3SL0A

Crystal structure of p. falciparum arginase complexed with 2-amino-6-borono-2-(difluoromethyl)hexanoic acid
Total Genus 118
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
118
sequence length
390
structure length
308
Chain Sequence
b'KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSENLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Arginase
publication title Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
pubmed doi rcsb
source organism Plasmodium falciparum
molecule tags Hydrolase/hydrolase inhibitor
total genus 118
structure length 308
sequence length 390
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2011-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3sl0A00
3NIOA 4RHIA 1ZPGA 1P8PA 2PLLA 1R1OA 3CEVA 1P8MA 3PZLA 1HQFA 4IU1A 1TBLA 1ZPEA 4GWDA 4IE1A 4Q3QA 4RHMA 4Q3RC 3M1RA 3THHA 1HQGA 3SJTA 1RLAA 1D3VA 4IE2A 4Q3UA 4FCKA 4HXQA 4Q40A 1P8OA 4IE3A 3TH7A 4CEVA 4ITYA 3MJLA 5HJAA 4Q3PA 4RHKA 4IXVA 4G3HA 4Q41A 2RLAA 3NIPA 4DZ4A 1T5GA 3MFWA 3GN0A 3THJA 1T4RA 3E6KA 1TA1A 1XFKA 4IU4A 1GQ6A 1HQ5A 4RHJA 3DJ8A 2A0MA 2PHOA 1P8RA 4Q3SA 1GQ7A 4I06A 3THEA 4Q3TA 1WOHA 3SKKA 3E8QA 3TF3A 4FCIA 4MXRA 3E9BA 4IU5A 4GSVA 1HQHA 1WOGA 2AEBA 3MMRA 1T4TA 3SL0A 4RLAA 3E6VA 4Q3RA 1TBHA 1TBJA 2EF4A 3KV2A 4MYNA 2CEVA 4MYLA 1WVAA 1P8NA 1P8QA 1T4SA 4IU0A 1WVBA 5CEVA 1P8SA 1T4PA 2ZAVA 3NIQA 3LP4A 2PHAA 3LP7A 4IXUA 4MYKA 4RHLA 4GWCA 1T5FA 3SL1A 1PQ3A 3E8ZA 1WOIA 4RHQA 3GMZA 4MYFA 2EIVA 1CEVA 3MFVA 3F80A 2EF5A 5RLAA 3RLAA 4HZEA 4GSMA 4Q42A 4GSZA 4HWWA 5HJ9A 3LHLA 4Q3VA 1HQXA
chains in the Genus database with same CATH superfamily
3NIOA 4BZ5A 4QA6A 4RHIA 1ZPGA 5THVA 1P8PA 2PLLA 5EF8A 3ZNRA 1R1OA 3Q9FA 2VQOA 5D1BA 5D1CA 3MAXA 3CEVA 5G1BA 1P8MA 3PZLA 1HQFA 4BZ9A 1C3PA 4IU1A 1TBLA 1T69A 1C3RA 1ZPEA 4GWDA 3EWFA 4QA3A 4IE1A 4Q3QA 4QA4A 3C0YA 4RHMA 2V5WA 4Q3RC 4RN2A 3M1RA 3THHA 1HQGA 5EFJD 4BZ6A 3SJTA 5D1DA 1RLAA 1D3VA 1ZZ0A 3F07A 5DC6A 5EFGA 3Q9BA 4IE2A 5G0IA 4Q3UA 4QA7A 3MENA 4FCKA 3MZ6A 4HXQA 5G0GA 4Q40A 1P8OA 4ZUMA 4IE3A 1ZZ1A 2VQVA 3TH7A 4CEVA 4ZUOA 4ITYA 4BKXB 3MJLA 5HJAA 4Q3PA 4RHKA 3RQDA 5EEIA 3Q9CA 5BWZA 4IXVA 4G3HA 4QA0A 5EEMA 5IWGA 4Q41A 2RLAA 3NIPA 4DZ4A 1T5GA 4QA5A 3MFWA 3GN0A 3THJA 3SFFA 5EFBD 3C10A 1T4RA 3E6KA 5EFHA 1TA1A 1XFKA 5EEFA 4LY1A 4ZUQA 4IU4A 