4GWDA

Crystal structure of the mn2+2,zn2+-human arginase i-abh complex
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Arginase-1
total genus 113
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gwdA00
4IU5A 4Q3TA 1P8MA 1P8SA 2PHOA 4MXRA 1WOHA 4RHJA 3NIQA 4MYKA 4RHLA 3E8ZA 4Q3VA 4G3HA 2EF5A 3E9BA 3E6VA 4MYFA 2AEBA 2CEVA 3F80A 4RHMA 3TF3A 4IE2A 3DJ8A 1T5FA 4HXQA 3TH7A 3MFVA 4FCKA 1GQ6A 4IXUA 4Q40A 2ZAVA 4IXVA 4Q3QA 4Q3UA 1CEVA 3SKKA 2RLAA 4IE3A 4GSVA 1ZPGA 1T4RA 4IE1A 3NIOA 4Q3RC 4RHKA 3LHLA 1HQFA 1RLAA 4IU1A 1T4TA 1XFKA 4ITYA 3PZLA 1P8OA 4IU4A 3M1RA 4Q42A 1TA1A 2PHAA 3MMRA 3SL1A 3GN0A 1ZPEA 1WVBA 3KV2A 4CEVA 4Q3PA 3E6KA 1HQXA 1P8QA 3MFWA 4I06A 3NIPA 1TBLA 4IU0A 4GWCA 1PQ3A 4HWWA 1TBHA 3RLAA 2A0MA 4FCIA 3LP4A 4MYLA 1T4PA 1P8RA 3E8QA 1HQ5A 4RLAA 3CEVA 3GMZA 2PLLA 4Q41A 4GSZA 1GQ7A 3SJTA 1R1OA 1P8NA 5RLAA 5HJAA 1P8PA 1WOIA 4RHQA 1T4SA 4Q3SA 1WOGA 4GWDA 1WVAA 3THJA 4RHIA 4GSMA 2EF4A 3MJLA 3LP7A 1HQHA 5CEVA 3THHA 1TBJA 1D3VA 4HZEA 1T5GA 5HJ9A 4MYNA 4Q3RA 4DZ4A 2EIVA 1HQGA 3SL0A 3THEA
chains in the Genus database with same CATH superfamily
4IU5A 4Q3TA 1P8MA 1P8SA 2PHOA 4MXRA 2VQMA 5G0XA 1WOHA 4RHJA 5THTA 3NIQA 4MYKA 4RHLA 1C3RA 3E8ZA 4QA0A 4Q3VA 4G3HA 2EF5A 3MZ4A 4BZ8A 2VCGA 3E9BA 3E6VA 4MYFA 5LI3A 4RN0A 2AEBA 2CEVA 3F80A 4RHMA 3TF3A 1W22A 4RN2A 5THUA 3C0YA 1ZZ3A 5G17A 5EEKA 4IE2A 1T69A 5G0YA 1ZZ0A 3DJ8A 4LY1A 1T5FA 3EWFA 4HXQA 3F07A 4ZUPA 3TH7A 3MFVA 5EFBD 5ICNB 1GQ6A 4FCKA 4IXUA 4QA6A 4Q40A 3EZPA 1C3SA 5EFHA 2ZAVA 5EEMA 5FCWA 1T64A 1ZZ1A 4IXVA 5D1CA 3C0ZA 4Q3QA 3EZTA 2VQJA 5G13A 5EFJD 4Q3UA 5IX0A 1CEVA 5G1BA 3SKKA 2RLAA 5G11A 4IE3A 3MZ3A 4GSVA 1ZPGA 1T4RA 5G1CA 4IE1A 2V5XA 3NIOA 5EENA 4Q3RC 4RHKA 2GH6A 3Q9BA 3LHLA 1HQFA 4ZUMA 1RLAA 3F0RA 4IU1A 4QA3A 1T4TA 4CBYA 1XFKA 4ITYA 5G0JA 5EEFA 3PZLA 1P8OA 4IU4A 3M1RA 3C10A 4QA1A 4ZURA 4Q42A 3SFHA 1TA1A 5JI5A 2PHAA 3MMRA 3SL1A 1ZPEA 1WVBA 3GN0A 3KV2A 5EF8A 3RQDA 4CBTA 4CEVA 1T67A 4Q3PA 3E6KA 1HQXA 5D1DA 1P8QA 3MFWA 4I06A 4QA7A 5G10A 3NIPA 4RN1A 5THVA 5EF7A 1TBLA 4IU0A 1VKGA 4GWCA 3F06A 4BZ6A 5G0GA 3MZ7A 1PQ3A 4HWWA 1TBHA 5EFKB 3RLAA 3Q9CA 2A0MA 2VQVA 4FCIA 5THSA 3LP4A 3MENA 4MYLA 1T4PA 1P8RA 3E8QA 5EFGA 4ZUNA 