4GWCA

Crystal structure of mn2+2,zn2+-human arginase i
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
313
structure length
313
Chain Sequence
SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and function of non-native metal clusters in human arginase I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Arginase-1
total genus 104
structure length 313
sequence length 313
chains with identical sequence B
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2012-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4gwcA00
3LP4A 2EIVA 4IE2A 1TBLA 4Q42A 1GQ7A 4G3HA 1T5GA 4HXQA 1XFKA 4IXVA 5HJ9A 1WVAA 1ZPEA 4FCIA 5HJAA 3M1RA 4ITYA 1P8OA 4GWDA 4Q3VA 3E8ZA 4HWWA 3SL0A 1HQXA 2ZAVA 4Q3RC 4IE1A 1P8SA 3NIOA 4IU4A 4Q3UA 3NIQA 3MJLA 1WOIA 1ZPGA 1RLAA 3MFWA 2PHAA 3GMZA 1PQ3A 1HQ5A 3CEVA 4Q40A 1WOGA 4IXUA 1D3VA 1T4RA 3GN0A 4RHMA 1HQGA 4IU0A 1T5FA 4Q3TA 1P8RA 4Q3PA 5RLAA 4GSVA 1P8PA 3DJ8A 3E9BA 4FCKA 4RHIA 1T4SA 2A0MA 4RHKA 3TH7A 2AEBA 4RLAA 4I06A 3TF3A 4Q3SA 1HQFA 1HQHA 2EF5A 2RLAA 4CEVA 1T4PA 4IU5A 1T4TA 4MYFA 1GQ6A 3PZLA 2CEVA 3MMRA 4IE3A 3E6KA 4DZ4A 1CEVA 4RHJA 4MYLA 3RLAA 4Q3RA 3THHA 1TBJA 5CEVA 3F80A 4RHLA 3THEA 4Q3QA 1WOHA 3E6VA 4Q41A 4MXRA 1P8NA 4MYNA 3THJA 2EF4A 2PLLA 1P8QA 3SJTA 3SKKA 4RHQA 3SL1A 3MFVA 1R1OA 4GSMA 4GWCA 4IU1A 1TBHA 3KV2A 3NIPA 4MYKA 4GSZA 2PHOA 3LHLA 1TA1A 1P8MA 4HZEA 3E8QA 1WVBA 3LP7A
chains in the Genus database with same CATH superfamily
4CBYA 3LP4A 5ICNB 3MENA 2V5XA 5THVA 1C3SA 2EIVA 1TBLA 2VQVA 3Q9BA 4IE2A 5G1AA 5G3WA 4CQFA 3MAXA 4Q42A 2VQOA 3F06A 1GQ7A 1ZZ3A 3F07A 3ZNRA 4G3HA 1T5GA 2V5WA 3C0ZA 4HXQA 5A2SA 1XFKA 4IXVA 4QA3A 5HJ9A 1WVAA 1ZPEA 4FCIA 4ZURA 5EF7A 5HJAA 4A69A 5G0JA 5EFKB 3M1RA 5G0GA 1VKGA 4ITYA 1P8OA 5EFNA 3SFFA 4GWDA 4BZ9A 5EEIA 4Q3VA 3E8ZA 4HWWA 5THSA 1HQXA 2ZAVA 5G0YA 3SL0A 4Q3RC 4IE1A 1P8SA 1C3PA 3NIOA 4IU4A 3Q9EA 3MZ4A 4Q3UA 1T67A 3NIQA 4RN2A 3MJLA 1WOIA 5EFJD 4ZUMA 1ZPGA 4BZ6A 5EEMA 1RLAA 3EZTA 3MFWA 5FUEA 4BZ7A 1ZZ0A 2PHAA 3GMZA 1PQ3A 1HQ5A 3CEVA 4Q40A 1C3RA 1WOGA 3MZ7A 4IXUA 4CBTA 4QA1A 1D3VA 3MZ6A 4BZ5A 1T4RA 3C10A 3GN0A 4RHMA 1HQGA 2VCGA 3Q9CA 4BKXB 4IU0A 5LI3A 5EFGA 4ZUNA 1T5FA 1ZZ1A 1P8RA 4Q3PA 4Q3TA 5EENA 5RLAA 5G11A 1P8PA 3E9BA 3DJ8A 4FCKA 4GSVA 4RHIA 5G10A 1T4SA 2A0MA 4QA0A 4RHKA 