4GSMA

Crystal structure of ni2+2-human arginase i
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 112
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gsmA00
4HXQA 4MYNA 1P8QA 3E9BA 4MYFA 3SKKA 3THHA 1P8NA 1GQ7A 4RHLA 4I06A 4GWDA 1P8RA 4MYLA 1TBLA 4Q3RC 4RHQA 2EIVA 4IE1A 1GQ6A 4FCKA 1WVAA 4IE2A 3DJ8A 3RLAA 1HQ5A 4CEVA 4Q41A 1TBJA 4Q3SA 4Q3RA 3NIOA 1P8MA 4HWWA 3KV2A 4ITYA 1P8SA 3MFWA 3THJA 4GWCA 3NIPA 2PLLA 1T4RA 4DZ4A 1HQHA 3SJTA 1HQGA 3F80A 4RHMA 4IXUA 1T5GA 4G3HA 4MYKA 4MXRA 1TBHA 1T4SA 3E6KA 1HQFA 3SL1A 2PHAA 1T4PA 1T5FA 4IU4A 4RLAA 2CEVA 1ZPEA 1T4TA 4IE3A 1ZPGA 1WOGA 3LHLA 1P8OA 2ZAVA 4Q3VA 4IXVA 5HJ9A 2A0MA 3E6VA 4RHJA 1WOHA 3MFVA 4Q3PA 1P8PA 1R1OA 2PHOA 2EF4A 1XFKA 3TH7A 3PZLA 4FCIA 4Q42A 1WVBA 4Q3QA 3CEVA 1TA1A 4GSZA 4GSMA 3E8QA 1RLAA 4Q3UA 3LP4A 1WOIA 1HQXA 3M1RA 5HJAA 1CEVA 5CEVA 3TF3A 3NIQA 1PQ3A 3GMZA 3MMRA 2RLAA 4IU5A 4GSVA 2AEBA 3E8ZA 2EF5A 3THEA 4Q3TA 1D3VA 4HZEA 3MJLA 4RHIA 5RLAA 3GN0A 4IU1A 4RHKA 4IU0A 3SL0A 4Q40A 3LP7A
chains in the Genus database with same CATH superfamily
4HXQA 2VQMA 1P8QA 4MYNA 3E9BA 4MYFA 5DC6A 5G0YA 5EEFA 3SKKA 3THHA 1P8NA 5G3WA 1GQ7A 1T67A 4I06A 4RHLA 3Q9BA 4GWDA 1P8RA 2VQQA 3MZ7A 1T64A 5G0HA 4MYLA 5THSA 1TBLA 3Q9CA 4Q3RC 4RHQA 2EIVA 4IE1A 3C10A 5G1BA 1GQ6A 3Q9EA 4FCKA 4ZUPA 5BWZA 1ZZ1A 1WVAA 5EFNA 5EFHA 4IE2A 3DJ8A 5G0JA 3F0RA 3RLAA 4RN0A 5IX0A 5JI5A 1HQ5A 4CEVA 4BZ5A 5G12A 5DC5A 4Q41A 1TBJA 4Q3SA 4Q3RA 3NIOA 1P8MA 4HWWA 3KV2A 1ZZ3A 4ITYA 1P8SA 4ZUOA 5EEIA 4Q40A 3MFWA 4A69A 5DC8A 3THJA 4GWCA 3NIPA 2PLLA 5G17A 5EF8A 4BZ9A 4CQFA 1T4RA 4DZ4A 1HQHA 3SJTA 1HQGA 3F80A 5G0IA 1W22A 5G13A 4RHMA 5A2SA 4IXUA 5EENA 1T5GA 4G3HA 4MYKA 4MXRA 4QA4A 1TBHA 2VQOA 5G10A 1T4SA 3E6KA 1HQFA 3C0ZA 3SL1A 4QA5A 2PHAA 2GH6A 3EW8A 4RN1A 4QA2A 2VQJA 1T4PA 1T5FA 4IU4A 4ZURA 3ZNRA 4BZ8A 4RLAA 2CEVA 5EFKB 1ZPEA 3EZPA 1T4TA 5EFGA 5EEMA 4IE3A 5IWGA 5LI3A 3MZ6A 5G1CA 2VCGA 5EFJD 2V5WA 1ZZ0A 4CBYA 1ZPGA 1WOGA 3SFFA 3LHLA 1P8OA 2ZAVA 4Q3VA 4IXVA 2VQVA 5HJ9A 4QA0A 4BZ6A 5EEKA 4ZUNA 1T69A 2A0MA 4ZUMA 3E6VA 4RHJA 5THUA 3ZNSA 5G0GA 1WOHA 3MFVA 4Q3PA 1P8PA 4QA3A 1R1OA 2PHOA 2EF4A 1XFKA 3F07A 3TH7A 3PZLA 4FCIA 4Q42A 1WVBA 3MAXA 3RQDA 