4Q42 | Genus

Total Genus 129

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	129
sequence length	345
structure length	336
Chain Sequence	KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQTA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Schistosoma mansoni
publication title	Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. pubmed doi rcsb
molecule keywords	Arginase
total genus	129
structure length	336
sequence length	345
chains with identical sequence	B, C, D
ec nomenclature	ec 3.5.3.1: Arginase.
pdb deposition date	2014-04-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00491	Arginase	Arginase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.800.10	Alpha Beta	3-Layer(aba) Sandwich	Arginase; Chain A	Ureohydrolase domain	4q42A00

4RHQA 4Q3QA 2EF5A 4Q3PA 3CEVA 3SL0A 3THJA 1ZPEA 4RLAA 3LHLA 3GMZA 4MYLA 3NIOA 3LP4A 2CEVA 4FCKA 2PHAA 4RHKA 4MYKA 4IE2A 1T5GA 4Q3TA 3E8ZA 1P8SA 4MXRA 1GQ6A 3KV2A 1HQHA 1T4TA 3LP7A 4GSMA 1XFKA 3RLAA 3DJ8A 2EF4A 1D3VA 1HQGA 1HQ5A 4GSZA 3MJLA 2A0MA 3PZLA 1ZPGA 2ZAVA 4HXQA 1TBHA 4RHLA 3TH7A 1P8PA 3SKKA 1GQ7A 3F80A 2EIVA 4Q3RC 3MFVA 4IE3A 3MMRA 4Q42A 1T4RA 1T5FA 4RHIA 4MYNA 1WOGA 1T4PA 1RLAA 3SL1A 4DZ4A 4Q3SA 3SJTA 1R1OA 4IXUA 4FCIA 3THEA 1WVBA 1TA1A 4MYFA 3TF3A 1P8QA 4Q3RA 3THHA 4GSVA 4HZEA 4RHMA 4IU5A 3M1RA 1P8MA 3NIQA 2PLLA 4CEVA 4GWCA 1HQXA 1WVAA 4HWWA 4Q3VA 4G3HA 3E9BA 1P8NA 4Q40A 1P8RA 3E6KA 5CEVA 1TBLA 2AEBA 4IU1A 4GWDA 4IU0A 1WOIA 4IU4A 1P8OA 3E6VA 3GN0A 3MFWA 4Q41A 2PHOA 4I06A 4IXVA 1PQ3A 1WOHA 1HQFA 5HJ9A 3NIPA 4Q3UA 2RLAA 3E8QA 4RHJA 1CEVA 1T4SA 1TBJA 5HJAA 4IE1A 5RLAA 4ITYA
chains in the Genus database with same CATH superfamily

4RHQA 4Q3QA 5EFKB 5G1AA 2EF5A 4Q3PA 3CEVA 3SL0A 3THJA 5G10A 4ZUMA 5ICNB 1ZPEA 4RLAA 4QA6A 3LHLA 3F06A 3GMZA 3MZ3A 4MYLA 3NIOA 5G12A 3LP4A 5THUA 2CEVA 4FCKA 5JI5A 2PHAA 1VKGA 4LXZA 4IE2A 4MYKA 4RHKA 5DC6A 1T5GA 4Q3TA 5EEKA 5EFJD 1ZZ3A 3ZNSA 3E8ZA 1P8SA 3MENA 4MXRA 5EEMA 4ZUPA 2GH6A 5D1BA 1C3PA 1GQ6A 3KV2A 5G11A 3SFFA 5THVA 1T64A 4BKXB 1HQHA 1T4TA 3LP7A 4GSMA 4QA2A 1XFKA 2VQVA 3RLAA 5A2SA 3DJ8A 2EF4A 