3E6VA

X-ray structure of human arginase i-d183n mutant: the complex with abh
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVNPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the specificity determinants of amino acid recognition by arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 115
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3e6vA00
3M1RA 3SL0A 1HQGA 3MFVA 4Q3TA 3THEA 1P8NA 2AEBA 3THHA 3E9BA 3THJA 4FCKA 4IE1A 3E6KA 2EIVA 4RHQA 3TF3A 1HQFA 4MYLA 1P8RA 4IE2A 4IXVA 4Q3PA 3GMZA 1ZPEA 1GQ6A 3LP4A 4GSZA 4MYKA 4Q3SA 3TH7A 1TBHA 4GSMA 3RLAA 1T4PA 4Q40A 1RLAA 4G3HA 1TA1A 2PHAA 1P8MA 1WOGA 4IE3A 3KV2A 4Q3UA 4Q3RC 4HXQA 4IU5A 4MYNA 3MJLA 3E8ZA 4CEVA 1P8SA 3LP7A 3CEVA 4HWWA 1GQ7A 4MXRA 4RHMA 4RHJA 3SJTA 4Q3QA 4RHIA 1D3VA 4RLAA 1T4TA 1T5GA 2ZAVA 3NIQA 4IU1A 3MFWA 1XFKA 2CEVA 2RLAA 3E6VA 1P8PA 1TBLA 4I06A 1T5FA 1T4RA 4MYFA 4Q3VA 3LHLA 1TBJA 4DZ4A 3MMRA 1WOHA 4Q3RA 5HJ9A 1R1OA 4ITYA 4GWDA 2PHOA 2EF5A 1T4SA 2EF4A 3NIOA 3SKKA 2PLLA 3NIPA 3SL1A 3DJ8A 3GN0A 3F80A 1HQXA 2A0MA 4Q42A 5CEVA 5RLAA 3PZLA 4IU4A 4IXUA 5HJAA 4RHKA 1WVBA 4GSVA 4GWCA 1CEVA 1ZPGA 1HQHA 4IU0A 4FCIA 4RHLA 1P8QA 1WVAA 4HZEA 1HQ5A 3E8QA 1WOIA 1P8OA 4Q41A 1PQ3A
chains in the Genus database with same CATH superfamily
3M1RA 3SL0A 4RN2A 3ZNRA 1HQGA 3MFVA 4QA7A 4Q3TA 1W22A 3THEA 2V5WA 1P8NA 2AEBA 4QA3A 5G12A 5G17A 3EZPA 3MZ7A 3E9BA 5EEKA 3THHA 2VQJA 3THJA 3C10A 3Q9CA 4FCKA 4IE1A 1C3PA 3E6KA 2VQVA 2EIVA 5EENA 3MAXA 4ZUPA 4RHQA 5FUEA 3EWFA 5IWGA 3TF3A 1HQFA 4LY1A 1T67A 4MYLA 1P8RA 4IE2A 5FCWA 5EFJD 5G11A 5DC8A 4IXVA 4Q3PA 3GMZA 1ZPEA 3Q9BA 4A69A 1GQ6A 3LP4A 4GSZA 4MYKA 4Q3SA 5G1AA 1TBHA 4GSMA 3RLAA 3TH7A 1T4PA 3EW8A 2VQMA 4Q40A 5G0HA 1RLAA 4G3HA 1TA1A 2PHAA 1P8MA 1WOGA 4IE3A 3KV2A 4Q3UA 4Q3RC 1C3SA 5EF8A 4HXQA 4IU5A 4MYNA 5IX0A 3MJLA 5G1BA 3E8ZA 4CEVA 4RN1A 2VCGA 1P8SA 3LP7A 3CEVA 4HWWA 5EFGA 1GQ7A 5DC5A 5G0YA 4MXRA 4RHMA 4RHJA 4BZ7A 3SJTA 2V5XA 4Q3QA 3MZ4A 4RHIA 5DC7A 1D3VA 4RLAA 1T4TA 1T5GA 2ZAVA 3NIQA 4IU1A 4QA0A 3MFWA 4ZURA 5BWZA 4CBYA 1XFKA 5G0JA 2CEVA 2RLAA 1ZZ1A 4CQFA 5EFHA 3E6VA 1P8PA 1TBLA 3C0ZA 4I06A 5D1CA 1ZZ3A 1T5FA 1T4RA 5THVA 3RQDA 4MYFA 4Q3VA 4BZ5A 3LHLA 5EEMA 3Q9EA 5THUA 5D1DA 1TBJA 5JI5A 4DZ4A 5EFNA 5G0GA 