3E8QA

X-ray structure of rat arginase i-t135a: the unliganded complex
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
308
structure length
308
Chain Sequence
KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTASSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the specificity determinants of amino acid recognition by arginase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Arginase-1
total genus 101
structure length 308
sequence length 308
chains with identical sequence B, C
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3e8qA00
1HQ5A 3SL0A 1R1OA 4IU5A 5RLAA 4RHMA 3E6KA 2ZAVA 1T5GA 2EIVA 1T5FA 3E8ZA 4Q3RA 4Q3RC 4IE3A 4IU1A 1WVAA 4MYFA 1HQGA 4CEVA 3E8QA 4RHLA 2AEBA 1TBHA 2PHAA 3THJA 4RHIA 4HXQA 1P8RA 1WOGA 2EF5A 3NIOA 3RLAA 1TBLA 4RHJA 1TBJA 4IU4A 4RHQA 5HJAA 4IXUA 4ITYA 4RHKA 1D3VA 4GSZA 4Q3QA 4Q41A 3LP4A 1P8PA 1XFKA 1GQ7A 4MYNA 3SKKA 1T4RA 3NIPA 1HQFA 4GSVA 3GN0A 1P8OA 1P8SA 3E9BA 4Q3PA 3MFWA 2RLAA 4HZEA 1GQ6A 3THHA 1WOIA 4Q3VA 1ZPGA 3CEVA 3F80A 5CEVA 3DJ8A 1WOHA 4RLAA 1HQXA 4IXVA 3E6VA 1P8NA 3GMZA 4Q3UA 4IE1A 1RLAA 3KV2A 4Q3TA 3NIQA 3LP7A 4MXRA 4FCIA 4IU0A 3MJLA 3TH7A 4I06A 4HWWA 1CEVA 4MYKA 1WVBA 2A0MA 1T4SA 4GWCA 4Q3SA 4Q40A 2EF4A 4FCKA 1T4TA 2CEVA 3SL1A 3MMRA 4G3HA 4Q42A 1PQ3A 3TF3A 1TA1A 3MFVA 1ZPEA 1P8MA 5HJ9A 4GSMA 4MYLA 4DZ4A 1HQHA 4IE2A 3SJTA 1P8QA 3M1RA 1T4PA 3LHLA 2PLLA 4GWDA 3THEA 3PZLA 2PHOA
chains in the Genus database with same CATH superfamily
1VKGA 1HQ5A 3SL0A 1R1OA 4IU5A 5JI5A 3C10A 3ZNSA 5RLAA 4BZ6A 4RHMA 3E6KA 3MZ4A 4ZUNA 5EF7A 3RQDA 3F06A 3MZ7A 4ZUPA 3MAXA 5EEIA 2ZAVA 1T5GA 2EIVA 5G12A 1T5FA 1T64A 1ZZ1A 2VQMA 3E8ZA 4CBTA 3C0ZA 4Q3RA 5G1CA 3MZ6A 4Q3RC 4QA5A 5DC7A 5FCWA 4IE3A 4IU1A 4RN1A 4CBYA 1WVAA 4MYFA 1ZZ0A 1HQGA 4CEVA 5G1BA 5G0JA 3E8QA 4QA4A 4RHLA 5DC8A 1C3RA 2GH6A 2AEBA 1TBHA 2PHAA 5EFKB 3THJA 4RHIA 5IX0A 3Q9FA 3EWFA 1P8RA 3EZPA 4HXQA 5THVA 5EFHA 1WOGA 2EF5A 5EF8A 3MENA 3MZ3A 3F0RA 3NIOA 3RLAA 1TBLA 4RHJA 5THTA 1TBJA 5DC5A 4IU4A 4RHQA 5HJAA 5EFGA 4IXUA 5G0GA 4ITYA 1W22A 4RHKA 1D3VA 4GSZA 3Q9EA 4Q3QA 5BWZA 4Q41A 3LP4A 1P8PA 1XFKA 5THSA 4RN2A 1GQ7A 4MYNA 5EENA 3SKKA 4A69A 1T4RA 3NIPA 1HQFA 5G17A 4BKXB 4GSVA 3GN0A 1P8OA 5EFNA 1P8SA 5EEFA 4ZUOA 3E9BA 4Q3PA 3MFWA 3ZNRA 2RLAA 4HZEA 1GQ6A 4LXZA 