3F80A

(s)-2-amino-6-nitrohexanoic acid binds to human arginase i through multiple nitro-metal coordination interactions in the binuclear manganese cluster. resolution 1.60 a.
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
313
structure length
313
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title (S)-2-Amino-6-nitrohexanoic Acid Binds to Human Arginase I through Multiple Nitro-Metal Coordination Interactions in the Binuclear Manganese Cluster.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 114
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2008-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3f80A00
4IE2A 3E8ZA 1ZPEA 1T4TA 2ZAVA 2RLAA 4GSVA 4RHKA 3CEVA 1P8PA 4FCIA 4RLAA 4CEVA 3KV2A 1P8QA 4HWWA 3MJLA 1T4SA 3THHA 1D3VA 5HJAA 1HQGA 1P8SA 1HQHA 3SJTA 3GMZA 5RLAA 3TH7A 1WOIA 3E8QA 1TBLA 3NIOA 4GSMA 1GQ7A 4IU0A 3SKKA 1RLAA 4RHLA 1HQFA 4Q3PA 4HXQA 1WVBA 4IU5A 5HJ9A 4Q3QA 4I06A 3LHLA 4RHIA 5CEVA 4Q3RA 1ZPGA 1CEVA 4Q3UA 4FCKA 4ITYA 2EIVA 4MYNA 1WOHA 3LP4A 3THJA 3TF3A 3SL1A 3RLAA 4Q3SA 4MYLA 1TA1A 3MMRA 4IXVA 2AEBA 3LP7A 2CEVA 1HQXA 4G3HA 1PQ3A 4Q3VA 4RHMA 3THEA 2EF4A 3E9BA 3SL0A 3GN0A 4HZEA 4GWDA 1TBJA 3PZLA 3NIQA 1GQ6A 4Q3TA 4IXUA 1WVAA 1WOGA 3DJ8A 4IE1A 4Q42A 1HQ5A 4Q3RC 3E6VA 3MFWA 1T5FA 1TBHA 3MFVA 3NIPA 1P8RA 3M1RA 4MYFA 4Q40A 4GSZA 4RHQA 4Q41A 3E6KA 4RHJA 1T4PA 1T4RA 2PHAA 4IU1A 4IU4A 4MYKA 1P8MA 4GWCA 3F80A 1XFKA 2A0MA 2EF5A 2PHOA 1P8OA 1P8NA 1R1OA 1T5GA 4IE3A 4MXRA 2PLLA 4DZ4A
chains in the Genus database with same CATH superfamily
4BZ7A 4IE2A 4DZ4A 3E8ZA 1ZPEA 1T4TA 2ZAVA 5G12A 2RLAA 4GSVA 3F0RA 5EF7A 2VQOA 3MZ4A 4RHKA 5EFNA 5D1DA 5G1BA 3CEVA 1P8PA 4FCIA 4RLAA 1W22A 4BKXB 3KV2A 4CEVA 5EEFA 1P8QA 4HWWA 3MJLA 1T4SA 3THHA 1D3VA 4QA7A 5HJAA 5G17A 3EZPA 3Q9EA 3RQDA 4CBTA 5G0HA 1HQGA 1P8SA 4LY1A 1HQHA 1T69A 3SJTA 3GMZA 5LI3A 3THEA 5RLAA 3TH7A 4QA2A 1ZZ1A 5A2SA 1WOIA 3E8QA 1TBLA 3NIOA 5G11A 4ZUQA 4GSMA 1GQ7A 4IU0A 3SKKA 1RLAA 4RHLA 1HQFA 5G0JA 4Q3PA 4HXQA 1WVBA 4IU5A 5HJ9A 4Q3QA 3F06A 5THVA 4I06A 3LHLA 5EEMA 4RHIA 3ZNRA 1VKGA 5CEVA 3MZ3A 4Q3RA 4RN2A 1ZPGA 5JI5A 3SFFA 1ZZ0A 1ZZ3A 1CEVA 5EENA 3EWFA 4Q3UA 4FCKA 4ITYA 2EIVA 3MAXA 4MYNA 4QA5A 1WOHA 4QA1A 4ZUMA 5BWZA 4CQFA 3Q9BA 3LP4A 4RN1A 3THJA 5G0XA 5DC6A 3TF3A 4QA6A 3C0ZA 5EEIA 3SL1A 