5FUEA 4QA4A 5D1BA 2VQOA 5G0HA 3ZNSA 1C3PA 1HQ5A 5DC7A 3Q9FA 4RLAA 3CEVA 3GMZA 2PLLA 4Q41A 3MAXA 4GSZA 1GQ7A 3SJTA 4A69A 1R1OA 1P8NA 5RLAA 5HJAA 1P8PA 1WOIA 5G1AA 4BZ5A 4ZUOA 4RHQA 1T4SA 4LXZA 2VQQA 4Q3SA 4QA2A 5DC5A 3SL0A 5IWGA 1WOGA 4GWDA 1WVAA 3THJA 2VQWG 4RHIA 5DC6A 4GSMA 3EW8A 2EF4A 3MZ6A 3ZNRA 4BZ9A 5DC8A 4ZUQA 3MJLA 3LP7A 1HQHA 5G3WA 5G0IA 2V5WA 3SFFA 5CEVA 4BZ7A 5EEIA 3THHA 4BKXB 5BWZA 1TBJA 1D3VA 4HZEA 1T5GA 5HJ9A 5A2SA 4MYNA 4Q3RA 4DZ4A 4QA5A 3Q9EA 5EFNA 2EIVA 4CQFA 1HQGA 5G12A 3THEA
chains in the Genus database with same CATH topology
4IU5A 4Q3TA 1P8MA 1P8SA 2PHOA 4MXRA 1WOHA 4RHJA 3NIQA 4MYKA 4RHLA 3E8ZA 4Q3VA 4G3HA 2EF5A 3E9BA 3E6VA 4MYFA 2AEBA 2CEVA 3F80A 4RHMA 3TF3A 4IE2A 3DJ8A 1T5FA 4HXQA 3TH7A 3MFVA 4FCKA 1GQ6A 4IXUA 4Q40A 2ZAVA 4IXVA 4Q3QA 4Q3UA 1CEVA 3SKKA 2RLAA 4IE3A 4GSVA 1ZPGA 1T4RA 4IE1A 3NIOA 4Q3RC 4RHKA 3LHLA 1HQFA 1RLAA 4IU1A 1T4TA 1XFKA 4ITYA 3PZLA 1P8OA 4IU4A 3M1RA 4Q42A 1TA1A 2PHAA 3MMRA 3SL1A 3GN0A 1ZPEA 1WVBA 3KV2A 4CEVA 4Q3PA 3E6KA 1HQXA 1P8QA 3MFWA 4I06A 3NIPA 1TBLA 4IU0A 4GWCA 1PQ3A 4HWWA 1TBHA 3RLAA 2A0MA 4FCIA 3LP4A 4MYLA 1T4PA 1P8RA 3E8QA 1HQ5A 4RLAA 3CEVA 3GMZA 2PLLA 4Q41A 4GSZA 1GQ7A 3SJTA 1R1OA 1P8NA 5RLAA 5HJAA 1P8PA 1WOIA 4RHQA 1T4SA 4Q3SA 1WOGA 4GWDA 1WVAA 3THJA 4RHIA 4GSMA 2EF4A 3MJLA 3LP7A 1HQHA 5CEVA 3THHA 1TBJA 1D3VA 4HZEA 1T5GA 5HJ9A 4MYNA 4Q3RA 4DZ4A 2EIVA 1HQGA 3SL0A 3THEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IU5 A;  4Q3T A;  1P8M A;  1P8S A;  2PHO A;  4MXR A;  1WOH A;  4RHJ A;  3NIQ A;  4MYK A;  4RHL A;  3E8Z A;  4Q3V A;  4G3H A;  2EF5 A;  3E9B A;  3E6V A;  4MYF A;  2AEB A;  2CEV A;  3F80 A;  4RHM A;  3TF3 A;  4IE2 A;  3DJ8 A;  1T5F A;  4HXQ A;  3TH7 A;  3MFV A;  4FCK A;  1GQ6 A;  4IXU A;  4Q40 A;  2ZAV A;  4IXV A;  4Q3Q A;  4Q3U A;  1CEV A;  3SKK A;  2RLA A;  4IE3 A;  4GSV A;  1ZPG A;  1T4R A;  4IE1 A;  3NIO A;  4Q3R C;  4RHK A;  3LHL A;  1HQF A;  1RLA A;  4IU1 A;  1T4T A;  1XFK A;  4ITY A;  3PZL A;  1P8O A;  4IU4 A;  3M1R A;  4Q42 A;  1TA1 A;  2PHA A;  3MMR A;  3SL1 A;  3GN0 A;  1ZPE A;  1WVB A;  3KV2 A;  4CEV A;  4Q3P A;  3E6K A;  1HQX A;  1P8Q A;  3MFW A;  4I06 A;  3NIP A;  1TBL A;  4IU0 