3THHA

Crystal structure of the co2+2-hai-abh complex
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
314
structure length
314
Chain Sequence
RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of complexes with cobalt-reconstituted human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 112
structure length 314
sequence length 314
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2011-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 3thhA00
3CEVA 3NIOA 1P8QA 2AEBA 1TBJA 3PZLA 4MYFA 4Q3QA 1P8NA 1TA1A 1HQGA 3E6VA 4Q3UA 1RLAA 4IXUA 1ZPEA 3TH7A 1WOHA 1HQXA 4HZEA 4GSVA 4Q3PA 4Q3VA 4RHJA 1T4SA 1PQ3A 4MYNA 4Q42A 5RLAA 3THEA 3DJ8A 1T5GA 2A0MA 2PHAA 4GSMA 4ITYA 1HQHA 3SL0A 3MFWA 5CEVA 1HQFA 3MMRA 2CEVA 1P8RA 2EF4A 1WOGA 4Q3RC 3LP4A 3SKKA 3THJA 4MXRA 4Q40A 3GMZA 1T4TA 1P8OA 4IE1A 1ZPGA 3THHA 4G3HA 4IE3A 3NIQA 1T4PA 1T4RA 4DZ4A 4HWWA 2EIVA 3SL1A 1TBLA 2PHOA 1D3VA 1WVAA 3TF3A 3NIPA 1T5FA 5HJ9A 4Q41A 4Q3SA 4IU4A 4GWCA 4HXQA 4IE2A 4FCKA 4GWDA 1P8SA 4RHMA 4CEVA 3SJTA 3F80A 4RLAA 1P8MA 5HJAA 3E9BA 2RLAA 4IU5A 3M1RA 1R1OA 3GN0A 1GQ6A 4RHKA 4Q3TA 4RHQA 2PLLA 1TBHA 4IXVA 1XFKA 4FCIA 4IU1A 1GQ7A 1P8PA 1CEVA 1WOIA 3E8QA 4I06A 3LP7A 1HQ5A 3LHLA 4Q3RA 4GSZA 3E8ZA 3KV2A 3MFVA 3MJLA 4RHLA 4IU0A 3RLAA 4MYKA 2ZAVA 3E6KA 2EF5A 4MYLA 1WVBA 4RHIA
chains in the Genus database with same CATH superfamily
3CEVA 5EEIA 3NIOA 4QA7A 1P8QA 5D1CA 2AEBA 4A69A 1T69A 1TBJA 3ZNSA 4BZ5A 5EFHA 3PZLA 4MYFA 4Q3QA 5EF7A 5FUEA 1P8NA 5EFGA 5EF8A 1TA1A 1HQGA 3E6VA 4CBTA 4Q3UA 1RLAA 3EW8A 1W22A 3MZ6A 4IXUA 4LXZA 5G1AA 1ZPEA 5G17A 3EZPA 4RN2A 3TH7A 2V5WA 1WOHA 5THTA 1HQXA 2VQJA 4HZEA 4BZ6A 5FCWA 5LI3A 5DC5A 4GSVA 4Q3PA 4Q3VA 4RHJA 4ZURA 1T4SA 1PQ3A 4MYNA 5DC6A 4Q42A 5RLAA 3THEA 3DJ8A 4QA0A 5G1BA 5BWZA 5JI5A 5G1CA 1T5GA 4BKXB 1C3SA 2A0MA 4LY1A 2PHAA 4GSMA 4ITYA 4QA5A 1HQHA 5EEKA 4ZUPA 4RN0A 3SL0A 3MFWA 1VKGA 1HQFA 5CEVA 3MMRA 2CEVA 4CQFA 3Q9FA 1P8RA 3EWFA 2EF4A 5EEFA 4ZUNA 1WOGA 2VQMA 3MENA 4Q3RC 3LP4A 3SKKA 5EEMA 4MXRA 3THJA 5ICNB 2V5XA 4ZUQA 4Q40A 3Q9EA 3GMZA 3C0YA 1T4TA 2GH6A 3RQDA 1P8OA 3SFFA 4IE1A 1ZPGA 1T67A 5A2SA 3THHA 4G3HA 4IE3A 3NIQA 1T4PA 1T64A 1T4RA 3F06A 3MZ7A 4HWWA 2EIVA 4DZ4A 3MZ3A 4RHIA 1TBLA 1ZZ0A 2PHOA 3SL1A 5D1DA 1D3VA 5G0HA 5THVA 