4GSZA

Crystal structure of the zn2+5-human arginase i-abh complex
Total Genus 109
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Arginase-1
total genus 109
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gszA00
3GN0A 4MYFA 1WVAA 3LP7A 3E6VA 1WOHA 4ITYA 3M1RA 1P8PA 4IE3A 1ZPGA 1HQHA 1HQ5A 4MXRA 4RHKA 2EF4A 4HXQA 4Q40A 4Q41A 3THEA 4IU0A 5RLAA 3THHA 4RHLA 1CEVA 4RHQA 3LP4A 1XFKA 4Q42A 1D3VA 4IU4A 4Q3TA 2RLAA 2AEBA 4HWWA 2A0MA 3GMZA 4FCIA 1P8OA 1HQXA 2EIVA 3MFVA 4GSZA 4GWDA 3MJLA 1WOIA 1ZPEA 1T5FA 1T5GA 4IE2A 1P8RA 4IXVA 1RLAA 1P8NA 3CEVA 4RHJA 2PHAA 3KV2A 3TF3A 1R1OA 1P8SA 4RHIA 1PQ3A 2PLLA 3NIPA 4IXUA 2CEVA 2ZAVA 1HQGA 3E9BA 4IU1A 4Q3RA 1TBHA 3E6KA 1P8QA 3THJA 4Q3VA 3MMRA 3PZLA 3TH7A 1T4PA 1P8MA 4FCKA 1WOGA 4Q3RC 4Q3QA 5CEVA 1GQ7A 1TBJA 4MYNA 4GSVA 2PHOA 3F80A 4G3HA 4HZEA 4Q3SA 1WVBA 4IU5A 3MFWA 4MYKA 3NIQA 3RLAA 3LHLA 1T4TA 1TA1A 5HJ9A 1TBLA 4Q3PA 4I06A 1T4RA 4IE1A 4GWCA 3SKKA 5HJAA 3DJ8A 4Q3UA 4DZ4A 4RHMA 4GSMA 3SL0A 4MYLA 3SJTA 1HQFA 3E8ZA 3E8QA 3NIOA 4RLAA 4CEVA 1T4SA 1GQ6A 3SL1A 2EF5A
chains in the Genus database with same CATH superfamily
3Q9BA 4QA5A 3GN0A 4MYFA 1WVAA 5EFJD 4RN2A 5EEMA 3LP7A 3E6VA 4QA1A 1WOHA 2VQMA 5G0JA 3ZNRA 4ITYA 3M1RA 1P8PA 5IWGA 1ZZ3A 4IE3A 1ZPGA 1HQHA 1HQ5A 5G3WA 3F07A 4MXRA 4RHKA 3Q9FA 2EF4A 4HXQA 4BZ5A 4Q40A 4QA3A 5A2SA 5ICNB 4Q41A 3THEA 4IU0A 5EEKA 3EWFA 5RLAA 3SFFA 3THHA 4RHLA 3C10A 1CEVA 4RHQA 3LP4A 5G12A 5LI3A 1XFKA 4Q42A 1C3RA 1D3VA 5JI5A 5FCWA 1ZZ1A 4IU4A 5G1AA 3F06A 4BZ9A 5EFNA 5THTA 3EZTA 5G0IA 2V5WA 5EEIA 4Q3TA 2RLAA 2AEBA 4BZ6A 1C3SA 5EFKB 2VQWG 3C0ZA 5G13A 5THSA 4CBYA 5DC7A 4HWWA 2VQJA 2A0MA 5EFBD 3GMZA 4FCIA 1P8OA 1HQXA 2EIVA 3EW8A 3MFVA 4GSZA 4GWDA 3MJLA 5G1CA 1WOIA 1ZPEA 3EZPA 1T5FA 4LY1A 1T5GA 4IE2A 1VKGA 4ZUPA 1P8RA 4IXVA 5G0XA 5G0GA 5DC8A 4BZ7A 1RLAA 1P8NA 3CEVA 4RHJA 2PHAA 3KV2A 2VQOA 3TF3A 1R1OA 4QA7A 1P8SA 4RHIA 4CBTA 1T67A 4QA4A 5THVA 3ZNSA 1PQ3A 2PLLA 3MZ7A 3NIPA 4IXUA 5D1DA 1T69A 4RN1A 5G1BA 3SFHA 2CEVA 2ZAVA 1HQGA 3E9BA 4IU1A 4Q3RA 5DC5A 1TBHA 3E6KA 1P8QA 5DC6A 3THJA 4Q3VA 5G0YA 3RQDA 3MMRA 3PZLA 3TH7A 5G0HA 5THUA 1T4PA 5EENA 5EF7A 5BWZA 1P8MA 1ZZ0A 2VCGA 3Q9EA 4FCKA 5G11A 1WOGA 