1D3VA 2V5XA 1HQGA 5EFGA 1HQ5A 4ZUQA 4QA4A 5EF7A 1T69A 4GSZA 5FUEA 3MJLA 5THTA 2A0MA 3PZLA 4BZ8A 4BZ9A 1ZPGA 2ZAVA 4HXQA 1TBHA 4RHLA 3ZNRA 3TH7A 1P8PA 1ZZ0A 5G13A 3SKKA 5G1BA 1GQ7A 3C10A 3F80A 5G0IA 2EIVA 4CBYA 4Q3RC 5EFHA 3MFVA 4IE3A 3MMRA 3RQDA 4Q42A 4QA0A 4RN2A 3F07A 1T4RA 1T5FA 3Q9FA 2VQJA 4RHIA 4RN1A 3EZPA 4MYNA 1WOGA 2VQMA 5DC7A 4ZUNA 1T4PA 1RLAA 3SL1A 4DZ4A 4BZ5A 4Q3SA 5DC8A 3SJTA 1ZZ1A 1R1OA 3MAXA 4QA3A 5EFNA 4IXUA 4FCIA 3THEA 4QA5A 5EF8A 1WVBA 5FCWA 5G0GA 1TA1A 4MYFA 5G0XA 5IWGA 5BWZA 3TF3A 1P8QA 4Q3RA 5G0HA 3THHA 4GSVA 4HZEA 5LI3A 4RHMA 4ZURA 4QA1A 3C0YA 4IU5A 4QA7A 5G1CA 4CQFA 3M1RA 4BZ6A 1P8MA 3NIQA 5G17A 3MZ7A 2PLLA 5G0JA 4CEVA 3MZ4A 4GWCA 2VQOA 1HQXA 1WVAA 4BZ7A 4HWWA 3EWFA 4Q3VA 3F0RA 1C3SA 4G3HA 3E9BA 1P8NA 1W22A 4Q40A 4RN0A 1P8RA 3E6KA 5CEVA 1TBLA 2AEBA 3Q9CA 4IU1A 4GWDA 4IU0A 1WOIA 4IU4A 5G3WA 1P8OA 3SFHA 5D1DA 3E6VA 3GN0A 3MFWA 5EFBD 4LY1A 4CBTA 4Q41A 3EZTA 2PHOA 1T67A 4ZUOA 3MZ6A 5THSA 2VQWG 4I06A 4A69A 5EEFA 5EEIA 2VCGA 4IXVA 1PQ3A 2V5WA 5D1CA 3Q9BA 5DC5A 1WOHA 1HQFA 5HJ9A 3NIPA 4Q3UA 2VQQA 2RLAA 3E8QA 4RHJA 5EENA 5G0YA 1CEVA 1T4SA 1TBJA 3EW8A 5HJAA 4IE1A 1C3RA 3Q9EA 3C0ZA 5IX0A 5RLAA 4ITYA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4RHQ A;  4Q3Q A;  2EF5 A;  4Q3P A;  3CEV A;  3SL0 A;  3THJ A;  1ZPE A;  4RLA A;  3LHL A;  3GMZ A;  4MYL A;  3NIO A;  3LP4 A;  2CEV A;  4FCK A;  2PHA A;  4RHK A;  4MYK A;  4IE2 A;  1T5G A;  4Q3T A;  3E8Z A;  1P8S A;  4MXR A;  1GQ6 A;  3KV2 A;  1HQH A;  1T4T A;  3LP7 A;  4GSM A;  1XFK A;  3RLA A;  3DJ8 A;  2EF4 A;  1D3V A;  1HQG A;  1HQ5 A;  4GSZ A;  3MJL A;  2A0M A;  3PZL A;  1ZPG A;  2ZAV A;  4HXQ A;  1TBH A;  4RHL A;  3TH7 A;  1P8P A;  3SKK A;  1GQ7 A;  3F80 A;  2EIV A;  4Q3R C;  3MFV A;  4IE3 A;  3MMR A;  4Q42 A;  1T4R A;  1T5F A;  4RHI A;  4MYN A;  1WOG A;  1T4P A;  1RLA A;  3SL1 A;  4DZ4 A;  4Q3S A;  3SJT A;  1R1O A;  4IXU A;  4FCI A;  3THE A;  1WVB A;  1TA1 A;  4MYF A;  3TF3 A;  1P8Q A;  4Q3R A;  3THH A;  4GSV A;  4HZE A;  4RHM A;  4IU5 A;  3M1R A;  1P8M A;  3NIQ A;  2PLL A;  4CEV A;  4GWC A;  1HQX A;  1WVA A;  4HWW A;  4Q3V A;  