2VCGA 1WVAA 5EFJD 3TF3A 5DC7A 3NIPA 1T5FA 3Q9CA 4QA3A 1C3RA 5HJ9A 4Q41A 5G0GA 4Q3SA 3C10A 4IU4A 4QA4A 4GWCA 5G10A 4HXQA 4BZ8A 3Q9BA 4QA1A 4RN1A 4ZUMA 5G0IA 4IE2A 5EFNA 4FCKA 4GWDA 1P8SA 4RHMA 4CEVA 3SFHA 5G13A 5EENA 5G12A 3ZNRA 3SJTA 3F80A 4RLAA 1P8MA 5HJAA 3MZ4A 4BZ9A 3E9BA 5THUA 2RLAA 1C3PA 3EZTA 3MAXA 4IU5A 5G3WA 3M1RA 1R1OA 5G0XA 3GN0A 1GQ6A 4QA6A 4RHKA 5DC8A 5IWGA 4Q3TA 4RHQA 2PLLA 5D1BA 2VQWG 1TBHA 3F0RA 1ZZ3A 4CBYA 3F07A 4IXVA 5EFKB 1XFKA 4FCIA 4IU1A 5IX0A 1GQ7A 5G11A 5THSA 1P8PA 1CEVA 1WOIA 3E8QA 4I06A 2VQVA 3LP7A 3C0ZA 1HQ5A 3LHLA 2VQOA 4Q3RA 5EFBD 5G0YA 4GSZA 3E8ZA 5G0JA 3KV2A 4ZUOA 3MFVA 4BZ7A 3MJLA 4RHLA 4IU0A 3RLAA 4MYKA 2ZAVA 4QA2A 3E6KA 2EF5A 4MYLA 1WVBA 1ZZ1A 2VQQA
chains in the Genus database with same CATH topology
3CEVA 3NIOA 1P8QA 2AEBA 1TBJA 3PZLA 4MYFA 4Q3QA 1P8NA 1TA1A 1HQGA 3E6VA 4Q3UA 1RLAA 4IXUA 1ZPEA 3TH7A 1WOHA 1HQXA 4HZEA 4GSVA 4Q3PA 4Q3VA 4RHJA 1T4SA 1PQ3A 4MYNA 4Q42A 5RLAA 3THEA 3DJ8A 1T5GA 2A0MA 2PHAA 4GSMA 4ITYA 1HQHA 3SL0A 3MFWA 5CEVA 1HQFA 3MMRA 2CEVA 1P8RA 2EF4A 1WOGA 4Q3RC 3LP4A 3SKKA 3THJA 4MXRA 4Q40A 3GMZA 1T4TA 1P8OA 4IE1A 1ZPGA 3THHA 4G3HA 4IE3A 3NIQA 1T4PA 1T4RA 4DZ4A 4HWWA 2EIVA 3SL1A 1TBLA 2PHOA 1D3VA 1WVAA 3TF3A 3NIPA 1T5FA 5HJ9A 4Q41A 4Q3SA 4IU4A 4GWCA 4HXQA 4IE2A 4FCKA 4GWDA 1P8SA 4RHMA 4CEVA 3SJTA 3F80A 4RLAA 1P8MA 5HJAA 3E9BA 2RLAA 4IU5A 3M1RA 1R1OA 3GN0A 1GQ6A 4RHKA 4Q3TA 4RHQA 2PLLA 1TBHA 4IXVA 1XFKA 4FCIA 4IU1A 1GQ7A 1P8PA 1CEVA 1WOIA 3E8QA 4I06A 3LP7A 1HQ5A 3LHLA 4Q3RA 4GSZA 3E8ZA 3KV2A 3MFVA 3MJLA 4RHLA 4IU0A 3RLAA 4MYKA 2ZAVA 3E6KA 2EF5A 4MYLA 1WVBA 4RHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CEV A;  3NIO A;  1P8Q A;  2AEB A;  1TBJ A;  3PZL A;  4MYF A;  4Q3Q A;  1P8N A;  1TA1 A;  1HQG A;  3E6V A;  4Q3U A;  1RLA A;  4IXU A;  1ZPE A;  3TH7 A;  1WOH A;  1HQX A;  4HZE A;  4GSV A;  4Q3P A;  4Q3V A;  4RHJ A;  1T4S A;  1PQ3 A;  4MYN A;  4Q42 A;  5RLA A;  3THE A;  3DJ8 A;  1T5G A;  2A0M A;  2PHA A;  4GSM A;  4ITY A;  1HQH A;  3SL0 A;  3MFW A;  5CEV A;  1HQF A;  3MMR A;  2CEV A;  1P8R A;  2EF4 A;  1WOG A;  4Q3R C;  3LP4 A;  3SKK A;  3THJ A;  4MXR A;  4Q40 A;  3GMZ A;  1T4T A;  1P8O A;  4IE1 A;  1ZPG A;  3THH A;  4G3H A;  4IE3 A;  3NIQ A;  1T4P A;  1T4R A;  4DZ4 