4CEVA

Arginase from bacillus caldevelox, l-ornithine complex
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
298
structure length
298
Chain Sequence
KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLMAAAAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 112
structure length 298
sequence length 298
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4cevA00
1P8MA 5HJAA 3GMZA 4GWCA 4MYFA 1WVAA 3SL0A 4Q3PA 1P8PA 3MFWA 5CEVA 2PHOA 4RLAA 4G3HA 3E9BA 1TBJA 4RHQA 1P8SA 4Q3UA 1T5GA 1ZPEA 4Q3TA 3LHLA 4IXUA 4MXRA 4Q3RA 4Q3RC 1PQ3A 3THEA 1T4RA 3E8QA 3NIOA 4RHIA 2PHAA 1P8OA 4IE3A 4RHLA 4IU5A 1HQXA 1ZPGA 3E6KA 4ITYA 4Q3QA 3SKKA 3MJLA 1R1OA 1TBLA 4CEVA 1RLAA 1T4PA 3PZLA 3CEVA 2CEVA 3MFVA 1P8NA 1HQFA 2A0MA 1D3VA 3F80A 3E6VA 4IU1A 1WOGA 4IU4A 3THHA 4IU0A 4HWWA 3KV2A 4FCIA 5HJ9A 3NIPA 2ZAVA 1WVBA 3SL1A 1HQ5A 3E8ZA 4RHJA 5RLAA 4GWDA 4GSZA 1GQ7A 4HZEA 1P8RA 3LP7A 4Q41A 4FCKA 4IE1A 4GSMA 1TA1A 2PLLA 4Q3VA 1WOIA 4MYKA 1T4TA 3NIQA 3SJTA 3MMRA 2AEBA 2EF4A 4IXVA 4I06A 4HXQA 1TBHA 3GN0A 3TH7A 4IE2A 4MYNA 1HQGA 4DZ4A 3M1RA 4GSVA 1WOHA 1CEVA 1T4SA 1T5FA 1XFKA 2EIVA 3LP4A 1GQ6A 1P8QA 4MYLA 3RLAA 4RHMA 3TF3A 3THJA 4Q40A 3DJ8A 4RHKA 1HQHA 2RLAA 4Q42A 2EF5A 4Q3SA
chains in the Genus database with same CATH superfamily
1P8MA 5G0GA 3GMZA 5HJAA 5EEKA 4GWCA 4MYFA 1WVAA 5EEFA 4QA4A 3SL0A 5EEMA 2VQQA 4Q3PA 5FUEA 5G1AA 1P8PA 3MFWA 5THUA 5EFBD 4CBYA 5D1CA 5CEVA 3F06A 2PHOA 4RLAA 4ZUMA 3RQDA 4BZ9A 4G3HA 3ZNRA 1T67A 3E9BA 1TBJA 4RHQA 5G0YA 4ZUPA 1P8SA 4Q3UA 5THVA 1T5GA 1ZPEA 2V5WA 2VQJA 4Q3TA 3LHLA 5D1BA 4QA2A 4RN2A 5G10A 5THSA 3Q9CA 2GH6A 4IXUA 4MXRA 4Q3RA 1W22A 4RN0A 4Q3RC 1PQ3A 4QA0A 4BZ8A 5DC5A 5EENA 5G13A 3THEA 1T4RA 3MAXA 3E8QA 3NIOA 3ZNSA 4RHIA 5DC8A 2PHAA 5G11A 1P8OA 5FCWA 4IE3A 4RHLA 5IWGA 5EFNA 3Q9BA 4IU5A 1HQXA 1ZPGA 5G1BA 3E6KA 5LI3A 1C3RA 5G17A 5G12A 4ITYA 4Q3QA 3SKKA 1T69A 3EW8A 3MJLA 4LXZA 3SFHA 5G1CA 1R1OA 3SFFA 1TBLA 2V5XA 4ZUOA 4CEVA 5G0XA 5JI5A 3EZPA 1T64A 2VQOA 3MZ7A 1RLAA 5EEIA 4BZ7A 4LY1A 1ZZ0A 5EFJD 1T4PA 3PZLA 3CEVA 4ZURA 2CEVA 3C0ZA 3C0YA 3MFVA 5EF8A 3MZ3A 4QA7A 1P8NA 1HQFA 2VQMA 2A0MA 1D3VA 3F80A 3E6VA 4IU1A 1WOGA 4IU4A 3THHA 4QA6A 1C3SA 4IU0A 4HWWA 3KV2A 4FCIA 5HJ9A 3NIPA 2ZAVA 1WVBA 5EFGA 