4GWCA

Crystal structure of mn2+2,zn2+-human arginase i
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 104
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gwcA00
4DZ4A 1ZPGA 3E6KA 3M1RA 3NIQA 4I06A 4Q40A 3RLAA 4Q3SA 3E8QA 4HWWA 3E8ZA 4IE3A 4Q3UA 4GSMA 4Q3VA 4RHKA 3DJ8A 1TBJA 4MYNA 3LP7A 1XFKA 4Q42A 1TBHA 5HJ9A 1T5FA 4CEVA 1HQXA 3CEVA 4IE1A 4MXRA 4HXQA 4Q3PA 1P8QA 3F80A 3MFWA 4Q41A 4Q3RA 2ZAVA 1WOIA 3SKKA 1P8NA 1T4RA 4RHMA 3MJLA 1HQGA 2AEBA 3E9BA 1P8SA 4IU0A 1HQFA 2CEVA 3THHA 1P8OA 3GN0A 5HJAA 3THJA 1P8PA 2PHAA 2PLLA 1HQHA 3KV2A 1PQ3A 5RLAA 1ZPEA 1R1OA 4Q3QA 1WVAA 3MMRA 4ITYA 3SL1A 4RHIA 4RHQA 4RHLA 3GMZA 4GSZA 1TBLA 1D3VA 3TF3A 1WOHA 2PHOA 4Q3TA 4GWDA 2EF4A 1T4PA 1T5GA 1HQ5A 3PZLA 1GQ7A 2A0MA 1P8MA 4GWCA 4IU4A 4RHJA 4MYKA 3LHLA 3MFVA 3E6VA 4G3HA 4IU1A 1TA1A 4IXUA 4IXVA 3THEA 1RLAA 2EIVA 3SL0A 1CEVA 3LP4A 3NIPA 1WVBA 4FCKA 4MYFA 1T4SA 4HZEA 5CEVA 4FCIA 4RLAA 1WOGA 3TH7A 2EF5A 4GSVA 1P8RA 1GQ6A 3NIOA 4IE2A 4MYLA 4Q3RC 2RLAA 4IU5A 1T4TA 3SJTA
chains in the Genus database with same CATH superfamily
4DZ4A 1ZPGA 3E6KA 5EF7A 3EWFA 3M1RA 5EF8A 3NIQA 4I06A 3MZ4A 5JI5A 3EZTA 4BZ8A 4A69A 4Q40A 4QA0A 5G1CA 3RLAA 5IWGA 4Q3SA 3E8QA 4HWWA 3E8ZA 4IE3A 5D1BA 1ZZ3A 2V5XA 4GSMA 4Q3UA 4Q3VA 3DJ8A 4RHKA 1W22A 1TBJA 4MYNA 5EFBD 5G0XA 5G13A 3RQDA 3LP7A 1XFKA 3C0ZA 4Q42A 3Q9EA 1TBHA 5HJ9A 1T5FA 4CEVA 2V5WA 3MZ3A 3MZ7A 1HQXA 4LY1A 4QA4A 5EEKA 5G0YA 3MZ6A 3CEVA 4IE1A 4MXRA 5D1DA 4HXQA 4Q3PA 1P8QA 3F80A 4QA1A 3MFWA 4RN0A 4QA7A 5EFGA 5G11A 4Q41A 5BWZA 4Q3RA 2ZAVA 1WOIA 3SKKA 5EEFA 1P8NA 1C3SA 1T4RA 4BZ7A 4RHMA 3MJLA 3SFFA 1HQGA 2AEBA 3E9BA 5LI3A 1P8SA 4IU0A 2VQMA 1HQFA 5EENA 5G17A 2CEVA 3THHA 1P8OA 2VQJA 3GN0A 5EEMA 5HJAA 3THJA 1P8PA 3C0YA 2PHAA 5FCWA 4QA6A 5EFHA 5D1CA 4BZ6A 5G3WA 5DC5A 2PLLA 1HQHA 3KV2A 4LXZA 1PQ3A 5RLAA 5IX0A 4CBYA 1VKGA 1ZPEA 3F0RA 3ZNSA 1R1OA 4Q3QA 5EFKB 1WVAA 1T67A 5G0GA 3MMRA 4ITYA 4QA3A 3SL1A 4RHIA 5G0HA 5G1BA 4RHQA 3ZNRA 4QA2A 1ZZ0A 5DC6A 4BKXB 4RHLA 2VQVA 3GMZA 4GSZA 1TBLA 5DC8A 5EFJD 1D3VA 5A2SA 3TF3A 1WOHA 2PHOA 2VQOA 2VQWG 4RN2A 4Q3TA 4GWDA 4CBTA 2EF4A 5ICNB 3MENA 2VCGA 1T4PA 1T5GA 4ZUPA 4ZURA 4BZ5A 1HQ5A 3PZLA 1GQ7A 2A0MA 1P8MA 5G1AA 