4CEVA

Arginase from bacillus caldevelox, l-ornithine complex
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
298
structure length
298
Chain Sequence
KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLMAAAAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus caldovelox
molecule keywords PROTEIN (ARGINASE)
total genus 112
structure length 298
sequence length 298
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 1999-03-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4cevA00
1P8RA 3MFVA 3TH7A 1P8PA 1TA1A 2EIVA 4MYKA 3PZLA 3DJ8A 4IU4A 3THHA 3THJA 5HJ9A 3E6VA 3KV2A 1TBLA 2CEVA 4DZ4A 1WOGA 4Q3SA 3LP7A 4HZEA 4IU1A 4Q3TA 1WOIA 1P8SA 3MMRA 3E8QA 3LP4A 3E6KA 4MXRA 1HQHA 2A0MA 4GWCA 4IXVA 1GQ6A 4MYFA 4Q40A 4Q3VA 2EF5A 5CEVA 4ITYA 1HQFA 1T4RA 1P8OA 1HQ5A 1HQXA 1P8MA 4FCIA 4G3HA 1T4SA 4Q3RA 1CEVA 4GSVA 3NIQA 1HQGA 4IXUA 3SL0A 4FCKA 4HWWA 4GSZA 4RHLA 2ZAVA 4RLAA 1GQ7A 2PLLA 1R1OA 2EF4A 3NIPA 4HXQA 5HJAA 4IE1A 1WOHA 4Q42A 4Q3PA 3GN0A 4GSMA 3SKKA 3TF3A 4RHMA 1P8NA 1RLAA 2RLAA 3MFWA 3GMZA 4CEVA 4RHJA 3LHLA 1XFKA 4RHQA 4MYNA 4Q41A 3CEVA 3E9BA 3RLAA 1PQ3A 1T5GA 3M1RA 1ZPEA 1T5FA 5RLAA 3NIOA 4MYLA 2PHAA 3MJLA 3SJTA 4GWDA 4IU5A 2AEBA 4Q3QA 1T4PA 1TBHA 4Q3UA 4RHIA 3THEA 4IU0A 1D3VA 4Q3RC 1ZPGA 1P8QA 4I06A 3SL1A 3E8ZA 4IE3A 1WVBA 1WVAA 2PHOA 1TBJA 4RHKA 1T4TA 4IE2A 3F80A
chains in the Genus database with same CATH superfamily
1P8RA 3MFVA 5THSA 3ZNRA 3TH7A 1P8PA 1TA1A 2VQWG 5THUA 3ZNSA 1W22A 2VQQA 5G12A 4MYKA 3PZLA 5IWGA 4BKXB 3DJ8A 4IU4A 3THHA 1T64A 3THJA 3MZ4A 5HJ9A 4A69A 3MZ7A 4CBYA 3E6VA 3KV2A 4QA5A 1TBLA 2CEVA 1T69A 4DZ4A 1WOGA 4Q3SA 4RN1A 3LP7A 4HZEA 1T67A 4IU1A 4Q3TA 5G0XA 1WOIA 3SFFA 1P8SA 2V5WA 5D1BA 5G0IA 2VCGA 2VQMA 3MMRA 5DC7A 3E8QA 2V5XA 1C3RA 3LP4A 5G0YA 3SFHA 3E6KA 5BWZA 4MXRA 5D1CA 1HQHA 2A0MA 4BZ7A 4GWCA 3Q9EA 5G3WA 4QA4A 4IXVA 4QA2A 1GQ6A 4MYFA 1ZZ3A 4Q40A 4QA3A 4Q3VA 4BZ5A 3F80A 2EF5A 3Q9BA 4LY1A 5CEVA 3C0YA 2VQOA 4ITYA 1HQFA 4ZUQA 1T4RA 1P8OA 1HQ5A 1HQXA 4BZ6A 1P8MA 4FCIA 4G3HA 5EFKB 3EZTA 1T4SA 4Q3RA 1CEVA 4GSVA 5EF7A 4ZURA 4BZ9A 4QA7A 3F06A 3NIQA 1HQGA 5G1AA 4IXUA 3SL0A 4FCKA 4HWWA 5ICNB 2VQVA 5DC8A 4GSZA 4RHLA 2ZAVA 4RLAA 1GQ7A 1C3SA 2PLLA 1R1OA 5EENA 5IX0A 2EF4A 3C10A 3F07A 5G1CA 3Q9CA 4BZ8A 3NIPA 4HXQA 