3SL1A 1HQ5A 5D1DA 3E8ZA 4RHJA 5RLAA 4GWDA 4GSZA 3F07A 1GQ7A 4HZEA 3MZ4A 5EF7A 5G0IA 1P8RA 3LP7A 4QA1A 4CBTA 4BKXB 3MZ6A 4Q41A 4FCKA 5THTA 4IE1A 3F0RA 4GSMA 1TA1A 2PLLA 1ZZ3A 4Q3VA 1WOIA 1C3PA 4MYKA 2VCGA 1T4TA 5EFKB 4CQFA 4A69A 3NIQA 3SJTA 3MMRA 2VQVA 2AEBA 2EF4A 4IXVA 5G0HA 4I06A 4HXQA 5DC6A 3Q9FA 1TBHA 4BZ6A 3GN0A 3TH7A 4IE2A 3C10A 5EFHA 5G0JA 4MYNA 1HQGA 4DZ4A 4ZUNA 3M1RA 4GSVA 1WOHA 1CEVA 5BWZA 4QA3A 1ZZ1A 1T4SA 1T5FA 3EZTA 2VQWG 1XFKA 5G3WA 5A2SA 1VKGA 2EIVA 3LP4A 5IX0A 1GQ6A 1P8QA 4MYLA 4QA5A 3RLAA 4RHMA 3MENA 3TF3A 3THJA 4Q40A 4ZUQA 3DJ8A 4RHKA 1HQHA 4RN1A 2RLAA 4Q42A 4BZ5A 5DC7A 5ICNB 2EF5A 3EWFA 4Q3SA 3Q9EA
chains in the Genus database with same CATH topology
1P8MA 5HJAA 3GMZA 4GWCA 4MYFA 1WVAA 3SL0A 4Q3PA 1P8PA 3MFWA 5CEVA 2PHOA 4RLAA 4G3HA 3E9BA 1TBJA 4RHQA 1P8SA 4Q3UA 1T5GA 1ZPEA 4Q3TA 3LHLA 4IXUA 4MXRA 4Q3RA 4Q3RC 1PQ3A 3THEA 1T4RA 3E8QA 3NIOA 4RHIA 2PHAA 1P8OA 4IE3A 4RHLA 4IU5A 1HQXA 1ZPGA 3E6KA 4ITYA 4Q3QA 3SKKA 3MJLA 1R1OA 1TBLA 4CEVA 1RLAA 1T4PA 3PZLA 3CEVA 2CEVA 3MFVA 1P8NA 1HQFA 2A0MA 1D3VA 3F80A 3E6VA 4IU1A 1WOGA 4IU4A 3THHA 4IU0A 4HWWA 3KV2A 4FCIA 5HJ9A 3NIPA 2ZAVA 1WVBA 3SL1A 1HQ5A 3E8ZA 4RHJA 5RLAA 4GWDA 4GSZA 1GQ7A 4HZEA 1P8RA 3LP7A 4Q41A 4FCKA 4IE1A 4GSMA 1TA1A 2PLLA 4Q3VA 1WOIA 4MYKA 1T4TA 3NIQA 3SJTA 3MMRA 2AEBA 2EF4A 4IXVA 4I06A 4HXQA 1TBHA 3GN0A 3TH7A 4IE2A 4MYNA 1HQGA 4DZ4A 3M1RA 4GSVA 1WOHA 1CEVA 1T4SA 1T5FA 1XFKA 2EIVA 3LP4A 1GQ6A 1P8QA 4MYLA 3RLAA 4RHMA 3TF3A 3THJA 4Q40A 3DJ8A 4RHKA 1HQHA 2RLAA 4Q42A 2EF5A 4Q3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8M A;  5HJA A;  3GMZ A;  4GWC A;  4MYF A;  1WVA A;  3SL0 A;  4Q3P A;  1P8P A;  3MFW A;  5CEV A;  2PHO A;  4RLA A;  4G3H A;  3E9B A;  1TBJ A;  4RHQ A;  1P8S A;  4Q3U A;  1T5G A;  1ZPE A;  4Q3T A;  3LHL A;  4IXU A;  4MXR A;  4Q3R A;  4Q3R C;  1PQ3 A;  3THE A;  1T4R A;  3E8Q A;  3NIO A;  4RHI A;  2PHA A;  1P8O A;  4IE3 A;  4RHL A;  4IU5 A;  1HQX A;  1ZPG A;  3E6K A;  4ITY A;  4Q3Q A;  3SKK A;  3MJL A;  1R1O A;  1TBL A;  4CEV A;  1RLA A;  1T4P A;  3PZL A;  3CEV A;  2CEV A;  3MFV A;  1P8N A;  1HQF A;  2A0M A;  1D3V A;  3F80 A;  3E6V A;  4IU1 A;  1WOG A;  4IU4 A;  3THH A;  4IU0 A;  4HWW A;  3KV2 A;  4FCI A;  5HJ9 