4G3H A;  3E9B A;  1P8N A;  4Q40 A;  1P8R A;  3E6K A;  5CEV A;  1TBL A;  2AEB A;  4IU1 A;  4GWD A;  4IU0 A;  1WOI A;  4IU4 A;  1P8O A;  3E6V A;  3GN0 A;  3MFW A;  4Q41 A;  2PHO A;  4I06 A;  4IXV A;  1PQ3 A;  1WOH A;  1HQF A;  5HJ9 A;  3NIP A;  4Q3U A;  2RLA A;  3E8Q A;  4RHJ A;  1CEV A;  1T4S A;  1TBJ A;  5HJA A;  4IE1 A;  5RLA A;  4ITY A; 
#chains in the Genus database with same CATH topology
 4RHQ A;  4Q3Q A;  5EFK B;  5G1A A;  2EF5 A;  4Q3P A;  3CEV A;  3SL0 A;  3THJ A;  5G10 A;  4ZUM A;  5ICN B;  1ZPE A;  4RLA A;  4QA6 A;  3LHL A;  3F06 A;  3GMZ A;  3MZ3 A;  4MYL A;  3NIO A;  5G12 A;  3LP4 A;  5THU A;  2CEV A;  4FCK A;  5JI5 A;  2PHA A;  1VKG A;  4LXZ A;  4IE2 A;  4MYK A;  4RHK A;  5DC6 A;  1T5G A;  4Q3T A;  5EEK A;  5EFJ D;  1ZZ3 A;  3ZNS A;  3E8Z A;  1P8S A;  3MEN A;  4MXR A;  5EEM A;  4ZUP A;  2GH6 A;  5D1B A;  1C3P A;  1GQ6 A;  3KV2 A;  5G11 A;  3SFF A;  5THV A;  1T64 A;  4BKX B;  1HQH A;  1T4T A;  3LP7 A;  4GSM A;  4QA2 A;  1XFK A;  2VQV A;  3RLA A;  5A2S A;  3DJ8 A;  2EF4 A;  1D3V A;  2V5X A;  1HQG A;  5EFG A;  1HQ5 A;  4ZUQ A;  4QA4 A;  5EF7 A;  1T69 A;  4GSZ A;  5FUE A;  3MJL A;  5THT A;  2A0M A;  3PZL A;  4BZ8 A;  4BZ9 A;  1ZPG A;  2ZAV A;  4HXQ A;  1TBH A;  4RHL A;  3ZNR A;  3TH7 A;  1P8P A;  1ZZ0 A;  5G13 A;  3SKK A;  5G1B A;  1GQ7 A;  3C10 A;  3F80 A;  5G0I A;  2EIV A;  4CBY A;  4Q3R C;  5EFH A;  3MFV A;  4IE3 A;  3MMR A;  3RQD A;  4Q42 A;  4QA0 A;  4RN2 A;  3F07 A;  1T4R A;  1T5F A;  3Q9F A;  2VQJ A;  4RHI A;  4RN1 A;  3EZP A;  4MYN A;  1WOG A;  2VQM A;  5DC7 A;  4ZUN A;  1T4P A;  1RLA A;  3SL1 A;  4DZ4 A;  4BZ5 A;  4Q3S A;  5DC8 A;  3SJT A;  1ZZ1 A;  1R1O A;  3MAX A;  4QA3 A;  5EFN A;  4IXU A;  4FCI A;  3THE A;  4QA5 A;  5EF8 A;  1WVB A;  5FCW A;  5G0G A;  1TA1 A;  4MYF A;  5G0X A;  5IWG A;  5BWZ A;  3TF3 A;  1P8Q A;  4Q3R A;  5G0H A;  3THH A;  4GSV A;  4HZE A;  5LI3 A;  4RHM A;  4ZUR A;  4QA1 A;  3C0Y A;  4IU5 A;  4QA7 A;  5G1C A;  4CQF A;  3M1R A;  4BZ6 A;  1P8M A;  3NIQ A;  5G17 A;  3MZ7 A;  2PLL A;  5G0J A;  4CEV A;  3MZ4 A;  4GWC A;  2VQO A;  1HQX A;  1WVA A;  4BZ7 