4GWCA

Crystal structure of mn2+2,zn2+-human arginase i
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 104
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gwcA00
4RLAA 4GSVA 4Q3SA 3E6KA 1T4SA 4DZ4A 1WVBA 3E9BA 4IXUA 1TBHA 1T4RA 1CEVA 2EF4A 4HZEA 1P8RA 4FCKA 3MFVA 1WOGA 3PZLA 3SL1A 1RLAA 4MYLA 4Q3RA 3E8QA 4IE3A 1P8OA 2CEVA 1T4PA 2ZAVA 1T4TA 3NIPA 1ZPEA 4ITYA 3KV2A 3SJTA 1WOHA 2EIVA 2PHOA 3GN0A 3THJA 1GQ7A 3NIOA 3GMZA 4GSMA 3RLAA 2PHAA 4MYFA 4GSZA 4MYNA 1ZPGA 1GQ6A 3TH7A 3DJ8A 3E6VA 3THEA 3NIQA 5HJ9A 2A0MA 1P8MA 4CEVA 4Q3PA 4HXQA 4Q3UA 1PQ3A 1T5GA 4HWWA 4GWDA 2RLAA 4Q41A 4RHQA 4GWCA 3F80A 4Q3TA 3MMRA 5RLAA 1WVAA 1T5FA 3E8ZA 4RHMA 4IE1A 4I06A 3SL0A 4Q3VA 3SKKA 4RHKA 1P8QA 4IU0A 1D3VA 4MXRA 4G3HA 4RHLA 4RHIA 1HQGA 1HQXA 2AEBA 2EF5A 1HQFA 4Q40A 3LP4A 4FCIA 2PLLA 1P8NA 4RHJA 4MYKA 1TBJA 1TBLA 1P8PA 4IU5A 4IU4A 4Q3RC 1P8SA 4Q3QA 3M1RA 5CEVA 4IE2A 1TA1A 3LP7A 3TF3A 1XFKA 3LHLA 1HQHA 1R1OA 4IU1A 4Q42A 3MJLA 3MFWA 4IXVA 3CEVA 1HQ5A 5HJAA 1WOIA 3THHA
chains in the Genus database with same CATH superfamily
2VQVA 4GSVA 4RLAA 5G1CA 4Q3SA 1C3SA 3E6KA 2VQJA 3Q9EA 5LI3A 3F06A 5THTA 4RN2A 1T4SA 4DZ4A 3RQDA 1WVBA 3E9BA 1T64A 4IXUA 4BZ5A 1TBHA 1T4RA 1CEVA 2VQQA 2EF4A 4HZEA 1P8RA 4FCKA 3MFVA 5EEIA 5EFBD 2V5XA 1WOGA 3PZLA 3SL1A 1RLAA 5G17A 5EEFA 5EFGA 4MYLA 4Q3RA 3E8QA 5G0HA 5FCWA 4IE3A 1P8OA 2CEVA 5A2SA 1T4PA 2ZAVA 3EWFA 2V5WA 1C3RA 1T4TA 1C3PA 3C0YA 4LY1A 3NIPA 1ZPEA 4RN0A 5G0IA 4ITYA 3KV2A 2GH6A 5EF7A 5EEKA 3MZ4A 5EEMA 3SJTA 4QA7A 1WOHA 2EIVA 2PHOA 5JI5A 3GN0A 4RN1A 2VQWG 1GQ7A 3NIOA 3EW8A 3GMZA 4QA6A 4QA3A 3Q9BA 4GSMA 3EZPA 5G0XA 3RLAA 2PHAA 4MYFA 4BZ9A 5ICNB 4CBTA 4GSZA 5EFKB 4MYNA 3MAXA 1ZPGA 1GQ6A 4ZUNA 3TH7A 3DJ8A 4BZ7A 3E6VA 3THEA 2VQOA 3NIQA 5BWZA 1ZZ3A 5HJ9A 2A0MA 5IWGA 1P8MA 4CEVA 4A69A 4BZ8A 5G0JA 4Q3PA 4HXQA 4Q3UA 1PQ3A 1T5GA 4HWWA 4QA4A 5DC5A 3ZNRA 4ZUPA 5D1DA 3SFFA 4GWDA 2RLAA 4QA0A 5G0GA 5D1BA 4Q41A 4RHQA 4GWCA 1ZZ0A 5FUEA 2VCGA 3F80A 4Q3TA 3EZTA 3MMRA 5G3WA 5RLAA 4QA5A 1WVAA 1T5FA 3E8ZA 4QA1A 4RHMA 4IE1A 5EFHA 5THSA 1T69A 5D1CA 4I06A 3SL0A 4Q3VA 5IX0A 3SKKA 5THVA 4RHKA 1P8QA 4IU0A 1D3VA 3C0ZA 4G3HA 4MXRA 3C10A 4RHLA 2VQMA 4LXZA 4RHIA 3Q9FA 