A;  3NIP A;  2ZAV A;  1WVB A;  3SL1 A;  1HQ5 A;  3E8Z A;  4RHJ A;  5RLA A;  4GWD A;  4GSZ A;  1GQ7 A;  4HZE A;  1P8R A;  3LP7 A;  4Q41 A;  4FCK A;  4IE1 A;  4GSM A;  1TA1 A;  2PLL A;  4Q3V A;  1WOI A;  4MYK A;  1T4T A;  3NIQ A;  3SJT A;  3MMR A;  2AEB A;  2EF4 A;  4IXV A;  4I06 A;  4HXQ A;  1TBH A;  3GN0 A;  3TH7 A;  4IE2 A;  4MYN A;  1HQG A;  4DZ4 A;  3M1R A;  4GSV A;  1WOH A;  1CEV A;  1T4S A;  1T5F A;  1XFK A;  2EIV A;  3LP4 A;  1GQ6 A;  1P8Q A;  4MYL A;  3RLA A;  4RHM A;  3TF3 A;  3THJ A;  4Q40 A;  3DJ8 A;  4RHK A;  1HQH A;  2RLA A;  4Q42 A;  2EF5 A;  4Q3S A; 
#chains in the Genus database with same CATH topology
 1P8M A;  5G0G A;  3GMZ A;  5HJA A;  5EEK A;  4GWC A;  4MYF A;  1WVA A;  5EEF A;  4QA4 A;  3SL0 A;  5EEM A;  2VQQ A;  4Q3P A;  5FUE A;  5G1A A;  1P8P A;  3MFW A;  5THU A;  5EFB D;  4CBY A;  5D1C A;  5CEV A;  3F06 A;  2PHO A;  4RLA A;  4ZUM A;  3RQD A;  4BZ9 A;  4G3H A;  3ZNR A;  1T67 A;  3E9B A;  1TBJ A;  4RHQ A;  5G0Y A;  4ZUP A;  1P8S A;  4Q3U A;  5THV A;  1T5G A;  1ZPE A;  2V5W A;  2VQJ A;  4Q3T A;  3LHL A;  5D1B A;  4QA2 A;  4RN2 A;  5G10 A;  5THS A;  3Q9C A;  2GH6 A;  4IXU A;  4MXR A;  4Q3R A;  1W22 A;  4RN0 A;  4Q3R C;  1PQ3 A;  4QA0 A;  4BZ8 A;  5DC5 A;  5EEN A;  5G13 A;  3THE A;  1T4R A;  3MAX A;  3E8Q A;  3NIO A;  3ZNS A;  4RHI A;  5DC8 A;  2PHA A;  5G11 A;  1P8O A;  5FCW A;  4IE3 A;  4RHL A;  5IWG A;  5EFN A;  3Q9B A;  4IU5 A;  1HQX A;  1ZPG A;  5G1B A;  3E6K A;  5LI3 A;  1C3R A;  5G17 A;  5G12 A;  4ITY A;  4Q3Q A;  3SKK A;  1T69 A;  3EW8 A;  3MJL A;  4LXZ A;  3SFH A;  5G1C A;  1R1O A;  3SFF A;  1TBL A;  2V5X A;  4ZUO A;  4CEV A;  5G0X A;  5JI5 A;  3EZP A;  1T64 A;  2VQO A;  3MZ7 A;  1RLA A;  5EEI A;  4BZ7 A;  4LY1 A;  1ZZ0 A;  5EFJ D;  1T4P A;  3PZL A;  3CEV A;  4ZUR A;  2CEV A;  3C0Z A;  3C0Y A;  3MFV A;  5EF8 A;  3MZ3 A;  4QA7 A;  1P8N A;  1HQF A;  2VQM A;  2A0M A;  1D3V A;  3F80 A;  3E6V A;  4IU1 A;  1WOG A;  4IU4 A;  3THH A;  4QA6 A;  1C3S A;  4IU0 A;  4HWW A;  3KV2 A;  4FCI A;  5HJ9 A;  3NIP A;  2ZAV A;  1WVB A;  5EFG A;  3SL1 A;  1HQ5 A;  5D1D A;  3E8Z A;  4RHJ A;  5RLA A;  4GWD A;  4GSZ A;  3F07 A;  1GQ7 A;  4HZE A;  3MZ4 A;  5EF7 A;  5G0I A;  1P8R A;  3LP7 A;  4QA1 