A;  4GWC A;  1PQ3 A;  4HWW A;  1TBH A;  3RLA A;  2A0M A;  4FCI A;  3LP4 A;  4MYL A;  1T4P A;  1P8R A;  3E8Q A;  1HQ5 A;  4RLA A;  3CEV A;  3GMZ A;  2PLL A;  4Q41 A;  4GSZ A;  1GQ7 A;  3SJT A;  1R1O A;  1P8N A;  5RLA A;  5HJA A;  1P8P A;  1WOI A;  4RHQ A;  1T4S A;  4Q3S A;  1WOG A;  4GWD A;  1WVA A;  3THJ A;  4RHI A;  4GSM A;  2EF4 A;  3MJL A;  3LP7 A;  1HQH A;  5CEV A;  3THH A;  1TBJ A;  1D3V A;  4HZE A;  1T5G A;  5HJ9 A;  4MYN A;  4Q3R A;  4DZ4 A;  2EIV A;  1HQG A;  3SL0 A;  3THE A; 
#chains in the Genus database with same CATH topology
 4IU5 A;  4Q3T A;  1P8M A;  1P8S A;  2PHO A;  4MXR A;  2VQM A;  5G0X A;  1WOH A;  4RHJ A;  5THT A;  3NIQ A;  4MYK A;  4RHL A;  1C3R A;  3E8Z A;  4QA0 A;  4Q3V A;  4G3H A;  2EF5 A;  3MZ4 A;  4BZ8 A;  2VCG A;  3E9B A;  3E6V A;  4MYF A;  5LI3 A;  4RN0 A;  2AEB A;  2CEV A;  3F80 A;  4RHM A;  3TF3 A;  1W22 A;  4RN2 A;  5THU A;  3C0Y A;  1ZZ3 A;  5G17 A;  5EEK A;  4IE2 A;  1T69 A;  5G0Y A;  1ZZ0 A;  3DJ8 A;  4LY1 A;  1T5F A;  3EWF A;  4HXQ A;  3F07 A;  4ZUP A;  3TH7 A;  3MFV A;  5EFB D;  5ICN B;  1GQ6 A;  4FCK A;  4IXU A;  4QA6 A;  4Q40 A;  3EZP A;  1C3S A;  5EFH A;  2ZAV A;  5EEM A;  5FCW A;  1T64 A;  1ZZ1 A;  4IXV A;  5D1C A;  3C0Z A;  4Q3Q A;  3EZT A;  2VQJ A;  5G13 A;  5EFJ D;  4Q3U A;  5IX0 A;  1CEV A;  5G1B A;  3SKK A;  2RLA A;  5G11 A;  4IE3 A;  3MZ3 A;  4GSV A;  1ZPG A;  1T4R A;  5G1C A;  4IE1 A;  2V5X A;  3NIO A;  5EEN A;  4Q3R C;  4RHK A;  2GH6 A;  3Q9B A;  3LHL A;  1HQF A;  4ZUM A;  1RLA A;  3F0R A;  4IU1 A;  4QA3 A;  1T4T A;  4CBY A;  1XFK A;  4ITY A;  5G0J A;  5EEF A;  3PZL A;  1P8O A;  4IU4 A;  3M1R A;  3C10 A;  4QA1 A;  4ZUR A;  4Q42 A;  3SFH A;  1TA1 A;  5JI5 A;  2PHA A;  3MMR A;  3SL1 A;  1ZPE A;  1WVB A;  3GN0 A;  3KV2 A;  5EF8 A;  3RQD A;  4CBT A;  4CEV A;  1T67 A;  4Q3P A;  3E6K A;  1HQX A;  5D1D A;  1P8Q A;  3MFW A;  4I06 A;  4QA7 A;  5G10 A;  3NIP A;  4RN1 A;  5THV A;  5EF7 A;  1TBL A;  4IU0 A;  1VKG A;  4GWC A;  3F06 A;  4BZ6 A;  5G0G A;  3MZ7 A;  1PQ3 A;  4HWW A;  1TBH A;  5EFK B;  3RLA A;  3Q9C A;  2A0M A;  2VQV A;  4FCI A;  5THS A;  3LP4 A;  3MEN A;  4MYL A;  1T4P A;  1P8R A;  3E8Q A;  5EFG A;  4ZUN A;  