3RLAA 2VQVA 4Q3SA 5G1AA 5IWGA 4MYLA 1C3SA 1TA1A 3MMRA 4IXVA 2AEBA 3LP7A 2CEVA 1HQXA 4G3HA 1PQ3A 4Q3VA 4RHMA 5G0IA 3EW8A 5EF8A 2EF4A 3E9BA 4QA4A 3SL0A 3GN0A 4HZEA 4ZUNA 4GWDA 1TBJA 3PZLA 3NIQA 4QA0A 3Q9CA 4ZUOA 5THUA 1GQ6A 4Q3TA 5DC5A 4IXUA 1C3RA 1WVAA 5FCWA 4BZ6A 1WOGA 2GH6A 3DJ8A 5DC7A 5EFGA 2VQMA 5G1CA 4IE1A 4Q42A 4QA3A 1HQ5A 2V5WA 4Q3RC 5EEKA 3E6VA 4RN0A 4BZ9A 3MFWA 1T5FA 1TBHA 3MFVA 3Q9FA 3NIPA 5G3WA 1C3PA 3MENA 1P8RA 1T64A 4BZ5A 3M1RA 4MYFA 4Q40A 4GSZA 4RHQA 5EFHA 5IX0A 3SFHA 4Q41A 5G10A 4ZUPA 1T67A 5FUEA 3E6KA 5G0GA 5ICNB 3ZNSA 4RHJA 5G0YA 1T4PA 1T4RA 5D1BA 2PHAA 4ZURA 2VCGA 3F07A 4IU1A 5EFBD 4IU4A 4MYKA 5THTA 2VQQA 1P8MA 4BZ8A 2VQWG 3EZTA 4GWCA 3F80A 3C10A 4LXZA 4CBYA 3MZ7A 3C0YA 2VQJA 5THSA 4A69A 1XFKA 5G13A 2A0MA 2EF5A 2PHOA 1P8OA 5EFJD 3MZ6A 1P8NA 5EFKB 2V5XA 1R1OA 1T5GA 4IE3A 4MXRA 5DC8A 2PLLA 5D1CA
chains in the Genus database with same CATH topology
4IE2A 3E8ZA 1ZPEA 1T4TA 2ZAVA 2RLAA 4GSVA 4RHKA 3CEVA 1P8PA 4FCIA 4RLAA 4CEVA 3KV2A 1P8QA 4HWWA 3MJLA 1T4SA 3THHA 1D3VA 5HJAA 1HQGA 1P8SA 1HQHA 3SJTA 3GMZA 5RLAA 3TH7A 1WOIA 3E8QA 1TBLA 3NIOA 4GSMA 1GQ7A 4IU0A 3SKKA 1RLAA 4RHLA 1HQFA 4Q3PA 4HXQA 1WVBA 4IU5A 5HJ9A 4Q3QA 4I06A 3LHLA 4RHIA 5CEVA 4Q3RA 1ZPGA 1CEVA 4Q3UA 4FCKA 4ITYA 2EIVA 4MYNA 1WOHA 3LP4A 3THJA 3TF3A 3SL1A 3RLAA 4Q3SA 4MYLA 1TA1A 3MMRA 4IXVA 2AEBA 3LP7A 2CEVA 1HQXA 4G3HA 1PQ3A 4Q3VA 4RHMA 3THEA 2EF4A 3E9BA 3SL0A 3GN0A 4HZEA 4GWDA 1TBJA 3PZLA 3NIQA 1GQ6A 4Q3TA 4IXUA 1WVAA 1WOGA 3DJ8A 4IE1A 4Q42A 1HQ5A 4Q3RC 3E6VA 3MFWA 1T5FA 1TBHA 3MFVA 3NIPA 1P8RA 3M1RA 4MYFA 4Q40A 4GSZA 4RHQA 4Q41A 3E6KA 4RHJA 1T4PA 1T4RA 2PHAA 4IU1A 4IU4A 4MYKA 1P8MA 4GWCA 3F80A 1XFKA 2A0MA 2EF5A 2PHOA 1P8OA 1P8NA 1R1OA 1T5GA 4IE3A 4MXRA 2PLLA 4DZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IE2 A;  3E8Z A;  1ZPE A;  1T4T A;  2ZAV A;  2RLA A;  4GSV A;  4RHK A;  3CEV A;  1P8P A;  4FCI A;  4RLA A;  4CEV A;  3KV2 A;  1P8Q A;  4HWW A;  3MJL A;  1T4S A;  3THH A;  1D3V A;  5HJA A;  1HQG A;  1P8S A;  1HQH A;  3SJT A;  3GMZ A;  5RLA A;  3TH7 A;  1WOI A;  3E8Q A;  1TBL A;  3NIO A;  4GSM A;  1GQ7 A;  4IU0 A;  3SKK A;  1RLA A;  4RHL A;  1HQF A;  4Q3P A;  4HXQ A;  1WVB A;  4IU5 A;  5HJ9 A;  4Q3Q A;  4I06 A;  3LHL A;  4RHI A;  5CEV A;  4Q3R A;  1ZPG A;  1CEV A;  4Q3U A;  4FCK A;  