4Q3PA

Crystal structure of schistosoma mansoni arginase
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
345
structure length
336
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Arginase
total genus 125
structure length 336
sequence length 345
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q3pA00
3TH7A 4DZ4A 4MXRA 4Q3TA 4HZEA 4CEVA 2AEBA 4RHJA 1WOGA 1CEVA 4Q3QA 4GWDA 3E9BA 1WOHA 4FCIA 2PHAA 1T4PA 4Q40A 4Q3RC 1T5FA 3E6KA 1HQ5A 1ZPEA 2EF4A 3SL1A 3THEA 1P8PA 3NIOA 4Q41A 3MJLA 4IU4A 4I06A 4IXVA 4MYFA 3THJA 4HXQA 1XFKA 1HQGA 3NIPA 4GSMA 3E8QA 2EF5A 1T4SA 2PHOA 4ITYA 1TBHA 4IU0A 4G3HA 4Q3RA 5CEVA 1TBLA 3MFVA 1T5GA 4Q3VA 4Q3UA 2PLLA 1WOIA 1P8SA 1HQHA 3RLAA 3CEVA 3THHA 5HJAA 4RHLA 4RHIA 4RHQA 1P8QA 3LP7A 1ZPGA 4IE2A 4Q42A 1HQXA 3SL0A 1P8RA 4IU5A 3E8ZA 2CEVA 1TA1A 1T4RA 3GMZA 3GN0A 4GSVA 4MYNA 1P8NA 2EIVA 4IU1A 1GQ7A 3SJTA 3MMRA 4MYLA 4Q3SA 3MFWA 1T4TA 4RLAA 4GWCA 4Q3PA 3LHLA 3SKKA 3LP4A 3TF3A 1P8OA 4RHKA 3M1RA 2RLAA 3E6VA 1TBJA 4IE1A 4GSZA 5RLAA 1RLAA 1P8MA 1WVBA 4IXUA 4MYKA 1HQFA 1PQ3A 3PZLA 5HJ9A 4RHMA 1GQ6A 2A0MA 1D3VA 1R1OA 2ZAVA 3F80A 4FCKA 3KV2A 3DJ8A 1WVAA 4HWWA 4IE3A 3NIQA
chains in the Genus database with same CATH superfamily
5JI5A 3TH7A 3Q9CA 4DZ4A 2VQOA 5IX0A 4MXRA 4Q3TA 5G1CA 4HZEA 4QA1A 4CEVA 2AEBA 4CBYA 4RHJA 1WOGA 3ZNSA 1CEVA 5EEFA 3EWFA 4GWDA 4Q3QA 5EFNA 5G0JA 3E9BA 1ZZ1A 3F06A 1WOHA 4FCIA 5G13A 5DC7A 2VQWG 2PHAA 5EF7A 1T67A 5G10A 1T4PA 4Q40A 4A69A 5EEIA 5EF8A 3MAXA 4Q3RC 1T5FA 1C3RA 3E6KA 1HQ5A 1ZPEA 3MZ7A 2EF4A 4RN2A 1W22A 5EEKA 3SL1A 4RN0A 3THEA 1P8PA 4ZUQA 5G3WA 3NIOA 4Q41A 3MJLA 4IU4A 4I06A 4IXVA 4MYFA 5IWGA 5THVA 3THJA 5EENA 4HXQA 1XFKA 5FUEA 1HQGA 3NIPA 4GSMA 3E8QA 2EF5A 3EW8A 5G0HA 4BZ7A 1T4SA 5D1DA 2PHOA 4ITYA 5G0YA 1TBHA 4IU0A 4G3HA 4Q3RA 5CEVA 3C10A 5DC8A 1TBLA 4QA4A 3MFVA 1T5GA 4Q3VA 4ZURA 4Q3UA 4BZ8A 3F0RA 2V5WA 1ZZ0A 2PLLA 1WOIA 1P8SA 5EFHA 1VKGA 1HQHA 4ZUNA 3RLAA 3CEVA 5EFGA 3THHA 5HJAA 4RHLA 4RHIA 4RHQA 2VCGA 1P8QA 3LP7A 1ZPGA 3MZ3A 5FCWA 5ICNB 1T64A 3MZ6A 4IE2A 4Q42A 1HQXA 3SL0A 1P8RA 4IU5A 3E8ZA 2CEVA 3MENA 1TA1A 1T4RA 3EZTA 3GMZA 4QA3A 5DC6A 5EEMA 5G1BA 3GN0A 3F07A 4GSVA 4MYNA 1P8NA 2EIVA 3C0YA 4IU1A 4QA0A 1GQ7A 3SJTA 5G12A 2VQQA 3MMRA 