3MZ7A 5G1AA 1HQGA 1HQXA 2AEBA 5DC7A 2EF5A 1HQFA 4Q40A 3ZNSA 3LP4A 3MENA 4FCIA 3THJA 2PLLA 5DC6A 3F07A 4CBYA 5G13A 1P8NA 4RHJA 4ZUOA 4MYKA 1TBJA 1TBLA 5G0YA 1P8PA 4IU5A 3MZ6A 1ZZ1A 4IU4A 4Q3RC 1P8SA 4Q3QA 3M1RA 4ZURA 3Q9CA 5G1BA 5CEVA 4IE2A 1TA1A 3LP7A 3TF3A 3SFHA 5DC8A 1XFKA 3LHLA 5G11A 5G12A 1T67A 5G10A 1HQHA 1R1OA 4ZUQA 4BZ6A 5EFJD 4QA2A 3MZ3A 4IU1A 4Q42A 3MJLA 3MFWA 4IXVA 4BKXB 5EF8A 1VKGA 3CEVA 3F0RA 1W22A 5EFNA 5THUA 1HQ5A 5EENA 5HJAA 1WOIA 3THHA 4ZUMA 4CQFA
chains in the Genus database with same CATH topology
4RLAA 4GSVA 4Q3SA 3E6KA 1T4SA 4DZ4A 1WVBA 3E9BA 4IXUA 1TBHA 1T4RA 1CEVA 2EF4A 4HZEA 1P8RA 4FCKA 3MFVA 1WOGA 3PZLA 3SL1A 1RLAA 4MYLA 4Q3RA 3E8QA 4IE3A 1P8OA 2CEVA 1T4PA 2ZAVA 1T4TA 3NIPA 1ZPEA 4ITYA 3KV2A 3SJTA 1WOHA 2EIVA 2PHOA 3GN0A 3THJA 1GQ7A 3NIOA 3GMZA 4GSMA 3RLAA 2PHAA 4MYFA 4GSZA 4MYNA 1ZPGA 1GQ6A 3TH7A 3DJ8A 3E6VA 3THEA 3NIQA 5HJ9A 2A0MA 1P8MA 4CEVA 4Q3PA 4HXQA 4Q3UA 1PQ3A 1T5GA 4HWWA 4GWDA 2RLAA 4Q41A 4RHQA 4GWCA 3F80A 4Q3TA 3MMRA 5RLAA 1WVAA 1T5FA 3E8ZA 4RHMA 4IE1A 4I06A 3SL0A 4Q3VA 3SKKA 4RHKA 1P8QA 4IU0A 1D3VA 4MXRA 4G3HA 4RHLA 4RHIA 1HQGA 1HQXA 2AEBA 2EF5A 1HQFA 4Q40A 3LP4A 4FCIA 2PLLA 1P8NA 4RHJA 4MYKA 1TBJA 1TBLA 1P8PA 4IU5A 4IU4A 4Q3RC 1P8SA 4Q3QA 3M1RA 5CEVA 4IE2A 1TA1A 3LP7A 3TF3A 1XFKA 3LHLA 1HQHA 1R1OA 4IU1A 4Q42A 3MJLA 3MFWA 4IXVA 3CEVA 1HQ5A 5HJAA 1WOIA 3THHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RLA A;  4GSV A;  4Q3S A;  3E6K A;  1T4S A;  4DZ4 A;  1WVB A;  3E9B A;  4IXU A;  1TBH A;  1T4R A;  1CEV A;  2EF4 A;  4HZE A;  1P8R A;  4FCK A;  3MFV A;  1WOG A;  3PZL A;  3SL1 A;  1RLA A;  4MYL A;  4Q3R A;  3E8Q A;  4IE3 A;  1P8O A;  2CEV A;  1T4P A;  2ZAV A;  1T4T A;  3NIP A;  1ZPE A;  4ITY A;  3KV2 A;  3SJT A;  1WOH A;  2EIV A;  2PHO A;  3GN0 A;  3THJ A;  1GQ7 A;  3NIO A;  3GMZ A;  4GSM A;  3RLA A;  2PHA A;  4MYF A;  4GSZ A;  4MYN A;  1ZPG A;  1GQ6 A;  3TH7 A;  3DJ8 A;  3E6V A;  3THE A;  3NIQ A;  5HJ9 A;  2A0M A;  1P8M A;  4CEV A;  4Q3P A;  4HXQ A;  4Q3U A;  1PQ3 A;  1T5G A;  4HWW A;  4GWD A;  2RLA A;  4Q41 A;  4RHQ A;  4GWC A;  3F80 A;  4Q3T A;  3MMR A;  5RLA A;  1WVA A;  1T5F A;  3E8Z A;  4RHM A;  4IE1 