5HJAA 3C0ZA 3MAXA 2GH6A 5G17A 4IE1A 2VQJA 1WOHA 3MENA 3MZ3A 4Q42A 4ZUNA 5G11A 1C3PA 4Q3PA 3GN0A 5EFHA 3EZPA 5EEFA 4GSMA 5EEKA 1ZZ1A 5G0JA 3SKKA 3TF3A 4RHMA 4RN0A 1P8NA 1RLAA 2RLAA 3MFWA 5D1DA 5G10A 5G0HA 3GMZA 4CEVA 4RHJA 4QA0A 3LHLA 1XFKA 4RHQA 4MYNA 5G0GA 5DC5A 4Q41A 3CEVA 5EEMA 5FUEA 5THTA 1ZZ0A 3EW8A 3E9BA 3MZ6A 3RLAA 5A2SA 1PQ3A 1T5GA 5EEIA 3M1RA 1VKGA 1ZPEA 1T5FA 3Q9FA 5RLAA 4LXZA 4RN2A 3NIOA 4ZUMA 4MYLA 2PHAA 3MJLA 3SJTA 4GWDA 4IU5A 2AEBA 4Q3QA 4QA1A 1T4PA 5EFNA 1TBHA 4Q3UA 4RHIA 3THEA 3RQDA 4IU0A 4ZUOA 1D3VA 5G13A 4Q3RC 1ZPGA 5EFJD 1P8QA 4I06A 5DC6A 5EF8A 3SL1A 3E8ZA 3F0RA 4CQFA 5LI3A 5THVA 4IE3A 1WVBA 1WVAA 5EFGA 5JI5A 2PHOA 1TBJA 5EFBD 4RHKA 1T4TA 4IE2A 5G1BA 4ZUPA 4CBTA 4QA6A 3EWFA 2EIVA 5FCWA
chains in the Genus database with same CATH topology
1P8RA 3MFVA 3TH7A 1P8PA 1TA1A 2EIVA 4MYKA 3PZLA 3DJ8A 4IU4A 3THHA 3THJA 5HJ9A 3E6VA 3KV2A 1TBLA 2CEVA 4DZ4A 1WOGA 4Q3SA 3LP7A 4HZEA 4IU1A 4Q3TA 1WOIA 1P8SA 3MMRA 3E8QA 3LP4A 3E6KA 4MXRA 1HQHA 2A0MA 4GWCA 4IXVA 1GQ6A 4MYFA 4Q40A 4Q3VA 2EF5A 5CEVA 4ITYA 1HQFA 1T4RA 1P8OA 1HQ5A 1HQXA 1P8MA 4FCIA 4G3HA 1T4SA 4Q3RA 1CEVA 4GSVA 3NIQA 1HQGA 4IXUA 3SL0A 4FCKA 4HWWA 4GSZA 4RHLA 2ZAVA 4RLAA 1GQ7A 2PLLA 1R1OA 2EF4A 3NIPA 4HXQA 5HJAA 4IE1A 1WOHA 4Q42A 4Q3PA 3GN0A 4GSMA 3SKKA 3TF3A 4RHMA 1P8NA 1RLAA 2RLAA 3MFWA 3GMZA 4CEVA 4RHJA 3LHLA 1XFKA 4RHQA 4MYNA 4Q41A 3CEVA 3E9BA 3RLAA 1PQ3A 1T5GA 3M1RA 1ZPEA 1T5FA 5RLAA 3NIOA 4MYLA 2PHAA 3MJLA 3SJTA 4GWDA 4IU5A 2AEBA 4Q3QA 1T4PA 1TBHA 4Q3UA 4RHIA 3THEA 4IU0A 1D3VA 4Q3RC 1ZPGA 1P8QA 4I06A 3SL1A 3E8ZA 4IE3A 1WVBA 1WVAA 2PHOA 1TBJA 4RHKA 1T4TA 4IE2A 3F80A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P8R A;  3MFV A;  3TH7 A;  1P8P A;  1TA1 A;  2EIV A;  4MYK A;  3PZL A;  3DJ8 A;  4IU4 A;  3THH A;  3THJ A;  5HJ9 A;  3E6V A;  3KV2 A;  1TBL A;  2CEV A;  4DZ4 A;  1WOG A;  4Q3S A;  3LP7 A;  4HZE A;  4IU1 A;  4Q3T A;  1WOI A;  1P8S A;  3MMR A;  3E8Q A;  3LP4 A;  3E6K A;  4MXR A;  1HQH A;  2A0M A;  4GWC A;  4IXV A;  1GQ6 A;  4MYF A;  4Q40 A;  4Q3V A;  2EF5 A;  5CEV A;  4ITY A;  1HQF A;  1T4R A;  1P8O A;  1HQ5 A;  1HQX A;  1P8M A;  4FCI A;  4G3H A;  1T4S A;  4Q3R A;  1CEV A;  4GSV A;  3NIQ A;  1HQG A;  4IXU A;  3SL0 A;  4FCK A;  4HWW A;  4GSZ A;  4RHL