4Q3QA 1C3SA 3CEVA 5EFBD 5THTA 1TA1A 4GSZA 3Q9FA 4RN2A 5FUEA 3E8QA 4GSMA 1RLAA 5THVA 4Q3UA 3LP4A 3MZ3A 1WOIA 1HQXA 3M1RA 5DC7A 5HJAA 1CEVA 5G1AA 5CEVA 3TF3A 5D1CA 3NIQA 1PQ3A 1VKGA 3EWFA 3F06A 3GMZA 4QA1A 4CBTA 3MMRA 2RLAA 2VQWG 4IU5A 4GSVA 3C0YA 2AEBA 3E8ZA 2EF5A 5FCWA 3THEA 5EF7A 4BKXB 4Q3TA 1D3VA 4HZEA 3MJLA 4LY1A 4RHIA 3MZ4A 3GN0A 4IU1A 5RLAA 4LXZA 4BZ7A 4RHKA 4QA7A 3SFHA 5G0XA 1C3RA 5D1DA 1C3PA 5G11A 4IU0A 3SL0A 3MENA 4ZUQA 5ICNB 5D1BA 2V5XA 4QA6A 3LP7A 3EZTA
chains in the Genus database with same CATH topology
4HXQA 4MYNA 1P8QA 3E9BA 4MYFA 3SKKA 3THHA 1P8NA 1GQ7A 4RHLA 4I06A 4GWDA 1P8RA 4MYLA 1TBLA 4Q3RC 4RHQA 2EIVA 4IE1A 1GQ6A 4FCKA 1WVAA 4IE2A 3DJ8A 3RLAA 1HQ5A 4CEVA 4Q41A 1TBJA 4Q3SA 4Q3RA 3NIOA 1P8MA 4HWWA 3KV2A 4ITYA 1P8SA 3MFWA 3THJA 4GWCA 3NIPA 2PLLA 1T4RA 4DZ4A 1HQHA 3SJTA 1HQGA 3F80A 4RHMA 4IXUA 1T5GA 4G3HA 4MYKA 4MXRA 1TBHA 1T4SA 3E6KA 1HQFA 3SL1A 2PHAA 1T4PA 1T5FA 4IU4A 4RLAA 2CEVA 1ZPEA 1T4TA 4IE3A 1ZPGA 1WOGA 3LHLA 1P8OA 2ZAVA 4Q3VA 4IXVA 5HJ9A 2A0MA 3E6VA 4RHJA 1WOHA 3MFVA 4Q3PA 1P8PA 1R1OA 2PHOA 2EF4A 1XFKA 3TH7A 3PZLA 4FCIA 4Q42A 1WVBA 4Q3QA 3CEVA 1TA1A 4GSZA 4GSMA 3E8QA 1RLAA 4Q3UA 3LP4A 1WOIA 1HQXA 3M1RA 5HJAA 1CEVA 5CEVA 3TF3A 3NIQA 1PQ3A 3GMZA 3MMRA 2RLAA 4IU5A 4GSVA 2AEBA 3E8ZA 2EF5A 3THEA 4Q3TA 1D3VA 4HZEA 3MJLA 4RHIA 5RLAA 3GN0A 4IU1A 4RHKA 4IU0A 3SL0A 4Q40A 3LP7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HXQ A;  4MYN A;  1P8Q A;  3E9B A;  4MYF A;  3SKK A;  3THH A;  1P8N A;  1GQ7 A;  4RHL A;  4I06 A;  4GWD A;  1P8R A;  4MYL A;  1TBL A;  4Q3R C;  4RHQ A;  2EIV A;  4IE1 A;  1GQ6 A;  4FCK A;  1WVA A;  4IE2 A;  3DJ8 A;  3RLA A;  1HQ5 A;  4CEV A;  4Q41 A;  1TBJ A;  4Q3S A;  4Q3R A;  3NIO A;  1P8M A;  4HWW A;  3KV2 A;  4ITY A;  1P8S A;  3MFW A;  3THJ A;  4GWC A;  3NIP A;  2PLL A;  1T4R A;  4DZ4 A;  1HQH A;  3SJT A;  1HQG A;  3F80 A;  4RHM A;  4IXU A;  1T5G A;  4G3H A;  4MYK A;  4MXR A;  1TBH A;  1T4S A;  3E6K A;  1HQF A;  3SL1 A;  2PHA A;  1T4P A;  1T5F A;  4IU4 A;  4RLA A;  2CEV A;  1ZPE A;  1T4T A;  4IE3 A;  1ZPG A;  1WOG A;  3LHL A;  1P8O A;  2ZAV A;  4Q3V A;  4IXV A;  5HJ9 A;  2A0M A;  3E6V A;  4RHJ A;  1WOH A;  