4MYLA 5D1BA 4LY1A 3EZPA 4BZ6A 5G0XA 4Q3SA 3MFWA 5G11A 5D1CA 1T4TA 1T69A 4RLAA 3Q9FA 4GWCA 2VQMA 4ZUMA 5BWZA 4Q3PA 3LHLA 3SKKA 3LP4A 4BKXB 3TF3A 1P8OA 4RHKA 3M1RA 1C3SA 4BZ5A 2VQJA 2RLAA 5THTA 3SFFA 3E6VA 4QA7A 5THUA 1TBJA 3SFHA 4LXZA 5EFJD 4IE1A 5G17A 1ZZ3A 4GSZA 3Q9EA 5RLAA 5G0GA 4QA5A 5G1AA 1RLAA 3Q9BA 1P8MA 1WVBA 3ZNRA 4IXUA 2GH6A 4BZ9A 4MYKA 5G0IA 1HQFA 4CBTA 5THSA 1PQ3A 3MZ4A 5A2SA 1C3PA 5EFBD 5LI3A 3C0ZA 3PZLA 3RQDA 2V5XA 4QA6A 5HJ9A 4RHMA 1GQ6A 2A0MA 4QA2A 1D3VA 1R1OA 2VQVA 2ZAVA 5EFKB 3F80A 4FCKA 4ZUPA 3KV2A 3DJ8A 4CQFA 1WVAA 4HWWA 5DC5A 4IE3A 4ZUOA 3NIQA 4RN1A
chains in the Genus database with same CATH topology
3TH7A 4DZ4A 4MXRA 4Q3TA 4HZEA 4CEVA 2AEBA 4RHJA 1WOGA 1CEVA 4Q3QA 4GWDA 3E9BA 1WOHA 4FCIA 2PHAA 1T4PA 4Q40A 4Q3RC 1T5FA 3E6KA 1HQ5A 1ZPEA 2EF4A 3SL1A 3THEA 1P8PA 3NIOA 4Q41A 3MJLA 4IU4A 4I06A 4IXVA 4MYFA 3THJA 4HXQA 1XFKA 1HQGA 3NIPA 4GSMA 3E8QA 2EF5A 1T4SA 2PHOA 4ITYA 1TBHA 4IU0A 4G3HA 4Q3RA 5CEVA 1TBLA 3MFVA 1T5GA 4Q3VA 4Q3UA 2PLLA 1WOIA 1P8SA 1HQHA 3RLAA 3CEVA 3THHA 5HJAA 4RHLA 4RHIA 4RHQA 1P8QA 3LP7A 1ZPGA 4IE2A 4Q42A 1HQXA 3SL0A 1P8RA 4IU5A 3E8ZA 2CEVA 1TA1A 1T4RA 3GMZA 3GN0A 4GSVA 4MYNA 1P8NA 2EIVA 4IU1A 1GQ7A 3SJTA 3MMRA 4MYLA 4Q3SA 3MFWA 1T4TA 4RLAA 4GWCA 4Q3PA 3LHLA 3SKKA 3LP4A 3TF3A 1P8OA 4RHKA 3M1RA 2RLAA 3E6VA 1TBJA 4IE1A 4GSZA 5RLAA 1RLAA 1P8MA 1WVBA 4IXUA 4MYKA 1HQFA 1PQ3A 3PZLA 5HJ9A 4RHMA 1GQ6A 2A0MA 1D3VA 1R1OA 2ZAVA 3F80A 4FCKA 3KV2A 3DJ8A 1WVAA 4HWWA 4IE3A 3NIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TH7 A;  4DZ4 A;  4MXR A;  4Q3T A;  4HZE A;  4CEV A;  2AEB A;  4RHJ A;  1WOG A;  1CEV A;  4Q3Q A;  4GWD A;  3E9B A;  1WOH A;  4FCI A;  2PHA A;  1T4P A;  4Q40 A;  4Q3R C;  1T5F A;  3E6K A;  1HQ5 A;  1ZPE A;  2EF4 A;  3SL1 A;  3THE A;  1P8P A;  3NIO A;  4Q41 A;  3MJL A;  4IU4 A;  4I06 A;  4IXV A;  4MYF A;  3THJ A;  4HXQ A;  1XFK A;  1HQG A;  3NIP A;  4GSM A;  3E8Q A;  2EF5 A;  1T4S A;  2PHO A;  4ITY A;  1TBH A;  4IU0 A;  4G3H A;  4Q3R A;  5CEV A;  1TBL A;  3MFV A;  1T5G A;  4Q3V A;  4Q3U A;  2PLL A;  1WOI A;  1P8S A;  1HQH A;  3RLA A;  3CEV A;  3THH A;  5HJA A;  4RHL A;  4RHI A;  4RHQ A;  1P8Q A;  3LP7 A;  1ZPG A;  4IE2 A;  4Q42 A;  1HQX A;  3SL0 A;  1P8R A;  4IU5 A;  3E8Z A;  2CEV A;  1TA1 A;  1T4R A;  3GMZ A;  3GN0 A;  4GSV A;  4MYN A;  1P8N A;  2EIV A;  4IU1 A;  1GQ7 A;  3SJT A;  3MMR A;  4MYL A;  4Q3S A;  3MFW A;  1T4T A;  4RLA A;  4GWC A;  4Q3P A;  3LHL A;  3SKK A;  3LP4 A;  3TF3 A;  1P8O A;  4RHK A;  3M1R A;  2RLA A;  3E6V A;  1TBJ A;  4IE1 A;  4GSZ A;  5RLA A;  1RLA A;  1P8M A;  1WVB A;  4IXU A;  4MYK A;  1HQF A;  1PQ3 A;  3PZL A;  5HJ9 A;  4RHM A;  1GQ6 A;  2A0M A;  1D3V A;  1R1O A;  2ZAV A;  3F80 A;  4FCK A;  3KV2 A;  3DJ8 A;  1WVA A;  4HWW A;  4IE3 A;  3NIQ A; 
#chains in the Genus database with same CATH topology
 5JI5 A;  3TH7 A;  3Q9C A;  4DZ4 A;  2VQO A;  5IX0 A;  4MXR A;  4Q3T A;  5G1C A;  4HZE A;  4QA1 A;  4CEV A;  2AEB A;  4CBY A;  4RHJ A;  1WOG A;  3ZNS A;  1CEV A;  5EEF A;  3EWF A;  4GWD A;  4Q3Q A;  5EFN A;  5G0J A;  3E9B A;  1ZZ1 A;  3F06 A;  1WOH A;  4FCI A;  5G13 A;  5DC7 A;  2VQW G;  2PHA A;  5EF7 A;  1T67 A;  5G10 A;  1T4P A;  4Q40 A;  4A69 A;  5EEI A;  5EF8 A;  3MAX A;  4Q3R C;  1T5F A;  1C3R A;  3E6K A;  1HQ5 A;  1ZPE A;  3MZ7 A;  2EF4 A;  4RN2 A;  1W22 A;  5EEK A;  3SL1 A;  4RN0 A;  3THE A;  1P8P A;  4ZUQ A;  5G3W A;  3NIO A;  4Q41 A;  3MJL A;  4IU4 A;  4I06 A;  4IXV A;  4MYF A;  5IWG A;  5THV A;  3THJ A;  5EEN A;  4HXQ A;  1XFK A;  5FUE A;  1HQG A;  3NIP A;  4GSM A;  3E8Q A;  2EF5 A;  3EW8 A;  5G0H A;  4BZ7 A;  1T4S A;  5D1D A;  2PHO A;  4ITY A;  5G0Y A;  1TBH A;  4IU0 A;  4G3H A;  4Q3R A;  5CEV A;  3C10 A;  5DC8 A;  1TBL A;  4QA4 A;  3MFV A;  1T5G A;  4Q3V A;  4ZUR A;  4Q3U A;  4BZ8 A;  3F0R A;  2V5W A;  1ZZ0 A;  2PLL A;  1WOI A;  1P8S A;  5EFH A;  1VKG A;  1HQH A;  4ZUN A;  3RLA A;  3CEV A;  5EFG A;  3THH A;  5HJA A;  4RHL A;  4RHI A;  4RHQ A;  2VCG A;  1P8Q A;  3LP7 A;  1ZPG A;  3MZ3 A;  5FCW A;  5ICN B;  1T64 A;  3MZ6 A;  4IE2 A;  4Q42 A;  1HQX A;  3SL0 A;  1P8R A;  4IU5 A;  3E8Z A;  2CEV A;  3MEN A;  1TA1 A;  1T4R A;  3EZT A;  3GMZ A;  4QA3 A;  5DC6 A;  5EEM A;  5G1B A;  3GN0 A;  3F07 A;  4GSV A;  4MYN A;  1P8N A;  2EIV A;  3C0Y A;  4IU1 A;  4QA0 A;  1GQ7 A;  3SJT A;  5G12 A;  2VQQ A;  3MMR A;  4MYL A;  5D1B A;  4LY1 A;  3EZP A;  4BZ6 A;  5G0X A;  4Q3S A;  3MFW A;  5G11 A;  5D1C A;  