5ICNB 3MMRA 1WOHA 4Q3RA 1ZZ0A 4ZUOA 5HJ9A 1R1OA 4BZ9A 4ITYA 4GWDA 4BZ6A 2PHOA 2EF5A 5EFKB 3MENA 1T4SA 5LI3A 2EF4A 3NIOA 5EF7A 3SFFA 5EEFA 3SKKA 4ZUQA 2PLLA 4BZ8A 3MZ6A 3NIPA 3SL1A 3DJ8A 4CBTA 3GN0A 3SFHA 5G0XA 3F80A 1HQXA 2A0MA 4Q42A 5CEVA 5G13A 2GH6A 5RLAA 5G3WA 3F07A 4QA5A 5G1CA 3F06A 3MZ3A 3PZLA 5THTA 4BKXB 1T64A 5G0IA 4IU4A 4IXUA 3F0RA 5D1BA 1C3RA 4QA2A 5HJAA 4ZUMA 4RHKA 1WVBA 3C0YA 4GSVA 4QA6A 4GWCA 3Q9FA 5G10A 1CEVA 5DC6A 1ZPGA 2VQWG 1HQHA 5EFBD 4IU0A 1T69A 1VKGA 3EZTA 4FCIA 5EEIA 3ZNSA 5A2SA 4RHLA 1P8QA 1WVAA 4QA4A 4ZUNA 4HZEA 1HQ5A 2VQQA 3E8QA 4QA1A 2VQOA 4LXZA 4RN0A 1WOIA 5THSA 1P8OA 4Q41A 1PQ3A
chains in the Genus database with same CATH topology
3M1RA 3SL0A 1HQGA 3MFVA 4Q3TA 3THEA 1P8NA 2AEBA 3THHA 3E9BA 3THJA 4FCKA 4IE1A 3E6KA 2EIVA 4RHQA 3TF3A 1HQFA 4MYLA 1P8RA 4IE2A 4IXVA 4Q3PA 3GMZA 1ZPEA 1GQ6A 3LP4A 4GSZA 4MYKA 4Q3SA 3TH7A 1TBHA 4GSMA 3RLAA 1T4PA 4Q40A 1RLAA 4G3HA 1TA1A 2PHAA 1P8MA 1WOGA 4IE3A 3KV2A 4Q3UA 4Q3RC 4HXQA 4IU5A 4MYNA 3MJLA 3E8ZA 4CEVA 1P8SA 3LP7A 3CEVA 4HWWA 1GQ7A 4MXRA 4RHMA 4RHJA 3SJTA 4Q3QA 4RHIA 1D3VA 4RLAA 1T4TA 1T5GA 2ZAVA 3NIQA 4IU1A 3MFWA 1XFKA 2CEVA 2RLAA 3E6VA 1P8PA 1TBLA 4I06A 1T5FA 1T4RA 4MYFA 4Q3VA 3LHLA 1TBJA 4DZ4A 3MMRA 1WOHA 4Q3RA 5HJ9A 1R1OA 4ITYA 4GWDA 2PHOA 2EF5A 1T4SA 2EF4A 3NIOA 3SKKA 2PLLA 3NIPA 3SL1A 3DJ8A 3GN0A 3F80A 1HQXA 2A0MA 4Q42A 5CEVA 5RLAA 3PZLA 4IU4A 4IXUA 5HJAA 4RHKA 1WVBA 4GSVA 4GWCA 1CEVA 1ZPGA 1HQHA 4IU0A 4FCIA 4RHLA 1P8QA 1WVAA 4HZEA 1HQ5A 3E8QA 1WOIA 1P8OA 4Q41A 1PQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M1R A;  3SL0 A;  1HQG A;  3MFV A;  4Q3T A;  3THE A;  1P8N A;  2AEB A;  3THH A;  3E9B A;  3THJ A;  4FCK A;  4IE1 A;  3E6K A;  2EIV A;  4RHQ A;  3TF3 A;  1HQF A;  4MYL A;  1P8R A;  4IE2 A;  4IXV A;  4Q3P A;  3GMZ A;  1ZPE A;  1GQ6 A;  3LP4 A;  4GSZ A;  4MYK A;  4Q3S A;  3TH7 A;  1TBH A;  4GSM A;  3RLA A;  1T4P A;  4Q40 A;  1RLA A;  4G3H A;  1TA1 A;  2PHA A;  1P8M A;  1WOG A;  4IE3 A;  3KV2 A;  4Q3U A;  4Q3R C;  4HXQ A;  4IU5 A;  4MYN A;  3MJL A;  3E8Z A;  4CEV A;  1P8S A;  3LP7 A;  3CEV A;  4HWW A;  1GQ7 A;  4MXR A;  4RHM A;  4RHJ A;  3SJT A;  4Q3Q A;  4RHI A;  1D3V A;  4RLA A;  1T4T A;  1T5G A;  2ZAV A;  3NIQ A;  