4Q3PA

Crystal structure of schistosoma mansoni arginase
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
345
structure length
336
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Arginase
total genus 125
structure length 336
sequence length 345
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q3pA00
1P8MA 4IU4A 2RLAA 4IE2A 3SKKA 3SL0A 1TA1A 1GQ6A 4RHJA 1GQ7A 1P8RA 2PHOA 1TBJA 3LHLA 4IE3A 4Q40A 3E6VA 4Q3PA 3E8ZA 4Q3UA 3THEA 1RLAA 1R1OA 2A0MA 4IU5A 4Q3QA 1WOGA 3SL1A 4Q41A 4Q3RA 3E9BA 5CEVA 4G3HA 3MMRA 2ZAVA 3F80A 4RHQA 4FCKA 4IU1A 3M1RA 4HXQA 1D3VA 1P8QA 1T4TA 1T5FA 1ZPGA 3THJA 4I06A 3CEVA 4Q42A 3MJLA 4GSVA 3NIOA 4GWCA 3TF3A 3THHA 3TH7A 4GWDA 2EF4A 4ITYA 1TBHA 4Q3TA 1HQHA 4HWWA 3DJ8A 1PQ3A 1WVAA 3PZLA 4IE1A 3MFWA 2EIVA 2AEBA 4MXRA 4IXVA 2EF5A 3NIPA 3SJTA 1XFKA 4HZEA 4MYLA 1T4PA 4IU0A 4RHMA 2PHAA 1P8PA 1CEVA 3LP7A 4CEVA 3LP4A 1HQFA 5HJAA 5RLAA 3E6KA 4IXUA 3NIQA 4GSZA 4Q3RC 4RHKA 4RHLA 4FCIA 1WOIA 1P8NA 2CEVA 4DZ4A 1P8SA 1WVBA 4MYFA 4RHIA 1T5GA 3E8QA 4Q3SA 1P8OA 5HJ9A 3KV2A 2PLLA 4MYNA 1HQXA 3GMZA 3RLAA 1T4SA 1T4RA 4GSMA 1TBLA 3MFVA 4Q3VA 4RLAA 1HQGA 4MYKA 1WOHA 1ZPEA 1HQ5A 3GN0A
chains in the Genus database with same CATH superfamily
1P8MA 4IU4A 2RLAA 4QA6A 1ZZ1A 2V5WA 4IE2A 4BZ9A 3Q9FA 3SL0A 5DC8A 5EFBD 2VQOA 3SKKA 1TA1A 1GQ6A 4RHJA 1GQ7A 4BZ7A 1P8RA 3MZ6A 2PHOA 1TBJA 3LHLA 4QA3A 4BZ6A 4BZ8A 3RQDA 4QA5A 4RN0A 4IE3A 4ZUPA 4Q40A 1ZZ3A 3E6VA 4Q3PA 4RN1A 3E8ZA 4Q3UA 5DC7A 1RLAA 1R1OA 2A0MA 5FUEA 4IU5A 5G1CA 4Q3QA 5THSA 3THEA 2VCGA 4ZUMA 5G0IA 1WOGA 3C0YA 4QA1A 3SL1A 4CBYA 4Q3RA 3E9BA 4Q41A 5CEVA 4G3HA 3MMRA 2ZAVA 3F80A 5EEKA 4CQFA 4RHQA 5IX0A 4FCKA 5G0YA 5JI5A 4IU1A 4LXZA 5G0HA 2VQQA 3M1RA 4HXQA 1D3VA 1P8QA 1T64A 1T4TA 1T5FA 3MENA 1ZPGA 3THJA 4I06A 3CEVA 3F07A 5EF8A 4Q42A 3MJLA 4GSVA 5THTA 3NIOA 4GWCA 5D1DA 2VQVA 2VQMA 3TF3A 3THHA 1VKGA 5EEIA 1ZZ0A 3C0ZA 4GWDA 2EF4A 4ITYA 1TBHA 4Q3TA 5G13A 3TH7A 5G1BA 5THVA 3EZPA 1HQHA 3MZ7A 3ZNRA 4HWWA 3DJ8A 1PQ3A 1WVAA 3PZLA 4IE1A 5EEMA 3SFHA 1T67A 3MFWA 2EIVA 3Q9CA 2AEBA 3SFFA 3EZTA 4MXRA 4IXVA 5EF7A 4BKXB 2EF5A 3NIPA 3SJTA 1XFKA 3C10A 4HZEA 5DC5A 5EFJD 4MYLA 2VQJA 1T4PA 4IU0A 5G11A 4RN2A 2GH6A 5G3WA 4RHMA 5G0GA 2PHAA 2VQWG 5LI3A 1P8PA 