1GQ6A 5G17A 1HQ5A 3SFHA 5G3WA 5THSA 4Q3VA 3ZNSA 4A69A 3F0RA 4CBTA 4RHJA 4QA2A 3DJ8A 3EZTA 2A0MA 2PHOA 1P8RA 5EF7A 5G0YA 5ICNB 5G11A 4BZ7A 4Q3SA 1GQ7A 4I06A 5EFNA 4ZURA 3THEA 5THTA 4Q3TA 3MZ7A 1WOHA 3SKKA 3E8QA 3TF3A 2VQQA 4FCIA 4MXRA 3E9BA 4IU5A 4GSVA 1HQHA 1W22A 5G0HA 1WOGA 5EFKB 2AEBA 3MMRA 1T4TA 3SL0A 3EW8A 4RLAA 5G10A 3MZ3A 3E6VA 4Q3RA 5G13A 1C3SA 5A2SA 1TBHA 1TBJA 2EF4A 2VCGA 3KV2A 4MYNA 2CEVA 5G1AA 4BZ8A 5THUA 4MYLA 1WVAA 4CQFA 1P8NA 1P8QA 1T4SA 5FCWA 4IU0A 2V5XA 4RN0A 3EZPA 1WVBA 5EEKA 2GH6A 1T4PA 2ZAVA 1P8SA 3NIQA 4CBYA 5CEVA 3LP4A 2PHAA 3LP7A 5IX0A 4IXUA 4MYKA 4RHLA 4GWCA 1T5FA 3SL1A 1PQ3A 3E8ZA 1WOIA 1T64A 4RHQA 2VQJA 4QA1A 5DC5A 3GMZA 3MZ4A 4MYFA 5G12A 2EIVA 1CEVA 3F06A 3MFVA 2VQWG 5DC8A 3F80A 3C0ZA 2EF5A 5G0XA 5RLAA 3RLAA 5JI5A 5EENA 4HZEA 5G0JA 4GSMA 4Q42A 1T67A 1ZZ3A 2VQMA 5FUEA 4ZUPA 4GSZA 4HWWA 3Q9EA 4RN1A 5HJ9A 5DC7A 4ZUNA 5G1CA 5LI3A 4LXZA 3LHLA 1VKGA 1HQXA
chains in the Genus database with same CATH topology
3NIOA 4RHIA 1ZPGA 1P8PA 2PLLA 1R1OA 3CEVA 1P8MA 3PZLA 1HQFA 4IU1A 1TBLA 1ZPEA 4GWDA 4IE1A 4Q3QA 4RHMA 4Q3RC 3M1RA 3THHA 1HQGA 3SJTA 1RLAA 1D3VA 4IE2A 4Q3UA 4FCKA 4HXQA 4Q40A 1P8OA 4IE3A 3TH7A 4CEVA 4ITYA 3MJLA 5HJAA 4Q3PA 4RHKA 4IXVA 4G3HA 4Q41A 2RLAA 3NIPA 4DZ4A 1T5GA 3MFWA 3GN0A 3THJA 1T4RA 3E6KA 1TA1A 1XFKA 4IU4A 1GQ6A 1HQ5A 4RHJA 3DJ8A 2A0MA 2PHOA 1P8RA 4Q3SA 1GQ7A 4I06A 3THEA 4Q3TA 1WOHA 3SKKA 3E8QA 3TF3A 4FCIA 4MXRA 3E9BA 4IU5A 4GSVA 1HQHA 1WOGA 2AEBA 3MMRA 1T4TA 3SL0A 4RLAA 3E6VA 4Q3RA 1TBHA 1TBJA 2EF4A 3KV2A 4MYNA 2CEVA 4MYLA 1WVAA 1P8NA 1P8QA 1T4SA 4IU0A 1WVBA 5CEVA 1P8SA 1T4PA 2ZAVA 3NIQA 3LP4A 2PHAA 3LP7A 4IXUA 4MYKA 4RHLA 4GWCA 1T5FA 3SL1A 1PQ3A 3E8ZA 1WOIA 4RHQA 3GMZA 4MYFA 2EIVA 1CEVA 3MFVA 3F80A 2EF5A 5RLAA 3RLAA 4HZEA 4GSMA 4Q42A 4GSZA 4HWWA 5HJ9A 3LHLA 4Q3VA 1HQXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NIO A;  4RHI A;  1ZPG A;  1P8P A;  2PLL A;  1R1O A;  3CEV A;  1P8M A;  3PZL A;  1HQF A;  4IU1 A;  1TBL A;  1ZPE A;  4GWD A;  4IE1 A;  4Q3Q A;  4RHM A;  4Q3R C;  3M1R A;  3THH A;  1HQG A;  3SJT A;  1RLA A;  1D3V A;  4IE2 A;  4Q3U A;  4FCK A;  4HXQ A;  4Q40 A;  1P8O A;  4IE3 A;  3TH7 A;  4CEV A;  4ITY A;  3MJL A;  5HJA A;  4Q3P A;  4RHK A;  4IXV A;  4G3H A;  4Q41 A;  2RLA A;  3NIP A;  4DZ4 A;  1T5G A;  3MFW A;  3GN0 A;  