A;  2ZAV A;  4RLA A;  1GQ7 A;  2PLL A;  1R1O A;  2EF4 A;  3NIP A;  4HXQ A;  5HJA A;  4IE1 A;  1WOH A;  4Q42 A;  4Q3P A;  3GN0 A;  4GSM A;  3SKK A;  3TF3 A;  4RHM A;  1P8N A;  1RLA A;  2RLA A;  3MFW A;  3GMZ A;  4CEV A;  4RHJ A;  3LHL A;  1XFK A;  4RHQ A;  4MYN A;  4Q41 A;  3CEV A;  3E9B A;  3RLA A;  1PQ3 A;  1T5G A;  3M1R A;  1ZPE A;  1T5F A;  5RLA A;  3NIO A;  4MYL A;  2PHA A;  3MJL A;  3SJT A;  4GWD A;  4IU5 A;  2AEB A;  4Q3Q A;  1T4P A;  1TBH A;  4Q3U A;  4RHI A;  3THE A;  4IU0 A;  1D3V A;  4Q3R C;  1ZPG A;  1P8Q A;  4I06 A;  3SL1 A;  3E8Z A;  4IE3 A;  1WVB A;  1WVA A;  2PHO A;  1TBJ A;  4RHK A;  1T4T A;  4IE2 A;  3F80 A; 
#chains in the Genus database with same CATH topology
 1P8R A;  3MFV A;  5THS A;  3ZNR A;  3TH7 A;  1P8P A;  1TA1 A;  2VQW G;  5THU A;  3ZNS A;  1W22 A;  2VQQ A;  5G12 A;  4MYK A;  3PZL A;  5IWG A;  4BKX B;  3DJ8 A;  4IU4 A;  3THH A;  1T64 A;  3THJ A;  3MZ4 A;  5HJ9 A;  4A69 A;  3MZ7 A;  4CBY A;  3E6V A;  3KV2 A;  4QA5 A;  1TBL A;  2CEV A;  1T69 A;  4DZ4 A;  1WOG A;  4Q3S A;  4RN1 A;  3LP7 A;  4HZE A;  1T67 A;  4IU1 A;  4Q3T A;  5G0X A;  1WOI A;  3SFF A;  1P8S A;  2V5W A;  5D1B A;  5G0I A;  2VCG A;  2VQM A;  3MMR A;  5DC7 A;  3E8Q A;  2V5X A;  1C3R A;  3LP4 A;  5G0Y A;  3SFH A;  3E6K A;  5BWZ A;  4MXR A;  5D1C A;  1HQH A;  2A0M A;  4BZ7 A;  4GWC A;  3Q9E A;  5G3W A;  4QA4 A;  4IXV A;  4QA2 A;  1GQ6 A;  4MYF A;  1ZZ3 A;  4Q40 A;  4QA3 A;  4Q3V A;  4BZ5 A;  3F80 A;  2EF5 A;  3Q9B A;  4LY1 A;  5CEV A;  3C0Y A;  2VQO A;  4ITY A;  1HQF A;  4ZUQ A;  1T4R A;  1P8O A;  1HQ5 A;  1HQX A;  4BZ6 A;  1P8M A;  4FCI A;  4G3H A;  5EFK B;  3EZT A;  1T4S A;  4Q3R A;  1CEV A;  4GSV A;  5EF7 A;  4ZUR A;  4BZ9 A;  4QA7 A;  3F06 A;  3NIQ A;  1HQG A;  5G1A A;  4IXU A;  3SL0 A;  4FCK A;  4HWW A;  5ICN B;  2VQV A;  5DC8 A;  4GSZ A;  4RHL A;  2ZAV A;  4RLA A;  1GQ7 A;  1C3S A;  2PLL A;  1R1O A;  5EEN A;  5IX0 A;  2EF4 A;  3C10 A;  3F07 A;  5G1C A;  3Q9C A;  4BZ8 A;  3NIP A;  4HXQ A;  5HJA A;  3C0Z A;  3MAX A;  2GH6 A;  5G17 A;  4IE1 A;  2VQJ A;  1WOH A;  3MEN A;  3MZ3 A;  4Q42 A;  4ZUN A;  5G11 A;  1C3P A;  4Q3P A;  3GN0 A;  5EFH A;  3EZP A;  5EEF A;  4GSM A;  5EEK A;  1ZZ1 A;  5G0J A;  3SKK A;  3TF3 A;  4RHM A;  4RN0 A;  1P8N A;  