3MFV A;  4Q3P A;  1P8P A;  1R1O A;  2PHO A;  2EF4 A;  1XFK A;  3TH7 A;  3PZL A;  4FCI A;  4Q42 A;  1WVB A;  4Q3Q A;  3CEV A;  1TA1 A;  4GSZ A;  4GSM A;  3E8Q A;  1RLA A;  4Q3U A;  3LP4 A;  1WOI A;  1HQX A;  3M1R A;  5HJA A;  1CEV A;  5CEV A;  3TF3 A;  3NIQ A;  1PQ3 A;  3GMZ A;  3MMR A;  2RLA A;  4IU5 A;  4GSV A;  2AEB A;  3E8Z A;  2EF5 A;  3THE A;  4Q3T A;  1D3V A;  4HZE A;  3MJL A;  4RHI A;  5RLA A;  3GN0 A;  4IU1 A;  4RHK A;  4IU0 A;  3SL0 A;  4Q40 A;  3LP7 A; 
#chains in the Genus database with same CATH topology
 4HXQ A;  2VQM A;  1P8Q A;  4MYN A;  3E9B A;  4MYF A;  5DC6 A;  5G0Y A;  5EEF A;  3SKK A;  3THH A;  1P8N A;  5G3W A;  1GQ7 A;  1T67 A;  4I06 A;  4RHL A;  3Q9B A;  4GWD A;  1P8R A;  2VQQ A;  3MZ7 A;  1T64 A;  5G0H A;  4MYL A;  5THS A;  1TBL A;  3Q9C A;  4Q3R C;  4RHQ A;  2EIV A;  4IE1 A;  3C10 A;  5G1B A;  1GQ6 A;  3Q9E A;  4FCK A;  4ZUP A;  5BWZ A;  1ZZ1 A;  1WVA A;  5EFN A;  5EFH A;  4IE2 A;  3DJ8 A;  5G0J A;  3F0R A;  3RLA A;  4RN0 A;  5IX0 A;  5JI5 A;  1HQ5 A;  4CEV A;  4BZ5 A;  5G12 A;  5DC5 A;  4Q41 A;  1TBJ A;  4Q3S A;  4Q3R A;  3NIO A;  1P8M A;  4HWW A;  3KV2 A;  1ZZ3 A;  4ITY A;  1P8S A;  4ZUO A;  5EEI A;  4Q40 A;  3MFW A;  4A69 A;  5DC8 A;  3THJ A;  4GWC A;  3NIP A;  2PLL A;  5G17 A;  5EF8 A;  4BZ9 A;  4CQF A;  1T4R A;  4DZ4 A;  1HQH A;  3SJT A;  1HQG A;  3F80 A;  5G0I A;  1W22 A;  5G13 A;  4RHM A;  5A2S A;  4IXU A;  5EEN A;  1T5G A;  4G3H A;  4MYK A;  4MXR A;  4QA4 A;  1TBH A;  2VQO A;  5G10 A;  1T4S A;  3E6K A;  1HQF A;  3C0Z A;  3SL1 A;  4QA5 A;  2PHA A;  2GH6 A;  3EW8 A;  4RN1 A;  4QA2 A;  2VQJ A;  1T4P A;  1T5F A;  4IU4 A;  4ZUR A;  3ZNR A;  4BZ8 A;  4RLA A;  2CEV A;  5EFK B;  1ZPE A;  3EZP A;  1T4T A;  5EFG A;  5EEM A;  4IE3 A;  5IWG A;  5LI3 A;  3MZ6 A;  5G1C A;  2VCG A;  5EFJ D;  2V5W A;  1ZZ0 A;  4CBY A;  1ZPG A;  1WOG A;  3SFF A;  3LHL A;  1P8O A;  2ZAV A;  4Q3V A;  4IXV A;  2VQV A;  5HJ9 A;  4QA0 A;  4BZ6 A;  5EEK A;  4ZUN A;  1T69 A;  2A0M A;  4ZUM A;  3E6V A;  4RHJ A;  5THU A;  3ZNS A;  5G0G A;  1WOH A;  3MFV A;  4Q3P A;  1P8P A;  4QA3 A;  1R1O A;  2PHO A;  2EF4 A;  1XFK A;  3F07 A;  3TH7 A;  3PZL A;  4FCI A;  