A;  4CBT A;  4BKX B;  3MZ6 A;  4Q41 A;  4FCK A;  5THT A;  4IE1 A;  3F0R A;  4GSM A;  1TA1 A;  2PLL A;  1ZZ3 A;  4Q3V A;  1WOI A;  1C3P A;  4MYK A;  2VCG A;  1T4T A;  5EFK B;  4CQF A;  4A69 A;  3NIQ A;  3SJT A;  3MMR A;  2VQV A;  2AEB A;  2EF4 A;  4IXV A;  5G0H A;  4I06 A;  4HXQ A;  5DC6 A;  3Q9F A;  1TBH A;  4BZ6 A;  3GN0 A;  3TH7 A;  4IE2 A;  3C10 A;  5EFH A;  5G0J A;  4MYN A;  1HQG A;  4DZ4 A;  4ZUN A;  3M1R A;  4GSV A;  1WOH A;  1CEV A;  5BWZ A;  4QA3 A;  1ZZ1 A;  1T4S A;  1T5F A;  3EZT A;  2VQW G;  1XFK A;  5G3W A;  5A2S A;  1VKG A;  2EIV A;  3LP4 A;  5IX0 A;  1GQ6 A;  1P8Q A;  4MYL A;  4QA5 A;  3RLA A;  4RHM A;  3MEN A;  3TF3 A;  3THJ A;  4Q40 A;  4ZUQ A;  3DJ8 A;  4RHK A;  1HQH A;  4RN1 A;  2RLA A;  4Q42 A;  4BZ5 A;  5DC7 A;  5ICN B;  2EF5 A;  3EWF A;  4Q3S A;  3Q9E A; 
#chains in the Genus database with same CATH homology
 1P8M A;  5HJA A;  3GMZ A;  4GWC A;  4MYF A;  1WVA A;  3SL0 A;  4Q3P A;  1P8P A;  3MFW A;  5CEV A;  2PHO A;  4RLA A;  4G3H A;  3E9B A;  1TBJ A;  4RHQ A;  1P8S A;  4Q3U A;  1T5G A;  1ZPE A;  4Q3T A;  3LHL A;  4IXU A;  4MXR A;  4Q3R A;  4Q3R C;  1PQ3 A;  3THE A;  1T4R A;  3E8Q A;  3NIO A;  4RHI A;  2PHA A;  1P8O A;  4IE3 A;  4RHL A;  4IU5 A;  1HQX A;  1ZPG A;  3E6K A;  4ITY A;  4Q3Q A;  3SKK A;  3MJL A;  1R1O A;  1TBL A;  4CEV A;  1RLA A;  1T4P A;  3PZL A;  3CEV A;  2CEV A;  3MFV A;  1P8N A;  1HQF A;  2A0M A;  1D3V A;  3F80 A;  3E6V A;  4IU1 A;  1WOG A;  4IU4 A;  3THH A;  4IU0 A;  4HWW A;  3KV2 A;  4FCI A;  5HJ9 A;  3NIP A;  2ZAV A;  1WVB A;  3SL1 A;  1HQ5 A;  3E8Z A;  4RHJ A;  5RLA A;  4GWD A;  4GSZ A;  1GQ7 A;  4HZE A;  1P8R A;  3LP7 A;  4Q41 A;  4FCK A;  4IE1 A;  4GSM A;  1TA1 A;  2PLL A;  4Q3V A;  1WOI A;  4MYK A;  1T4T A;  3NIQ A;  3SJT A;  3MMR A;  2AEB A;  2EF4 A;  4IXV A;  4I06 A;  4HXQ A;  1TBH A;  3GN0 A;  3TH7 A;  4IE2 A;  4MYN A;  1HQG A;  4DZ4 A;  3M1R A;  4GSV A;  1WOH A;  1CEV A;  1T4S A;  1T5F A;  1XFK A;  2EIV A;  3LP4 A;  1GQ6 A;  1P8Q A;  4MYL A;  3RLA A;  4RHM A;  3TF3 A;  3THJ A;  4Q40 A;  3DJ8 A;  4RHK A;  1HQH A;  2RLA A;  4Q42 A;  2EF5 A;  4Q3S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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