4Q42A

Crystal structure of schistosoma mansoni arginase in complex with l-ornithine
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
345
structure length
336
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Arginase
total genus 129
structure length 336
sequence length 345
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q42A00
4Q3RA 4I06A 4GWCA 1GQ6A 1TBHA 4RHIA 4IU0A 1GQ7A 4RHMA 3M1RA 3E8ZA 4G3HA 3NIQA 2RLAA 2EF5A 1HQXA 4RHLA 4GSMA 3MMRA 1HQHA 1P8NA 4Q3SA 3CEVA 3F80A 4ITYA 3LP4A 2PLLA 1TBLA 4Q40A 4RHQA 4Q3UA 4IXVA 4Q3RC 1T5FA 4Q3TA 4RHJA 3RLAA 1XFKA 4Q41A 4MXRA 4Q3VA 3TH7A 3SL1A 1P8SA 4HWWA 4FCKA 2CEVA 3GN0A 3THJA 1R1OA 4MYLA 4Q3PA 4IU5A 4MYFA 4GSZA 4IE3A 3E8QA 3PZLA 3SL0A 4IE1A 1P8MA 3MFVA 4IXUA 1ZPEA 1P8QA 1WOIA 4HXQA 3TF3A 2EIVA 5HJAA 1WOHA 1HQ5A 1TA1A 2EF4A 4MYKA 1HQGA 1D3VA 4Q3QA 4IU4A 4GWDA 1WOGA 1WVBA 3SJTA 4DZ4A 4IE2A 3LHLA 3LP7A 3THHA 1P8OA 5HJ9A 3DJ8A 4Q42A 1TBJA 4GSVA 4MYNA 3GMZA 1WVAA 3MFWA 3E6VA 3NIOA 3KV2A 5CEVA 3NIPA 2AEBA 1ZPGA 3E6KA 1T4SA 4RHKA 1T4RA 2A0MA 3THEA 3E9BA 2PHOA 1PQ3A 1CEVA 1T4TA 1T5GA 3SKKA 1T4PA 5RLAA 4CEVA 1HQFA 2ZAVA 3MJLA 4IU1A 1P8RA 4FCIA 4HZEA 2PHAA 1RLAA 1P8PA 4RLAA
chains in the Genus database with same CATH superfamily
5G12A 4ZUOA 4Q3RA 5EF8A 4I06A 4GWCA 3SFHA 1GQ6A 2VCGA 1TBHA 3Q9CA 5D1CA 3MZ7A 2GH6A 4RHIA 4IU0A 4RN2A 1GQ7A 5EFHA 5G3WA 4RHMA 2V5XA 5G1AA 3M1RA 4BKXB 3E8ZA 4G3HA 5A2SA 3MZ3A 3NIQA 5THVA 2RLAA 2EF5A 1HQXA 2VQJA 4GSMA 4RHLA 3MMRA 1HQHA 5G11A 1P8NA 2VQMA 1T64A 5G0YA 4BZ5A 3RQDA 4Q3SA 3CEVA 3F80A 2VQWG 4ITYA 3C0ZA 4RN1A 5G13A 3LP4A 2PLLA 1TBLA 4Q40A 4RHQA 5DC7A 4Q3UA 4IXVA 5FUEA 2VQVA 4Q3RC 1T5FA 4Q3TA 4RHJA 5D1DA 5EFBD 3RLAA 5EFJD 4BZ8A 1XFKA 3F07A 4Q41A 5G1CA 5IX0A 4MXRA 4Q3VA 3TH7A 3SL1A 5DC8A 1P8SA 4HWWA 4FCKA 5EEMA 5G10A 2CEVA 3GN0A 5G1BA 3THJA 5EEFA 3C10A 3MENA 1R1OA 4MYLA 5THUA 4Q3PA 1T67A 4RN0A 3SFFA 4IU5A 4MYFA 4ZUMA 5BWZA 3MZ6A 4GSZA 4IE3A 3E8QA 4QA3A 3PZLA 4A69A 3SL0A 4IE1A 1P8MA 3MFVA 5G0HA 4IXUA 1ZPEA 1P8QA 1WOIA 3C0YA 3EW8A 4HXQA 5FCWA 3TF3A 3MZ4A 2EIVA 5HJAA 1WOHA 3Q9FA 1W22A 1HQ5A 1TA1A 2EF4A 4MYKA 1C3RA 5JI5A 1HQGA 4LXZA 1VKGA 5D1BA 1D3VA 4Q3QA 1ZZ3A 5EF7A 1ZZ0A 4IU4A 4GWDA 4LY1A 5EFNA 1WOGA 4QA4A 1WVBA 2V5WA 