4ITY A;  2EIV A;  4MYN A;  1WOH A;  3LP4 A;  3THJ A;  3TF3 A;  3SL1 A;  3RLA A;  4Q3S A;  4MYL A;  1TA1 A;  3MMR A;  4IXV A;  2AEB A;  3LP7 A;  2CEV A;  1HQX A;  4G3H A;  1PQ3 A;  4Q3V A;  4RHM A;  3THE A;  2EF4 A;  3E9B A;  3SL0 A;  3GN0 A;  4HZE A;  4GWD A;  1TBJ A;  3PZL A;  3NIQ A;  1GQ6 A;  4Q3T A;  4IXU A;  1WVA A;  1WOG A;  3DJ8 A;  4IE1 A;  4Q42 A;  1HQ5 A;  4Q3R C;  3E6V A;  3MFW A;  1T5F A;  1TBH A;  3MFV A;  3NIP A;  1P8R A;  3M1R A;  4MYF A;  4Q40 A;  4GSZ A;  4RHQ A;  4Q41 A;  3E6K A;  4RHJ A;  1T4P A;  1T4R A;  2PHA A;  4IU1 A;  4IU4 A;  4MYK A;  1P8M A;  4GWC A;  3F80 A;  1XFK A;  2A0M A;  2EF5 A;  2PHO A;  1P8O A;  1P8N A;  1R1O A;  1T5G A;  4IE3 A;  4MXR A;  2PLL A;  4DZ4 A; 
#chains in the Genus database with same CATH topology
 4BZ7 A;  4IE2 A;  4DZ4 A;  3E8Z A;  1ZPE A;  1T4T A;  2ZAV A;  5G12 A;  2RLA A;  4GSV A;  3F0R A;  5EF7 A;  2VQO A;  3MZ4 A;  4RHK A;  5EFN A;  5D1D A;  5G1B A;  3CEV A;  1P8P A;  4FCI A;  4RLA A;  1W22 A;  4BKX B;  3KV2 A;  4CEV A;  5EEF A;  1P8Q A;  4HWW A;  3MJL A;  1T4S A;  3THH A;  1D3V A;  4QA7 A;  5HJA A;  5G17 A;  3EZP A;  3Q9E A;  3RQD A;  4CBT A;  5G0H A;  1HQG A;  1P8S A;  4LY1 A;  1HQH A;  1T69 A;  3SJT A;  3GMZ A;  5LI3 A;  3THE A;  5RLA A;  3TH7 A;  4QA2 A;  1ZZ1 A;  5A2S A;  1WOI A;  3E8Q A;  1TBL A;  3NIO A;  5G11 A;  4ZUQ A;  4GSM A;  1GQ7 A;  4IU0 A;  3SKK A;  1RLA A;  4RHL A;  1HQF A;  5G0J A;  4Q3P A;  4HXQ A;  1WVB A;  4IU5 A;  5HJ9 A;  4Q3Q A;  3F06 A;  5THV A;  4I06 A;  3LHL A;  5EEM A;  4RHI A;  3ZNR A;  1VKG A;  5CEV A;  3MZ3 A;  4Q3R A;  4RN2 A;  1ZPG A;  5JI5 A;  3SFF A;  1ZZ0 A;  1ZZ3 A;  1CEV A;  5EEN A;  3EWF A;  4Q3U A;  4FCK A;  4ITY A;  2EIV A;  3MAX A;  4MYN A;  4QA5 A;  1WOH A;  4QA1 A;  4ZUM A;  5BWZ A;  4CQF A;  3Q9B A;  3LP4 A;  4RN1 A;  3THJ A;  5G0X A;  5DC6 A;  3TF3 A;  4QA6 A;  3C0Z A;  5EEI A;  3SL1 A;  3RLA A;  2VQV A;  4Q3S A;  5G1A A;  5IWG A;  4MYL A;  1C3S A;  1TA1 A;  3MMR A;  4IXV A;  2AEB A;  3LP7 A;  2CEV A;  1HQX A;  4G3H A;  1PQ3 A;  4Q3V A;  4RHM A;  5G0I A;  3EW8 A;  5EF8 A;  2EF4 A;  3E9B A;  4QA4 A;  3SL0 A;  3GN0 A;  4HZE A;  4ZUN A;  4GWD A;  1TBJ A;  3PZL A;  3NIQ A;  4QA0 A;  3Q9C A;  4ZUO A;  5THU A;  1GQ6 A;  4Q3T A;  5DC5 A;  4IXU A;  1C3R A;  1WVA A;  