4IU1 A;  3MFW A;  1XFK A;  2CEV A;  2RLA A;  3E6V A;  1P8P A;  1TBL A;  4I06 A;  1T5F A;  1T4R A;  4MYF A;  4Q3V A;  3LHL A;  1TBJ A;  4DZ4 A;  3MMR A;  1WOH A;  4Q3R A;  5HJ9 A;  1R1O A;  4ITY A;  4GWD A;  2PHO A;  2EF5 A;  1T4S A;  2EF4 A;  3NIO A;  3SKK A;  2PLL A;  3NIP A;  3SL1 A;  3DJ8 A;  3GN0 A;  3F80 A;  1HQX A;  2A0M A;  4Q42 A;  5CEV A;  5RLA A;  3PZL A;  4IU4 A;  4IXU A;  5HJA A;  4RHK A;  1WVB A;  4GSV A;  4GWC A;  1CEV A;  1ZPG A;  1HQH A;  4IU0 A;  4FCI A;  4RHL A;  1P8Q A;  1WVA A;  4HZE A;  1HQ5 A;  3E8Q A;  1WOI A;  1P8O A;  4Q41 A;  1PQ3 A; 
#chains in the Genus database with same CATH topology
 3M1R A;  3SL0 A;  4RN2 A;  3ZNR A;  1HQG A;  3MFV A;  4QA7 A;  4Q3T A;  1W22 A;  3THE A;  2V5W A;  1P8N A;  2AEB A;  4QA3 A;  5G12 A;  5G17 A;  3EZP A;  3MZ7 A;  3E9B A;  5EEK A;  3THH A;  2VQJ A;  3THJ A;  3C10 A;  3Q9C A;  4FCK A;  4IE1 A;  1C3P A;  3E6K A;  2VQV A;  2EIV A;  5EEN A;  3MAX A;  4ZUP A;  4RHQ A;  5FUE A;  3EWF A;  5IWG A;  3TF3 A;  1HQF A;  4LY1 A;  1T67 A;  4MYL A;  1P8R A;  4IE2 A;  5FCW A;  5EFJ D;  5G11 A;  5DC8 A;  4IXV A;  4Q3P A;  3GMZ A;  1ZPE A;  3Q9B A;  4A69 A;  1GQ6 A;  3LP4 A;  4GSZ A;  4MYK A;  4Q3S A;  5G1A A;  1TBH A;  4GSM A;  3RLA A;  3TH7 A;  1T4P A;  3EW8 A;  2VQM A;  4Q40 A;  5G0H A;  1RLA A;  4G3H A;  1TA1 A;  2PHA A;  1P8M A;  1WOG A;  4IE3 A;  3KV2 A;  4Q3U A;  4Q3R C;  1C3S A;  5EF8 A;  4HXQ A;  4IU5 A;  4MYN A;  5IX0 A;  3MJL A;  5G1B A;  3E8Z A;  4CEV A;  4RN1 A;  2VCG A;  1P8S A;  3LP7 A;  3CEV A;  4HWW A;  5EFG A;  1GQ7 A;  5DC5 A;  5G0Y A;  4MXR A;  4RHM A;  4RHJ A;  4BZ7 A;  3SJT A;  2V5X A;  4Q3Q A;  3MZ4 A;  4RHI A;  5DC7 A;  1D3V A;  4RLA A;  1T4T A;  1T5G A;  2ZAV A;  3NIQ A;  4IU1 A;  4QA0 A;  3MFW A;  4ZUR A;  5BWZ A;  4CBY A;  1XFK A;  5G0J A;  2CEV A;  2RLA A;  1ZZ1 A;  4CQF A;  5EFH A;  3E6V A;  1P8P A;  1TBL A;  3C0Z A;  4I06 A;  5D1C A;  1ZZ3 A;  1T5F A;  1T4R A;  5THV A;  3RQD A;  4MYF A;  4Q3V A;  4BZ5 A;  3LHL A;  5EEM A;  3Q9E A;  5THU A;  5D1D A;  1TBJ A;  5JI5 A;  4DZ4 A;  5EFN A;  5G0G A;  5ICN B;  3MMR A;  1WOH A;  4Q3R A;  1ZZ0 A;  4ZUO A;  5HJ9 A;  1R1O A;  4BZ9 A;  4ITY A;  4GWD A;  4BZ6 A;  2PHO A;  2EF5 A;  5EFK