3THEA

Crystal structure of co2+2-hai (ph 8.5)
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of complexes with cobalt-reconstituted human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 117
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2011-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3theA00
3CEVA 1T4RA 1TA1A 3PZLA 3E6KA 4MYLA 1WVBA 2PLLA 1TBJA 1HQFA 4HXQA 3SL0A 4Q41A 3NIQA 2RLAA 1HQHA 4MYFA 1R1OA 4I06A 4RHIA 3TH7A 1P8MA 1WOIA 3KV2A 3RLAA 4GWDA 3E8QA 2CEVA 1T4SA 4Q3VA 1WOHA 3LP4A 1GQ7A 3TF3A 4Q3PA 4Q3RA 4HZEA 4GSZA 4CEVA 4Q3TA 4RHMA 4IXUA 3SKKA 3THJA 1GQ6A 3F80A 2ZAVA 3M1RA 1RLAA 5CEVA 1XFKA 1D3VA 2EF5A 4GSMA 1WVAA 4IU0A 3LP7A 4RLAA 1CEVA 4Q3RC 4FCKA 4DZ4A 4GSVA 1P8NA 1P8OA 1T4PA 4MYNA 3MFVA 3SJTA 1P8SA 4Q3UA 1WOGA 5HJAA 1HQGA 2AEBA 4IE2A 1TBLA 4ITYA 1ZPEA 3THEA 4GWCA 1TBHA 1HQXA 4HWWA 4IU1A 4Q40A 3NIPA 1ZPGA 3NIOA 4MYKA 5HJ9A 4Q42A 1P8PA 3GMZA 3LHLA 3MMRA 2EIVA 1T5FA 3MJLA 3E9BA 4RHQA 3E6VA 2PHOA 3MFWA 4IU4A 2PHAA 4Q3SA 3SL1A 4IE1A 4G3HA 4RHJA 1T5GA 4IE3A 2A0MA 1P8QA 4Q3QA 4FCIA 1HQ5A 4MXRA 4RHKA 4RHLA 4IXVA 2EF4A 4IU5A 3E8ZA 3THHA 5RLAA 1P8RA 1T4TA 1PQ3A 3DJ8A 3GN0A
chains in the Genus database with same CATH superfamily
3CEVA 1T4RA 5D1CA 3Q9CA 4QA7A 4QA3A 5EEIA 1T64A 4ZUPA 1TA1A 3Q9FA 5G1AA 4LXZA 2VQVA 3PZLA 4MYLA 5EENA 3F0RA 1WVBA 2PLLA 5G1CA 1TBJA 1HQFA 5A2SA 4HXQA 3SL0A 4Q41A 4CBTA 4CQFA 3NIQA 2RLAA 1HQHA 3EW8A 3MZ4A 4BZ5A 4ZUQA 4MYFA 4BKXB 5JI5A 3MENA 1R1OA 5G17A 3ZNRA 2V5XA 4I06A 4RHIA 3TH7A 1P8MA 1WOIA 3KV2A 3RLAA 5G13A 4GWDA 5THVA 3MZ3A 5D1DA 5G3WA 3Q9BA 3E8QA 3MAXA 3MZ7A 2CEVA 1T4SA 3GN0A 4QA2A 3EWFA 4Q3VA 5DC5A 1WOHA 3LP4A 1GQ7A 5G12A 5G1BA 3RQDA 3TF3A 4Q3PA 4Q3RA 5EF8A 5G0HA 4HZEA 4GSZA 4CEVA 5ICNB 4Q3TA 4RHMA 4ZURA 4ZUNA 2VQQA 3EZTA 2VQWG 4IXUA 3SKKA 5LI3A 3THJA 1GQ6A 1ZZ0A 4BZ6A 4QA1A 3F80A 2ZAVA 3F06A 3M1RA 5IWGA 5EEMA 4RN2A 5EFBD 4A69A 1RLAA 5CEVA 5EFGA 1XFKA 3MZ6A 1D3VA 2EF5A 4GSMA 1WVAA 5EFJD 3F07A 5THSA 4IU0A 3LP7A 3C0YA 4RLAA 1CEVA 2VQMA 1C3PA 4Q3RC 4ZUMA 4FCKA 5G11A 1C3SA 4DZ4A 4GSVA 1P8NA 1P8OA 1T4PA 1W22A 1ZZ1A 2VQJA 4MYNA 2VQOA 5IX0A 3C10A 5G0IA 3ZNSA 3MFVA 3SJTA 1P8SA 5G0JA 4Q3UA 1WOGA 5HJAA 1HQGA 4RN0A 2AEBA 5D1BA 4IE2A 1TBLA 