3CEV A;  3NIQ A;  3E8Z A;  3E6V A;  2PHA A;  3E8Q A;  3E6K A;  4GSM A;  4Q3R A;  4HXQ A;  1P8M A;  3SKK A;  4RHJ A;  1WOI A;  3TF3 A;  4GWD A;  4RHL A;  3KV2 A;  4IXU A;  4Q3S A;  1TBJ A;  3SL0 A;  1P8N A;  1TA1 A;  1WVB A;  1TBH A;  3E9B A;  1HQF A;  4Q41 A;  1HQ5 A;  3MFV A;  5RLA A;  1TBL A;  4IE3 A;  4RHK A;  3LP4 A;  1T4R A;  1GQ7 A;  3RLA A;  3LHL A;  4Q3R C;  4Q3T A;  1P8O A;  2EF5 A;  2RLA A;  1CEV A;  4RHI A;  3NIP A;  2EF4 A;  3DJ8 A;  4IU5 A;  3THE A;  4RLA A;  1GQ6 A;  2AEB A;  4IU4 A;  4HZE A;  4MYK A;  1T4T A;  4Q42 A;  4Q3U A;  4Q3Q A;  4IU0 A;  1T5G A;  3MJL A;  3MFW A;  3MMR A;  3THJ A;  4GSZ A;  5CEV A;  3M1R A;  4CEV A;  1D3V A;  3PZL A;  1HQX A;  4ITY A;  4MXR A;  4IE1 A;  3GMZ A;  1P8P A;  2EIV A;  4FCK A;  2CEV A;  4HWW A;  4IU1 A;  1P8Q A;  1R1O A;  3SJT A;  1ZPE A;  4G3H A;  4RHQ A;  1WVA A;  2A0M A;  4MYL A;  1RLA A;  1P8R A; 
#chains in the Genus database with same CATH topology
 3LP7 A;  3NIO A;  4GSV A;  4GWC A;  1ZPG A;  3F06 A;  5EFJ D;  3MZ6 A;  3GN0 A;  3MAX A;  5G0J A;  4Q3V A;  1HQH A;  5G1C A;  5EEK A;  1ZZ1 A;  1PQ3 A;  1T4S A;  1P8S A;  4RN2 A;  5IWG A;  3TH7 A;  5DC5 A;  2PHO A;  4ZUO A;  5G0H A;  4BKX B;  3F80 A;  5HJA A;  4I06 A;  4RHM A;  2ZAV A;  5EFH A;  4QA6 A;  4IXV A;  4Q3P A;  4IE2 A;  4QA2 A;  1HQG A;  5A2S A;  1XFK A;  3SL1 A;  4MYN A;  4BZ7 A;  3THH A;  1T4P A;  1WOH A;  4DZ4 A;  2VQQ A;  4MYF A;  2GH6 A;  5G0G A;  5HJ9 A;  4A69 A;  4QA5 A;  4FCI A;  1T5F A;  4QA7 A;  3F0R A;  2PLL A;  1WOG A;  5G3W A;  5THT A;  2VQV A;  4ZUQ A;  2VQJ A;  4Q40 A;  4RN1 A;  3CEV A;  3NIQ A;  3E8Z A;  3E6V A;  2PHA A;  3MEN A;  5EEI A;  5EFB D;  3E8Q A;  3E6K A;  4GSM A;  5DC8 A;  4Q3R A;  4HXQ A;  1P8M A;  3SKK A;  4RHJ A;  1WOI A;  4ZUR A;  3F07 A;  3TF3 A;  4GWD A;  4RHL A;  5EEF A;  5THV A;  3KV2 A;  4IXU A;  4Q3S A;  1TBJ A;  3SL0 A;  5EEM A;  5G11 A;  3C10 A;  1P8N A;  3SFF A;  1TA1 A;  1WVB A;  3Q9F A;  4LXZ A;  1TBH A;  1T69 A;  2VQW G;  3EZP A;  3E9B A;  5D1C A;  1HQF A;  3EWF A;  4ZUM A;  5G1A A;  5D1D A;  3MZ4 A;  3RQD A;  1HQ5 A;  3MFV A;  4Q41 A;  5G10 A;  5RLA A;  3MZ7 A;  1TBL A;  1VKG A;  4IE3 A;  5DC6 A;  4QA0 A;  4RHK A;  3LP4 A;  1T4R A;  5EF8 A;  4CBT A;  1GQ7 A;  4QA4 A;  1C3P A;  5G1B A;  4BZ8 A;  5LI3 A;  3ZNS A;  3RLA A;  3LHL A;  2V5W A;  4Q3R C;  4Q3T A;  1P8O A;  2VQO A;  3Q9E A;  