A;  4HWW A;  2EIV A;  3SL1 A;  1TBL A;  2PHO A;  1D3V A;  1WVA A;  3TF3 A;  3NIP A;  1T5F A;  5HJ9 A;  4Q41 A;  4Q3S A;  4IU4 A;  4GWC A;  4HXQ A;  4IE2 A;  4FCK A;  4GWD A;  1P8S A;  4RHM A;  4CEV A;  3SJT A;  3F80 A;  4RLA A;  1P8M A;  5HJA A;  3E9B A;  2RLA A;  4IU5 A;  3M1R A;  1R1O A;  3GN0 A;  1GQ6 A;  4RHK A;  4Q3T A;  4RHQ A;  2PLL A;  1TBH A;  4IXV A;  1XFK A;  4FCI A;  4IU1 A;  1GQ7 A;  1P8P A;  1CEV A;  1WOI A;  3E8Q A;  4I06 A;  3LP7 A;  1HQ5 A;  3LHL A;  4Q3R A;  4GSZ A;  3E8Z A;  3KV2 A;  3MFV A;  3MJL A;  4RHL A;  4IU0 A;  3RLA A;  4MYK A;  2ZAV A;  3E6K A;  2EF5 A;  4MYL A;  1WVB A;  4RHI A; 
#chains in the Genus database with same CATH topology
 3CEV A;  5EEI A;  3NIO A;  4QA7 A;  1P8Q A;  5D1C A;  2AEB A;  4A69 A;  1T69 A;  1TBJ A;  3ZNS A;  4BZ5 A;  5EFH A;  3PZL A;  4MYF A;  4Q3Q A;  5EF7 A;  5FUE A;  1P8N A;  5EFG A;  5EF8 A;  1TA1 A;  1HQG A;  3E6V A;  4CBT A;  4Q3U A;  1RLA A;  3EW8 A;  1W22 A;  3MZ6 A;  4IXU A;  4LXZ A;  5G1A A;  1ZPE A;  5G17 A;  3EZP A;  4RN2 A;  3TH7 A;  2V5W A;  1WOH A;  5THT A;  1HQX A;  2VQJ A;  4HZE A;  4BZ6 A;  5FCW A;  5LI3 A;  5DC5 A;  4GSV A;  4Q3P A;  4Q3V A;  4RHJ A;  4ZUR A;  1T4S A;  1PQ3 A;  4MYN A;  5DC6 A;  4Q42 A;  5RLA A;  3THE A;  3DJ8 A;  4QA0 A;  5G1B A;  5BWZ A;  5JI5 A;  5G1C A;  1T5G A;  4BKX B;  1C3S A;  2A0M A;  4LY1 A;  2PHA A;  4GSM A;  4ITY A;  4QA5 A;  1HQH A;  5EEK A;  4ZUP A;  4RN0 A;  3SL0 A;  3MFW A;  1VKG A;  1HQF A;  5CEV A;  3MMR A;  2CEV A;  4CQF A;  3Q9F A;  1P8R A;  3EWF A;  2EF4 A;  5EEF A;  4ZUN A;  1WOG A;  2VQM A;  3MEN A;  4Q3R C;  3LP4 A;  3SKK A;  5EEM A;  4MXR A;  3THJ A;  5ICN B;  2V5X A;  4ZUQ A;  4Q40 A;  3Q9E A;  3GMZ A;  3C0Y A;  1T4T A;  2GH6 A;  3RQD A;  1P8O A;  3SFF A;  4IE1 A;  1ZPG A;  1T67 A;  5A2S A;  3THH A;  4G3H A;  4IE3 A;  3NIQ A;  1T4P A;  1T64 A;  1T4R A;  3F06 A;  3MZ7 A;  4HWW A;  2EIV A;  4DZ4 A;  3MZ3 A;  4RHI A;  1TBL A;  1ZZ0 A;  2PHO A;  3SL1 A;  5D1D A;  1D3V A;  5G0H A;  5THV A;  2VCG A;  1WVA A;  5EFJ D;  3TF3 A;  5DC7 A;  3NIP A;  1T5F A;  3Q9C A;  4QA3 A;  1C3R A;  5HJ9 A;  4Q41 A;  5G0G A;  4Q3S A;  3C10 A;  4IU4 A;  4QA4 A;  4GWC A;  5G10 A;  4HXQ A;  4BZ8 A;  3Q9B A;  4QA1 A;  4RN1 A;  4ZUM A;  