1C3SA 1WOIA 3C0YA 5FUEA 4Q3VA 3THHA 5D1BA 1ZPGA 3CEVA 3F80A 5CEVA 3DJ8A 5EEMA 4QA7A 1WOHA 5D1DA 4BZ8A 5EFBD 1T69A 4RLAA 1HQXA 1ZZ3A 4IXVA 3E6VA 1P8NA 1C3PA 3GMZA 4Q3UA 5G1AA 4BZ9A 4IE1A 1RLAA 3EZTA 3KV2A 4Q3TA 5A2SA 3NIQA 3LP7A 2V5XA 4MXRA 4FCIA 4BZ5A 5THUA 4IU0A 3MJLA 5DC6A 4I06A 4HWWA 1T67A 3TH7A 4BZ7A 1CEVA 2VQQA 2VQJA 4LY1A 4MYKA 5G11A 1WVBA 3EW8A 2A0MA 4ZUQA 4QA6A 1T4SA 4GWCA 4Q3SA 5LI3A 2VQVA 4Q40A 2V5WA 5G0IA 2EF4A 4FCKA 3SFHA 5G0HA 1T4TA 5G13A 2CEVA 5EEKA 3F07A 3SL1A 3MMRA 2VCGA 4QA1A 4G3HA 4Q42A 1PQ3A 4QA0A 3Q9CA 3TF3A 1TA1A 3MFVA 5G3WA 1ZPEA 1P8MA 5HJ9A 5D1CA 4GSMA 4RN0A 5ICNB 5EFJD 4ZURA 4MYLA 4DZ4A 1HQHA 4IE2A 3SJTA 1P8QA 3M1RA 1T4PA 3Q9BA 5G0YA 4ZUMA 4CQFA 3LHLA 4QA3A 2PLLA 4GWDA 2VQWG 5G0XA 4QA2A 5G10A 5IWGA 3THEA 2VQOA 3SFFA 3PZLA 2PHOA
chains in the Genus database with same CATH topology
1HQ5A 3SL0A 1R1OA 4IU5A 5RLAA 4RHMA 3E6KA 2ZAVA 1T5GA 2EIVA 1T5FA 3E8ZA 4Q3RA 4Q3RC 4IE3A 4IU1A 1WVAA 4MYFA 1HQGA 4CEVA 3E8QA 4RHLA 2AEBA 1TBHA 2PHAA 3THJA 4RHIA 4HXQA 1P8RA 1WOGA 2EF5A 3NIOA 3RLAA 1TBLA 4RHJA 1TBJA 4IU4A 4RHQA 5HJAA 4IXUA 4ITYA 4RHKA 1D3VA 4GSZA 4Q3QA 4Q41A 3LP4A 1P8PA 1XFKA 1GQ7A 4MYNA 3SKKA 1T4RA 3NIPA 1HQFA 4GSVA 3GN0A 1P8OA 1P8SA 3E9BA 4Q3PA 3MFWA 2RLAA 4HZEA 1GQ6A 3THHA 1WOIA 4Q3VA 1ZPGA 3CEVA 3F80A 5CEVA 3DJ8A 1WOHA 4RLAA 1HQXA 4IXVA 3E6VA 1P8NA 3GMZA 4Q3UA 4IE1A 1RLAA 3KV2A 4Q3TA 3NIQA 3LP7A 4MXRA 4FCIA 4IU0A 3MJLA 3TH7A 4I06A 4HWWA 1CEVA 4MYKA 1WVBA 2A0MA 1T4SA 4GWCA 4Q3SA 4Q40A 2EF4A 4FCKA 1T4TA 2CEVA 3SL1A 3MMRA 4G3HA 4Q42A 1PQ3A 3TF3A 1TA1A 3MFVA 1ZPEA 1P8MA 5HJ9A 4GSMA 4MYLA 4DZ4A 1HQHA 4IE2A 3SJTA 1P8QA 3M1RA 1T4PA 3LHLA 2PLLA 4GWDA 3THEA 3PZLA 2PHOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HQ5 A;  3SL0 A;  1R1O A;  4IU5 A;  5RLA A;  4RHM A;  3E6K A;  2ZAV A;  1T5G A;  2EIV A;  1T5F A;  3E8Z A;  4Q3R A;  4Q3R C;  4IE3 A;  4IU1 A;  1WVA A;  4MYF A;  1HQG A;  4CEV A;  3E8Q A;  4RHL A;  2AEB A;  1TBH A;  2PHA A;  3THJ A;  4RHI A;  4HXQ A;  1P8R A;  1WOG A;  2EF5 A;  3NIO A;  3RLA A;  1TBL A;  4RHJ A;  1TBJ A;  4IU4 A;  4RHQ A;  5HJA A;  4IXU A;  4ITY A;  4RHK A;  1D3V A;  4GSZ A;  4Q3Q A;  4Q41 A;  3LP4 A;  1P8P A;  1XFK A;  1GQ7 A;  4MYN A;  3SKK A;  1T4R A;  3NIP A;  1HQF A;  4GSV A;  3GN0 A;  1P8O A;  