3SJTA 4DZ4A 5G17A 4IE2A 3LHLA 4ZUQA 3LP7A 5EFGA 2VQOA 5EEIA 5THTA 1P8OA 5THSA 3THHA 3ZNSA 4BZ9A 5HJ9A 3DJ8A 3MAXA 3EZPA 4QA2A 4Q42A 1C3PA 1TBJA 4GSVA 3Q9BA 4MYNA 3F06A 3GMZA 5DC5A 1WVAA 5EEKA 5G0GA 3MFWA 3E6VA 3NIOA 3KV2A 5G0XA 5CEVA 3NIPA 5ICNB 2AEBA 1ZPGA 3E6KA 2VQQA 4ZUPA 4ZURA 1T4SA 4BZ7A 4RHKA 4CQFA 5DC6A 3EZTA 4ZUNA 1T4RA 2A0MA 4QA1A 3THEA 3E9BA 2PHOA 5EFKB 3EWFA 5G0IA 1PQ3A 1C3SA 5IWGA 5EENA 4CBYA 1CEVA 1T4TA 1T5GA 3SKKA 1T4PA 5RLAA 4CEVA 1HQFA 5LI3A 4BZ6A 1T69A 4QA5A 2ZAVA 5G0JA 3MJLA 4IU1A 4QA7A 3ZNRA 1P8RA 1ZZ1A 3F0RA 3Q9EA 4FCIA 4HZEA 2PHAA 4QA0A 1RLAA 4QA6A 1P8PA 4RLAA 4CBTA
chains in the Genus database with same CATH topology
4Q3RA 4I06A 4GWCA 1GQ6A 1TBHA 4RHIA 4IU0A 1GQ7A 4RHMA 3M1RA 3E8ZA 4G3HA 3NIQA 2RLAA 2EF5A 1HQXA 4RHLA 4GSMA 3MMRA 1HQHA 1P8NA 4Q3SA 3CEVA 3F80A 4ITYA 3LP4A 2PLLA 1TBLA 4Q40A 4RHQA 4Q3UA 4IXVA 4Q3RC 1T5FA 4Q3TA 4RHJA 3RLAA 1XFKA 4Q41A 4MXRA 4Q3VA 3TH7A 3SL1A 1P8SA 4HWWA 4FCKA 2CEVA 3GN0A 3THJA 1R1OA 4MYLA 4Q3PA 4IU5A 4MYFA 4GSZA 4IE3A 3E8QA 3PZLA 3SL0A 4IE1A 1P8MA 3MFVA 4IXUA 1ZPEA 1P8QA 1WOIA 4HXQA 3TF3A 2EIVA 5HJAA 1WOHA 1HQ5A 1TA1A 2EF4A 4MYKA 1HQGA 1D3VA 4Q3QA 4IU4A 4GWDA 1WOGA 1WVBA 3SJTA 4DZ4A 4IE2A 3LHLA 3LP7A 3THHA 1P8OA 5HJ9A 3DJ8A 4Q42A 1TBJA 4GSVA 4MYNA 3GMZA 1WVAA 3MFWA 3E6VA 3NIOA 3KV2A 5CEVA 3NIPA 2AEBA 1ZPGA 3E6KA 1T4SA 4RHKA 1T4RA 2A0MA 3THEA 3E9BA 2PHOA 1PQ3A 1CEVA 1T4TA 1T5GA 3SKKA 1T4PA 5RLAA 4CEVA 1HQFA 2ZAVA 3MJLA 4IU1A 1P8RA 4FCIA 4HZEA 2PHAA 1RLAA 1P8PA 4RLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Q3R A;  4I06 A;  4GWC A;  1GQ6 A;  1TBH A;  4RHI A;  4IU0 A;  1GQ7 A;  4RHM A;  3M1R A;  3E8Z A;  4G3H A;  3NIQ A;  2RLA A;  2EF5 A;  1HQX A;  4RHL A;  4GSM A;  3MMR A;  1HQH A;  1P8N A;  4Q3S A;  3CEV A;  3F80 A;  4ITY A;  3LP4 A;  2PLL A;  1TBL A;  4Q40 A;  4RHQ A;  4Q3U A;  4IXV A;  4Q3R C;  1T5F A;  4Q3T A;  4RHJ A;  3RLA A;  1XFK A;  4Q41 A;  4MXR A;  4Q3V A;  3TH7 A;  3SL1 A;  1P8S A;  4HWW A;  4FCK A;  2CEV A;  3GN0 A;  3THJ A;  1R1O A;  4MYL A;  4Q3P A;  4IU5 A;  4MYF A;  4GSZ A;  4IE3 A;  3E8Q A;  3PZL A;  3SL0 A;  4IE1 A;  1P8M A;  3MFV A;  4IXU A;  1ZPE A;  1P8Q A;  1WOI A;  4HXQ A;  3TF3 A;  2EIV A;  5HJA A;  1WOH