1T4T A;  1T69 A;  4RLA A;  3Q9F A;  4GWC A;  2VQM A;  4ZUM A;  5BWZ A;  4Q3P A;  3LHL A;  3SKK A;  3LP4 A;  4BKX B;  3TF3 A;  1P8O A;  4RHK A;  3M1R A;  1C3S A;  4BZ5 A;  2VQJ A;  2RLA A;  5THT A;  3SFF A;  3E6V A;  4QA7 A;  5THU A;  1TBJ A;  3SFH A;  4LXZ A;  5EFJ D;  4IE1 A;  5G17 A;  1ZZ3 A;  4GSZ A;  3Q9E A;  5RLA A;  5G0G A;  4QA5 A;  5G1A A;  1RLA A;  3Q9B A;  1P8M A;  1WVB A;  3ZNR A;  4IXU A;  2GH6 A;  4BZ9 A;  4MYK A;  5G0I A;  1HQF A;  4CBT A;  5THS A;  1PQ3 A;  3MZ4 A;  5A2S A;  1C3P A;  5EFB D;  5LI3 A;  3C0Z A;  3PZL A;  3RQD A;  2V5X A;  4QA6 A;  5HJ9 A;  4RHM A;  1GQ6 A;  2A0M A;  4QA2 A;  1D3V A;  1R1O A;  2VQV A;  2ZAV A;  5EFK B;  3F80 A;  4FCK A;  4ZUP A;  3KV2 A;  3DJ8 A;  4CQF A;  1WVA A;  4HWW A;  5DC5 A;  4IE3 A;  4ZUO A;  3NIQ A;  4RN1 A; 
#chains in the Genus database with same CATH homology
 3TH7 A;  4DZ4 A;  4MXR A;  4Q3T A;  4HZE A;  4CEV A;  2AEB A;  4RHJ A;  1WOG A;  1CEV A;  4Q3Q A;  4GWD A;  3E9B A;  1WOH A;  4FCI A;  2PHA A;  1T4P A;  4Q40 A;  4Q3R C;  1T5F A;  3E6K A;  1HQ5 A;  1ZPE A;  2EF4 A;  3SL1 A;  3THE A;  1P8P A;  3NIO A;  4Q41 A;  3MJL A;  4IU4 A;  4I06 A;  4IXV A;  4MYF A;  3THJ A;  4HXQ A;  1XFK A;  1HQG A;  3NIP A;  4GSM A;  3E8Q A;  2EF5 A;  1T4S A;  2PHO A;  4ITY A;  1TBH A;  4IU0 A;  4G3H A;  4Q3R A;  5CEV A;  1TBL A;  3MFV A;  1T5G A;  4Q3V A;  4Q3U A;  2PLL A;  1WOI A;  1P8S A;  1HQH A;  3RLA A;  3CEV A;  3THH A;  5HJA A;  4RHL A;  4RHI A;  4RHQ A;  1P8Q A;  3LP7 A;  1ZPG A;  4IE2 A;  4Q42 A;  1HQX A;  3SL0 A;  1P8R A;  4IU5 A;  3E8Z A;  2CEV A;  1TA1 A;  1T4R A;  3GMZ A;  3GN0 A;  4GSV A;  4MYN A;  1P8N A;  2EIV A;  4IU1 A;  1GQ7 A;  3SJT A;  3MMR A;  4MYL A;  4Q3S A;  3MFW A;  1T4T A;  4RLA A;  4GWC A;  4Q3P A;  3LHL A;  3SKK A;  3LP4 A;  3TF3 A;  1P8O A;  4RHK A;  3M1R A;  2RLA A;  3E6V A;  1TBJ A;  4IE1 A;  4GSZ A;  5RLA A;  1RLA A;  1P8M A;  1WVB A;  4IXU A;  4MYK A;  1HQF A;  1PQ3 A;  3PZL A;  5HJ9 A;  4RHM A;  1GQ6 A;  2A0M A;  1D3V A;  1R1O A;  2ZAV A;  3F80 A;  4FCK A;  3KV2 A;  3DJ8 A;  1WVA A;  4HWW A;  4IE3 A;  3NIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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