5G0GA 5EFHA 4ITYA 1ZPEA 3THEA 1C3RA 4GWCA 5DC8A 2VCGA 5EFNA 1TBHA 1HQXA 4HWWA 4IU1A 4Q40A 3NIPA 1ZPGA 3NIOA 5EEFA 4LY1A 4MYKA 1T67A 4Q42A 5HJ9A 1P8PA 2GH6A 3GMZA 3LHLA 5THTA 4CBYA 3MMRA 2EIVA 1T5FA 5FUEA 5THUA 3MJLA 3E9BA 3Q9EA 4RHQA 4RN1A 3E6VA 2PHOA 3MFWA 4IU4A 2PHAA 4Q3SA 3SL1A 4IE1A 5G0YA 5DC6A 4G3HA 4RHJA 5EF7A 1T5GA 4IE3A 3SFHA 4BZ8A 5BWZA 2V5WA 3EZPA 2A0MA 1P8QA 4Q3QA 4QA4A 4FCIA 5EFKB 3SFFA 4BZ9A 1T69A 1HQ5A 4MXRA 4RHKA 5FCWA 4ZUOA 4RHLA 4QA0A 4QA5A 4IXVA 2EF4A 4IU5A 4QA6A 1VKGA 3E8ZA 1ZZ3A 5RLAA 1P8RA 1T4TA 3THHA 5DC7A 5G0XA 4BZ7A 5G10A 3C0ZA 1PQ3A 5EEKA 3DJ8A 3E6KA
chains in the Genus database with same CATH topology
3CEVA 1T4RA 1TA1A 3PZLA 3E6KA 4MYLA 1WVBA 2PLLA 1TBJA 1HQFA 4HXQA 3SL0A 4Q41A 3NIQA 2RLAA 1HQHA 4MYFA 1R1OA 4I06A 4RHIA 3TH7A 1P8MA 1WOIA 3KV2A 3RLAA 4GWDA 3E8QA 2CEVA 1T4SA 4Q3VA 1WOHA 3LP4A 1GQ7A 3TF3A 4Q3PA 4Q3RA 4HZEA 4GSZA 4CEVA 4Q3TA 4RHMA 4IXUA 3SKKA 3THJA 1GQ6A 3F80A 2ZAVA 3M1RA 1RLAA 5CEVA 1XFKA 1D3VA 2EF5A 4GSMA 1WVAA 4IU0A 3LP7A 4RLAA 1CEVA 4Q3RC 4FCKA 4DZ4A 4GSVA 1P8NA 1P8OA 1T4PA 4MYNA 3MFVA 3SJTA 1P8SA 4Q3UA 1WOGA 5HJAA 1HQGA 2AEBA 4IE2A 1TBLA 4ITYA 1ZPEA 3THEA 4GWCA 1TBHA 1HQXA 4HWWA 4IU1A 4Q40A 3NIPA 1ZPGA 3NIOA 4MYKA 5HJ9A 4Q42A 1P8PA 3GMZA 3LHLA 3MMRA 2EIVA 1T5FA 3MJLA 3E9BA 4RHQA 3E6VA 2PHOA 3MFWA 4IU4A 2PHAA 4Q3SA 3SL1A 4IE1A 4G3HA 4RHJA 1T5GA 4IE3A 2A0MA 1P8QA 4Q3QA 4FCIA 1HQ5A 4MXRA 4RHKA 4RHLA 4IXVA 2EF4A 4IU5A 3E8ZA 3THHA 5RLAA 1P8RA 1T4TA 1PQ3A 3DJ8A 3GN0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CEV A;  1T4R A;  1TA1 A;  3PZL A;  3E6K A;  4MYL A;  1WVB A;  2PLL A;  1TBJ A;  1HQF A;  4HXQ A;  3SL0 A;  4Q41 A;  3NIQ A;  2RLA A;  1HQH A;  4MYF A;  1R1O A;  4I06 A;  4RHI A;  3TH7 A;  1P8M A;  1WOI A;  3KV2 A;  3RLA A;  4GWD A;  3E8Q A;  2CEV A;  1T4S A;  4Q3V A;  1WOH A;  3LP4 A;  1GQ7 A;  3TF3 A;  4Q3P A;  4Q3R A;  4HZE A;  4GSZ A;  4CEV A;  4Q3T A;  4RHM A;  4IXU A;  3SKK A;  3THJ A;  1GQ6 A;  3F80 A;  2ZAV A;  3M1R A;  1RLA A;  5CEV A;  1XFK A;  1D3V A;  2EF5 A;  4GSM A;  1WVA A;  4IU0 A;  3LP7 A;  4RLA A;  1CEV A;  4Q3R C;  4FCK A;  4DZ4 A;  4GSV A;  1P8N A;  1P8O A;  1T4P A;  4MYN A;  3MFV A;  3SJT A;  1P8S A;  4Q3U A;  1WOG