4BKXB 3MENA 5EEFA 4CQFA 4Q3RC 4Q3QA 5CEVA 2V5XA 1GQ7A 1TBJA 4MYNA 4ZUOA 1W22A 1C3PA 4GSVA 4QA6A 2PHOA 5FUEA 1T64A 3F0RA 4BZ8A 3F80A 4G3HA 3MZ4A 4HZEA 1WVBA 4LXZA 4Q3SA 5EFHA 4ZUMA 2VQQA 4IU5A 2VQVA 3MFWA 3MZ6A 4MYKA 4A69A 3NIQA 3RLAA 3LHLA 3MZ3A 1T4TA 5IX0A 1TA1A 4ZUQA 5HJ9A 4QA0A 4ZUNA 1TBLA 3MAXA 4Q3PA 5EF8A 5EFGA 5D1CA 4I06A 5G10A 1T4RA 3Q9CA 4GWCA 4IE1A 2GH6A 4RN0A 3DJ8A 4Q3UA 3SKKA 4DZ4A 5D1BA 5HJAA 4RHMA 4GSMA 3SL0A 4ZURA 4MYLA 4QA2A 5G17A 3SJTA 3C0YA 1HQFA 3E8ZA 3E8QA 3NIOA 4RLAA 4CEVA 1T4SA 1GQ6A 3SL1A 2EF5A
chains in the Genus database with same CATH topology
3GN0A 4MYFA 1WVAA 3LP7A 3E6VA 1WOHA 4ITYA 3M1RA 1P8PA 4IE3A 1ZPGA 1HQHA 1HQ5A 4MXRA 4RHKA 2EF4A 4HXQA 4Q40A 4Q41A 3THEA 4IU0A 5RLAA 3THHA 4RHLA 1CEVA 4RHQA 3LP4A 1XFKA 4Q42A 1D3VA 4IU4A 4Q3TA 2RLAA 2AEBA 4HWWA 2A0MA 3GMZA 4FCIA 1P8OA 1HQXA 2EIVA 3MFVA 4GSZA 4GWDA 3MJLA 1WOIA 1ZPEA 1T5FA 1T5GA 4IE2A 1P8RA 4IXVA 1RLAA 1P8NA 3CEVA 4RHJA 2PHAA 3KV2A 3TF3A 1R1OA 1P8SA 4RHIA 1PQ3A 2PLLA 3NIPA 4IXUA 2CEVA 2ZAVA 1HQGA 3E9BA 4IU1A 4Q3RA 1TBHA 3E6KA 1P8QA 3THJA 4Q3VA 3MMRA 3PZLA 3TH7A 1T4PA 1P8MA 4FCKA 1WOGA 4Q3RC 4Q3QA 5CEVA 1GQ7A 1TBJA 4MYNA 4GSVA 2PHOA 3F80A 4G3HA 4HZEA 4Q3SA 1WVBA 4IU5A 3MFWA 4MYKA 3NIQA 3RLAA 3LHLA 1T4TA 1TA1A 5HJ9A 1TBLA 4Q3PA 4I06A 1T4RA 4IE1A 4GWCA 3SKKA 5HJAA 3DJ8A 4Q3UA 4DZ4A 4RHMA 4GSMA 3SL0A 4MYLA 3SJTA 1HQFA 3E8ZA 3E8QA 3NIOA 4RLAA 4CEVA 1T4SA 1GQ6A 3SL1A 2EF5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GN0 A;  4MYF A;  1WVA A;  3LP7 A;  3E6V A;  1WOH A;  4ITY A;  3M1R A;  1P8P A;  4IE3 A;  1ZPG A;  1HQH A;  1HQ5 A;  4MXR A;  4RHK A;  2EF4 A;  4HXQ A;  4Q40 A;  4Q41 A;  3THE A;  4IU0 A;  5RLA A;  3THH A;  4RHL A;  1CEV A;  4RHQ A;  3LP4 A;  1XFK A;  4Q42 A;  1D3V A;  4IU4 A;  4Q3T A;  2RLA A;  2AEB A;  4HWW A;  2A0M A;  3GMZ A;  4FCI A;  1P8O A;  1HQX A;  2EIV A;  3MFV A;  4GSZ A;  4GWD A;  3MJL A;  1WOI A;  1ZPE A;  1T5F A;  1T5G A;  4IE2 A;  1P8R A;  4IXV A;  1RLA A;  1P8N A;  3CEV A;  4RHJ A;  2PHA A;  3KV2 A;  3TF3 A;  1R1O A;  1P8S A;  4RHI A;  1PQ3 A;  2PLL A;  3NIP A;  4IXU A;  2CEV A;  2ZAV A;  1HQG A;  3E9B A;  4IU1 A;  4Q3R A;  1TBH A;  3E6K A;  