5G0XA 3TH7A 2AEBA 4RLAA 4I06A 5DC8A 3TF3A 4Q3SA 1HQFA 3EZPA 3RQDA 1HQHA 2EF5A 2RLAA 4LXZA 5DC5A 1T4PA 5THTA 4CEVA 4IU5A 1T4TA 4MYFA 5THUA 2VQQA 5G17A 1GQ6A 3PZLA 3SFHA 4RN0A 5G0HA 4QA7A 4QA6A 5D1DA 2CEVA 3MMRA 5G12A 3ZNSA 4IE3A 3E6KA 4DZ4A 3EWFA 1CEVA 4RHJA 4MYLA 3RLAA 4Q3RA 3THHA 1TBJA 5CEVA 3F80A 1W22A 5G1CA 4RHLA 3THEA 4Q3QA 2VQJA 5BWZA 1WOHA 3Q9FA 3E6VA 5EEFA 4Q41A 4MXRA 4ZUQA 5EFBD 4QA4A 3EW8A 4LY1A 5D1BA 5IWGA 3MZ3A 1P8NA 4QA5A 4ZUPA 4BZ8A 5JI5A 4MYNA 3THJA 2EF4A 1T69A 2PLLA 5G13A 2VQWG 5FCWA 5IX0A 1P8QA 5D1CA 3SJTA 5DC7A 3SKKA 4RHQA 3SL1A 5EF8A 1T64A 3MFVA 1R1OA 5G0IA 4GSMA 4GWCA 2GH6A 4IU1A 5EEKA 1TBHA 4QA2A 3KV2A 3NIPA 4ZUOA 3C0YA 4MYKA 4GSZA 4RN1A 2PHOA 3LHLA 5EFHA 3F0RA 1TA1A 1P8MA 2VQMA 5G1BA 4HZEA 3E8QA 1WVBA 5DC6A 3LP7A
chains in the Genus database with same CATH topology
3LP4A 2EIVA 4IE2A 1TBLA 4Q42A 1GQ7A 4G3HA 1T5GA 4HXQA 1XFKA 4IXVA 5HJ9A 1WVAA 1ZPEA 4FCIA 5HJAA 3M1RA 4ITYA 1P8OA 4GWDA 4Q3VA 3E8ZA 4HWWA 3SL0A 1HQXA 2ZAVA 4Q3RC 4IE1A 1P8SA 3NIOA 4IU4A 4Q3UA 3NIQA 3MJLA 1WOIA 1ZPGA 1RLAA 3MFWA 2PHAA 3GMZA 1PQ3A 1HQ5A 3CEVA 4Q40A 1WOGA 4IXUA 1D3VA 1T4RA 3GN0A 4RHMA 1HQGA 4IU0A 1T5FA 4Q3TA 1P8RA 4Q3PA 5RLAA 4GSVA 1P8PA 3DJ8A 3E9BA 4FCKA 4RHIA 1T4SA 2A0MA 4RHKA 3TH7A 2AEBA 4RLAA 4I06A 3TF3A 4Q3SA 1HQFA 1HQHA 2EF5A 2RLAA 4CEVA 1T4PA 4IU5A 1T4TA 4MYFA 1GQ6A 3PZLA 2CEVA 3MMRA 4IE3A 3E6KA 4DZ4A 1CEVA 4RHJA 4MYLA 3RLAA 4Q3RA 3THHA 1TBJA 5CEVA 3F80A 4RHLA 3THEA 4Q3QA 1WOHA 3E6VA 4Q41A 4MXRA 1P8NA 4MYNA 3THJA 2EF4A 2PLLA 1P8QA 3SJTA 3SKKA 4RHQA 3SL1A 3MFVA 1R1OA 4GSMA 4GWCA 4IU1A 1TBHA 3KV2A 3NIPA 4MYKA 4GSZA 2PHOA 3LHLA 1TA1A 1P8MA 4HZEA 3E8QA 1WVBA 3LP7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LP4 A;  2EIV A;  4IE2 A;  1TBL A;  4Q42 A;  1GQ7 A;  4G3H A;  1T5G A;  4HXQ A;  1XFK A;  4IXV A;  5HJ9 A;  1WVA A;  1ZPE A;  4FCI A;  5HJA A;  3M1R A;  4ITY A;  1P8O A;  4GWD A;  4Q3V A;  3E8Z A;  4HWW A;  3SL0 A;  1HQX A;  2ZAV A;  4Q3R C;  4IE1 A;  1P8S A;  3NIO A;  4IU4 A;  4Q3U A;  3NIQ A;  3MJL A;  1WOI A;  1ZPG A;  1RLA A;  3MFW A;  2PHA A;  3GMZ A;  1PQ3 A;  1HQ5 A;  3CEV A;  4Q40 A;  1WOG A;  4IXU A;  1D3V A;  1T4R A;  3GN0 A;  4RHM A;  1HQG A;  4IU0 A;  1T5F A;  4Q3T A;  1P8R A;  4Q3P A;  5RLA A;  4GSV A;  1P8P A;  3DJ8 