A;  5HJA A;  1HQG A;  2AEB A;  4IE2 A;  1TBL A;  4ITY A;  1ZPE A;  3THE A;  4GWC A;  1TBH A;  1HQX A;  4HWW A;  4IU1 A;  4Q40 A;  3NIP A;  1ZPG A;  3NIO A;  4MYK A;  5HJ9 A;  4Q42 A;  1P8P A;  3GMZ A;  3LHL A;  3MMR A;  2EIV A;  1T5F A;  3MJL A;  3E9B A;  4RHQ A;  3E6V A;  2PHO A;  3MFW A;  4IU4 A;  2PHA A;  4Q3S A;  3SL1 A;  4IE1 A;  4G3H A;  4RHJ A;  1T5G A;  4IE3 A;  2A0M A;  1P8Q A;  4Q3Q A;  4FCI A;  1HQ5 A;  4MXR A;  4RHK A;  4RHL A;  4IXV A;  2EF4 A;  4IU5 A;  3E8Z A;  3THH A;  5RLA A;  1P8R A;  1T4T A;  1PQ3 A;  3DJ8 A;  3GN0 A; 
#chains in the Genus database with same CATH topology
 3CEV A;  1T4R A;  5D1C A;  3Q9C A;  4QA7 A;  4QA3 A;  5EEI A;  1T64 A;  4ZUP A;  1TA1 A;  3Q9F A;  5G1A A;  4LXZ A;  2VQV A;  3PZL A;  4MYL A;  5EEN A;  3F0R A;  1WVB A;  2PLL A;  5G1C A;  1TBJ A;  1HQF A;  5A2S A;  4HXQ A;  3SL0 A;  4Q41 A;  4CBT A;  4CQF A;  3NIQ A;  2RLA A;  1HQH A;  3EW8 A;  3MZ4 A;  4BZ5 A;  4ZUQ A;  4MYF A;  4BKX B;  5JI5 A;  3MEN A;  1R1O A;  5G17 A;  3ZNR A;  2V5X A;  4I06 A;  4RHI A;  3TH7 A;  1P8M A;  1WOI A;  3KV2 A;  3RLA A;  5G13 A;  4GWD A;  5THV A;  3MZ3 A;  5D1D A;  5G3W A;  3Q9B A;  3E8Q A;  3MAX A;  3MZ7 A;  2CEV A;  1T4S A;  3GN0 A;  4QA2 A;  3EWF A;  4Q3V A;  5DC5 A;  1WOH A;  3LP4 A;  1GQ7 A;  5G12 A;  5G1B A;  3RQD A;  3TF3 A;  4Q3P A;  4Q3R A;  5EF8 A;  5G0H A;  4HZE A;  4GSZ A;  4CEV A;  5ICN B;  4Q3T A;  4RHM A;  4ZUR A;  4ZUN A;  2VQQ A;  3EZT A;  2VQW G;  4IXU A;  3SKK A;  5LI3 A;  3THJ A;  1GQ6 A;  1ZZ0 A;  4BZ6 A;  4QA1 A;  3F80 A;  2ZAV A;  3F06 A;  3M1R A;  5IWG A;  5EEM A;  4RN2 A;  5EFB D;  4A69 A;  1RLA A;  5CEV A;  5EFG A;  1XFK A;  3MZ6 A;  1D3V A;  2EF5 A;  4GSM A;  1WVA A;  5EFJ D;  3F07 A;  5THS A;  4IU0 A;  3LP7 A;  3C0Y A;  4RLA A;  1CEV A;  2VQM A;  1C3P A;  4Q3R C;  4ZUM A;  4FCK A;  5G11 A;  1C3S A;  4DZ4 A;  4GSV A;  1P8N A;  1P8O A;  1T4P A;  1W22 A;  1ZZ1 A;  2VQJ A;  4MYN A;  2VQO A;  5IX0 A;  3C10 A;  5G0I A;  3ZNS A;  3MFV A;  3SJT A;  1P8S A;  5G0J A;  4Q3U A;  1WOG A;  5HJA A;  1HQG A;  4RN0 A;  2AEB A;  5D1B A;  4IE2 A;  1TBL A;  5G0G A;  5EFH A;  4ITY A;  1ZPE A;  3THE A;  1C3R A;  4GWC A;  5DC8 A;  2VCG A;  5EFN A;  1TBH A;  