5THVA 4GWCA 3SFHA 3Q9CA 4IU4A 4RHJA 4MYKA 3C10A 5EFNA 3LHLA 4ZUMA 3MFVA 5DC7A 3F07A 5FUEA 4BZ9A 3Q9FA 3MAXA 3EZPA 3E6VA 1T64A 5THTA 2VQQA 4G3HA 4IU1A 1TA1A 4IXUA 4IXVA 3THEA 5THUA 1RLAA 1T69A 5THSA 2EIVA 3EW8A 3SL0A 4ZUOA 4QA5A 1CEVA 5G0JA 4CQFA 3LP4A 3NIPA 1WVBA 3F06A 4FCKA 5G0IA 4ZUNA 4MYFA 1C3RA 1T4SA 4HZEA 5G10A 5CEVA 1C3PA 2GH6A 4FCIA 4RLAA 4ZUQA 4RN1A 5G12A 1WOGA 3TH7A 2EF5A 4GSVA 1P8RA 1GQ6A 3NIOA 4IE2A 4MYLA 4Q3RC 2RLAA 5EEIA 1ZZ1A 4IU5A 1T4TA 3Q9BA 3SJTA
chains in the Genus database with same CATH topology
4DZ4A 1ZPGA 3E6KA 3M1RA 3NIQA 4I06A 4Q40A 3RLAA 4Q3SA 3E8QA 4HWWA 3E8ZA 4IE3A 4Q3UA 4GSMA 4Q3VA 4RHKA 3DJ8A 1TBJA 4MYNA 3LP7A 1XFKA 4Q42A 1TBHA 5HJ9A 1T5FA 4CEVA 1HQXA 3CEVA 4IE1A 4MXRA 4HXQA 4Q3PA 1P8QA 3F80A 3MFWA 4Q41A 4Q3RA 2ZAVA 1WOIA 3SKKA 1P8NA 1T4RA 4RHMA 3MJLA 1HQGA 2AEBA 3E9BA 1P8SA 4IU0A 1HQFA 2CEVA 3THHA 1P8OA 3GN0A 5HJAA 3THJA 1P8PA 2PHAA 2PLLA 1HQHA 3KV2A 1PQ3A 5RLAA 1ZPEA 1R1OA 4Q3QA 1WVAA 3MMRA 4ITYA 3SL1A 4RHIA 4RHQA 4RHLA 3GMZA 4GSZA 1TBLA 1D3VA 3TF3A 1WOHA 2PHOA 4Q3TA 4GWDA 2EF4A 1T4PA 1T5GA 1HQ5A 3PZLA 1GQ7A 2A0MA 1P8MA 4GWCA 4IU4A 4RHJA 4MYKA 3LHLA 3MFVA 3E6VA 4G3HA 4IU1A 1TA1A 4IXUA 4IXVA 3THEA 1RLAA 2EIVA 3SL0A 1CEVA 3LP4A 3NIPA 1WVBA 4FCKA 4MYFA 1T4SA 4HZEA 5CEVA 4FCIA 4RLAA 1WOGA 3TH7A 2EF5A 4GSVA 1P8RA 1GQ6A 3NIOA 4IE2A 4MYLA 4Q3RC 2RLAA 4IU5A 1T4TA 3SJTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DZ4 A;  1ZPG A;  3E6K A;  3M1R A;  3NIQ A;  4I06 A;  4Q40 A;  3RLA A;  4Q3S A;  3E8Q A;  4HWW A;  3E8Z A;  4IE3 A;  4Q3U A;  4GSM A;  4Q3V A;  4RHK A;  3DJ8 A;  1TBJ A;  4MYN A;  3LP7 A;  1XFK A;  4Q42 A;  1TBH A;  5HJ9 A;  1T5F A;  4CEV A;  1HQX A;  3CEV A;  4IE1 A;  4MXR A;  4HXQ A;  4Q3P A;  1P8Q A;  3F80 A;  3MFW A;  4Q41 A;  4Q3R A;  2ZAV A;  1WOI A;  3SKK A;  1P8N A;  1T4R A;  4RHM A;  3MJL A;  1HQG A;  2AEB A;  3E9B A;  1P8S A;  4IU0 A;  1HQF A;  2CEV A;  3THH A;  1P8O A;  3GN0 A;  5HJA A;  3THJ A;  1P8P A;  2PHA A;  2PLL A;  1HQH A;  3KV2 A;  1PQ3 A;  5RLA A;  1ZPE A;  1R1O A;  4Q3Q A;  1WVA A;  3MMR A;  4ITY A;  3SL1 A;  4RHI A;  4RHQ A;  4RHL A;  3GMZ A;  4GSZ A;  1TBL A;  1D3V A;  3TF3 A;  1WOH