A;  1HQ5 A;  1TA1 A;  2EF4 A;  4MYK A;  1HQG A;  1D3V A;  4Q3Q A;  4IU4 A;  4GWD A;  1WOG A;  1WVB A;  3SJT A;  4DZ4 A;  4IE2 A;  3LHL A;  3LP7 A;  3THH A;  1P8O A;  5HJ9 A;  3DJ8 A;  4Q42 A;  1TBJ A;  4GSV A;  4MYN A;  3GMZ A;  1WVA A;  3MFW A;  3E6V A;  3NIO A;  3KV2 A;  5CEV A;  3NIP A;  2AEB A;  1ZPG A;  3E6K A;  1T4S A;  4RHK A;  1T4R A;  2A0M A;  3THE A;  3E9B A;  2PHO A;  1PQ3 A;  1CEV A;  1T4T A;  1T5G A;  3SKK A;  1T4P A;  5RLA A;  4CEV A;  1HQF A;  2ZAV A;  3MJL A;  4IU1 A;  1P8R A;  4FCI A;  4HZE A;  2PHA A;  1RLA A;  1P8P A;  4RLA A; 
#chains in the Genus database with same CATH topology
 5G12 A;  4ZUO A;  4Q3R A;  5EF8 A;  4I06 A;  4GWC A;  3SFH A;  1GQ6 A;  2VCG A;  1TBH A;  3Q9C A;  5D1C A;  3MZ7 A;  2GH6 A;  4RHI A;  4IU0 A;  4RN2 A;  1GQ7 A;  5EFH A;  5G3W A;  4RHM A;  2V5X A;  5G1A A;  3M1R A;  4BKX B;  3E8Z A;  4G3H A;  5A2S A;  3MZ3 A;  3NIQ A;  5THV A;  2RLA A;  2EF5 A;  1HQX A;  2VQJ A;  4GSM A;  4RHL A;  3MMR A;  1HQH A;  5G11 A;  1P8N A;  2VQM A;  1T64 A;  5G0Y A;  4BZ5 A;  3RQD A;  4Q3S A;  3CEV A;  3F80 A;  2VQW G;  4ITY A;  3C0Z A;  4RN1 A;  5G13 A;  3LP4 A;  2PLL A;  1TBL A;  4Q40 A;  4RHQ A;  5DC7 A;  4Q3U A;  4IXV A;  5FUE A;  2VQV A;  4Q3R C;  1T5F A;  4Q3T A;  4RHJ A;  5D1D A;  5EFB D;  3RLA A;  5EFJ D;  4BZ8 A;  1XFK A;  3F07 A;  4Q41 A;  5G1C A;  5IX0 A;  4MXR A;  4Q3V A;  3TH7 A;  3SL1 A;  5DC8 A;  1P8S A;  4HWW A;  4FCK A;  5EEM A;  5G10 A;  2CEV A;  3GN0 A;  5G1B A;  3THJ A;  5EEF A;  3C10 A;  3MEN A;  1R1O A;  4MYL A;  5THU A;  4Q3P A;  1T67 A;  4RN0 A;  3SFF A;  4IU5 A;  4MYF A;  4ZUM A;  5BWZ A;  3MZ6 A;  4GSZ A;  4IE3 A;  3E8Q A;  4QA3 A;  3PZL A;  4A69 A;  3SL0 A;  4IE1 A;  1P8M A;  3MFV A;  5G0H A;  4IXU A;  1ZPE A;  1P8Q A;  1WOI A;  3C0Y A;  3EW8 A;  4HXQ A;  5FCW A;  3TF3 A;  3MZ4 A;  2EIV A;  5HJA A;  1WOH A;  3Q9F A;  1W22 A;  1HQ5 A;  1TA1 A;  2EF4 A;  4MYK A;  1C3R A;  5JI5 A;  1HQG A;  4LXZ A;  1VKG A;  5D1B A;  1D3V A;  4Q3Q A;  1ZZ3 A;  5EF7 A;  1ZZ0 A;  4IU4 A;  4GWD A;  4LY1 A;  5EFN A;  1WOG A;  4QA4 A;  1WVB A;  2V5W A;  3SJT A;  4DZ4 A;  5G17 A;  4IE2 A;  3LHL A;  4ZUQ A;  3LP7 A;  5EFG A;  2VQO A;  5EEI A;  5THT A;  1P8O A;  5THS