A;  4I06 A;  3SL0 A;  4Q3V A;  3SKK A;  4RHK A;  1P8Q A;  4IU0 A;  1D3V A;  4MXR A;  4G3H A;  4RHL A;  4RHI A;  1HQG A;  1HQX A;  2AEB A;  2EF5 A;  1HQF A;  4Q40 A;  3LP4 A;  4FCI A;  2PLL A;  1P8N A;  4RHJ A;  4MYK A;  1TBJ A;  1TBL A;  1P8P A;  4IU5 A;  4IU4 A;  4Q3R C;  1P8S A;  4Q3Q A;  3M1R A;  5CEV A;  4IE2 A;  1TA1 A;  3LP7 A;  3TF3 A;  1XFK A;  3LHL A;  1HQH A;  1R1O A;  4IU1 A;  4Q42 A;  3MJL A;  3MFW A;  4IXV A;  3CEV A;  1HQ5 A;  5HJA A;  1WOI A;  3THH A; 
#chains in the Genus database with same CATH topology
 2VQV A;  4GSV A;  4RLA A;  5G1C A;  4Q3S A;  1C3S A;  3E6K A;  2VQJ A;  3Q9E A;  5LI3 A;  3F06 A;  5THT A;  4RN2 A;  1T4S A;  4DZ4 A;  3RQD A;  1WVB A;  3E9B A;  1T64 A;  4IXU A;  4BZ5 A;  1TBH A;  1T4R A;  1CEV A;  2VQQ A;  2EF4 A;  4HZE A;  1P8R A;  4FCK A;  3MFV A;  5EEI A;  5EFB D;  2V5X A;  1WOG A;  3PZL A;  3SL1 A;  1RLA A;  5G17 A;  5EEF A;  5EFG A;  4MYL A;  4Q3R A;  3E8Q A;  5G0H A;  5FCW A;  4IE3 A;  1P8O A;  2CEV A;  5A2S A;  1T4P A;  2ZAV A;  3EWF A;  2V5W A;  1C3R A;  1T4T A;  1C3P A;  3C0Y A;  4LY1 A;  3NIP A;  1ZPE A;  4RN0 A;  5G0I A;  4ITY A;  3KV2 A;  2GH6 A;  5EF7 A;  5EEK A;  3MZ4 A;  5EEM A;  3SJT A;  4QA7 A;  1WOH A;  2EIV A;  2PHO A;  5JI5 A;  3GN0 A;  4RN1 A;  2VQW G;  1GQ7 A;  3NIO A;  3EW8 A;  3GMZ A;  4QA6 A;  4QA3 A;  3Q9B A;  4GSM A;  3EZP A;  5G0X A;  3RLA A;  2PHA A;  4MYF A;  4BZ9 A;  5ICN B;  4CBT A;  4GSZ A;  5EFK B;  4MYN A;  3MAX A;  1ZPG A;  1GQ6 A;  4ZUN A;  3TH7 A;  3DJ8 A;  4BZ7 A;  3E6V A;  3THE A;  2VQO A;  3NIQ A;  5BWZ A;  1ZZ3 A;  5HJ9 A;  2A0M A;  5IWG A;  1P8M A;  4CEV A;  4A69 A;  4BZ8 A;  5G0J A;  4Q3P A;  4HXQ A;  4Q3U A;  1PQ3 A;  1T5G A;  4HWW A;  4QA4 A;  5DC5 A;  3ZNR A;  4ZUP A;  5D1D A;  3SFF A;  4GWD A;  2RLA A;  4QA0 A;  5G0G A;  5D1B A;  4Q41 A;  4RHQ A;  4GWC A;  1ZZ0 A;  5FUE A;  2VCG A;  3F80 A;  4Q3T A;  3EZT A;  3MMR A;  5G3W A;  5RLA A;  4QA5 A;  1WVA A;  1T5F A;  3E8Z A;  4QA1 A;  4RHM A;  4IE1 A;  5EFH A;  5THS A;  1T69 A;  5D1C A;  4I06 A;  3SL0 A;  4Q3V A;  5IX0 A;  3SKK A;  5THV A;  4RHK A;  1P8Q A;  4IU0 A;  1D3V A;  3C0Z A;  4G3H A;  4MXR A;  3C10 A;  4RHL A;  