3THJ A;  1T4R A;  3E6K A;  1TA1 A;  1XFK A;  4IU4 A;  1GQ6 A;  1HQ5 A;  4RHJ A;  3DJ8 A;  2A0M A;  2PHO A;  1P8R A;  4Q3S A;  1GQ7 A;  4I06 A;  3THE A;  4Q3T A;  1WOH A;  3SKK A;  3E8Q A;  3TF3 A;  4FCI A;  4MXR A;  3E9B A;  4IU5 A;  4GSV A;  1HQH A;  1WOG A;  2AEB A;  3MMR A;  1T4T A;  3SL0 A;  4RLA A;  3E6V A;  4Q3R A;  1TBH A;  1TBJ A;  2EF4 A;  3KV2 A;  4MYN A;  2CEV A;  4MYL A;  1WVA A;  1P8N A;  1P8Q A;  1T4S A;  4IU0 A;  1WVB A;  5CEV A;  1P8S A;  1T4P A;  2ZAV A;  3NIQ A;  3LP4 A;  2PHA A;  3LP7 A;  4IXU A;  4MYK A;  4RHL A;  4GWC A;  1T5F A;  3SL1 A;  1PQ3 A;  3E8Z A;  1WOI A;  4RHQ A;  3GMZ A;  4MYF A;  2EIV A;  1CEV A;  3MFV A;  3F80 A;  2EF5 A;  5RLA A;  3RLA A;  4HZE A;  4GSM A;  4Q42 A;  4GSZ A;  4HWW A;  5HJ9 A;  3LHL A;  4Q3V A;  1HQX A; 
#chains in the Genus database with same CATH topology
 3NIO A;  4BZ5 A;  4QA6 A;  4RHI A;  1ZPG A;  5THV A;  1P8P A;  2PLL A;  5EF8 A;  3ZNR A;  1R1O A;  3Q9F A;  2VQO A;  5D1B A;  5D1C A;  3MAX A;  3CEV A;  5G1B A;  1P8M A;  3PZL A;  1HQF A;  4BZ9 A;  1C3P A;  4IU1 A;  1TBL A;  1T69 A;  1C3R A;  1ZPE A;  4GWD A;  3EWF A;  4QA3 A;  4IE1 A;  4Q3Q A;  4QA4 A;  3C0Y A;  4RHM A;  2V5W A;  4Q3R C;  4RN2 A;  3M1R A;  3THH A;  1HQG A;  5EFJ D;  4BZ6 A;  3SJT A;  5D1D A;  1RLA A;  1D3V A;  1ZZ0 A;  3F07 A;  5DC6 A;  5EFG A;  3Q9B A;  4IE2 A;  5G0I A;  4Q3U A;  4QA7 A;  3MEN A;  4FCK A;  3MZ6 A;  4HXQ A;  5G0G A;  4Q40 A;  1P8O A;  4ZUM A;  4IE3 A;  1ZZ1 A;  2VQV A;  3TH7 A;  4CEV A;  4ZUO A;  4ITY A;  4BKX B;  3MJL A;  5HJA A;  4Q3P A;  4RHK A;  3RQD A;  5EEI A;  3Q9C A;  5BWZ A;  4IXV A;  4G3H A;  4QA0 A;  5EEM A;  5IWG A;  4Q41 A;  2RLA A;  3NIP A;  4DZ4 A;  1T5G A;  4QA5 A;  3MFW A;  3GN0 A;  3THJ A;  3SFF A;  5EFB D;  3C10 A;  1T4R A;  3E6K A;  5EFH A;  1TA1 A;  1XFK A;  5EEF A;  4LY1 A;  4ZUQ A;  4IU4 A;  1GQ6 A;  5G17 A;  1HQ5 A;  3SFH A;  5G3W A;  5THS A;  4Q3V A;  3ZNS A;  4A69 A;  3F0R A;  4CBT A;  4RHJ A;  4QA2 A;  3DJ8 A;  3EZT A;  2A0M A;  2PHO A;  1P8R A;  5EF7 A;  5G0Y A;  5ICN B;  5G11 A;  4BZ7 A;  4Q3S A;  1GQ7 A;  4I06 A;  5EFN A;  4ZUR A;  3THE A;  5THT A;  4Q3T A;  3MZ7 A;  1WOH A;  3SKK A;  3E8Q A;  3TF3 A;  2VQQ A;  4FCI A;  4MXR A;  3E9B A;  4IU5 A;  4GSV A;  1HQH A;  1W22 A;  5G0H A;  1WOG A;  5EFK B;  