A;  4HWW A;  3EWF A;  4Q3V A;  3F0R A;  1C3S A;  4G3H A;  3E9B A;  1P8N A;  1W22 A;  4Q40 A;  4RN0 A;  1P8R A;  3E6K A;  5CEV A;  1TBL A;  2AEB A;  3Q9C A;  4IU1 A;  4GWD A;  4IU0 A;  1WOI A;  4IU4 A;  5G3W A;  1P8O A;  3SFH A;  5D1D A;  3E6V A;  3GN0 A;  3MFW A;  5EFB D;  4LY1 A;  4CBT A;  4Q41 A;  3EZT A;  2PHO A;  1T67 A;  4ZUO A;  3MZ6 A;  5THS A;  2VQW G;  4I06 A;  4A69 A;  5EEF A;  5EEI A;  2VCG A;  4IXV A;  1PQ3 A;  2V5W A;  5D1C A;  3Q9B A;  5DC5 A;  1WOH A;  1HQF A;  5HJ9 A;  3NIP A;  4Q3U A;  2VQQ A;  2RLA A;  3E8Q A;  4RHJ A;  5EEN A;  5G0Y A;  1CEV A;  1T4S A;  1TBJ A;  3EW8 A;  5HJA A;  4IE1 A;  1C3R A;  3Q9E A;  3C0Z A;  5IX0 A;  5RLA A;  4ITY A; 
#chains in the Genus database with same CATH homology
 4RHQ A;  4Q3Q A;  2EF5 A;  4Q3P A;  3CEV A;  3SL0 A;  3THJ A;  1ZPE A;  4RLA A;  3LHL A;  3GMZ A;  4MYL A;  3NIO A;  3LP4 A;  2CEV A;  4FCK A;  2PHA A;  4RHK A;  4MYK A;  4IE2 A;  1T5G A;  4Q3T A;  3E8Z A;  1P8S A;  4MXR A;  1GQ6 A;  3KV2 A;  1HQH A;  1T4T A;  3LP7 A;  4GSM A;  1XFK A;  3RLA A;  3DJ8 A;  2EF4 A;  1D3V A;  1HQG A;  1HQ5 A;  4GSZ A;  3MJL A;  2A0M A;  3PZL A;  1ZPG A;  2ZAV A;  4HXQ A;  1TBH A;  4RHL A;  3TH7 A;  1P8P A;  3SKK A;  1GQ7 A;  3F80 A;  2EIV A;  4Q3R C;  3MFV A;  4IE3 A;  3MMR A;  4Q42 A;  1T4R A;  1T5F A;  4RHI A;  4MYN A;  1WOG A;  1T4P A;  1RLA A;  3SL1 A;  4DZ4 A;  4Q3S A;  3SJT A;  1R1O A;  4IXU A;  4FCI A;  3THE A;  1WVB A;  1TA1 A;  4MYF A;  3TF3 A;  1P8Q A;  4Q3R A;  3THH A;  4GSV A;  4HZE A;  4RHM A;  4IU5 A;  3M1R A;  1P8M A;  3NIQ A;  2PLL A;  4CEV A;  4GWC A;  1HQX A;  1WVA A;  4HWW A;  4Q3V A;  4G3H A;  3E9B A;  1P8N A;  4Q40 A;  1P8R A;  3E6K A;  5CEV A;  1TBL A;  2AEB A;  4IU1 A;  4GWD A;  4IU0 A;  1WOI A;  4IU4 A;  1P8O A;  3E6V A;  3GN0 A;  3MFW A;  4Q41 A;  2PHO A;  4I06 A;  4IXV A;  1PQ3 A;  1WOH A;  1HQF A;  5HJ9 A;  3NIP A;  4Q3U A;  2RLA A;  3E8Q A;  4RHJ A;  1CEV A;  1T4S A;  1TBJ A;  5HJA A;  4IE1 A;  5RLA A;  4ITY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4Q42A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations