4GSZA

Crystal structure of the zn2+5-human arginase i-abh complex
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Arginase-1
total genus 109
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gszA00
2PLLA 4Q3QA 4Q3RC 1ZPGA 3LP7A 1WVBA 1P8PA 4HWWA 1T5GA 4HXQA 1HQ5A 3KV2A 4FCIA 4GSZA 3TF3A 1HQFA 1ZPEA 4IE2A 4Q42A 2PHOA 4Q40A 4GSVA 4MYLA 3THEA 4RHJA 1P8QA 4IE1A 1WVAA 1RLAA 1T4TA 3GN0A 4Q3RA 1WOHA 2A0MA 4IU0A 4Q41A 3SL1A 1HQXA 4RHKA 1R1OA 1P8NA 1T4PA 1WOGA 4CEVA 3F80A 2CEVA 2EIVA 1WOIA 5HJAA 1CEVA 5RLAA 4I06A 4GWCA 2EF5A 3E9BA 5CEVA 4IU1A 4MYFA 4RHIA 3LHLA 2EF4A 2AEBA 3DJ8A 1XFKA 4MYNA 4ITYA 4Q3UA 1HQGA 4HZEA 1D3VA 3CEVA 1P8RA 1GQ7A 1P8OA 4RLAA 4RHQA 1P8SA 1TA1A 4IU5A 1T5FA 4GWDA 3THJA 3E6VA 1GQ6A 2PHAA 3GMZA 4IXUA 4Q3TA 3SKKA 4GSMA 3NIOA 1HQHA 3MFVA 4IXVA 4Q3VA 3LP4A 4MYKA 2RLAA 3MJLA 1TBLA 4G3HA 4RHMA 3MMRA 4IE3A 5HJ9A 4RHLA 3E6KA 4Q3PA 3NIPA 1T4RA 1TBHA 3THHA 3PZLA 3M1RA 1T4SA 4IU4A 1PQ3A 4DZ4A 4MXRA 3MFWA 3NIQA 4Q3SA 1TBJA 3SL0A 3SJTA 2ZAVA 3E8QA 4FCKA 1P8MA 3RLAA 3TH7A 3E8ZA
chains in the Genus database with same CATH superfamily
2PLLA 4Q3QA 4Q3RC 5ICNB 1ZPGA 2VQWG 3LP7A 4QA4A 1WVBA 1P8PA 4HWWA 5EFJD 5IX0A 5DC6A 1T5GA 4HXQA 1HQ5A 1C3PA 3KV2A 4FCIA 3Q9BA 4GSZA 3TF3A 1HQFA 3MZ6A 1ZPEA 4IE2A 4Q42A 2PHOA 2VQVA 3MAXA 4GSVA 4MYLA 1ZZ3A 4Q40A 5G3WA 4RHJA 1P8QA 4ZUOA 5EFHA 4ZUNA 5G1CA 4IE1A 3C0YA 4RN2A 1WVAA 3EZTA 5FUEA 4QA1A 4QA2A 1RLAA 1T4TA 1C3SA 5A2SA 3GN0A 3RQDA 4Q3RA 1WOHA 2A0MA 5G17A 4IU0A 4Q41A 3SL1A 4ZUQA 1HQXA 1T69A 3EWFA 5G1AA 4RHKA 1R1OA 4RN0A 1P8NA 1T4PA 5EEKA 1WOGA 4BZ6A 4CBYA 5THSA 4CEVA 2V5XA 5G0GA 3F07A 5FCWA 5EFNA 2V5WA 5EEFA 3F80A 2CEVA 2EIVA 1WOIA 5HJAA 1CEVA 5G11A 5RLAA 4BZ8A 5BWZA 4QA0A 4I06A 4GWCA 3THEA 2VCGA 2EF5A 3E9BA 5EEMA 4BKXB 4A69A 3SFFA 4IU1A 4BZ5A 5CEVA 4QA5A 3ZNRA 4MYFA 4RHIA 5D1DA 3LHLA 4BZ7A 2EF4A 4LXZA 2AEBA 3DJ8A 1T67A 5G0XA 5THTA 1XFKA 4MYNA 2VQQA 4ITYA 3F0RA 4Q3UA 1HQGA 4HZEA 1D3VA 3CEVA 5DC5A 1P8RA 1GQ7A 1P8OA 2VQMA 3C0ZA 5EFGA 5G0IA 2VQOA 4RLAA 4QA7A 4RHQA 1P8SA 1TA1A 5JI5A 3SFHA 1VKGA 5G0JA 4IU5A 4BZ9A 5THUA 1T5FA 1ZZ1A 4GWDA 3THJA 5EF7A 1ZZ0A 3E6VA 3MZ7A 1GQ6A 2PHAA 3GMZA 4IXUA 4Q3TA 5EFBD 4ZUMA 4GSMA 3SKKA 