1HQX A;  4HWW A;  4IU1 A;  4Q40 A;  3NIP A;  1ZPG A;  3NIO A;  5EEF A;  4LY1 A;  4MYK A;  1T67 A;  4Q42 A;  5HJ9 A;  1P8P A;  2GH6 A;  3GMZ A;  3LHL A;  5THT A;  4CBY A;  3MMR A;  2EIV A;  1T5F A;  5FUE A;  5THU A;  3MJL A;  3E9B A;  3Q9E A;  4RHQ A;  4RN1 A;  3E6V A;  2PHO A;  3MFW A;  4IU4 A;  2PHA A;  4Q3S A;  3SL1 A;  4IE1 A;  5G0Y A;  5DC6 A;  4G3H A;  4RHJ A;  5EF7 A;  1T5G A;  4IE3 A;  3SFH A;  4BZ8 A;  5BWZ A;  2V5W A;  3EZP A;  2A0M A;  1P8Q A;  4Q3Q A;  4QA4 A;  4FCI A;  5EFK B;  3SFF A;  4BZ9 A;  1T69 A;  1HQ5 A;  4MXR A;  4RHK A;  5FCW A;  4ZUO A;  4RHL A;  4QA0 A;  4QA5 A;  4IXV A;  2EF4 A;  4IU5 A;  4QA6 A;  1VKG A;  3E8Z A;  1ZZ3 A;  5RLA A;  1P8R A;  1T4T A;  3THH A;  5DC7 A;  5G0X A;  4BZ7 A;  5G10 A;  3C0Z A;  1PQ3 A;  5EEK A;  3DJ8 A;  3E6K A; 
#chains in the Genus database with same CATH homology
 3CEV A;  1T4R A;  1TA1 A;  3PZL A;  3E6K A;  4MYL A;  1WVB A;  2PLL A;  1TBJ A;  1HQF A;  4HXQ A;  3SL0 A;  4Q41 A;  3NIQ A;  2RLA A;  1HQH A;  4MYF A;  1R1O A;  4I06 A;  4RHI A;  3TH7 A;  1P8M A;  1WOI A;  3KV2 A;  3RLA A;  4GWD A;  3E8Q A;  2CEV A;  1T4S A;  4Q3V A;  1WOH A;  3LP4 A;  1GQ7 A;  3TF3 A;  4Q3P A;  4Q3R A;  4HZE A;  4GSZ A;  4CEV A;  4Q3T A;  4RHM A;  4IXU A;  3SKK A;  3THJ A;  1GQ6 A;  3F80 A;  2ZAV A;  3M1R A;  1RLA A;  5CEV A;  1XFK A;  1D3V A;  2EF5 A;  4GSM A;  1WVA A;  4IU0 A;  3LP7 A;  4RLA A;  1CEV A;  4Q3R C;  4FCK A;  4DZ4 A;  4GSV A;  1P8N A;  1P8O A;  1T4P A;  4MYN A;  3MFV A;  3SJT A;  1P8S A;  4Q3U A;  1WOG A;  5HJA A;  1HQG A;  2AEB A;  4IE2 A;  1TBL A;  4ITY A;  1ZPE A;  3THE A;  4GWC A;  1TBH A;  1HQX A;  4HWW A;  4IU1 A;  4Q40 A;  3NIP A;  1ZPG A;  3NIO A;  4MYK A;  5HJ9 A;  4Q42 A;  1P8P A;  3GMZ A;  3LHL A;  3MMR A;  2EIV A;  1T5F A;  3MJL A;  3E9B A;  4RHQ A;  3E6V A;  2PHO A;  3MFW A;  4IU4 A;  2PHA A;  4Q3S A;  3SL1 A;  4IE1 A;  4G3H A;  4RHJ A;  1T5G A;  4IE3 A;  2A0M A;  1P8Q A;  4Q3Q A;  4FCI A;  1HQ5 A;  4MXR A;  4RHK A;  4RHL A;  4IXV A;  2EF4 A;  4IU5 A;  3E8Z A;  3THH A;  5RLA A;  1P8R A;  1T4T A;  1PQ3 A;  3DJ8 A;  3GN0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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