1P8S A;  3E9B A;  4Q3P A;  3MFW A;  2RLA A;  4HZE A;  1GQ6 A;  3THH A;  1WOI A;  4Q3V A;  1ZPG A;  3CEV A;  3F80 A;  5CEV A;  3DJ8 A;  1WOH A;  4RLA A;  1HQX A;  4IXV A;  3E6V A;  1P8N A;  3GMZ A;  4Q3U A;  4IE1 A;  1RLA A;  3KV2 A;  4Q3T A;  3NIQ A;  3LP7 A;  4MXR A;  4FCI A;  4IU0 A;  3MJL A;  3TH7 A;  4I06 A;  4HWW A;  1CEV A;  4MYK A;  1WVB A;  2A0M A;  1T4S A;  4GWC A;  4Q3S A;  4Q40 A;  2EF4 A;  4FCK A;  1T4T A;  2CEV A;  3SL1 A;  3MMR A;  4G3H A;  4Q42 A;  1PQ3 A;  3TF3 A;  1TA1 A;  3MFV A;  1ZPE A;  1P8M A;  5HJ9 A;  4GSM A;  4MYL A;  4DZ4 A;  1HQH A;  4IE2 A;  3SJT A;  1P8Q A;  3M1R A;  1T4P A;  3LHL A;  2PLL A;  4GWD A;  3THE A;  3PZL A;  2PHO A; 
#chains in the Genus database with same CATH topology
 1VKG A;  1HQ5 A;  3SL0 A;  1R1O A;  4IU5 A;  5JI5 A;  3C10 A;  3ZNS A;  5RLA A;  4BZ6 A;  4RHM A;  3E6K A;  3MZ4 A;  4ZUN A;  5EF7 A;  3RQD A;  3F06 A;  3MZ7 A;  4ZUP A;  3MAX A;  5EEI A;  2ZAV A;  1T5G A;  2EIV A;  5G12 A;  1T5F A;  1T64 A;  1ZZ1 A;  2VQM A;  3E8Z A;  4CBT A;  3C0Z A;  4Q3R A;  5G1C A;  3MZ6 A;  4Q3R C;  4QA5 A;  5DC7 A;  5FCW A;  4IE3 A;  4IU1 A;  4RN1 A;  4CBY A;  1WVA A;  4MYF A;  1ZZ0 A;  1HQG A;  4CEV A;  5G1B A;  5G0J A;  3E8Q A;  4QA4 A;  4RHL A;  5DC8 A;  1C3R A;  2GH6 A;  2AEB A;  1TBH A;  2PHA A;  5EFK B;  3THJ A;  4RHI A;  5IX0 A;  3Q9F A;  3EWF A;  1P8R A;  3EZP A;  4HXQ A;  5THV A;  5EFH A;  1WOG A;  2EF5 A;  5EF8 A;  3MEN A;  3MZ3 A;  3F0R A;  3NIO A;  3RLA A;  1TBL A;  4RHJ A;  5THT A;  1TBJ A;  5DC5 A;  4IU4 A;  4RHQ A;  5HJA A;  5EFG A;  4IXU A;  5G0G A;  4ITY A;  1W22 A;  4RHK A;  1D3V A;  4GSZ A;  3Q9E A;  4Q3Q A;  5BWZ A;  4Q41 A;  3LP4 A;  1P8P A;  1XFK A;  5THS A;  4RN2 A;  1GQ7 A;  4MYN A;  5EEN A;  3SKK A;  4A69 A;  1T4R A;  3NIP A;  1HQF A;  5G17 A;  4BKX B;  4GSV A;  3GN0 A;  1P8O A;  5EFN A;  1P8S A;  5EEF A;  4ZUO A;  3E9B A;  4Q3P A;  3MFW A;  3ZNR A;  2RLA A;  4HZE A;  1GQ6 A;  4LXZ A;  1C3S A;  1WOI A;  3C0Y A;  5FUE A;  4Q3V A;  3THH A;  5D1B A;  1ZPG A;  3CEV A;  3F80 A;  5CEV A;  3DJ8 A;  5EEM A;  4QA7 A;  1WOH A;  5D1D A;  4BZ8 A;  5EFB D;  1T69 A;  4RLA A;  1HQX A;  1ZZ3 A;  4IXV A;  3E6V A;  1P8N A;  1C3P A;  3GMZ A;  4Q3U A;  5G1A A;  4BZ9 A;  4IE1 A;  1RLA A;  3EZT A;  3KV2 A;  