5THVA 3NIOA 1HQHA 4ZURA 3MFVA 4IXVA 4CBTA 2GH6A 3EZPA 4Q3VA 5G0YA 2VQJA 3LP4A 4MYKA 2RLAA 3EW8A 4LY1A 3MJLA 1TBLA 4G3HA 4RHMA 5EEIA 5G10A 3Q9FA 3MMRA 4IE3A 4ZUPA 5DC8A 5HJ9A 4RHLA 3E6KA 4RN1A 5EFKB 5EF8A 3ZNSA 4Q3PA 5IWGA 3NIPA 1T4RA 1TBHA 3THHA 3F06A 4CQFA 3PZLA 5G1BA 3M1RA 5D1BA 5D1CA 1T4SA 5G13A 4IU4A 1PQ3A 3Q9EA 4DZ4A 3C10A 4QA6A 4MXRA 3MFWA 3MENA 3NIQA 4Q3SA 5DC7A 1C3RA 1TBJA 5G0HA 5G12A 3MZ3A 3SL0A 3SJTA 3Q9CA 1W22A 3MZ4A 2ZAVA 5LI3A 3E8QA 4FCKA 1T64A 1P8MA 4QA3A 5EENA 3RLAA 3TH7A 3E8ZA
chains in the Genus database with same CATH topology
2PLLA 4Q3QA 4Q3RC 1ZPGA 3LP7A 1WVBA 1P8PA 4HWWA 1T5GA 4HXQA 1HQ5A 3KV2A 4FCIA 4GSZA 3TF3A 1HQFA 1ZPEA 4IE2A 4Q42A 2PHOA 4Q40A 4GSVA 4MYLA 3THEA 4RHJA 1P8QA 4IE1A 1WVAA 1RLAA 1T4TA 3GN0A 4Q3RA 1WOHA 2A0MA 4IU0A 4Q41A 3SL1A 1HQXA 4RHKA 1R1OA 1P8NA 1T4PA 1WOGA 4CEVA 3F80A 2CEVA 2EIVA 1WOIA 5HJAA 1CEVA 5RLAA 4I06A 4GWCA 2EF5A 3E9BA 5CEVA 4IU1A 4MYFA 4RHIA 3LHLA 2EF4A 2AEBA 3DJ8A 1XFKA 4MYNA 4ITYA 4Q3UA 1HQGA 4HZEA 1D3VA 3CEVA 1P8RA 1GQ7A 1P8OA 4RLAA 4RHQA 1P8SA 1TA1A 4IU5A 1T5FA 4GWDA 3THJA 3E6VA 1GQ6A 2PHAA 3GMZA 4IXUA 4Q3TA 3SKKA 4GSMA 3NIOA 1HQHA 3MFVA 4IXVA 4Q3VA 3LP4A 4MYKA 2RLAA 3MJLA 1TBLA 4G3HA 4RHMA 3MMRA 4IE3A 5HJ9A 4RHLA 3E6KA 4Q3PA 3NIPA 1T4RA 1TBHA 3THHA 3PZLA 3M1RA 1T4SA 4IU4A 1PQ3A 4DZ4A 4MXRA 3MFWA 3NIQA 4Q3SA 1TBJA 3SL0A 3SJTA 2ZAVA 3E8QA 4FCKA 1P8MA 3RLAA 3TH7A 3E8ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PLL A;  4Q3Q A;  4Q3R C;  1ZPG A;  3LP7 A;  1WVB A;  1P8P A;  4HWW A;  1T5G A;  4HXQ A;  1HQ5 A;  3KV2 A;  4FCI A;  4GSZ A;  3TF3 A;  1HQF A;  1ZPE A;  4IE2 A;  4Q42 A;  2PHO A;  4Q40 A;  4GSV A;  4MYL A;  3THE A;  4RHJ A;  1P8Q A;  4IE1 A;  1WVA A;  1RLA A;  1T4T A;  3GN0 A;  4Q3R A;  1WOH A;  2A0M A;  4IU0 A;  4Q41 A;  3SL1 A;  1HQX A;  4RHK A;  1R1O A;  1P8N A;  1T4P A;  1WOG A;  4CEV A;  3F80 A;  2CEV A;  2EIV A;  1WOI A;  5HJA A;  1CEV A;  5RLA A;  4I06 A;  4GWC A;  2EF5 A;  3E9B A;  5CEV A;  4IU1 A;  4MYF A;  4RHI A;  3LHL A;  2EF4 A;  2AEB A;  3DJ8 A;  1XFK A;  4MYN A;  4ITY A;  4Q3U A;  1HQG A;  4HZE A;  1D3V A;  3CEV A;  1P8R A;  1GQ7 A;  1P8O A;  4RLA A;  4RHQ A;  1P8S A;  1TA1 A;  4IU5 A;  1T5F A;  4GWD A;  3THJ A;  3E6V A;  1GQ6 A;  2PHA A;  3GMZ A;  4IXU A;  4Q3T A;  3SKK A;  4GSM A;  3NIO A;  1HQH A;  3MFV A;  4IXV A;  4Q3V A;  3LP4 A;  4MYK A;  2RLA A;  3MJL A;  1TBL A;  4G3H A;  4RHM A;  3MMR A;  4IE3 A;  5HJ9 A;  4RHL A;  3E6K A;  4Q3P A;  3NIP A;  1T4R A;  1TBH A;  3THH A;  3PZL A;  3M1R A;  1T4S A;  4IU4 A;  1PQ3 A;  4DZ4 A;  4MXR A;  3MFW A;  3NIQ A;  4Q3S A;  1TBJ A;  3SL0 A;  3SJT A;  2ZAV A;  3E8Q A;  4FCK A;  1P8M A;  3RLA A;  3TH7 A;  3E8Z A; 
#chains in the Genus database with same CATH topology
 2PLL A;  4Q3Q A;  4Q3R C;  5ICN B;  1ZPG A;  2VQW G;  3LP7 A;  4QA4 A;  1WVB A;  1P8P A;  4HWW A;  5EFJ D;  5IX0 A;  5DC6 A;  1T5G A;  4HXQ A;  1HQ5 A;  1C3P A;  3KV2 A;  4FCI A;  3Q9B A;  4GSZ A;  3TF3 A;  1HQF A;  3MZ6 A;  1ZPE A;  4IE2 A;  4Q42 A;  2PHO A;  2VQV A;  3MAX A;  4GSV A;  4MYL A;  1ZZ3 A;  4Q40 A;  5G3W A;  4RHJ A;  1P8Q A;  4ZUO A;  5EFH A;  4ZUN A;  5G1C A;  4IE1 A;  3C0Y A;  4RN2 A;  1WVA A;  3EZT A;  5FUE A;  4QA1 A;  4QA2 A;  1RLA A;  1T4T A;  1C3S A;  5A2S A;  3GN0 A;  3RQD A;  4Q3R A;  1WOH A;  2A0M A;  5G17 A;  4IU0 A;  4Q41 A;  3SL1 A;  4ZUQ A;  1HQX A;  1T69 A;  3EWF A;  5G1A A;  4RHK A;  1R1O A;  4RN0 A;  1P8N A;  1T4P A;  5EEK A;  1WOG A;  4BZ6 A;  4CBY A;  5THS A;  4CEV A;  2V5X A;  5G0G A;  3F07 A;  5FCW A;  5EFN A;  2V5W A;  5EEF A;  3F80 A;  2CEV A;  2EIV A;  1WOI A;  5HJA A;  1CEV A;  5G11 A;  5RLA A;  4BZ8 A;  5BWZ A;  4QA0 A;  4I06 A;  4GWC A;  3THE A;  2VCG A;  2EF5 A;  3E9B A;  5EEM A;  4BKX B;  4A69 A;  3SFF A;  4IU1 A;  4BZ5 A;  5CEV A;  4QA5 A;  3ZNR A;  4MYF A;  4RHI A;  5D1D A;  3LHL A;  4BZ7 A;  2EF4 A;  4LXZ A;  2AEB A;  3DJ8 A;  1T67 A;  5G0X A;  5THT A;  1XFK A;  4MYN A;  2VQQ A;  4ITY A;  3F0R A;  4Q3U A;  1HQG A;  4HZE A;  1D3V A;  3CEV A;  5DC5 A;  1P8R A;  1GQ7 A;  1P8O A;  2VQM A;  3C0Z A;  5EFG A;  5G0I A;  2VQO A;  4RLA A;  4QA7 A;  4RHQ A;  1P8S A;  1TA1 A;  5JI5 A;  3SFH A;  1VKG A;  5G0J A;  4IU5 A;  4BZ9 A;  5THU A;  1T5F A;  1ZZ1 A;  4GWD A;  3THJ A;  5EF7 A;  1ZZ0 A;  3E6V A;  3MZ7 A;  1GQ6 A;  2PHA A;  3GMZ A;  4IXU A;  4Q3T A;  5EFB D;  4ZUM A;  4GSM A;  3SKK A;  