3E6KA

X-ray structure of human arginase i: the mutant d183a in complex with abh
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
308
structure length
308
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVAPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the specificity determinants of amino acid recognition by arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 106
structure length 308
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3e6kA00
1TBHA 4Q3UA 3RLAA 4IXVA 1XFKA 3KV2A 4I06A 2CEVA 4RHLA 2PHAA 1TA1A 1T4PA 3DJ8A 4IU0A 1HQFA 1CEVA 1WVBA 3THJA 2RLAA 4Q42A 1P8OA 3E6VA 1WOIA 3SKKA 3F80A 3E9BA 1TBLA 2PLLA 1ZPEA 3M1RA 4Q3QA 2PHOA 1WOHA 4IE1A 3SJTA 3TH7A 4MYFA 1T4RA 1T5GA 1P8SA 3MJLA 1WVAA 3GMZA 4IXUA 3LP4A 5HJAA 4RHJA 1T5FA 3MMRA 3THEA 4MYNA 1WOGA 4MYKA 4G3HA 1RLAA 3THHA 3MFVA 4Q3SA 4RHMA 3E6KA 1P8NA 4ITYA 3E8QA 1P8PA 1HQGA 4Q40A 3LP7A 4IU5A 1GQ6A 2A0MA 3LHLA 1P8QA 1TBJA 4Q3RA 4FCIA 4Q3RC 4Q41A 4RHQA 4HZEA 4Q3TA 4MYLA 1T4SA 4GWDA 1HQXA 4IE3A 3NIQA 1D3VA 1T4TA 4GSZA 4Q3VA 4HXQA 5RLAA 1PQ3A 5HJ9A 4DZ4A 2ZAVA 4Q3PA 4RHIA 4IU4A 3CEVA 3E8ZA 1P8MA 2EF4A 1HQHA 2AEBA 4CEVA 4IE2A 3SL1A 3PZLA 1ZPGA 5CEVA 1GQ7A 4RHKA 4FCKA 4MXRA 1HQ5A 3GN0A 2EF5A 4GWCA 4RLAA 1P8RA 1R1OA 4IU1A 3NIPA 3SL0A 3TF3A 4GSMA 3NIOA 4HWWA 3MFWA 2EIVA 4GSVA
chains in the Genus database with same CATH superfamily
4ZUMA 4QA1A 1TBHA 4ZUNA 5EFKB 3EZTA 4Q3UA 3RLAA 4IXVA 5THTA 1XFKA 3KV2A 4I06A 3EZPA 5G1CA 3MAXA 4CBYA 5G0HA 2CEVA 4ZUQA 4RHLA 3Q9EA 5EFGA 2PHAA 1TA1A 1W22A 5DC6A 4ZUOA 1T4PA 3DJ8A 3F06A 3F0RA 4IU0A 1HQFA 1CEVA 1WVBA 1ZZ3A 2VQMA 3THJA 2RLAA 4Q42A 1P8OA 1T64A 1WOIA 3E6VA 3SKKA 3F80A 3MZ6A 1ZZ0A 5EF8A 2V5WA 3E9BA 5G3WA 5JI5A 5HJAA 5D1CA 1TBLA 3MZ7A 3C10A 2PLLA 3Q9CA 1ZPEA 5LI3A 3M1RA 4Q3QA 2PHOA 1WOHA 1T69A 4IE1A 5G10A 5EENA 5G11A 4QA2A 3SJTA 5G0JA 3MZ3A 4QA5A 4LXZA 2VCGA 4MYFA 3TH7A 1T4RA 1T5GA 1P8SA 3MJLA 4QA0A 4QA6A 5IWGA 1WVAA 2VQOA 3GMZA 4IXUA 3LP4A 1C3RA 2VQQA 5EFNA 3EW8A 4RHJA 5EEFA 4ZURA 1T5FA 3MMRA 3SFHA 4MYNA 1WOGA 2VQWG 4G3HA 4MYKA 3THEA 3C0ZA 3ZNRA 5G17A 5IX0A 1RLAA 3THHA 4A69A 3MFVA 4CQFA 4Q3SA 4RHMA 3E6KA 4QA4A 3MZ4A 1C3SA 1P8NA 4ITYA 3E8QA 5G0IA 4BZ9A 4ZUPA 1P8PA 5G1BA 2VQJA 1HQGA 5G12A 5THUA 4Q40A 3LP7A 4IU5A 1GQ6A 