1CEVA 3LP7A 4CEVA 3LP4A 5A2SA 1HQFA 4ZUOA 5HJAA 5RLAA 3EWFA 3EW8A 5FCWA 5IWGA 2V5XA 5EFNA 4ZURA 4LY1A 3E6KA 3F0RA 3Q9EA 4IXUA 3NIQA 4GSZA 4Q3RC 4QA4A 4RHKA 5D1BA 4ZUQA 4RHLA 4FCIA 1WOIA 1C3PA 1P8NA 2CEVA 1P8SA 4DZ4A 4CBTA 1WVBA 4MYFA 4RHIA 5G1AA 5G0JA 5D1CA 1T5GA 4ZUNA 5THUA 3E8QA 5G17A 5ICNB 4Q3SA 1P8OA 3MAXA 5HJ9A 3KV2A 2PLLA 5EFKB 5EFGA 5G12A 4MYNA 4A69A 1C3RA 1HQXA 3GMZA 3F06A 1C3SA 4BZ5A 5EFHA 3RLAA 5BWZA 1T4SA 5EEFA 1T4RA 3ZNSA 4GSMA 1TBLA 4QA2A 3MFVA 4Q3VA 1W22A 4RLAA 5G10A 3MZ4A 1HQGA 3Q9BA 4MYKA 1WOHA 5DC6A 3MZ3A 4QA7A 5G0XA 4QA0A 1ZPEA 5EENA 1HQ5A 3GN0A 1T69A
chains in the Genus database with same CATH topology
1P8MA 4IU4A 2RLAA 4IE2A 3SKKA 3SL0A 1TA1A 1GQ6A 4RHJA 1GQ7A 1P8RA 2PHOA 1TBJA 3LHLA 4IE3A 4Q40A 3E6VA 4Q3PA 3E8ZA 4Q3UA 3THEA 1RLAA 1R1OA 2A0MA 4IU5A 4Q3QA 1WOGA 3SL1A 4Q41A 4Q3RA 3E9BA 5CEVA 4G3HA 3MMRA 2ZAVA 3F80A 4RHQA 4FCKA 4IU1A 3M1RA 4HXQA 1D3VA 1P8QA 1T4TA 1T5FA 1ZPGA 3THJA 4I06A 3CEVA 4Q42A 3MJLA 4GSVA 3NIOA 4GWCA 3TF3A 3THHA 3TH7A 4GWDA 2EF4A 4ITYA 1TBHA 4Q3TA 1HQHA 4HWWA 3DJ8A 1PQ3A 1WVAA 3PZLA 4IE1A 3MFWA 2EIVA 2AEBA 4MXRA 4IXVA 2EF5A 3NIPA 3SJTA 1XFKA 4HZEA 4MYLA 1T4PA 4IU0A 4RHMA 2PHAA 1P8PA 1CEVA 3LP7A 4CEVA 3LP4A 1HQFA 5HJAA 5RLAA 3E6KA 4IXUA 3NIQA 4GSZA 4Q3RC 4RHKA 4RHLA 4FCIA 1WOIA 1P8NA 2CEVA 4DZ4A 1P8SA 1WVBA 4MYFA 4RHIA 1T5GA 3E8QA 4Q3SA 1P8OA 5HJ9A 3KV2A 2PLLA 4MYNA 1HQXA 3GMZA 3RLAA 1T4SA 1T4RA 4GSMA 1TBLA 3MFVA 4Q3VA 4RLAA 1HQGA 4MYKA 1WOHA 1ZPEA 1HQ5A 3GN0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8M A;  4IU4 A;  2RLA A;  4IE2 A;  3SKK A;  3SL0 A;  1TA1 A;  1GQ6 A;  4RHJ A;  1GQ7 A;  1P8R A;  2PHO A;  1TBJ A;  3LHL A;  4IE3 A;  4Q40 A;  3E6V A;  4Q3P A;  3E8Z A;  4Q3U A;  3THE A;  1RLA A;  1R1O A;  2A0M A;  4IU5 A;  4Q3Q A;  1WOG A;  3SL1 A;  4Q41 A;  4Q3R A;  3E9B A;  5CEV A;  4G3H A;  3MMR A;  2ZAV A;  3F80 A;  4RHQ A;  4FCK A;  4IU1 A;  3M1R A;  4HXQ A;  1D3V A;  1P8Q A;  1T4T A;  1T5F A;  1ZPG A;  3THJ A;  4I06 A;  3CEV A;  4Q42 A;  3MJL A;  4GSV A;  3NIO A;  4GWC A;  3TF3 A;  3THH A;  3TH7 A;  4GWD A;  2EF4 A;  4ITY A;  1TBH A;  4Q3T A;  1HQH A;  4HWW A;  3DJ8 A;  1PQ3 A;  1WVA A;  3PZL A;  4IE1 A;  3MFW A;  2EIV A;  2AEB A;  