5THV A;  3NIO A;  1HQH A;  4ZUR A;  3MFV A;  4IXV A;  4CBT A;  2GH6 A;  3EZP A;  4Q3V A;  5G0Y A;  2VQJ A;  3LP4 A;  4MYK A;  2RLA A;  3EW8 A;  4LY1 A;  3MJL A;  1TBL A;  4G3H A;  4RHM A;  5EEI A;  5G10 A;  3Q9F A;  3MMR A;  4IE3 A;  4ZUP A;  5DC8 A;  5HJ9 A;  4RHL A;  3E6K A;  4RN1 A;  5EFK B;  5EF8 A;  3ZNS A;  4Q3P A;  5IWG A;  3NIP A;  1T4R A;  1TBH A;  3THH A;  3F06 A;  4CQF A;  3PZL A;  5G1B A;  3M1R A;  5D1B A;  5D1C A;  1T4S A;  5G13 A;  4IU4 A;  1PQ3 A;  3Q9E A;  4DZ4 A;  3C10 A;  4QA6 A;  4MXR A;  3MFW A;  3MEN A;  3NIQ A;  4Q3S A;  5DC7 A;  1C3R A;  1TBJ A;  5G0H A;  5G12 A;  3MZ3 A;  3SL0 A;  3SJT A;  3Q9C A;  1W22 A;  3MZ4 A;  2ZAV A;  5LI3 A;  3E8Q A;  4FCK A;  1T64 A;  1P8M A;  4QA3 A;  5EEN A;  3RLA A;  3TH7 A;  3E8Z A; 
#chains in the Genus database with same CATH homology
 2PLL A;  4Q3Q A;  4Q3R C;  1ZPG A;  3LP7 A;  1WVB A;  1P8P A;  4HWW A;  1T5G A;  4HXQ A;  1HQ5 A;  3KV2 A;  4FCI A;  4GSZ A;  3TF3 A;  1HQF A;  1ZPE A;  4IE2 A;  4Q42 A;  2PHO A;  4Q40 A;  4GSV A;  4MYL A;  3THE A;  4RHJ A;  1P8Q A;  4IE1 A;  1WVA A;  1RLA A;  1T4T A;  3GN0 A;  4Q3R A;  1WOH A;  2A0M A;  4IU0 A;  4Q41 A;  3SL1 A;  1HQX A;  4RHK A;  1R1O A;  1P8N A;  1T4P A;  1WOG A;  4CEV A;  3F80 A;  2CEV A;  2EIV A;  1WOI A;  5HJA A;  1CEV A;  5RLA A;  4I06 A;  4GWC A;  2EF5 A;  3E9B A;  5CEV A;  4IU1 A;  4MYF A;  4RHI A;  3LHL A;  2EF4 A;  2AEB A;  3DJ8 A;  1XFK A;  4MYN A;  4ITY A;  4Q3U A;  1HQG A;  4HZE A;  1D3V A;  3CEV A;  1P8R A;  1GQ7 A;  1P8O A;  4RLA A;  4RHQ A;  1P8S A;  1TA1 A;  4IU5 A;  1T5F A;  4GWD A;  3THJ A;  3E6V A;  1GQ6 A;  2PHA A;  3GMZ A;  4IXU A;  4Q3T A;  3SKK A;  4GSM A;  3NIO A;  1HQH A;  3MFV A;  4IXV A;  4Q3V A;  3LP4 A;  4MYK A;  2RLA A;  3MJL A;  1TBL A;  4G3H A;  4RHM A;  3MMR A;  4IE3 A;  5HJ9 A;  4RHL A;  3E6K A;  4Q3P A;  3NIP A;  1T4R A;  1TBH A;  3THH A;  3PZL A;  3M1R A;  1T4S A;  4IU4 A;  1PQ3 A;  4DZ4 A;  4MXR A;  3MFW A;  3NIQ A;  4Q3S A;  1TBJ A;  3SL0 A;  3SJT A;  2ZAV A;  3E8Q A;  4FCK A;  1P8M A;  3RLA A;  3TH7 A;  3E8Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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