4QA3A 2A0MA 3LHLA 2GH6A 1P8QA 5DC5A 3MENA 5FCWA 5D1BA 1TBJA 4Q3RA 4FCIA 5G0GA 5EFBD 4Q3RC 5EEIA 4Q41A 3C0YA 4RHQA 4RN0A 4HZEA 4Q3TA 4MYLA 1T4SA 4QA7A 4GWDA 5EEMA 1HQXA 1T67A 3RQDA 5G1AA 5THVA 3ZNSA 4IE3A 3NIQA 5FUEA 1D3VA 1T4TA 2V5XA 5THSA 4GSZA 4Q3VA 4BZ6A 4HXQA 5BWZA 5DC7A 5RLAA 1PQ3A 3Q9FA 5G13A 5HJ9A 4DZ4A 2ZAVA 4Q3PA 3EWFA 4RHIA 4IU4A 4RN2A 3CEVA 3E8ZA 4BZ5A 4BZ8A 1P8MA 2EF4A 1HQHA 1VKGA 2AEBA 3Q9BA 4BKXB 4CEVA 5A2SA 4IE2A 5EF7A 3PZLA 3SL1A 1ZPGA 5CEVA 1GQ7A 4RHKA 4FCKA 4MXRA 1HQ5A 3SFFA 3GN0A 5D1DA 2EF5A 4GWCA 4RLAA 1C3PA 1P8RA 3F07A 1R1OA 4IU1A 5EFHA 5EFJD 4BZ7A 3NIPA 3SL0A 5ICNB 2VQVA 3TF3A 1ZZ1A 4GSMA 4CBTA 4LY1A 5DC8A 3NIOA 4HWWA 3MFWA 5G0XA 4RN1A 5EEKA 2EIVA 4GSVA 5G0YA
chains in the Genus database with same CATH topology
1TBHA 4Q3UA 3RLAA 4IXVA 1XFKA 3KV2A 4I06A 2CEVA 4RHLA 2PHAA 1TA1A 1T4PA 3DJ8A 4IU0A 1HQFA 1CEVA 1WVBA 3THJA 2RLAA 4Q42A 1P8OA 3E6VA 1WOIA 3SKKA 3F80A 3E9BA 1TBLA 2PLLA 1ZPEA 3M1RA 4Q3QA 2PHOA 1WOHA 4IE1A 3SJTA 3TH7A 4MYFA 1T4RA 1T5GA 1P8SA 3MJLA 1WVAA 3GMZA 4IXUA 3LP4A 5HJAA 4RHJA 1T5FA 3MMRA 3THEA 4MYNA 1WOGA 4MYKA 4G3HA 1RLAA 3THHA 3MFVA 4Q3SA 4RHMA 3E6KA 1P8NA 4ITYA 3E8QA 1P8PA 1HQGA 4Q40A 3LP7A 4IU5A 1GQ6A 2A0MA 3LHLA 1P8QA 1TBJA 4Q3RA 4FCIA 4Q3RC 4Q41A 4RHQA 4HZEA 4Q3TA 4MYLA 1T4SA 4GWDA 1HQXA 4IE3A 3NIQA 1D3VA 1T4TA 4GSZA 4Q3VA 4HXQA 5RLAA 1PQ3A 5HJ9A 4DZ4A 2ZAVA 4Q3PA 4RHIA 4IU4A 3CEVA 3E8ZA 1P8MA 2EF4A 1HQHA 2AEBA 4CEVA 4IE2A 3SL1A 3PZLA 1ZPGA 5CEVA 1GQ7A 4RHKA 4FCKA 4MXRA 1HQ5A 3GN0A 2EF5A 4GWCA 4RLAA 1P8RA 1R1OA 4IU1A 3NIPA 3SL0A 3TF3A 4GSMA 3NIOA 4HWWA 3MFWA 2EIVA 4GSVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TBH A;  4Q3U A;  3RLA A;  4IXV A;  1XFK A;  3KV2 A;  4I06 A;  2CEV A;  4RHL A;  2PHA A;  1TA1 A;  1T4P A;  3DJ8 A;  4IU0 A;  1HQF A;  1CEV A;  1WVB A;  3THJ A;  2RLA A;  4Q42 A;  1P8O A;  3E6V A;  1WOI A;  3SKK A;  3F80 A;  3E9B A;  1TBL A;  2PLL A;  1ZPE A;  3M1R A;  4Q3Q A;  2PHO A;  1WOH A;  4IE1 A;  3SJT A;  3TH7 A;  4MYF A;  1T4R A;  1T5G A;  1P8S A;  3MJL A;  1WVA A;  3GMZ A;  4IXU A;  3LP4 A;  5HJA A;  4RHJ A;  1T5F A;  3MMR A;  3THE A;  4MYN A;  1WOG A;  4MYK A;  4G3H A;  1RLA A;  3THH A;  3MFV A;  4Q3S A;  4RHM A;  3E6K A;  1P8N A;  4ITY A;  3E8Q A;  1P8P