A;  3E9B A;  4FCK A;  4RHI A;  1T4S A;  2A0M A;  4RHK A;  3TH7 A;  2AEB A;  4RLA A;  4I06 A;  3TF3 A;  4Q3S A;  1HQF A;  1HQH A;  2EF5 A;  2RLA A;  4CEV A;  1T4P A;  4IU5 A;  1T4T A;  4MYF A;  1GQ6 A;  3PZL A;  2CEV A;  3MMR A;  4IE3 A;  3E6K A;  4DZ4 A;  1CEV A;  4RHJ A;  4MYL A;  3RLA A;  4Q3R A;  3THH A;  1TBJ A;  5CEV A;  3F80 A;  4RHL A;  3THE A;  4Q3Q A;  1WOH A;  3E6V A;  4Q41 A;  4MXR A;  1P8N A;  4MYN A;  3THJ A;  2EF4 A;  2PLL A;  1P8Q A;  3SJT A;  3SKK A;  4RHQ A;  3SL1 A;  3MFV A;  1R1O A;  4GSM A;  4GWC A;  4IU1 A;  1TBH A;  3KV2 A;  3NIP A;  4MYK A;  4GSZ A;  2PHO A;  3LHL A;  1TA1 A;  1P8M A;  4HZE A;  3E8Q A;  1WVB A;  3LP7 A; 
#chains in the Genus database with same CATH topology
 4CBY A;  3LP4 A;  5ICN B;  3MEN A;  2V5X A;  5THV A;  1C3S A;  2EIV A;  1TBL A;  2VQV A;  3Q9B A;  4IE2 A;  5G1A A;  5G3W A;  4CQF A;  3MAX A;  4Q42 A;  2VQO A;  3F06 A;  1GQ7 A;  1ZZ3 A;  3F07 A;  3ZNR A;  4G3H A;  1T5G A;  2V5W A;  3C0Z A;  4HXQ A;  5A2S A;  1XFK A;  4IXV A;  4QA3 A;  5HJ9 A;  1WVA A;  1ZPE A;  4FCI A;  4ZUR A;  5EF7 A;  5HJA A;  4A69 A;  5G0J A;  5EFK B;  3M1R A;  5G0G A;  1VKG A;  4ITY A;  1P8O A;  5EFN A;  3SFF A;  4GWD A;  4BZ9 A;  5EEI A;  4Q3V A;  3E8Z A;  4HWW A;  5THS A;  1HQX A;  2ZAV A;  5G0Y A;  3SL0 A;  4Q3R C;  4IE1 A;  1P8S A;  1C3P A;  3NIO A;  4IU4 A;  3Q9E A;  3MZ4 A;  4Q3U A;  1T67 A;  3NIQ A;  4RN2 A;  3MJL A;  1WOI A;  5EFJ D;  4ZUM A;  1ZPG A;  4BZ6 A;  5EEM A;  1RLA A;  3EZT A;  3MFW A;  5FUE A;  4BZ7 A;  1ZZ0 A;  2PHA A;  3GMZ A;  1PQ3 A;  1HQ5 A;  3CEV A;  4Q40 A;  1C3R A;  1WOG A;  3MZ7 A;  4IXU A;  4CBT A;  4QA1 A;  1D3V A;  3MZ6 A;  4BZ5 A;  1T4R A;  3C10 A;  3GN0 A;  4RHM A;  1HQG A;  2VCG A;  3Q9C A;  4BKX B;  4IU0 A;  5LI3 A;  5EFG A;  4ZUN A;  1T5F A;  1ZZ1 A;  1P8R A;  4Q3P A;  4Q3T A;  5EEN A;  5RLA A;  5G11 A;  1P8P A;  3E9B A;  3DJ8 A;  4FCK A;  4GSV A;  4RHI A;  5G10 A;  1T4S A;  2A0M A;  4QA0 A;  4RHK A;  5G0X A;  3TH7 A;  2AEB A;  4RLA A;  4I06 A;  5DC8 A;  3TF3 A;  4Q3S A;  1HQF A;  3EZP A;  3RQD A;  1HQH A;  2EF5 A;  2RLA A;  4LXZ A;  5DC5 A;  1T4P A;  5THT A;  4CEV A;  4IU5 A;  1T4T A;  4MYF A;  5THU A;  2VQQ A;  5G17 A;  1GQ6 A;  3PZL A;  3SFH A;  4RN0 A;  5G0H A;  4QA7 A;  4QA6 A;  