1P8Q A;  3THJ A;  4Q3V A;  3MMR A;  3PZL A;  3TH7 A;  1T4P A;  1P8M A;  4FCK A;  1WOG A;  4Q3R C;  4Q3Q A;  5CEV A;  1GQ7 A;  1TBJ A;  4MYN A;  4GSV A;  2PHO A;  3F80 A;  4G3H A;  4HZE A;  4Q3S A;  1WVB A;  4IU5 A;  3MFW A;  4MYK A;  3NIQ A;  3RLA A;  3LHL A;  1T4T A;  1TA1 A;  5HJ9 A;  1TBL A;  4Q3P A;  4I06 A;  1T4R A;  4IE1 A;  4GWC A;  3SKK A;  5HJA A;  3DJ8 A;  4Q3U A;  4DZ4 A;  4RHM A;  4GSM A;  3SL0 A;  4MYL A;  3SJT A;  1HQF A;  3E8Z A;  3E8Q A;  3NIO A;  4RLA A;  4CEV A;  1T4S A;  1GQ6 A;  3SL1 A;  2EF5 A; 
#chains in the Genus database with same CATH topology
 3Q9B A;  4QA5 A;  3GN0 A;  4MYF A;  1WVA A;  5EFJ D;  4RN2 A;  5EEM A;  3LP7 A;  3E6V A;  4QA1 A;  1WOH A;  2VQM A;  5G0J A;  3ZNR A;  4ITY A;  3M1R A;  1P8P A;  5IWG A;  1ZZ3 A;  4IE3 A;  1ZPG A;  1HQH A;  1HQ5 A;  5G3W A;  3F07 A;  4MXR A;  4RHK A;  3Q9F A;  2EF4 A;  4HXQ A;  4BZ5 A;  4Q40 A;  4QA3 A;  5A2S A;  5ICN B;  4Q41 A;  3THE A;  4IU0 A;  5EEK A;  3EWF A;  5RLA A;  3SFF A;  3THH A;  4RHL A;  3C10 A;  1CEV A;  4RHQ A;  3LP4 A;  5G12 A;  5LI3 A;  1XFK A;  4Q42 A;  1C3R A;  1D3V A;  5JI5 A;  5FCW A;  1ZZ1 A;  4IU4 A;  5G1A A;  3F06 A;  4BZ9 A;  5EFN A;  5THT A;  3EZT A;  5G0I A;  2V5W A;  5EEI A;  4Q3T A;  2RLA A;  2AEB A;  4BZ6 A;  1C3S A;  5EFK B;  2VQW G;  3C0Z A;  5G13 A;  5THS A;  4CBY A;  5DC7 A;  4HWW A;  2VQJ A;  2A0M A;  5EFB D;  3GMZ A;  4FCI A;  1P8O A;  1HQX A;  2EIV A;  3EW8 A;  3MFV A;  4GSZ A;  4GWD A;  3MJL A;  5G1C A;  1WOI A;  1ZPE A;  3EZP A;  1T5F A;  4LY1 A;  1T5G A;  4IE2 A;  1VKG A;  4ZUP A;  1P8R A;  4IXV A;  5G0X A;  5G0G A;  5DC8 A;  4BZ7 A;  1RLA A;  1P8N A;  3CEV A;  4RHJ A;  2PHA A;  3KV2 A;  2VQO A;  3TF3 A;  1R1O A;  4QA7 A;  1P8S A;  4RHI A;  4CBT A;  1T67 A;  4QA4 A;  5THV A;  3ZNS A;  1PQ3 A;  2PLL A;  3MZ7 A;  3NIP A;  4IXU A;  5D1D A;  1T69 A;  4RN1 A;  5G1B A;  3SFH A;  2CEV A;  2ZAV A;  1HQG A;  3E9B A;  4IU1 A;  4Q3R A;  5DC5 A;  1TBH A;  3E6K A;  1P8Q A;  5DC6 A;  3THJ A;  4Q3V A;  5G0Y A;  3RQD A;  3MMR A;  3PZL A;  3TH7 A;  5G0H A;  5THU A;  1T4P A;  5EEN A;  5EF7 A;  5BWZ A;  1P8M A;  1ZZ0 A;  2VCG A;  3Q9E A;  4FCK A;  5G11 A;  1WOG A;  4BKX B;  3MEN A;  5EEF A;  4CQF A;  4Q3R C;  4Q3Q A;  5CEV A;  2V5X A;  1GQ7 A;  1TBJ A;  4MYN A;  4ZUO A;  1W22 A;  1C3P A;  4GSV A;  4QA6 A;  2PHO A;  5FUE A;  1T64 A;  3F0R A;  4BZ8 A;  3F80 A;  4G3H A;  3MZ4 A;  4HZE A;  1WVB A;  4LXZ A;  4Q3S A;  5EFH A;  4ZUM A;  2VQQ A;  4IU5 A;  2VQV A;  3MFW A;  3MZ6 A;  4MYK A;  4A69 A;  3NIQ A;  3RLA A;  3LHL A;  3MZ3 A;  1T4T A;  5IX0 A;  1TA1 A;  4ZUQ A;  5HJ9 A;  4QA0 A;  4ZUN A;  1TBL A;  3MAX A;  4Q3P A;  5EF8 A;  5EFG A;  5D1C A;  4I06 A;  5G10 A;  1T4R A;  3Q9C A;  4GWC A;  4IE1 A;  2GH6 A;  4RN0 A;  3DJ8 A;  4Q3U A;  3SKK A;  4DZ4 A;  5D1B A;  5HJA A;  4RHM A;  4GSM A;  3SL0 A;  4ZUR A;  4MYL A;  4QA2 A;  5G17 A;  3SJT A;  3C0Y A;  1HQF A;  3E8Z A;  3E8Q A;  3NIO A;  4RLA A;  4CEV A;  1T4S A;  1GQ6 A;  3SL1 A;  2EF5 A; 
#chains in the Genus database with same CATH homology
 3GN0 A;  4MYF A;  1WVA A;  3LP7 A;  3E6V A;  1WOH A;  4ITY A;  3M1R A;  1P8P A;  4IE3 A;  1ZPG A;  1HQH A;  1HQ5 A;  4MXR A;  4RHK A;  2EF4 A;  4HXQ A;  4Q40 A;  4Q41 A;  3THE A;  4IU0 A;  5RLA A;  3THH A;  4RHL A;  1CEV A;  4RHQ A;  3LP4 A;  1XFK A;  4Q42 A;  1D3V A;  4IU4 A;  4Q3T A;  2RLA A;  2AEB A;  4HWW A;  2A0M A;  3GMZ A;  4FCI A;  1P8O A;  1HQX A;  2EIV A;  3MFV A;  4GSZ A;  4GWD A;  3MJL A;  1WOI A;  1ZPE A;  1T5F A;  1T5G A;  4IE2 A;  1P8R A;  4IXV A;  1RLA A;  1P8N A;  3CEV A;  4RHJ A;  2PHA A;  3KV2 A;  3TF3 A;  1R1O A;  1P8S A;  4RHI A;  1PQ3 A;  2PLL A;  3NIP A;  4IXU A;  2CEV A;  2ZAV A;  1HQG A;  3E9B A;  4IU1 A;  4Q3R A;  1TBH A;  3E6K A;  1P8Q A;  3THJ A;  4Q3V A;  3MMR A;  3PZL A;  3TH7 A;  1T4P A;  1P8M A;  4FCK A;  1WOG A;  4Q3R C;  4Q3Q A;  5CEV A;  1GQ7 A;  1TBJ A;  4MYN A;  4GSV A;  2PHO A;  3F80 A;  4G3H A;  4HZE A;  4Q3S A;  1WVB A;  4IU5 A;  3MFW A;  4MYK A;  3NIQ A;  3RLA A;  3LHL A;  1T4T A;  1TA1 A;  5HJ9 A;  1TBL A;  4Q3P A;  4I06 A;  1T4R A;  4IE1 A;  4GWC A;  3SKK A;  5HJA A;  3DJ8 A;  4Q3U A;  4DZ4 A;  4RHM A;  4GSM A;  3SL0 A;  4MYL A;  3SJT A;  1HQF A;  3E8Z A;  3E8Q A;  3NIO A;  4RLA A;  4CEV A;  1T4S A;  1GQ6 A;  3SL1 A;  2EF5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...