5G12 A;  2EF5 A;  5EFK B;  2RLA A;  1CEV A;  4RHI A;  5G13 A;  4CBY A;  1C3R A;  3NIP A;  5D1B A;  2EF4 A;  3DJ8 A;  4IU5 A;  5EEN A;  3THE A;  4RLA A;  1GQ6 A;  1ZZ3 A;  1T67 A;  4QA3 A;  2AEB A;  5G0I A;  3ZNR A;  4IU4 A;  4HZE A;  4LY1 A;  4MYK A;  1T4T A;  5THS A;  5FCW A;  4Q42 A;  3Q9B A;  1T64 A;  4Q3U A;  5G17 A;  4RN0 A;  3Q9C A;  5G0Y A;  5ICN B;  4Q3Q A;  2V5X A;  4IU0 A;  5JI5 A;  1T5G A;  3MJL A;  3MFW A;  4ZUN A;  3C0Y A;  2VQM A;  3MMR A;  5EF7 A;  4BZ5 A;  3MZ3 A;  3THJ A;  4GSZ A;  5EFN A;  4QA1 A;  3M1R A;  5FUE A;  5CEV A;  3EW8 A;  4CEV A;  5THU A;  1D3V A;  3PZL A;  5DC7 A;  4BZ9 A;  5G0X A;  4BZ6 A;  3C0Z A;  3EZT A;  1HQX A;  4ITY A;  4MXR A;  1W22 A;  4IE1 A;  3GMZ A;  1P8P A;  2EIV A;  4FCK A;  5EFG A;  2CEV A;  2VCG A;  4HWW A;  4ZUP A;  4IU1 A;  1C3S A;  1P8Q A;  1R1O A;  1ZZ0 A;  1ZPE A;  3SFH A;  4G3H A;  3SJT A;  4RHQ A;  1WVA A;  5IX0 A;  4CQF A;  5BWZ A;  2A0M A;  4MYL A;  1RLA A;  1P8R A; 
#chains in the Genus database with same CATH homology
 3LP7 A;  3NIO A;  4GSV A;  4GWC A;  1ZPG A;  3GN0 A;  4Q3V A;  1HQH A;  1PQ3 A;  1T4S A;  1P8S A;  3TH7 A;  5HJA A;  2PHO A;  3F80 A;  4I06 A;  4RHM A;  2ZAV A;  4IXV A;  4Q3P A;  4IE2 A;  1HQG A;  1XFK A;  3SL1 A;  4MYN A;  3THH A;  1T4P A;  1WOH A;  4DZ4 A;  4MYF A;  5HJ9 A;  4FCI A;  1T5F A;  2PLL A;  1WOG A;  4Q40 A;  3CEV A;  3NIQ A;  3E8Z A;  3E6V A;  2PHA A;  3E8Q A;  3E6K A;  4GSM A;  4Q3R A;  4HXQ A;  1P8M A;  3SKK A;  4RHJ A;  1WOI A;  3TF3 A;  4GWD A;  4RHL A;  3KV2 A;  4IXU A;  4Q3S A;  1TBJ A;  3SL0 A;  1P8N A;  1TA1 A;  1WVB A;  1TBH A;  3E9B A;  1HQF A;  4Q41 A;  1HQ5 A;  3MFV A;  5RLA A;  1TBL A;  4IE3 A;  4RHK A;  3LP4 A;  1T4R A;  1GQ7 A;  3RLA A;  3LHL A;  4Q3R C;  4Q3T A;  1P8O A;  2EF5 A;  2RLA A;  1CEV A;  4RHI A;  3NIP A;  2EF4 A;  3DJ8 A;  4IU5 A;  3THE A;  4RLA A;  1GQ6 A;  2AEB A;  4IU4 A;  4HZE A;  4MYK A;  1T4T A;  4Q42 A;  4Q3U A;  4Q3Q A;  4IU0 A;  1T5G A;  3MJL A;  3MFW A;  3MMR A;  3THJ A;  4GSZ A;  5CEV A;  3M1R A;  4CEV A;  1D3V A;  3PZL A;  1HQX A;  4ITY A;  4MXR A;  4IE1 A;  3GMZ A;  1P8P A;  2EIV A;  4FCK A;  2CEV A;  4HWW A;  4IU1 A;  1P8Q A;  1R1O A;  3SJT A;  1ZPE A;  4G3H A;  4RHQ A;  1WVA A;  2A0M A;  4MYL A;  1RLA A;  1P8R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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