A;  2PHO A;  4Q3T A;  4GWD A;  2EF4 A;  1T4P A;  1T5G A;  1HQ5 A;  3PZL A;  1GQ7 A;  2A0M A;  1P8M A;  4GWC A;  4IU4 A;  4RHJ A;  4MYK A;  3LHL A;  3MFV A;  3E6V A;  4G3H A;  4IU1 A;  1TA1 A;  4IXU A;  4IXV A;  3THE A;  1RLA A;  2EIV A;  3SL0 A;  1CEV A;  3LP4 A;  3NIP A;  1WVB A;  4FCK A;  4MYF A;  1T4S A;  4HZE A;  5CEV A;  4FCI A;  4RLA A;  1WOG A;  3TH7 A;  2EF5 A;  4GSV A;  1P8R A;  1GQ6 A;  3NIO A;  4IE2 A;  4MYL A;  4Q3R C;  2RLA A;  4IU5 A;  1T4T A;  3SJT A; 
#chains in the Genus database with same CATH topology
 4DZ4 A;  1ZPG A;  3E6K A;  5EF7 A;  3EWF A;  3M1R A;  5EF8 A;  3NIQ A;  4I06 A;  3MZ4 A;  5JI5 A;  3EZT A;  4BZ8 A;  4A69 A;  4Q40 A;  4QA0 A;  5G1C A;  3RLA A;  5IWG A;  4Q3S A;  3E8Q A;  4HWW A;  3E8Z A;  4IE3 A;  5D1B A;  1ZZ3 A;  2V5X A;  4GSM A;  4Q3U A;  4Q3V A;  3DJ8 A;  4RHK A;  1W22 A;  1TBJ A;  4MYN A;  5EFB D;  5G0X A;  5G13 A;  3RQD A;  3LP7 A;  1XFK A;  3C0Z A;  4Q42 A;  3Q9E A;  1TBH A;  5HJ9 A;  1T5F A;  4CEV A;  2V5W A;  3MZ3 A;  3MZ7 A;  1HQX A;  4LY1 A;  4QA4 A;  5EEK A;  5G0Y A;  3MZ6 A;  3CEV A;  4IE1 A;  4MXR A;  5D1D A;  4HXQ A;  4Q3P A;  1P8Q A;  3F80 A;  4QA1 A;  3MFW A;  4RN0 A;  4QA7 A;  5EFG A;  5G11 A;  4Q41 A;  5BWZ A;  4Q3R A;  2ZAV A;  1WOI A;  3SKK A;  5EEF A;  1P8N A;  1C3S A;  1T4R A;  4BZ7 A;  4RHM A;  3MJL A;  3SFF A;  1HQG A;  2AEB A;  3E9B A;  5LI3 A;  1P8S A;  4IU0 A;  2VQM A;  1HQF A;  5EEN A;  5G17 A;  2CEV A;  3THH A;  1P8O A;  2VQJ A;  3GN0 A;  5EEM A;  5HJA A;  3THJ A;  1P8P A;  3C0Y A;  2PHA A;  5FCW A;  4QA6 A;  5EFH A;  5D1C A;  4BZ6 A;  5G3W A;  5DC5 A;  2PLL A;  1HQH A;  3KV2 A;  4LXZ A;  1PQ3 A;  5RLA A;  5IX0 A;  4CBY A;  1VKG A;  1ZPE A;  3F0R A;  3ZNS A;  1R1O A;  4Q3Q A;  5EFK B;  1WVA A;  1T67 A;  5G0G A;  3MMR A;  4ITY A;  4QA3 A;  3SL1 A;  4RHI A;  5G0H A;  5G1B A;  4RHQ A;  3ZNR A;  4QA2 A;  1ZZ0 A;  5DC6 A;  4BKX B;  4RHL A;  2VQV A;  3GMZ A;  4GSZ A;  1TBL A;  5DC8 A;  5EFJ D;  1D3V A;  5A2S A;  3TF3 A;  1WOH A;  2PHO A;  2VQO A;  2VQW G;  4RN2 A;  4Q3T A;  4GWD A;  4CBT A;  2EF4 A;  5ICN B;  3MEN A;  2VCG A;  1T4P A;  1T5G A;  4ZUP A;  4ZUR A;  4BZ5 A;  1HQ5 A;  3PZL A;  