5FCW A;  4BZ6 A;  1WOG A;  2GH6 A;  3DJ8 A;  5DC7 A;  5EFG A;  2VQM A;  5G1C A;  4IE1 A;  4Q42 A;  4QA3 A;  1HQ5 A;  2V5W A;  4Q3R C;  5EEK A;  3E6V A;  4RN0 A;  4BZ9 A;  3MFW A;  1T5F A;  1TBH A;  3MFV A;  3Q9F A;  3NIP A;  5G3W A;  1C3P A;  3MEN A;  1P8R A;  1T64 A;  4BZ5 A;  3M1R A;  4MYF A;  4Q40 A;  4GSZ A;  4RHQ A;  5EFH A;  5IX0 A;  3SFH A;  4Q41 A;  5G10 A;  4ZUP A;  1T67 A;  5FUE A;  3E6K A;  5G0G A;  5ICN B;  3ZNS A;  4RHJ A;  5G0Y A;  1T4P A;  1T4R A;  5D1B A;  2PHA A;  4ZUR A;  2VCG A;  3F07 A;  4IU1 A;  5EFB D;  4IU4 A;  4MYK A;  5THT A;  2VQQ A;  1P8M A;  4BZ8 A;  2VQW G;  3EZT A;  4GWC A;  3F80 A;  3C10 A;  4LXZ A;  4CBY A;  3MZ7 A;  3C0Y A;  2VQJ A;  5THS A;  4A69 A;  1XFK A;  5G13 A;  2A0M A;  2EF5 A;  2PHO A;  1P8O A;  5EFJ D;  3MZ6 A;  1P8N A;  5EFK B;  2V5X A;  1R1O A;  1T5G A;  4IE3 A;  4MXR A;  5DC8 A;  2PLL A;  5D1C A; 
#chains in the Genus database with same CATH homology
 4IE2 A;  3E8Z A;  1ZPE A;  1T4T A;  2ZAV A;  2RLA A;  4GSV A;  4RHK A;  3CEV A;  1P8P A;  4FCI A;  4RLA A;  4CEV A;  3KV2 A;  1P8Q A;  4HWW A;  3MJL A;  1T4S A;  3THH A;  1D3V A;  5HJA A;  1HQG A;  1P8S A;  1HQH A;  3SJT A;  3GMZ A;  5RLA A;  3TH7 A;  1WOI A;  3E8Q A;  1TBL A;  3NIO A;  4GSM A;  1GQ7 A;  4IU0 A;  3SKK A;  1RLA A;  4RHL A;  1HQF A;  4Q3P A;  4HXQ A;  1WVB A;  4IU5 A;  5HJ9 A;  4Q3Q A;  4I06 A;  3LHL A;  4RHI A;  5CEV A;  4Q3R A;  1ZPG A;  1CEV A;  4Q3U A;  4FCK A;  4ITY A;  2EIV A;  4MYN A;  1WOH A;  3LP4 A;  3THJ A;  3TF3 A;  3SL1 A;  3RLA A;  4Q3S A;  4MYL A;  1TA1 A;  3MMR A;  4IXV A;  2AEB A;  3LP7 A;  2CEV A;  1HQX A;  4G3H A;  1PQ3 A;  4Q3V A;  4RHM A;  3THE A;  2EF4 A;  3E9B A;  3SL0 A;  3GN0 A;  4HZE A;  4GWD A;  1TBJ A;  3PZL A;  3NIQ A;  1GQ6 A;  4Q3T A;  4IXU A;  1WVA A;  1WOG A;  3DJ8 A;  4IE1 A;  4Q42 A;  1HQ5 A;  4Q3R C;  3E6V A;  3MFW A;  1T5F A;  1TBH A;  3MFV A;  3NIP A;  1P8R A;  3M1R A;  4MYF A;  4Q40 A;  4GSZ A;  4RHQ A;  4Q41 A;  3E6K A;  4RHJ A;  1T4P A;  1T4R A;  2PHA A;  4IU1 A;  4IU4 A;  4MYK A;  1P8M A;  4GWC A;  3F80 A;  1XFK A;  2A0M A;  2EF5 A;  2PHO A;  1P8O A;  1P8N A;  1R1O A;  1T5G A;  4IE3 A;  4MXR A;  2PLL A;  4DZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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