B;  3MEN A;  1T4S A;  5LI3 A;  2EF4 A;  3NIO A;  5EF7 A;  3SFF A;  5EEF A;  3SKK A;  4ZUQ A;  2PLL A;  4BZ8 A;  3MZ6 A;  3NIP A;  3SL1 A;  3DJ8 A;  4CBT A;  3GN0 A;  3SFH A;  5G0X A;  3F80 A;  1HQX A;  2A0M A;  4Q42 A;  5CEV A;  5G13 A;  2GH6 A;  5RLA A;  5G3W A;  3F07 A;  4QA5 A;  5G1C A;  3F06 A;  3MZ3 A;  3PZL A;  5THT A;  4BKX B;  1T64 A;  5G0I A;  4IU4 A;  4IXU A;  3F0R A;  5D1B A;  1C3R A;  4QA2 A;  5HJA A;  4ZUM A;  4RHK A;  1WVB A;  3C0Y A;  4GSV A;  4QA6 A;  4GWC A;  3Q9F A;  5G10 A;  1CEV A;  5DC6 A;  1ZPG A;  2VQW G;  1HQH A;  5EFB D;  4IU0 A;  1T69 A;  1VKG A;  3EZT A;  4FCI A;  5EEI A;  3ZNS A;  5A2S A;  4RHL A;  1P8Q A;  1WVA A;  4QA4 A;  4ZUN A;  4HZE A;  1HQ5 A;  2VQQ A;  3E8Q A;  4QA1 A;  2VQO A;  4LXZ A;  4RN0 A;  1WOI A;  5THS A;  1P8O A;  4Q41 A;  1PQ3 A; 
#chains in the Genus database with same CATH homology
 3M1R A;  3SL0 A;  1HQG A;  3MFV A;  4Q3T A;  3THE A;  1P8N A;  2AEB A;  3THH A;  3E9B A;  3THJ A;  4FCK A;  4IE1 A;  3E6K A;  2EIV A;  4RHQ A;  3TF3 A;  1HQF A;  4MYL A;  1P8R A;  4IE2 A;  4IXV A;  4Q3P A;  3GMZ A;  1ZPE A;  1GQ6 A;  3LP4 A;  4GSZ A;  4MYK A;  4Q3S A;  3TH7 A;  1TBH A;  4GSM A;  3RLA A;  1T4P A;  4Q40 A;  1RLA A;  4G3H A;  1TA1 A;  2PHA A;  1P8M A;  1WOG A;  4IE3 A;  3KV2 A;  4Q3U A;  4Q3R C;  4HXQ A;  4IU5 A;  4MYN A;  3MJL A;  3E8Z A;  4CEV A;  1P8S A;  3LP7 A;  3CEV A;  4HWW A;  1GQ7 A;  4MXR A;  4RHM A;  4RHJ A;  3SJT A;  4Q3Q A;  4RHI A;  1D3V A;  4RLA A;  1T4T A;  1T5G A;  2ZAV A;  3NIQ A;  4IU1 A;  3MFW A;  1XFK A;  2CEV A;  2RLA A;  3E6V A;  1P8P A;  1TBL A;  4I06 A;  1T5F A;  1T4R A;  4MYF A;  4Q3V A;  3LHL A;  1TBJ A;  4DZ4 A;  3MMR A;  1WOH A;  4Q3R A;  5HJ9 A;  1R1O A;  4ITY A;  4GWD A;  2PHO A;  2EF5 A;  1T4S A;  2EF4 A;  3NIO A;  3SKK A;  2PLL A;  3NIP A;  3SL1 A;  3DJ8 A;  3GN0 A;  3F80 A;  1HQX A;  2A0M A;  4Q42 A;  5CEV A;  5RLA A;  3PZL A;  4IU4 A;  4IXU A;  5HJA A;  4RHK A;  1WVB A;  4GSV A;  4GWC A;  1CEV A;  1ZPG A;  1HQH A;  4IU0 A;  4FCI A;  4RHL A;  1P8Q A;  1WVA A;  4HZE A;  1HQ5 A;  3E8Q A;  1WOI A;  1P8O A;  4Q41 A;  1PQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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