1GQ7 A;  2A0M A;  1P8M A;  5G1A A;  5THV A;  4GWC A;  3SFH A;  3Q9C A;  4IU4 A;  4RHJ A;  4MYK A;  3C10 A;  5EFN A;  3LHL A;  4ZUM A;  3MFV A;  5DC7 A;  3F07 A;  5FUE A;  4BZ9 A;  3Q9F A;  3MAX A;  3EZP A;  3E6V A;  1T64 A;  5THT A;  2VQQ A;  4G3H A;  4IU1 A;  1TA1 A;  4IXU A;  4IXV A;  3THE A;  5THU A;  1RLA A;  1T69 A;  5THS A;  2EIV A;  3EW8 A;  3SL0 A;  4ZUO A;  4QA5 A;  1CEV A;  5G0J A;  4CQF A;  3LP4 A;  3NIP A;  1WVB A;  3F06 A;  4FCK A;  5G0I A;  4ZUN A;  4MYF A;  1C3R A;  1T4S A;  4HZE A;  5G10 A;  5CEV A;  1C3P A;  2GH6 A;  4FCI A;  4RLA A;  4ZUQ A;  4RN1 A;  5G12 A;  1WOG A;  3TH7 A;  2EF5 A;  4GSV A;  1P8R A;  1GQ6 A;  3NIO A;  4IE2 A;  4MYL A;  4Q3R C;  2RLA A;  5EEI A;  1ZZ1 A;  4IU5 A;  1T4T A;  3Q9B A;  3SJT A; 
#chains in the Genus database with same CATH homology
 4DZ4 A;  1ZPG A;  3E6K A;  3M1R A;  3NIQ A;  4I06 A;  4Q40 A;  3RLA A;  4Q3S A;  3E8Q A;  4HWW A;  3E8Z A;  4IE3 A;  4Q3U A;  4GSM A;  4Q3V A;  4RHK A;  3DJ8 A;  1TBJ A;  4MYN A;  3LP7 A;  1XFK A;  4Q42 A;  1TBH A;  5HJ9 A;  1T5F A;  4CEV A;  1HQX A;  3CEV A;  4IE1 A;  4MXR A;  4HXQ A;  4Q3P A;  1P8Q A;  3F80 A;  3MFW A;  4Q41 A;  4Q3R A;  2ZAV A;  1WOI A;  3SKK A;  1P8N A;  1T4R A;  4RHM A;  3MJL A;  1HQG A;  2AEB A;  3E9B A;  1P8S A;  4IU0 A;  1HQF A;  2CEV A;  3THH A;  1P8O A;  3GN0 A;  5HJA A;  3THJ A;  1P8P A;  2PHA A;  2PLL A;  1HQH A;  3KV2 A;  1PQ3 A;  5RLA A;  1ZPE A;  1R1O A;  4Q3Q A;  1WVA A;  3MMR A;  4ITY A;  3SL1 A;  4RHI A;  4RHQ A;  4RHL A;  3GMZ A;  4GSZ A;  1TBL A;  1D3V A;  3TF3 A;  1WOH A;  2PHO A;  4Q3T A;  4GWD A;  2EF4 A;  1T4P A;  1T5G A;  1HQ5 A;  3PZL A;  1GQ7 A;  2A0M A;  1P8M A;  4GWC A;  4IU4 A;  4RHJ A;  4MYK A;  3LHL A;  3MFV A;  3E6V A;  4G3H A;  4IU1 A;  1TA1 A;  4IXU A;  4IXV A;  3THE A;  1RLA A;  2EIV A;  3SL0 A;  1CEV A;  3LP4 A;  3NIP A;  1WVB A;  4FCK A;  4MYF A;  1T4S A;  4HZE A;  5CEV A;  4FCI A;  4RLA A;  1WOG A;  3TH7 A;  2EF5 A;  4GSV A;  1P8R A;  1GQ6 A;  3NIO A;  4IE2 A;  4MYL A;  4Q3R C;  2RLA A;  4IU5 A;  1T4T A;  3SJT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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