4MXR A;  4IXV A;  2EF5 A;  3NIP A;  3SJT A;  1XFK A;  4HZE A;  4MYL A;  1T4P A;  4IU0 A;  4RHM A;  2PHA A;  1P8P A;  1CEV A;  3LP7 A;  4CEV A;  3LP4 A;  1HQF A;  5HJA A;  5RLA A;  3E6K A;  4IXU A;  3NIQ A;  4GSZ A;  4Q3R C;  4RHK A;  4RHL A;  4FCI A;  1WOI A;  1P8N A;  2CEV A;  4DZ4 A;  1P8S A;  1WVB A;  4MYF A;  4RHI A;  1T5G A;  3E8Q A;  4Q3S A;  1P8O A;  5HJ9 A;  3KV2 A;  2PLL A;  4MYN A;  1HQX A;  3GMZ A;  3RLA A;  1T4S A;  1T4R A;  4GSM A;  1TBL A;  3MFV A;  4Q3V A;  4RLA A;  1HQG A;  4MYK A;  1WOH A;  1ZPE A;  1HQ5 A;  3GN0 A; 
#chains in the Genus database with same CATH topology
 1P8M A;  4IU4 A;  2RLA A;  4QA6 A;  1ZZ1 A;  2V5W A;  4IE2 A;  4BZ9 A;  3Q9F A;  3SL0 A;  5DC8 A;  5EFB D;  2VQO A;  3SKK A;  1TA1 A;  1GQ6 A;  4RHJ A;  1GQ7 A;  4BZ7 A;  1P8R A;  3MZ6 A;  2PHO A;  1TBJ A;  3LHL A;  4QA3 A;  4BZ6 A;  4BZ8 A;  3RQD A;  4QA5 A;  4RN0 A;  4IE3 A;  4ZUP A;  4Q40 A;  1ZZ3 A;  3E6V A;  4Q3P A;  4RN1 A;  3E8Z A;  4Q3U A;  5DC7 A;  1RLA A;  1R1O A;  2A0M A;  5FUE A;  4IU5 A;  5G1C A;  4Q3Q A;  5THS A;  3THE A;  2VCG A;  4ZUM A;  5G0I A;  1WOG A;  3C0Y A;  4QA1 A;  3SL1 A;  4CBY A;  4Q3R A;  3E9B A;  4Q41 A;  5CEV A;  4G3H A;  3MMR A;  2ZAV A;  3F80 A;  5EEK A;  4CQF A;  4RHQ A;  5IX0 A;  4FCK A;  5G0Y A;  5JI5 A;  4IU1 A;  4LXZ A;  5G0H A;  2VQQ A;  3M1R A;  4HXQ A;  1D3V A;  1P8Q A;  1T64 A;  1T4T A;  1T5F A;  3MEN A;  1ZPG A;  3THJ A;  4I06 A;  3CEV A;  3F07 A;  5EF8 A;  4Q42 A;  3MJL A;  4GSV A;  5THT A;  3NIO A;  4GWC A;  5D1D A;  2VQV A;  2VQM A;  3TF3 A;  3THH A;  1VKG A;  5EEI A;  1ZZ0 A;  3C0Z A;  4GWD A;  2EF4 A;  4ITY A;  1TBH A;  4Q3T A;  5G13 A;  3TH7 A;  5G1B A;  5THV A;  3EZP A;  1HQH A;  3MZ7 A;  3ZNR A;  4HWW A;  3DJ8 A;  1PQ3 A;  1WVA A;  3PZL A;  4IE1 A;  5EEM A;  3SFH A;  1T67 A;  3MFW A;  2EIV A;  3Q9C A;  2AEB A;  3SFF A;  3EZT A;  4MXR A;  4IXV A;  5EF7 A;  4BKX B;  2EF5 A;  3NIP A;  3SJT A;  1XFK A;  3C10 A;  4HZE A;  5DC5 A;  5EFJ D;  4MYL A;  2VQJ A;  1T4P A;  4IU0 A;  5G11 A;  4RN2 A;  2GH6 A;  5G3W A;  4RHM A;  5G0G A;  2PHA A;  2VQW G;  5LI3 A;  1P8P A;  1CEV A;  3LP7 A;  4CEV A;  3LP4 A;  5A2S A;  1HQF A;  4ZUO A;  5HJA A;  5RLA A;  3EWF A;  