A;  1HQG A;  4Q40 A;  3LP7 A;  4IU5 A;  1GQ6 A;  2A0M A;  3LHL A;  1P8Q A;  1TBJ A;  4Q3R A;  4FCI A;  4Q3R C;  4Q41 A;  4RHQ A;  4HZE A;  4Q3T A;  4MYL A;  1T4S A;  4GWD A;  1HQX A;  4IE3 A;  3NIQ A;  1D3V A;  1T4T A;  4GSZ A;  4Q3V A;  4HXQ A;  5RLA A;  1PQ3 A;  5HJ9 A;  4DZ4 A;  2ZAV A;  4Q3P A;  4RHI A;  4IU4 A;  3CEV A;  3E8Z A;  1P8M A;  2EF4 A;  1HQH A;  2AEB A;  4CEV A;  4IE2 A;  3SL1 A;  3PZL A;  1ZPG A;  5CEV A;  1GQ7 A;  4RHK A;  4FCK A;  4MXR A;  1HQ5 A;  3GN0 A;  2EF5 A;  4GWC A;  4RLA A;  1P8R A;  1R1O A;  4IU1 A;  3NIP A;  3SL0 A;  3TF3 A;  4GSM A;  3NIO A;  4HWW A;  3MFW A;  2EIV A;  4GSV A; 
#chains in the Genus database with same CATH topology
 4ZUM A;  4QA1 A;  1TBH A;  4ZUN A;  5EFK B;  3EZT A;  4Q3U A;  3RLA A;  4IXV A;  5THT A;  1XFK A;  3KV2 A;  4I06 A;  3EZP A;  5G1C A;  3MAX A;  4CBY A;  5G0H A;  2CEV A;  4ZUQ A;  4RHL A;  3Q9E A;  5EFG A;  2PHA A;  1TA1 A;  1W22 A;  5DC6 A;  4ZUO A;  1T4P A;  3DJ8 A;  3F06 A;  3F0R A;  4IU0 A;  1HQF A;  1CEV A;  1WVB A;  1ZZ3 A;  2VQM A;  3THJ A;  2RLA A;  4Q42 A;  1P8O A;  1T64 A;  1WOI A;  3E6V A;  3SKK A;  3F80 A;  3MZ6 A;  1ZZ0 A;  5EF8 A;  2V5W A;  3E9B A;  5G3W A;  5JI5 A;  5HJA A;  5D1C A;  1TBL A;  3MZ7 A;  3C10 A;  2PLL A;  3Q9C A;  1ZPE A;  5LI3 A;  3M1R A;  4Q3Q A;  2PHO A;  1WOH A;  1T69 A;  4IE1 A;  5G10 A;  5EEN A;  5G11 A;  4QA2 A;  3SJT A;  5G0J A;  3MZ3 A;  4QA5 A;  4LXZ A;  2VCG A;  4MYF A;  3TH7 A;  1T4R A;  1T5G A;  1P8S A;  3MJL A;  4QA0 A;  4QA6 A;  5IWG A;  1WVA A;  2VQO A;  3GMZ A;  4IXU A;  3LP4 A;  1C3R A;  2VQQ A;  5EFN A;  3EW8 A;  4RHJ A;  5EEF A;  4ZUR A;  1T5F A;  3MMR A;  3SFH A;  4MYN A;  1WOG A;  2VQW G;  4G3H A;  4MYK A;  3THE A;  3C0Z A;  3ZNR A;  5G17 A;  5IX0 A;  1RLA A;  3THH A;  4A69 A;  3MFV A;  4CQF A;  4Q3S A;  4RHM A;  3E6K A;  4QA4 A;  3MZ4 A;  1C3S A;  1P8N A;  4ITY A;  3E8Q A;  5G0I A;  4BZ9 A;  4ZUP A;  1P8P A;  5G1B A;  2VQJ A;  1HQG A;  5G12 A;  5THU A;  4Q40 A;  3LP7 A;  4IU5 A;  1GQ6 A;  4QA3 A;  2A0M A;  3LHL A;  2GH6 A;  1P8Q A;  5DC5 A;  3MEN A;  5FCW A;  5D1B A;  1TBJ A;  4Q3R A;  4FCI A;  5G0G A;  5EFB D;  4Q3R C;  5EEI A;  4Q41 A;  3C0Y A;  4RHQ A;  4RN0 A;  4HZE A;  4Q3T A;  4MYL A;  1T4S A;  4QA7 