5G0I A;  4IE2 A;  5EFN A;  4FCK A;  4GWD A;  1P8S A;  4RHM A;  4CEV A;  3SFH A;  5G13 A;  5EEN A;  5G12 A;  3ZNR A;  3SJT A;  3F80 A;  4RLA A;  1P8M A;  5HJA A;  3MZ4 A;  4BZ9 A;  3E9B A;  5THU A;  2RLA A;  1C3P A;  3EZT A;  3MAX A;  4IU5 A;  5G3W A;  3M1R A;  1R1O A;  5G0X A;  3GN0 A;  1GQ6 A;  4QA6 A;  4RHK A;  5DC8 A;  5IWG A;  4Q3T A;  4RHQ A;  2PLL A;  5D1B A;  2VQW G;  1TBH A;  3F0R A;  1ZZ3 A;  4CBY A;  3F07 A;  4IXV A;  5EFK B;  1XFK A;  4FCI A;  4IU1 A;  5IX0 A;  1GQ7 A;  5G11 A;  5THS A;  1P8P A;  1CEV A;  1WOI A;  3E8Q A;  4I06 A;  2VQV A;  3LP7 A;  3C0Z A;  1HQ5 A;  3LHL A;  2VQO A;  4Q3R A;  5EFB D;  5G0Y A;  4GSZ A;  3E8Z A;  5G0J A;  3KV2 A;  4ZUO A;  3MFV A;  4BZ7 A;  3MJL A;  4RHL A;  4IU0 A;  3RLA A;  4MYK A;  2ZAV A;  4QA2 A;  3E6K A;  2EF5 A;  4MYL A;  1WVB A;  1ZZ1 A;  2VQQ A; 
#chains in the Genus database with same CATH homology
 3CEV A;  3NIO A;  1P8Q A;  2AEB A;  1TBJ A;  3PZL A;  4MYF A;  4Q3Q A;  1P8N A;  1TA1 A;  1HQG A;  3E6V A;  4Q3U A;  1RLA A;  4IXU A;  1ZPE A;  3TH7 A;  1WOH A;  1HQX A;  4HZE A;  4GSV A;  4Q3P A;  4Q3V A;  4RHJ A;  1T4S A;  1PQ3 A;  4MYN A;  4Q42 A;  5RLA A;  3THE A;  3DJ8 A;  1T5G A;  2A0M A;  2PHA A;  4GSM A;  4ITY A;  1HQH A;  3SL0 A;  3MFW A;  5CEV A;  1HQF A;  3MMR A;  2CEV A;  1P8R A;  2EF4 A;  1WOG A;  4Q3R C;  3LP4 A;  3SKK A;  3THJ A;  4MXR A;  4Q40 A;  3GMZ A;  1T4T A;  1P8O A;  4IE1 A;  1ZPG A;  3THH A;  4G3H A;  4IE3 A;  3NIQ A;  1T4P A;  1T4R A;  4DZ4 A;  4HWW A;  2EIV A;  3SL1 A;  1TBL A;  2PHO A;  1D3V A;  1WVA A;  3TF3 A;  3NIP A;  1T5F A;  5HJ9 A;  4Q41 A;  4Q3S A;  4IU4 A;  4GWC A;  4HXQ A;  4IE2 A;  4FCK A;  4GWD A;  1P8S A;  4RHM A;  4CEV A;  3SJT A;  3F80 A;  4RLA A;  1P8M A;  5HJA A;  3E9B A;  2RLA A;  4IU5 A;  3M1R A;  1R1O A;  3GN0 A;  1GQ6 A;  4RHK A;  4Q3T A;  4RHQ A;  2PLL A;  1TBH A;  4IXV A;  1XFK A;  4FCI A;  4IU1 A;  1GQ7 A;  1P8P A;  1CEV A;  1WOI A;  3E8Q A;  4I06 A;  3LP7 A;  1HQ5 A;  3LHL A;  4Q3R A;  4GSZ A;  3E8Z A;  3KV2 A;  3MFV A;  3MJL A;  4RHL A;  4IU0 A;  3RLA A;  4MYK A;  2ZAV A;  3E6K A;  2EF5 A;  4MYL A;  1WVB A;  4RHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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