A;  3THH A;  3ZNS A;  4BZ9 A;  5HJ9 A;  3DJ8 A;  3MAX A;  3EZP A;  4QA2 A;  4Q42 A;  1C3P A;  1TBJ A;  4GSV A;  3Q9B A;  4MYN A;  3F06 A;  3GMZ A;  5DC5 A;  1WVA A;  5EEK A;  5G0G A;  3MFW A;  3E6V A;  3NIO A;  3KV2 A;  5G0X A;  5CEV A;  3NIP A;  5ICN B;  2AEB A;  1ZPG A;  3E6K A;  2VQQ A;  4ZUP A;  4ZUR A;  1T4S A;  4BZ7 A;  4RHK A;  4CQF A;  5DC6 A;  3EZT A;  4ZUN A;  1T4R A;  2A0M A;  4QA1 A;  3THE A;  3E9B A;  2PHO A;  5EFK B;  3EWF A;  5G0I A;  1PQ3 A;  1C3S A;  5IWG A;  5EEN A;  4CBY A;  1CEV A;  1T4T A;  1T5G A;  3SKK A;  1T4P A;  5RLA A;  4CEV A;  1HQF A;  5LI3 A;  4BZ6 A;  1T69 A;  4QA5 A;  2ZAV A;  5G0J A;  3MJL A;  4IU1 A;  4QA7 A;  3ZNR A;  1P8R A;  1ZZ1 A;  3F0R A;  3Q9E A;  4FCI A;  4HZE A;  2PHA A;  4QA0 A;  1RLA A;  4QA6 A;  1P8P A;  4RLA A;  4CBT A; 
#chains in the Genus database with same CATH homology
 4Q3R A;  4I06 A;  4GWC A;  1GQ6 A;  1TBH A;  4RHI A;  4IU0 A;  1GQ7 A;  4RHM A;  3M1R A;  3E8Z A;  4G3H A;  3NIQ A;  2RLA A;  2EF5 A;  1HQX A;  4RHL A;  4GSM A;  3MMR A;  1HQH A;  1P8N A;  4Q3S A;  3CEV A;  3F80 A;  4ITY A;  3LP4 A;  2PLL A;  1TBL A;  4Q40 A;  4RHQ A;  4Q3U A;  4IXV A;  4Q3R C;  1T5F A;  4Q3T A;  4RHJ A;  3RLA A;  1XFK A;  4Q41 A;  4MXR A;  4Q3V A;  3TH7 A;  3SL1 A;  1P8S A;  4HWW A;  4FCK A;  2CEV A;  3GN0 A;  3THJ A;  1R1O A;  4MYL A;  4Q3P A;  4IU5 A;  4MYF A;  4GSZ A;  4IE3 A;  3E8Q A;  3PZL A;  3SL0 A;  4IE1 A;  1P8M A;  3MFV A;  4IXU A;  1ZPE A;  1P8Q A;  1WOI A;  4HXQ A;  3TF3 A;  2EIV A;  5HJA A;  1WOH A;  1HQ5 A;  1TA1 A;  2EF4 A;  4MYK A;  1HQG A;  1D3V A;  4Q3Q A;  4IU4 A;  4GWD A;  1WOG A;  1WVB A;  3SJT A;  4DZ4 A;  4IE2 A;  3LHL A;  3LP7 A;  3THH A;  1P8O A;  5HJ9 A;  3DJ8 A;  4Q42 A;  1TBJ A;  4GSV A;  4MYN A;  3GMZ A;  1WVA A;  3MFW A;  3E6V A;  3NIO A;  3KV2 A;  5CEV A;  3NIP A;  2AEB A;  1ZPG A;  3E6K A;  1T4S A;  4RHK A;  1T4R A;  2A0M A;  3THE A;  3E9B A;  2PHO A;  1PQ3 A;  1CEV A;  1T4T A;  1T5G A;  3SKK A;  1T4P A;  5RLA A;  4CEV A;  1HQF A;  2ZAV A;  3MJL A;  4IU1 A;  1P8R A;  4FCI A;  4HZE A;  2PHA A;  1RLA A;  1P8P A;  4RLA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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