3EW8 A;  5FCW A;  5IWG A;  2V5X A;  5EFN A;  4ZUR A;  4LY1 A;  3E6K A;  3F0R A;  3Q9E A;  4IXU A;  3NIQ A;  4GSZ A;  4Q3R C;  4QA4 A;  4RHK A;  5D1B A;  4ZUQ A;  4RHL A;  4FCI A;  1WOI A;  1C3P A;  1P8N A;  2CEV A;  1P8S A;  4DZ4 A;  4CBT A;  1WVB A;  4MYF A;  4RHI A;  5G1A A;  5G0J A;  5D1C A;  1T5G A;  4ZUN A;  5THU A;  3E8Q A;  5G17 A;  5ICN B;  4Q3S A;  1P8O A;  3MAX A;  5HJ9 A;  3KV2 A;  2PLL A;  5EFK B;  5EFG A;  5G12 A;  4MYN A;  4A69 A;  1C3R A;  1HQX A;  3GMZ A;  3F06 A;  1C3S A;  4BZ5 A;  5EFH A;  3RLA A;  5BWZ A;  1T4S A;  5EEF A;  1T4R A;  3ZNS A;  4GSM A;  1TBL A;  4QA2 A;  3MFV A;  4Q3V A;  1W22 A;  4RLA A;  5G10 A;  3MZ4 A;  1HQG A;  3Q9B A;  4MYK A;  1WOH A;  5DC6 A;  3MZ3 A;  4QA7 A;  5G0X A;  4QA0 A;  1ZPE A;  5EEN A;  1HQ5 A;  3GN0 A;  1T69 A; 
#chains in the Genus database with same CATH homology
 1P8M A;  4IU4 A;  2RLA A;  4IE2 A;  3SKK A;  3SL0 A;  1TA1 A;  1GQ6 A;  4RHJ A;  1GQ7 A;  1P8R A;  2PHO A;  1TBJ A;  3LHL A;  4IE3 A;  4Q40 A;  3E6V A;  4Q3P A;  3E8Z A;  4Q3U A;  3THE A;  1RLA A;  1R1O A;  2A0M A;  4IU5 A;  4Q3Q A;  1WOG A;  3SL1 A;  4Q41 A;  4Q3R A;  3E9B A;  5CEV A;  4G3H A;  3MMR A;  2ZAV A;  3F80 A;  4RHQ A;  4FCK A;  4IU1 A;  3M1R A;  4HXQ A;  1D3V A;  1P8Q A;  1T4T A;  1T5F A;  1ZPG A;  3THJ A;  4I06 A;  3CEV A;  4Q42 A;  3MJL A;  4GSV A;  3NIO A;  4GWC A;  3TF3 A;  3THH A;  3TH7 A;  4GWD A;  2EF4 A;  4ITY A;  1TBH A;  4Q3T A;  1HQH A;  4HWW A;  3DJ8 A;  1PQ3 A;  1WVA A;  3PZL A;  4IE1 A;  3MFW A;  2EIV A;  2AEB A;  4MXR A;  4IXV A;  2EF5 A;  3NIP A;  3SJT A;  1XFK A;  4HZE A;  4MYL A;  1T4P A;  4IU0 A;  4RHM A;  2PHA A;  1P8P A;  1CEV A;  3LP7 A;  4CEV A;  3LP4 A;  1HQF A;  5HJA A;  5RLA A;  3E6K A;  4IXU A;  3NIQ A;  4GSZ A;  4Q3R C;  4RHK A;  4RHL A;  4FCI A;  1WOI A;  1P8N A;  2CEV A;  4DZ4 A;  1P8S A;  1WVB A;  4MYF A;  4RHI A;  1T5G A;  3E8Q A;  4Q3S A;  1P8O A;  5HJ9 A;  3KV2 A;  2PLL A;  4MYN A;  1HQX A;  3GMZ A;  3RLA A;  1T4S A;  1T4R A;  4GSM A;  1TBL A;  3MFV A;  4Q3V A;  4RLA A;  1HQG A;  4MYK A;  1WOH A;  1ZPE A;  1HQ5 A;  3GN0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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