4Q3T A;  5A2S A;  3NIQ A;  3LP7 A;  2V5X A;  4MXR A;  4FCI A;  4BZ5 A;  5THU A;  4IU0 A;  3MJL A;  5DC6 A;  4I06 A;  4HWW A;  1T67 A;  3TH7 A;  4BZ7 A;  1CEV A;  2VQQ A;  2VQJ A;  4LY1 A;  4MYK A;  5G11 A;  1WVB A;  3EW8 A;  2A0M A;  4ZUQ A;  4QA6 A;  1T4S A;  4GWC A;  4Q3S A;  5LI3 A;  2VQV A;  4Q40 A;  2V5W A;  5G0I A;  2EF4 A;  4FCK A;  3SFH A;  5G0H A;  1T4T A;  5G13 A;  2CEV A;  5EEK A;  3F07 A;  3SL1 A;  3MMR A;  2VCG A;  4QA1 A;  4G3H A;  4Q42 A;  1PQ3 A;  4QA0 A;  3Q9C A;  3TF3 A;  1TA1 A;  3MFV A;  5G3W A;  1ZPE A;  1P8M A;  5HJ9 A;  5D1C A;  4GSM A;  4RN0 A;  5ICN B;  5EFJ D;  4ZUR A;  4MYL A;  4DZ4 A;  1HQH A;  4IE2 A;  3SJT A;  1P8Q A;  3M1R A;  1T4P A;  3Q9B A;  5G0Y A;  4ZUM A;  4CQF A;  3LHL A;  4QA3 A;  2PLL A;  4GWD A;  2VQW G;  5G0X A;  4QA2 A;  5G10 A;  5IWG A;  3THE A;  2VQO A;  3SFF A;  3PZL A;  2PHO A; 
#chains in the Genus database with same CATH homology
 1HQ5 A;  3SL0 A;  1R1O A;  4IU5 A;  5RLA A;  4RHM A;  3E6K A;  2ZAV A;  1T5G A;  2EIV A;  1T5F A;  3E8Z A;  4Q3R A;  4Q3R C;  4IE3 A;  4IU1 A;  1WVA A;  4MYF A;  1HQG A;  4CEV A;  3E8Q A;  4RHL A;  2AEB A;  1TBH A;  2PHA A;  3THJ A;  4RHI A;  4HXQ A;  1P8R A;  1WOG A;  2EF5 A;  3NIO A;  3RLA A;  1TBL A;  4RHJ A;  1TBJ A;  4IU4 A;  4RHQ A;  5HJA A;  4IXU A;  4ITY A;  4RHK A;  1D3V A;  4GSZ A;  4Q3Q A;  4Q41 A;  3LP4 A;  1P8P A;  1XFK A;  1GQ7 A;  4MYN A;  3SKK A;  1T4R A;  3NIP A;  1HQF A;  4GSV A;  3GN0 A;  1P8O A;  1P8S A;  3E9B A;  4Q3P A;  3MFW A;  2RLA A;  4HZE A;  1GQ6 A;  3THH A;  1WOI A;  4Q3V A;  1ZPG A;  3CEV A;  3F80 A;  5CEV A;  3DJ8 A;  1WOH A;  4RLA A;  1HQX A;  4IXV A;  3E6V A;  1P8N A;  3GMZ A;  4Q3U A;  4IE1 A;  1RLA A;  3KV2 A;  4Q3T A;  3NIQ A;  3LP7 A;  4MXR A;  4FCI A;  4IU0 A;  3MJL A;  3TH7 A;  4I06 A;  4HWW A;  1CEV A;  4MYK A;  1WVB A;  2A0M A;  1T4S A;  4GWC A;  4Q3S A;  4Q40 A;  2EF4 A;  4FCK A;  1T4T A;  2CEV A;  3SL1 A;  3MMR A;  4G3H A;  4Q42 A;  1PQ3 A;  3TF3 A;  1TA1 A;  3MFV A;  1ZPE A;  1P8M A;  5HJ9 A;  4GSM A;  4MYL A;  4DZ4 A;  1HQH A;  4IE2 A;  3SJT A;  1P8Q A;  3M1R A;  1T4P A;  3LHL A;  2PLL A;  4GWD A;  3THE A;  3PZL A;  2PHO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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