5FUE A;  4QA4 A;  5D1B A;  2VQO A;  5G0H A;  3ZNS A;  1C3P A;  1HQ5 A;  5DC7 A;  3Q9F A;  4RLA A;  3CEV A;  3GMZ A;  2PLL A;  4Q41 A;  3MAX A;  4GSZ A;  1GQ7 A;  3SJT A;  4A69 A;  1R1O A;  1P8N A;  5RLA A;  5HJA A;  1P8P A;  1WOI A;  5G1A A;  4BZ5 A;  4ZUO A;  4RHQ A;  1T4S A;  4LXZ A;  2VQQ A;  4Q3S A;  4QA2 A;  5DC5 A;  3SL0 A;  5IWG A;  1WOG A;  4GWD A;  1WVA A;  3THJ A;  2VQW G;  4RHI A;  5DC6 A;  4GSM A;  3EW8 A;  2EF4 A;  3MZ6 A;  3ZNR A;  4BZ9 A;  5DC8 A;  4ZUQ A;  3MJL A;  3LP7 A;  1HQH A;  5G3W A;  5G0I A;  2V5W A;  3SFF A;  5CEV A;  4BZ7 A;  5EEI A;  3THH A;  4BKX B;  5BWZ A;  1TBJ A;  1D3V A;  4HZE A;  1T5G A;  5HJ9 A;  5A2S A;  4MYN A;  4Q3R A;  4DZ4 A;  4QA5 A;  3Q9E A;  5EFN A;  2EIV A;  4CQF A;  1HQG A;  5G12 A;  3THE A; 
#chains in the Genus database with same CATH homology
 4IU5 A;  4Q3T A;  1P8M A;  1P8S A;  2PHO A;  4MXR A;  1WOH A;  4RHJ A;  3NIQ A;  4MYK A;  4RHL A;  3E8Z A;  4Q3V A;  4G3H A;  2EF5 A;  3E9B A;  3E6V A;  4MYF A;  2AEB A;  2CEV A;  3F80 A;  4RHM A;  3TF3 A;  4IE2 A;  3DJ8 A;  1T5F A;  4HXQ A;  3TH7 A;  3MFV A;  4FCK A;  1GQ6 A;  4IXU A;  4Q40 A;  2ZAV A;  4IXV A;  4Q3Q A;  4Q3U A;  1CEV A;  3SKK A;  2RLA A;  4IE3 A;  4GSV A;  1ZPG A;  1T4R A;  4IE1 A;  3NIO A;  4Q3R C;  4RHK A;  3LHL A;  1HQF A;  1RLA A;  4IU1 A;  1T4T A;  1XFK A;  4ITY A;  3PZL A;  1P8O A;  4IU4 A;  3M1R A;  4Q42 A;  1TA1 A;  2PHA A;  3MMR A;  3SL1 A;  3GN0 A;  1ZPE A;  1WVB A;  3KV2 A;  4CEV A;  4Q3P A;  3E6K A;  1HQX A;  1P8Q A;  3MFW A;  4I06 A;  3NIP A;  1TBL A;  4IU0 A;  4GWC A;  1PQ3 A;  4HWW A;  1TBH A;  3RLA A;  2A0M A;  4FCI A;  3LP4 A;  4MYL A;  1T4P A;  1P8R A;  3E8Q A;  1HQ5 A;  4RLA A;  3CEV A;  3GMZ A;  2PLL A;  4Q41 A;  4GSZ A;  1GQ7 A;  3SJT A;  1R1O A;  1P8N A;  5RLA A;  5HJA A;  1P8P A;  1WOI A;  4RHQ A;  1T4S A;  4Q3S A;  1WOG A;  4GWD A;  1WVA A;  3THJ A;  4RHI A;  4GSM A;  2EF4 A;  3MJL A;  3LP7 A;  1HQH A;  5CEV A;  3THH A;  1TBJ A;  1D3V A;  4HZE A;  1T5G A;  5HJ9 A;  4MYN A;  4Q3R A;  4DZ4 A;  2EIV A;  1HQG A;  3SL0 A;  3THE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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