5D1D A;  2CEV A;  3MMR A;  5G12 A;  3ZNS A;  4IE3 A;  3E6K A;  4DZ4 A;  3EWF A;  1CEV A;  4RHJ A;  4MYL A;  3RLA A;  4Q3R A;  3THH A;  1TBJ A;  5CEV A;  3F80 A;  1W22 A;  5G1C A;  4RHL A;  3THE A;  4Q3Q A;  2VQJ A;  5BWZ A;  1WOH A;  3Q9F A;  3E6V A;  5EEF A;  4Q41 A;  4MXR A;  4ZUQ A;  5EFB D;  4QA4 A;  3EW8 A;  4LY1 A;  5D1B A;  5IWG A;  3MZ3 A;  1P8N A;  4QA5 A;  4ZUP A;  4BZ8 A;  5JI5 A;  4MYN A;  3THJ A;  2EF4 A;  1T69 A;  2PLL A;  5G13 A;  2VQW G;  5FCW A;  5IX0 A;  1P8Q A;  5D1C A;  3SJT A;  5DC7 A;  3SKK A;  4RHQ A;  3SL1 A;  5EF8 A;  1T64 A;  3MFV A;  1R1O A;  5G0I A;  4GSM A;  4GWC A;  2GH6 A;  4IU1 A;  5EEK A;  1TBH A;  4QA2 A;  3KV2 A;  3NIP A;  4ZUO A;  3C0Y A;  4MYK A;  4GSZ A;  4RN1 A;  2PHO A;  3LHL A;  5EFH A;  3F0R A;  1TA1 A;  1P8M A;  2VQM A;  5G1B A;  4HZE A;  3E8Q A;  1WVB A;  5DC6 A;  3LP7 A; 
#chains in the Genus database with same CATH homology
 3LP4 A;  2EIV A;  4IE2 A;  1TBL A;  4Q42 A;  1GQ7 A;  4G3H A;  1T5G A;  4HXQ A;  1XFK A;  4IXV A;  5HJ9 A;  1WVA A;  1ZPE A;  4FCI A;  5HJA A;  3M1R A;  4ITY A;  1P8O A;  4GWD A;  4Q3V A;  3E8Z A;  4HWW A;  3SL0 A;  1HQX A;  2ZAV A;  4Q3R C;  4IE1 A;  1P8S A;  3NIO A;  4IU4 A;  4Q3U A;  3NIQ A;  3MJL A;  1WOI A;  1ZPG A;  1RLA A;  3MFW A;  2PHA A;  3GMZ A;  1PQ3 A;  1HQ5 A;  3CEV A;  4Q40 A;  1WOG A;  4IXU A;  1D3V A;  1T4R A;  3GN0 A;  4RHM A;  1HQG A;  4IU0 A;  1T5F A;  4Q3T A;  1P8R A;  4Q3P A;  5RLA A;  4GSV A;  1P8P A;  3DJ8 A;  3E9B A;  4FCK A;  4RHI A;  1T4S A;  2A0M A;  4RHK A;  3TH7 A;  2AEB A;  4RLA A;  4I06 A;  3TF3 A;  4Q3S A;  1HQF A;  1HQH A;  2EF5 A;  2RLA A;  4CEV A;  1T4P A;  4IU5 A;  1T4T A;  4MYF A;  1GQ6 A;  3PZL A;  2CEV A;  3MMR A;  4IE3 A;  3E6K A;  4DZ4 A;  1CEV A;  4RHJ A;  4MYL A;  3RLA A;  4Q3R A;  3THH A;  1TBJ A;  5CEV A;  3F80 A;  4RHL A;  3THE A;  4Q3Q A;  1WOH A;  3E6V A;  4Q41 A;  4MXR A;  1P8N A;  4MYN A;  3THJ A;  2EF4 A;  2PLL A;  1P8Q A;  3SJT A;  3SKK A;  4RHQ A;  3SL1 A;  3MFV A;  1R1O A;  4GSM A;  4GWC A;  4IU1 A;  1TBH A;  3KV2 A;  3NIP A;  4MYK A;  4GSZ A;  2PHO A;  3LHL A;  1TA1 A;  1P8M A;  4HZE A;  3E8Q A;  1WVB A;  3LP7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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