2VQM A;  4LXZ A;  4RHI A;  3Q9F A;  3MZ7 A;  5G1A A;  1HQG A;  1HQX A;  2AEB A;  5DC7 A;  2EF5 A;  1HQF A;  4Q40 A;  3ZNS A;  3LP4 A;  3MEN A;  4FCI A;  3THJ A;  2PLL A;  5DC6 A;  3F07 A;  4CBY A;  5G13 A;  1P8N A;  4RHJ A;  4ZUO A;  4MYK A;  1TBJ A;  1TBL A;  5G0Y A;  1P8P A;  4IU5 A;  3MZ6 A;  1ZZ1 A;  4IU4 A;  4Q3R C;  1P8S A;  4Q3Q A;  3M1R A;  4ZUR A;  3Q9C A;  5G1B A;  5CEV A;  4IE2 A;  1TA1 A;  3LP7 A;  3TF3 A;  3SFH A;  5DC8 A;  1XFK A;  3LHL A;  5G11 A;  5G12 A;  1T67 A;  5G10 A;  1HQH A;  1R1O A;  4ZUQ A;  4BZ6 A;  5EFJ D;  4QA2 A;  3MZ3 A;  4IU1 A;  4Q42 A;  3MJL A;  3MFW A;  4IXV A;  4BKX B;  5EF8 A;  1VKG A;  3CEV A;  3F0R A;  1W22 A;  5EFN A;  5THU A;  1HQ5 A;  5EEN A;  5HJA A;  1WOI A;  3THH A;  4ZUM A;  4CQF A; 
#chains in the Genus database with same CATH homology
 4RLA A;  4GSV A;  4Q3S A;  3E6K A;  1T4S A;  4DZ4 A;  1WVB A;  3E9B A;  4IXU A;  1TBH A;  1T4R A;  1CEV A;  2EF4 A;  4HZE A;  1P8R A;  4FCK A;  3MFV A;  1WOG A;  3PZL A;  3SL1 A;  1RLA A;  4MYL A;  4Q3R A;  3E8Q A;  4IE3 A;  1P8O A;  2CEV A;  1T4P A;  2ZAV A;  1T4T A;  3NIP A;  1ZPE A;  4ITY A;  3KV2 A;  3SJT A;  1WOH A;  2EIV A;  2PHO A;  3GN0 A;  3THJ A;  1GQ7 A;  3NIO A;  3GMZ A;  4GSM A;  3RLA A;  2PHA A;  4MYF A;  4GSZ A;  4MYN A;  1ZPG A;  1GQ6 A;  3TH7 A;  3DJ8 A;  3E6V A;  3THE A;  3NIQ A;  5HJ9 A;  2A0M A;  1P8M A;  4CEV A;  4Q3P A;  4HXQ A;  4Q3U A;  1PQ3 A;  1T5G A;  4HWW A;  4GWD A;  2RLA A;  4Q41 A;  4RHQ A;  4GWC A;  3F80 A;  4Q3T A;  3MMR A;  5RLA A;  1WVA A;  1T5F A;  3E8Z A;  4RHM A;  4IE1 A;  4I06 A;  3SL0 A;  4Q3V A;  3SKK A;  4RHK A;  1P8Q A;  4IU0 A;  1D3V A;  4MXR A;  4G3H A;  4RHL A;  4RHI A;  1HQG A;  1HQX A;  2AEB A;  2EF5 A;  1HQF A;  4Q40 A;  3LP4 A;  4FCI A;  2PLL A;  1P8N A;  4RHJ A;  4MYK A;  1TBJ A;  1TBL A;  1P8P A;  4IU5 A;  4IU4 A;  4Q3R C;  1P8S A;  4Q3Q A;  3M1R A;  5CEV A;  4IE2 A;  1TA1 A;  3LP7 A;  3TF3 A;  1XFK A;  3LHL A;  1HQH A;  1R1O A;  4IU1 A;  4Q42 A;  3MJL A;  3MFW A;  4IXV A;  3CEV A;  1HQ5 A;  5HJA A;  1WOI A;  3THH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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