4Q42 A;  1WVB A;  3MAX A;  3RQD A;  4Q3Q A;  1C3S A;  3CEV A;  5EFB D;  5THT A;  1TA1 A;  4GSZ A;  3Q9F A;  4RN2 A;  5FUE A;  3E8Q A;  4GSM A;  1RLA A;  5THV A;  4Q3U A;  3LP4 A;  3MZ3 A;  1WOI A;  1HQX A;  3M1R A;  5DC7 A;  5HJA A;  1CEV A;  5G1A A;  5CEV A;  3TF3 A;  5D1C A;  3NIQ A;  1PQ3 A;  1VKG A;  3EWF A;  3F06 A;  3GMZ A;  4QA1 A;  4CBT A;  3MMR A;  2RLA A;  2VQW G;  4IU5 A;  4GSV A;  3C0Y A;  2AEB A;  3E8Z A;  2EF5 A;  5FCW A;  3THE A;  5EF7 A;  4BKX B;  4Q3T A;  1D3V A;  4HZE A;  3MJL A;  4LY1 A;  4RHI A;  3MZ4 A;  3GN0 A;  4IU1 A;  5RLA A;  4LXZ A;  4BZ7 A;  4RHK A;  4QA7 A;  3SFH A;  5G0X A;  1C3R A;  5D1D A;  1C3P A;  5G11 A;  4IU0 A;  3SL0 A;  3MEN A;  4ZUQ A;  5ICN B;  5D1B A;  2V5X A;  4QA6 A;  3LP7 A;  3EZT A; 
#chains in the Genus database with same CATH homology
 4HXQ A;  4MYN A;  1P8Q A;  3E9B A;  4MYF A;  3SKK A;  3THH A;  1P8N A;  1GQ7 A;  4RHL A;  4I06 A;  4GWD A;  1P8R A;  4MYL A;  1TBL A;  4Q3R C;  4RHQ A;  2EIV A;  4IE1 A;  1GQ6 A;  4FCK A;  1WVA A;  4IE2 A;  3DJ8 A;  3RLA A;  1HQ5 A;  4CEV A;  4Q41 A;  1TBJ A;  4Q3S A;  4Q3R A;  3NIO A;  1P8M A;  4HWW A;  3KV2 A;  4ITY A;  1P8S A;  3MFW A;  3THJ A;  4GWC A;  3NIP A;  2PLL A;  1T4R A;  4DZ4 A;  1HQH A;  3SJT A;  1HQG A;  3F80 A;  4RHM A;  4IXU A;  1T5G A;  4G3H A;  4MYK A;  4MXR A;  1TBH A;  1T4S A;  3E6K A;  1HQF A;  3SL1 A;  2PHA A;  1T4P A;  1T5F A;  4IU4 A;  4RLA A;  2CEV A;  1ZPE A;  1T4T A;  4IE3 A;  1ZPG A;  1WOG A;  3LHL A;  1P8O A;  2ZAV A;  4Q3V A;  4IXV A;  5HJ9 A;  2A0M A;  3E6V A;  4RHJ A;  1WOH A;  3MFV A;  4Q3P A;  1P8P A;  1R1O A;  2PHO A;  2EF4 A;  1XFK A;  3TH7 A;  3PZL A;  4FCI A;  4Q42 A;  1WVB A;  4Q3Q A;  3CEV A;  1TA1 A;  4GSZ A;  4GSM A;  3E8Q A;  1RLA A;  4Q3U A;  3LP4 A;  1WOI A;  1HQX A;  3M1R A;  5HJA A;  1CEV A;  5CEV A;  3TF3 A;  3NIQ A;  1PQ3 A;  3GMZ A;  3MMR A;  2RLA A;  4IU5 A;  4GSV A;  2AEB A;  3E8Z A;  2EF5 A;  3THE A;  4Q3T A;  1D3V A;  4HZE A;  3MJL A;  4RHI A;  5RLA A;  3GN0 A;  4IU1 A;  4RHK A;  4IU0 A;  3SL0 A;  4Q40 A;  3LP7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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