A;  4GWD A;  5EEM A;  1HQX A;  1T67 A;  3RQD A;  5G1A A;  5THV A;  3ZNS A;  4IE3 A;  3NIQ A;  5FUE A;  1D3V A;  1T4T A;  2V5X A;  5THS A;  4GSZ A;  4Q3V A;  4BZ6 A;  4HXQ A;  5BWZ A;  5DC7 A;  5RLA A;  1PQ3 A;  3Q9F A;  5G13 A;  5HJ9 A;  4DZ4 A;  2ZAV A;  4Q3P A;  3EWF A;  4RHI A;  4IU4 A;  4RN2 A;  3CEV A;  3E8Z A;  4BZ5 A;  4BZ8 A;  1P8M A;  2EF4 A;  1HQH A;  1VKG A;  2AEB A;  3Q9B A;  4BKX B;  4CEV A;  5A2S A;  4IE2 A;  5EF7 A;  3PZL A;  3SL1 A;  1ZPG A;  5CEV A;  1GQ7 A;  4RHK A;  4FCK A;  4MXR A;  1HQ5 A;  3SFF A;  3GN0 A;  5D1D A;  2EF5 A;  4GWC A;  4RLA A;  1C3P A;  1P8R A;  3F07 A;  1R1O A;  4IU1 A;  5EFH A;  5EFJ D;  4BZ7 A;  3NIP A;  3SL0 A;  5ICN B;  2VQV A;  3TF3 A;  1ZZ1 A;  4GSM A;  4CBT A;  4LY1 A;  5DC8 A;  3NIO A;  4HWW A;  3MFW A;  5G0X A;  4RN1 A;  5EEK A;  2EIV A;  4GSV A;  5G0Y A; 
#chains in the Genus database with same CATH homology
 1TBH A;  4Q3U A;  3RLA A;  4IXV A;  1XFK A;  3KV2 A;  4I06 A;  2CEV A;  4RHL A;  2PHA A;  1TA1 A;  1T4P A;  3DJ8 A;  4IU0 A;  1HQF A;  1CEV A;  1WVB A;  3THJ A;  2RLA A;  4Q42 A;  1P8O A;  3E6V A;  1WOI A;  3SKK A;  3F80 A;  3E9B A;  1TBL A;  2PLL A;  1ZPE A;  3M1R A;  4Q3Q A;  2PHO A;  1WOH A;  4IE1 A;  3SJT A;  3TH7 A;  4MYF A;  1T4R A;  1T5G A;  1P8S A;  3MJL A;  1WVA A;  3GMZ A;  4IXU A;  3LP4 A;  5HJA A;  4RHJ A;  1T5F A;  3MMR A;  3THE A;  4MYN A;  1WOG A;  4MYK A;  4G3H A;  1RLA A;  3THH A;  3MFV A;  4Q3S A;  4RHM A;  3E6K A;  1P8N A;  4ITY A;  3E8Q A;  1P8P A;  1HQG A;  4Q40 A;  3LP7 A;  4IU5 A;  1GQ6 A;  2A0M A;  3LHL A;  1P8Q A;  1TBJ A;  4Q3R A;  4FCI A;  4Q3R C;  4Q41 A;  4RHQ A;  4HZE A;  4Q3T A;  4MYL A;  1T4S A;  4GWD A;  1HQX A;  4IE3 A;  3NIQ A;  1D3V A;  1T4T A;  4GSZ A;  4Q3V A;  4HXQ A;  5RLA A;  1PQ3 A;  5HJ9 A;  4DZ4 A;  2ZAV A;  4Q3P A;  4RHI A;  4IU4 A;  3CEV A;  3E8Z A;  1P8M A;  2EF4 A;  1HQH A;  2AEB A;  4CEV A;  4IE2 A;  3SL1 A;  3PZL A;  1ZPG A;  5CEV A;  1GQ7 A;  4RHK A;  4FCK A;  4MXR A;  1HQ5 A;  3GN0 A;  2EF5 A;  4GWC A;  4RLA A;  1P8R A;  1R1O A;  4IU1 A;  3NIP A;  3SL0 A;  3TF3 A;  4GSM A;  3NIO A;  4HWW A;  3MFW A;  2EIV A;  4GSV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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