2AEB A;  3MMR A;  1T4T A;  3SL0 A;  3EW8 A;  4RLA A;  5G10 A;  3MZ3 A;  3E6V A;  4Q3R A;  5G13 A;  1C3S A;  5A2S A;  1TBH A;  1TBJ A;  2EF4 A;  2VCG A;  3KV2 A;  4MYN A;  2CEV A;  5G1A A;  4BZ8 A;  5THU A;  4MYL A;  1WVA A;  4CQF A;  1P8N A;  1P8Q A;  1T4S A;  5FCW A;  4IU0 A;  2V5X A;  4RN0 A;  3EZP A;  1WVB A;  5EEK A;  2GH6 A;  1T4P A;  2ZAV A;  1P8S A;  3NIQ A;  4CBY A;  5CEV A;  3LP4 A;  2PHA A;  3LP7 A;  5IX0 A;  4IXU A;  4MYK A;  4RHL A;  4GWC A;  1T5F A;  3SL1 A;  1PQ3 A;  3E8Z A;  1WOI A;  1T64 A;  4RHQ A;  2VQJ A;  4QA1 A;  5DC5 A;  3GMZ A;  3MZ4 A;  4MYF A;  5G12 A;  2EIV A;  1CEV A;  3F06 A;  3MFV A;  2VQW G;  5DC8 A;  3F80 A;  3C0Z A;  2EF5 A;  5G0X A;  5RLA A;  3RLA A;  5JI5 A;  5EEN A;  4HZE A;  5G0J A;  4GSM A;  4Q42 A;  1T67 A;  1ZZ3 A;  2VQM A;  5FUE A;  4ZUP A;  4GSZ A;  4HWW A;  3Q9E A;  4RN1 A;  5HJ9 A;  5DC7 A;  4ZUN A;  5G1C A;  5LI3 A;  4LXZ A;  3LHL A;  1VKG A;  1HQX A; 
#chains in the Genus database with same CATH homology
 3NIO A;  4RHI A;  1ZPG A;  1P8P A;  2PLL A;  1R1O A;  3CEV A;  1P8M A;  3PZL A;  1HQF A;  4IU1 A;  1TBL A;  1ZPE A;  4GWD A;  4IE1 A;  4Q3Q A;  4RHM A;  4Q3R C;  3M1R A;  3THH A;  1HQG A;  3SJT A;  1RLA A;  1D3V A;  4IE2 A;  4Q3U A;  4FCK A;  4HXQ A;  4Q40 A;  1P8O A;  4IE3 A;  3TH7 A;  4CEV A;  4ITY A;  3MJL A;  5HJA A;  4Q3P A;  4RHK A;  4IXV A;  4G3H A;  4Q41 A;  2RLA A;  3NIP A;  4DZ4 A;  1T5G A;  3MFW A;  3GN0 A;  3THJ A;  1T4R A;  3E6K A;  1TA1 A;  1XFK A;  4IU4 A;  1GQ6 A;  1HQ5 A;  4RHJ A;  3DJ8 A;  2A0M A;  2PHO A;  1P8R A;  4Q3S A;  1GQ7 A;  4I06 A;  3THE A;  4Q3T A;  1WOH A;  3SKK A;  3E8Q A;  3TF3 A;  4FCI A;  4MXR A;  3E9B A;  4IU5 A;  4GSV A;  1HQH A;  1WOG A;  2AEB A;  3MMR A;  1T4T A;  3SL0 A;  4RLA A;  3E6V A;  4Q3R A;  1TBH A;  1TBJ A;  2EF4 A;  3KV2 A;  4MYN A;  2CEV A;  4MYL A;  1WVA A;  1P8N A;  1P8Q A;  1T4S A;  4IU0 A;  1WVB A;  5CEV A;  1P8S A;  1T4P A;  2ZAV A;  3NIQ A;  3LP4 A;  2PHA A;  3LP7 A;  4IXU A;  4MYK A;  4RHL A;  4GWC A;  1T5F A;  3SL1 A;  1PQ3 A;  3E8Z A;  1WOI A;  4RHQ A;  3GMZ A;  4MYF A;  2EIV A;  1CEV A;  3MFV A;  3F80 A;  2EF5 A;  5RLA A;  3RLA A;  4HZE A;  4GSM A;  4Q42 A;  4GSZ A;  4HWW A;  5HJ9 A;  3LHL A;  4Q3V A;  1HQX A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...