1RLA A;  2RLA A;  3MFW A;  5D1D A;  5G10 A;  5G0H A;  3GMZ A;  4CEV A;  4RHJ A;  4QA0 A;  3LHL A;  1XFK A;  4RHQ A;  4MYN A;  5G0G A;  5DC5 A;  4Q41 A;  3CEV A;  5EEM A;  5FUE A;  5THT A;  1ZZ0 A;  3EW8 A;  3E9B A;  3MZ6 A;  3RLA A;  5A2S A;  1PQ3 A;  1T5G A;  5EEI A;  3M1R A;  1VKG A;  1ZPE A;  1T5F A;  3Q9F A;  5RLA A;  4LXZ A;  4RN2 A;  3NIO A;  4ZUM A;  4MYL A;  2PHA A;  3MJL A;  3SJT A;  4GWD A;  4IU5 A;  2AEB A;  4Q3Q A;  4QA1 A;  1T4P A;  5EFN A;  1TBH A;  4Q3U A;  4RHI A;  3THE A;  3RQD A;  4IU0 A;  4ZUO A;  1D3V A;  5G13 A;  4Q3R C;  1ZPG A;  5EFJ D;  1P8Q A;  4I06 A;  5DC6 A;  5EF8 A;  3SL1 A;  3E8Z A;  3F0R A;  4CQF A;  5LI3 A;  5THV A;  4IE3 A;  1WVB A;  1WVA A;  5EFG A;  5JI5 A;  2PHO A;  1TBJ A;  5EFB D;  4RHK A;  1T4T A;  4IE2 A;  5G1B A;  4ZUP A;  4CBT A;  4QA6 A;  3EWF A;  2EIV A;  5FCW A; 
#chains in the Genus database with same CATH homology
 1P8R A;  3MFV A;  3TH7 A;  1P8P A;  1TA1 A;  2EIV A;  4MYK A;  3PZL A;  3DJ8 A;  4IU4 A;  3THH A;  3THJ A;  5HJ9 A;  3E6V A;  3KV2 A;  1TBL A;  2CEV A;  4DZ4 A;  1WOG A;  4Q3S A;  3LP7 A;  4HZE A;  4IU1 A;  4Q3T A;  1WOI A;  1P8S A;  3MMR A;  3E8Q A;  3LP4 A;  3E6K A;  4MXR A;  1HQH A;  2A0M A;  4GWC A;  4IXV A;  1GQ6 A;  4MYF A;  4Q40 A;  4Q3V A;  2EF5 A;  5CEV A;  4ITY A;  1HQF A;  1T4R A;  1P8O A;  1HQ5 A;  1HQX A;  1P8M A;  4FCI A;  4G3H A;  1T4S A;  4Q3R A;  1CEV A;  4GSV A;  3NIQ A;  1HQG A;  4IXU A;  3SL0 A;  4FCK A;  4HWW A;  4GSZ A;  4RHL A;  2ZAV A;  4RLA A;  1GQ7 A;  2PLL A;  1R1O A;  2EF4 A;  3NIP A;  4HXQ A;  5HJA A;  4IE1 A;  1WOH A;  4Q42 A;  4Q3P A;  3GN0 A;  4GSM A;  3SKK A;  3TF3 A;  4RHM A;  1P8N A;  1RLA A;  2RLA A;  3MFW A;  3GMZ A;  4CEV A;  4RHJ A;  3LHL A;  1XFK A;  4RHQ A;  4MYN A;  4Q41 A;  3CEV A;  3E9B A;  3RLA A;  1PQ3 A;  1T5G A;  3M1R A;  1ZPE A;  1T5F A;  5RLA A;  3NIO A;  4MYL A;  2PHA A;  3MJL A;  3SJT A;  4GWD A;  4IU5 A;  2AEB A;  4Q3Q A;  1T4P A;  1TBH A;  4Q3U A;  4RHI A;  3THE A;  4IU0 A;  1D3V A;  4Q3R C;  1ZPG A;  1P8Q A;  4I06 A;  3SL1 A;  3E8Z A;  4IE3 A;  1WVB A;  1WVA A;  2PHO A;  1TBJ A;  4RHK A;  1T4T A;  4IE2 A;  3F80 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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